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Relevant bibliographies by topics / 2-Chloro-3-formyl-quinoline

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Academic literature on the topic '2-Chloro-3-formyl-quinoline'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "2-Chloro-3-formyl-quinoline"

1

Peerzade, Nargisbano A., Shravan Y. Jadhav, and Raghunath B. Bhosale. "Synthesis and Biological Evaluation of Some Novel Quinoline based Chalcones as Potent Antimalarial, Anti-inflammatory, Antioxidant and Antidiabetic Agents." Asian Journal of Chemistry 32, no. 4 (2020): 959–64. http://dx.doi.org/10.14233/ajchem.2020.22542.

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The objective of the present study was to synthesize a series of some novel quinoline based methoxy substituted chalcones and to evaluate their in vitro antimalarial, anti-inflammatory, antioxidant and antidiabetic activitites. The quinoline based chalcones was synthesized by condensation of 2-chloro-3-formyl qunoline with various methoxy substituted acetophenone in presence of NaOH. The Claisen-Schmidt condensation gave high yield of quinoline based chalcones. Synthesis of 2-chloro-3-formyl quinoline was carried out by Vilsmeir-Haack reaction on acetanilide and 4-methoxy acetanilide which on

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2

Mashelkar, Uday, Mukesh Jha, and Beena Mashelkar. "Synthesis of 2-azetidinones substituted quinoline derivative." Journal of the Serbian Chemical Society 78, no. 5 (2013): 621–25. http://dx.doi.org/10.2298/jsc120617081m.

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Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones.

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3

Selvaraj, Mohana Roopan, Rahman Nawaz Khan Fazlur, and Elango Ganesh. "Antidermatophytic studies of some 2-chloro-quinoline analogues." Journal of Indian Chemical Society Vol. 92, Jun 2015 (2015): 851–53. https://doi.org/10.5281/zenodo.5636290.

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Chemistry Research Laboratory, Organic and Medicinal Chemistry Research Laboratory, Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore-632 014, Tamilnadu, India <em>E-mail </em>: nawaz_f@yahoo.co.in, mohanaroopan.s@vit.ac.in In this study, a series of 2-chloro-quinoline-3-carbaldehydes (1a-g) and (2-chloro-quinolin-3-yl)-methanols (2ag) were tested for their antidermatophytic studies against four species of dermatophytes : <em>T. rubrum</em>, <em>E. floccosum</em>, <em>T. mentagrophytes</em> and <em>M. gypseum</em> by well diffusion method. Compounds 1c, 1e and 2a

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4

Parab, R. H., and B. C. Dixit. "Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline." E-Journal of Chemistry 9, no. 3 (2012): 1188–95. http://dx.doi.org/10.1155/2012/164235.

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A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR,1HNMR,13CNMR spectra. Supplementary to these, they were assayedin vitrofor their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms.

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5

Ayoob, Ala, and Fatma Mohmood. "Synthesis of some new heterocyclic compounds derived from 2-Chloro-3-formyl quinoline." JOURNAL OF EDUCATION AND SCIENCE 26, no. 5 (2013): 75–85. http://dx.doi.org/10.33899/edusj.2013.163057.

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6

Beg, Nawaj Ali, and Maqdoom Farooqui. "Facile Synthesis of New Substituted 4-Thiazolidinones Conjugates containing Quinoline-Sulfamethoxazole Motifs and their Bioevaluation." Asian Journal of Chemistry 37, no. 2 (2025): 455–64. https://doi.org/10.14233/ajchem.2025.33177.

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Difunctional Brönsted acidic ionic liquid [DBN][HSO4] mediated synthesis of quinoline-sulfamethoxazole blended 4-thiazolidinones derivatives (7a-l) by reacting 4-amino-N-(5-methylisoxazol-3-yl) benzenesulfonamide (4), 2-chloro-3-formyl quinoline (5a-l) and mercapto acetic acid (6) in promising yields at 80 ºC. All the newly synthesized quinoline-sulfamethaoxazole incorporated 4-thiazolidinones derivatives were explored for their in vitro antifungal and antioxidant activity. The novel compounds, 4-thiazolidinones hybrids were evaluated against various fungal strains and compounds 7g, 7h, 7i, 7j

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7

Farrayeh, Batool A., Mustafa M. El-Abadelah, Jalal A. Zahra, Salim F. Haddad, and Wolfgang Voelte. "Heterocycles [h]-Fused onto 4-Oxoquinoline-3-carboxylic Acid. Part X [1]. Synthesis and X-Ray Structure of a Model 4- Oxo[1,4]benzoxazepino[2,3-h]quinoline-3-carboxylic Ester." Zeitschrift für Naturforschung B 68, no. 2 (2013): 187–94. http://dx.doi.org/10.5560/znb.2013-2270.

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Direct interaction of salicylaldehyde oxyanion with ethyl 7-chloro-8-nitro-4-oxoquinoline-3- carboxylate (2) delivered the respective 7-(2-formyl-phenoxy)-8-nitro-4-oxoquinoline-3-carboxylic ester 3. Reductive cyclization of 3 furnished the corresponding 4-oxo-[1,4]benzoxazepino[2,3- h]quinoline-3-carboxylic ester 5. Acid-catalyzed hydrolysis of the esters 3/5 produced the respective acids 4/6. Structural assignments for the new compounds 3 - 6 are supported by microanalytical and spectral (IR, HRMS, NMR) data and confirmed by X-ray structure determination for compound 5. Interestingly, compou

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8

Nayak, Govind, Birendra Shrivastava, and Akhlesh Singhai. "Synthesis and Antimicrobial Activity of Azetidin-2-One Fused 2-Chloro-3-Formyl Quinoline Derivatives." Oriental Journal of Chemistry 32, no. 4 (2016): 1977–82. http://dx.doi.org/10.13005/ojc/320423.

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9

Heravi;, Majid M., M. Shiri, Heravi M. Momahed, et al. "Pseudo-five-component condensation for the diversity-oriented synthesis of novel indoles and quinolines containing pseudo-peptides (tricarboxamides)." Iranian Journal of Chemistry and Chemical Engineering 37, no. 4 (2018): 101–15. https://doi.org/10.5281/zenodo.4052265.

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A novel series of indole and quinoline tricarboxamides were synthesized using simple and efficient one-pot pseudo-five-component reactions of 2-formylindole or 2-chloro-3-formyl quinolines, isocyanides, amines, and Meldrum’s acid as a CH-acid in CH<sub>2</sub>Cl<sub>2</sub> at room temperature. This conversion has been achieved via the construction of new bonds including two C-C bonds, two C-N bonds, and one C=O bond. Remarkably, three peptide bonds were formed through a domino sequence including Knoevenagel reaction, [1+4] cycloaddition, deacetonation and also, aminolysis reaction. Part

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10

Prasanna, B. M., B. M. Praveen, Narayana Hebbar, T. V. Venkatesha, and H. C. Tandon. "Inhibition study of mild steel corrosion in 1 M hydrochloric acid solution by 2-chloro 3-formyl quinoline." International Journal of Industrial Chemistry 7, no. 1 (2015): 9–19. http://dx.doi.org/10.1007/s40090-015-0064-6.

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