Relevant bibliographies by topics / 2-diamina

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic '2-diamina'

Author: Grafiati
Published: 24 April 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic '2-diamina.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "2-diamina"

1

Zaini, Mahirah, Rohah A. Majid, and Hossein Nikbakht. "Modification of Montmorillonite with Diamine Surfactants." Applied Mechanics and Materials 695 (November 2014): 224–27. http://dx.doi.org/10.4028/www.scientific.net/amm.695.224.

Full text
Abstract:
Sodium montmorillonite (Na-MMT) was modified with various type of diamine surfactants. The modification imparts hydrophobic characters of MMT, thus enhancing its compatibility and dispersibility in polymer matrix. In this research, pristine MMT was modified with three types of diamine surfactants, namely, 1,3 diaminopropane (DAP), 1,8 diamino octane (DAO) and 1,5 diamino-2-Methyl pentane (DAMP). These diamines have different molecular structures where DAP has a short linear structure, DAO has eight carbons while DAMP has a methyl branch on its backbone. The modification was carried via cationic exchange process. X-ray diffraction (XRD) analysis showed the enhancement of d-spacing of MMT galleries and the formation of intercalated structure with the incorporation of diamines. Overall, type of diamines did not give significant effect on the d-spacing values with DAMP-MMT exhibited a slightly higher d-spacing at 13. 36 Å. The presence of methyl branch on the DAMP backbone was thought provide more spacing for the diamine to intercalate through the MMT gallery. Meanwhile, the detection of –NH bending amine group at 1470 cm-1 on the Fourier infrared (FTIR) spectra, corresponding to the free surfactant tail, had confirmed the successfulness of cationic exchange reaction between the diamines and MMT surface.
APA, Harvard, Vancouver, ISO, and other styles
2

Acosta Beltrán, Sherly Catherin, Carlos E. Daza, and Carolina Blanco Jiménez. "Catalizadores tipo zinc(salen) y su aplicación en la copolimerización entre óxido de limoneno y CO2." Scientia et technica 24, no. 2 (June 30, 2019): 275. http://dx.doi.org/10.22517/23447214.16311.

Full text
Abstract:
En este trabajo se lleva a cabo la síntesis y caracterización de catalizadores tipo salen con Zn, los cuales son obtenidos mediante reacción de condensación entre una 1,2-diamina y 3,5-diterc-butilsalicilaldehído en presencia de acetato de zinc. Se obtuvieron rendimientos del 86% en la síntesis del catalizador Zn-salen-1, 60% para Zn-salen-2 y 70% para Zn-salen-3. Estos catalizadores fueron usados en la reacción de acoplamiento de óxido de limoneno con CO2. Los mejores resultados en términos de conversión (20%) se evidenciaron cuando el sistema catalítico Zn-salen-2/NBuI se evaluó usando 20 bar de CO2, 40°C durante 24 h. En todos los casos studiados, la reacción demostró ser completamente selectiva hacia la formación del policarbonato de limoneno. No se encontró dependencia significativa de la presión de CO2 en la determinación de la actividad del sistema catalítico examinado.
APA, Harvard, Vancouver, ISO, and other styles
3

Herbig, Marcus, Henrik Scholz, Uwe Böhme, Betty Günther, Lia Gevorgyan, Daniela Gerlach, Jörg Wagler, Sandra Schwarzer, and Edwin Kroke. "New cyclic and spirocyclic aminosilanes." Main Group Metal Chemistry 44, no. 1 (January 1, 2021): 51–72. http://dx.doi.org/10.1515/mgmc-2021-0007.

Full text
Abstract:
Abstract New cyclic and spirocyclic aminosilanes were synthesised using ethylenediamine, 2-aminobenzylamine, 1,8-diaminonaphthalene, o-phenylenediamine, and trans-cyclohexane-1,2-diamine as starting material. These diamines were converted into aminosilanes using silicon tetrachloride and dimethyldichlorosilane directly and via the N,N’-bis(trimethylsilylated) amino derivatives. 15 new compounds of the type (diamino)(SiMe3)2, (diamino)2Si, (diamino)SiMe2, and (diamino)SiCl2 have been prepared. The formation of two cyclotrisilazane derivatives was observed starting from (N,N’-2-aminobenzylamino)dichlorosilane by trimerisation. All synthesised compounds have been characterised with NMR-, Raman-, or IR-spectroscopy, mass-spectrometry, and boiling or melting point. Single-crystal X-ray structure analyses of several derivatives have been performed. The degree of substitution with trimethylsilyl groups in the final compounds depends on the ring size of the spirocycles. It was shown with quantum chemical calculations on the M062X/6-31G(d) level that trimethylsilyl groups have a stabilising effect on 5-membered ring systems and a destabilising effect on 6-membered rings in these compounds.
APA, Harvard, Vancouver, ISO, and other styles
4

Ali, Dr Firyal M., and Haider H. Rashed. "Poly-Condensation of CDTA with Some Diamines." Journal of Petroleum Research and Studies 4, no. 1 (June 1, 2013): 58–70. http://dx.doi.org/10.52716/jprs.v4i1.89.

Full text
Abstract:
In this research, new condensed polymers (A1-A8) were prepared by poly condensation between 1, 2-cyclohexyl diamine tetraacetic acid CDTA with different diamines such as 1, 6-Diamino hexane, Melamine, 3,3-,5,5--Tetramethyl benzidine, Benzidine and Cystine. These prepared chelate polymers could be used to remove heavy metals and toxic metal ions in many industrial processes as well as acting as sequestrate for metal ions. The all prepared polymers were characterized by 1H-NMR and FT-IR spectra. The thermal analyses (TGA, DSC) were studied, the intrinsic viscosities were calculated at 30 ˚C using Ostwald viscometer, and all physical properties were measured.
APA, Harvard, Vancouver, ISO, and other styles
5

Matsukizono, Hiroyuki, and Takeshi Endo. "Synthesis of Bi- and Trifunctional Cyclic Carbonates Based on Trimethylolpropane and Their Application to Networked Polyhydroxyurethanes." Journal of Materials Science Research 5, no. 3 (April 7, 2016): 11. http://dx.doi.org/10.5539/jmsr.v5n3p11.

Full text
Abstract:
<p class="1Body">The reaction of trimethylolpropane (TMP) and diphenyl carbonate gives three types of TMP-based six-membered cyclic carbonates (TMPCs) via phosgene-free route. TMPC having one hydroxyl group (TMPC-OH) reacted with terephthaloyl chloride or trimesoyl chloride to give bifunctional (Ph-TMPC<sub>2</sub>) or trifunctional cyclic carbonate monomers (Ph-TMPC<sub>3</sub>), respectively. The ring-opening polyaddition of Ph-TMPC<sub>2</sub> and conventional diamines efficiently proceeded without the cleavage of ester bonds to afford linear polyhydroxyurethanes (PHUs) with well-controlled molecular weights and polydispersities via isocyanate-free route. Moreover, the polyaddition of Ph-TMPC<sub>2</sub> and diamine at TMPC<sub>2</sub>/diamine feed ratio of 1.1 afforded PHUs having cyclic carbonate terminals, the hydroxyl side chains of which were easily reacted with acetic anhydride to give acetylated PHUs with cyclic carbonate terminals. On the other hand, the polyaddition at Ph-TMPC<sub>2</sub>/diamine feed ratio of 0.91 gave PHUs with amine terminals. The copolymerization of Ph-TMPC<sub>2</sub>, Ph-TMPC<sub>3</sub> and diamine gives PHUs comprising covalently-bridged networked structures. After DMF solutions of Ph-TMPC<sub>2</sub>, Ph-TMPC<sub>3</sub> and diamines were simply kept at 60 °C overnight, networked PHU films with well transparency were successfully fabricated. The PHU films prepared at different diamines showed similar transparency and thermal stability, while the mechanical properties were significantly affected by the methylene spacers of diamines.</p>
APA, Harvard, Vancouver, ISO, and other styles
6

PEC, Pavel, and Ivo FRESORT. "1,4-Diamino-2-butyne as the mechanism-based pea diamine oxidase inhibitor." European Journal of Biochemistry 209, no. 2 (October 1992): 661–65. http://dx.doi.org/10.1111/j.1432-1033.1992.tb17333.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Hawthorne, D. G., J. H. Hodgkin, M. B. Jackson, J. W. Loder, and T. C. Morton. "Preparation and characterization of some new diaminobisimides." High Performance Polymers 6, no. 4 (August 1994): 287–301. http://dx.doi.org/10.1088/0954-0083/6/4/001.

Full text
Abstract:
A series of stable diaminobisimides (DABIs) has been prepared as alternatives to simple aromatic diamines for use in the preparation of condensation polymers. These DABIs were prepared by reacting two moles of an aromatic diamine with one mole of a dianhydride under conditions that minimize side reactions and the formation of oligomers. In many cases, the pure DABI consisting of two moles of the diamine and one mole of the dianhydride (i.e. the 2:1 product) can be obtained free of oligomers (i.e. the 3:2, 4:3 etc products). The studies have shown that the major factor determining the yield and purity of a DABI is the extent of conjugation between the two amino groups in the starting diamine: to a lesser extent steric effects in the diamines also influence the product composition. The reaction conditions necessary to produce these new DABIs are described together with extensive characterization of these materials by FTIR,1H and 13C NMR and gel permeation chromatography. The results indicate that pure DABIs are more manageable materials than the impure. insoluble materials previously described in the literature and can be used successfully to produce useful high-temperature stable polymers.
APA, Harvard, Vancouver, ISO, and other styles
8

Bermejo, Manuel R., Rocío Carballido, M. Isabel Fernández-García, Ana M. González-Noya, Gustavo González-Riopedre, Marcelino Maneiro, and Laura Rodríguez-Silva. "Synthesis, Characterization, and Catalytic Studies of Mn(III)-Schiff Base-Dicyanamide Complexes: Checking the Rhombicity Effect in Peroxidase Studies." Journal of Chemistry 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/5465890.

Full text
Abstract:
The condensation of 3-methoxy-2-hydroxybenzaldehyde and the diamines 1,2-diphenylendiamine, 1,2-diamine-2-methylpropane and 1,3-propanediamine yielded the dianionic tetradentate Schiff base ligands N,N′-bis(2-hydroxy-4-methoxybenzylidene)-1,2-diphenylendiimine (H2L1), N,N′-bis(2-hydroxy-4-methoxybenzylidene)-1,2-diamino-2-methylpropane (H2L2) and N,N′-bis(2-hydroxy-4-methoxybenzylidene)-1,3-diaminopropane (H2L3) respectively. The organic compounds H2L1 and H2L2 have been characterized by elemental analysis, IR, 1H and 13C NMR spectroscopies and mass spectrometry electrospray (ES). The crystal structure of H2L2 in solid state, solved by X-ray crystallography, is highly conditioned in the solid state by two N-H•••N intramolecular interactions. The synthesis of three new manganese(III) complexes 1–3, incorporating these ligands, H2L1–H2L3, and dicyanamide (DCA), is reported. The complexes 1–3 have been physicochemically characterized by elemental analysis, IR and paramagnetic 1H NMR spectroscopy, ESI mass spectrometry, magnetic moment at room temperature and conductivity measurements. Complex 1 has been crystallographically characterized. The X-ray structure shows the self-assembly of the Mn(III)-Schiff base-DCA complex through µ-aquo bridges between neighbouring axial water molecules and also by π-π stacking interactions, establishing a dimeric structure. The manganese complexes were also tested as peroxidase mimics for the H2O2-mediated reaction with the water-soluble trap ABTS, showing complexes 1-2 relevant peroxidase activity in contrast with 3. The rhombicity around the metal ion can explain this catalytic behaviour.
APA, Harvard, Vancouver, ISO, and other styles
9

Yaramapa, Hari Babu, Cirandur Suresh Reddy, Venugopal Maralla, and Pedaiahgari Vasugovardhana Reddy. "New 2-aryloxy Macroheterocyclic Phosphates." Journal of Chemical Research 2005, no. 9 (September 2005): 587–89. http://dx.doi.org/10.3184/030823405774308880.

Full text
Abstract:
A new class of phosphorus macroheterocycles (4a–j) has been synthesised in two steps. The reaction of 1 mole of 3,4-diamino-1,2,5-oxadiazole (1) with 2 moles of aqueous formaldehyde gave a Schiff's base which subsequently underwent addition with 2 moles of 4-t-butylphenol in 1,4-dioxane, afforded N,N-bis-(5-t-butyl-2-hydroxybenzyl)furazan-3,4-diamine (2). Cyclisation of 2 in situ with various substituted aryl phosphorodichloridates (3a–j) in the presence of Et3N in THF afforded 13-membered macroheterocycles (4a–j) containing P, N, O and C in good yields.
APA, Harvard, Vancouver, ISO, and other styles
10

He, Zuwen, Durgesh V. Nadkarni, Lawrence M. Sayre, and Frederick T. Greenaway. "Mechanism-based inactivation of porcine kidney diamine oxidase by 1,4-diamino-2-butene." Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1253, no. 1 (November 1995): 117–27. http://dx.doi.org/10.1016/0167-4838(95)00158-q.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "2-diamina"

1

Amaral, Thaeny Costa. "Síntese, caracterização e estudo biológico de compostos de rutênio, platina, paládio e ouro com o ligante dicloridrato de N,N’-bis (tiofenil-2-metil) etano-1,2-diamina." Universidade Federal de Juiz de Fora (UFJF), 2017. https://repositorio.ufjf.br/jspui/handle/ufjf/5506.

Full text
Abstract:
Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-07-20T11:57:50Z No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5)
Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-08-09T12:26:57Z (GMT) No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5)
Made available in DSpace on 2017-08-09T12:26:57Z (GMT). No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5) Previous issue date: 2017-02-23
No presente trabalho foram descritas as sínteses e as caracterizações do ligante dicloridrato de N,N'-bis(tiofenil-2-metil)etano-1,2-diamina (BNHred.2HCl), dos seus complexos [RuCl2BNHred(PPh3)2], [PtCl2BNHred] e [PdCl2BNHred] e dos sais [BNHred.2H+][PtCl4] e [BNHred.2H+][Au(CN)2]2-. Os compostos foram caracterizados por análise elementar (C, H, N), técnicas espectroscópicas no IV, Raman e RMN (solução e estado sólido), difração de raios X (DRX) por policristais e cálculos de DFT. Para os complexos [PtCl2BNHred] e [PdCl2BNHred] os resultados obtidos pelas técnicas de caracterização corroboram que a coordenação ocorreu pelos átomos de nitrogênio do grupo NH e por dois íons cloretos formando complexos com estrutura quadrática. O complexo [RuCl2BNHred(PPh3)2] teve sua estrutura determinada por DRX por policristais onde foi encontrada a estrutura com geometria octaédrica, tendo o íon Ru(II) coordenado aos grupos NH, de forma quelato, duas PPh3 e dois íons cloreto. Os sais [BNHred.2H+][PtCl4] e [BNHred.2H+][Au(CN)2]2- também tiveram suas estruturas determinadas por DRX (policristais), onde o sal [BNHred.2H+][Au(CN)2]2- se cristaliza em um sistema cristalino ortorrômbico e grupo espacial Pnn2 e o sal [BNHred.2H+][PtCl4] cristaliza-se no sistema triclínico e grupo espacial P-1. Além desses compostos, também foi sintetizado e caracterizado o ligante dinitrato de N,N'-bis(tiofenil-2metil)etano-1,2-diamina (BNHred.2HNO3), no qual teve a estrutura cristalina determinada por DRX (policristais), pertencendo ao sistema cristalino monoclínico e grupo espacial P21/c. Testes biológicos contra Mycobacterium tuberculosis, de todos os compostos obtidos foram realizados, onde o sal [BNHred.2H+][Au(CN)2]2- apresentou o CIM90 de 2,31 mg/L.
The present work, syntheses and characterizations of the ligand N,N’-bis(tiophenyl-2methyl)ethane-1,2-diamino dichlorydrate (BNHred.2HCl), their [RuCl2BNHred(PPh3)2], [PtCl2BNHred] and [PdCl2BNHred] complexes and their [BNHred.2H+][PtCl4] and [BNHred.2H+][Au(CN)2]2- salts were described. The compounds were analyzed by elementare analysis (C, H and N), IR, Raman and NMR (in solution and solid state) spectroscopies as well by powder X ray diffraction and DFT calculations. The [PtCl2BNHred] and [PdCl2BNHred] complexes should be square planar geometry since ligand is coordinated by nitrogen atoms of the NH groups and the coordination sphere is completed by two chlorine ions. The octahedral [RuCl2BNHred(PPh3)2] complex structure was determined/refined by powder X ray diffraction where the Ru(II) ion is coordinated by ligand in chelate mode, also by two PPh3 molecules and by two chloride ions. The [BNHred.2H+][PtCl4] and [BNHred.2H+][Au(CN)2]2- salt structures were also solved by powder X ray diffraction. [BNHred.2H+][Au(CN)2]2- salt crystallizes in orthorhombic system and space group Pnn2, while the [BNHred.2H+][PtCl4] salt belongs to triclinic system and space group P-1. In addition, the ligand N,N’-bis(tiophenyl-2-methyl)ethane-1,2-diamino dinitrate (BNHred.2HNO3) was also synthetized and fully characterized. The BNHred.2HNO3 structure was obtained by powder X ray diffraction and presents a monoclinic crystalline system and space group P21/c. Biological tests against Mycobacterium tuberculosis of all the obtained compounds have been carried out, where the [BNHred.2H+][Au(CN)2]2- salt has been shown MIC90 at 2.31 mg/L.
APA, Harvard, Vancouver, ISO, and other styles
2

Silva, Silvioney Augusto da. "Síntese, caracterização e avaliação da atividade antituberculose de complexos de prata e zinco com a base de Schiff N,N´-bis(tiofenil-2-metilideno)etano-1,2-diamina." Universidade Federal de Juiz de Fora (UFJF), 2014. https://repositorio.ufjf.br/jspui/handle/ufjf/4321.

Full text
Abstract:
Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-05-03T12:13:21Z No. of bitstreams: 1 silvioneyaugustodasilva.pdf: 3241038 bytes, checksum: d4f2b4d15c91d1718bc8150d6be6d119 (MD5)
Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-05-13T13:23:41Z (GMT) No. of bitstreams: 1 silvioneyaugustodasilva.pdf: 3241038 bytes, checksum: d4f2b4d15c91d1718bc8150d6be6d119 (MD5)
Made available in DSpace on 2017-05-13T13:23:41Z (GMT). No. of bitstreams: 1 silvioneyaugustodasilva.pdf: 3241038 bytes, checksum: d4f2b4d15c91d1718bc8150d6be6d119 (MD5) Previous issue date: 2014-01-24
No presente trabalho a base de Schiff, N,N’-bis(tiofenil-2-metilideno)etano1,2-diamina (BNH), foi obtida a partir da reação de condensação entre etilenodiamina (en) e 2-tiofenocarboxaldeído (TCA) usando a proporção molar 1:2 (en:TCA). Dois novos complexos de prata(I) com BNH foram preparados reagindo BNH:AgNO3. Quando a proporção molar de 1:1 (M:L) foi usada, o complexo polimérico [Ag(BNH)NO3]n foi obtido, onde os íons Ag(I) são coordenados por 2 N (grupo imina) de dois ligantes diferentes e um oxigênio do grupo nitrato. Quando a proporção molar de 1:2 (M:L) foi usada um complexo monomérico e quelato - [Ag(BNH)2]NO3 foi obtido. Neste complexo os íons prata(I) são coordenados por 4 N (grupo imina) de dois ligantes. Da mesma forma, complexos de zinco(II) também foram testados, mas as reações entre o BNH e ZnCl2 em 1:1 ou 1:2 (M:L) resultam no mesmo complexo formulado como [Zn(Cl)2(BNH)], onde o BNH se coordena ao íon Zn(II) pelos átomos de N (imina) e dois íons cloro completam a tetracoordenação em torno do íon zinco(II). Os compostos foram caracterizados por análises elementar (C, H, N) e térmica (TG/DTA), técnicas espectroscópicas de IV, Raman, Ressonância Magnética Nuclear e difração de raios X por monocristal e policristais. Além dos dados estruturais, analíticos, e espectroscópicos, foram realizados estudos biológicos. As propriedades antibacterianas e citotóxicos do BNH e de seus três complexos metálicos foram testadas com base na atividade AntiMBT e IC50 utilizando células VERO. Além disso, dois ligantes – N,N’-bis(tiofenil2-metil)-etano-1,2-diamina (obtido pela redução do BNH) e seu derivado cloridrato, foram sintetizados e parcialmente caracterizados. Um sal de ouro(III) também foi obtido e caracterizado por simples reação entre o cloridrato da diamina e o sal K[AuCl4].
In the present work the Schiff base, N,N’-bis(thiophenyl-2-methylidene) ethane-1,2-diamine (BNH), was obtained from condensation reaction between ethylenediamine (en) and 2- thiophenecarboxaldehyde (TCA) using molar ratio1:2 (en:TCA). Two new silver(I) complexes with BNH were prepared by reacting BNH:AgNO3. When 1:1 molar ratio (M:L) was used, the polymeric complex [Ag(BNH)NO3]n is obtained where Ag(I) ions are coordinated by 2 N (imine group) from two different ligands and one oxygen from nitrate group. When 1:2 molar ratio (M:L) is used a monomeric and chelated complex – [Ag(BNH)2]NO3 was obtained. In this complex silver(I) ions are surrounded by 4 N (imine group) from two ligands. In the same way, the zinc(II) complexes were also tested, but the reactions between the BNH and ZnCl2 in 1:1 or 1:2 (M:L) result in the same complex formulated as [Zn(Cl)2(BNH)], where BNH is coordinated to Zn(II) ions by N (imine) and two chlorine ions complete the tetracoordination around zinc(II) ions. The compounds were characterized by elemental (C, H, N) and thermal analyzes (TG/DTA), IR, Raman, and Nuclear Magnetic Resonance spectroscopic techniques and X rays diffraction - monocrystal and powder. Besides the analytical, spectroscopic and structural data, the biological studies were performed. The antibacterial and cytotoxic properties of BNH and its three metal complexes were tested based on the activity Anti-MBT and IC50 using VERO cells. In addition, two ligands – N,N’-bis(thiophenyl-2-methyl)ethane-1,2-diamine (obtained by BNH reduction) and its hydrochloric derivative were synthesized and partially characterized. A gold(III) salt was also obtained and characterized by simple reaction between the diamine‘s hydrochloride and K[AuCl4] salt.
APA, Harvard, Vancouver, ISO, and other styles
3

Mitchell, Preston Lincoln. "The synthesis of novel C←2 chiral diamine ligands." Thesis, University of Southampton, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368126.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Jones, Marlon D. "CHIRAL 1, 2-DIAMINO GUESTS IN CHAIN REPLACEMENT PEPTIDOMIMETICS: A NEW HELICAL MOTIF." UKnowledge, 2007. http://uknowledge.uky.edu/gradschool_diss/487.

Full text
Abstract:
Peptides are short, sequence and length specific oligomers composed of small amino acid residues. Nature has refined these peptide sequences and their endogenous function through evolution. In addition, peptides have played an important role in medicine, which has lead to further research into developing peptides as lead pharmaceuticals (therapeutic peptides). Unfortunately, therapeutic peptides are inferior as drug candidates due to their low oral bioavailability; immunogenicity and potential to be attacked by peptidases. Fortunately, peptides can be modified by steric constraints, cyclization, and/or replacement of the peptide backbone itself creating a mimic (peptidomimetic) of the original peptide. Peptidomimetics are deliberately designed to have increased protease resistance, reduced immunogenicity and improved bioavailability when compared to the original endogenous peptide. One such peptide, Magainin is a O One such peptide, Magainin is a well-studied, a-helical peptide found in African clawed frogs. This peptide has antibiotic properties (against pathogenic bacteria), which partly arises from the hydrophilic portion of the peptide having basic amino acid side chains periodically disposed on one side of the a-helix. This property of magainin causes its attraction to negatively charged bacteria cell membranes. Unfortunately, as in the case of other antibiotics, pathogenic bacteria have developed effective countermeasures against magainin. We designed a peptidomimetic based on magainin and implemented a plan to determine what type of molecules could be assembled for a magainin mimic. We successfully utilized molecular modeling (Monte Carlo conformational search), as well as results from previous experiments to elucidate what type of molecules, as well as how many molecules would be necessary to create a novel helical-like magainin peptidomimetic. It was discovered that C2 symmetric diamines would be best at generating the helical-like motif and the amino acid lysine to generate the basic side chain. The next step was the successful connection of two C2 symmetric molecules via a urea linkage and then one more connection to a lysine (a-amino group) residue, creating a short sequence of oligoureas (trimers). Finally, attempts to connect the oligoureas trimers were attempted using a solid-phase synthesis approach to generate a functional magainin mimic.
APA, Harvard, Vancouver, ISO, and other styles
5

Blond, Aurélie. "Synthèse orientée vers la diversité de cis-1,3-diamines pipéridiniques et cyclohexaniques : ligands potentiels d’ARN." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05P617.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

AUJARD, ISABELLE. "Nouvelle synthese de diamines chirales de symetrie c#2. Utilisation des diamines dans des reactions d'oxydation et de reduction." Paris 6, 1996. http://www.theses.fr/1996PA066458.

Full text
Abstract:
La synthese de diamines 1,2 de symetrie c#2 s'effectue le plus souvent par couplage reducteur de l'imine correspondante et conduit generalement au melange equimoleculaire des diastereoisomeres d,1 et meso. Ce dernier est inutilisable en synthese asymetrique. Nous presentons une nouvelle methode de synthese facilement realisable a grande echelle (>200 g) de diamines secondaires chirales issues d'aldehydes aromatiques. Le couplage reducteur a lieu en presence de zinc associe au me#3sicl. Le melange equimoleculaire d,1/meso ainsi obtenu est ensuite isomerise, de facon simple et rapide, en diamine d,1 par le couple li metal/isoprene. Le dedoublement s'effectue avec de l'acide tartrique chiral. Lors de nos recherches sur l'isomerisation, nous avons observe que les aminals de ces diamines pouvaient etre oxydes en monoamides en presence d'alcool (meoh) et d'une quantite catalytique de palladium sur charbon. L'utilisation d'ultrasons permet une reaction douce et rapide. Associees a lialh#4, ces diamines peuvent egalement conduire a la reduction directe de derives d'acides carboxyliques en aldehydes. Les diamines sont utilisees pour modifier le pouvoir reducteur de l'hydrure et pieger sous forme d'aminal l'aldehyde forme in situ. Une hydrolyse acide de ces aminals libere ensuite l'aldehyde attendu
APA, Harvard, Vancouver, ISO, and other styles
7

Sillén, Sara. "Photodegradation study of 3,5-diamino-6-chloro- N-(2-(methylamino)ethyl)pyrazine-2-carboxamide using preparative SFC and LC-MS." Thesis, Uppsala universitet, Institutionen för farmaci, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-301500.

Full text
Abstract:
In this project the photodegradation of 3,5-diamino-6-chloro-N-(2-(methylamino)ethyl)pyrazine-2-carboxamide was studied. A hypothetical degradation pattern for the compound was proposed and the aim of the project was to study the formed secondary photodegradants and to, if possible, structure elucidate some of these compounds. In order to do this, the parent compound was photodegraded in two steps, where a primary photodegradant was isolated using semi-preparative supercritical fluid chromatography (SFC) and then further degraded into the secondary photodegradants. The photodegradation was first carried out in aqueous solution, where the parent compound was irradiated in UV-A light of 300-400 nm. This resulted in a primary photodegradant with a molecular ion of m/z = 227, where the chloride in position 6 of the pyrazine group had been replaced by a hydroxyl group. During the large scale photodegradation, prior to the preparative purification, the yield of primary photodegradant was very low due to the photodegradation being dependent on both sample volume and concentration and due to the primary photodegradant also being unstable in aqueous solution at room temperature. Due to the above mentioned difficulties the parent compound was photodegraded in methanol instead of water in order to avoid the freeze-drying process where a lot of the primary photodegradant was lost. This resulted in a primary photodegradant with a molecular ion of m/z = 241, where the chloride had been replaced by a methoxy group instead of a hydroxyl group. This compound was more stable which allowed workup by rotary evaporation, instead of freeze-drying, before the preparative purification. This primary photodegradant was isolated using semi-preparative SFC on a Viridis® BEH Prep OBD TM column (250 x 30 mm, 5 µm) and a Luna HILIC column (250 x 30 mm, 5 µm) with MeOH/NH3 100/1 v/v as organic modifier. About 1.2 mg material was isolated and further photodegradation tests in ordinary water and 18O-water were conducted. Some secondary photodegradants were observed in LC-MS analyses, and their element compositions were proposed by accurate mass results. Fundamental structures for these compounds were proposed. Further structural investigational analyses are needed for confirmation in the future.
APA, Harvard, Vancouver, ISO, and other styles
8

Llop, Escorihuela Esther. "Structural analysis of eythropoietin glycans." Doctoral thesis, Universitat Pompeu Fabra, 2008. http://hdl.handle.net/10803/7129.

Full text
Abstract:
La eritropoyetina o EPO es una hormona glicoproteica. En los seres humanos adultos, se produce principalmente en el riñón, en respuesta a la reducción de oxígeno en los tejidos (hipoxia tisular). La EPO estimula la eritropoyesis, es decir, estimula a las células madre de la médula ósea para que aumenten la producción de eritrocitos. La molécula de EPO está formada por una cadena peptídica de 165 aminoácidos que contiene dos puentes disulfuro, un O-glicano (Ser-126), y tres N-glicanos (Asn-24, 38, 83). En conjunto, la glicosilación de esta proteína representa aproximadamente el 40% del peso total (29.4 kDa). La EPO sintetizada con tecnología recombinante (rEPO) se administra como fármaco, desde el año 1989, para el tratamiento de anemias, insuficiencia renal, cancer etc. También se ha observado la utilización de rEPO en deportistas con el fin de aumentar el suministro de oxígeno a los tejidos y así incrementar el rendimiento en deportes de resistencia. En el año 2001, se comercializó una "nueva proteína estimuladora de la eritropoyesis" llamada NESP. Esta proteína es un análogo hiperglicosilado de la EPO que posee dos N-glicanos adicionales (Asn-30, 88). El número y composición de los N-glicanos es muy importante para el metabolismo de estas glicoproteínas, ya que el contenido de carbohidratos (número de ácidos siálicos) determina su vida media. Los métodos que se utilizan actualmente para diferenciar la eritropoyetina endógena urinaria (uEPO) de sus análogos recombinantes (rEPO, NESP) están basados en las diferencias que existen entre sus perfiles isoelectroforéticos (IEF). Se cree que estas diferencias provienen de las células y/o especies en las que se expresan estas glicoproteínas. En este estudio, se llevo a cabo la caracterización estructural de diferentes preparaciones de EPO recombinante. Para ello, se utilizaron las técnicas más comunes en el campo de la glicoproteómica además de otras nuevas, desarrolladas para poder analizar los glicanos de muestras procedentes de geles 2-DE. Los perfiles de glicosilación total de cada una de estas glicoproteínas mostraron características estructurales que pueden facilitar la detección de rEPO y NESP en atletas que abusan de estas sustancias. Un ejemplo es la presencia de Neu5Gc únicamente en fármacos que han sido expresados en células CHO. La metodología desarrollada en este trabajo, podría emplearse también, para el control de calidad de estos fármacos y para el diagnóstico de ciertas patologías.
Erythropoietin (EPO) is a glycoprotein hormone secreted primarily by adult kidneys in response to tissue hypoxia. It is involved in the maturation and ultimately regulation of the level of red blood cells. The EPO molecule comprises a single polypeptide chain of 165 aminoacids with two disulfide bonds, 1 O-linked (Ser-126), and 3 N-linked (Asn-24, 38, 83) glycans representing about 40% of the total mass (29.4 kDa). The recombinant analogue (rEPO), available since 1989 has found widespread use in the treatment of anaemia, renal failure, cancer etc. Besides, rEPO is illicitly used by athletes to boost the delivery of oxygen to the tissue and enhance performance in endurance sports. In 2001, a novel erythropoiesis-stimulating protein (NESP) was also marketed. NESP possesses two additional N-glycans (Asn-30, 88). The number and composition of the N-glycans is very important in the metabolism of this glycoprotein because the carbohydrate content (sialylation degree) determines its half-life time. Current tests to differentiate between urinary endogenous (uEPO) and its recombinant analogues (rEPO, NESP) are based on differences in their iso-electric focussing (IEF) profiles. Those differences are believed to stem from the cells/species in which they are expressed. In this study, the structural characterisation of different rEPO preparations was conducted using standard techniques in the field and developing new ones to address glycans from 2-DE sample preparations. Overall glycosylation profiling of each glycoprotein revealed structural features that may pave the way to the unambiguous detection of rEPOs and NESP abuse, such as the presence of Neu5Gc in CHO cell derived drugs only, and the developed methodology may be also employed for maintaining pharmaceutical quality control and for diagnosing pathologic conditions.
APA, Harvard, Vancouver, ISO, and other styles
9

Weder, Christoph. "Synthese und Charakterisierung neuer Polyamide mit stabilen nichtlinear optischen Eigenschaften, basierend auf 2',5'-Diamino-4-(dimethylamino)-4'-nitrostilben /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10749.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Hing, Sherry Ann Ong 1957. "COPPER DEFICIENCY AND HYPERLIPOPROTEINEMIA INDUCED BY N,N'-BIS-(2-AMINOETHYL)-1,3-PROPANE DIAMINE (2,3,2-TETRAMINE) IN RABBITS (CHELATORS)." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276804.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "2-diamina"

1

Huang, Sung-ben. Synthesis and oligomerization of Delta, 4-diamino-2-oxo-1(2H)-pyrimidinehexanoic acid. 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Nelson, Jeffrey Stephen. Synthesis and oligomerization of y,4-Diamino-2-oxo-1(2H)-pyrimidinepentanoic acid. 1989.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "2-diamina"

1

Winkelmann, J. "Diffusion of ethane-1,2-diamine (1); air (2)." In Gases in Gases, Liquids and their Mixtures, 921. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-49718-9_623.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Wohlfarth, Ch. "Viscosity of the mixture (1) water; (2) ethane-1,2-diamine." In Supplement to IV/18, 747–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_451.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Wohlfarth, Ch. "Viscosity of the mixture (1) water; (2) propane-1,3-diamine." In Supplement to IV/18, 787–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_463.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Wohlfarth, Ch. "Viscosity of the mixture (1) water; (2) propane-1,2-diamine." In Supplement to IV/18, 783–86. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_462.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Pardasani, R. T., and P. Pardasani. "Magnetic properties of diamine-bis(2-hydroxynaphthaldehydo)ruthenium(III) bromide." In Magnetic Properties of Paramagnetic Compounds, 457. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53971-2_236.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ferragina, C., A. La Ginestra, M. A. Massucci, P. Cafarelli, P. Patrono, and A. A. G. Tomlinson. "Formation of Diamine-Complex Pillars in τ-Ti (HPO4) 2 2H2O." In Recent Developments in Ion Exchange, 103–8. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0777-5_11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Wohlfarth, Ch. "Viscosity of the mixture (1) ethane-1,2-diamine; (2) triethylene glycol." In Supplement to IV/18, 1494. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_863.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Pardasani, R. T., and P. Pardasani. "Magnetic properties of diamine-bis[N-(2-hydroxybenzanilide)]ruthenium(III) bromide." In Magnetic Properties of Paramagnetic Compounds, 460–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53971-2_238.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Winkelmann, J. "Diffusion of nitrous oxide (1); water (2); ethane-1,2-diamine (3)." In Gases in Gases, Liquids and their Mixtures, 2222. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-49718-9_1723.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Wohlfarth, Ch. "Viscosity of the mixture (1) water; (2) N,N-dimethylpropane-1,3-diamine." In Supplement to IV/18, 898–901. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_500.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "2-diamina"

1

Chen, Chenggang. "Factors Influencing the Morphology Development of Epoxy Nanocomposites." In ASME 2006 Multifunctional Nanocomposites International Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/mn2006-17083.

Full text
Abstract:
Polymer nanocomposites draw great interest due to their unique nanostructures and improved properties [1–2]. Epoxy is a widely-used thermosetting material. The research on the epoxy layered-silicate epoxy nanocomposite has exploded in the last decade [3–9]. The morphology of nanocomposites is the key to making high-performance nanocomposites. In this presentation, the factors influencing the morphology development behavior of epoxy nanocomposites will be discussed. The factors to be investigated include organoclay, epoxide, and curing agent. In this study, the aliphatic diamine (Jeffamines) with different molecular weights and aromatic diamine were selected as the curing agents, S30B (quaternary onium-montmorillonite) and SC18 (primary oniummont-morillonite) as the organoclays, and Epon 862 and Epon 828 as epoxides. In situ small-angle x-ray scattering (SAXS) was utilized to study the morphology development of the epoxy nanocomposite.
APA, Harvard, Vancouver, ISO, and other styles
2

Araujo, Ana R. Hornillo, Dolorès Edmont, and David M. Williams. "Synthesis and applications of a tricyclic analogue of N6-methoxy-2,6-diamino-2'-deoxyriboside." In XIIth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2002. http://dx.doi.org/10.1135/css200205328.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Lanzetta, Rosa, Maria Michela Corsaro, and Salvatore Ummarino. "5,7-DIAMINO-5,7,9-TRIDEOXYNON-2-ULOSONIC ACID: A NOVEL SUGAR FROM A PHYTOPATHOGENIC PSEUDOMONAS LIPOPOLYSACCHARIDE." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.530.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Fernández, M., M. Rodríguez-Doutón, M. Maneiro, A. González-Noya, B. Fernández, and M. Vázquez- Fernández. "SYNTHESIS OF DICOMPARTIMENTAL SCHIFF BASE LIGANDS. CRYSTAL STRUCTURE OF (N-N'-BIS(3- METHOXY or 3-ETHOXYSALICYLIDENE)-1,2-DIAMINE-2-METHYLPROPANE." In The 14th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00437.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Yang, Shu-Ping, Li-Jun Han, Zhuan Gao, and Yan Pan. "Spectroscopic Studies on the Interaction of A dichlorido-bridged dinuclear copper(II) complex [Cu2Cl4(C17H20Cl2N2)2] of diamine with bovine serum albumin." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE 2011). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5965798.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Franich, Andjela, Ivana Vasić, Snežana Rajković, Aleksandar Arsenijević, Marija Milovanović, Nebojša Arsenijević, Jelena Milovanović, and Marija Živković. "CYTOTOXICITY OF CATIONIC DINUCLEAR PLATINUM(II) COMPLEXES IN AN EXPERIMENTAL MODEL OF MOUSE COLON CANCER." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.293f.

Full text
Abstract:
The series of nine dinuclear platinum(II) complexes, [{Pt(L)Cl}2(μ-X)]2+ (where L is two NH3 or bidentantly coordinated diamine ligand – ethylenediamine, en; (±)-1,2-propylenediamine, 1,2-pn; isobutylenediamine, ibn; trans-(±)-1,2-diaminocyclohexane, dach; 1,3-propylenediamine, 1,3-pd; 2,2- dimethyl-1,3-propylenediamine, 2,2-diMe-1,3-pd; (±)-1,3-pentanediamine,1,3-pnd, and X is a bridging pyrazine (pz) or pyridazine (pydz) ligand) have been synthesized and characterized. The antitumor potential of these complexes against CT26 cells were determined by in vitro and in vivo assays. A murine model of heterotopic colon cancer tumor was induced in immunocompetent BALB/c mice for investigating antitumor potential of the Pt(II) complexes in vivo. It was found that complexes Pt1, Pt2 and Pt7 shows significant in vitro cytotoxic activity against mouse colon carcinoma CT26 cells, while all these complexes show moderate apoptotic effect. Complexes Pt1 and Pt7 arrested CT26 cells in G2/M phase of cell cycle, while complexes Pt5 and Pt6 exerted the highest antiproliferative effect which was evaluated by detection of Ki67 expressing cells. Complexes Pt1 and Pt2 performed significant in vivo antitumor effects reducing the growth of primary tumor and the incidence of lung and liver metastases without causing the significant hepato- and nephro- toxicity.
APA, Harvard, Vancouver, ISO, and other styles
7

Wolinska-Grabczyk, A., J. Muszynski, and Piotr Penczek. "Synthesis and phase behavior of novel poly(urethane-urea)s based on 4,4'-bis(2-hydroxyethoxy)biphenyl, 2,4-tolylene di-isocyanate and poly(oxypropylene)diamines." In Liquid Crystals, edited by Marzena Tykarska, Roman S. Dabrowski, and Jerzy Zielinski. SPIE, 1998. http://dx.doi.org/10.1117/12.301307.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

McClung, Amber J. W., Joseph A. Shumaker, and Jeffery W. Baur. "Novel Bismaleimide-Based Shape Memory Polymers: Comparison to Commercial Shape Memory Polymers." In ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/smasis2011-5044.

Full text
Abstract:
A series of novel shape memory polymers, synthesized from 4-4-bismaleimidodiphenyl-methane, an extended chain aliphatic diamine, and a bis-isocyanate, have been created and characterized with the aim of providing a family of robust high temperature shape memory polymers with tailorable transition temperatures for use in reconfigurable aerospace structures. In the present study, three of the polymers are chosen for more detailed study of their thermomechanical properties. These materials are compared to commercial resins Veriflex® and Veriflex-E® which are styrene- and epoxy-based proprietary formulations, respectively. The thermal and mechanical properties are determined utilizing thermogravimetric analysis and dynamic mechanical analysis. The temperatures at which 2% weight loss is observed in dry air ranges from 272 to 305 °C for the synthesized polymers, and occurs at 242 and 317 °C for the commercial Veriflex® and Veriflex-E® respectively. The glass transition temperatures, as measured by the peak in the tan(δ) curve, for the synthesized polymers range from 110 to 144 °C which is a higher than the Veriflex® and Veriflex-E® achieve at 84.3 and 100 °C respectively. With operation temperatures of subsonic structural aircraft components often reaching 121 °C (250 °F), the transition temperatures of the bismaleimide-based shape memory polymers are clearly desirable to ensure that shape memory polymers used in aircraft structures will not be prematurely triggered by the existing heat loads. In addition, the shape memory performance of the bismaleimide-based shape memory polymers compares well with the Veriflex® and Veriflex-E® resins.
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "2-diamina"

1

Byrd, Edward F. Theoretical Prediction of the Heats of Formation, Densities, and Relative Sensitivities for 2-(azidomethyl)-2-nitropropane-1,3-diyl dinitrate (AMDNNM), bis- aminofurazan diamino-octanitro-azobenzene (BAFDAONAB), and bis-nitrofurazan diamino-octanitro-azobenzene (BNFDAONAB). Fort Belvoir, VA: Defense Technical Information Center, March 2016. http://dx.doi.org/10.21236/ad1007813.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic '2-diamina' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography