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Journal articles on the topic '2-hydroxyisobutyric acid'

Author: Grafiati

Published: 4 June 2021

Last updated: 22 February 2023

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1

Rohwerder, Thore, and Roland H. Müller. "Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon." Microbial Cell Factories 9, no. 1 (2010): 13. http://dx.doi.org/10.1186/1475-2859-9-13.

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2

Kikunaga, H., T. Yoshimura, T. Kuribayashi, et al. "Separation of Am(III), Cm(III), and Cf(III) using capillary electrophoresis." Proceedings in Radiochemistry 1, no. 1 (2011): 167–71. http://dx.doi.org/10.1524/rcpr.2011.0031.

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AbstractTrivalent actinides Am(III), Cm(III), and Cf(III) were successfully separated for the first time using capillary electrophoresis in 2-hydroxyisobutyric acid/acetic acid. It was found that the ionic radius was primarily important for separation of trivalent actinides as well as lanthanides in this condition. The stability constants of the Am(III) complexes with 2-hydroxyisobutyrate were estimated using the correlations between the molar fraction ratio of lanthanides and their ionic radii.

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3

Kim, Sangwon, Jimin Yun, JeongHyun Cho, et al. "Self-catalyzed esterification of 2-hydroxyisobutyric acid: A simple method to produce methyl 2-hydroxyisobutyrate." Molecular Catalysis 532 (November 2022): 112721. http://dx.doi.org/10.1016/j.mcat.2022.112721.

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4

Mardinoglu, Adil, Silvia Gogg, Luca A. Lotta, et al. "Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes." EBioMedicine 27 (January 2018): 151–55. http://dx.doi.org/10.1016/j.ebiom.2017.12.008.

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5

Weichler, Maria-Teresa, Nadya Kurteva-Yaneva, Denise Przybylski, et al. "Thermophilic Coenzyme B12-Dependent Acyl Coenzyme A (CoA) Mutase from Kyrpidia tusciae DSM 2912 Preferentially Catalyzes Isomerization of (R)-3-Hydroxybutyryl-CoA and 2-Hydroxyisobutyryl-CoA." Applied and Environmental Microbiology 81, no. 14 (2015): 4564–72. http://dx.doi.org/10.1128/aem.00716-15.

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ABSTRACTThe recent discovery of a coenzyme B12-dependent acyl-coenzyme A (acyl-CoA) mutase isomerizing 3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA in the mesophilic bacteriumAquincola tertiaricarbonisL108 (N. Yaneva, J. Schuster, F. Schäfer, V. Lede, D. Przybylski, T. Paproth, H. Harms, R. H. Müller, and T. Rohwerder, J Biol Chem 287:15502–15511, 2012,http://dx.doi.org/10.1074/jbc.M111.314690) could pave the way for a complete biosynthesis route to the building block chemical 2-hydroxyisobutyric acid from renewable carbon. However, the enzyme catalyzes only the conversion of the stereoisomer

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6

Hoefel, Torben, Eva Wittmann, Liv Reinecke, and Dirk Weuster-Botz. "Reaction engineering studies for the production of 2-hydroxyisobutyric acid with recombinant Cupriavidus necator H 16." Applied Microbiology and Biotechnology 88, no. 2 (2010): 477–84. http://dx.doi.org/10.1007/s00253-010-2739-4.

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7

Deepitha, J., K. C. Pitchaiah, G. Chandrasekhar, and N. Sivaraman. "Solubility studies on 2-hydroxyisobutyric acid in supercritical carbon dioxide: Solubility evaluation and application to actinide extraction." Separation and Purification Technology 283 (January 2022): 120174. http://dx.doi.org/10.1016/j.seppur.2021.120174.

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8

León, Rosa, Duarte M. F. Prazeres, Francesco Molinari та Joaquim M. S. Cabral. "Microbial Stereoselective Oxidation of 2-methyl-1,3-propanediol to (R)-β-hydroxyisobutyric Acid in Aqueous/organic Biphasic Systems". Biocatalysis and Biotransformation 20, № 3 (2002): 201–7. http://dx.doi.org/10.1080/10242420290020723.

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9

Zahn, Michael, Nadya Kurteva-Yaneva, Judith Schuster, et al. "Structures of 2-Hydroxyisobutyric Acid-CoA Ligase Reveal Determinants of Substrate Specificity and Describe a Multi-Conformational Catalytic Cycle." Journal of Molecular Biology 431, no. 15 (2019): 2747–61. http://dx.doi.org/10.1016/j.jmb.2019.05.027.

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10

Leon, R., D. M. F. Prazeres, P. Fernandes, F. Molinari та J. M. S. Cabral. "A Multiphasic Hollow Fiber Reactor for the Whole-Cell Bioconversion of 2-Methyl-1,3-propanediol to (R)-β-Hydroxyisobutyric Acid". Biotechnology Progress 17, № 3 (2001): 468–73. http://dx.doi.org/10.1021/bp010015g.

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11

Przybylski, Denise, Thore Rohwerder, Cornelia Dilßner, Thomas Maskow, Hauke Harms, and Roland H. Müller. "Exploiting mixtures of H2, CO2, and O2 for improved production of methacrylate precursor 2-hydroxyisobutyric acid by engineered Cupriavidus necator strains." Applied Microbiology and Biotechnology 99, no. 5 (2014): 2131–45. http://dx.doi.org/10.1007/s00253-014-6266-6.

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12

Heller, Melina, Luciano Vitali, Mariana A. Siqueira, Alysson V. F. Sako, Marcel Piovezan, and Gustavo A. Micke. "Capillary Electrophoresis with UV Detection to Determine Cocaine on Circulated Banknotes." ISRN Analytical Chemistry 2013 (December 19, 2013): 1–7. http://dx.doi.org/10.1155/2013/489705.

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A new methodology employing capillary electrophoresis with UV detection (CE-UV) was developed, validated, and applied to determine the presence of cocaine on Brazilian banknotes. Some of the banknotes analyzed were obtained directly from general circulation (well used) while others were collected from Automated Teller Machines (ATMs) (relatively new). The background electrolyte optimized using Peakmaster 5.1 software was composed of 60 mmol L−1 TRIS(hydroxymethyl)aminomethane and 20 mmol L−1 2-hydroxyisobutyric acid, at pH 8.4. The separation time achieved for cocaine was only 2.5 minutes. The

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13

Ferreira, Nicolas Lopes, Diane Labbé, Frédéric Monot, Françoise Fayolle-Guichard, and Charles W. Greer. "Genes involved in the methyl tert-butyl ether (MTBE) metabolic pathway of Mycobacterium austroafricanum IFP 2012." Microbiology 152, no. 5 (2006): 1361–74. http://dx.doi.org/10.1099/mic.0.28585-0.

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Methyl tert-butyl ether (MTBE) is a persistent pollutant of surface and groundwater, and the reasons for its low biodegradability are poorly documented. Using one of the rare bacterial strains able to grow in the presence of MTBE, Mycobacterium austroafricanum IFP 2012, the protein profiles of crude extracts after growth in the presence of MTBE and glucose were compared by SDS-PAGE. Ten proteins with molecular masses of 67, 64, 63, 55, 50, 27, 24, 17, 14 and 11 kDa were induced after growth in the presence of MTBE. Partial amino acid sequences of N-terminal and internal peptide fragments of th

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14

Kimura, T., Mohammad A. Khan, Masakazu Ishii, et al. "Enthalpic changes on mixing two couples of S- and R-enantiomers of benzyl-(1-phenyl-ethyl)-amine, 1-phenylethylamine, 1-phenyl-ethanol, butyric acid oxiranylmethyl ester, 4-methyl-[1,3]dioxolan-2-one, 2-chloro-methyloxirane and 3-hydroxyisobutyric acid methyl ester at T=298.15K." Journal of Chemical Thermodynamics 38, no. 8 (2006): 1042–48. http://dx.doi.org/10.1016/j.jct.2005.10.019.

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15

Domingo, L. R., J. Andrés, V. Moliner, and V. S. Safont. "Theoretical Study of the Gas Phase Decomposition of Glycolic, Lactic, and 2-Hydroxyisobutyric Acids." Journal of the American Chemical Society 119, no. 27 (1997): 6415–22. http://dx.doi.org/10.1021/ja962857v.

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16

Le�n, Rosa, Francesco Molinari, Duarte M?F Prazeres, and Joaquim M?S Cabral. "Organic media selection for the extraction of ?-hydroxyisobutyric acid produced by microbial biotransformation." Journal of Chemical Technology & Biotechnology 75, no. 7 (2000): 617–24. http://dx.doi.org/10.1002/1097-4660(200007)75:7<617::aid-jctb110>3.0.co;2-1.

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17

Pollitt, R. J., A. Green та R. Smith. "Excessive excretion of β-alanine and of 3-hydroxypropionic,R- andS-3-aminoisobutyric,R- andS-3-hydroxyisobutyric andS-2-(hydroxymethyl)butyric acids probably due to a defect in the metabolism of the corresponding malonic semialdehydes". Journal of Inherited Metabolic Disease 8, № 2 (1985): 75–79. http://dx.doi.org/10.1007/bf01801669.

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18

Whitehead, Anna, Fynn N. Krause, Amy Moran, et al. "Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis." Nature Communications 12, no. 1 (2021). http://dx.doi.org/10.1038/s41467-021-22272-3.

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AbstractBrown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid, 5-oxoproline, and β-hydroxyisobutyric acid as small molecule metabokines synthesized in browning adipocytes and secreted via monocarboxylate transporters. 3-methyl-2-oxovaleric acid, 5-oxoproline and β-hydroxyisobutyric acid induce a brown adipocyte-specific phenotype in white adipocytes an

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19

Schifano, Emily, Giorgia Conta, Adele Preziosi, et al. "2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans." Frontiers in Molecular Biosciences 9 (November 23, 2022). http://dx.doi.org/10.3389/fmolb.2022.986022.

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High levels of 2-hydroxyisobutyric acid (2-HIBA) were found in urines of patients with obesity and hepatic steatosis, suggesting a potential involvement of this metabolite in clinical conditions. The gut microbial origin of 2-HIBA was hypothesized, however its actual origin and role in biological processes are still not clear. We investigated how treatment with 2-HIBA affected the physiology of the model organism Caenorhabditis elegans, in both standard and high-glucose diet (HGD) growth conditions, by targeted transcriptomic and metabolomic analyses, Coherent Anti-Stokes Raman Scattering (CAR

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20

Rohde, Maria-Teresa, Sylvi Tischer, Hauke Harms, and Thore Rohwerder. "Production of 2-Hydroxyisobutyric Acid from Methanol by Methylobacterium extorquens AM1 Expressing (R)-3-Hydroxybutyryl Coenzyme A-Isomerizing Enzymes." Applied and Environmental Microbiology 83, no. 3 (2016). http://dx.doi.org/10.1128/aem.02622-16.

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ABSTRACT The biotechnological production of the methyl methacrylate precursor 2-hydroxyisobutyric acid (2-HIBA) via bacterial poly-3-hydroxybutyrate (PHB) overflow metabolism requires suitable (R)-3-hydroxybutyryl coenzyme A (CoA)-specific coenzyme B12-dependent mutases (RCM). Here, we characterized a predicted mutase from Bacillus massiliosenegalensis JC6 as a mesophilic RCM closely related to the thermophilic enzyme previously identified in Kyrpidia tusciae DSM 2912 (M.-T. Weichler et al., Appl Environ Microbiol 81:4564–4572, 2015, https://doi.org/10.1128/AEM.00716-15 ). Using both RCM varia

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21

Przybylski, Denise, Thore Rohwerder, Hauke Harms, and Roland H. Mueller. "Third-generation feed stocks for the clean and sustainable biotechnological production of bulk chemicals: synthesis of 2-hydroxyisobutyric acid." Energy, Sustainability and Society 2, no. 1 (2012). http://dx.doi.org/10.1186/2192-0567-2-11.

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22

Rohwerder, Thore, Maria-Teresa Rohde, Nico Jehmlich, and Jessica Purswani. "Actinobacterial Degradation of 2-Hydroxyisobutyric Acid Proceeds via Acetone and Formyl-CoA by Employing a Thiamine-Dependent Lyase Reaction." Frontiers in Microbiology 11 (April 15, 2020). http://dx.doi.org/10.3389/fmicb.2020.00691.

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23

Zacchia, Miriam, Emanuela Marchese, Marianna Caterino, Margherita Ruoppolo, and Giovambattista Capasso. "P0031AURINE METABOLOMICS: AN EMERGING TOOL FOR DISSECTING BIOLOGICAL ABERRATIONS UNDERLYING RENAL DYSFUNCTION IN BARDET-BIEDL SYNDROME." Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa142.p0031a.

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Abstract Background and Aims Bardet Biedl Syndrome (BBS) is a rare genetic disorder characterized by a wide range of organ dysfunction, including kidney disease. The severity of renal dysfunction is highly variable in this setting, ranging from tubular defects to the end stage renal disease, with poor genotype-phenotype correlation. Proteomics and metabolomics are powerful tools able to contribute to the better understanding of molecular basis of disease conditions. Our previous studies demonstrated that the urinary proteomic pattern of BBS patients differed from that of healthy subjects, with

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24

Mai, Dung Hoang Anh, Thu Thi Nguyen, and Eun Yeol Lee. "The ethylmalonyl-CoA pathway for methane-based biorefineries: a case study of using Methylosinus trichosporium OB3b, an alpha-proteobacterial methanotroph, for producing 2-hydroxyisobutyric acid and 1,3-butanediol from methane." Green Chemistry, 2021. http://dx.doi.org/10.1039/d1gc02866a.

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Through genome-scale metabolic model simulations and transcriptomic analysis the ethylmalonyl-CoA pathway of an alpha-proteobacteria, Methylosinus trichosporium OB3b, was systematically assessed and exploited to produce 2-hydroxybutiric acid and 1,3-butanediol from methane.

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25

Szabo, P. G., A. G. Tasi, X. Gaona, et al. "Uptake of selected organic ligands by hardened cement paste: Studies on proxy ligands for the degradation of polyacrylonitrile and general considerations on the role of different functionalities in the uptake process." Frontiers in Nuclear Engineering 1 (October 5, 2022). http://dx.doi.org/10.3389/fnuen.2022.997398.

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The uptake of α-hydroxyisobutyric acid (HIBA), 3-hydroxybutyric acid (HBA) and glutaric acid (GTA) by hardened cement paste (HCP) in the degradation stage II was investigated at various ligand concentrations (10−7 M ≤ [L]tot ≤ 0.1 M) and solid-to-liquid ratios (0.2 g⋅dm−3 ≤ S:L ≤ 50 g⋅dm−3). These organic ligands were previously identified as representative of the main degradation products of UP2W, a polyacrylonitrile-based material used as filter aid in nuclear power plants, under repository conditions. Sorption experiments were conducted with inactive (HIBA, HBA, GTA) and active (14C-labelle

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26

Lee, Seung-Gu, and Kyung-Seok Ko. "Development of an analytical method for accurate and precise determination of rare earth element concentrations in geological materials using an MC-ICP-MS and group separation." Frontiers in Chemistry 10 (January 12, 2023). http://dx.doi.org/10.3389/fchem.2022.906160.

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The concentration of rare earth elements (REEs) in geological materials including SLRS-6 (natural water certified reference material) and JB1b, JA1, and JG2 (Standard Rock Materials of Geological Survey of Japan) can be used as a tracer to characterize various geochemical processes in earth systems. Particularly, accurate and precise determination of rare earth element concentration in natural waters is difficult due to their extremely low concentration and the interference of polyatomic oxides. In this study, we developed a method for accurate and precise determination of the REE (particularl

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27

Szabo, P. G., A. G. Tasi, X. Gaona, et al. "Uptake of Ni(II), Eu(III) and Pu(III/IV) by Hardened Cement Paste in the Presence of Proxy Ligands for the Degradation of Polyacrylonitrile." Frontiers in Nuclear Engineering 2 (February 13, 2023). http://dx.doi.org/10.3389/fnuen.2023.1117413.

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The uptake of 63Ni(II), 152Eu(III) and 242Pu(III/IV) by hardened cement paste (HCP, CEM I) in the degradation stage II (pH ≈ 12.5 [Ca] ≈ 0.02 M) was investigated in the absence and presence of α-hydroxyisobutyric, 3-hydroxybutyric and glutaric acids. These organic ligands were previously identified as proxies for the degradation products of UP2W (a polyacrylonitrile-based material used as filter aid in nuclear power plants) under repository conditions. Sorption experiments were conducted with various ligand concentrations (10−4 M ≤ [L]tot ≤ 0.1 M) and solid-to-liquid ratios (0.5 g⋅dm–3 ≤ S:L ≤

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28

Irajizad, Ehsan, Chae Y. Han, Joseph Celestino, et al. "A blood-based metabolite panel for distinguishing ovarian cancer from benign pelvic masses." Clinical Cancer Research, August 29, 2022. http://dx.doi.org/10.1158/1078-0432.ccr-22-1113.

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Abstract Purpose: To assess the contributions of circulating metabolites for improving upon the performance of the Risk of Ovarian Malignancy Algorithm (ROMA) for risk prediction of ovarian cancer (OvCa) among women with ovarian cysts. Experimental Design: Metabolomic profiling was performed on an initial set of sera from 101 serous and non-serous OvCa cases and 134 individuals with benign pelvic masses (BPM). Using a deep learning model, a panel consisting of seven cancer-related metabolites (diacetylspermine, diacetylspermidine, N-(3-acetamidopropyl)pyrrolidin-2-one, N-acetylneuraminate, N-a

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