Relevant bibliographies by topics / 2 Indolizine Derivatives

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  2. Dissertations / Theses

Academic literature on the topic '2 Indolizine Derivatives'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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Journal articles on the topic "2 Indolizine Derivatives"

1

Sekgota, Khethobole C., Michelle Isaacs, Heinrich C. Hoppe, et al. "Propylphosphonic acid anhydride–mediated amidation of Morita–Baylis–Hillman–derived indolizine-2-carboxylic acids." Journal of Chemical Research 45, no. 7-8 (2021): 674–78. http://dx.doi.org/10.1177/1747519820987156.

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Propylphosphonic acid anhydride has been successfully used as a coupling agent in the synthesis of a series of indolizine-2-carboxamido derivatives from indolizine-2-carboxylic acid and its 3-acetylated analogue. The acid substrates were obtained by saponification of the corresponding methyl esters produced, in turn, selectively and efficiently, by time-controlled cyclisation of a single Morita–Baylis–Hillman adduct. Various amino and hydrazino compounds with medicinal potential have been used to prepare indolizine-2-carboxamido and hydrazido derivatives.
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2

Liu, Ren-Rong, Zheng-Yi Cai, Chuan-Jun Lu, et al. "Indolizine synthesis via Cu-catalyzed cyclization of 2-(2-enynyl)pyridines with nucleophiles." Organic Chemistry Frontiers 2, no. 3 (2015): 226–30. http://dx.doi.org/10.1039/c4qo00336e.

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3

Dong, Shanliang, Jingjing Huang, Hongkai Sha, Lihua Qiu, Wenhao Hu, and Xinfang Xu. "Copper-catalyzed formal [1 + 2 + 2]-annulation of alkyne-tethered diazoacetates and pyridines: access to polycyclic indolizines." Organic & Biomolecular Chemistry 18, no. 10 (2020): 1926–32. http://dx.doi.org/10.1039/d0ob00222d.

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A copper-catalyzed formal [1 + 2 + 2]-annulation of alkyne-tethered diazo compounds with pyridines, which affords polycyclic fused indolizine derivatives with broad substrate generality, has been reported.
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4

Su, Kexin, Xin Guo, Liangwei Zhu, Yafeng Liu, Yixuan Lu, and Baohua Chen. "Indolizine synthesis via radical cyclization and demethylation of sulfoxonium ylides and 2-(pyridin-2-yl)acetate derivatives." Organic Chemistry Frontiers 8, no. 15 (2021): 4177–82. http://dx.doi.org/10.1039/d1qo00550b.

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A novel radical cross-coupling/cyclization of 2-(pyridin-2-yl)acetate derivatives and sulfoxonium ylides is developed, which provides a straightforward access to structurally diverse methylthio-substituted indolizine.
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5

López, Luis A., and Javier González. "Copper(i)-carbenes as key intermediates in the [3 + 2]-cyclization of pyridine derivatives with alkenyldiazoacetates: a computational study." Organic & Biomolecular Chemistry 17, no. 3 (2019): 646–54. http://dx.doi.org/10.1039/c8ob02676a.

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This work reports a computational study of the copper(i)-catalyzed regioselective synthesis of indolizine derivatives through the [3 + 2]-cyclization reaction of vinyldiazo acetates and pyridine derivatives.
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6

Dohmen, Christoph, Heiko Ihmels, Rouven Kreienmeier, and Brian O. Patrick. "Synthesis of a crystallochromic indolizine dye by a base- and catalyst-free photochemical route." Chemical Communications 55, no. 74 (2019): 11071–74. http://dx.doi.org/10.1039/c9cc04730a.

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Irradiation of 2-benzoyl-N-benzylpyridinium derivatives and dimethyl acetylene dicarboxylate resulted in the formation of inolizine derivatives, one which was found to be the first example of a crystallochromic indolizine.
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7

Dawood, Kamal M., Eman A. Ragab, and Sanaa N. Mohamed. "Synthesis of Some New Indolizine and Pyrrolo[1,2-a]quinoline Derivatives via Nitrogen Ylides." Zeitschrift für Naturforschung B 64, no. 4 (2009): 434–38. http://dx.doi.org/10.1515/znb-2009-0413.

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Pyridine and quinoline react with 3-bromoacetyl-1,5-diphenyl-1H-pyrazole-4-carbonitrile (2) in dry benzene to give the corresponding pyridinium and quinolinium salts 3 and 9. The latter salts undergo [3+2] 1,3-dipolar cycloaddition with some acetylene and ethylene derivatives to give the corresponding indolizine and pyrrolo[1,2-a]quinoline derivatives
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8

Atar, Amol Balu, Jongmin Kang, and Arvind H. Jadhav. "A [bmim]Cl-promoted domino protocol using an isocyanide-based [4+1]-cycloaddition reaction for the synthesis of diversely functionalized 3-alkylamino-2-alkyl/aryl/hetero-aryl indolizine-1-carbonitriles under solvent-free conditions." New Journal of Chemistry 44, no. 8 (2020): 3241–48. http://dx.doi.org/10.1039/c9nj05738b.

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A room temperature-based ionic liquid [bmim]Cl-catalyzed multicomponent coupling strategy for the synthesis of 3-alkylamino-2-alkyl/aryl/hetero-aryl indolizine-1-carbonitrile derivatives under mild conditions is shown.
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9

Lu, Chuan-Jun, Xin Yu, Yu-Ting Chen, Qing-Bao Song, and Hong Wang. "Indolizine synthesis via copper-catalyzed cyclization of gem-difluoroalkenes and 2-(pyridin-2-yl)acetate derivatives." Organic Chemistry Frontiers 7, no. 16 (2020): 2313–18. http://dx.doi.org/10.1039/d0qo00553c.

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10

Belguedj, Roumaissa, Sofiane Bouacida, Hocine Merazig, Ali Belfaitah, and Abdelmalek Bouraiou. "1-(2′-Benzimidazolylmethyl)-pyridinium ylide in the one-pot synthesis of indolizine and benzimidazo[1,2-a]pyridine derivatives." Zeitschrift für Naturforschung B 70, no. 8 (2015): 555–61. http://dx.doi.org/10.1515/znb-2015-0016.

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AbstractFour indolizine derivatives were obtained via 1,3-dipolar cycloaddition reaction of 1-(2′-benzimidazolylmethyl)pyridinium ylide with various electron-deficient alkynes. The reaction of this pyridinium N-ylide with dimethyl maleate gave an unexpected methyl 1-oxo-benzimidazo[1,2-a]pyridine-3-carboxylate. The structures of all reported compounds have been examined by X-ray crystallography and NMR spectroscopy.
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Dissertations / Theses on the topic "2 Indolizine Derivatives"

1

Cunha, Saraghina Maria Donato da. "A síntese via Adutos de Morita Baylis Hillman dos derivados 2-Indolizina em micro-ondas: novos potenciais moduladores de canais iônicos." Universidade Federal da Paraí­ba, 2013. http://tede.biblioteca.ufpb.br:8080/handle/tede/7104.

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Made available in DSpace on 2015-05-14T13:21:25Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 2013817 bytes, checksum: 3393f3576fe03283e4e7fd592df689eb (MD5) Previous issue date: 2013-03-05<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>This work presents microwave irradiation promoting synthetic studies that producing by the first time indolizine-2-carbonitrile (1) and indolizine-2-carboxylate (2) in good to high yields (70% and 81%, respectively) in one step from Morita-Baylis- Hillman adducts (MBHA) 2-(hydroxy(pyridin-2-yl)methyl)acrylonitrile (10) and met
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2

Murali, Dheeptha. "Chemistry of quinoline-2-carbaldehyde derivatives with malononitrile and formation of indolizines." 2011. http://liblink.bsu.edu/uhtbin/catkey/1657738.

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The quinoline-5,8-diones are an important class of compounds with a wide spectrum of biological activites such as antibacterial, antiasthmatic, antifungal, antitumour and antiparasitic agents. Over the past three decades many variously substituted derivatives of quinoline-5,8-diones have been synthesized and reported. The majority of them dealt with the chemistry of C-6 and/or C-7 substituted quinolinediones and were related to Lavendamycin. Our lab has developed several procedures for the condensation (Knoevenagel) and reduction of aldehydes and ketones with malononitrile. When this reductive
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