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Journal articles on the topic '2-methylquinoxaline'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Thiruvalluvar, A., M. Subramanyam, R. J. Butcher, A. V. Adhikari, and S. Wagle. "2-Chloro-3-methylquinoxaline." Acta Crystallographica Section E Structure Reports Online 63, no. 12 (2007): o4534. http://dx.doi.org/10.1107/s1600536807054475.

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2

Goswami, Shyamaprosad, Annada C. Maity, Santiago García-Granda, and Laura Torre-Fernández. "3-Methylquinoxaline-2-carbonitrile." Acta Crystallographica Section E Structure Reports Online 63, no. 4 (2007): o1741—o1742. http://dx.doi.org/10.1107/s1600536807010537.

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3

Li, Jian-Ye, Tao Sun, Ai-You Hao, Hongwei Qiao, and Feifei Xin. "2-Isopropyl-3-methylquinoxaline 1,4-dioxide." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o1906. http://dx.doi.org/10.1107/s1600536810023706.

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4

Pejin, Jelena, Olgica Grujic, Nikola Marjanovic, Djura Vujic, and Suncica Kocic-Tanackov. "Determina tion of diacetyl and 2,3-pentanedione in beer by gc/ms using solid-phase extraction columns." Acta Periodica Technologica, no. 33 (2002): 45–54. http://dx.doi.org/10.2298/apt0233045p.

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A new GC/MS method for the determination of diacetyl and 2,3-pentanedione was investigated. Diacetyl and 2,3-pentanedione were derivatized with 1,2-diaminobenzene to form 2,3-dimetylquinoxaline and 2-ethyl-3-methylquinoxaline. respectively. The amounts of formed 2.3-dimetylqu:inoxaline and 2-ethyl-3,.methylquinoxaline were proportional to the concentrations of diacetyl and 2,3-penianedione present in the sample. 2,3-Dimetylquinoxaline and 2-ethyl-3-methylquinoxaline were extracted by solid-phase extraction (SPE) columns and determined by gas chromatography using a mass selective detector. This

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5

Nováček, Libor, and Miloslav Nechvátal. "Partial reduction of quinoxaline 1,4-dioxide derivatives with L-ascorbic acid." Collection of Czechoslovak Chemical Communications 53, no. 6 (1988): 1302–6. http://dx.doi.org/10.1135/cccc19881302.

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Partial reduction of quinoxaline 1,4-dioxide derivatives with L-ascorbic acid has been elaborated. Quinoxaline 1,4-dioxide, 2,3-dimethylquinoxaline 1,4-dioxide, 2-methylquinoxaline 1,4-dioxide and 2-(N-(2-hydroxyethyl)carbamoyl)-3-methylquinoxaline 1,4-dioxide afforded monoxides. In the monomethyl derivatives the more distant N-O bond is reduced. In addition to the monoxide, quinoxaline 1,4-dioxide afforded small amount of quinoxaline. Structures of all the compounds have been confirmed by 1H and 13C NMR spectroscopy.

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6

Wong, John W., Harry A. Watson,, James F. Bouressa, et al. "Biocatalytic Oxidation of 2-Methylquinoxaline to 2-Quinoxalinecarboxylic Acid." Organic Process Research & Development 6, no. 4 (2002): 477–81. http://dx.doi.org/10.1021/op025501e.

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7

Li, Yubo, Wenfeng Zhou, Jinli Wang, Haixiang Gao, and Zhiqiang Zhou. "3-Methylquinoxaline-2-carboxylic acid 4-oxide monohydrate." Acta Crystallographica Section E Structure Reports Online 66, no. 7 (2010): o1801. http://dx.doi.org/10.1107/s160053681002266x.

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8

Allan, J. R., A. D. Paton, A. J. Blake, and K. Turvey. "Structure of dichloro(2-methylquinoxaline-N4)mercury(II)." Acta Crystallographica Section C Crystal Structure Communications 45, no. 9 (1989): 1422–24. http://dx.doi.org/10.1107/s0108270189005366.

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9

Postnikov, L. S., I. V. Korovina, A. D. Kagarlitskii, and L. A. Krichevskii. "Oxidative ammonolysis of 2-methylquinoxaline on vanadium-titanium oxide catalyst." Russian Journal of Applied Chemistry 81, no. 2 (2008): 320–22. http://dx.doi.org/10.1134/s1070427208020316.

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10

Matoba, Katsuhide, Takashi Terada, Masaru Sugiura, and Takao Yamazaki. "Reactions of 2-Acetyl-3-methylquinoxaline 1,4-Dioxide and Its Derivatives." HETEROCYCLES 26, no. 1 (1987): 55. http://dx.doi.org/10.3987/r-1987-01-0055.

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11

Ribeiro da Silva, M. A. V., M. A. R. Matos, C. M. A. Rio, M. S. Miranda, and V. M. F. Morais. "Thermochemical and Theoretical Studies of 2-Hydroxyquinoxaline, 2,3-Dihydroxyquinoxaline, and 2-Hydroxy-3-methylquinoxaline." Journal of Physical Chemistry A 104, no. 28 (2000): 6644–48. http://dx.doi.org/10.1021/jp000694y.

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12

Bianchini, Claudio, Pierluigi Barbaro, Giancarlo Scapacci, Erica Farnetti, and Mauro Graziani. "Enantioselective Hydrogenation of 2-Methylquinoxaline to (−)-(2S)-2-Methyl-1,2,3,4-tetrahydroquinoxaline by Iridium Catalysis." Organometallics 17, no. 15 (1998): 3308–10. http://dx.doi.org/10.1021/om980219a.

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13

Aggarwal, Ranjana, Garima Sumran, Rajiv Kumar, and Shiv P. Singh. "Reaction of 2-hydrazino-3-methylquinoxaline with aryl-1,3-diketones: A structural reinvestigation." Arkivoc 2007, no. 15 (2007): 292–302. http://dx.doi.org/10.3998/ark.5550190.0008.f28.

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14

Cordeiro, Carlos, and Ana Ponces Freire. "Methylglyoxal Assay in Cells as 2-Methylquinoxaline Using 1,2-Diaminobenzene as Derivatizing Reagent." Analytical Biochemistry 234, no. 2 (1996): 221–24. http://dx.doi.org/10.1006/abio.1996.0076.

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15

Singh, D. C. P., S. R. Hashim, and R. G. Singhal. "Synthesis and Antimicrobial Activity ofSome New Thioether Derivatives of Quinoxaline." E-Journal of Chemistry 8, no. 2 (2011): 635–42. http://dx.doi.org/10.1155/2011/482831.

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2-Chloro-3-methylquinoxaline was selected as nucleus around which the molecular manipulations were carried out to get new compounds expected to possess better anti microbial activity. Various quinoxaline derivatives have been synthesized by replacing the chlorine at C-2 with a thioether linkage, which in turn attached to 2-(N-(substituted phenyl)acetamides. The synthesized compounds (5) were tested for their antimicrobial activity. Compounds 5b, 5c, 5d and 5i were found most active (comparable to the standard antibacterial Ciprofloxacin) amongst them. The structure of the compounds was confirm

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16

Chen, Wulian, Chaomin Zhao, and Xiaojun Deng. "Synthesis of deuterium-labeled 2-quinoxalinecarboxylic acid and 3-methylquinoxaline-2-carboxylic acid from deuterium aniline." Journal of Labelled Compounds and Radiopharmaceuticals 61, no. 14 (2018): 1043–47. http://dx.doi.org/10.1002/jlcr.3679.

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17

Wiedling, Sten. "ANTIBACTERIAL EFFECTS OF IODININ, 2-METHYLQUINOXALINE DI-N-OXIDE AND 2,6-DIMETHOXYBENZOQUINONE IN VITRO." Acta Pathologica Microbiologica Scandinavica 22, no. 4 (2009): 379–91. http://dx.doi.org/10.1111/j.1699-0463.1945.tb04073.x.

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18

Zhang, Keyu, Manman Ban, Zhanzhong Zhao, et al. "Cytotoxicity and genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic acid (MQCA) in human hepatocytes." Research in Veterinary Science 93, no. 3 (2012): 1393–401. http://dx.doi.org/10.1016/j.rvsc.2012.06.012.

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19

Aggarwal, Ranjana, Rajiv Kumar та Shiv P. Singh. "Some novel observations on the reaction of 2-hydrazino-3-methylquinoxaline with trifluoromethyl-β-diketones". Journal of Fluorine Chemistry 130, № 10 (2009): 886–93. http://dx.doi.org/10.1016/j.jfluchem.2009.06.021.

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20

Ancizu, Saioa, Elsa Moreno, Beatriz Solano, et al. "New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents." Bioorganic & Medicinal Chemistry 18, no. 7 (2010): 2713–19. http://dx.doi.org/10.1016/j.bmc.2010.02.024.

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21

Venu Gopal, D., and M. Subrahmanyam. "Single-step synthesis of 2-methylquinoxaline from 1,2-phenylenediamine and 1,2-propanediol over modified HY zeolites." Catalysis Communications 2, no. 6-7 (2001): 219–23. http://dx.doi.org/10.1016/s1566-7367(01)00037-1.

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22

Das, Umashankar, Hari N. Pati, Atulya K. Panda, et al. "2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance." Bioorganic & Medicinal Chemistry 17, no. 11 (2009): 3909–15. http://dx.doi.org/10.1016/j.bmc.2009.04.021.

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23

Carta, Antonio, Sandra Piras, Giuseppe Paglietti, et al. "2(3)-Aryl-thio(oxy)-methylquinoxaline Derivatives: A New Class of P-Glycoprotein-Mediated Drug Efflux Inhibitors." Medicinal Chemistry 4, no. 3 (2008): 194–205. http://dx.doi.org/10.2174/157340608784325197.

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24

Benallal, R., H. Bougharraf, A. Aamoum, et al. "Experimental (X-ray Diffraction, UV–Vis Spectroscopy) and DFT Studies of 1-Ethyl-3-methylquinoxaline-2-thione." Russian Journal of Physical Chemistry A 94, no. 2 (2020): 360–69. http://dx.doi.org/10.1134/s0036024420020053.

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25

Ohmori, Shinji, Mie Mori, Michi Kawase, and Seiji Tsuboi. "Determination of methylglyoxal as 2-methylquinoxaline by high-performance liquid chromatography and its application to biological samples." Journal of Chromatography B: Biomedical Sciences and Applications 414 (January 1987): 149–55. http://dx.doi.org/10.1016/0378-4347(87)80033-6.

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26

MONDIEIG, D., Ph NÉGRIER, J. M. LÉGER, et al. "Crystal Structure of 2-S-(1′-Deoxy-2′,3′:4′,5′-di-O-isopropylidene-D,L-xylit-1′-ylthio)-3-methylquinoxaline." X-ray Structure Analysis Online 26 (2010): 1–2. http://dx.doi.org/10.2116/xraystruct.26.1.

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27

MONDIEIG, D., Ph NÉGRIER, J. M. LÉGER та ін. "Crystal Structure of 2-S-(6′-Deoxy-1′,2′:3′,4′-di-O-isopropylidene-α-D-galactopyranos-6′-ylthio)-3-methylquinoxaline". Analytical Sciences: X-ray Structure Analysis Online 24 (2008): x291—x292. http://dx.doi.org/10.2116/analscix.24.x291.

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28

Allan, J. R., A. D. Paton, K. Turvey, D. L. Gerrard, and S. Hoey. "Thermal, structural and electrical studies of the chloro complexes of cobalt, nickel, copper and zinc with 2-methylquinoxaline." Thermochimica Acta 145 (June 1989): 291–300. http://dx.doi.org/10.1016/0040-6031(89)85149-4.

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29

Allan, J. R., A. D. Paton, and K. Turvey. "Preparation, structural characterisation, and thermal and electrical studies of complexes of zinc, cadmium and mercury with 2-methylquinoxaline." Thermochimica Acta 191, no. 1 (1991): 211–21. http://dx.doi.org/10.1016/0040-6031(91)87251-q.

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30

Saoudi, Besma, Abderrahmane Teniou, Adbelmadjid Debache, Thierry Roisnel, Jean-François Soulé, and Henri Doucet. "Cyclisation reaction between 3-methylquinoxaline-2-thione and benzaldehydes into 3-benzyl-2-aryl-thieno[2,3-b]quinoxaline promoted by Brønsted acids." Comptes Rendus Chimie 18, no. 8 (2015): 808–15. http://dx.doi.org/10.1016/j.crci.2015.06.003.

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31

Gomes, José R. B., Emanuel A. Sousa, Jorge M. Gonçalves, et al. "Energetic and structural characterization of 2-R-3-methylquinoxaline-1,4-dioxides (R = benzoyl ortert-butoxycarbonyl): experimental and computational studies." Journal of Physical Organic Chemistry 20, no. 7 (2007): 491–98. http://dx.doi.org/10.1002/poc.1184.

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32

Zha, Yu-bing, Chun-liang Yang, Yi-zhi Lv, et al. "Determination of Residues of two Aminoglycoside antibiotics and five Quinololine antibiotics and Their Metabolites in Penaeus vannamei by Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry." E3S Web of Conferences 213 (2020): 01033. http://dx.doi.org/10.1051/e3sconf/202021301033.

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An ultra performance liquid chromatography – electrospray ionization triple-quadruple tandem mass spectrometric(UPLC–ESI MS /MS) method was developed for determining Quinololine antibiotics (Carbadox,, Quinocetone, Mequindox, Olaquindox, Cyadox, Tilmicosin, Tylosin, quinoxaline-2-carboxylic acid, 3-methylquinoxaline-2-carboxylic acid) and aminoglycoside antibiotics(Tilmicosin, Tylosin) residues in Penaeus. vannamei, Samples were extracted with acidified acetonitrile, then cleaned up with hexane. The separation of targets was carried out on a Waters BEH C18 column using acetonitrile and 0. 1% f

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33

Das, Umashankar, Swagatika Das, Brian Bandy, Dennis K. J. Gorecki, and Jonathan R. Dimmock. "E-2-[3-(3,4-Dichlorophenyl)-1-oxo-2-propenyl]-3-methylquinoxaline-1,4-dioxide: A lead antitubercular agent which alters mitochondrial respiration in rat liver." European Journal of Medicinal Chemistry 45, no. 10 (2010): 4682–86. http://dx.doi.org/10.1016/j.ejmech.2010.07.030.

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34

Bartczak, Tadeusz J., Zdzis?aw Galdecki, Wojciech Wolf, and Thomas C. W. Mak. "Studies of substituted quinoxaline-di-N-oxides. Part 1. Crystal structure and molecular conformation of 2-[N-(2-hydroxyethyl)carboxamide]-3-methylquinoxaline 1,4-dioxide." Journal of Crystallographic and Spectroscopic Research 18, no. 2 (1988): 165–74. http://dx.doi.org/10.1007/bf01181908.

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35

Carta, Antonio, Mario Loriga, Giuseppe Paglietti, et al. "Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides." European Journal of Medicinal Chemistry 39, no. 2 (2004): 195–203. http://dx.doi.org/10.1016/j.ejmech.2003.11.008.

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36

Alanazi, Mohammed M., Ibrahim H. Eissa, Nawaf A. Alsaif, et al. "Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers." Journal of Enzyme Inhibition and Medicinal Chemistry 36, no. 1 (2021): 1760–82. http://dx.doi.org/10.1080/14756366.2021.1956488.

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37

Brunner, Henri, and Sabine Rosenboem. "ChemInform Abstract: Enantioselective Catalyses. Part 135. Stereoselective Hydrogenation of Folic Acid and 2-Methylquinoxaline with Optically Active Rhodium(I)-Phosphane Complexes." ChemInform 32, no. 16 (2001): no. http://dx.doi.org/10.1002/chin.200116158.

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38

Vicente, Esther, Raquel Villar, Asunción Burguete, et al. "Efficacy of Quinoxaline-2-Carboxylate 1,4-Di-N-Oxide Derivatives in Experimental Tuberculosis." Antimicrobial Agents and Chemotherapy 52, no. 9 (2008): 3321–26. http://dx.doi.org/10.1128/aac.00379-08.

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ABSTRACT This study extends earlier reports regarding the in vitro efficacies of the 1,4-di-N-oxide quinoxaline derivatives against Mycobacterium tuberculosis and has led to the discovery of a derivative with in vivo efficacy in the mouse model of tuberculosis. Quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives were tested in vitro against a broad panel of single-drug-resistant M. tuberculosis strains. The susceptibilities of these strains to some compounds were comparable to those of strain H37Rv, as indicated by the ratios of MICs for resistant and nonresistant strains, supporting the prem

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39

Andrews, Michael, Rebecca H. Laye, Lindsay P. Harding, and Simon J. A. Pope. "Quinoxaline sensitised lanthanide ion luminescence: Syntheses, spectroscopy and X-ray crystal structure of Na{1,4,7-tris[(N-diethyl)carbamoylmethyl]-1,4,7,10-tetraazacyclododecane-10-(2-methylquinoxaline)}I3 C7H8." Polyhedron 27, no. 11 (2008): 2365–71. http://dx.doi.org/10.1016/j.poly.2008.04.010.

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40

McLellan, Antony C., and Paul J. Thornalley. "Synthesis and chromatography of 1,2-diamino-4,5-dimethoxybenzene, 6,7-dimethoxy-2-methylquinoxaline and 6,7-dimethoxy-2,3-dimethylquinoxaline for use in a liquid chromatographic fluorimetric assay of methylglyoxal." Analytica Chimica Acta 263, no. 1-2 (1992): 137–42. http://dx.doi.org/10.1016/0003-2670(92)85435-9.

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41

Vicente, José, M. Cristina Lagunas, Elke Bleuel, and M. Carmen Ramı́rez de Arellano. "5-Methylquinoxaline as a versatile mono-, bi- and tridentate ligand in Palladium(II) chemistry. Crystal structures of trans-[Pd(OAc)2(N1-C8H5N2Me-5)2] and [Pd(OAc)(C,N4-CH2C8H5N2-5)(PPh3)]." Journal of Organometallic Chemistry 648, no. 1-2 (2002): 62–71. http://dx.doi.org/10.1016/s0022-328x(01)01394-8.

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42

Ahamed, J. Irshad, G. R. Ramkumaar, P. Kamalarajan, et al. "Novel quinoxaline derivatives of 2, 3-diphenylquinoxaline-6-carbaldehyde and 4, 4′-(6-methylquinoxaline-2,3-diyl)bis(N,N-diphenylaniline): Synthesis, structural, DFT-computational, molecular docking, antibacterial, antioxidant, and anticancer studies." Journal of Molecular Structure 1248 (January 2022): 131418. http://dx.doi.org/10.1016/j.molstruc.2021.131418.

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43

Ramli, Youssef, Ahmed Moussaif, Hafid Zouihri, Houda Bourichi, and El Mokhtar Essassi. "N′-(3-Methylquinoxalin-2-yl)-N′-phenylbenzohydrazide." Acta Crystallographica Section E Structure Reports Online 67, no. 6 (2011): o1374. http://dx.doi.org/10.1107/s160053681101703x.

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44

Ramli, Youssef, Ahmed Moussaif, Hafid Zouihri, Saïd Lazar, and E. M. Essassi. "1-Benzyl-3-methylquinoxalin-2(1H)-one." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o1922. http://dx.doi.org/10.1107/s1600536810025614.

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45

Benzeid, Hanane, Laure Vendier, Youssef Ramli, Bernard Garrigues, and El Mokhtar Essassi. "1-Ethyl-3-methylquinoxalin-2(1H)-one." Acta Crystallographica Section E Structure Reports Online 64, no. 11 (2008): o2234. http://dx.doi.org/10.1107/s1600536808033989.

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46

Ahoya, Caleb Anothane, Rachid Bouhfid, Ballo Daouda, El Mokhtar Essassi, and Lahcen El Ammari. "3-[2-(3-Methylquinoxalin-2-yloxy)ethyl]-1,3-oxazolidin-2-one." Acta Crystallographica Section E Structure Reports Online 66, no. 5 (2010): o1050. http://dx.doi.org/10.1107/s1600536810012687.

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47

Al-Jibouri, Mahmoud, and Saad Hasun. "Synthesis, Characterization and Biological Activity of Chromium(III), Manganese(II), Cobalt(II), Nickel(II), Copper(II) and Zinc(II) Complexes with New Schiff Base Derived from 6-methylquinoxaline-2, 3(1H,4H)-dione and Diethylenetriamine." International Research Journal of Pure and Applied Chemistry 6, no. 4 (2015): 147–59. http://dx.doi.org/10.9734/irjpac/2015/14964.

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48

Gryczyński, Z., and A. Kawski. "Substituent Effects on the Luminescence of 2-Substituted 3-Methylquinoxalines in Poly (Vinyl Alcohol) Films*." Zeitschrift für Naturforschung A 46, no. 4 (1991): 304–6. http://dx.doi.org/10.1515/zna-1991-0402.

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Abstract The effect of 2-substitutions (NH2 . O, CH3O, CI. Br) in 3-methylquinoxalines on the fluorescence and phosphorescence band position and intensity at 293 K, and the temperature dependence of their fluorescence and phosphorescence quantum yields were investigated in polyvinyl alcohol) films

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49

Makino, Kenji, Gozyo Sakata, and Katsushi Morimoto. "Synthesis of Novel 6-Substitutued 2-Chloro-3-methylquinoxalines." HETEROCYCLES 23, no. 8 (1985): 2069. http://dx.doi.org/10.3987/r-1985-08-2069.

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50

Aloui, Sana, Maria Daoudi, Najib Ben Larbi, Taibi Ben Hadda, and Helen Stoeckli-Evans. "3-Hydroxy-3-methyl-4-(3-methylquinoxalin-2-yl)butan-2-one." Acta Crystallographica Section E Structure Reports Online 63, no. 12 (2007): o4930. http://dx.doi.org/10.1107/s1600536807062289.

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