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Journal articles on the topic '2012 g-945'

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Published: 25 July 2024
Last updated: 19 July 2025

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1

Chen, Xue-Gang, and Shinya Fujita. "On diameter and inverse degree of chemical graphs." Applicable Analysis and Discrete Mathematics 7, no. 1 (2013): 83–93. http://dx.doi.org/10.2298/aadm121129022c.

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The inverse degree r(G) of a finite graph G = (V,E) is defined as r(G) = ?v?V 1/d(v), where d(v) is the degree of vertex v. In Discrete Math. 310 (2010), 940-946, Mukwembi posed the following conjecture: Let G be a connected chemical graph with diameter diam(G) and inverse degree r(G). Then diam(G) ? 12/5 r(G) + O(1). In this paper, we settle the conjecture affirmatively.
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2

Kadudula, Prasuna, and Prameela Devi Yalavarthy. "Evaluation of antioxidant activity of the root and leaf extracts of Hemidesmus indicus." Biolife 5, no. 1 (2022): 123–26. https://doi.org/10.5281/zenodo.7360853.

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<strong>ABSTRACT</strong> Free radicals or highly reactive oxygen species are capable of inducing oxidative damage to human body. Antioxidants are the compounds which terminate the attack of reactive species and reduce the risk of diseases. <em>Hemidesmus indicus</em> is used in treatment of various disorders in humans. The study was conducted to determine the antioxidant properties of<em> Hemidesmus indicus</em> leaf and root extracts in methanol. The antioxidant activity of this medicinal plant was evaluated by measuring reducing ability, free radical scavenging activity by DPPH and ABTS.&nbsp; <em>Hemidesmus indicus </em>roots and leaves exhibited significant antioxidant values. The methanolic crude extracts of whole leaf powder of <em>Hemidesmus indicus</em> exhibited significantly higher antioxidant activity than the root of <em>Hemidesmus indicus</em>. It can be concluded from the study that <em>Hemidesmus indicus</em> can be used in treatment of disorders caused by free radical damage. <strong>Key Words:</strong> <em>Hemieismus indicus</em> DPPH, free radical scavenging activity, antioxidant activity, reducing ability. <strong>REFERENCES</strong> Austin, M Jagadeesan, G Shanthi. Pharmacognostical studies on the root varieties of <em>Hemidesmus indicus </em>R. Br. J. Swamy Bot. Club. 2002; 19: 37-43 Bhuiyan MAR., Hoque MZ., Hossain SJ. Free Radical Scavenging Activities of Zizyphus mauritiana. World J. Agr. Sci.2009; 5: 318-322. Chandrashekar A: Antioxidant and <em>in vivo</em> anti-hyperglycemic activity of <em>Muntingiacalabura</em>leaves extracts, Der Lettre, 2013, 5 (3):427-435 Cox SD, KC Jayasinge, J L Markham. Antioxidant activity in Australian native sarsaparilla (<em>Smilax glyciphylla</em>). J Ethnopharmacol. 2005; 101: 162-68. Duh PD., Du PC., Yen GC. Action of methanolic extract of mung beans hulls as inhibitors of lipid peroxidation and non-lipid oxidative damage. Food Chem. Toxicol. 1999; 37: 1055-1061. G.K. Jayaprakash, R.P. Singh, K.K. Sakariah, Antioxidant activity of grape seed extracts on peroxidation models <em>in vitro</em>, J. Agric. Food Chem. 55 (2001) 1018 K. Shimada, K. Fujikawa, K. Yahara, T. Nakamura, Antioxidative properties of xanthan on the anti-oxidation of soybean oil in cyclodextrin emulsion, J. Agric. Food Chem. 40 (1992) 945&ndash;948. Koleva II., Van Beek TA., Linssen JPH., de G root A., Evstatieva LN. Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochem. Anal. 2002; 13: 8-17. Longman O. Indian Medicinal Plants (A Compendium of 500 Species) Vol 3. Reprint edition. 1996. p. 141-145. Meir S., Kanner J., Akiri B., Hada SP. Determination and involvement of aqueous reducing compounds in oxidative defense system of various senescing leaf. J. Agri. Food chem. 1995; 43: 1813-1819. Okwu DE: Evaluation of the chemical composition of indigenous species and flavouring agents. Global J Pure ApplSci, 2001; 7(3): 455-459. R.J. Ruch, S.J. Cheng, J.E. Klaunig, Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea, Carcinogenesis 10 (1989) 1003&ndash;1008. Rao MS., Raman MV. Biochemical systematic and Ecology. 2004; 32:447-448 Roy H., Burdon. Free Radical Damage and its control, Elsevier Science B.V. Netherlands.1994, pp 125. Saeed N, Khan MR and Shabbir M: Antioxidant activity, total phenolic and flavonoid contents of whole plant extracts of TorilisleptophyllaL. BMC Complement Altern Med,2012; 12; 221 Tapiero H, Tew KD, Nguyen Ba G and Math&eacute; G: Polyphenols: do they play a role in prevention of human pathologies? Biomed Pharmacother2002; 56: 200-207. Sateesh Pujari, &amp; Estari Mamidala. (2015). Anti-diabetic activity of Physagulin-F isolated from Physalis angulata fruits. The American Journal of Science and Medical Research, 1(2), 53&ndash;60. https://doi.org/10.5281/zenodo.7352308 Trease GE, Evans WC. Pharmacognosy 16th edition. London: Saunders Elsevier; 2009. p. 309. Wolfenden BS.., Willson RL. Radical-cations as reference chromogens in kinetic studies of one-electron transfer reactions: pulse radiolysis studies &nbsp;of [2,2-azinobis-(3-ethylbenzthiazoline-6- sulphonate)]&nbsp; J. Chem. Soc. Perkin Trans. 1982; 2: 805-812. Yildirim A., Mavi A., Kara AA. Determination of antioxidant and antimicrobial activities of Rumex crispus L. extracts. Journal of Agricultural and Food Chemistry.2001; 9: 4083-4089. Rekka E., Kourounakis PN. Effect of hydroxyethyl rutenosides and related compounds on lipid peroxidation and free radical scavenging activity-some structural aspects. J. Pharm Pharmacol. 1991; 43: 486-491. Yoganarasimhan SN. Medicinal plants of India. Karnataka Vol.I, Bangalore: Cybermedia; 2000. p. 266. Zoe Merculieff, Shubharani Ramnath, Seetha lakshmi Madhukar Sankoli, Sivaram Venkataramegowda, Ganti S. Murthy and Ruben Michael Ceballos: Phytochemical, antioxidant and antibacterial potential of <em>Elaeagnuskologa</em> (Schlecht.) leaf, Asian Pac J Trop Med. 2014; 7(Suppl 1): S599-S602.
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3

Freire, *Rafael, Marcos Fidry, Clara Faria, et al. "SAFETY AND EFFICACY OF MONOAMINE OXIDASE INHIBITORS IN THE TREATMENT OF ANXIETY DISORDERS: A SYSTEMATIC REVIEW AND META-ANALYSIS." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i267—i268. https://doi.org/10.1093/ijnp/pyae059.472.

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Abstract Background Monoamine oxidase inhibitors (MAOI) are well known for its effectiveness on major depressive disorder. MAOI’ s prescription has been declining since the arrival of new antidepressant drugs, and there are few studies on their efficacy and safety in the treatment of anxiety disorders. MAOI are controversial drugs because, in one hand, their efficacy is potentially superior to other antidepressants, due to their distinct mechanism of action. On the other hand, there are concerns about safety of these medications. Aims and Objectives The authors performed a systematic review and meta- analysis to investigate the efficacy and safety of MAOI. We also looked for evidence of superiority over other stablished drugs. Methods MEDLINE, PsycINFO, Web of Science, EMBASE, The Cochrane Library, Cochrane Central Register of Controlled Trials and ClinicalTrials.gov were searched for clinical trials using MAOI on anxiety disorders treatment, from January 1980 to May 2023. Review Manager 5 was used to analyze the effect size data, used as primary outcome. Results Over 2,972 records, 24 studies were included in the review. 19 studies were on social anxiety disorder treatment, 7 on panic disorder treatment. The studied MAOI were moclobemide, phenelzine, brofaromine and tranylcypromine. MAOI were superior to placebo in all 13 randomized controlled trials (RCT), except 2. MAOI were not superior to other antidepressants in comparative trials. They were effective on all 7 comparative trials and 4 open trials. 1,535 patients were pooled, only 6 (0.4%) showed severe adverse effects during trials. The risk of bias was high among the studies. Discussion and Conclusion MAOIs are effective treatments for social anxiety and panic disorders, although literature is scarce and there is high risk of bias. These medications demonstrated to be safe and effective. More clinical trials, with more stringent methodology are needed. References Lam RW, Kennedy SH, Grigoriadis S, McIntyre RS, Milev R, Ramasubbu R, Parikh S V, Patten SB, Ravindran A V. Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. III. Pharmacotherapy. J Affect Disord. Netherlands; 2009 Oct;117 Suppl:S26-43. PMID: 19674794 Katzman MA, Bleau P, Blier P, Chokka P, Kjernisted K, Van Ameringen M, Antony MM, Bouchard S, Brunet A, Flament M, Rabheru K, Grigoriadis S, Richter PMA, Mendlowitz S, O’ Connor K, Robichaud M, Walker JR, Asmundson G, Klassen LJ, Lam RW, McIntyre RS, Szpindel I. Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry. 2014. PMID: 25081580 Salzer HM, Lurie ML. Anxiety and depressive states treated with isonicotinyl hydrazide (isoniazid). Arch Neurol Psychiatry. 1953; Youdim MBH, Edmondson D, Tipton KF. The therapeutic potential of monoamine oxidase inhibitors. Nature Reviews Neuroscience. 2006. PMID: 16552415 Wimbiscus M, Kostenko O, Malone D. MAO inhibitors: Risks, benefits, and lore. Cleve Clin J Med. 2010; PMID: 21147941 ARNOT R. Calming effect of the monoamine oxidase inhibitors. Dis Nerv Syst. United States; 1960 Aug;21:448. PMID: 13794397Zisook S. A clinical overview of monoamine oxidase inhibitors. Psychosomatics. England; 1985 Mar;26(3):240-246,251. PMID: 3887453 Flockhart DA. Dietary restrictions and drug interactions with monoamine oxidase inhibitors: An update. Journal of Clinical Psychiatry. 2012. PMID: 22951238 Balon R, Mufti R, Arfken CL. A survey of prescribing practices for monoamine oxidase inhibitors. Psychiatr Serv. United States; 1999 Jul;50(7):945–947. PMID: 10402617 Fiedorowicz JG, Swartz KL. The role of monoamine oxidase inhibitors in current psychiatric practice. Journal of Psychiatric Practice. 2004.
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4

Domashevskaya, Evelina P., Van Tu Chan, Anatoly N. Lukin, Sergey V. Sitnikov та Oleg V. Stognay. "МЕЖАТОМНЫЕ СВЯЗИ В АМОРФНЫХ КОМПОЗИТАХ (CoFeB)x(TiO2)1–x C РАЗНЫМ СОДЕРЖАНИЕМ МЕТАЛЛИЧЕСКОЙ И ДИЭЛЕКТРИЧЕСКОЙ КОМПОНЕНТ ПО ДАННЫМ ИК-СПЕКТРОСКОПИИ". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, № 3 (2019): 374–84. http://dx.doi.org/10.17308/kcmf.2019.21/1151.

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Методом ионно-лучевого распыления двух мишеней (одна из сплава CoFeB, вторая из TiO2) на вращающуюся ситалловую подложку получена серия образцов с градиентом состава и толщины композита (CoFeB)x(TiO2)1–x. На дифрактограммах aморфных композитов обнаружено гало, соответствующее среднему межатомному расстоянию, близкому по величине к значениям межплоскостных расстояний самых интенсивных дифракционных линий в сплавах CoFe. Методом ИК-спектроскопии проведена идентификация мод, соответствующих межатомным связям в аморфных композитах (CoFeB)x(TiO2)1–x различного состава. Установлено наличие связей с кислородом всех элементов композита Fe–O, Co–O, Ti–O, B-O, а также образование промежуточных химических связей Ti–O–B, Ti–O–Co между атомами диэлектрической и металлической компонент композита. На основе полученных данных предложена модель аморфных композитов (Co45Fe45B10)x(TiO2)1–x, в которой металлические частицы представляются в виде ядра из металлических кластеров CoFe с оболочкой из оксидов и боридов/оксиборидов d-металлов, распределенных в диэлектрической матрице диоксида титана TiO2–х.&#x0D; &#x0D; ИСТОЧНИК ФИНАНСИРОВАНИЯРабота выполнена при поддержке Минобрнауки России в рамках государственного заданияВУЗам в сфере научной деятельности на 2017–2019 годы. Проект № 3.6263.2017/ВУ.&#x0D; &#x0D; &#x0D; &#x0D; REFERENCES &#x0D; &#x0D; Zolotukhin I. V., Kalinin Yu. E., Stognay O. V. New directions of physical materials science. Voronezh, Voronezh State University Publ., 2000, 456 p. (in Russ.)&#x0D; Gridnev S. A., Kalinin Yu. E., Sitnikov A. V., Stognay O.V. Nonlinear phenomena in nano- and microheterogeneous systems. Moscow, BINOM. Lab knowledge Publ., 2012, 352 p. (in Russ.)&#x0D; Stognay O. V. Electric transport and magnetic properties of amorphous nano-granulated metal-dielectric composites. Doc. Sci. diss, Voronezh, 2004, 280 p.&#x0D; Diany B., Serious V.S., Metin, Parkin S., Gurney B. A., Baumgart P., Wilhoit D. R. Magnetotransport properties of magnetically soft spin-valve structures. J. Appl. Phys., 1991, v. 69(9), pp. 4774–4779. https://doi.org/10.1063/1.348252&#x0D; Kalinin Yu. E., Sitnikov A. V., Stognei O. V., Zolotukhin I.V., Neretin P.V. Electrical properties and giant vagnetoresistance of the CoFeB–SiO2 amorphous granular composites. Materials Science and Engineering: A, 2001, v. 304–306, pp. 941–945. https://doi.org/10.1016/s0921-5093(00)01606-3&#x0D; Kotov L. N., Turkov V. K., Vlasov V. S., Lasek M. P., Kalinin Yu. E., Sitnikov A. V. Conductive, magnetic and structural properties of multilayer fi lms. IOP Conf. Series: Materials Science and Engineering, 2013, v. 47. 012027. https://doi.org/10.1088/1757-899X/47/1/012027&#x0D; Domashevskaya E. P., Storozhilov S. A., Turishchev S. Yu., Kashkarov V. M., Terekhov V. A., Stogney O. V., Kalinin Yu. E., Sitnikov A. V., Molodtsov S. L. XANES and USXES studies of interatomic interactions in (Co41Fe39B20)x(SiO2)1−x nanocomposites. Physics of the Solid State, 2008, v. 50(1), pp. 139–145. https://doi.org/10.1134/S1063783408010253&#x0D; Shchekochikhin A. V., Domashevskaya E. P., Karpov S. I. Effect of elemental composition based on CoFeB-SiO2 on magnetic and magnetoresistive properties. Kondensirovannye sredy i mezhfaznye granitsy [Condensed Matter and Interphases], 2006, v. 8(1), pp. 64–66. URL: http://www.kcmf.vsu.ru/resources/t_08_1_2006_013.pdf (in Russ.)&#x0D; Domashevskaya E. P., Chan Van Tu, Chernyshev A. V., Lukin A. N. Investigation of the interato mic interaction in multilayer nanostructures (Co45Fe45Zr10/a-Si)40 and (Co45Fe45Zr10/SiO2) by method of IR-spectroscopy and small angle diffraction. Condensed Matter and Interphases, 2017, v. 19(2), pp. 195–204. https://doi.org/10.17308/kcmf.2017.19/192 (in Russ.)&#x0D; JCPDS − International Centrefor Diffraction Data. 2001, no. 51−0740.&#x0D; JCPDS − International Centre for Diffraction Data. 2001, no. 49−1588.&#x0D; JCPDS − International Centre for Diffraction Data. 2001, no. 48−1817.&#x0D; Kongfa Chen, Lihua Fang, Teng Zhang, San Ping Jiang. New zinc andbismuth doped glass sealants with substantially suppressed borondeposition and poisoning for solid oxide fuel cells. J. Mater. Chem. A, 2014, v. 2(43), pp. 18655–18665. https://doi.org/10.1039/c4ta02951h&#x0D; Wenjie Zhang, Bo Yang, Jinlei Chen. Effects of calcination temperature on preparation of borondoped TiO2 by sol-gel method. International Journal of Photoenergy, 2012, v. 2012, pp. 1–8. https://doi.org/10.1155/2012/528637&#x0D; Rihcard A., Nyquistand R., Kagel O. Infrared Spectra of Inorganic Compounds. New York and London, Academic Press, 1971, 499 p.&#x0D; Milovanov Yu. S., Kuznetsov G. V., Skryshevsky V. A., Stupan S. M. Transport of Charge in Nanocomposite Structures of Silicon-SiO2, Silicon-TiO2. Semiconductors, 2014, v. 48(10), pp. 1335–1341. https://doi.org/10.1134/s1063782614100200&#x0D; Chetverikova A. G., Maryakhina V. S. Studies of polymineral clay containing three-layer aluminosilicates by physical methods. Bulletin of the Orenburg State University, 2015, no. 1 (176), pp. 250–255. (in Russ.)&#x0D; Shchekochikhin A. V., Domashevskaya E. P., Karpov S. I., Stognei O. V. Interatomic interaction and modes of IR spectra in amorphous nanocomposites (Co45Fe45Zr10)x(SiO2)1–x. Proceedings of Voronezh State University. Series: Physics. Mathematics, 2008, no. 1, pp. 109–114. URL: http://www.vestnik.vsu.ru/pdf/physmath/2008/01/schekochihin.pdf (in Russ.)&#x0D; María E., Pérez Bernal, Ricardo J., Ruano Casero, Vicente Rives. Mixed Oxides Co-Fe Mixed Oxides &amp; Calorie/Calcination of Layered Double. Ceramics– Silikáty, 2004, v. 48(4), pp. 145–154. URL: https://www.irsm.cas.cz/materialy/cs_content/2004/Bernal_CS_2004_0000.pdf&#x0D; Nicholas T. Nolan, Michael K. Seery, Suresh C. Pillai. Spectroscopic investigation of the anatase-torutile transformation of sol-gel synthesised TiO2 photocatalysts // J. of Physical Chemistry C, 2009, v. 113, pp. 16151–16157. https://doi.org/10.1021/jp904358g&#x0D; &#x0D;
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5

Yee, Mei Yi, Ewen Harrison, Riinu Pius, and Michael Gillies. "Changes in perioperative red cell transfusion practice over time in patients undergoing surgery for upper gastrointestinal and liver cancer: a retrospective cohort study at a single tertiary centre." BMJ Open 12, no. 5 (2022): e054193. http://dx.doi.org/10.1136/bmjopen-2021-054193.

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ObjectivesOptimum transfusion trigger for adults undergoing cancer surgery is uncertain. Published guidelines recommend restrictive transfusion strategies in hospitalised adults. We aimed to measure the red cell transfusion rate and haemoglobin trigger in patients undergoing cancer surgery and how closely practice reflected published guidelines.DesignRetrospective cohort study.SettingSingle tertiary centre.ParticipantsAdult patients undergoing surgery for upper gastrointestinal or liver malignancy.ExposurePostguideline change (2015–2017) versus preguideline change (2011–2012).Outcome measuresPrimary: transfusion rate, secondary: transfusion trigger. Multivariable logistic regression was used to assess factors and adjust for confounders affecting our outcome measures.Results1578 surgical records were identified for 1520 patients. 946/1530 (62%) patients had preoperative anaemia. The transfusion rate decreased from 23% in 2011–2012 to 14% in 2015–2017. This change remained significant after adjusting for other variables associated with transfusion rates. Mean pretransfusion haemoglobin in those who were transfused was 78±13 g/L in 2011–2012 and 80±15 g/L in 2015–2017. This change in haemoglobin transfusion triggers was not significant.ConclusionTransfusion rate has decreased over the study period in patients undergoing surgery for malignancy and is consistent with a restrictive transfusion strategy.
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6

Talal, Abdel Raheem, M. Abo Ria Nesreen, K. Abd ElGhafar Noha, and Maher Zeinab. "Serum Desnutrin Level and Acne Severity." Biolife 6, no. 1 (2022): 10–14. https://doi.org/10.5281/zenodo.7397399.

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<strong>ABSTRACT</strong> The role of metabolic factors in pathophysiology of acne is highly controversial. A&nbsp;&nbsp; potential role for various factors such as desnutrin has been suggested in the pathogenesis of acne. The aim of this study was to measure the serum levels of desnutrin and insulin and estimate insulin resistance (HOMA-IR), in acne patients in comparison to normal controls, and evaluate the relationship of these levels to severity of acne, in order to investigate the role of these factors in the pathogenesis of acne. The present study included 60 acne patients and 20 healthy controls. Full history and clinical assessment of acne severity were performed for patients. Body mass index was calculated for patients and controls. Serum samples were collected from patients and controls after fasting for 10 hours for estimation of laboratory parameters (fasting blood sugar, insulin, triglycerides, LDL, HDL and total cholesterol). The homeostasis model assessment of insulin resistance (HOMA-IR) was used to calculate insulin resistance. Desnutrin levels were determined by enzyme-linked immunosorbent assay (ELISA). The results of this study revealed no significant difference in desnutrin, fasting blood sugar, insulin and HOMA-IR between acne patients and controls. No statistically significant difference was detected between patients with mild, moderate and severe acne regarding BMI, laboratory parameters. The present study couldn&rsquo;t prove a significant relation between serum desnutrin, insulin and HOMA-IR levels in acne patients. <strong>Keywords: </strong>Acne, Insulin resistance (HOMA-IR), Desnutrin <strong>REFERENCES</strong> Zaenglein A, Pathy A, Schlosser B, Alikhan A, Baldwin H, Berson D, and Keri J (2016): Guidelines of care for the management of acne vulgaris. <em>Journal of American Academy of Dermatology</em>; <em>74</em>(5): 945-973.<strong>&rlm;</strong> Kurokawa I, Danby F, Ju Q, Wang X, Xiang L, Xia L, Chen W, Nagy I, Picardo M, Suh D, Ganceviciene R, Schagen S, Tsatsou F and Zouboulis C (2009): New developments in our understanding of acne pathogenesis and treatment.<em> Experimental Dermatology</em>; 18: 821&ndash;832. Chen W, Obermayer Pietsch B, Hong J, Melnik B, Yamasaki O, Dessinioti C, Ju Q, Liakou A, Al Khuzaei S, Katsambas A, Ring J and Zouboulis C (2011): Acne-associated syndromes: models for better understanding of acne pathogenesis<em>. Journal of the European Academy of Dermatology and Venereology;</em> 25:&nbsp;637&ndash;646. Karadag A, Ertugrul D, Gunes Bilgili S, Takci Z, Tutal E and Yilmaz H (2013): Insulin resistance is increased in alopecia areata patients. <em>Cutaneous and Ocular Toxicology</em>; 32(2): 102&ndash;106. Villena JA, Roy S, Sarkadi-Nagy E, Kim KH and Sul HS (2004): Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. <em>Journal of Biology and Chemistry;</em> 279:47066&ndash;47075. Jenkins CM, Mancuso DJ, Yan W, Sims HF, Gibson B and Gross RW(2004): Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acyl glycerol transacylase activities. <em>Journal of Biology and Chemistry</em>; 279:48968&ndash;48975. Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A and Zechner R (2004): Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.<em> Science</em>; 306:1383&ndash;1386 Demir B, Ucak H, Cicek D, Aydin S, Erden I, and Dertlioglu S (2014). Changes in serum desnutrin levels in patients with acne vulgaris. <em>European Journal of Dermatology</em>; 24(5): 589&ndash;593. Okita K, Iwahashi H, Kozawa J, Okauchi Y, Funahashi T, Imagawa A and Shimomura I (2013): Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy. <em>Endocrine journal</em>; 60(3): 283-290.<strong>&rlm;</strong> Forbes CD and Jackson WF (2003): In: Color Atlas and Text of Clinical Medicine Ch 9, p 320 336 3<sup>rd</sup> edition <em>Elsevier Science London New York Philadelphia</em>. Saleh NF, Ramadan SA, Zeid OMA, Sabra RA and El Aziz SBA (2011): Role of diet in acne: a descriptive study. <em>Journal of the Egyptian Women&rsquo;s Dermatologic Society</em>; <em>8</em>(2): 66-71. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF and Turner RC (1985): Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. <em>Diabetologia;</em> 28(7):412-419. <strong>&rlm;</strong>Smith RN, Mann NJ, Braue A, Makelainen H and Varigos JA (2007): The effect of a high protein, low glycemic-load diet versus a conventional high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial<em>. Journal of American Academy of Dermatology;</em>57: 247-56. Tayel DI, Abdelsalam OM, Elgarem YF and Ali AE (2013): Dietary Intervention to Alleviate Acne Severity. <em>American Journal of Research Communication;</em> 1(5): 65-79. Kaymak Y, Adisen E, Ilter N, Bideci A, Gurler D and Celik B (2007): Dietary glycemic index and glucose, insulin, insulin like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients with acne.<em> Journal of American Academy of Dermatology</em>; 57(5):819-23. Ismail NH, Abdl Manaf Z, and Azizan NZ (2012): High glycemic load diet, milk and ice cream consumption are related to acne vulgaris in Malaysian young adults. <em>BMC Dermatology Journal</em>; 12(13):1-8. Lu PH and Hsu CH (2015): Body mass index is negatively associated with acne lesion counts in Taiwanese women with post‐adolescent acne. <em>Journal of the European Academy of Dermatology and Venereology</em>; <em>29</em>(10): 2046-2050.<strong>&rlm;</strong> Tania Luthra, Rahul Agarwal, Mamidala Estari, Uma Adepally, Subhabrata Sen. A novellibrary of -arylketones as potential inhibitors of &alpha;-glucosidase: Their design, synthesis, invitro and in vivo studies. Nature-Scientific Reports, 2017, 7(1), 1-13. DOI: 10.1038/s41598- 017-13798-y. Tsai M, Chen WC, Cheng Y, Wang CY, Chen GY and Hsu TJ (2006): Higher body mass index is a significant risk factor for acne formation in school children<em>. European Journal of Dermatology; </em>16: 251-3. Di Landro A, Cazzaniga S, Parazzini F, Ingordo V, Cusano F and Atzori L, Cutr&igrave; FT, Musumeci ML, Zinetti C, Pezzarossa E, Bettoli V, Caproni M, Lo Scocco G, Bonci A, Bencini P and Naldi L (2012): Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults. <em>Journal of American Academy Dermatology; </em>67: 1129&ndash;1135. Halvorsen JA, Vleugels RA, Bjertness E and Lien L (2012): A population-based study of acne and body mass index in adolescents.<em> Archieves of Dermatology; </em>148: 131&ndash;132<em>.</em> Abulnaja KO (2009): Changes in the hormone and lipid profile of obese adolescent Saudi females with acne vulgaris.<em> Brazilian Journal of Medical and Biological Research; </em>42(6) 501-505. Balta I, Ekiz O, Ozuguz P, Ustun I, Karaca S, Dogruk KS and Eksioglu M (2015): Insulin resistance in patients with post-adolescent acne<em>. International Journal of</em> <em>Dermatology;</em> 54: 662&ndash;666. &Ccedil;etin&ouml;zman F, Yazgan Aksoy D, El&ccedil;in G and Yıldız BO (2014): Insulin sensitivity, androgens and isotretinoin therapy in women with severe acne. <em>Journal of Dermatological Treatment</em>; <em>25</em>(2): 119-122.<strong>&rlm;</strong> Ertugrul DT, Karadag AS, Tutal E and Akin KO (2011): Isotretinoin does not induce insulin resistance in patients with acne. <em>Clinical and Experimental Dermatology</em>; 36(2): 124-128.<strong>&rlm;</strong> Del Prete M, Mauriello MC, Faggiano A, Di Somma C, Monfrecola G, Fabbrocini G and Colao A (2012): Insulin resistance and acne: a new risk factor for men. <em>Endocrine</em>; <em>42</em>(3): 555-560.<strong>&rlm;</strong> Frohnert BI, Jacobs DR Jr., Steinberger J, Moran A, Steffen LM and Sinaiko AR (2013): Relation between Serum Free Fatty Acids and Adiposity, Insulin Resistance, and Cardiovascular Risk Factors from Adolescence to Adulthood.<em> Diabetes; </em>62(9):3163-3169.&nbsp; Arora MK, Seth S and Dayal S (2010): The relationship of lipid profile and menstrual cycle with acne vulgaris<em>. Clinical Biochemestry; </em>43: 1415- 1420 El-Akawi Z, Abdel-Latif N, Abdul- Razzak K and Al-Aboosid M (2007): The Relationship between Blood Lipids Profile and Acne. <em>Journal of Health Science, </em>53(5): 596&ndash;599
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7

Freedman, Saul D. "The intersection graph of a finite simple group has diameter at most 5." Archiv der Mathematik 117, no. 1 (2021): 1–7. http://dx.doi.org/10.1007/s00013-021-01583-3.

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AbstractLet G be a non-abelian finite simple group. In addition, let $$\Delta _G$$ Δ G be the intersection graph of G, whose vertices are the proper non-trivial subgroups of G, with distinct subgroups joined by an edge if and only if they intersect non-trivially. We prove that the diameter of $$\Delta _G$$ Δ G has a tight upper bound of 5, thereby resolving a question posed by Shen (Czechoslov Math J 60(4):945–950, 2010). Furthermore, a diameter of 5 is achieved only by the baby monster group and certain unitary groups of odd prime dimension.
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Bahari, Gholamreza, Mohammad Hashemi, Mohsen Taheri, Mohammad Naderi, Ebrahim Eskandari-Nasab, and Mahdi Atabaki. "Association of IRGM Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeast Iran." Scientific World Journal 2012 (2012): 1–5. http://dx.doi.org/10.1100/2012/950801.

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Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. IRGM1 is an important protein in the innate immune response against intracellular pathogens by regulating autophagy. Polymorphisms in the IRGM genes are known to influence expression levels and may be associated with outcome of infections. This case-control study was done on 150 patients with PTB and 150 healthy subjects to determine whether the IRGM polymorphisms at positions −1208 A/G (rs4958842), −1161 C/T (rs4958843), and −947 C/T (rs4958846) were associated with PTB. The polymorphisms were determined using tetra-amplification refractory mutation system-PCR (T-ARMS-PCR). The results showed that the IRGM −1161 C/T and −947 C/T polymorphisms were associated with decreased susceptibility to PTB (OR = 0.06, 95% CI = 0.03–0.13,P &lt; 0.001 and OR = 0.27; 95% CI = 0.013–0.55,P &lt; 0.001, resp.). No significant difference was found among the groups regarding −1208 A/G polymorphism. In conclusion we found that the IRGM −1161 C/T and −947 C/T polymorphisms but not −1208 A/G polymorphism provide relative protection against PTB in a sample of Iranian population.
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Nadtochy, V. A., and N. V. Kolpakov. "Macrozoobenthos of the Olyutorsky Bay (Bering Sea) a quarter of century later: composition, distribution, communities." Izvestiya TINRO 202, no. 1 (2022): 161–71. http://dx.doi.org/10.26428/1606-9919-2022-202-161-171.

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Results of two bottom grab surveys in the Olyutorsky Bay of the Bering Sea conducted in 1985 (37 stations with 60 samples in the depth range of 20–200 m) and 2012 (26 stations with 48 samples at the depths of 51–270 m) are compared. Average biomass of macrozoobenthos was rather stable: 561.1 ± 95.2 g/m2 in 1985 and 581.3 ± 94.5 g/m2 in 2012. Sea urchins, bivalves and polychaetes dominated by biomass in 1985 (84.7 % of the total biomass for these 3 groups), but sipunculids appeared in the list of the dominant taxonomic groups in 2012 when 91.3 % of the total biomass consisted of the top 4 groups. The main communities of macrozoobenthos practically retained their location and quantitative parameters. There is concluded that composition, distribution and abundance of macrozoobenthos in the Olyutorsky Bay were stable over a quarter of century.
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Zavala, Sofia, Samantha Rosas, Arlene Calvo, Nestor Sosa, German Henostroza, and Ana Belen Arauz Rodriguez. "783. Characterization of Non-tuberculous Mycobacteria Isolates in a National Mycobacterial Laboratory in Panama: 2012–2015." Open Forum Infectious Diseases 5, suppl_1 (2018): S280. http://dx.doi.org/10.1093/ofid/ofy210.790.

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Abstract Background Nontuberculous mycobacteria (NTM) are becoming more frequently isolated in microbiology laboratories. There is no standardized diagnosis, treatment, and/or monitoring of patients with NTM disease. We described the experience of the Panama National Mycobacterial Laboratory in isolating NTM in patients suspected to have active tuberculosis in Panama. Methods Data registries of the National TB Program Laboratory of Panama between 2012 and 2015 were reviewed. Demographic information, relevant history, sample source, and isolate identified for each specimen obtained at the time of specimen submission was extracted. Identification of mycobacterial species were made using culture and PCR. Data were exported to an Excel workbook and a descriptive analysis was performed using STATA. Results A total of 4,545 samples were received during this period. Of these, 288 (6.3%) were not processed. From the remaining 4,257 samples, 705 (16.5%) were negative, 2,783 (65.3%) were positive for M. tuberculosis, and 769 (18%) were confirmed NTM. NTM species identification was achieved in 715 (93%) using PCR. Median age was 55 years (0 – 92); 49.4% were male. The most frequent NTM isolate was M. avium complex in 172 (22.3%) samples, followed by M. fortuitum in 131 (17%). M. chelonae was isolated in 98 (12.7%) samples, M. gordonae in 50 (6.5%), M. scrofulaceum in 20 (2.6%), and M. triviale in 16 (2.0%). NTM isolation steadily rose over the study period with 490 (63.7%) of the samples being from 2015 and 465 (94.5%) of these typified by PCR. Specimens mainly originated from the Panama metropolitan area (88.2%) and were mostly sputum samples (70.8%). Conclusion Nontuberculous mycobacteria represented an important proportion of isolates among TB suspects in Panama. The implementation of more sensitive diagnostic techniques is increasing the recovery of NTM. Further evaluation of the clinical significance of these finding is required for appropriate guideline implementation. Disclosures G. Henostroza, Aeras: Investigator, Grant recipient.
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Almeida, Maria Tereza Carvalho, Fernanda Alves Maia, Maria das Mercês Borém Correa Machado, et al. "Desenvolvimento docente: avaliação de uma experiência em um curso de Medicina (Teacher development: evaluation of an experience in a Medical course)." Revista Eletrônica de Educação 13, no. 1 (2019): 306. http://dx.doi.org/10.14244/198271992635.

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The objective of this study was to evaluate the actions offered in the Teacher Development Program from the perceptions of the teachers of the medical course of a public university that has been working with active teaching and learning methods since 2002. After each action of the program, an evaluation instrument was applied to the participants, and the answers were submitted to content analysis and then organized into three categories: infrastructure and logistics, the teaching-learning strategies and the developed content. Teachers highlight the importance of organization and planning of activities and the environment in which these actions are developed; they emphasize the importance of using teaching–learning strategies that allow greater re?ection on own practice and the integration of theory and practice. They point out that the themes proposed were timely and necessary, they recognize the importance of being in development, they talk about the motivation from the experiences lived. It is concluded that the Teacher Development is a process through which the teacher is in transformation, through a conscious and constant reflection of his own practice. This process can be promoted by institutional investments and by the regulatory mechanisms of institutions, constituted of an evaluation referenced in objective indicators, consistent with the goals to be achieved. In this sense, it is necessary to invest in permanent education, because long-term programs allow the development of the teacher´s and the institution´s needs.ResumoO objetivo deste estudo foi avaliar as ações oferecidas em um Programa de Desenvolvimento Docente a partir da percepção dos professores do curso de medicina de uma universidade pública que utiliza métodos ativos de ensino-aprendizagem desde 2002. Após cada ação do programa, um instrumento de avaliação foi aplicado aos participantes, e respostas foram submetidas à análise do conteúdo e em seguida foram organizadas em três categorias: infraestrutura e logística, estratégias de ensino-aprendizagem utilizadas, e conteúdo desenvolvido. Os professores destacam a importância da organização e planejamento das atividades e do ambiente em que essas ações se desenvolveram; Enfatizam a importância de utilizar estratégias de ensino-aprendizagem que possibilitem maior reflexão sobre a própria prática e a integração da teoria e a prática. Apontam que os temas propostos foram oportunos e necessários, reconhecem a importância de estarem em desenvolvimento, falam sobre a motivação a partir das experiências vivenciadas. Conclui-se que o Desenvolvimento Docente é um processo pelo qual o professor está em transformação, por meio de uma re?exão consciente e constante de sua própria prática. Esse processo pode ser promovido pelos investimentos institucionais e pelos mecanismos reguladores das instituições constituídos por uma avaliação referenciada em indicadores objetivos, coerentes com as metas a serem alcançadas. Nesse sentido, é necessário investir na educação permanente, pois os programas em longo prazo permitem trabalhar as necessidades do professor e da instituição.ResumenEl objetivo de este estudio fue evaluar las acciones ofrecidas en un Programa de Desarrollo Docente a partir de la percepción de los profesores del curso de medicina de una universidad pública que utiliza métodos activos de enseñanza - aprendizaje desde 2002. Después de cada acción del programa, un instrumento de evaluación se aplicó a los participantes, y las respuestas se sometieron al análisis del contenido y luego se organizaron en tres categorías: infraestructura y logística, estrategias de enseñanza - aprendizaje utilizadas, y contenido desarrollado. Los profesores destacan la importancia de la organización y planificación de las actividades y del ambiente en que esas acciones se desarrollaron; Enfatizan la importancia de utilizar estrategias de enseñanza - aprendizaje que posibiliten una mayor reflexión sobre la propia práctica y la integración de la teoría y la práctica. Se señalan que los temas propuestos fueron oportunos y necesarios, reconocen la importancia de estar en desarrollo, hablan sobre la motivación a partir de las experiencias vivenciadas. Se concluye que el Desarrollo Docente es un proceso por el cual el profesor está en transformación, por medio de una re?exión consciente y constante de su propia práctica. Este proceso puede ser promovido por las inversiones institucionales y por los mecanismos reguladores de las instituciones constituidos por una evaluación referenciada en indicadores objetivos, coherentes con las metas a ser alcanzadas. En este sentido, es necesario invertir en la educación permanente, pues los programas a largo plazo permiten trabajar las necesidades del profesor y de la institución.Keywords: Educational development, Medical education, Professional development, Qualitative research.Palavras-chave: Desenvolvimento e educação, Formação médica, Desenvolvimento profissional, Pesquisa qualitativa.Palabras claves: Desarrollo y educación, Formación médica, Desarrollo profesional, Investigación cualitativa.ReferencesABID, Kauser. Faculty development: a need in time for educators in healthcare. J Pak Med Assoc, v. 63, n. 4, p. 428-431, Apr., 2013.ALMEIDA, Maria Tereza Carvalho; BATISTA, Nildo Alves. Ser docente em métodos ativos de ensino-aprendizagem na formação do médico. Rev Bras Educ Med, v. 35, n. 4, p. 468-476, julho, 2011.ALMEIDA, Maria Tereza Carvalho; MAIA, Fernanda Alves; BATISTA, Nildo Alves. Gestão nas escolas médicas e sustentabilidade dos programas de desenvolvimento docente. Avaliação: Revista da Avaliação da Educação Superior, v. 18, n. 2, p. 299-310, jul., 2013.ANDERSON, Winston A. et al. Changing the culture of Science Education at research universities. Science Education, v. 331, p.152-153, Jan., 2011.ARMSTRONG, Elizabeth G.; BARSION, Sylvia J. Creating “Innovator’s DNA” in Health Care Education. Academic Medicine, v. 88, n. 3, p. 342-348, Mar., 2013.ARMSTRONG, Elizabeth G.; DOYLE, Jennifer; BENNETT, Nancy L. Transformative professional development of physicians as educators: assessment of a model. Academic Medicine, v. 78, n. 7, p. 702-708, Jul., 2003.AUSUBEL, David Paul. A aprendizagem significativa: a teoria de David Ausubel. São Paulo: Moraes, 1982.BALMER, Dorene F.; RICHARDS, Boyd F. Faculty development as transformation: Lessons learned from a process-oriented program. Teaching and learning in medicine, v. 24, n. 3, p. 242-247, Jul., 2012.BARDIN, Laurence. Análise de conteúdo. 3ed. Lisboa: Almedina, 2004.CATE, Olle Ten et al. Faculty development through international exchange: The IMEX initiative. Medical teacher, v. 36, n. 7, p. 591-595, Jun., 2014.CECIM, Ricardo Burg. Educação permanente em saúde: desafio ambicioso e necessário. Interface – Comunicação, Saúde e Educação, v. 9, n. 16, p. 161-177, fev., 2005.CENTRA, John A. Types of faculty development programs. The Journal of Higher Education, v. 49, n. 2, p. 151-162, 1978.CHOU, Calvin L. et al. The Impact of a Faculty Learning Community on Professional and Personal Development: The Facilitator Training Program of the American Academy on Communication in Healthcare. Academic Medicine, v. 89, n. 7, p. 1051-1056, Jul., 2014.COSTA, Nilce Maria da Silva Campos. Docência no ensino médico: por que é tão difícil mudar?. Rev bras educ méd, v. 31, n. 1, p. 21-30, 2007.DEWEY, John. Experiência e Natureza - Lógica - a Arte Como Experiência - Vida e Educação - Teoria da Vida moral. 2 ed. São Paulo: Abril cultural, 1985.DONABEDIAN, Avedis. Evaluating physician competence. Bulletin of the World Health Organization, v. 78, n. 6, p. 857-860, 2000.EBRAHIMI, Sedigheh; KOJURI, Javad. Assessing the Impact of Faculty Development Fellowship in Shiraz University of Medical Sciences. Arch Iran Med, v. 15, n. 2, p. 79-81, Feb., 2012.FREIRE, Paulo. Pedagogia da autonomia: saberes necessários à prática educativa. São Paulo: Paz e Terra, 1996.GADAMER, Hans Georg. Verdade e Método: traços fundamentais de uma hermenêutica filosófica. Petrópolis: Vozes, 1999.HABERMAS, Jurgen. Conhecimento e interesse. Rio de Janeiro: Ed. Zahar, 1987.KIRKPATRICK, Donald L. Como implementar os quatro níveis de avaliação de treinamento de equipes: um guia prático. 1 ed, Rio de Janeiro: Artmed, 2010.KNIGHT, Amy M. et al. Long?Term Follow?Up of a Longitudinal Faculty Development Program in Teaching Skills. Journal of general internal medicine, v. 20, n. 8, p. 721-725, Aug., 2005.MOORE, Philippa. Logros más alla de los objetivos: evaluación cualitativa de un programa de formación en educación médica. Revista médica de Chile, v. 142, n. 3, p. 336-343, mar., 2014.MORAHAN, Page S.; FLEETWOOD, J. Do we really value what our faculty do? Academic Physician &amp; Scientist, p. 7-9, Sep.-Oct., 2009.NÓVOA, António. Formação de professores e profissão docente. Lisboa: Publicações Dom Quixote. Cap. 1, p. 1-27. 1992.PELIZZARI, Adriana et al. Teoria da aprendizagem significativa segundo Ausubel. Revista PEC, v. 2, n. 1, p. 37-42, jul., 2002.PERRON, Noelle Junod et al. Impact of a faculty development program for teaching communication skills on participants’ practice. Postgraduate medical journal, v. 90, n. 1063, p. 245-250, Apr., 2014.SARIKAYA, Ozlem et al. The impact of a faculty development program: evaluation based on the self-assessment of medical educators from preclinical and clinical disciplines. Advances in physiology education, v. 34, n. 2, p. 35-40, Jun., 2010.SCHÖN, Donald. A. Formar professores como profissionais reflexivos. In: NÓVOA, Antônio. Os professores e sua formação. Lisboa: Dom Quixote. v. 2, p. 77-91, 1992.SIMPSON, Deborah et al. Fifteen years of aligning faculty development with primary care clinician–educator roles and academic advancement at the Medical College of Wisconsin. Academic Medicine, v. 81, n. 11, p. 945-953, Nov., 2006.SINGH, Tejinder et al. Impact of a fellowship program for faculty development on the self-efficacy beliefs of health professions teachers: A longitudinal study. Medical teacher, v. 35, n. 5, p. 359-364, Jun., 2013.STEINERT, Yvonne et al. A systematic review of faculty development initiatives designed to improve teaching effectiveness in medical education: BEME Guide No. 8. Medical teacher, v. 28, n. 6, p. 497-526, Sep., 2006.STEINERT, Yvonne et al. Faculty development as an instrument of change: A case study on teaching professionalism. Academic Medicine, v. 82, n. 11, p. 1057-1064, Nov., 2007.WILKERSON, LuAnn; IRBY, David M. Strategies for improving teaching practices: a comprehensive approach to faculty development. Academic Medicine, v. 73, n. 4, p. 387-396, Apr., 1998.
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Kucharski, Mirosław, Urszula Kaczor та Katarzyna Piórkowska. "Genetic Variability in the Loci of FABP4, PPARγ and SCD Genes of Sheep Breeds Raised for Different Purposes". Annals of Animal Science 19, № 4 (2019): 937–54. http://dx.doi.org/10.2478/aoas-2019-0033.

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AbstractThe present study was undertaken to analyse the genetic variation in coding sequences, splicing sites and regulatory sequences of FABP4, PPARγ and SCD genes in five breeds of sheep raised in Poland with different purposes: meat (Suffolk, Ile de France), dairy/prolific (Olkuska sheep, Kołuda) and primitive breeds (Polish Mountain Sheep). To identify genetic variability HRM-PCR, sequencing and PCR-RFLP method were used. Determining the genetic structure of the mentioned genes revealed six SNPs: FABP4 – c.73 + 13A&gt;T and c.348 + 85G&gt;A, PPARγ – c.391 – 66C&gt;T (c.481 – 66C&gt;T) and c.529 + 27G&gt;C (c.619 + 27G&gt;C), SCD – c.*945G&gt;A and c.*1116A&gt;G. For the c.*1116A&gt;G SNP, a potential association with specific sheep body type and breeding purpose was found. In turn, the substitution c.*945G&gt;A located in the regulatory region of the 3'-UTR of the Ovis aries SCD gene was identified for the first time. Based on the relationship demonstrated between sheep body constitution and productive type (dairy, meat) and the polymorphism of the SCD gene, further research is needed. The correlation between c.*1116A&gt;G polymorphism and growth rate, slaughter and carcass value as well as meat quality of lambs needs to be studied in more detail. Such studies may lead to more effective selection processes in sheep breeding in the future.
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Ogane, Shinya, Riku Sato, Yuta Tanaka, Kazumasa Tsutsui, and Koji Moriguchi. "(Digital Presentation) Development of an Eam-Type Interatomic Potential Model Reproducing Theoretical Energetics in Polytype Structures." ECS Meeting Abstracts MA2022-01, no. 55 (2022): 2286. http://dx.doi.org/10.1149/ma2022-01552286mtgabs.

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The allotropes composed of close-packed (CP) structures that differ only in the stacking order in the system are called the CP polytypes [1]. The CP polytype is also considered one of the physical systems realizing the Kepler conjecture [2]. Since the significant changes in physical properties due to the intentional polytype formation have been reported in various fields of metallic and semiconductive systems [3-5], the material engineering demand for polytype phase control is diverse. The acquisition and deepening of scientific knowledge for the polytype phase control is therefore promising to lead to the creation of new functional materials. However, the scientific control of the polytype stacking order is still incomplete in the field of practical materials engineering. This is because the polytype control technology has many uncertainties since the formation mechanism of polytype is physically unsolved yet. Predicting polytype phase stability for a material has also been a long-standing issue in condensed matter physics and/or materials science. This situation stems from the fact that the atomistic interactions on polytype energetics might be surprisingly quite complex and delicate despite the simplicity of their geometrical structure. In the previous paper, we have presented an analytical theory on the total energetics for the CP polytypes based on the geometrical analysis for the correlation between interlayer interactions and interatomic ones in CP polytypes [6]. Our theoretical studies have shown that the long-range nature of interatomic interactions is an important factor for reproducing the static polytype energetics [6,7]. Based on our theory submitted [6], we have tried to construct an EAM (Embedded Atom Method) [8] type interatomic model for metallic La reproducing the theoretical polytype energetics. Our primary motivation for the present study is to grasp why long periodic polytype structures other than 2H and 3C ones appear as the stable phase under the crystal growth for the specific elemental systems. Therefore, we aim to develop the interatomic potential to reproduce the theoretical polytype energetics and to adopt it to the dynamical simulations for the long-periodic polytypes systems. The ground state for La is the 4H structure which is the simplest long-periodic polytype and La can exist in both 4H phase and the 3C phase under 583K [9]. Thus, it is possible to investigate the essential factors determining the polytype selection rule through the atomistic dynamics for metallic La. From our research so far, we have succeeded in constructing an EAM-type potential that mimics the energetics of metallic La with the 4H as the ground structure [10]. The following three procedures are found to be essentially important for deriving an interatomic interaction model with the 4H structure as the ground state; (i) The cutoff radius should be set to have a relatively longer distance (three or more interlayer distances in the 4H stacking structure). (ii) The equations of state (EOS) for the energetics of 2H, 3C, and 4H structures need to be reproduced as accurately as possible. (iii) The adiabatic potential along important transition paths between crystal structures such as the Bain path for the bcc-fcc transition must be exactly considered [11]. These procedures have made the interaction model describable for not only the energetics but also the lattice dynamics such as dynamical instability, which is known to be generally significant for the phase transition phenomena [11, 12]. The transferability of the associated potential and some results adapted in the molecular dynamics (MD) simulations will be also discussed in the presentation of the day. [1] A. L.Ortiz et al., J. Appl. Cryst. 46, 242 (2013). [2] T. Hales et al., Forum of Mathematics, Pi, 5, E2 (2017). [3] R. Yakimova et al., J. Cryst. Grow. 217, 255 (2000). [4] Z. Fan et al., Nat. Commun. 6, 7684 (2015). [5] E. M. T. Fadaly et al., Nature. 580, 205 (2020). [6] S. Ogane and K. Moriguchi, MRS Advances 6, 170 (2021). [7] K. Moriguchi et al., MRS Advances 6, 163 (2021). [8] Murray S. Daw and M. I. Baskes, Phys. Rev. B 29, 6443 (1984). [9] B. Love, “Metal Handbook”, Vol. 1, American Society for Metals, Novelty, Ohio, 1961, pp 1230-1231. [10] S. Ogane, et al., 2021 MRS Fall Meeting &amp; Exhibit, CH02.13.05 (2021). [11] K Moriguchi and M Igarashi, Phys. Rev. B 74, 024111 (2006). [12] G. Grimvall et al., Rev. Mod. Phys. 84, 945 (2012). [13] S. Baci et al., Phys. Rev. B 81 (2010) 144507. Figure 1
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Marslin, Gregory, Karthik Siram, Rajendran Selvakesavan, Dariusz Kruszka, Piotr Kachlicki, and Gregory Franklin. "Correction: Marslin, G., et al. Secondary Metabolites in the Green Synthesis of Metallic Nanoparticles. Materials 2018, 11, 940." Materials 12, no. 5 (2019): 806. http://dx.doi.org/10.3390/ma12050806.

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Montanaro, Marco, Roberto Latagliata, Michele Cedrone, et al. "The Platelet COUNT at Diagnosis of Essential Thrombocythemia Is a Prognostic Factor for Thrombosis-Free Survival: Retrospective Analysis on 1201 Patients." Blood 126, no. 23 (2015): 2815. http://dx.doi.org/10.1182/blood.v126.23.2815.2815.

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Abstract The protective effect of higher platelet count at diagnosis of Essential Thrombocythemia (ET) was reported in some papers (Carobbio A. 2011, Palandri F. 2012, Montanaro M., 2014). As at our knowledge, there is no study specifically addressing this point; in this retrospective analysis we have examined 1201 ET patients (pts) followed in 11 Hematological centers of our region from 1/1978 to 12/2010. The diagnosis of ET was made with PVSG, WHO 2001 and WHO 2008 criteria, respectively, according to the period of 1st observation. The main features of our cohort were as follows: median age 62,9 yrs (19-96), male/female 435/766 (36.2%/63.8%), median WBC count 8,8 x 106/L (1.2-57.7), median Hb level 14.0 g/dl (6.0-20.5), median platelet count 813 x 106/L (457-3582), JAK-2V617F mutation in 498/834 performed pts (59,7 %) with a median allele burden of 19.6% (0.2-99.9%), spleen enlargement in 226 pts (18.7%), previous thrombosis in 17.9% of pts (arterial 14.1%, venous 3.8%). The median follow-up of the entire cohort was 7.75 yrs. Thrombosis-free survival curves were plotted according to Kaplan-Meier method and independent risk factors were identified with the Cox proportional-hazards method. At the multivariate analysis, negative prognostic factors for TFS resulted: previous thrombotic events (p= 0.012), age ≥60 yrs (p= 0.008) and spleen enlargement (p= 0.039): on the contrary, platelet count ≥ 944.109/L resulted a protective factor for TFS [p= 0.031 with an HR 0,57 (C.I. 95% 0,35-0,95)]. Receiver operating characteristic (ROC) analyses based on thrombotic events during follow-up were used to identify the baseline platelet count of 944 x 109/L as the best threshold for predicting thrombotic events. Thrombotic events according to this cutoff were 40/384 (10.3%) in pts with platelet count ≥ 944 x 109/L and 109/817 (13.3%) in pts with platelet count &lt; 944 x 109/L. The sites of thrombosis are reported in the table. A comparison of the main features in these two populations showed that pts with PLT count &lt; 944 x 109/L were older (median age 60.4 yrs vs 57.1 yrs, p= 0.016), had a lower median WBC count (8.8 x 109/L vs 10.6 x 109/L, p&lt; 0.0001), an higher median Hb level (14.1 g/dL vs 13.6 g/dL, p&lt; 0.0001) and an higher rate of JAK-2V617F mutation (67.2% vs 41.6%, p&lt; 0.0001); no differences were observed between the two groups as to thrombotic events before diagnosis, spleen enlargement and cardiovascular risk factor (p=NS). As to the treatment, both groups resulted equally treated with anti-aggregant agents (84,6% vs 87,4%, p= 0,76) while in pts with platelet count &lt;944 x 109/L the oral anticoagulants (7.1% vs. 3.1%, p= 0.01) were more often used. Pts with higher platelet count were more frequently treated with cyto-reductive drugs (90,4 % vs 76,4 %, p&lt; 0.0001). No significant difference resulted for Hydroxyurea (70,8 % vs 64,3%, p= 0,34) and Interferon ( 11,7% vs 6,9%, p= 0,07); on the contrary, more pts with higher platelet count were treated with anagrelide (10.7% vs 5.0%, p= 0.001) and alkylating agents (8.9% vs 5.1%, p= 0.03). In conclusion, our retrospective analysis confirmed the protective role for thrombosis of an higher platelet count at diagnosis. Pts with platelet count ≥ 944 x 109/L were more frequently treated with cyto-reductive drugs and this could possibly explain the better TFS, even if the platelet count closer to the occurrence of a thrombotic event resulted near the normal values in both groups. On the other hand, the higher rate of JAK-2V617F mutation in the group of pts with a baseline lower platelet count could be responsible of this counterintuitive finding: it is worth of note, however, that in our series the JAK-2V617F mutation did not result a significant factor for TFS. Table 1.TYPESITEPLTs ≥ 944PLTs &lt;944ARTERIALCardiac10 (2.6%)20 (2.5%)CNS*9 (2.3%)39 (4.8%)Peripheral2 (0.5%)6 (0.7%)Splanchnic1 (0.3%)1 (0.1%)Total22/384 (5.7%)66/817 (8.1%)VENOUSPeripheral17 (4.4%)32 (3.9%)Atypical03 (0.4%)Splanchnic1 (0.2%)7 (0.9%)Total18/384(4.6%)42/817(5.2%)*Central Nervous System; ° Non tested Disclosures No relevant conflicts of interest to declare.
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Li, Xiaoyan, Xinke Zhang, Junji Lin, Kelly Fust, and Jacob Garcia. "Cost Differences of Same-Day Vs Next-Day Use of Pegfilgrastim." Blood 126, no. 23 (2015): 5566. http://dx.doi.org/10.1182/blood.v126.23.5566.5566.

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Abstract Introduction:Febrile neutropenia (FN) is a serious side effect of myelosuppressive chemotherapy that often requires immediate hospitalization. FN is associated with lengthy hospital stays, increased mortality, and high costs. Prophylaxis with granulocyte colony-stimulating factors (G-CSFs) such as pegfilgrastim can reduce risk of FN. Per indication, pegfilgrastim should not be administered between 14 days before and 24 hours after cytotoxic chemotherapy. In most clinical trials, G-CSF has been administered the day following chemotherapy, and administration 1-3 days after chemotherapy may result in a lower risk of infection than same-day administration (Burris et al, J Oncol Pract, 2010; Cheng et al, Anticancer Drugs, 2014; Weycker et al, J Clin Oncol, 2015 [abst e17697]). Thus, both NCCN and ASCO recommend pegfilgrastim be given 1-3 days after chemotherapy when possible. A recent retrospective analysis of US health care claims databases showed that same-day pegfilgrastim was used in 13% of cycles (Weycker et al, Blood, 2014). Here we compare the costs of same- vs next-day use of pegfilgrastim (Neulasta®) from a US payer perspective. Methods: We used a published health economic model on the budget impact of G-CSFs to US payers (Taylor et al, Am J Pharm Benefits, 2012) to estimate differences in per-patient costs associated with same- vs next-day pegfilgrastim use among adult patients with early-stage breast cancer (ESBC) or NHL treated with 1 course (6 cycles) of myelosuppressive chemotherapy (TAC for ESBC; R-CHOP for NHL). Data from 2 phase 2 trials (Burris 2010) and 2 large retrospective studies (Weycker 2015; Cheng 2014) identified in a literature search for studies of FN risk with same- vs next-day use of pegfilgrastim in patients with ESBC or NHL were used to derive plausible ranges of estimated cost differences. Ranges were based on variability in the difference of FN risk between groups as reported in or estimated from these studies. The model assumed patients received prophylactic pegfilgrastim and 1 complete blood cell (CBC) count in each chemotherapy cycle. Percentage of FN events requiring hospitalization and costs associated with pegfilgrastim acquisition, administration, lab work, and FN treatment were derived from published literature and public data sources consistent with Taylor 2012. Chemotherapy costs were assumed to be independent of same- vs next-day pegfilgrastim use and were excluded. All costs are presented in 2015 US dollars. Results: Costs for ESBC were $944 to $6,920 greater per patient per course of chemotherapy with same- vs next-day use of pegfilgrastim. Costs for NHL were $629 to $3,775 greater per patient per course of chemotherapy with same- vs next-day use of pegfilgrastim. See table. Conclusions: This analysis suggests that adherence to next-day use of pegfilgrastim is associated with lower costs than same-day use. Cost differences appear to be driven by FN risk and FN treatment, indicating that these results can be reasonably extrapolated to other regimens with an intermediate/high risk of FN. Table. Estimates of FN Risk and Per-Patient Costs Breast Cancer NHL Burris 2010 Weycker 2015 Burris 2010 Weycker 2015 Cheng 2014 Same Day Next Day Same Day Next Day Same Day Next Day Same Day Next Day Same Day Next Day FN risk (%) 33a 11a 10b 7c 17a 15a 19b 14c 26d 14d Pegfilgrastim acquisition $19,815 $19,815 $19,815 $19,815 $19,815 $19,815 $19,815 $19,815 $19,815 $19,815 Administration $333 $333 $333 $333 $333 $333 $333 $333 $333 $333 CBCs $423 $423 $423 $423 $423 $423 $423 $423 $423 $423 FN treatmente $10,380 $3,460 $3,145 $2,202 $5,347 $4,718 $5,976 $4,404 $8,178 $4,404 Total cost $30,951 $24,031 $23,716 $22,773 $25,918 $25,289 $26,547 $24,974 $28,749 $24,974 Cost differences (next- vs same-day use) (6,920) (944) (629) (1,573) (3,775) Values in parentheses indicate cost savings. a Estimates from Burris 2010; b Estimates from Taylor 2012 for next-day use (7% for TAC and 14% for R-CHOP) were multiplied by relative risk (TAC: 1.36; R-CHOP: 1.33), which was calculated from the cycle-level odds ratio (1.4) reported in Weycker 2015; c Estimates from Taylor 2012; d Estimates from Taylor 2012 for next-day use (14% for R-CHOP) were multiplied by relative risk (1.84), which was calculated from cycle-level results in Cheng 2014 (9.4% for same-day use and 5.1% for next-day use); e Based on current literature, we assumed that the likelihood that an FN event would require hospitalization was 80%. Disclosures Li: Amgen, Inc.: Employment, Equity Ownership. Off Label Use: This abstract describes costs associated with same-day administration of pegfilgrastim, which is an off label use of pegfilgrastim. As noted in the abstract text, "Per indication, pegfilgrastim should not be administered between 14 days before and 24 hours after cytotoxic chemotherapy.". Zhang:Amgen Inc.: Other: Internship. Lin:Amgen Inc.: Employment, Other: stock ownership. Fust:Optum: Employment; Amgen Inc.: Consultancy, Research Funding. Garcia:Amgen Inc: Employment, Equity Ownership.
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Kishore, Amit, Manishi Mukesh, Ranbir C. Sobti, Bishnu P. Mishra, and Monika Sodhi. "Variations in the Regulatory Region of Alpha S1-Casein Milk Protein Gene among Tropically Adapted Indian Native (Bos Indicus) Cattle." ISRN Biotechnology 2013 (January 14, 2013): 1–10. http://dx.doi.org/10.5402/2013/926025.

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Regulatory region of milk protein alpha S1-casein (αS1-CN) gene was sequenced, characterized, and analyzed to detect variations among 13 Indian cattle (Bos indicus) breeds. Comparative analysis of 1,587 bp region comprising promoter (1,418 bp), exon-I (53 bp), and partial intron-I (116 bp) revealed 35 nucleotide substitutions (32 within promoter region, 1 in exon-I, and 2 in partial intron-I region) and 4 Indels. Within promoter, 15 variations at positions −1399 (A &gt; G), −1288 (G &gt; A), −1259 (T &gt; C), −1158 (T &gt; C), −1016 (A &gt; T), −941 (T &gt; G), −778 (C &gt; T), −610 (G &gt; A), −536 (A &gt; G), −521 (A &gt; G), −330 (A &gt; C), −214 (A &gt; G), −205 (A &gt; T), −206 (C &gt; A), and −175 (A &gt; G) were located within the potential transcription factor binding sites (TFBSs), namely, NF-κE1/c-Myc, GATA-1, GATA-1/NF-E, Oct-1/POU3F2, MEF-2/YY1, GATA-1, AP-1, POU1F1a/GR, TMF, GAL4, YY1/Oct-1, HNF-1, GRalpha/AR, GRalpha/AR, and AP-1, respectively. Seventy-four percent (26/35) of the observed SNPs were novel to Indian cattle and 11 of these novel SNPs were located within one or more TFBSs. Collectively, these might influence the binding affinity towards their respective nuclear TFs thus modulating the level of transcripts in milk and affecting overall protein composition. The study provides information on several distinct variations across indicine and taurine αS1-CN regulatory domains.
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Rojas Sánchez, Ahuitz. "SITUACION DE ABUSO SEXUAL BASADO EN IMAGENES EN MEXICO ENTRE 2017 Y 2018 (IMAGED-BASED SEXUAL ABUSE IN MEXICO BETWEEN 2017 AND 2018)." Universos Jurídicos, no. 18 (June 8, 2022): 1–22. http://dx.doi.org/10.25009/uj.vi18.2621.

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Resumen: El objetivo de la presente investigación es explorar la estructura y el contenido de una red de usuarios de abuso sexual basado en imágenes en Twitter. Para ello se analizaron los perfiles de Twitter que contienen la palabra "Quemón o “Nudes” utilizando análisis de redes, técnicas de procesamiento natural del lenguaje. Entre 2017 y 2018 hubo una comunidad de abuso sexual basado en imágenes en Twitter. Al menos 329 usuarios se dedicaron y se auto describieron como cuentas sexualmente explícitas, vengativas, y en donde contenido sexual no consensual podía ser compartido de forma anónima. Ya con seguidores, la red comprende a más de 130,000 personas. Esta es una estimación conservadora, más cuentas podrían utilizar diferentes palabras clave, no tener ninguna descripción, o formar parte de comunidades privadas. Estos resultados sugieren que los consumidores de contenido de abuso sexual basado en imágenes son los principales responsables de su propagación. Abstract: This study aimed to explore the structure and content of an image-based sexual abuse user network on Twitter. For this purpose, Twitter profiles containing the word “Quemones” or "Nudes" were analyzed using network analysis, natural language processing techniques. Between 2017 and 2018 there was a community of image-based sexual abuse on Twitter. At least 329 users engaged in and self- described themselves as sexually explicit, vindictive accounts, and where nonconsensual sexual content could be shared anonymously. Already with followers, the network comprises more than 130,000 people. This is a conservative estimate; more accounts could use different keywords, have no description, or be part of private communities. These results suggest that consumers of image-based sexual abuse content are primarily responsible for its spread. Fuentes de Consulta: Allen, W. D. (2007). The Reporting and Underreporting of Rape. 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(2015). Connections between online harassment and offline violence among youth in Central Thailand. Child Abuse &amp; Neglect, 44, 159–169. https://doi.org/10.1016/j.chiabu.2015.04.001 Park, B., Wilson, G., Berger, J., Christman, M., Reina, B., Bishop, F., … Doan, A. (2016). Is Internet Pornography Causing Sexual Dysfunctions? A Review with Clinical Reports. Behavioral Sciences, 6(3), 17. https://doi.org/10.3390/bs6030017 Pina, A., Holland, J., &amp; James, M. (2017). The Malevolent Side of Revenge Porn Proclivity: Dark Personality Traits and Sexist Ideology. International Journal of Technoethics, 8(1), 30–43. https://doi.org/10.4018/IJT.2017010103 Powell, A., &amp; Henry, N. (2017). Sexual Violence in a Digital Age. Palgrave Macmillan. Powell, A., Henry, N., &amp; Flynn, A. (2018). Image-Based Sexual Abuse. In Routledge Handbook of Critical Criminology (2nd Edition, pp. 305–315). Routledge. Priebe, G., &amp; Svedin, C. G. (2012). 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Stepanova, Kristina V., Natalia M. Yakovleva, Alexander N. Kokatev та Håkan Pettersson. "Структура и свойства нанопористых анодных оксидных пленок на алюминиде титана". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, № 1 (2019): 135–45. http://dx.doi.org/10.17308/kcmf.2019.21/724.

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Работа посвящена обобщению результатов исследования анодирования алюминида титана (γ-TiAl) во фторсодержащих электролитах. Установлены оптимальные условия анодирования, приводящие к формированию самоорганизованных нанопористых анодных оксидных пленок (АОП) на поверхности образцов, сплава Ti-40 wt. % Al. Показано, что при оптимальных условиях образуются рентгеноаморфные оксидные пленки гетерогенного состава (Al2O3:TiO2 @ 1:1) с размерами пор в диапазоне от 40 до 80 nm. Полученные результаты свидетельствуют о перспективности применения анодного наноструктурирования порошков Ti-40 wt. % Al для получения фотокаталитически активных материалов с расширенным до видимого света спектральным диапазоном поглощения.&#x0D; &#x0D; &#x0D; ЛИТЕРАТУРА&#x0D; &#x0D; Wang Y., Ma X., Li H., Yin S., Sato T. Advanced Catalytic materials - Photocatalysis and Other Current Trends, 2016, vol. 12, pp. 337–357. https://doi.org/10.5772/61864&#x0D; Hashimoto K., Irie H., Fujishima A. Japanese Journal of Applied Physics, 2005, vol. 44, no. 12, pp. 8269–8285. https://doi.org/10.1143/jjap.44.8269&#x0D; Uddin Md.T., Engg M. Sc. Dr. Rer. Nat. Technical University of Darmstadt, 2014, 222 p. URL: https://d-nb.info/1061050335/04 (accessed 28.11.2018)&#x0D; Batzill M. Energy Environ. Sci., 2011, vol. 4, pp. 3275–3286. https://doi.org/10.1039/c1ee01577j&#x0D; Marschall R. Funct. Mater., 2014. vol. 24. pp. 2421–2440. https://doi.org/10.1002/adfm.201303214&#x0D; Ghicov A., Schmuki P. Commun., 2009, pp. 2791–2808. https://doi.org/10.1039/b822726h&#x0D; Li F., Zhao Y., Hao Y., Wang X., Liu R., Zhao D., Chen D. Journal of Hazardous Materials, 2012, vol. 239–240. pp. 118–127. https://doi.org/10.1016/j.jhazmat.2012.08.016&#x0D; Morris S. M., Horton J. A., Jaroniec M. Mesopor. Mater., 2010, vol. 128, pp. 180–186. https://doi.org/10.1016/j.micromeso.2009.08.018&#x0D; Ahmed M. A., Abdel-Messih M. F. Journal of Alloys and Compounds, 2011, vol. 509, pp. 2154–2159. https://doi.org/10.1016/j.jallcom.2010.10.172&#x0D; Pakmehr M., Nourmohammadi A., Ghashang M., Saffar-Teluri A. Journal of Particle Science and Technology, 2015, pp. 31–38. https://doi.org/22104/JPST.2015.76&#x0D; Pei J., Ma W., Li R., Li Y., Du H. Journal of Chemistry, 2015, pp. 1–7. https://doi.org/10.1155/2015/806568&#x0D; Il'in, A. A., Kolachev, B. A., Pol'kin, I. S. Titanovye splavy. sostav, struktura, svoistva [Titanium alloys. Composition, structure, properties]. Moscow, VILS-MATI Publ., 2009, 520 p. (in Russ.)&#x0D; Tsuchiya, H., Berger, S., Macak, J.M., Ghicov, A., Schmuki, P. Comm., 2007, vol. 9, pp. 2397–2402. https://doi.org/10.1016/j.elecom.2007.07.013&#x0D; Berger, S., Tsuchiya, H., Schmuki, P. Mater., 2008, vol. 20, pp. 3245–3247. https://doi.org/10.1021/cm8004024&#x0D; Stepanova K. V., Yakovleva N. M., Kokatev A. N., Pettersson Kh. zap. PetrGU. Seriya Estestvennye i tekhnicheskie nauki, 2015, vol. 147, no. 2, pp. 81–86. (in Russ.)&#x0D; Stepanova К. V., Yakovleva N. M., Kokatev А. N., Pettersson H. Journal of Surface Investigation. X-ray, Synchrotron and Neutron Techniques, 2016, vol. 10, no. 5, pp. 933– https://doi.org/10.1134/S102745101605013X&#x0D; Stepanova K. V. Diss. kand. tekh. nauk. Petrozavodsk, 2016, 162 p. (in Russ.)&#x0D; Yakovleva N. M., Kokatev A. N., Chupakhina E. A., Stepanova K. V., Yakovlev A. N., Vasil'ev S. G., Shul'ga A. M. Condensed Matter and Interphases, 2016, vol. 18, no. 1, pp. 6− URL: http://www.kcmf.vsu.ru/resources/t_18_1_2016_001.pdf (in Russ.)&#x0D; Kokatev A. N. Diss. kand. tekh. nauk. Petrozavodsk, 2013, 170 p.&#x0D; Savchenko O. I., Yakovleva N. M., Yakovlev A. N., Kokatev A. N., Pettersson Kh. Condensed Matter and Interphases, 2012, vol. 14, no. 2, pp. 243–249. URL: http://www.kcmf.vsu.ru/resources/t_14_2_2012_018.pdf (in Russ.)&#x0D; Canulescu S., Rechendorff K., Borca C.N., Jones N.C., Bordo K., Schou J., Pleth Nielsen L., Hoffmann S. V., Ambat R. Applied Physics Letters, 2014, vol. 104, pp. 121910(1–4). https://doi.org/10.1063/1.4866901&#x0D; Chen C., Liu J., Liu P., Yu B. Advances in Chemical Engineering and Science, 2011, vol. 1, pp. 9– https://doi.org/10.4236/aces.2011.11002&#x0D; Rashed M. N., El-Amin A. A. International Journal of Physical Sciences, 2007, vol. 2 (3), pp. 073–081. URL: http://www.academicjournals.org/IJPS (accessed 28.11.2018)&#x0D; Ivanov V. M., Tsepkov M. G., Figurovskaya V. N. Vestnik Moskovskogo universiteta. Seriya 2: Khimiya [Moscow University Chemistry Bulletin], 2010, vol. 65, 6, pp. 370-373. https://link.springer.com/article/10.3103%2FS0027131410060076&#x0D; Scuderi V., Impellizzeri G., Romano L., Scuderi M., Nicotra G., Bergum K., Irrera A., Svensson B.G., Privitera V. Nanoscale Research Letters, 2014, vol. 9, pp. 458–464. https://doi.org/10.1186/1556-276x-9-458 &#x0D; AbdElmoula M. Dr. Philosophy. Boston, 2011, 275 р.&#x0D; Lee K., Mazare A., Schmuki P. Rev., 2014, vol. 114, pp. 9385–9454. https://doi.org/10.1021/cr500061m&#x0D; Leyens C., Peters M. Titanium and Titanium Alloys. Fundamentals and Applications. Weinheim: WILEY-VCH Verlag GmbH &amp; Co. KGaA, 2003, 532 p.&#x0D; &#x0D;
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Roczo-Farkas, Susie, Carl D. Kirkwood, Julie E. Bines, and Australian Rotavirus Surveillance Group. "Australian Rotavirus Surveillance Program: Annual Report, 2016." Communicable Diseases Intelligence 41 (December 1, 2017): 455–71. https://doi.org/10.33321/cdi.2017.41.48.

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This report from the Australian Rotavirus Surveillance Program (ARSP) and collaborating laboratories Australia-wide, describes the rotavirus genotypes identified in children and adults with acute gastroenteritis during the period 1 January to 31 December 2016. During this period, 949 faecal specimens were referred for rotavirus G and P genotype analysis, of which 230 were confirmed as positive for wildtype rotavirus, and 184 were identified as rotavirus vaccine-like. Genotype analysis of the 230 samples from both children and adults revealed that G2P[4] was the dominant genotype in this reporting period nationally, identified in 29% of samples, followed by equine-like G3P[8] and G12P[8] (19% and 15% respectively). Genotype distribution remained distinct between States using RotaTeq® and Rotarix® vaccines. In RotaTeq® States, G12P[8] strains were more common, while G2P[4] and equine-like G3P[8] genotypes were more common in Rotarix® States and Territories. This report highlights the continued dominance of G12P[8] strains in RotaTeq® States and co-dominance of G2P[4] and equine-like G3P[8] in States and Territories using Rotarix®.
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El-Sherbiny, Ibrahim M., and Hugh D. C. Smyth. "Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications." Journal of Nanomaterials 2011 (2011): 1–13. http://dx.doi.org/10.1155/2011/910539.

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We have developed a novel spray gelation-based method to synthesize a new series of magnetically responsive hydrogel nanoparticles for biomedical and drug delivery applications. The method is based on the production of hydrogel nanoparticles from sprayed polymeric microdroplets obtained by an air-jet nebulization process that is immediately followed by gelation in a crosslinking fluid. Oligoguluronate (G-blocks) was prepared through the partial acid hydrolysis of sodium alginate. PEG-grafted chitosan was also synthesized and characterized (FTIR, EA, and DSC). Then, magnetically responsive hydrogel nanoparticles based on alginate and alginate/G-blocks were synthesized via aerosolization followed by either ionotropic gelation or both ionotropic and polyelectrolyte complexation using CaCl2or PEG-g-chitosan/CaCl2as crosslinking agents, respectively. Particle size and dynamic swelling were determined using dynamic light scattering (DLS) and microscopy. Surface morphology of the nanoparticles was examined using SEM. The distribution of magnetic cores within the hydrogels nanoparticles was also examined using TEM. In addition, the iron and calcium contents of the particles were estimated using EDS. Spherical magnetic hydrogel nanoparticles with average particle size of 811 ± 162 to 941 ± 2 nm were obtained. This study showed that the developed method is promising for the manufacture of hydrogel nanoparticles, and it represents a relatively simple and potential low-cost system.
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Zorluoğlu, Seraceddin Levent, İbrahim Hüdai Taşdemir, Abdulilah Ece, and Esma Kiliç. "A cooperative computational and experimental investigation on electrochemical behavior of metoprolol and its voltammetric determination." Canadian Journal of Chemistry 91, no. 10 (2013): 951–59. http://dx.doi.org/10.1139/cjc-2012-0531.

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The electrochemical behavior of metoprolol (MTP) was studied via experimental and computational approaches. Theoretical calculations were performed at the B3LYP/6-31+G(d)//AM1 level whereas experimental studies were carried out on a hanging mercury drop electrode (HMDE) and glassy carbon electrode (GCE). According to the computational results, both HOMO and LUMO of MTP were located at the phenyl ring. Hence, oxidation and reduction are expected to take place at the phenyl ring. Experimental studies on HMDE were based on reversible reduction at approximately –1.4 V and studies on GCE were based on irreversible oxidation at approximately 0.9 V versus Ag/AgCl (3 mol L−1 KCl) in Britton−Robinson buffer. Voltammetric methods with and without adsorptive stripping modes were developed. Proposed methods were successfully applied to tablet solutions and spiked human serum samples. Results are satisfactory with recovery values between 94.5% and 102.5% and a relative standard deviation lower than 6%.
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Ziegler, Julian O., Christoph Maas, Wolfgang Bernhard, Joerg Arand, Christian F. Poets, and Axel R. Franz. "Retrospective cohort analysis on pancreatic enzyme substitution in very low birthweight infants with postnatal growth failure." Archives of Disease in Childhood - Fetal and Neonatal Edition 103, no. 5 (2017): F485—F489. http://dx.doi.org/10.1136/archdischild-2017-313278.

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ObjectiveTo evaluate the effects of pancreatic enzyme substitution (PES) in selected very low birthweight (VLBW) infants with poor postnatal growth despite intensified nutritional support.DesignRetrospective historic cohort study with matched controls.SettingSingle level III neonatal intensive care unit.PatientsInfants with a gestational age at birth &lt;32 weeks and birth weight &lt;1500 g born between 1 January 2005 and 31 December 2014 (n=26) who received PES for restricted postnatal growth despite intensified enteral nutritional support in comparison with infants matched for birth weight, birth year, gestational and postnatal age (n=52).InterventionsPES 15–93 mg/g fat with enteral feeds.Main outcome measuresThe difference in SD score (SDS) differences for weight during the 7 days before and after onset of PES and weight gain in g/kg/d. Data are presented as median (P10–P90).ResultsGestational age was 26.6 (24.4–29.9) weeks in enzyme substituted versus 26.4 (24.7–29.9) weeks in matched controls, and birth weight was 648(420–950)g versus 685(453–949)g. SDS differences for weight improved after onset of PES by 0.18(−0.12 to 0.53) in PES infants versus −0.04(−0.31 to 0.44) in controls. Weight gain increased in the PES group from 13.6 (4.2–22.9) g/kg/day in the week before to 19.0 (10.9–29.1) g/kg/day in the week after the onset of PES. There was no difference in weight gain in substituted subgroups receiving formula/pasteurised human milk versus unpasteurised human breast milk or who had pancreatic-specific elastase-1 concentrations in stool &gt;200 µg/g versus≤200 µg/g. No adverse effects were noted.ConclusionsPES in selected VLBW infants with growth failure despite intensified enteral nutritional support was associated with a significant increase in weight gain in the first 7 days of PES.k
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Carter, Natalie A., Catherine E. Dewey, Ben Lukuyu, Delia Grace, and Cornelis F. M. de Lange. "Nutrient composition and seasonal availability of local feedstuffs for pigs in western Kenya." Canadian Journal of Animal Science 95, no. 3 (2015): 397–406. http://dx.doi.org/10.4141/cjas-2015-003.

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Carter, N. A., Dewey, C. E., Lukuyu, B., Grace, D. and de Lange, C. F. M. 2015. Nutrient composition and seasonal availability of local feedstuffs for pigs in western Kenya. Can. J. Anim. Sci. 95: 397–406. In this study, nutritional values and seasonal availability were estimated for 25 local feedstuffs for pigs in western Kenya, based on analyzed nutrient contents and a review of the literature. Characteristics considered included: crude protein (CP), neutral detergent fibre (NDF), acid detergent fibre (ADF), ether extract (EE), Ca, P, standardized total tract digestible (STTD) P, total Lys, standardized ileal digestible (SID) Lys (all as g kg−1 of DM), and digestible energy (DE) (kcal kg−1 DM). Contents of total Lys, SID lysine, STTD P, and DE were estimated. Overripe improved-variety avocado (Persea americana) had the greatest estimated DE (5280 kcal kg−1 DM) and EE content (521 g kg−1 of DM). Cattle rumen content had the greatest NDF content (664 g kg−1 of DM). Sun-dried fish (Rastrineobola argentea) had the greatest estimated STTD P content (13.5 g kg−1 of DM). Amaranthus spinosus L. had the greatest Ca content (26 g kg−1 of DM). Fresh cattle blood had the greatest CP and estimated SID Lys content (944 and 83.0 g kg−1 of DM, respectively). Feedstuffs availability periods are: March through May plus September and October; June through August; and November through February. Local feedstuffs of sufficient nutritional value for pigs are seasonally available. Estimated nutritional values may assist in diet formulation.
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Rahman, Mohammad L., Deepika Shrestha, Tsegaselassie Workalemahu, et al. "Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations." Journal of Clinical Endocrinology & Metabolism 104, no. 11 (2019): 5032–42. http://dx.doi.org/10.1210/jc.2018-02756.

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Abstract Objectives Maternal genetic risk of type 2 diabetes (T2D) can influence offspring birthweight through shared offspring genetic risk and by altering intrauterine glycemic status. The aim of this study was to estimate the independent effects of maternal and offspring genetic risk scores (GRSs) of T2D on offspring birthweight and the extent to which intrauterine glycemic traits mediate the effect of maternal GRSs on offspring birthweight. Design The study involved 949 mother–offspring pairs of African ancestry from the Hyperglycemia Adverse Pregnancy Outcome study. GRSs of T2D were calculated separately for mothers and offspring as the weighted sum of 91 T2D risk alleles identified in a genome-wide association study meta-analysis in African Americans. Linear regression models were fit to estimate changes in birthweight by quartiles of GRSs. Mediation analysis was implemented to estimate the direct and indirect effects of maternal GRS on offspring birthweight through cord blood C-peptide and maternal fasting and postchallenge glucose levels. Results Maternal and offspring GRSs were independently and differentially associated with offspring birthweight. Changes (95% CI) in birthweight across increasing quartiles of maternal GRSs were 0 g (reference), 83.1 g (6.5, 159.6), 103.1 g (26.0, 180.2), and 92.7 g (12.6, 172.8) (P trend = 0.041) and those of offspring GRSs were 0 (reference), −92.0 g (−169.2, −14.9), −64.9 g (−142.4, 12.6), and 2.0 g (−77.8, 81.7) (P trend = 0.032). Cord blood C-peptide mediated the effect of maternal GRS on offspring birthweight, whereas maternal postchallenge glucose levels showed additive effects with maternal GRS on birthweight. Conclusions Maternal and offspring GRSs of T2D were independently and differentially associated with offspring birthweight.
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Orzechowska, Zuzanna, Mariusz Mrózek, Wojciech Gawlik, and Adam Wojciechowski. "Preparation and characterization of AFM tips with nitrogen-vacancy and nitrogen-vacancy-nitrogen color centers." Photonics Letters of Poland 13, no. 2 (2021): 28. http://dx.doi.org/10.4302/plp.v13i2.1095.

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We demonstrate a simple dip-coating method of covering standard AFM tips with nanodiamonds containing color centers. Such coating enables convenient visualization of AFM tips above transparent samples as well as using the tip for performing spatially resolved magnetometry. Full Text: PDF ReferencesG. Binnig, C. F. Quate, C. Gerber, "Atomic Force Microscope", Phys. Rev. Lett. 56, 930 (1986). CrossRef F .J. Giessibl, "Advances in atomic force microscopy", Rev. Mod. Phys. 75, 949 (2003). CrossRef S. Kasas, G. Dietler, "Probing nanomechanical properties from biomolecules to living cells", Eur. J. Appl. Physiol. 456, 13 (2008). CrossRef C. Roduit et al., "Stiffness Tomography by Atomic Force Microscopy", Biophys. J. 97, 674 (2009). CrossRef L. A. Kolodny et al., "Spatially Correlated Fluorescence/AFM of Individual Nanosized Particles and Biomolecules", Anal. Chem. 73, 1959 (2001). CrossRef L. Rondin et al., "Magnetometry with nitrogen-vacancy defects in diamond", Rep. Prog. Phys. 77, 056503 (2014). CrossRef C. L. Degen, "Scanning magnetic field microscope with a diamond single-spin sensor", Appl. Phys. Lett. 92, 243111 (2008). CrossRef J. M. Taylor et al., "High-sensitivity diamond magnetometer with nanoscale resolution", Nat. Phys. 4, 810 (2008). CrossRef J. R. Maze et al., "Nanoscale magnetic sensing with an individual electronic spin in diamond", Nature 455, 644 (2008). CrossRef L. Rondin et al., "Nanoscale magnetic field mapping with a single spin scanning probe magnetometer", Appl. Phys. Lett. 100, 153118 (2012). CrossRef J. P. Tetienne et al., "Nanoscale imaging and control of domain-wall hopping with a nitrogen-vacancy center microscope", Science 344, 1366 (2014). CrossRef R. Nelz et al., "Color center fluorescence and spin manipulation in single crystal, pyramidal diamond tips", Appl. Phys. Lett. 109, 193105 (2016). CrossRef G. Balasubramanian et al., "Nanoscale imaging magnetometry with diamond spins under ambient conditions", Nature 455, 648 (2008). CrossRef P. Maletinsky et al., "A robust scanning diamond sensor for nanoscale imaging with single nitrogen-vacancy centres", Nat. nanotechnol. 7, 320 (2012). CrossRef L. Thiel et al., "Quantitative nanoscale vortex imaging using a cryogenic quantum magnetometer", Nat. nanotechnol. 11, 677 (2016). CrossRef F. Jelezko et al., "Single spin states in a defect center resolved by optical spectroscopy", Appl. Phys. Lett. 81, 2160 (2002). CrossRef M. W. Doherty et al., "The nitrogen-vacancy colour centre in diamond", Phys. Rep. 528, 1 (2013). CrossRef C. Kurtsiefer, S. Mayer, P. Zarda, H. Weinfurter, "Stable Solid-State Source of Single Photons", Phys. Rev. Lett. 85, 290 (2000). CrossRef A. Gruber, A. Dräbenstedt, C. Tietz, L. Fleury, J. Wrachtrup, C. Von Borczyskowski, "Scanning Confocal Optical Microscopy and Magnetic Resonance on Single Defect Centers", Science 276, 2012 (1997). CrossRef F. Dolde et al., "Electric-field sensing using single diamond spins", Nat. Phys. 7, 459 (2011). CrossRef K. Sasaki et al., "Broadband, large-area microwave antenna for optically detected magnetic resonance of nitrogen-vacancy centers in diamond", Rev. Sci. Instrum. 87, 053904 (2016). CrossRef A. M. Wojciechowski et al., "Optical Magnetometry Based on Nanodiamonds with Nitrogen-Vacancy Color Centers", Materials 12, 2951 (2019). CrossRef I. V. Fedotov et al., "Fiber-optic magnetometry with randomly oriented spins", Opt. Lett. 39, 6755 (2014). CrossRef
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Valverde-Moya, José A., and Alexander Varela-Mejías. "Cultivo comercial de camarones Litopenaeus vannamei en Costa Rica durante el niño 2015: incidencia de enfermedades." Revista de Investigaciones Veterinarias del Perú 29, no. 1 (2018): 188. http://dx.doi.org/10.15381/rivep.v29i1.14187.

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Se estudiaron los rendimientos de producción del camarón Litopenaeus vannamei en estanques del Golfo de Nicoya, Costa Rica, para evaluar el efecto de las enfermedades diagnosticadas durante el fenómeno de El Niño 2015. Se utilizaron dos sistemas de cultivo: tres ciclos cortos (CC) al año en fincas con baja incidencia de enfermedades y dos ciclos largos (CL) al año en las fincas más afectadas con episodios de altas mortalidades. La sobrevivencia fue menor en aquellas con 2 CL (35.3 ± 3.2%) con respecto a las de 3 CC (63.1 ± 3.2%). Se registró una relación inversa entre el peso promedio alcanzado a la cosecha y la densidad final de cultivo (20.3 ± 0.8 g en 2 CL y 15.2 ± 1.6 g en 3 CC) y una compensación en el crecimiento (1.29 ± 0.12 y 1.08 ± 0.10 g/semana en 2 CL y 3 CC, respectivamente). La producción final fue directamente proporcional a la sobrevivencia con un promedio de 717 ± 8 kg/ha en 2 CL y de 941 ± 53 kg/ha en 3 CC. La productividad se redujo prácticamente a la mitad en 2 CL (1434 kg/ha*año) con respecto a 3 CC (2823 kg/ ha*año). No se encontró un beneficio en la productividad al mantener los cultivos para lograr tallas más grandes con los sobrevivientes luego de eventos de mortalidad severas.
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Şimşek, Kaan, and Sarp Kaya. "Investigating Co and Fe Single-Atom (SA) Decorated NS-Doped Reduced Graphene Oxide (Co SA/NS-rGO, Fe SA/NS-rGO) Catalysts for NOx - to NH3 Pulsed Electroreduction." ECS Meeting Abstracts MA2024-01, no. 39 (2024): 2325. http://dx.doi.org/10.1149/ma2024-01392325mtgabs.

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Electrochemical NH3 production has attracted much attention due to its potential to compensate for and supplement the Haber-Bosch process that produces hundreds of billions of kg of NH3 annually.1 One of the proposed electrochemical pathways to produce NH3 is the N2 reduction reaction. However, this reaction suffers from a high bond dissociation energy of 945 kJ mol−1, low NH3 Faradaic efficiency (F.E.) at high overpotentials, and NH3 quantification problems, limiting the extent of its applications.2,3 On the other hand, other N-containing species, NO3 - and NO2 -, that are commonly found in sewages and agricultural water, hold great potential for electrochemical NH3 production owing to their high NH3 yield rate and F.E. as well as building a self-sustaining NH3 production cycle working tandem with denitrification processes.1,4 In this study, we investigated Co and Fe single-atom (SA) decorated NS-doped reduced graphene oxide (Co SA/NS-rGO and Fe SA/NS-rGO) catalysts for nitrate reduction reaction (NO3RR) and nitrite reduction reaction (NO2RR). Both materials have defect-rich properties owing to preserving the nature of doped graphene materials even after the metal incorporation. The presence of the layered structure of graphene and homogenous distribution of Fe and Co SAs in the doped graphene basal plane is shown through High-Resolution Scanning Transmission Electron Microscopy (HR-STEM) measurements. In addition to the Co and Fe SAs on the NS-rGO planes, SEM and X-ray Photoelectron Spectroscopy (XPS) investigations demonstrated that CoS and FeS could be simultaneously formed. We performed NO3RR and NO2RR experiments in 0.1 M KOH + 0.1 M KNO3 and 0.1 M KOH + 0.1 M KNO2 electrolytes with constant Ar purging in a glass H-Cell with a Nafion proton exchange membrane. We obtained NH3 with 65% F.E. at -0.4 V and a maximum of 2 mol s-1 molM -1 yield rate using Co SA/NS-rGO catalyst while with 60% F.E. at -0.5 V and 2.3 mol s-1 molM -1 yield rate using Fe SA/NS-rGO catalyst for NO3RR. Furthermore, the ∼10% NO2 - F.E. that is obtained for NO3RR experiments at -0.3 V and a significant increase in NH3 F.E. after -0.3 V for NO2RR indicates that NO3 - to NO2 - reduction takes place at this potential and our catalysts follow a two-step electron transfer mechanism. Moreover, linear sweep voltammetry (LSV) measurements indicated an onset potential of -0.4 V and -0.5 V for Co SA/NS-rGO and Fe SA/NS-rGO, respectively, for the NO3RR which are in excellent agreement with NO3RR F.E. results. We demonstrate that after prereduction at high negative potentials and with optimizations in experimental conditions, one can obtain &gt;80% NH3 F.E. for NO3RR. To further increase the NH3 yield, three different pulsed electroreduction studies such as applying a potential at (1) the open circuit potential (OCP), (2) NO2 - reduction potential, (3) Co2+ or Fe2+ red-ox potentials and NH3 reduction potentials for 1-5 s intervals were performed. On Co SA/NS-rGO, an increased NH3 F.E. of ∼100% at -0.4 V was obtained under pulsed conditions. Also, by modulating NO3 - to NO2 - conversion to more negative potentials by pulsed electroreduction, significantly higher NH3 F.E. values were obtained for both catalysts. The higher NH3 F.E. and lower overpotential of Co SA/NS-rGO compared to Fe SA/NS-rGO could be attributed to the CoS formation that is more stable than FeS. References: (1) Erisman, J. W.; Sutton, M. A.; Galloway, J.; Klimont, Z.; Winiwarter, W. How a Century of Ammonia Synthesis Changed the World. Nature Geosci 2008, 1 (10), 636–639. https://doi.org/10.1038/ngeo325. (2) Suryanto, B. H. R.; Du, H.-L.; Wang, D.; Chen, J.; Simonov, A. N.; MacFarlane, D. R. Challenges and Prospects in the Catalysis of Electroreduction of Nitrogen to Ammonia. Nat Catal 2019, 2 (4), 290–296. https://doi.org/10.1038/s41929-019-0252-4. (3) Andersen, S. Z.; Čolić, V.; Yang, S.; Schwalbe, J. A.; Nielander, A. C.; McEnaney, J. M.; Enemark-Rasmussen, K.; Baker, J. G.; Singh, A. R.; Rohr, B. A.; Statt, M. J.; Blair, S. J.; Mezzavilla, S.; Kibsgaard, J.; Vesborg, P. C. K.; Cargnello, M.; Bent, S. F.; Jaramillo, T. F.; Stephens, I. E. L.; Nørskov, J. K.; Chorkendorff, I. A Rigorous Electrochemical Ammonia Synthesis Protocol with Quantitative Isotope Measurements. Nature 2019, 570 (7762), 504–508. https://doi.org/10.1038/s41586-019-1260-x. (4) Duca, M.; Koper, M. T. M. Powering Denitrification: The Perspectives of Electrocatalytic Nitrate Reduction. Energy Environ. Sci. 2012, 5 (12), 9726–9742. https://doi.org/10.1039/C2EE23062C.
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Eisig, Jaime Natan, Tomás Navarro-Rodriguez, Ana Cristina Sá Teixeira, et al. "Standard Triple Therapy versus Sequential Therapy inHelicobacter pyloriEradication: A Double-Blind, Randomized, and Controlled Trial." Gastroenterology Research and Practice 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/818043.

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Aim. To compare 10-day standard triple therapy versus sequential therapy as first-line treatment in patients infected withH. pylori.Methods. One hundredH. pyloripositive patients (diagnosed by rapid urease test and histology), with average age of 47.2, M/F = 28/72, were randomized to receive either standard triple treatment (TT) as follows: lansoprazole 30 mg, clarithromycin 500 mg, and amoxicillin 1 g, b.i.d. for ten days, or sequential treatment (ST) as follows: lansoprazole 30 mg, amoxicillin and placebo 1.0 g b.i.d for the first five days, followed by lansoprazole 30 mg, clarithromycin 500 mg, and tinidazole 500 mg b.i.d, for the remaining five days. Eradication rates were determined 60 days after treatment by urease, histology, or13C-urea breath test.Results. In intention to treat (ITT) analysis, the rate ofH. pylorieradication in the TT and ST groups was the same for both regimens as follows: 86% (43/50), 95% CI 93,3 to 73.4%. In Per protocol (PP) analysis, the rate ofH. pylorieradication in the TT and ST groups was 87.8% (43/49), 95% CI 94,5 to 75.3% and 89.6% (43/48), 95% CI 95,8 to 77.3%, respectively.Conclusions. In Brazil, standard triple therapy is as equally effective as sequential therapy in eradicatingHelicobacter pyloripatients. This study was registered under Clinical Trials with numberISRCTN62400496.
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Díaz-López, Andrés, Blanca Ribot, Josep Basora, and Victoria Arija. "High and Low Haemoglobin Levels in Early Pregnancy Are Associated to a Higher Risk of Miscarriage: A Population-Based Cohort Study." Nutrients 13, no. 5 (2021): 1578. http://dx.doi.org/10.3390/nu13051578.

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To evaluate whether women with anaemia or high haemoglobin (Hb) in early pregnancy would be at higher risk of miscarriage, this population-based cohort study involved 9453 women whose pregnancies were monitored at primary care centres between 2007 and 2012. The computerised clinical histories were used to collect: Hb measurements (up to 14 weeks of gestation), miscarriage before or by 24 weeks of gestation, and other maternal characteristics. The relation between anaemia (Hb &lt; 110 g/L), normal Hb (110–140 g/L, reference), and high Hb concentrations (≥140 g/L) with miscarriage were expressed as adjusted OR with 95%CI. Restricted cubic spline models were applied to evaluate the dose-response relationships. A total of 520 (5.5%) women were recorded as having a miscarriage. The rate of miscarriage in anaemia, normal Hb, and high Hb concentrations was 8.4%, 5.1%, and 10.2%, respectively. Compared with women with normal Hb at the first trimester, the multivariable-adjusted OR for miscarriage was 2.11 (95%CI, 1.38–3.21) for women with anaemia and 1.83 (95%CI, 1.29–2.58) for women with high Hb. Hb concentrations showed a U-shaped association with miscarriage, with the lowest incidence among women with Hb of 120–130 g/L. These data highlight the importance of considering anaemia and high Hb levels in early pregnancy as harmful indicators for miscarriage.
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Buitenhuis, E. T., W. K. W. Li, D. Vaulot, et al. "Picophytoplankton biomass distribution in the global ocean." Earth System Science Data Discussions 5, no. 1 (2012): 221–42. http://dx.doi.org/10.5194/essdd-5-221-2012.

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Abstract. The smallest marine phytoplankton, collectively termed picophytoplankton, have been routinely enumerated by flow cytometry since the late 1980s, during cruises throughout most of the world ocean. We compiled a database of 40 946 data points, with separate abundance entries for Prochlorococcus, Synechococcus and picoeukaryotes. We use average conversion factors for each of the three groups to convert the abundance data to carbon biomass. After gridding with 1° spacing, the database covers 2.4% of the ocean surface area, with the best data coverage in the North Atlantic, the South Pacific and North Indian basins. The average picophytoplankton biomass is 12 &amp;amp;pm; 22 μg C l−1 or 1.9 g C m−2. We estimate a total global picophytoplankton biomass of 0.53–0.74 Pg C (17–39% Prochlorococcus, 12–15% Synechococcus and 49–69% picoeukaryotes). Future efforts in this area of research should focus on reporting calibrated cell size, and collecting data in undersampled regions.
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Subba, Reddy K.V, and G. Simhachalam. "Dietary Aqua Fix Effectively Alters the Qualitative Protein Profile in the Head Kidney." Biolife 10, no. 4 (2022): 16–21. https://doi.org/10.5281/zenodo.7286178.

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<strong>Abstract</strong> The qualitative protein profile in head kidney of 6, 9 and 12 months old <em>Labeo rohita</em> was investigated by feeding with a diet mixed with an immunomodulator, Aqua Fix. 6 (group A), 9 (group B), and 12 (group C) months old fish (12-15 g wt.; 12 fish in each group) were fed with a diet mixed with Aqua Fix @ 50 mg/100 g of feed for 4 days.&nbsp; Another 3 groups (a, 6 months; b, 9 months; and c, 12 months) of same weight (12 fish in each group) were fed with a normal diet to act as controls for comparison.&nbsp; Head kidney showed significant alteration (with low and high molecular weight proteins) in the qualitative protein profile (analyzed by SDS page analysis), on day 1, 4, 7, 15 and 30 of experiment in all the three groups of 6 (group A), 9 (group B) and 12 (group c) months old fish.&nbsp; These results determine the effect of Aqua Fix in modulating the immune system of fish with regard to the marked changes in the profile of proteins. <strong>Keywords:</strong> Rohu<em>.</em> Aqua Fix, head kidney, qualitative proteins <strong>References</strong> Ashraf, M., Ayub, M. and Rauf, A. 2008. Effect of different feed ingredients and low temperature on diet acceptability, growth and survival of <em>Mrigal, Cirrhinus mrigala </em>fingerlings. Pakistan J. Zool. 40(2): 83-90. Delbarre-Ladrat, C., Cheret, R., Taylor, R. and Verrez-Bagnis, V. 2006. Trends in postmortem aging in fish: understanding of proteolysis and disorganization of the myofibrillar structure. Crit. Rev. Food Sci. Nutr. 46: 409-421. Demir, O., Gulle, I., Gumos, E., Kucuk, F., Gunlu, A. and Kepenek, K. 2010. Some reproductivefeatures of brown trout (Salmo truta macrostigma Dumeril, 1858) and its larval development under culture conditions. <em>Pak. Vet. J</em>. 30(4): 223-226. Demir, O., Gunlu,A., Kucuk, F., Gulle, I. and Gumus, E. 2011. Analysis of sarcoplasmic proteins in natural populations of mountain trout (<em>Salmo trutta macrostigma </em>Dumeril, 1858) with SDS-PAGE. Afri. J. Biotechnol. 10(55): 11758-11763. Fock, U. and Hinssen, H. 2002. Nebulin is a thin filament protein of the cardiac muscle of the agnathans. J. Muscle Research and Cell Motility. 23(3): 205-213. Gangwar, G., Rajesh Singh, Rao, A.P. and Tewari, S.C. 2007.Changes in biochemical composition of muscles of Indian major carp <em>Labeo rohita</em> (Ham.) in influence of age. The Asian J. Ani. Sci. 2(1 and 2): 46-48. Geri, G. Poli, B.M., Gualtieri, M.,Lupi, P. and Parisi, G. 1995.Body traits and chemical composition of muscles in the common carp (<em>Cyprinus carpio</em>) as influenced by age and rearing environment. Aquaculture, 129: 329-330. Gomez Guillen, M.C., Montero, P., Hurtado, O. and Borderias, A. 2000. Biological characteristics affect the quality of farmed Atlantic salmon and smoked muscle. J. Food Sci. 65(1): 53-60. Islam, M.T., Rashid, M.M. and Mostafa, K. 2008. Histopathological studies of experimentally infected shing, <em>Heteropneustes fossilis </em>with <em>Aeromonas hydrophila </em>bacteria. Progress. Agric. 19(1): 89-96. Jitender Kumar, J., Pal, K., Devivaraprasad Reddy, A., Sahu, N.P., Venkateshwarlu, G. and Vardia, H.K. (2012). Fatty acids composition of some selected Indian fishes. <em>African J. Basic Appl. Sci</em>. 4(5): 155-160 Ladrat, C., Chaplet, M., Verrez-Bagnis, V., Noel, J. and Fleurence, J. 2000. Neutral calcium-activated proteases from European sea bass (<em>Dicentrarchus labrax </em>L.) muscle: Polymorphism Biochem. Stud. Comp. Biochem. Physiol. 125B: 83-95. Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophase T4 Nature. 227: 680-685. Li, M.H., Bosworth, B.G. and Robinsson, E.H. 2000. Effect of dietary protein concentration on growth and processing yield of channel catfish (<em>Ictalurus punctatus</em>). J. World Aquaculture. Soc. 31: 592-598. Magnodottir, B. 2010. Immunological control of fish diseases. J. Mar. Biotechnol. 12: 361-379. Mahaboob, S., Farooq, M., Mahmood, D., Nasir, N., Sultana, S., Choudhry, A.S., Al-Akel, A.S., Al-Balawi, H.F.A., Al-Misned, F. and Al-Ghanim, K.A. (2012). Phylogenetic relationship of cultured and wild <em>Labeo rohita</em> and <em>Cirrhinus mrigala</em> based on muscle proteins profile in different weight groups. A new tool in phylogenetic analysis. <em>Int. J. Food. Prop</em>. 25: 949-960. Manoj, C.K., Mohankumaran, Nair, C., Patel, M.B. and Salin, K.R. 2010.Haematobiochemical and histopathological changes in <em>Labeo rohita</em> infected with <em>Aeromonas hydrophila</em> by immersion challenge. Fishery Technol. 47(2): 151-160. Mathew, S. and Prakash, V. 2006.Effect of calcium salts on the properties of proteins from oil sardine (<em>Sardinella longiceps</em>) during frozen storage. J. Food Sci., 71: 178-183. Mitsuhashi, T., Kasai, M. and Hatae, K. 2002. Detection of giant myofibrillar proteins connection and nebulin in fish meat by electrophoresis in 3-5 gradient sodium dodecyl sulfate polyacrylamide slab gels. J. Agric. Food Chem., 50(26): 7499-7503. Montowska, M. and Pospiech, E. 2007.Species identification of meat by electrophoretic methods. Acta Sci. Pol. Technol. Aliment., 6(1): 5-16. Mostofa, K., Islam, M.T., Sabur, M.A. and Rashid, M.M. 2008. Experimental pathogenesis of <em>Aeromonas hydrophila</em> bacterium in stinging catfish <em>Heteropneustes fossilis</em>. Bangladesh J. Fish. Res., 12(1): 27-33. Okagaki, T., Takami, M., Hosokawa, K., Yano, M., Fujime, S.H. and Ooi, A. 2005. Biochemical properties of ordinary and dark muscle myosine from carp skeletal muscle. J. Biochem., 138: 255-262. Plumb, J.A. and Hanson, L.A. 2011. Health maintenance and principal microbial diseases of cultured fishes. 3<sup>rd</sup> Edition, Wiley, Blackwell, Ames. Press, C. and Evensen, M.c.L.ϕ. 1999. The morphology of the immune system in teleost Fishes. Fish &amp; Shellfish Immunology. 9: 309-318. Rahman, M.H., Suzuki, S. and Kawai, K. 2001.The effect of temperature on <em>Aeromonas hydrophila</em> infection in gold fish, <em>Carassius auratus,</em> J. Appl. Icthyol. 17: 282-285. Sahoo, P.K. and Mukherjee, S.C. 2003. Immunomodulation by dietary vitamin C in healthy and aflatoxin B1-induced immunocompromised rohu (<em>Labeo rohita</em>). Comp. Immunol. Microbiol. Infect. Dis. 26: 65-76. Sahoo, P.K. and Mukherjee, S.C. 2002.The effect of dietary immunomodulation upon <em>Edwardsiella tarda</em> vaccination in healthy and immunocompromised Indian major carp (<em>Labeo rohita</em>). Fish &amp; Shellfish Immunol. 12: 1-16. Sahoo, P.K., Kumari, J. and Mishra, B.K. 2005. Non-specific immune responses in juveniles of Indian major carps. J. Apl. Ichtyol. 21: 151-155. Salim, M. (2006). Role of fish as food to human nutrition. International Conference on &ldquo;Solving Problems of Fresh Water Fish Farming in Pakistan&rdquo;, p.20. November 27-28, UVAS, Lahore, Pakistan. Sarkar, M.G.A., Chowdhury, B.M.R., Faruk, M.A.R. Uddin, M.N. and Islam, M.J. 2000. Effect of water temperature on the infectivity of <em>Aeromonas hydrophila</em> isolates. Bangladesh J. Fish. 23(2): 99-105. Sultana, S., Zahra, A., Sultana, T., Al-Ghanim, K.A. and Mahboob, S. 2016.Effect of different artificial feeds formulated from local ingredients on the meat quality of Indian major carps. The J. Animal and Plant. Sci. 26(4): 1140-1145. Tanriverdi, E.A., Yilmaz, M., Koc, E., Akgul, A. and Ersan, Y. 2016.The effect of dimethoate on <em>Capoeta capoeta </em>(Guldenstaedt 1773) and the protective effect of ascorbic acid.Fres. Env. Bul. 25: 5974-5979. Vidyasagar Reddy, G. and Vijaya, Ch. (2014). Protein profile of selected commercial freshwater fishes of Nellore, India, <em>Biotechnol</em>. 3: 1-3.
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Múzquiz de la Garza, Ana Rocío, Mireya Tapia-Salazar, Maribel Maldonado-Muñiz, et al. "Nutraceutical Potential of Five Mexican Brown Seaweeds." BioMed Research International 2019 (December 19, 2019): 1–15. http://dx.doi.org/10.1155/2019/3795160.

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In search of pharmaceutically active products to control type 2 diabetes, five brown seaweeds (Silvetia compressa, Cystoseira osmundacea, Ecklonia arborea, Pterygophora californica, and Egregia menziesii) from the Northwest Mexican Pacific coast were investigated. Proximate composition and total polyphenol content (TPC) as phloroglucinol equivalents (PGE) were determined for the five seaweed powders and their respective hydroethanolic (1 : 1) extracts. Extracts were screened for their radical scavenging activity (DPPH and ORAC) and glycosidase inhibitory activity. HPLC-DAD, HPLC-MS-TOF, and ATR-FT-IR methodologies were used to identify the most abundant phlorotannins and sulfated polysaccharides in the extracts. Hydroethanolic extracts contained minerals (17 to 59% of the dry matter), proteins (4 to 9%), ethanol-insoluble polysaccharides (5.4 to 53%), nitrogen-free extract (NFE) (24.4 to 70.1%), lipids (5 to 12%), and TPC (2.6 to 47.7 g PGE per 100 g dry extract). S. compressa and E. arborea dry extracts presented the lowest ash content (26 and 17%, respectively) and had some of the highest phenolic (47.7 and 15.2 g PGE per 100 g extract), NFE (57.3 and 70.1%), and soluble polysaccharide (19.7 and 53%) contents. S. compressa and E. arborea extracts had the highest antioxidant activity (IC50 DPPH 1.7 and 3.7 mg mL−1; ORAC 0.817 and 0.801 mmol Trolox equivalent/g extract) and the highest α-amylase and α-glucosidase inhibitory capacities (IC50 940 and 1152 μg mL−1 against α-amylase and 194 and 647 μg mL−1 against α-glucosidase). The most abundant phlorotannins identified in the extracts were phloretol, fucophloroethol, and two- and three-phloroglucinol unit (PGU) phlorotannins. Laminarin, fucoidan, and alginate were among the sulfated polysaccharides identified in the extracts. The bioactivities of S. compressa and E. arborea extracts were mainly related with their contents of three PGU phlorotannins and sulfated polysaccharides (e.g., fucoidan, laminarin, and alginate). These results suggest S. compressa and E. arborea are potential candidates for food products and nutraceutical and pharmaceutical preparations, and as additives for diabetes management.
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Szabó, F., I. Füller, A. Fördős, and S. Bene. "Weaning results of beef Hungarian Fleckvieh calves 1. Environmental factors." Archives Animal Breeding 53, no. 1 (2010): 18–25. http://dx.doi.org/10.5194/aab-53-18-2010.

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Abstract. Weaning performance of 7 032 purebred Hungarian Fleckvieh calves (3 650 male and 3 382 female) born between 1981 and 2003 from 1 452 cows mated with 113 sires were analysed in two farms. The aim of the study was to evaluate the effect of environmental factors on weaning traits. Farm, age of cows, year of birth, season of birth and sex of calves as fixed, while sire as a random effect was treated. Data were analysed with HARVEY’s (1990) Least Square Maximum Likelihood Computer Program. The overall mean value and standard error of weaning weight, preweaning daily gain and 205-day weight were 214 ± 3.01 kg, 980 ± 17.31 g/day and 236 ± 3.40 kg, respectively. The mean age of the analysed calves was 181 ± 33 days. The results of the examination show that weaning weight, preweaning daily gain and 205-day weight increased as far as the 6 year age cows (the maximum were 226 ± 3.13 kg, 1 049 ± 17.89 g/day, 251 ± 3.54 kg). As for the season effect the calves born in summer were smaller (208 ± 3.12 kg, 946 ± 17.84 g/day and 230 ± 3.52 kg) than that of born in the other seasons (P&lt;0.001). The male calves were heavier than females, the difference was 12 kg, 50 g/day, 16 kg, respectively (P&lt;0.001). The best year was 1985, the worst 2000.
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35

Vázquez, Horacio, María de la Paz Temprano, Emilia Sugai, et al. "Prevalence of Celiac Disease and Celiac Autoimmunity in the Toba Native Amerindian Community of Argentina." Canadian Journal of Gastroenterology and Hepatology 29, no. 8 (2015): 431–34. http://dx.doi.org/10.1155/2015/927458.

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BACKGROUND: Celiac disease (CD) is mostly recognized among subjects with a Caucasian ethnic ancestry. No studies have explored conditions predisposing Amerindians to CD.OBJECTIVE: To prospectively assess environmental, genetic and serological conditions associated with CD among members of the Toba native population attending a multidisciplinary sanitary mission.METHODS: An expert nutritionist determined daily gluten intake using an established questionnaire. Gene typing for the human leukocyte antigen (HLA) class II alleles was performed on DNA extracted from peripheral blood (HLA DQ2/DQ8 haplotype). Serum antibodies were immunoglobulin (Ig) A tissue transglutaminase (tTG) and the composite deamidated gliadin peptides/tTG Screen test. Positive cases were tested for IgA endomysial antibodies.RESULTS: A total of 144 subjects (55% female) were screened. The estimated mean gluten consumption was 43 g/day (range 3 g/day to 185 g/day). Genetic typing showed that 73 of 144 (50.7%) subjects had alleles associated with CD; 69 (94.5%) of these subjects had alleles for HLA DQ8 and four had DQ2 (5.5%). Four and six subjects had antibody concentrations above the cut-off established by the authors’ laboratory (&gt;3 times the upper limit of normal) for IgA tTG and deamidated gliadin peptides/tTG screen, respectively. Four of these had concomitant positivity for both assays and endomysial antibodies were positive in three subjects who also presented a predisposing haplotype.CONCLUSION: The present study was the first to detect CD in Amerindians. The native Toba ethnic population has very high daily gluten consumption and a predisposing genetic background. We detected subjects with persistent CD autoimmunity and, at least, three of them fulfilled serological criteria for CD diagnosis.
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Buitenhuis, E. T., W. K. W. Li, D. Vaulot, et al. "Picophytoplankton biomass distribution in the global ocean." Earth System Science Data 4, no. 1 (2012): 37–46. http://dx.doi.org/10.5194/essd-4-37-2012.

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Abstract. The smallest marine phytoplankton, collectively termed picophytoplankton, have been routinely enumerated by flow cytometry since the late 1980s during cruises throughout most of the world ocean. We compiled a database of 40 946 data points, with separate abundance entries for Prochlorococcus, Synechococcus and picoeukaryotes. We use average conversion factors for each of the three groups to convert the abundance data to carbon biomass. After gridding with 1° spacing, the database covers 2.4% of the ocean surface area, with the best data coverage in the North Atlantic, the South Pacific and North Indian basins, and at least some data in all other basins. The average picophytoplankton biomass is 12 &amp;amp;pm; 22 μg C l−1 or 1.9 g C m−2. We estimate a total global picophytoplankton biomass of 0.53–1.32 Pg C (17–39% Prochlorococcus, 12–15% Synechococcus and 49–69% picoeukaryotes), with an intermediate/best estimate of 0.74 Pg C. Future efforts in this area of research should focus on reporting calibrated cell size and collecting data in undersampled regions. http://doi.pangaea.de/10.1594/PANGAEA.777385
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Maly, Jan, Iva Burianova, Veronika Vitkova, Eva Ticha, Martina Navratilova, and Eva Cermakova. "Preterm human milk macronutrient concentration is independent of gestational age at birth." Archives of Disease in Childhood - Fetal and Neonatal Edition 104, no. 1 (2018): F50—F56. http://dx.doi.org/10.1136/archdischild-2016-312572.

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ObjectiveTo evaluate the amount of macronutrients in aggregate of human milk samples after preterm delivery during the first 2 months of lactation.MethodsAnalysis of the donated single milk samples, gained by complete emptying of the whole breast at the same daytime between 24+0 and 35+6 gestational age (GA), was designed as prospective observational cohort trial. Two milk samples were analysed every postnatal week up to the discharge from the hospital, week 9 or loss of lactation. 24-Hour milk collection was not done. Analysis was performed using the MIRIS Human Milk Analyser (MIRIS AB, Uppsala, Sweden).ResultsA set of 1917 human milk samples donated by 225 mothers after preterm labour was analysed. Group A (24–30 GA) contains 969 milk samples; group B (31–35 GA) contains 948 milk samples. No difference in milk composition between the groups was identified. Median of true protein content decreased from 1.6 g/dL in group A and 1.5 g/dL in group B in the first week of life, to 1.1 g/dL in both groups at the end of week 3, and then remained stable up to week 9. Content of carbohydrates and fat was stable during the whole observation, with interindividual differences.ConclusionHuman milk does not differ as a function of degree of prematurity. Protein content of preterm human milk is low and decreases during the first 3 weeks of lactation. Recommended daily protein intake cannot be achieved with routine fortification in majority of milk samples.
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Zhao, Jianghong, Jia Li, Qiaohong Lai, and Yanping Yu. "Combined use of gap-PCR and next-generation sequencing improves thalassaemia carrier screening among premarital adults in China." Journal of Clinical Pathology 73, no. 8 (2020): 488–92. http://dx.doi.org/10.1136/jclinpath-2019-206339.

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AimsThalassaemia is one of the most common genetics disorders in the world, especially in southern China. The aim of the present study was to investigate the feasibility of combining the gap-PCR and next-generation sequencing (NGS) for thalassaemia carrier screening in the Chinese population.MethodsBlood samples were obtained from 944 prepregnancy couples; thalassaemia carrier screening was performed by using a routine haematological method and a combination of gap-PCR and NGS method.ResultsWe found that the α thalassaemia carrier rate was 11% (207/1888); the β thalassaemia carrier rate was 3.7% (70/1888); the composite α thalassaemia and β thalassaemia carrier rate was 0.4% (8/1888). We also identified seven novel mutations, including HBA1: c.412A&gt;G, −50 (G&gt;A), HBB: c.*+129T&gt;A, HBB: c.-64G&gt;C, HBB: c.-180G&gt;C, HBB: c.*+5G&gt;A and HBB: c.-113A&gt;G. By comparing the combined gap-PCR and NGS method, the MCV+MCH and HbA2 detection strategy showed a lower sensitivity of 61.05% (105/172) and a higher missed diagnosis ratio of 38.95% (67/172) for α thalassaemia mutations. The sensitivity was improved with the MCV+MCH and HbA2 detection screen when compared with MCV+MCH detection for β thalassaemia (98.51% vs 85.90%).ConclusionsOur study suggests the combined gap-PCR and NGS method is a cost-effective method for the thalassaemia carrier screening, particularly for the α thalassaemia mutation carriers.
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39

Tait, Michael B. "Neither Jew Nor Greek:A Contested Identity, James D. G. Dunn, Eerdmans, 2015 (ISBN 978-0-8028-3933-6), xiv + 946 pp., hb $60." Reviews in Religion & Theology 23, no. 3 (2016): 290–94. http://dx.doi.org/10.1111/rirt.12677.

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40

Mehra, Pooja, Surabhi Palkimas, Laura Parsons, et al. "Multidisciplinary Implementation of an Iron Deficiency Anemia in Pregnancy Treatment Protocol." Blood 134, Supplement_1 (2019): 2121. http://dx.doi.org/10.1182/blood-2019-123902.

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Background: Anemia in pregnancy increases the need for blood transfusion during and after delivery and is associated with an increased risk of maternal and fetal mortality, therefore preventing maternal anemia may improve outcomes. Iron deficiency is the most common pathologic cause of anemia in pregnancy and is estimated to affect about 30% of pregnant women in the third trimester in the US. The baseline peripartum blood transfusion rate at our institution is 3.2%. Historically, patients who may have benefited from intravenous (IV) iron were continued on oral iron and subsequently delivered with persistent iron deficiency anemia. If identified to need IV iron, these patients were usually referred to a hematologist. However, in the absence of a structured protocol, referral was provider-dependent. Objective: We formed a multidisciplinary work group consisting of members from the departments of Hematology, Obstetrics, Pharmacy, Nursing, and Blood Bank to reduce peripartum blood transfusions by developing a process to manage pregnant patients with iron deficiency anemia. The treatment algorithm utilized at our institution was adapted from "How I treat anemia in pregnancy: iron, cobalamin, and folate" (Achebe &amp; Gafter-Gvili, 2017), which recommends IV iron for hemoglobin less than 11 g/dL and ferritin less than 30 µg/dL in the third trimester and for hemoglobin less than 10.5 g/dL and ferritin less than 30 µg/dL in the second trimester along with recommendations for iron repletion in the first trimester. The primary endpoint was the utilization of blood transfusion. Secondary endpoints included an increase in maternal hemoglobin after treatment and evaluating the safety of IV ferric carboxymaltose as measured by side effects and frequency of hypophosphatemia. Five months after initiation of the IV iron recommendations, we performed an audit to assess its use. Methods: A retrospective IRB-approved chart review of anemic, iron-deficient pregnant women who received IV ferric carboxymaltose from 1/30/19 - 6/30/19 was performed. Thirty-six patients were identified and their charts were reviewed to determine the hemoglobin and ferritin levels prior to IV iron, the number of IV iron infusions received with any side effects, phosphorus levels on days of IV iron, hemoglobin level after IV iron, and need for peripartum blood transfusion. Results: Of the 36 patients who received IV iron for anemia in pregnancy, post-IV iron hemoglobin and blood transfusion information was only available for 26 patients. The remaining 10 patients had not delivered as yet or had delivered at another institution so data were not available. Of these 26 patients, the median age was 26.0 years and all received IV iron during their third trimester. No patients required a blood transfusion peripartum. The average hemoglobin prior to IV iron was 9.3 g/dL and the average hemoglobin after 1-2 IV iron infusions was 11.3 g/dL, an increase of 2.0 g/dL across the total group (Figure 1) (p&lt;0.0001). Of these 26 patients, 7 patients received 1 dose of IV iron and 2 patients experienced heartburn or nausea during or soon after the IV iron infusion. Phosphorus levels were checked in 24 patients and 6 experienced hypophosphatemia with no attributable side effects. No patient experienced a serious adverse effect or reaction requiring discontinuation of IV iron therapy. Conclusion: Results from the first 5 months of this project suggest using a standardized iron deficiency anemia treatment protocol including IV iron to reduce the need for peripartum blood transfusion and increase hemoglobin levels. Additionally, our data suggest IV ferric carboxymaltose is well-tolerated in these patients. These results also support using multi-professional teams to improve the quality of healthcare delivery to pregnant patients with iron deficiency anemia. We have created an IRB-approved database to study more patient-centered postpartum outcomes such as quality of life among IV iron recipients as well as lactation rates and fetal outcomes. We plan to expand this strategy to other patients who have a predictable and likely preventable need for intermittent blood transfusion, such as patients with chronic gynecologic blood loss. Reference: Achebe, M. M., &amp; Gafter-Gvili, A. (2017). How I treat anemia in pregnancy: iron, cobalamin, and folate. Blood, 129(8), 940-949. https://doi.org/10.1182/blood-2016-08-672246. Disclosures Davidson: ABIM: Other: American Board of Internal Medicine.
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CHANNAGOUDA, R. F., H. B. BABALAD, and S. P. DINESHKUMAR. "Effect of organic manures, green leaf manures, liquid organic manures and micronutrients on yield and economics of cotton (Gossypium spp.)." Indian Journal of Agricultural Sciences 85, no. 10 (2015): 1273–78. http://dx.doi.org/10.56093/ijas.v85i10.52247.

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A field study was carried out at Main Agricultural Research Station (MARS), Dharwad during kharif 2010-11 and 2011-12 to study the effect of organic manures and micronutrients on cotton. The results of the two years pooled data revealed that, application of enriched compost (EC) (1/3) + vermicompost (VC) (1/3) + gliricidia leaf manure (GLM) (1/3) equivalent to recommended dose of fertilizer (5 tonnes/ha FYM) recorded significantly higher kapas yield (1 944 kg/ha) and mean boll weight (4.57 g) over EC (1/3) + VC (1/3) + GLM (1/3) equivalent to recommended dose of nitrogen. Foliar spray of panchagavya @ 5% recorded significantly higher kapas yield (2 038 kg/ha) and mean boll weight (4.76 g) over foliar spray of bio-digester @ 20% (1 874 kg/ha). Among the organic treatment combinations, combined application of EC (1/3) + VC (1/3) + GLM (1/3) equivalent to RDF with foliar spray of panchagavya @ 5% recorded significantly higher kapas yield (1 999 kg/ha) and mean boll weight (4.70 g) over other organic combinations. Application of EC (1/3) + VC (1/3) + GLM (1/3) equivalent to RDF recorded significantly higher gross returns, net returns and B:C ratio (Rupees 110380, 77335/ha and 3.34, respectively) over other manurial treatments. The foliar spray of panchagavya @ 5% recorded significantly higher gross returns, net returns and B:C ratio (Rupees 108542, 76048 ha and 3.34, respectively) over foliar spray of bio-digester @ 20%. Among the treatment combinations, combined application of EC (1/3) + VC (1/3) + GLM (1/3) equivalent to RDF with foliar spray of panchagavya @ 5% recorded significantly higher gross returns, net returns and B:C ratio (Rupees 113574, 80199/ha and 3.40, respectively) over EC (1/3) + VC (1/3) + GLM (1/3) equivalent to RDN with foliar spray of bio-digester @ 20%. Higher yield, yield parameters and economics can be obtained in cotton with combined application of EC (1/3) + VC (1/3) + GLM (1/3) equivalent to RDF with foliar spray of panchagavya @ 5%.
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CALHOUN, STEPHEN, LAURIE POST, BENJAMIN WARREN, STERLING THOMPSON, and ANN ROGERS BONTEMPO. "Prevalence and Concentration of Salmonella on Raw Shelled Peanuts in the United States." Journal of Food Protection 76, no. 4 (2013): 575–79. http://dx.doi.org/10.4315/0362-028x.jfp-12-322.

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Recalls and/or outbreaks associated with Salmonella contamination in peanut-containing products were reported over the past several years. There are very limited data available on the prevalence and concentration of Salmonella on raw shelled peanuts in the United States. The objectives of this study were to estimate the prevalence of Salmonella on raw shelled peanuts in the United States and to estimate that concentration of Salmonella. Samples of Runner- and Virginia-type raw shelled peanuts from the 2008, 2009, and 2010 crop years were proportionately sampled from each growing region, based on 2007 production volume. Of 944 raw shelled peanut samples (375 g each), 22 (2.33%) were positive for Salmonella by the VIDAS Salmonella assay. Salmonella serovars identified in this study included Agona, Anatum, Braenderup, Dessau, Hartford, Meleagridis, Muenchen, Rodepoort, Tennessee, and Tornow. The concentration levels of Salmonella in positive samples, as determined by a most-probable-number assay, were &amp;lt;0.03 to 2.4 MPN/g. These data will be useful when designing and validating processes for the reduction or elimination of Salmonella in peanuts and/or peanut-containing products.
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Wildenboer, Johan. "JOSHUA 24: SOME LITERARY AND THEOLOGICAL REMARKS." Journal for Semitics 24, no. 2 (2017): 484–502. http://dx.doi.org/10.25159/1013-8471/3465.

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Achenbach, R 2005. Pentateuch, Hexateuch und Enneateuch. Eine Verhältnisbestimmung, ZAR 11:122–154. Albertz, R 2007. Die kanonische Anpassung des Johuabuches. Ein Neubewertung seiner sog.”Priesterschriftelike Texte”, in Römer and Schmid 2007:199–217. Aurelius, E 2003. Zukunft jenseits des Gerichts: Eine redaktionsgeschichltliche Studie zumEnneateuch. BZAW 319. Berlin: de Gruyter. Barrick, W B &amp; Spencer, J R (eds) 1984. In the shelter of Elyon: essays on ancient Palestinian life in honour of GW Ahlström. JSOTSup 31. Sheffield: JSOT Press. Becker U, 2006. Endredaktionelle Kontextvernetzungen des Josua-Buches, in Witte, Schmid, Prechel and Gertz 2006:139–161. Bieberstein, K 1995. Josua-Jordan-Jericho. Archäologie, Geschichte und Theologie der Landnahmeerzählungen Josua 1–6. OBO. Friborg: Universitätsverlag, Göttingen: Vandenhoeck &amp; Ruprecht. Blum, E 1990. Studien zur Komposition des Pentateuch. BZAW 189. Berlin/New York: de Gruyter. _______ 1997. Die Kompositionelle Knoten am Übergang von Josua zu Richter: Ein Entflechtungsvorschlag, in Lust and Vervenne 1997:181–212. _______ 2006. The literary connection between the books of Genesis and Exodus and the end of the book of Joshua, in Dozeman and Schmid 2006:80–106. _______ 2011. Pentateuch-Hexateuch-Enneateuch, in Dozeman , Römer and Schmid 2011:43–71. Carr, D M 1996. Reading the fractures of Genesis. Historical and literary approaches. Louisville: Westminster John Knox. _______ 2006. What is required to identify pre-Priestly narrative connections between Genesis and Exodus? in Dozeman and Schmid 2006:159–180. _______ 2012. The Moses story: literary and historical reflections, HeBAI 1–2:7–36. Dozeman, T B &amp; Schmid, K (eds) 2006. Farewell to the Yahwist? The composition of the Pentateuch in recent European discussion. SBL Symposium Series 34. Atlanta: SBL. Dozeman, T B, Römer, T C &amp; Schmid, K (eds) 2011. Pentateuch, Hexateuch, or Enneateuch. Identifying literary works in Genesis through Kings. SBL 8. Atlanta: SBL. Du Pury, A, Römer, T C &amp; Macchi, J P (eds) 2000. Israel constructs its history. Deuteronomistic historiography in recent research. Sheffield: Sheffield Academic Press. Edenburg, C &amp; Pakkala, J (eds) 2013. Is Samuel amongst the Deuteronomists? Current views on the place of Samuel in a Deuteronomistic History. Atlanta: SBL. Eisffeldt, O 1964. Einleitung in das Alte Testament. Tübingen: Mohr. Frevel, C 2000. Mit Blick auf das Land die Schöpfung erinnern. Zum Ende der Priestergrundschrift. HBS 23. Freiburg/New York: Herder. _______ 2011. Die Wiederkehr der Hexateuchperspektive. Eine Herausforderung für die These vom Deuteronomistischen Geschictswerk, in Stipp 2011:13–53. Frey, J, Schattner-Rieser, U &amp; Schmid, K (eds) 2012. Die Sameritaner und die Bibel: Historische und literarische Wechselwirkungen zwischen biblischen und Sameritanischen Traditionen. Studia Judaica/Studia Samaritana 7. Berlin/New York. Fritz, V 1994. Das Buch Josua. Hat 1/7. Tübingen: Mohr Siebeck. Garciá-Martinez, F (ed.) 1998. Perspectives in the study of the Old Testament and early Judaism: a symposium in honour of Adam S. van der Woude on the occasion of his 70th Birthday. VTSup 73. Leiden: Brill. Gertz, J C 2000. Tradition und Redaktion in der Exoduserzählung. Untersuchungen zur Endredaktion des Pentateuch. FRLANT 186. Göttingen: Vandenhoeck&amp; Ruprecht. Görg, M 1991. Josua. NEB 26. Würzburg: Echter Verlag. Gunkel, H 1910. Genesis. 3rd ed. GHK 1. Göttingen: Vandenhoeck &amp; Ruprecht. Hjelm, I 2000. The Samaritans and early Judaism: a literary analysis. JSOTSup 303. Sheffield: Sheffield Academic Press. Keel, O 1973. Das Vergaben der “Fremder” Götter in Genesis xxxv 4b, VT 23:305–336. Knauf, E A 2000. Does Deuteronomsitic Historiography (DH) exist? in du Pury , Römer and Macchi 2000:388–398. _______ 2007. Buchschlüsse im Josuabuch, in Römer and Schmid 2007:217–224. _______ 2008. Josua. ZBKAT 6. Zurich: Theologisher Verlag. Knoppers, G N &amp; McConville, J G (eds) 2000. Reconsidering Israel and Judah: recent studies on the Deuteronomistic History. SBTS 8. Winona Lake: Eisenbrauns. Köckert, M 1988. Vätergott und Väterverheisssungen. Eine Auseinandersetzung mit Albrecht Alt und seine Erben. FRLANT 142. Göttingen: Vandenhoeck &amp; Ruprecht. Konkel, M 2008. Sünde und Vergebung:Eine Rekontruktion der Redaktionsgeschichte der hinterein Sinaiperikope (Ex 32–34). Vor dem Hintergrund aktueller Pentateuchmodelle. FAT 88. Tübingen: Mohr. Koopmans, W T 1990. Joshua 24 as poetic narrative. JSOTSup 93. Sheffield: JSOT Press. Kratz, R G 2000. Die Komposition der erzählender Bücher des Alten Testaments: Grundwissen der Bibelkritik. UTB 215.Göttingen: Vandenhoeck &amp; Ruprecht. Levin, C 1993. Der Jahwist. FRLANT 157.Göttingen: Vandenhoeck&amp; Ruprecht. Lipschits, O, Knoppers, G N &amp; Albertz, R (eds) 2007. Judah and the Judeans in the fourth century B.C.E. Winona Lake: Eisenbrauns. Lust, J &amp; Vervenne, M (eds) 1997. Deuteronomy and Deuteronomistic literature. BETL 133. Leuven: Peeters. Mckenzie, S L &amp; Römer, T C (eds) 2000. Rethinking the foundations: historiography in the ancient world and the Bible. Essays in honour of John Van Seters. Berlin/New York: de Gruyter. Nelson, R D 1997. Joshua: a commentary. Louisville: Westminster John Knox. Nentel, J 2000. Trägerschaft und Intentionen des deuteronomistischen Geschichtswerks: Untersuchungen zu Refelexionreden: Jos1; 23; 24; 1 Sam12 und 1 Kön 8. BZAW 297. Berlin: de Gruyter. Nihan, C 2012. The literary relationship between Deuteronomy and Joshua: a reassessment, in Schmid and Person 2012:79–114. _______ 2013. 1 Sam 8 and 12 and the Deuteronomsitic edition of Samuel, in Edenburg and Pakkala 2013: 225–274. Na`man, N 2000. The law of the altar in Deuteronomy and the cultic site near Shechem, in Mckenzie and Römer 2000:141–161. Noll, K L and Schramm, B (eds) 2010. Raising a faithful exegete: essays in honour of Richard Nelson. Winona Lake: Eisenbrauns. Noort, E 1997. The traditions of Ebal and Gerizim: theological positions in the book of Joshua, in Vervenne and Lust 1997:161–180. _______ 1998. Zu Stand und Perspektiven: Der Glaube Israels zwischen Religionsgeschichte und Theologie, der Fall Josua 24, in Garciá-Martinez 1998:82–108. Noth, M 1943. Überlieferungsgeschichtliche Studien. Tübingen: Niemeyer. _______ 1953. Das Buch Josua. 2nd ed. HAT 7. Tübingen: Mohr Siebeck. O’Brien, M A 1989. The Deuteronomistic History hypothesis: a reassessment. OBO 92. Fribourg: Éditions. Universitaires/Göttingen: Vandenhoeck&amp; Ruprecht. Otto, E 1999. Bruckensläge in der Pentateuchsforschung, TRU 64:84–99. _______ 2000. Das Deuteronomium im Pentateuch und Hexateuch. Studien zur Literaturgeschichte von Pentateuch und Hexateuch im Lichte des Deuteronomiumrahmens. FAT 30. Tübingen: Mohr Siebeck. Otto, E &amp; Achenbach, R (eds) 2004. Das Deuteronomium zwischen Pentateuch undDeuteronomistischem Geschictswerk. FRLANT 206. Göttingen: Vandenhoeck &amp; Ruprecht. Perlitt, L 1968. Bundestheologie im Altes Testament. Neukirchen-Vluyn: Neukirchener Verlag. _______ 1994. Priesterschrift in Deuteronomium34? VT 59:475–494. Popovich, M 2009. Conquest of the land, loss of the land. Where does Joshua 24 belong?, in von Ruiten and de Vos 2009:87–98. Rofé, A 2000. Ephraimite versus Deuteronomistic History, in Knoppers &amp; McConville 2000:462–474. Römer, T C 2010. Book-endings in Joshua and the question of the so-called Deuteronomistic History, in Noll and Schramm 2010:85–99. Römer, T C &amp; Brettler, M Z 2000. Deuteronomy 34 and the case for a Persian Hexateuch, JBL 119/3:401–419. Römer, T C and Schmid, K (eds) 2007. Les dernières rédactions du Pentatueque, de l` Hexateuge,et de l` Henneatuege. BETL 203. Leuven: Peeters. Rösel, H N 1980. Die Überleitungen vom Josua-ins Richterbuch, VT 30:342–350. Schmid K, 1999. Erzväter und Exodus: Untersuchungen zur doppelten Begründing der Ursprünge Israels innerhalb der Geschichtsbücher des Alten Testaments. WMANT 81. Neukirchen-Vluyn: Neukirchener Verlag. _______ 2007. The late Persian formation of the Torah: observations on Deuteronomy 34, in Lipschits, Knoppers &amp; Albertz 2007:236–245. _______ 2012. Die Sameritaner und die Judaër. Die biblische Diskussion um ihr Verhältnis in Josua 24, in Frey, Schattner-Rieser &amp; Schmid 2012:21–49. Schmid, K &amp; Person, R (eds) 2012. Deuteronomy in the Pentateuch, Hexateuch, and the Deuteronomistic History. Tübingen: Mohr Siebeck. Schmidt, L 2009. P in Deuteronomium 34, VT 59:475–494. Schmitt, G 1964. Der Landtag von Sichem. Stuttgart: Calwer Verlag. Schmitt, H C 2004. DTN 34 als Verbindingstuck zwischen Tetrateuch und Dtr. Geschictswerk, in Otto and Achenbach 2004:181–192. Smend, R 1970. Das Gesetz un die Völker, in Wolff 1970:494–504. Sperling, S D 1987. Joshua 24 re-examined. HUCA 58:119–136. Steuernage, l C 1923. Das Buch Josua. GHK 1,3 (2). Göttingen: Vandenhoeck &amp; Ruprecht. Stipp, H J (ed.) 2011. Das deuteronomistische Geschichtswerk. ÖBS 39. Frankfurt am Main: Peter Lang. Van Seters, J 1984. Joshua 24 and the problem of tradition in the Old Testament, in Barrick and Spencer 1984:139–158. _______ 2003. Deuteronomy between Pentateuch and Deuteronomistic History, HTS 59/3:947–956. Vervenne, M &amp; Lust, J (eds) 1997. Deuteronomy and Deuteronomistic literature. FS C.H.W Brekelmans. BETL 133. Leuven: Peeters. Von Ruiten, J and de Vos, C (eds) 2009. The land of Israel in Bible, history and theology: studies in honour of Ed Noort. VTSup 124. Leiden: Brill. Weimar, P 2008. Studien zur Priesterschrift. FAT 56. Tübingen: Mohr Siebeck. Westermann, C 1994. Die Geschictsbücher des Alten Testaments: Gab es ein deuteronomsitisches Geschichtswerk? TB Altes Testament 87. Gütersloh: Gütersloher Verlag. Witte, M 1998. Die biblische urgeschichte. Redaktions-und Theologiegeschichtliche Beobachtungen zu Genesis 1,1–11:26. BZAW 265. Berlin: de Gruyter. Witte M, Schmid K, Prechel, D &amp; Gertz, J C (eds) 2006. Die deuteronomistischenGeschichtswerke: Redaktions- und religionsgeschichtliche Perspektiven zur “Deuteronomismus”-Diskussion in Tora und vorderen Propheten. BZAW 365. Berlin: de Gruyter. Wolff, H W (ed.) 1970. Probleme biblischer Theologie: Gerard von Rad zum 70. Geburtstag. Munich: Kaiser Verlag. Würthwein, E 1994a. Erwägungen zum sog. Deuteronomistischen Geschichtswerk: eine Skizze, in Würthwein 1994b:1–11. Würthwein, E 1994b. Studien zum deuteronomistischen Geschichtswerk BZAW227. Berlin: de Gruyter, Zakovitch, Y 1980. The object of the narrative of the burial of the foreign gods at Shechem, BeTM 25:300–337. Zenger, E 2004. Einleitung in das Alte Testament. 5th ed. Stuttgart: Kohlhammer.
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Zhao, Li-Sha, Yan-Hua Cai, and Hui-Li Liu. "N, N’-sebacic bis(hydrocinnamic acid) dihydrazide: A crystallization accelerator for poly(L-lactic acid)." e-Polymers 19, no. 1 (2019): 141–53. http://dx.doi.org/10.1515/epoly-2019-0016.

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AbstractDeveloping more organic nucleating agent with different molecular structure is very instructive to improve the crystallization of poly(L-lactic acid) (PLLA) and explore the crystallization mechanism. In this study, N, N’-sebacic bis(hydrocinnamic acid) dihydrazide (HAD) was synthesized to serve as a nucleating agent for PLLA. The effects of HAD on the non-isothermal crystallization, melting behavior, thermal stability and optical performance of PLLA were investigated by differential scanning calorimeter (DSC), thermogravimetric analysis (TGA), and light transmittance meter. The melt crystallization behavior showed that HAD was able to promote the crystallization of PLLA via heterogenous nucleation in cooling, and it was found that, upon the cooling of 1°C/min, the incorporation of 1 wt% HAD made the crystallization temperature and non-isothermal crystallization enthalpy increase from 94.5°C and 0.1 J/g to 131.6°C and 48.5 J/g comparing with the pure PLLA. Additionally, the melt crystallization significantly depended on the cooling rate and the final melting temperature. For the cold crystallization, when the nucleation density from HAD and PLLA itself was saturated, the influence of the HAD concentration on the cold crystallization process of the PLLA/HAD samples is negligible. The melting behavior after isothermal or non-isothermal crystallization further confirmed the crystallization accelerating effect of HAD for PLLA, and the appearance of the double melting peaks was attributed to the melting-recrystallization. Unfortunately, the addition of HAD decreased the thermal stability and light transmittance of PLLA.
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Nguyen, Long Phi, Anh Phuoc Le, Theu Thi Luong, Huy Quang Tran, Nhan Thi Tran, and Bac Thi Viet Phung. "Computational fluid dynamics analysis of airflow patterns around rotating cylinders in the drafting system of a vortex spinning machine." EUREKA: Physics and Engineering, no. 6 (November 28, 2024): 81–92. http://dx.doi.org/10.21303/2461-4262.2024.003397.

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Akhtar, W. H., Watanabe, C., Tou, Y., Neittaanmäki, P. (2022). A New Perspective on the Textile and Apparel Industry in the Digital Transformation Era. Textiles, 2 (4), 633–656. https://doi.org/10.3390/textiles2040037 Bertola, P., Teunissen, J. (2018). Fashion 4.0. Innovating fashion industry through digital transformation. Research Journal of Textile and Apparel, 22 (4), 352–369. https://doi.org/10.1108/rjta-03-2018-0023 Erdumlu, N., Ozipek, B., Oxenham, W. (2012). Vortex spinning technology. Textile Progress, 44 (3-4), 141–174. https://doi.org/10.1080/00405167.2012.739345 VORTEX Spinning Machine. Murata Machinery. Available at: https://www.muratec.net/tm/products/vortex_spinning_machine.html Patel, P. C., Vasavada, D. A., Mankodi, H. R. (2012). Applications of electrically conductive yarns in technical textiles. 2012 IEEE International Conference on Power System Technology (POWERCON), 1–6. https://doi.org/10.1109/powercon.2012.6401374 Bhatti, M. R. A., Tausif, M., Mir, M. A., Umar, M., Cassidy, T. (2018). Effect of key process variables on mechanical properties of blended vortex spun yarns. The Journal of The Textile Institute, 110 (6), 932–940. https://doi.org/10.1080/00405000.2018.1532784 Pei, Z., Chen, G., Liu, C., Zhou, Q., Yu, C., Yang, J. et al. (2012). Experimental Study on the Fiber Motion in the Nozzle of Vortex Spinning via High-Speed Photography. Journal of Natural Fibers, 9 (2), 117–135. https://doi.org/10.1080/15440478.2012.683660 Zheng, S., Zou, Z., Shen, W., Cheng, L. (2012). A study of the fiber distribution in yarn cross section for vortex-spun yarn. Textile Research Journal, 82 (15), 1579–1586. https://doi.org/10.1177/0040517511431315 Zou, Z., Cheng, L., Xi, B., Luo, Y., Liu, Y. (2014). Investigation of fiber trajectory affected by some parameter variables in vortex spun yarn. Textile Research Journal, 85 (2), 180–187. https://doi.org/10.1177/0040517513509873 Shang, S., Sun, N., Yu, C., Chang, T., Li, M. (2014). Optimization of nozzle structure parameters of vortex spinning. Textile Research Journal, 85 (9), 998–1006. https://doi.org/10.1177/0040517514557308 Pei, Z., Yu, C. (2011). Numerical study on the effect of nozzle pressure and yarn delivery speed on the fiber motion in the nozzle of Murata vortex spinning. Journal of Fluids and Structures, 27 (1), 121–133. https://doi.org/10.1016/j.jfluidstructs.2010.08.007 Uyanık, S., Duru Baykal, P. (2017). Effects of fiber types and blend ratios on Murata Vortex yarn properties. The Journal of The Textile Institute, 109 (8), 1099–1109. https://doi.org/10.1080/00405000.2017.1408245 Senthilkumar, P., Kuthalam, E. S. (2015). Optimization of Spinning Parameters Influencing the Tensile Properties of Polyester/Cotton Vortex Yarn. Indian Journal of Fibre &amp; Textile Research (IJFTR), 40 (3), 256–266. Available at: https://nopr.niscpr.res.in/bitstream/123456789/32194/1/IJFTR%2040%283%29%20256-266.pdf Yali, V., Akdoğanözü, R., Kalayci, Y. E., Göktepe, F. (2020). An Investigation of the Effect of Delivery Speed and Nozzle Air Pressure on Viscose. Tekstil ve Mühendis, 27 (117), 2–11. https://doi.org/10.7216/1300759920202711701 ANSYS Fluent. Available at: https://www.ansys.com/products/fluids/ansys-fluent ANSYS FLUENT 12.0 User's Guide. Available at: https://www.afs.enea.it/project/neptunius/docs/fluent/html/ug/main_pre.htm Aeronautics and Astronautics (1959). Proc. of Durand Centennial Conf.
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SUASSUNA, Lívia, and Sabrina Leite FELIX. "SABERES EM MOVIMENTO NO ESTÁGIO DE REGÊNCIA DE TURMA: O ENSINO DE ANÁLISE LINGUÍSTICA POR GRADUANDOS DE LETRAS." Trama 17, no. 41 (2021): 09–27. http://dx.doi.org/10.48075/rt.v17i41.26732.

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Neste estudo pretendemos analisar o modo como alunos da licenciatura em Letras-Português da Universidade Federal de Pernambuco, durante o estágio curricular, atuam para ensinar seus alunos a refletir sobre a língua, concretizando um dos eixos de ensino desse componente curricular que é a análise linguística. A pesquisa, do tipo qualitativo-descritiva, teve como corpus projetos e relatórios de estágio, além de depoimentos dos estagiários, captados no seminário de encerramento das atividades de regência de turma do ensino fundamental. Para montar o referencial teórico, buscamos autores que tratam da formação docente, do estágio e do ensino de análise linguística. Os resultados mostraram que os futuros professores trabalham numa perspectiva sociointeracionista e exploram uma diversidade de gêneros textuais, como indicado nas orientações mais recentes para o ensino de língua portuguesa. No entanto, a maioria deles explicita pouco os procedimentos didáticos realizados, não indica as dificuldades dos alunos quando da avaliação da aprendizagem e aborda determinados conhecimentos linguísticos de forma expositiva e dedutiva.Referências:ALMEIDA FILHO, J. C. Crise, transições e mudança no currículo de formação de professores de línguas. In: FORTKAMP, M. B. M.; TOMITCH, L. M.B. (org.). Aspectos da linguística aplicada: estudos em homenagem ao professor Hilário Inácio Bohn. Florianópolis: Insular, 2000. p. 33-47.AZEVEDO, T. M. Ensinar gêneros? Desenredo, Passo Fundo, RS, v. 10, n. 1, p. 92-103 - jan./jun. 2014.AZEVEDO, T. M. Transposição didática de gêneros discursivos: algumas reflexões. Desenredo. Passo Fundo, RS, v. 6, n. 2, p. 198-214 - jul./dez. 2010.BARBOSA, J. Análise e reflexão sobre a língua e as linguagens: ferramentas para os letramentos. In: RANGEL, E. O.; ROJO, R. H. R. (org.) Língua Portuguesa no Ensino Fundamental. Coleção Explorando o Ensino. vol. 19. Brasília: MEC/SEB, 2010, p. 155-182.CALLIAN, G. R.; BOTELHO, L. S. A análise linguística e o ensino de língua portuguesa: em busca do desenvolvimento da competência discursiva. Educação em Destaque. Juiz de Fora, MG, v. 5, n. 1, p. 1-21, 2014.DICKEL, A. Ensino de gramática: das polêmicas às proposições. In: SEMINÁRIO NACIONAL SOBRE LINGUAGENS E ENSINO, 7, 2012, Pelotas. Anais... Pelotas: UCPel, 2012.DUTRA. C. M. D.; LOULA, L. D. Incompreensão e desalinhamento teórico-metodológico como possíveis entraves à prática de análise linguística em sala de aula. Domínios de Lingu@gem, Uberlândia, MG, vol. 11, n. 3, p. 526-547, jul./set. 2017.EMILIO, A. Gramática, deve-se ou não se deve ensinar? Línguas Letras. Cascavel, PR, v. 9. n. 16, p. 27-35. 2007.GERALDI, J. W. Concepções de linguagem e ensino de português. In: GERALDI, J. W. (org.). O texto na sala de aula. São Paulo: Ática, 1997[1984], p. 39-46.GERALDI, J. W. Unidades básicas do ensino de português. In: GERALDI, J. W. (org.). O texto na sala de aula: leitura e produção. Cascavel: Assoeste, 1984, p. 49-69.LARROSA, Jorge. Algunas notas sobre la experiencia y sus lenguajes. In: BARBOSA, R. L. L. (org.). Trajetórias e perspectivas da formação de educadores. São Paulo: Ed. Unesp, 2004. p.19-34.LOMBARDI, R. F. e ARBOLEA, T. A. Formando professores pesquisadores do ensino de língua materna. In: CONGRESSO LATINO-AMERICANO SOBRE FORMAÇÃO DE PROFESSORES DE LÍNGUA. 1, Florianópolis, Anais... 2006, p. 614-619.MENDONÇA, M. Análise linguística: por que e como avaliar. In: Marcuschi, B. SUASSUNA, L. (org.). Avaliação em língua portuguesa: contribuições para a prática pedagógica. Belo Horizonte: Autêntica, 2007, p. 95-110.NÓBREGA, J. J.; SUASSUNA, L. Aula de gramática ou de análise linguística? Investigando objetos de estudo e objetivos norteadores. Linguagens, Educação e Sociedade. Teresina, PI, n. 31, p. 246-269, jul. 2014.OLIVEIRA, M. B. F. Revisitando a formação de professores de língua materna: teoria, prática e construção de identidades. Linguagem em (Dis)curso. Tubarão, SC, v. 6, n. 1, p. 101-117, jan./abr. 2006.PETRONI, M. R.; JUSTINO, A. R.; MELO, E. S. O. Ainda sobre a formação do professor de língua portuguesa no Brasil. Interacções, Santarém, PT, n. 19, p. 28-37, 2011.PIMENTA, S. G.; LIMA, M. S. L. Estágio e docência: diferentes concepções. Poiésis. Tubarão, SC, vol. 3, números 3 e 4, p. 5-24, 2006.RAUBER, A. L. A formação do professor de Língua Portuguesa: o diálogo entre teoria e prática. In: MAGALHÃES, J. S.; TRAVAGLIA, L. C. (org.). Múltiplas perspectivas em linguística. Uberlândia/MG: EDUFU, 2008, v. 01, p. 346-356.REINALDO, M. A. G. M. O conceito de análise linguística como eixo de ensino de língua portuguesa no Brasil. Estudos Linguísticos, n. 8. Edições Colibri/CLUNL, Lisboa, p. 229-241, 2012.REMENCHE, M. L. R.; ROHLING, N. Análise linguística e formação de professores: um discurso sobre a dicotomia teoria e prática. In: SIMPÓSIO MUNDIAL DE ESTUDOS DE LÍNGUA PORTUGUESA. SIMELP. 5, 2017. Salento. Atas... Salento: Università del Salento, 2017.SILVA, N. I. Ensino tradicional de gramática ou prática de análise linguística: uma questão de (con)tradição nas aulas de português. Revista Brasileira de Linguística Aplicada. Belo Horizonte, MG, v. 10, n. 4, p. 949-973, 2010.SILVA, W. R.; FAJARDO-TURBIN, A. E. F. Relatório de estágio supervisionado como registro da reflexão pela escrita na profissionalização do professor. Polifonia, Cuiabá, MT, v. 18, n. 23, p. 103-128, jan./jun., 2011.SIQUEIRA, R. A. R.; MESSIAS, R. A. L. Reflexão e ações na formação e atuação do professor de língua portuguesa: o diálogo como condição de autoria na prática educativa. In: Linguagem Ensino, Pelotas, RS, v.11, n.2, p.377-392, jul./dez. 2008.SUASSUNA, L. Ensino de análise linguística: situando a discussão. In: SILVA, A.; PESSOA, A. C.; LIMA, A. (org.). Ensino de gramática: reflexões sobre a língua portuguesa na escola. Belo Horizonte, MG: Autêntica Editora, 2012, p. 11-28.TARDIF, M.; LESSARD, C.; LAHAYE, L. Os professores face ao saber: esboço de uma problemática do saber docente. Teoria e Educação, Porto Alegre, RS, v. 04, p. 215-233, 1991.VIEIRA, S. R. Prática de análise linguística sem ensino de gramática? Reflexões e propostas. In: ATAÍDE, C. et al. (org.). GELNE 40 anos. Experiências teóricas e práticas nas pesquisas em Linguística e Literatura. Paulo: Blucher, 2017, p. 299-318. Recebido em 05-01-2021Revisões requeridas em 28-04-2021Aceito em 12-05-2021
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47

Mashak, Zohreh, Ali Zabihi, Hamidreza Sodagari, Negin Noori, and Afshin Akhondzadeh Basti. "Prevalence of Listeria monocytogenes in different kinds of meat in Tehran province, Iran." British Food Journal 117, no. 1 (2015): 109–16. http://dx.doi.org/10.1108/bfj-09-2013-0268.

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Purpose – The purpose of this paper is to determine the prevalence of Listeria monocytogenes as an important foodborne pathogen in different kinds of meat. Design/methodology/approach – In total, 410 samples, including fresh and frozen meats of turkey, quail, chicken, ostrich, cattle, sheep and camel, fresh chicken liver and fresh minced meat were gathered and then analyzed according to USDA-FSIS method. To enumerate L. monocytogenes, the MPN procedure was used and also, strains were serotyped by using commercial specific antisera. Findings – It was found that 28.05 percent of samples were positive for L. monocytogenes and the contamination of beef meat was higher than the others. The range of microbial load was from &lt;2 to 940 MPN g−1. Most of the samples (94.39 percent) had a microbial load of &lt;100 MPN g−1. Moreover, 56 percent of the strains belonged to serogroup 1, especially to 1/2a, although, the most frequently isolated serotype was serotype 4b (38.3 percent) in all samples. These findings indicate the potential risk of contamination in different kinds of meats by L. monocytogenes. Originality/value – This survey is of academic value and of value to those working in the food hygiene and safety. Also, to the best knowledge of these researchers, there has been no serious research on this topic with all its aspects in Iran.
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48

Uloza, Virgilijus, Toma Tamauskaite, Alvita Vilkeviciute, Agne Pasvenskaite, Vykintas Liutkevicius, and Rasa Liutkeviciene. "Determination of SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, and RAGE rs1800625 Single Gene Polymorphisms in Patients with Laryngeal Squamous Cell Carcinoma." Disease Markers 2019 (November 12, 2019): 1–9. http://dx.doi.org/10.1155/2019/3907232.

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Purpose. To determine the frequency of the genotype of signal transducer and activator of transcription protein 3 (STAT3) rs744166, sirtuin (SIRT1) rs12778366, fibroblast growth factor (FGFR2) rs2981582, and advanced glycosylation end product-specific receptor (RAGE) rs1800625 gene polymorphisms in patients with laryngeal squamous cell carcinoma (LSCC). Methods. A total of 944 subjects were evaluated, which includes 144 patients with LSCC and 800 healthy controls. The genotyping of STAT3 rs744166, SIRT1 rs12778366, FGFR2 rs2981582, and RAGE rs1800625 was carried out using the RT-PCR. Results. The analysis of STAT3 rs744166, SIRT1 rs12778366, and FGFR2 rs2981582 gene polymorphisms did not reveal any differences in genotype distribution between the patients with LSCC and the control subjects. However, statistical analysis revealed that genotypes (AA, AG, and GG) of rs1800625 in RAGE gene were distributed statistically significantly differently between patients and controls (61.1%, 30.6%, and 23.6% vs. 72.5%, 25.8%, and 1.8%, respectively; p&lt;0.001). Additionally, statistical significance was observed in allele distribution between these two groups, i.e., allele G at rs1800625 was more frequently observed in the patient group than in controls (23.6% vs. 14.6%; p&lt;0.001). Conclusion. RAGE rs1800625 gene polymorphism may play a significant role in laryngeal squamous cell carcinoma development.
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49

Amin, Roshdi Soliman, Mahmoud Ahmed Rabab, Abdalla Ahmed, and Soliman Mahmoud. "Study of combination of ascorbic acid and N-acetylcysteine in prevention of contrast induced nephropathy in patients with moderate renal insufficiency." Biolife 5, no. 4 (2022): 527–34. https://doi.org/10.5281/zenodo.7393076.

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<strong>ABSTRACT</strong> Introduction and aims: Despite fluid administration is the most effective strategy in contrast induced nephropathy (CIN) prevention, still the estimated prevalence of CIN up to 50% in high-risk patients. There is still a great debate as regarding the administration of antioxidants in reduction of CIN incidence. This study aims to determine whether addition of ascorbic acid to IV acetylcysteine could reduce CIN prevalence in patients with moderate chronic kidney disease. Methods: We conducted prospective, randomized, double blind, placebo-controlled trial on 106 patients scheduled for elective coronary or aorto-iliac angiography. The patients were divided in two groups: Group 1 (n = 53) receive hydration and placebo while Group 2 (n = 53), received IV 1200mg acetylcysteine , 2g ascorbic acid and hydration before and after the procedure. Occurrence of more than a 25% increase in serum creatinine level within 5 days after contrast administration considered as CIN. Results: The incidence of CIN was significantly lower in Group 2 (3.7%) compared with Group 1 (12%) p=0.02. A lower average serum creatinine (P= 0.01) and a higher average creatinine clearance was found in Group 2 after 5 days of contrast administration (P= 0.01). Patients receiving placebo had a longer hospital stay than patients receiving a combination of NAC and ascorbic acid (p&lt;0.02). Conclusion: In our study, prophylactic oral administration of the antioxidant ascorbic acid in addition to high dose IV N-acetylcysteine diminish the incidence of CIN in patients with moderate CKD with minimal adverse effects and at a low cost. <strong>Key words:&nbsp; </strong>Ascorbic acid; N-Acetylcysteine; Contrast Nephropathy; Moderate CKD. <strong>REFERENCES</strong> Goldenberg I, Matetzky S. Nephropathy induced by contrast media: Pathogenesis, risk factors &amp; preventive strategies. CMAJ. 2005;172:1461&ndash;71. Bartels ED, Brun GV, Gammeltoft A, Gjorup PA. Acute anuria following intravenous pyelography in a patient with myelomatosis. Acta Med Scand. 1954;150:297&ndash;302.&nbsp; Hossein Nough,&nbsp; a Fatemeh Eghbal, a Mohammad hossein Soltani, a Farzaneh Nejafi, a Hossein Falahzadeh, a Habib Fazel, and Mehrdad Sheikhvatanb. Incidence and Main Determinants of Contrast-Induced Nephropathy following Coronary Angiography or Subsequent Balloon Angioplasty. Cardiorenal Med. 2013 Jul; 3(2): 128&ndash;135. Mohammed Habib, Alaa Hillis, Amen Hammad. N-Acetylcysteine and/or Ascorbic Acid versus Placebo to Prevent Contrast-Induced Nephropathy in Patients Undergoing Elective Cardiac Catheterization: The NAPCIN Trial; A Single-Center, Prospective, Randomized Trial Mohammed Saudi J Kidney Dis Transpl 2016; 27(1):55-61. Wattanakit K, Folsom AR, Selvin E, et al. Kidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) Study. J Am Soc Nephrol 2007; 18:629. De Lima JJG, Sabbaga E, Vieira MLC, et al. Coronary angiography is the best predictor of events in renal transplant candidates compared with noninvasive testing. Hypertension. 2003; 42:263&ndash;8. Gonzales DA, Norsworthy KJ, Kern SJ, et al. A meta-analysis of n-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity. BMC Med 2007; 5:32. Kelly AM, Dwamena B, Cronin P, et al. Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy. Ann Intern Med 2008; 148:284&ndash;94. Biondi-Zoccai GG, Lotrionte M, Abbate A, et al. Compliance with quorum and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study. BMJ 2006; 332:202&ndash;9. Spargias K, Alexopoulos E, Kyrzopoulos S, et al. Ascorbic acid prevents contrast-mediated nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. Circulation 2004; 110:2837&ndash;42. Roger Rear, Robert M Bell, Derek J Hausenloy. Contrast-induced nephropathy following angiography and cardiac interventions. BMJ 2016; 0:1&ndash;11. Windecker S, Kolh P, Alfonso F, et al., Authors/Task Force members. 2014 ESC/EACTS guidelines on myocardial revascularization: the task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J 2014; 35:2541&ndash;619. Mark D. Okusa and Andrew Davenport . Reading between the (guide) lines&mdash;the KDIGO practice guideline on acute kidney injury in the individual patient. Kidney Int. 2014 Jan; 85(1): 10.1038/ki.2013.378. Finn WF. The clinical and renal consequences of contrast-induced nephropathy. Nephrol Dial Transplant. 2006 Jun. 21(6):i2-10). Kelly AM, Dwamena B, Cronin P, et al. Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy. Ann Intern Med 2008;148:284&ndash;94. Fliser D, Laville M, Covic A, et al , ERBP A-HWG. A European renal best practice (ERBP) position statement on the kidney disease improving global outcomes (KDIGO) clinical practice guidelines on acute kidney injury: part 1: definitions, conservative management and contrast-induced nephropathy. Nephrol Dial Transpl 2012;27:4263&ndash;72. Renfan Xu, Anyu Tao, Yang Bai, Youbin Deng, Guangzhi Chen. Effectiveness of N‐Acetylcysteine for the Prevention of Contrast‐Induced Nephropathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials. Journal of the American Heart Association. 2016;5:e003968 Swapna Gurrapu and Estari Mamidala<strong>.</strong> Medicinal Plants Used By Traditional Medicine Practitioners in the Management of HIV/AIDS-Related Diseases in Tribal Areas of Adilabad District, Telangana Region. The Ame J Sci &amp; Med Res.2016:2(1):239-245. doi:10.17812/ajsmr2101 Umar Sadat, Ammara Usman,&nbsp; Jonathan H. Gillard , Jonathan R. Boyle . Does Ascorbic Acid Protect Against Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Systematic Review With Meta-Analysis of Randomized, Controlled Trials. Journal of the American College of Cardiology. 2013; 2167-2175. Hojat Naghavi, and Shahram Amini. Efficacy of Ascorbic Acid on Reducing the Development of Contrast-Induced Nephropathy. Razavi Int J Med. In press (In press):e37341. Published online 2016 November 19. Doi: 10.5812/rijm.37341. Pruijm M, Hofmann L, Vogt B, et al. Renal tissue oxygenation in essential hypertension and chronic kidney disease. Int J Hypertens 2013; 2013:696598. doi: 10.1155/2013/696598. Kolh P, Wijns W, Danchin N, et al. Guidelines on myocardial revascularization. Eur J Cardiothorac Surg 2010; 38 (Suppl): S1&ndash;S52. U. C. Brewster and M. A. Perazella, &ldquo;The renin-angiotensin-aldosterone system and the kidney: effects on kidney disease,&rdquo; The American Journal of Medicine 2004, vol. 116, no. 4, pp. 263&ndash;272. Fleming, K. Kohlstedt, and R. Busse, &ldquo;New FACEs to the renin-angiotensin system,&rdquo; Physiology, 2005. vol. 20, no. 2, pp. 91&ndash;95. G. Dangas, I, Iakovou, E, Nikolsky et al., &ldquo;Contrast-induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables,&rdquo; The American Journal of Cardiology, 2005.vol. 95, no. 1, pp. 13&ndash;19. J. L. Rosenstock, R. Bruno, J. K. Kim et al., &ldquo;The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy,&rdquo; International Urology and Nephrology, 2008. vol. 40, no. 3, pp. 749&ndash;755. C. Spatz, L. Saadulla, A. Lapsiwala, A. Parhizgar, and N. Ghahramani, &ldquo;Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease,&rdquo; Iranian Journal of Kidney Diseases,2012. vol. 6, no. 6, pp. 432&ndash;436. X. Li, T. Li, and H. Cong, &ldquo;Is angiotensin-converting enzyme inhibitor a contraindication for contrast-induced nephropathy prophylaxis? A review about its paradox,&rdquo; Cardiovascular Therapeutics, 2012.vol. 30, no. 5, pp. 273&ndash;276. Xiao-sheng Guo, Deng-xuan Wu, Wei-jie Bei1, Hua-long Li1, Kun Wang, Ying-ling Zhou1, et al. Intensity of hydration changes the role of renin&ndash;angiotensin&ndash;aldosterone system blockers in contrast-induced nephropathy risk after coronary catheterisation in patients with chronic kidney disease. Journal of the Renin-Angiotensin- Aldosterone System April-June 2017: 1&ndash;8 Bannwart C., Hagmaier V., Straumann E., Hofer H., Vuillemier J.P., Rutishauser G. Modification of urinary pH through ascorbic acid.&nbsp; Helv Chir Acta 1981; 48:425&ndash;428. Rajendra Gokhroo, Kamal Kishor, Bhanwar Ranwa A, Avinash Kumari, Priti Devendra, Bisht Sajal et al . N-acetyl cystein, ascorbic acid and intravenous hydration in reducing risk of contrast induced nephropathy: AJMER CIN study (Acetylcystein ascorbic acid to rejuvenate Medulla at high Risk for CIN): interim analysis. Quality in Primary Care (2015) 23 (2): 65-69. Monirah A Albabtain&nbsp; , Ali Almasood , Hytham Alshurafah , Hussain Alamri , Hani Tamim. Efficacy of Ascorbic Acid, N-Acetylcysteine, or Combination of Both on Top of Saline Hydration Versus Saline Hydration Alone on Prevention of Contrast-Induced Nephropathy: A Prospective Randomized Study. J Interv Cardiol 2012; 26 (1), 90-96. Carlo Briguori , Flavio Airoldi , Davide D&#39;Andrea , Erminio Bonizzoni , Nuccia Morici , Amelia Focaccio , et al. Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): A Randomized Comparison of 3 Preventive Strategies. Circulation 2007; 115 (10), 1211-1217.&nbsp; Lingaiah, Estari Mamidala and P. Nagaraja Rao (2015). An ethnobotanical survey of medicinal plants extracts used for the treatment of diabetes mellitus in the Utnoor Mandal of Adilabad dist, Telangana, India. Biolife. 3(4); 937-945. DOI: 10.17812/blj.2015.3429 Mahmoud Elsayed Abdelatif, Hazem Alakabawy, Mohamed Fawzy, Abdelraouf Fahmy (2017). Comparison between coronary artery bypass surgery and percutaneous coronary intervention with drugeluting stents for Egyptian diabetic patients with Multivessel disease. Biolife. 5(3), pp 295-302. doi:10.17812/blj.2017.5301
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50

Guinsburg, Ruth, Maria Fernanda Branco de Almeida, Junia Sampel de Castro, et al. "T-piece versus self-inflating bag ventilation in preterm neonates at birth." Archives of Disease in Childhood - Fetal and Neonatal Edition 103, no. 1 (2017): F49—F55. http://dx.doi.org/10.1136/archdischild-2016-312360.

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ObjectiveTo verify whether the use of the T-piece resuscitator compared with the self-inflating bag in preterm infants ventilated at birth modifies survival to hospital discharge without major morbidities.DesignPragmatic prospective cohort study.Setting20 Brazilian university hospitals of Brazilian Network on Neonatal Research. Patients were 1962 inborn infants in 2014–2015 ventilated at birth with 23–33’ weeks gestation and birth weight 400–1499 g without malformations. Patients transferred until the 27th day after birth were excluded.InterventionsPositive pressure ventilation at birth with T-piece resuscitator or self-inflating bag without positive end expiratory pressure valve. Intervention with ventilation followed the Brazilian Society of Pediatrics guidelines. The choice of the equipment was at the neonatologist’s discretion in each delivery. The main outcome measures were survival to hospital discharge without bronchopulmonary dysplasia, severe peri-intraventricular haemorrhage and periventricular leucomalacia. Logistic regression adjusted for confounding variables was applied for main outcome.Results1456 (74%) were only ventilated with T-piece resuscitator and 506 (26%) with the self-inflating bag. The characteristics of those ventilated with T-Piece resuscitator versus self-inflating bag were birth weight 969 ± 277 vs 941 ± 279 g, gestational age 28.2±2.5 vs 27.8±2.7 weeks and survival to hospital discharge without major morbidities 47% vs 35%. Logistic regression adjusted for maternal characteristics, obstetric and neonatal morbidities showed that the T-piece resuscitator increased the chance of survival to hospital discharge without major morbidities (OR=1.38; 95% CI 1.06 to 1.80; Hosmer-Lemeshow goodness of fit: 0.695).ConclusionThis study is the first that highlights the effectiveness of T-piece resuscitator ventilation in improving relevant outcomes in preterm neonates.
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