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Journal articles on the topic '21st regiment'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Ristic, Lidija, Milan Rancic, and Milan Radovic. "Tuberculosis in the 21st century: Challenges, endeavors and recommendations to doctors." Medical review 63, no. 11-12 (2010): 811–15. http://dx.doi.org/10.2298/mpns1012811r.

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The magnitude of problem with tuberculosis lies in the fact that one third of the world population is infected by Mycobacterium tuberculosis. Even in the 21st century, tuberculosis kills more people than any other infective agent. Definition of case of resistance - the case of resistant tuberculosis is precisely defined by the recommendations of the World Health Organization as primary, initial, acquired multidrug resistant and extensively drug resistant tuberculosis. The development of resistance tuberculosis may result from the administration of monotherapy or inadequate combinations of anti

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Goulka, Jeremiah E. "Memoirs of a Dutch Mudsill: The "War Memories" of John Henry Otto, Captain, Company D, 21st Regiment Wisconsin Volunteer Infantry (review)." Civil War History 52, no. 2 (2006): 209–10. http://dx.doi.org/10.1353/cwh.2006.0021.

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Taylor, David O. "Cardiac transplantation: drug regimens for the 21st century." Annals of Thoracic Surgery 75, no. 6 (2003): S72—S78. http://dx.doi.org/10.1016/s0003-4975(03)00482-x.

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Nowińska, Anna. "Current Opinion on Long-Lasting Therapy in CI-DME." Journal of Ocular Diseases and Therapeutics 10 (May 3, 2023): 1–10. http://dx.doi.org/10.12974/2309-6136.2023.10.01.

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Diabetes has been recognized by the World Health Organization (WHO) as a noncommunicable, chronic disease and a 21st century epidemic. Diabetic retinopathy (DR) is one of the three leading causes of blindness among the working-age population aged 20 to 74 years. Diabetic macular edema (DME) is the most common cause of vision loss in diabetic patients, and the impact of DME on quality of life is very significant. Currently, first-line treatment recommendations for center-involved DME (CI-DME) include intravitreal anti-VEGF injections on a monthly or bimonthly regimen. It is essential to u

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Ananthula, Aneesha, Katharine Thomas, Lily Chen, et al. "Abstract P4-07-21: Neo-adjuvant chemotherapy in various breast cancer subtypes in the 21st century." Cancer Research 83, no. 5_Supplement (2023): P4–07–21—P4–07–21. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-07-21.

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Abstract Introduction Breast cancer is a complex, heterogeneous disease encompassing a spectrum of subtypes with distinct biological features, each having unique responses to various treatment modalities and different clinical outcomes. The type of neoadjuvant chemotherapy (NAC) for locally advanced breast cancer is decided based on breast cancer subtype, which includes triple negative breast cancer (TNBC), hormone receptor positive breast cancer (HR+BC), HER2+ breast cancer (HER2+BC) and triple positive breast cancer (TPBC). Multiple NAC regimens exist but have not been directly compared to d

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Liu, A., L. Fanning, H. Chong, et al. "Desensitization regimens for drug allergy: state of the art in the 21st century." Clinical & Experimental Allergy 41, no. 12 (2011): 1679–89. http://dx.doi.org/10.1111/j.1365-2222.2011.03825.x.

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Fragodimitri, Christina, Vasiliki Schiza, Anastasios Giakoumis, et al. "Successful chelation in beta-thalassemia major in the 21st century." Medicine 102, no. 41 (2023): e35455. http://dx.doi.org/10.1097/md.0000000000035455.

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This century has seen a revolution the management of beta-thalassemia major. Over a 12-year period to 2016, we aimed to analyze the benefits of such advances. In 209 patients, independent of the chelation regimen, ferritin, cardiac T2* and liver iron concentration changes were evaluated. We defined chelation success (ChS) as no iron load in the heart and acceptable levels in the liver. Over 3 early magnetic resonance imagings, the same parameters were assessed in 2 subgroups, the only 2 that had sufficient patients continuing on 1 regimen and for a significant period of time, 1 on deferrioxami

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Gasparotto, Michela, Mariele Gatto, Valentina Binda, Andrea Doria, and Gabriella Moroni. "Lupus nephritis: clinical presentations and outcomes in the 21st century." Rheumatology 59, Supplement_5 (2020): v39—v51. http://dx.doi.org/10.1093/rheumatology/keaa381.

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Abstract Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the epidemiology of LN and its clinical presentation have been changing. However, even though retrospective cohort studies report a decreased mortality rate and an improvement in the disease prognosis, the percentage of patients progressing into end stage renal disease (ESRD) keeps steady despite the improvements in therapeutic strategies. Current in-use medications have been available for decades now, yet over the years, regimens for optimizing their efficacy and minimizing toxicity have been devel

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Rusakaniko, Chomunorwa. "Barriers to Democratic Governance: The Case of Movement for Democratic Change in Zimbabwe (1999-2013)." Greener Journal of Political and Social Sciences 1, no. 1 (2013): 9–27. https://doi.org/10.15580/gjpss.2013.1.032414157.

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The article is mainly concerned with the challenges facing Movement for Democratic Change in its quest for democratic governance in post colonial Zimbabwe in the 21st century. Among these challenges they include ideological, problems of political acceptance, rejection from continental institutions, political violence and security problems among others. Therefore, each challenge is analysed with the sole intention of exposing how this has become a challenge to MDC’s quest for power.

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Barrett, A. John, and Sawa Ito. "The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century." Blood 125, no. 21 (2015): 3230–35. http://dx.doi.org/10.1182/blood-2014-10-567784.

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Abstract The introduction of tyrosine kinase inhibitors (TKIs), a treatment of chronic myelogenous leukemia (CML), has largely replaced curative strategies based on allogeneic stem cell transplantation (SCT). Nevertheless, SCT still remains an option for accelerated/blastic-phase and selected chronic-phase CML. Transplant outcomes can be optimized by peritransplant TKIs, conditioning regimen, BCR-ABL monitoring, and relapse management. Controversies exist in transplant timing, pediatric CML, alternative donors, and economics. SCT continues to serve as a platform of “operational cure” for CML w

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Toleman, Mark A., Peter M. Bennett, and Timothy R. Walsh. "ISCR Elements: Novel Gene-Capturing Systems of the 21st Century?" Microbiology and Molecular Biology Reviews 70, no. 2 (2006): 296–316. http://dx.doi.org/10.1128/mmbr.00048-05.

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SUMMARY “Common regions” (CRs), such as Orf513, are being increasingly linked to mega-antibiotic-resistant regions. While their overall nucleotide sequences show little identity to other mobile elements, amino acid alignments indicate that they possess the key motifs of IS91-like elements, which have been linked to the mobility ent plasmids in pathogenic Escherichia coli. Further inspection reveals that they possess an IS91-like origin of replication and termination sites (terIS), and therefore CRs probably transpose via a rolling-circle replication mechanism. Accordingly, in this review we ha

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Meškova, Sandra. "SEMANTICS OF THE DEPICTION OF DAUGAVPILS IN ANITA LIEPA’S DOCUMENTARY PROSE AND FICTION." Via Latgalica, no. 6 (December 31, 2014): 64. http://dx.doi.org/10.17770/latg2014.6.1658.

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<p>Anita Liepa (born 1928) is a contemporary Latvian prose writer whose creative work was closely related to the post-soviet period in Latvia in the late 20th – and the beginning of the 21st century. In her works she depicted significant evidence of complex and contradictory processes in the history of Latvia in the 20th century, especially those related to World War II and its consequences for Latvia. Her works are divided into two distinct groups: documentary prose and fiction. The writer was born in Daugavpils, a town on the south-eastern border of Latvia, that had a significant role

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Pluzhnikova, T. A., E. A. Mikhnina, V. A. Kazantsev, and V. F. Bezhenar. "Miscarriage in patients with chronic endometritis and luteal phase deficiency. Principles of treatment and prevention." Voprosy ginekologii, akušerstva i perinatologii 20, no. 1 (2021): 55–63. http://dx.doi.org/10.20953/1726-1678-2021-1-55-63.

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Permanent inflammation of the endometrium against the background of altered vaginal microbiota is accompanied by a violation of cyclic tissue changes. The revealed deficiency of the secretory phase of the cycle was formed independently of the synthesis of progesterone by the corpus luteum and led to impaired embryo implantation and miscarriage. Objective. To evaluate the efficiency of dydrogesterone in miscarriage in patients with chronic endometritis (CE) with luteal phase deficiency. Patients and methods. The study involved 127 women aged 25 to 40 years non-pregnant and during pregnancy with

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Tolentino, Regina, and Virginia Margallo. "Rheumatic Heart Disease Management: Patients’ Experiences, Health Practices, and Role Performance." JPAIR Multidisciplinary Research 37, no. 1 (2019): 158–67. http://dx.doi.org/10.7719/jpair.v37i1.708.

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Rheumatic Heart Disease (RHD) continues to be a major health hazard in most developing countries as well as sporadically in developed economies. This study aimed to determine the drug regimen therapy of rheumatic heart disease patients and the effects of the illness physically, emotionally, and socially. This qualitative and quantitative study documented the drug regimen therapy management of twenty-seven (27) patients among the eighty-two (82) patients currently receiving the drug regimen for Rheumatic Heart Disease at the Out-Patient Department (OPD) of Cotabato Regional and Medical Center (

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Rogov, R. V., Zh Yu Muradyan, and I. G. Ryazanov. "Evaluation of the effectiveness of ironcontaining drugs in the complex therapy of antenatal hypotrophy of piglets." Veterinariya, Zootekhniya i Biotekhnologiya 1, no. 6 (2021): 13–17. http://dx.doi.org/10.36871/vet.zoo.bio.202106002.

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In the conditions of the pig breeding complex, the effectiveness of two treatment regimens for antenatal hypotrophy of piglets was studied. Two groups of piglets were formed, where the ironcontaining drug «Ursoferran – 200» was used in complex therapy in the 1st experimental group, and «Ferropen-200»in the 2nd experimental group. In a clinical study, hypotrophic piglets showed characteristic symptoms of the disease. In the experiment, the live weight of piglets was measured at the time of farrowing and on the 3rd, 7th, 14th and 21st days of life. The hematological parameters were studied. The

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Chernov, G. N. "Efficacy of subconjunctival injections of triamcinolone acetonide in the treatment of chronic recurrent episcleritis refractory to standard therapy." Modern technologies in ophtalmology, no. 2 (May 29, 2023): 181–85. http://dx.doi.org/10.25276/2312-4911-2023-2-181-185.

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Aim. To evaluate the safety and efficacy of the treatment of chronic recurrent episcleritis, not amenable to the standard treatment regimen, by subconjunctival injections of triamcinolone acetonide. Material and methods. Three patients with recurrent episcleritis, low efficacy of treatment with local steroid, non-steroidal anti-inflammatory drugs and a disease duration of more than 6 months were under observation. All were injected with a prepared solution of triamcinolone acetonide (diluted 1:1 with physiological solution 0.9%) subconjunctivally, once according to the original method. No othe

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Loucks, Anne B. "Physical Health of the Female Athlete: Observations, Effects, and Causes of Reproductive Disorders." Canadian Journal of Applied Physiology 26, S1 (2001): S176—S185. http://dx.doi.org/10.1139/h2001-052.

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This review begins by summarizing the state of knowledge about menstrual disorders in athletes at the turn of the 21st Century. It then highlights the most important developments of outstanding interest that have been reported in the 18 months since then. New observations of the characteristics of these disorders are followed by new reports of clinical consequences and recommendations for treatment, and discoveries about their physiological mechanism. In general, evidence is continuing to accumulate that exercise has no suppressive effect on the reproductive system beyond the impact of its ene

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Ruiz-Irastorza, Guillermo, and George Bertsias. "Treating systemic lupus erythematosus in the 21st century: new drugs and new perspectives on old drugs." Rheumatology 59, Supplement_5 (2020): v69—v81. http://dx.doi.org/10.1093/rheumatology/keaa403.

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Abstract Besides treating acute flares, the management of SLE should aim at preventing organ damage accrual and drug-associated harms, improving health-related quality of life and prolonging survival. At present, therapy is based on combinations of antimalarials (mainly HCQ), considered the backbone of SLE treatment, glucocorticoids and immunosuppressive drugs. However, these regimens are not universally effective and a substantial degree of damage can be caused by exposure to glucocorticoids. In this review we provide a critical appraisal of the efficacy and safety of available treatments as

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Pyrhönen, S., M. Hahka-Kemppinen, and T. Muhonen. "A promising interferon plus four-drug chemotherapy regimen for metastatic melanoma." Journal of Clinical Oncology 10, no. 12 (1992): 1919–26. http://dx.doi.org/10.1200/jco.1992.10.12.1919.

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PURPOSE The goal of this study was to determine the therapeutic efficacy and toxicity of a four-drug chemotherapy regimen combined with natural leukocyte interferon alfa (IFN-alpha) for metastatic melanoma. PATIENTS AND METHODS Between December 1988 and December 1991, 48 consecutive unselected patients with metastatic melanoma were entered onto this phase II study. Forty-five of these patients were assessable for response and 46 for toxicity. The four-drug chemotherapy regimen was as follows: dacarbazine (DTIC) 200 mg/m2 days 1 to 5, vincristine 1 mg/m2 days 1 and 4, bleomycin 15 mg days 2 and

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Akram, Muhammad, Abid Mahmood, Mohammed Khudhair Hasan, et al. "Tuberculosis in the 21st Century: Challenges in Diagnosis, Treatment, and Global Control." African Journal of Clinical Medicine and Pharmacy Research 2, no. 2 (2025): 324–30. https://doi.org/10.58578/ajcmpr.v2i2.5455.

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With an estimated 10 million cases and over one million fatalities annually, TB is still one of the most significant infectious illnesses affecting worldwide public health, mostly in low- and middle-income nations. Mainly affecting the lungs (pulmonary TB), Mycobacterium tuberculosis is a slow-growing, acid-fast bacillus that causes tuberculosis. However, it may also affect other organs, such as the lymph nodes, bones, central nervous system, and genitourinary tract. Due to a number of variables, including delayed diagnosis, poor treatment adherence, the emergence of drug-resistant strains, an

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Galustov, Kirill A. "Impact of the Urban Regime on the Urban Spatial Transformation of Saint Petersburg in the 21st Century (On the Example of Ecological and Eco-Cultural Conflicts)." Administrative Consulting, no. 12 (180) (June 7, 2023): 167–91. https://doi.org/10.22394/1726-1139-2023-12-167-191.

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Aim: Identification of the features of the impact of the urban regime dynamics on the transformation of the urban space of Saint Petersburg in the 21st century.Methods: Quantitative and qualitative methods of sociological research (expert survey, media content analysis, case analysis); math modeling (conversion of the conflict base into quantitative indicators, calculation of the scoring system and spatio-temporal models of the impact of the urban regime dynamics on the urban spatial transformation); mapping; typology. Results & Discussion: Empirical material was obtained on the basis of s

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Makhachashvili, Rusudan, Ivan Semenist, and Anna Bakhtina. "DIGITAL SKILLS DEVELOPMENT AND ICT TOOLS FOR FINAL QUALIFICATION ASSESSMENT: SURVEY STUDY FOR STUDENTS AND STAFF OF EUROPEAN AND ORIENTAL PHILOLOGY PROGRAMS." OPEN EDUCATIONAL E-ENVIRONMENT OF MODERN UNIVERSITY, no. 9 (2020): 54–68. http://dx.doi.org/10.28925/2414-0325.2020.9.5.

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The global pandemic and subsequent quarantine measures and restrictions have posed an array of challenges to the structure and procedure of university summative assessment process. Qualification assessment for Foreign Languages major programs in particular is a strict regimen process that involves different stages (oral and written exams, final project viva, internal and external review). Factors of societal change, that provide the backdrop for skillset critical transformation, crucial for the COVID-19 emergency educational framework are considered. The study premise is based on identificatio

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Go, Chzhizho. "Problems and Countermeasures to Solve Them in the System of Dance Education in Colleges and Universities in China." Scientific Research and Development. Socio-Humanitarian Research and Technology 12, no. 4 (2024): 96–103. http://dx.doi.org/10.12737/2306-1731-2024-12-4-96-103.

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The Chinese nation has a unique tradition of choreographic culture, characteristic of the Indochinese region. Consequently, dance is an obligatory phenomenon of culture, in which the aesthetics of the body, emotions and the nature of social relations of the Chinese are harmoniously correlated. It retains its popularity among students of colleges and universities, as it contributes to their comprehensive development. Therefore, dance education in colleges and universities is of great importance for every student and deserves constant development. By the beginning of the 21st century, the Chines

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Musiał, Kazimierz. "The integrative potential of science and research cooperation for suturing the Baltic Sea region in the 21st century." Rocznik Instytutu Europy Środkowo-Wschodniej 19, no. 3 (2021): 9–32. http://dx.doi.org/10.36874/riesw.2021.3.1.

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The aim of the article is to demonstrate how science and researchcooperation may help to reintegrate the Baltic region in the 21st century withthe participation of Russia. This is done through the analysis of documentsand strategies of Baltic Sea regionalism in the context of the regional knowledgeregime. Attention is paid to different positionalities of the regional actorsand their narratives. The theoretical framework is secured by an analysis ofcritical junctures drawing on case studies from the years 1989-91 and 2014 andthe subsequent reconfiguration of the power / knowledge nexus. The ana

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Haas, S. "The long path to NOAC." Phlebologie 45, no. 04 (2016): 245–51. http://dx.doi.org/10.12687/phleb2319-4-2016.

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SummaryThe discovery of anticoagulant drugs occurred at a time when the process of blood coagulation only had been roughly described and their mode of action was unknown. Nevertheless, heparin – which was discovered 100 years ago – and warfarin – which was developed in the 1920s – had taken off on a triumphal course which is unique in medical history. The synthesis of anticoagulants with targeted mode of action was only achieved at the end of the last century, e. g. the inhibitor of factor Xa fondaparinux or the recombinant production of the direct thrombin inhibitor hirudin, closely followed

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Dash, Pritilagna, Asokan R., Chandan Pradhan, and Jogamaya Pattnaik. "Efficacy of oral cryotherapy compared to normal saline mouth wash on reducing alkylating drug induced mucositis among cancer patients at selected tertiary care hospital, Bhubaneswar." F1000Research 14 (March 19, 2025): 310. https://doi.org/10.12688/f1000research.159833.1.

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Background The most prevalent, widely recognized, and challenging side effect experienced by cancer patients undergoing chemotherapy is mucositis, which results in considerable morbidity and has the potential to impede the treatment regimen and augment therapeutic costs. Therefore, a comparison between the two experimental interventions in the present study was performed to represent the effectiveness of different treatments or preventative measures. Aim To evaluate the efficacy of oral cryotherapy compared to normal saline mouthwash in reducing alkylating drug-induced mucositis among cancer p

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Padmaveer PS and Sandeep S Sagare. "A review on Ayurveda dietetics for Amlapitta (Gastroesophageal Reflux Disease) by different Ayurveda classical texts." Journal of Ayurveda and Integrated Medical Sciences 8, no. 11 (2023): 140–44. http://dx.doi.org/10.21760/jaims.8.11.21.

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Amlapitta could be a commonly experienced illness of Annavaha Srotasa (gastrointestinal system) depicted in different classical Ayurvedic writings that affects people of all ages, genders, regions, and climates. The 21st century is regarded as the modern era due to which bygone eating habits and life style is totally changed. Indulgence of food articles such as over processed, under processed and incompatible dietary preparations are the root cause of most of the non-communicable disorders now a days. Ritucharya (a seasonal regime) and Dinacharya (a diurnal regime) were some of the dos and don

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Irino, Tomoyuki, Hiroya Takeuchi, Masanori Terashima, Toshifumi Wakai, and Yuko Kitagawa. "Gastric Cancer in Asia: Unique Features and Management." American Society of Clinical Oncology Educational Book, no. 37 (May 2017): 279–91. http://dx.doi.org/10.1200/edbk_175228.

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Gastric cancer (GC) poses a burden to patients across the globe as the third leading cause of cancer deaths worldwide. Incidence of GC is particularly high in Asian countries, which is attributed to the prevalence of Helicobacter pylori (H. pylori) infection and has prompted the establishment of unique treatment strategies. D2 gastrectomy, which was established in the 1950s in Japan, has served as a gold standard for locally advanced GC for over half a century. Since the beginning of the 21st century, endoscopic resection (ER) techniques and minimally invasive laparoscopic surgery have greatly

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Faria, Maria J., Carla M. Lopes, José das Neves, and Marlene Lúcio. "Lipid Nanocarriers for Anti-HIV Therapeutics: A Focus on Physicochemical Properties and Biotechnological Advances." Pharmaceutics 13, no. 8 (2021): 1294. http://dx.doi.org/10.3390/pharmaceutics13081294.

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Since HIV was first identified, and in a relatively short period of time, AIDS has become one of the most devastating infectious diseases of the 21st century. Classical antiretroviral therapies were a major step forward in disease treatment options, significantly improving the survival rates of HIV-infected individuals. Even though these therapies have greatly improved HIV clinical outcomes, antiretrovirals (ARV) feature biopharmaceutic and pharmacokinetic problems such as poor aqueous solubility, short half-life, and poor penetration into HIV reservoir sites, which contribute to the suboptima

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Kasimovskaya, N. A. "Risk factors in a health model of nursing stuff." Kazan medical journal 100, no. 6 (2019): 980–84. http://dx.doi.org/10.17816/kmj2019-980.

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Aim. To study the behavioral trajectory of the lifestyle of students of medical colleges who studied in 20152016 and a health model formed by them. Methods. Using a sample (n=400) selected by a simple random method, the lifestyle and health model of students of medical colleges in Moscow in 20152016 were studied by sociological method based on descriptive statistics, correlation-regression and factor analysis. Results. Analysis of lifestyles of the students of medical colleges revealed the following behavioral risk factors: alcohol consumption (55.3%), eating improperly (54.5%), sm

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Chieloka, Okoli Solomon, and Onaga Phelomena. "Investigating an Outbreak of Newcastle Disease among Vaccinated and Unvaccinated Poultry Chicken." East African Journal of Agriculture and Biotechnology 8, no. 1 (2025): 38–46. https://doi.org/10.37284/eajab.8.1.2678.

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The burden of Newcastle disease may continue to increase due to non-adherence to poultry vaccination policies among some commercial poultry farmers. The purpose of this study was to investigate a suspected outbreak of Newcastle disease (ND) among clusters of vaccinated and unvaccinated poultry chickens. Poultry Farm (Farm Z) with 600 capacity deep litter pen (A and B) and capacity of 300 birds each procured two sets of poultry at 21 days of life from two separate farms (X and Y mixed layer & broiler) on the 2nd of May 2024. Pen A: was stocked with Layers of chicken from farm (X) poultry ch

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Korivi, Mallikarjuna, and Betty Revon Liu. "Novel and Practical Approaches to Manage Diet-induced Metabolic Disorders: Part-I." Current Pharmaceutical Design 26, no. 39 (2020): 4953–54. http://dx.doi.org/10.2174/138161282639201110165712.

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Metabolic syndrome (MetS) which is caused by poor dietary habits and sedentary behavior is a serious global health problem. MetS is a cluster of risk factors, represented by central obesity, hyperglycemia, dyslipidemia, and hypertension. In the 21st century, MetS and associated comorbidities, including obesity, diabetes and cardiovascular diseases, are the major threats to human health. Practical dietary strategies, nutritional bioactive compounds and a healthy lifestyle are claimed to be efficient in the management of one or more components of MetS. Nevertheless successful management of MetS

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Ergeshov, Atadzhan Е. "Tuberculosis in the Russian Federation: Situation, Challenges and Perspectives." Annals of the Russian academy of medical sciences 73, no. 5 (2018): 330–37. http://dx.doi.org/10.15690/vramn1023.

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Tuberculosis (TB) is a significant problem of public health both in Russia and abroad. About one third of the world’s population is infected with Mycobacterium tuberculosis. Every year more than 10 million new TB cases are registered in the world, and about 1.7 million people die from TB. In the Russian Federation, due to the measures taken by the Government and health authorities the epidemic TB situation has been noticeably improved since the sharp deterioration in the 90s of the last century. At the same time, the spread of drug-resistant TB and its low treatment effectiveness, the spread o

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Sartelli, Massimo, Corrado P. Marini, John McNelis, et al. "Preventing and Controlling Healthcare-Associated Infections: The First Principle of Every Antimicrobial Stewardship Program in Hospital Settings." Antibiotics 13, no. 9 (2024): 896. http://dx.doi.org/10.3390/antibiotics13090896.

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Antimicrobial resistance (AMR) is one of the main public health global burdens of the 21st century, responsible for over a million deaths every year. Hospital programs aimed at improving antibiotic use, referred to as antimicrobial stewardship programs (ASPs), can both optimize the treatment of infections and minimize adverse antibiotics events including the development and spread of AMR. The challenge of AMR is closely linked to the development and spread of healthcare-associated infection (HAIs). In fact, the management of patients with HAIs frequently requires the administration of broader-

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Ahmed, Tanveer, Omer Hassaan Aftab Ahmad, Muhammad Bilal, Sher Alam, Shirjeel Zaheer, and Zaid Gul. "Comparison of Efficacy of Sofosbuvir & Daclatasvir with Sofosbuvir and Velpatasvir in Achieving SVR in Patients of Chronic Hepatitis C with Genotype 3." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 1155–58. http://dx.doi.org/10.53350/pjmhs221641155.

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Background and Aim: Hepatitis C virus of chronic nature has been appreciated globally to be a major source of hepatic carcinomas and other abnormalities associated with liver function. The epidemiological data on the prevalence of the Hepatitis C virus shows a trend of 71 million people being affected by the disease globally with an annual mortality rate of 3.5 to 5 million death. Pakistan showed a prevalence of up to 8.2% which is among the most common incidents in countries. Since genotype 3 is the most common variant in Pakistan there remains a literature gap that evaluates the effectivenes

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IAVORSCHI, Constantin, Sofia ALEXANDRU, Stela KULCIȚKAIA, et al. "Achievements and topical issues in the field of prevention, diagnosis, and treatment of tuberculosis in children in the Republic of Moldova during the implementation of the “End tb strategy”." One Health & Risk Management 3, no. 3 (2022): 26–32. http://dx.doi.org/10.38045/ohrm.2022.3.04.

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Introduction. The fight against tuberculosis (TB) as an infectious and socially significant disease and the protection of children's health, representing one of the urgent problems of the 21st century, retain priority positions in national medicine.  Material and methods. Analysis of reporting statistical data on tuberculosis in children for 2016-2021 and the main sections of TB practice. Results. Epidemiological indicators are presented that characterize the burden of TB incidence cases (new cases and recurrences) in children, its dynamics, as well as the structure of clinical for

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Yana, Goncharuk. "LEGAL PRINCIPLES OF PARTICIPATION OF UKRAINIAN POLITICAL PARTIES IN THE ELECTION PROCESS." ISSN 2353-8406 Knowledge, Education, Law, Management 2020 № 2 (30) (December 12, 2020): 38–49. https://doi.org/10.5281/zenodo.4318796.

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 It has been found that in the 21st century, political parties play an important role in the political processes of society, forming political power in a representative democracy. Qualitative development of political parties is possible with proper legal support, which allows ruling and opposition political parties to participate in electoral processes on a democratic basis. It is determined that crucial for a proper understanding of the basic principles of political party participation in electoral processes is that they should in no way be seen as a means of imposing excessive rest

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Alekseev, A. L., and T. V. Alekseeva. "EFFECTIVENESS OF USING MULTIVITAMIN PREPARATIONS IN HYPOVITAMINOSIS IN PIGLETS." Scientific Life 16, no. 2 (2021): 236–42. http://dx.doi.org/10.35679/1991-9476-2021-16-2-236-242.

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For the normal vital activity of the animal body, a sufficient amount of vitamins is necessary, which are an integral part of the full functioning of the body, the absence of vitamins entails the development of hypovitaminosis and imbalance of the whole body. In pigs, unlike other species of animals, diseases caused by a lack of vitamins occur more often and are more acute. Prevention in hypovitaminosis is based on the use of various complex multivitamin drugs. The research was carried out on the basis of the enterprise LLC "Russian Pork, Razvilnoye" Peschanokopsky district. The object of the

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Palasanthiran, Pamela. "Mother-to-child transmission of HIV: positive impacts." Microbiology Australia 29, no. 4 (2008): 215. http://dx.doi.org/10.1071/ma08215.

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Mother-to-child-transmission (MTCT) of HIV remains the major mode of paediatric HIV infection. Advances in the prevention of MTCT over the past decade and a half represent a major public health achievement. Strategies to prevent MTCT are now the standard of care for countries rich enough to afford the interventions. As such, perinatally acquired HIV in countries like the USA and Europe is now a rare event. With clearly documented declines in MTCT rates in resource rich countries, the focus is shifting towards any downsides of these strategies in pregnant women and for fetuses exposed in utero

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Younas, Zohaib, Zia Ur Rehman Mashwani, Ilyas Ahmad, et al. "Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges." Molecules 28, no. 3 (2023): 1064. http://dx.doi.org/10.3390/molecules28031064.

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Bio-fortification is a new, viable, cost-effective, and long-term method of administering crucial minerals to a populace with limited exposure to diversified foods and other nutritional regimens. Nanotechnology entities aid in the improvement of traditional nutraceutical absorption, digestibility, and bio-availability. Nano-applications are employed in poultry systems utilizing readily accessible instruments and processes that have no negative impact on animal health and welfare. Nanotechnology is a sophisticated innovation in the realm of biomedical engineering that is used to diagnose and cu

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Alexyuk, Madina, Pavel Alexyuk, Yergali Moldakhanov, Kuralai Akanova, and Andrey Bogoyavlenskiy. "Evaluation of phage cocktail efficacy for controlling infections caused by pathogenic Escherichia coli in in vivo experiments." BIO Web of Conferences 100 (2024): 02004. http://dx.doi.org/10.1051/bioconf/202410002004.

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Colibacillosis is a common veterinary infection that causes huge economic losses to the livestock and poultry industry. Uncontrolled use of antibiotics has led to the emergence and spread of multidrug resistant bacteria and has reduced the effectiveness of standard treatment regimens for infectious diseases. This stimulated the renewed interest in bacteriophages among scientists since the beginning of the 21st century. Bacteriophages are widespread in nature and accompany bacteria in every environment they colonize, including the microbiota of warm-blooded animals. The purpose of the research

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Zhang, Yi, Jialu Zhang, Dongmei Li та ін. "A Cocktail of Lipid Nanoparticle-mRNA Vaccines Broaden Immune Responses against β-Coronaviruses in a Murine Model". Viruses 16, № 3 (2024): 484. http://dx.doi.org/10.3390/v16030484.

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Severe acute respiratory syndrome (SARS)-coronavirus (CoV), Middle Eastern respiratory syndrome (MERS)-CoV, and SARS-CoV-2 have seriously threatened human life in the 21st century. Emerging and re-emerging β-coronaviruses after the coronavirus disease 2019 (COVID-19) epidemic remain possible highly pathogenic agents that can endanger human health. Thus, pan-β-coronavirus vaccine strategies to combat the upcoming dangers are urgently needed. In this study, four LNP-mRNA vaccines, named O, D, S, and M, targeting the spike protein of SARS-CoV-2 Omicron, Delta, SARS-CoV, and MERS-CoV, respectively

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Moksnes, Magnus, and Fredrik H. Schjesvold. "The Impact of RVD or VCD Induction on Response 3 Months after First Line Autologous Transplant in Multiple Myeloma. a Single-Center Retrospective Analysis." Blood 132, Supplement 1 (2018): 3445. http://dx.doi.org/10.1182/blood-2018-99-113270.

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Abstract Introduction: The use of triple agent induction therapy before first line high-dose therapy (HDT) and autologous stem cell transplant (ASCT) in multiple myeloma is now considered standard of care. While thalidomide/bortezomib/dexamethasone (VTD) is the only induction regimen approved by EMA, both cyclophosphamide/bortezomib/dexamethasone (VCD) and lenalidomide/bortezomib/dexamethasone (RVD) are recommended in the most recent ESMO guidelines (Moreau et al., Annals of Oncology, 2017). Prospective comparisons of VCD and RVD are lacking. Cross-study comparisons show that the combinations

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De Lena, Mario, Mario Brandi, Alfredo Logroscino, Vito Lorusso, Angelo Paradiso, and Evaristo Maiello. "Intravenous Administration of Cyclophosphamide, Methotrexate and 5-Fluorouracil in Metastatic Breast Cancer. A Pilot Study." Tumori Journal 74, no. 1 (1988): 57–63. http://dx.doi.org/10.1177/030089168807400110.

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Sixty-two women with advanced breast cancer were admitted to a pilot study in which a modified CMF regimen was administered. Cyclophosphamide was administered i.v. at a dosage of 600 mg/m2 on the same day as fluorouracil (600 mg/m2/i.v.) and methotrexate (40 mg/m2/i.v.). The therapy was recycled on the 21st day and in the presence of myelosuppression, the administration of the drugs was delayed for 1-2 weeks recovery of the hematologic values. CR + PR were obtained in 42% of patients and no change in 32% (U.I.C.C. criteria). Metastases to soft tissues showed CR + PR in 55% of the cases, bone i

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Lin, Ming-Tai, Jiunn-Liang Ko, Te-Chung Liu, Pei-Tsen Chao, and Chu-Chyn Ou. "Protective Effect of D-Methionine on Body Weight Loss, Anorexia, and Nephrotoxicity in Cisplatin-Induced Chronic Toxicity in Rats." Integrative Cancer Therapies 17, no. 3 (2018): 813–24. http://dx.doi.org/10.1177/1534735417753543.

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D-methionine is a sulfur-containing amino acid that can act as a potent antioxidant. Anorexia and nephrotoxicity are side effects of cisplatin. The protective effects of D-methionine on cisplatin-induced anorexia and renal injury were investigated. The model of chronic cisplatin administration (5 mg/kg body weight) involved intraperitoneal injection on days 1, 8, and 15 and oral D-methionine (300 mg/kg body weight) coadministration daily for 20 days. On the 21st day of treatment, food intake and body weight in the cisplatin-treated group significantly decreased by 52% and 31%, respectively, wh

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Adilbay, D. G., G. B. Adilbaev, and D. N. Ahmetov. "Concurrent chemoradiotherapy of patients with locally advanced squamous cell carcinoma of the oral cavity (stage III, IV)." Journal of Clinical Oncology 27, no. 15_suppl (2009): e17034-e17034. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e17034.

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e17034 Background: Randomized trials have showed a good result of concurrent chemoradiotherapy in advanced SCC of the head and neck. But there are only few trials which evaluates separately the different sites of the head and neck. The aim was to evaluate the toxicity and efficacy of concurrent intra-arterial chemotherapy plus radiotherapy with altered fractionation in SCC of the oral cavity. Methods: 43 patients with previously untreated oral cavity SCC (T3–4N0–2M0) received concurrent chemoradiotherapy by followed scheme: first day intra-arterial chemotherapy: docetaxel - 80 mg/m2, cysplatin

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Prasad, Archana, and Anish Kumar. "IMPORTANCEOF NIDANPARIVARJANIN AMLAPITTAW.S.RTO HYPERACIDITY: A REVIEW." International Journal of Advanced Research 10, no. 10 (2022): 944–48. http://dx.doi.org/10.21474/ijar01/15564.

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All the disease can be prevented and managed through Nidanparivarjan along with proper sevan of PathyaApathya regimens mentioned in Ayurvedic Samhitas.Nidanparivarjan means avoidance of etiological factors of Amlapitta. which helps in prevention of Amlapitta in normal individual and management of Amlapitta taking medicationsin a diseased person.In Ayurveda it is believed that Agnimandya(Indigestion) is the root cause of all the disease Amlapittais one of the commonly occurring disease the major reason behind Amlapitta is faulty dietary habits and lifestyle. Amlapitta disease possess highly pre

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., Monika, and Rakesh Yadav. "Current Prospects: Drug acting against resistant Tuberculosis." International Journal of Membrane Science and Technology 10, no. 2 (2023): 2618–31. http://dx.doi.org/10.15379/ijmst.v10i2.2932.

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The most lethal disease tuberculosis is caused by Mycobacterium tuberculosis and the risk has worsened with the appearance of drug resistance, in particular multi drug resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). Antimicrobial resistance (AMR), is one of the most dominant health hazard that has emerged in the 21st century. This review embrace the drug resistance in MTB and inclusive overview of present phenotypic and molecular approaches for drug vulnerability testing, with particular attention to the methods endorsed and recommended by the WHO. “Drug resistance is an unav

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Merita, Limani. "Women's political participation: A comparative study of gender quota implementation in six Western Balkan countries." Journal of Social and Educational Research 2, no. 2 (2023): 23–32. https://doi.org/10.5281/zenodo.10440926.

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Women’s political participation has increased globally over the course of the 21st century. However, this positive development is less reflected in countries in development, as women continue to rely heavily on affirmative measures such as gender quotas to enter politics. The lack of women’s political participation disrupts human rights and undermines democracy. This study aims to provide a comparative analysis of gender quota regimens on women’s political participation in the six Western Balkans countries: Albania, Bosnia and Hercegovina, Kosovo, Montenegro, North Macedonia,

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ATUL, ATUL. "EVALUATION OF THE SAFETY AND EFFICACY OF T-AYU-HM PREMIUM AND ONION STEAM INHALATION IN MILD TO MODERATE COVID-19 PATIENTS." International Journal of Pharmaceutical Sciences and Drug Research 14, no. 02 (2020): 233–37. http://dx.doi.org/10.25004/ijpsdr.2022.140212.

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Background: Coronavirus disease (Covid-19) has impacted many nations' health care and their economic growth within no time. This Pandemic situation demands a safe and cost-effective treatment as early as possible to prevent any further suffering. Objective: To clinically evaluate the safety and efficacy of T-AYU-HM Premium Tablets (600mg) and Onion steam inhalation in mild to moderate Covid-19 patients. Methodology: The trial is an Open-label, Single-arm study conducted in mild to moderate level coronavirus patients. 30 participants infected by the coronavirus enrolled for the study, on provid

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