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Journal articles on the topic '26.3:79.0:30.609'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Faltas, Bishoy, Jane L. Liesveld, Michael Becker, Jainulabdeen J. Ifthikharuddin, and Gordon L. Phillips. "Salvage Autologous Hematpoeitic Stem Cell Transplants (AHSCT2) for Myeloma: Single Center Experience." Blood 116, no. 21 (2010): 4591. http://dx.doi.org/10.1182/blood.v116.21.4591.4591.

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Abstract Abstract 4591 Although the role of AHSCT1 is well established in multiple myeloma therapy, the role of the salvage (not “tandem”) AHSCT2 is less clear. However, most pts. undergo initial stem cell harvests with plans for eventual AHSCT2. To clarify the indications, the prognostic factors and the outcomes of AHSCT2 in relapsed myeloma, we analyzed our experience in 19 pts. (pts.) who underwent salvage AHSCT2 between the 1994–2008. Mean age at AHSCT1/2 was 54.58 (SD 7.96)/57.03 (SD 8.10) respectively; 15 (79.0%) were males. At the time of diagnosis, 7 (36.8%) pts. had ISS stage I, 6 (31

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2

Heyrman, RM, WA De Backer, JP Van Waeleghem, MJ Willemen, PA Vermeire, and ME De Broe. "Effect of oxygen administration on the breathing pattern during haemodialysis in man." European Respiratory Journal 2, no. 10 (1989): 972–76. http://dx.doi.org/10.1183/09031936.93.02100972.

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During haemodialysis (HD), allowing important CO2- unloading, an irregular breathing pattern (BP) is frequently observed. This has been attributed to a decrease in central chemoreceptor firing, with a greater contribution of the peripheral chemoreceptors in the chemical drive to breathe. To provide further evidence for these findings we studied five patients with end-stage renal failure in chronic HD. They underwent HD with a cuprophane membrane and acetate-containing dialysate. Ventilation was measured continuously using respiratory inductance plethysmography. Oxygen was administered for 30 m

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Guerra, Gage, Hayden Hofmann, Sina Sobhani, et al. "421 GPT-4 Artificial Intelligence Model Outperforms ChatGPT, Medical Students, and Neurosurgery Residents on Neurosurgery Written Board-Like Questions." Neurosurgery 70, Supplement_1 (2024): 128. http://dx.doi.org/10.1227/neu.0000000000002809_421.

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INTRODUCTION: Artificial intelligence (AI) and machine learning (ML) have transformed healthcare, with applications in various specialized medical fields. Neurosugery can benefit from AI in surgical planning, predicting patient outcomes, and analyzing neuroimaging data. GPT-4, an updated advanced language model by OpenAI with additional training parameters, has exhibited exceptional performance on standardized exams. METHODS: GPT-4's performance was examined on 643 Congress of Neurological Suregons (CNS) Self-Assessment Neurosurgery Exam (SANS) board-style questions from various neurosurgery s

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Colombo, Nicoletta, Domenica Lorusso, and Paolo Scollo. "Impact of Recurrence of Ovarian Cancer on Quality of Life and Outlook for the Future." International Journal of Gynecologic Cancer 27, no. 6 (2017): 1134–40. http://dx.doi.org/10.1097/igc.0000000000001023.

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ObjectiveOvarian cancer recurs in most patients, with a 5-year survival rate less than 30%. Quality of life is an increasingly important issue in patients with cancer, but there are limited data in women with recurrent ovarian cancer in this regard.Materials and MethodsWe used an ad hoc questionnaire to compare changes in health perceptions, burden of disease, and expectations for the future quality of life in women with and without recurrence of ovarian cancer. A total of 173 women were included, 116 with relapse and 57 without, undergoing follow-up in a routine clinical setting.ResultsSubsta

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Summaira Perveen, Sadia Khadim, Humaira Bashir, Hina Iqbal, Anza Shahzadi, and Syeda Ayesha Qamar. "Frequency of asymptomatic bacteriuria, causative pathogens and antibiotic sensitivity pattern in antenatal women." Professional Medical Journal 31, no. 04 (2024): 620–25. http://dx.doi.org/10.29309/tpmj/2024.31.04.7974.

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Objective: To determine the frequency of asymptomatic bacteriuria (ASB), causative pathogens and antibiotic sensitivity pattern in antenatal women. Study Design: Cross-sectional study. Setting: Department of Obstetrics and Gynaecology, Nishtar Hospital, Multan, Pakistan. Period: February 2022 to July 2023. Methods: A total of 110 women with singleton pregnancy with gestational age 13-42 weeks, and aged 18 to 40 years were included. Once the patients were enrolled, demographic characteristics (age, gestational age, parity (primiparous or multiparous), body mass index (BMI), place of living (rur

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Musa, HI, SM Jajere, NB Adamu, et al. "Prevalence of Tick Infestation in Different Breeds of Cattle in Maiduguri, Northeastern Nigeria." Bangladesh Journal of Veterinary Medicine 12, no. 2 (2014): 161–66. http://dx.doi.org/10.3329/bjvm.v12i2.21279.

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A survey study was conducted from June to December 2009 using standard parasitological procedures to determine the prevalence of tick infestation among cattle of different breeds in Maiduguri, Northeastern Nigeria. The tick species identified were Boophilus microplus, Amblyomma variegatum, Hyalomma spp., Rhipicephalus sanguineous and Ornithodorus spp. Of the 205 cattle examined, 63.4% (95% CI: 56.8 70.0) were tick infested. Males had a non significantly (P > 0.05) higher infestation rate of 63.4% (56.7 71.7) compared with the females 60.9% (46.8 75.0). Younger animals aged ? 3 years

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7

Bakkabulindi, Pamela, Solomon T. Wafula, Anthony Ssebagereka, et al. "Improving the last mile delivery of vaccines through an informed push model: Experiences, opportunities and costs based on an implementation study in a rural district in Uganda." PLOS Global Public Health 4, no. 10 (2024): e0002647. http://dx.doi.org/10.1371/journal.pgph.0002647.

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Developing countries face challenges in ensuring equitable, timely, and efficient vaccine availability at health facilities. In Uganda, the distribution of vaccines from district stores to the last-mile health facilities is hindered by an unpredictable and unreliable mixed push-pull delivery system. This system often results in poor vaccine management, stock-outs, and missed vaccination opportunities. This pilot study aimed to enhance the efficiency of last-mile vaccine delivery by implementing an informed push model. The specific goals were to improve vaccine lead time, standardize cold chain

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8

HONG, CHIH-CHUN, and FUSAO KONDO. "Detection, Quantitation, and Identification of Residual Aminopenicillins by High-Performance Liquid Chromatography after Fluorescamine Derivation." Journal of Food Protection 63, no. 10 (2000): 1421–25. http://dx.doi.org/10.4315/0362-028x-63.10.1421.

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A high-performance liquid chromatographic (HPLC) method with fluorescence detection after precolumn fluorescamine derivation was developed to detect residues of two aminopenicillins, amoxicillin (AMPC) and ampicillin (ABPC), in bovine serum. Proteins in serum samples spiked with each of these penicillins were precipitated with sodium tungstate and sulfuric acid, centrifuged, and removed by passage through a C18 solid-phase extraction cartridge. After precolumn treatment of the extraction products of AMPC and ABPC with fluorescamine solution, HPLC analysis with fluorescence spectrophotometric d

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9

Clark, Sean, Christopher Nagelli, Anthony DeNovio, et al. "FP5.8 Osteochondral Allograft and Autograft Transplantation for Femoral Head Defects: A Multicenter Study with a Mean 5-Year Follow-Up." Journal of Hip Preservation Surgery 12, Supplement_1 (2025): i15. https://doi.org/10.1093/jhps/hnaf011.046.

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Abstract Background: Osteochondral allograft and autograft transplantation for femoral head defects have emerged as promising treatments for concomitant cartilage and subchondral bone injuries in young patients. The purpose of this study was to evaluate the clinical and radiological outcomes of patients who underwent osteochondral allograft or autograft transplantation for femoral head defects and access any risk factors that may lead to conversion to THA. Methods: All patients who underwent osteochondral allograft or autograft transplantation for femoral head defects were analyzed. All patien

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10

Jie, He, Baohui Han, Yongyu Liu, et al. "Update of a phase III trial of adjuvant vinorelbine plus cisplatin (NP) versus NP plus endostar (NPE) in patients with completely resected stage IB-IIIA non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 30, no. 15_suppl (2012): e18013-e18013. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e18013.

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e18013 Background: Adjuvant chemotherapy demonstrated a 5-15% benefit in 5-year survival in early-stage NSCLC. Endostar,a recombinant human Endostatin, could inhibit tumor angiogenesis. In a phase III trial, the addition of Endostar to NP regimen resulted in higher response rate, clinical benefit rate and longer median time to progression compared with NP alone in advanced NSCLC patients. Methods: Completely resected patients (stage IB-IIIA) were randomized to receive adjuvant NP plus Endostar (arm A, Vinorelbine 25mg/m2 on d1 and d8 plus Cisplatin 80 mg/m2 intravenously plus Endostar 7.5mg/m2

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Nfongeh, Joseph Fuh, Lucy Nwakaego Okonkwo, Dantani Dauda Odonye, et al. "Phenotypic Characterization and Plasmid DNA Profiling of Multidrug-Resistant Escherichia coli and Staphylococcus aureus in Wastewater Effluents From Healthcare Environments in Lafia, Nigeria." Journal of Advances in Environmental Health Research 11, no. 4 (2023): 237–45. http://dx.doi.org/10.34172/jaehr.1309.

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Background: Multidrug-resistant Escherichia coli and Staphylococcus aureus are frequent culprits of severe healthcare-associated infections and have been identified as significant pollutants in hospital settings. The research into plasmids as potential carriers for transferring new resistance genes among clinical pathogens has been quite constrained. This study was conducted to determine the extent of multidrug resistance and the presence of plasmids in E. coli and S. aureus isolates derived from wastewater effluents at healthcare institutions in Lafia, Nigeria. Methods: A total of 231 effluen

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Ali-Fehmi, R., M. Cote, M. H. Arabi, et al. "Endometrial carcinoma (EC) in women 35 years of age or younger." Journal of Clinical Oncology 25, no. 18_suppl (2007): 16000. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.16000.

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16000 Background: Although the majority of women with EC are postmenopausal, 25% are under the age of 50 years at the time of diagnosis. The aim of this study is to describe the demographic and survival data for women presenting with EC at age 35 years or younger (YOY). Design: Patients with a diagnosis of EC were identified from the Surveillance, Epidemiology, and End Results (SEER) cancer database from 1988 to 2003. Demographic and pathologic data were collected. Chi-square and t-tests were used to examine differences between the younger and older women, and survival analyses were performed

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Marks, Jennifer Aline, Laura Gosa Barrett, Minhee Kang, Sharon O'Brien, and Stephen V. Liu. "Outcomes with initiation of inpatient immunotherapy." JCO Oncology Practice 20, no. 10_suppl (2024): 7. http://dx.doi.org/10.1200/op.2024.20.10_suppl.7.

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7 Background: Immune checkpoint inhibitors (ICIs) have transformed cancer care; however, studies establishing their benefit have been primarily conducted in robust patients (pts) with good performance status. Administration of ICI to hospitalized pts remains a subject of debate. While there is often a desire to reverse clinical course in patients who are acutely ill, previous studies show minimal benefit from anticancer therapy near the end of life with the potential for toxicity. While ICI are generally better tolerated than traditional cancer therapies, the median time to response ranges fro

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Palamarchuk, Inna. "INFLUENCE OF TECHNOLOGY ELEMENTS ON TEMPERATURE AND SOIL MOISTURE FOR ZUCCHINI GROWING IN THE CONDITIONS OF THE FOREST-STEPPE OF THE RIGHT BANK OF UKRAINE." Agriculture and Forestry, no. 2 (May 25, 2021): 178–91. http://dx.doi.org/10.37128/2707-5826-2021-2-15.

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The results of researches of influence of mulching of soil and water-retaining granules Akvod on temperature and humidity of soil in the conditions of Forest-steppe of right-bank Ukraine are resulted. An increase in soil temperature and humidity was revealed with the use of black agrofiber mulching materials and perforated black polyethylene film, which is 1.3 and 2.6 ° C higher than the variant where soil mulching was not used. When mulching the soil with black agrofiber and perforated black polyethylene film, the soil moisture was 78.1–79.0 %, which is 14.5 and 15.4 % more than the control.

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15

Weber, Jeffrey S., Richard D. Carvajal, Inderjit Mehmi, et al. "ARTISTRY-6: Nemvaleukin alfa monotherapy in patients with advanced mucosal and cutaneous melanoma." Journal of Clinical Oncology 41, no. 16_suppl (2023): TPS9592. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.tps9592.

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TPS9592 Background: Despite improved outcomes in melanoma with the introduction of checkpoint inhibitors (CPIs), ≈50% of patients do not respond. A subset of responders ultimately progress and have limited treatment options, underscoring a high unmet need for novel treatments with durable benefit. Patients with mucosal melanoma exhibit response rates and progression-free survival ≈2 times lower than those with cutaneous melanoma. Nemvaleukin alfa (nemvaleukin, ALKS 4230) is a novel, engineered cytokine that selectively binds to the intermediate-affinity interleukin-2 receptor complex to prefer

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16

Prasad, Vinod K., Adam Medizabal, Suhag H. Parikh, et al. "Analysis of the Cellular Components of the Graft and Clinical Characteristics of 159 Children with Lysosomal and Peroxisomal Disorders (LSD) Undergoing Unrelated Umbilical Cord Blood Transplantation at a Single Center." Blood 110, no. 11 (2007): 336. http://dx.doi.org/10.1182/blood.v110.11.336.336.

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Abstract Background: Allogeneic bone marrow transplantation from related and unrelated donors leads to improvement in longevity and quality of life due to replacement of missing enzyme and engraftment of donor-derived glial cells in patients with LSD. Recently, unrelated umbilical cord blood transplant (UCBT) has yielded encouraging results but due to the rarity of LSDs, there has never been a large series of patients transplanted at a single center. Methods: Between 1995 and 2007, 159 consecutive LSD patients received unrelated UCBT at Duke after busulfan, cyclophosphamide, and antithymocyte

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Hajek, Roman, Lenka Zahradova, Evzen Gregora, et al. "The Reduced Intensity Cvd Regimen: A Good Option with Well Balanced Efficacy/Toxicity Ratio for Elderly Patients with Poor Status Performance." Blood 112, no. 11 (2008): 3699. http://dx.doi.org/10.1182/blood.v112.11.3699.3699.

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Abstract Background: Bortezomib (Velcade) based regimens became a part of standard treatment in multiple myeloma (MM). Further optimization, focused on the favourable efficacy/toxicity ratio, is essential mainly for elderly patients (pts) and pts with poor performance status. These pts usually do not tolerate full dose of bortezomib and neuropathy in combination with severe fatigue are the most pronounced toxicities resulting in premature interruption of the treatment. As final consequence, these patients cannot fully benefit from the strong anti-myeloma potential of bortezomib. In this trial,

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Yamaguchi, Hiroki, Masaki Iino, Yutaka Imamura, et al. "Efficacy and Safety of Avatrombopag in Japanese Adults with Chronic Immune Thrombocytopenia: Open-Label, Phase 3 Study." Blood 144, Supplement 1 (2024): 5426. https://doi.org/10.1182/blood-2024-205479.

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Introduction: Avatrombopag (AVA) is an orally administered thrombopoietin receptor (TPO-RA) agonist widely approved for the treatment of adults with chronic immune thrombocytopenia (ITP). This study aims to assess AVA in Japanese patients with chronic ITP. Methods: This Phase 3, multicenter, open-label study (a 26-week core phase [completed] followed by an extension phase [ongoing until market authorization in Japan]) evaluates the efficacy and safety of AVA (initial dose 20 mg/day) in Japanese adults (aged ≥18 years) with chronic ITP (≥12 months duration), insufficient response to prior treat

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Sharathkumar, Anjali, Brandy Trawinski, J. Michael Soucie, Anne Greist, Craig Haddix, and Amy D. Shapiro. "Cardiovascular Disease in Patients with Hemophilia: Single Centre Experience." Blood 112, no. 11 (2008): 2272. http://dx.doi.org/10.1182/blood.v112.11.2272.2272.

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Abstract Background: Cardiovascular disease (CVD) is at epidemic levels (37%, Heart Disease and Stroke Statistics, 2008 Update) in the US and is also affecting hemophilia patients. Conflicting reports exist concerning the potential protective effect of hemophilia on the occurrence of CVD. Objective: To evaluate the prevalence and risk factors of CVD events in patients with hemophilia ≥40 years old. Methods: This cross sectional study included all patients with hemophilia followed at Indiana Hemophilia and Thrombosis Center (IHTC) from January 2004 to June 2008. The following data were obtained

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Brown, Jennifer R., Tadeusz Robak, Paolo Ghia, et al. "Efficacy and Safety of Zanubrutinib in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) with del(17p): Follow-up Results from Arm C of the SEQUOIA (BGB-3111-304) Trial." Blood 136, Supplement 1 (2020): 11–12. http://dx.doi.org/10.1182/blood-2020-134280.

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Background: Patients (pts) with CLL/SLL whose tumor exhibits the deletion of chromosome 17p13.1 [del(17p)] have an unfavorable prognosis and respond poorly to standard chemoimmunotherapy. Zanubrutinib (BGB-3111) is an investigational, next-generation Bruton tyrosine kinase (BTK) inhibitor. In the ASPEN study of pts with Waldenström macroglobulinemia, zanubrutinib was associated with important safety advantages compared to ibrutinib, especially regarding cardiovascular toxicity (Blood; in press). The initial results from Arm C of the SEQUOIA (BGB-3111-304) trial of zanubrutinib in a large cohor

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Gordon-Evans, Wanda J., K. Helena Montin, Christopher P. Ober, Jessi L. Coryell, and Andrea E. Castilla. "Canine mitral valve size as measured by computed tomography." American Journal of Veterinary Research, October 27, 2022, 1–4. http://dx.doi.org/10.2460/ajvr.22.05.0085.

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Abstract OBJECTIVE To measure the mitral annulus in dogs. Our hypothesis was that mitral measurement would be possible and consistent among observers using CT. SAMPLE Thoracic CT scans of dogs without known heart disease. PROCEDURES Five trained investigators measured 4 aspects of the mitral valve and the fourth thoracic vertebrae (T4) length using multiplanar reformatting tools. Ten randomly chosen animals were measured by all investigators to determine interobserver reliability. RESULTS There were 233 CT scans eligible for inclusion. Dogs weighed 2 to 96 kg (mean, 28.1 kg), with a variety of

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Tam, Constantine S., Tadeusz Robak, Paolo Ghia, et al. "Zanubrutinib monotherapy for patients with treatment naïve chronic lymphocytic leukemia and 17p deletion." Haematologica, October 13, 2020, 0. http://dx.doi.org/10.3324/haematol.2020.259432.

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Patients with chronic lymphocytic leukemia or small lymphocytic lymphoma whose tumors carry deletion of chromosome 17p13.1 [del(17p)] have an unfavorable prognosis and respond poorly to standard chemoimmunotherapy. Zanubrutinib is a selective next-generation Bruton tyrosine kinase inhibitor. We evaluated the safety and efficacy of zanubrutinib 160 mg twice daily in treatment-naïve patients with del(17p) disease enrolled in a dedicated, nonrandomized cohort (Arm C) of the phase 3 SEQUOIA trial. A total of 109 patients (median age, 70 years; range, 42 – 86) with centrally confirmed del(17p) were

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Zhang, J., A. Stevenson, A. Zhou, et al. "1118 Epidemiology of Tibial Fractures, a UK Major Trauma Centre Perspective." British Journal of Surgery 110, Supplement_7 (2023). http://dx.doi.org/10.1093/bjs/znad258.696.

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Abstract Aim There is no recent large UK-based study on the epidemiology of tibial fractures. In our study, we report incidence and factors associated with tibial fractures treated at a Level I Trauma Centre over a 7-year period. Method We gathered data on fracture locations, age, gender, BMI, Charlson Comorbidity Index (CCI), and treatment options of all tibial fractures treated at a major trauma centre during the seven years from January 2015 to January 2022. The incidence of fracture types was calculated, as well as associations different fracture locations had with demographics, and their

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Wang, Mingda, Guojun Qian, Hongmei Xiao, et al. "Prognostic significance of postoperative serological incomplete conversion of AFP and PIVKA-II after hepatic resection for hepatocellular carcinoma: a multicenter analysis of 1755 patients." Oncologist, June 22, 2024. http://dx.doi.org/10.1093/oncolo/oyae139.

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Abstract Background The value of serum biomarkers, particularly alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II), gains increasing attention in prognostic evaluation and recurrence monitoring for patients with hepatocellular carcinoma (HCC). This study investigated the implications of serological incomplete conversion (SIC) of these 2 biomarkers as prognostic indicators for long-term outcomes after HCC resection. Methods A multicenter observational study was conducted on a cohort of HCC patients presenting with AFP (&gt;20 ng/mL) or PIVKA-II (&am

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Triana, Jairo, Ariana Lott, Naina Rao, et al. "Poster 251: Patients who Undergo Bilateral Medial Patellofemoral Ligament Reconstruction Return to Sport at a Similar Rate to Unilaterals: A Matched Cohort Study." Orthopaedic Journal of Sports Medicine 11, no. 7_suppl3 (2023). http://dx.doi.org/10.1177/2325967123s00230.

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Objectives: Lateral patellar instability is a debilitating condition not only to athletes, but also a broad range of highly active individuals. Many of these patients experience instability symptoms bilaterally. Medial patellofemoral ligament reconstruction (MPFLR) is indicated to prevent future recurrence and ideally facilitate a complete return to sports (RTS). While RTS has been examined following MPFLR, the rate and timing of RTS in patients that undergo MPFLR bilaterally is unknown. The purpose of this study is to compare patients who have received bilateral MPFLR to a matched unilateral

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