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Journal articles on the topic '2DE'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Zhan, Xianquan, Biao Li, Xiaohan Zhan, Hartmut Schlüter, Peter R. Jungblut, and Jens R. Coorssen. "Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level." Proteomes 7, no. 4 (2019): 36. http://dx.doi.org/10.3390/proteomes7040036.

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Two-dimensional gel electrophoresis (2DE) is an important and well-established technical platform enabling extensive top-down proteomic analysis. However, the long-held but now largely outdated conventional concepts of 2DE have clearly impacted its application to in-depth investigations of proteomes at the level of protein species/proteoforms. It is time to popularize a new concept of 2DE for proteomics. With the development and enrichment of the proteome concept, any given “protein” is now recognized to consist of a series of proteoforms. Thus, it is the proteoform, rather than the canonical

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La Canna, Giovanni, Iside Scarfò, Irina Arendar, et al. "Targeting Alcohol Septal Ablation in Patients with Obstructive Hypertrophic Cardiomyopathy Candidates for Surgical Myectomy: Added Value of Three-Dimensional Intracoronary Myocardial Contrast Echocardiography." Journal of Clinical Medicine 10, no. 10 (2021): 2166. http://dx.doi.org/10.3390/jcm10102166.

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Background: Myocardial contrast two-dimensional echocardiography (MC-2DE) is widely used to address alcohol septal ablation (ASA) in obstructive hypertrophic cardiomyopathy (HCM). Owing to its limited cut-planes, MC-2DE may inaccurately identify the contrast misplacement associated with an unsuccessful or complicated ASA outcome. Objective: The aim of this study was to assess the added value of myocardial contrast three-dimensional echocardiography (MC-3DE) compared with MC-2DE to identify the appropriate matching between the target septal zone (TSZ) and coronary artery branch for safe and lon

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Buccheri, Sergio, Ines Monte, Sarah Mangiafico, Vera Bottari, Stefano Leggio, and Corrado Tamburino. "Feasibility, Reproducibility, and Agreement between Different Speckle Tracking Echocardiographic Techniques for the Assessment of Longitudinal Deformation." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/297895.

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Background.Left ventricular (LV) longitudinal deformation can be assessed with new echocardiographic techniques like triplane echocardiography (3PE) and four-dimensional echocardiography (4DE). We aimed to assess the feasibility, reproducibility, and agreement between these different speckle-tracking techniques for the assessment of longitudinal deformation.Methods. 101 consecutive subjects underwent echocardiographic examination. 2D cine loops from the apical views, a triplane view, and an LV 4D full volume were acquired in all subjects. LV longitudinal strain was obtained for each imaging mo

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Nabeshima, Yosuke, Tetsuji Kitano, and Masaaki Takeuchi. "Reliability of left atrial strain reference values: A 3D echocardiographic study." PLOS ONE 16, no. 4 (2021): e0250089. http://dx.doi.org/10.1371/journal.pone.0250089.

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Background Standard apical four-chamber and two-chamber views often maximize the long-axis of the left ventricle, resulting in artifactitious foreshortening of the left atrium (LA), which may overestimate LA longitudinal reservoir strain (LALS). We compared LALS values between 2D echocardiography (2DE) and 3D echocardiography (3DE) in healthy subjects to determine whether 2DE speckle tracking analysis overestimates the reference value of LALS. Methods and results In this study, 4 types of cohorts were included: 1. 105 normal subjects (retrospectively), 2. 53 patients with cardiovascular diseas

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Xing, Yuanyuan, Hongyuan Xue, and Yuquan Ye. "Automated Quantitative Technique of 3D Cardiac Anatomical Model for Evaluating Left Ventricular Systolic Function in Patients with Myocardial Infarction." Journal of Biomaterials and Tissue Engineering 10, no. 8 (2020): 1143–48. http://dx.doi.org/10.1166/jbt.2020.2415.

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This study intends to use 3D cardiac anatomical model automatic quantitative technique Heart Model (HM) to assess left ventricular systolic function in patients with myocardial infarction. Thirty patients with myocardial infarction (case group) and 32 healthy individuals (control group) were enrolled in this study.M-mode echocardiography (MME), two-dimensional echocardiography (2DE), 3D cardiac anatomical model (HM) and real-time 3D echocardiography (3DE) were used to collect echocardiographic images. Left ventricular systolic function parameters (LVEDV), left ventricular end-systolic volume (

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Shrestha, Manish, Urmila Shakya, Poonam Sharma, et al. "Is Two Dimensional Echocardiography sufficient for selection of device for successful transcatheter closure of Patent Ductus Arteriosus in Children?" Nepalese Heart Journal 18, no. 2 (2021): 45–48. http://dx.doi.org/10.3126/njh.v18i2.40404.

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Background and Aims: Two dimensional transthoracic echocardiography (2DE) is widely used for detecting congenital heart disease and is possible to obtain precise measurement of Patent ductus arteriosus (PDA) for device selection required for transcatheter closure. Primary aim of the study is to determine whether echocardiographic assessment alone can be used for selection of device for transcatheter closure of PDA. Methods: Children with PDA and planned for transcatheter intervention were included in this cross-sectional study of one year. PDA was assessed with 2DE and prediction of devi

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Bushljetikj, Oliver, and Ljubica Georgievska-Ismail. "Comparison of Two-Dimensional and Three-Dimensional Echocardiography in Determination of Left Ventricle Volumes and Ejection Fraction in Adult Population." PRILOZI 38, no. 3 (2017): 105–12. http://dx.doi.org/10.2478/prilozi-2018-0011.

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Abstract Introduction: Left ventricle (LV) volumes and ejection fraction (EF) determined with two-dimensional echocardiography (2DE) and three-dimensional echocardiography (3DE) show significant differences.The aim of this study is to determine the agreement of the measurements of LV volumes and EF with 2DE and 3DE in the general adult population, with preserved LV systolic function. Material and methods: In 52 subjects, older than 65 years, LV end-diastolic volume index (EDVi), end-systolic volume index (ESVi) and EF were measured with 2DE and 3DE according to the official recommendations, an

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Penso, Marco, Remo Antonio Ranalletta, Mauro Pepi, et al. "Comparison between Automatic and Semiautomatic System for the 3D Echocardiographic Multiparametric Evaluation of RV Function and Dimension." Journal of Clinical Medicine 11, no. 15 (2022): 4528. http://dx.doi.org/10.3390/jcm11154528.

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Background: The right ventricle (RV) plays a pivotal role in cardiovascular diseases and 3-dimensional echocardiography (3DE) has gained acceptance for the evaluation of RV volumes and function. Recently, a new artificial intelligence (AI)–based automated 3DE software for RV evaluation has been proposed and validated against cardiac magnetic resonance. The aims of this study were three-fold: (i) feasibility of the AI-based 3DE RV quantification, (ii) comparison with the semi-automatic 3DE method and (iii) assessment of 2-dimensional echocardiography (2DE) and strain measurements obtained autom

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Szymczyk, Tobias, Odile Sauzet, Lech J. Paluszkiewicz, et al. "Non-invasive assessment of central venous pressure in heart failure: a systematic prospective comparison of echocardiography and Swan-Ganz catheter." International Journal of Cardiovascular Imaging 36, no. 10 (2020): 1821–29. http://dx.doi.org/10.1007/s10554-020-01889-3.

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Abstract Assessing hemodynamics, especially central venous pressure (CVP), is essential in heart failure (HF). Right heart catheterization (RHC) is the gold-standard, but non-invasive methods are also needed. However, the role of 2-dimensional echocardiography (2DE) remains uncertain, and 3-dimensional echocardiography (3DE) is not always available. This study investigated standardized and breathing-corrected assessment of inferior vena cava (IVC) volume using echocardiography (2DE and 3DE) versus CVP determined invasively using RHC. Sixty consecutive HF patients were included (82% male, age 5

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Oliveira, Bruno M., Jens R. Coorssen, and Daniel Martins-de-Souza. "2DE: The Phoenix of Proteomics." Journal of Proteomics 104 (June 2014): 140–50. http://dx.doi.org/10.1016/j.jprot.2014.03.035.

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Tadic, Marijana, Sanja Ilic, Nada Kostic, Zorica Caparevic, and Vera Celic. "Subclinical Hypothyroidism and Left Ventricular Mechanics: A Three-Dimensional Speckle Tracking Study." Journal of Clinical Endocrinology & Metabolism 99, no. 1 (2014): 307–14. http://dx.doi.org/10.1210/jc.2013-3107.

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Context: Subclinical hypothyroidism (SHT) is associated with left ventricular (LV) remodeling. The LV mechanics has not been previously assessed by two- and three-dimensional (2DE and 3DE) speckle tracking imaging in the SHT patients. Objectives: The objective of the study was to investigate LV mechanics by 2DE and 3DE speckle tracking in the SHT patients and evaluate the influence of levothyroxine therapy on LV remodeling. Design: We conducted a prospective study. All SHT patients received levothyroxine therapy and were followed up for 1 year after the euthyroid state had been achieved. Setti

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Noszczyńska, Magdalena, Karolina Łakomy, Krzysztof Nowacki, and Zofia Piotrowska-Seget. "A High Manganese-Tolerant Pseudomonas sp. Strain Isolated from Metallurgical Waste Heap Can Be a Tool for Enhancing Manganese Removal from Contaminated Soil." Applied Sciences 10, no. 16 (2020): 5717. http://dx.doi.org/10.3390/app10165717.

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Manganese (Mn) is widely used in industry. However, its extensive applications have generated a great amount of manganese waste, which has become an ecological problem and has led to a decrease in natural resources. The use of microorganisms capable of accumulating Mn ions from contaminated ecosystems offers a potential alternative for the removal and recovery of this metal. The main aim of this work was an investigation of removal potential of Mn from soil by isolated bacterial. For this purpose, eleven bacterial strains were isolated from the soil from metallurgical waste heap in Upper Siles

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Chňapek, Milan, Zdenka Galova, Želmíra Balážová, et al. "APPLICATION OF TWO-DIMENSIONAL ELECTROPHORESIS AND MASS SPECTROMETRY FOR THE DETECTION OF ALLERGENS IN SELECTED VARIETIES OF WHEAT, OATS AND BUCKWHEAT." Journal of microbiology, biotechnology and food sciences 13, no. 1 (2023): e9934. http://dx.doi.org/10.55251/jmbfs.9934.

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The number of people suffering from food allergies and intolerances has been increasing in recent years and cereal proteins are the most common food allergens. Pseudocereals represent perspective alternative in nutrition with a positive effect on the human body. The aim of the work was to analyze the proteome of selected varieties of wheat (Triticum aestivum L.), oats (Avena sativa) and buckwheat (Fagopyrum esculentum Moench.) using two-dimensional electrophoresis (2DE) and mass spectrometry in order to detect the presence of potentially allergenic proteins. Using the PDQuest program, 221 prot

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OM, Anil. "Evaluation of Ejection Fraction in Patients with cardiac Resynchronization Therapy by Two and Three Dimensional Echocardiography." Journal of Institute of Medicine Nepal 36, no. 3 (2014): 58–63. http://dx.doi.org/10.59779/jiomnepal.572.

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Introduction: Since assessment of left ventricular ejection fraction (LVEF) is crucial for evaluation of patients with cardiac resynchronization therapy (CRT) device both for selection of potential candidates for CRT as well as assessing outcome of therapy, we compared LVEF in patients with CRT device by two dimensional and three dimensional echocardiography. Methods: Two dimensional echocardiography (2DE) was performed first with CRT device on. LVEF obtained by modified biplane Simpson’s Rule. Then real time three dimensional echocardiography (3DE) was performed by (iE 33, PHILIPS Machine). P

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Naryzhny, Stanislav. "Towards the Full Realization of 2DE Power." Proteomes 4, no. 4 (2016): 33. http://dx.doi.org/10.3390/proteomes4040033.

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Rodrigues, Silas P., Sophie Alvarez, Emily G. Werth, et al. "Multiplexing strategy for simultaneous detection of redox-, phospho- and total proteome – understanding TOR regulating pathways in Chlamydomonas reinhardtii." Analytical Methods 7, no. 17 (2015): 7336–44. http://dx.doi.org/10.1039/c5ay00521c.

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Schiau, Călin, Daniel-Corneliu Leucuța, Sorin Marian Dudea, and Simona Manole. "Magnetic Resonance Assessment of Ejection Fraction Versus Echocardiography for Cardioverter-Defibrillator Implantation Eligibility." Biology 10, no. 11 (2021): 1108. http://dx.doi.org/10.3390/biology10111108.

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Background: The aim of this study was to investigate the potential impact of performing two-dimensional echocardiography (2DE) compared to cardiovascular magnetic resonance (CMR) for left ventricular ejection fraction (LVEF) on implantable cardioverter defibrillator (ICD) eligibility. Methods: A prospective cohort of 166 consecutive patients with nonischemic cardiomyopathy (NICM) was designed to compare transthoracic 2DE and CMR imaging. Results: Echocardiography measurements have important differences and large limits of agreement compared to CMR, especially when assessing ventricle volumes,

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Vantaggiato, Lorenza, Claudia Landi, Enxhi Shaba, Daniela Rossi, Vincenzo Sorrentino, and Luca Bini. "Protein Extraction Methods Suitable for Muscle Tissue Proteomic Analysis." Proteomes 12, no. 4 (2024): 27. http://dx.doi.org/10.3390/proteomes12040027.

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Muscle tissue is one of the most dynamic and plastic tissues of the mammalian body and covers different roles, such as force generation and metabolic control. Muscular proteomics provides an important opportunity to reveal the molecular mechanisms behind muscle pathophysiology. To ensure successful proteomic analysis, it is necessary to have an efficient and reproducible protein extraction method. This study aimed to evaluate the efficacy of two different extraction protocols of muscle samples for two-dimensional gel electrophoresis. In particular, mouse muscle proteins were extracted by an SD

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Ronzhina, N. L., E. S. Zorina, M. G. Zavialova, O. K. Legina, and S. N. Naryzhny. "Variability of haptoglobin beta-chain proteoforms." Biomeditsinskaya Khimiya 70, no. 2 (2024): 114–24. http://dx.doi.org/10.18097/pbmc20247002114.

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Existing knowledge on changes of the haptoglobin (Hp) molecule suggests that it may exist in multiple proteoforms, which obviously exhibit different functions. Using two-dimensional electrophoresis (2DE) in combination with mass spectrometry and immunodetection, we have analyzed blood plasma samples from both healthy donors and patients with primary grade IV glioblastoma (GBM), and obtained a detailed composite 2DE distribution map of β-chain proteoforms, as well as the full-length form of Hp (zonulin). Although the total level of plasma Hp exceeded normal values in cancer patients (especially

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Jessie, K., J. J. Jayapalan, K. C. Ong, et al. "Aberrant proteins in the saliva of patients with oral squamous cell carcinoma." Electrophoresis 34, no. 17 (2014): 2495–502. https://doi.org/10.1002/elps.201300107.

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Confirmation of oral squamous cell cancer (OSCC) currently relies on histological analysis, which does not provide clear indication of cancer development from precancerous lesions. In the present study, whole saliva proteins of patients with OSCC (n = 12) and healthy subjects (n = 12) were separated by 2DE to identify potential candidate biomarkers that are much needed to improve detection of the cancer. The OSCC patients' 2DE saliva protein profiles appeared unique and different from those obtained from the healthy subjects. The patients' saliva 1-antitrypsin (AAT) and haptoglobin (HA

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Meyer, M., and F. H. Herrmann. "Diversity of Glycoprotein Deficiencies in Glanzmann’s Thrombasthenia." Thrombosis and Haemostasis 54, no. 03 (1985): 626–29. http://dx.doi.org/10.1055/s-0038-1660085.

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SummaryThe platelet proteins of 9 thrombasthenic patients from 7 families were analysed by high resolution two-dimensional gel electrophoresis (HR-2DE) and crossed immunoelectrophoresis (CIE). In 7 patients both glycoproteins (GPs) IIb and Ilia were absent or reduced to roughly the same extent. In two related patients only a trace of GP Ilb-IIIa complex was detected in CIE, but HR-2DE revealed a glycopeptide in the position of GP Ilia in an amount comparable to type II thrombasthenia. This GP Ilia-like component was neither recognized normally by anti-GP Ilb-IIIa antibodies nor labeled by surf

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Ruitenbeek, K. "Nyoirin Kannon, rolschildering, Japan, 2de kwart 14de eeuw." Rijksmuseum Bulletin 37, no. 3 (1989): 151–53. https://doi.org/10.52476/trb.20672.

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Ning, Fen, Xiaolin Wu, and Wei Wang. "Exploiting the potential of 2DE in proteomics analyses." Expert Review of Proteomics 13, no. 10 (2016): 901–3. http://dx.doi.org/10.1080/14789450.2016.1230498.

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Tsugu, Toshimitsu, Adriana Postolache, Raluca Dulgheru, et al. "Echocardiographic reference ranges for normal left ventricular layer-specific strain: results from the EACVI NORRE study." European Heart Journal - Cardiovascular Imaging 21, no. 8 (2020): 896–905. http://dx.doi.org/10.1093/ehjci/jeaa050.

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Abstract Aims To obtain the normal range for 2D echocardiographic (2DE) measurements of left ventricular (LV) layer-specific strain from a large group of healthy volunteers of both genders over a wide range of ages. Methods and results A total of 287 (109 men, mean age: 46 ± 14 years) healthy subjects were enrolled at 22 collaborating institutions of the EACVI Normal Reference Ranges for Echocardiography (NORRE) study. Layer-specific strain was analysed from the apical two-, three-, and four-chamber views using 2DE software. The lowest values of layer-specific strain calculated as ±1.96 standa

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Sljivic, Aleksandra, Milena Pavlovic Kleut, Vera Celic, Aleksandar N. Neskovic, Ivan Nesic, and Tatjana Gazibara. "How Right is the Right Ventricle in Predicting Cardiac Mortality in Cardiac Failure: A 6-year Prospective Cohort Study." Journal of Cardiovascular Echography 34, no. 2 (2024): 50–56. http://dx.doi.org/10.4103/jcecho.jcecho_13_24.

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Aim: Two-dimensional speckle tracking echocardiography (2D-STE) and three-dimensional echocardiography (3DE) may overcome many limitations of the conventional 2D echocardiography (2DE) in assessing right ventricular (RV) function. We sought to determine whether characteristics of the right atrium and right ventricle as measured by 2D-STE and 3DE are associated with cardiac mortality in patients with ischemic heart failure, over a 6-year follow-up. Materials and Methods: The inclusion criteria were ischemic cardiomyopathy with left ventricular ejection fraction of <40% diagnosed using standa

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Naser, Nabil, Ivan Stankovic, and Aleksandar Neskovic. "The Reliability of Automated Three-Dimensional Echocardiography-HeartModelA.I. Versus 2D Echocardiography Simpson Methods in Evaluation of Left Ventricle Volumes and Ejection Fraction in Patients With Left Ventricular Dysfunction." Medical Archives 76, no. 4 (2022): 259. http://dx.doi.org/10.5455/medarh.2022.76.259-266.

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Background: Two-dimensional echocardiography (2DE) Simpson methods is the most frequently used imaging modality to assess Left ventricular ejection fraction (LVEF). LVEF is an important predictor of morbidity and mortality in a wide range of patients and clinical scenarios. Despite its importance in prognosis and clinical decision making, most echocardiography laboratories currently determine EF primarily by visual estimation, which is highly experience-dependent and sensitive to intra- and inter-observer variability and suboptimal accuracy and repeatability. Over the last decade, 3-dimensiona

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Navakauskienė, Rūta, Sandra Baronaitė, Dalius Matuzevičius, et al. "Comparative Proteomic Assessment of Normal vs. Polyhydramnios Amniotic Fluid Based on Computational Analysis." Biomedicines 10, no. 8 (2022): 1821. http://dx.doi.org/10.3390/biomedicines10081821.

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Mass spectrometry-based proteomics have become a valued tool for conducting comprehensive analyses in amniotic fluid samples with pathologies. Our research interest is the finding and characterization of proteins related to normal vs. polyhydramnios (non-immune hydrops) pregnancy. Proteomic analysis was performed on proteins isolated from fresh amniotic fluid samples. Proteins were fractionated by 2DE using a different pI range (pI 3–11, pI 4–7) and analyzed with MALDI-TOF-MS. Furthermore, by using computational analysis, identified proteins in protein maps specific to normal vs. polyhydramnio

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Gurzun, Maria, Silviu Stanciu, Adrian Gabara, and Adrian Ionescu. "3D echo in everyday life: Could it reset our threshold for interventions?" Romanian Journal of Military Medicine 122, no. 3 (2019): 36–41. http://dx.doi.org/10.55453/rjmm.2019.122.3.6.

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Background Left ventricular ejection fraction (LVEF), the single most important metric in cardiology, is the cornerstone on which prognosis is estimated and costly decisions such as whether to implant an ICD are based. LVEF is most often assessed by 2D echocardiography (2DE), although 3D echocardiography (3DE) has been shown repeatedly to be more accurate. Aim of the study. We set out to assess whether using 3DE would reclassify the severity of LV impairment in patients with LVEF < 35% by 2DE. Setting. Tertiary cardiac centre serving a population of one million, and performing approximately

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LEE, JIANN-DER, and WEI-CHUN CHEN. "A NOVEL SCHEME FOR REGISTRATION OF TWO DIMENSIONAL GEL ELECTROPHORESIS IMAGES." Biomedical Engineering: Applications, Basis and Communications 18, no. 04 (2006): 158–66. http://dx.doi.org/10.4015/s1016237206000269.

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The research of proteomics is becoming one of important tasks in biological medical research after genomics. The first step to perform the protein analysis is to analyze gel electrophoresis images. In this paper, a novel scheme for registration of 2D gel electrophoresis images is proposed. First, we move one 2DE image along the x-axis and y-axis directions, overlap it on the second 2DE image and then calculate the mutual information of these two images. Repeat this procedure, we can find out the best registration result when the maximum mutual information is achieved. Next, the spot detection

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Garzon Esguerra, Carolina, Nathalie Charpak, Flor Matilde Muñoz Avendaño, Mayra J. Floriano Parra, and Martha E. Giron Giron. "Impacto nutricional de un minimercado mensual en niños prematuros y/o de bajo peso al nacer." Revista de Salud Pública 22, no. 5 (2020): 1–8. http://dx.doi.org/10.15446/rsap.v22n5.87207.

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Objetivos Evaluar el impacto nutricional de un minimercado mensual de alto valor nutricional entregado, mediante charlas educativas, a familias de recién nacidos prematuros y/o de bajo peso al nacer (BPN), en el marco de los Programas Madre Canguro (PMC), en Bogotá y Cundinamarca; asimismo, identificar los factores de riesgo que predisponen la aparición de la desnutrición (<-2DE).Métodos Estudio observacional, descriptivo y prospectivo de una cohorte de 392 niños inscritos en 10 PMC que presentan en su seguimiento un riesgo alimenticio o una desnutrición confirmada provenientes de familias

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Lestuzzi, Chiara, Davide Stolfo, Antonino De Paoli, et al. "Cardiotoxicity from Capecitabine Chemotherapy: Prospective Study of Incidence at Rest and During Physical Exercise." Oncologist 27, no. 2 (2022): e158-e167. http://dx.doi.org/10.1093/oncolo/oyab035.

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Abstract Background Physical activity may increase the risk of cardiotoxicity (myocardial ischemia, major arrhythmias) of 5-Fluorouracil, but this risk has never been investigated for its prodrug capecitabine. Patients and Methods One hundred and ninety-two consecutive patients undergoing capecitabine chemotherapy from December 1, 2010 through July 31, 2016 were prospectively evaluated. The baseline evaluation included electrocardiography (ECG) and echocardiography (2DE); a follow-up evaluation, including ECG and exercise stress testing (2DE in case of ECG abnormalities), was done after ≥10 da

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LIN, Qiong-Wen, Wu-Gang WANG, Wei-Chun WU, and Hao WANG. "Left atrial minimum volume by real-time three-dimensional echocardiography as an indicator of diastolic dysfunction." Chinese Medical Journal 126, no. 22 (2013): 4227–31. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20130465.

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Background Left atrial (LA) maximum volume is becoming a prognostic biomarker for left ventricular (LV) diastolic dysfunction. However, we assessed LV diastolic function by measuring LA phasic volumes using real-time three-dimensional echocardiography (RT3DE) in patients with stable coronary artery disease (CAD). Methods Sixty-five stable CAD patients with normal LV ejection fraction (LVEF) were divided into three groups according to degree of coronary stenosis: control (n=15) with <50% stenosis as control group, mildS (n=25) with mild stenosis (50%-70%) and severeS (n=25) with >70% sten

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Atici, A., R. Asoglu, H. Ali Barman, and Ö. Faruk Baycan. "Impact of Multimodality Imaging on the Diagnosis of Left Ventricular Apical Thrombus in Patients after Anterior MI." European Heart Journal 42, Supplement_1 (2021). http://dx.doi.org/10.1093/eurheartj/ehab724.092.

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Abstract Background The presence of the left ventricle (LV) apical thrombus is one of the most critical complications of anterior myocardial infarction. Due to the high risk of systemic embolization, the determination of LV apical thrombus (LVAT) is essential. Purpose We aimed to compare the Two-Dimensional Echocardiography (2DE), contrast-2DE and Real-time Three-Dimensional Echocardiography (RT-3DE) in the diagnosis of LVAT and determine which imaging modality is superior. Methods The study was designed as a prospective cohort study, and 161 patients were included. Patients with low ejection

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Mazzanti, A., K. Addetia, R. Maragna, et al. "P3685Can 3D echocardiography give a contribute to the diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)?" European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz745.0539.

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Abstract Background The diagnosis of ARVC is based on the structural assessment of the heart with 2D echocardiography (2DE) and cardiovascular MRI (CMR) to detect the presence of global and segmental right ventricular (RV) abnormalities. Little is known about the diagnostic value of 3D echocardiography (3DE) in ARVC. The aim of this study was to assess whether a combination of 2DE and 3DE could replace 2DE and CMR combination with similar diagnostic accuracy in patients with suspected ARVC. Methods Thirty-nine subjects (59% males, 47±15 years, 41% with desmosomal mutations) with suspected or c

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Bouwer, Nathalie I., Crista Liesting, Marcel J. M. Kofflard, et al. "2D-echocardiography vs cardiac MRI strain: a prospective cohort study in patients with HER2-positive breast cancer undergoing trastuzumab." Cardiovascular Ultrasound 19, no. 1 (2021). http://dx.doi.org/10.1186/s12947-021-00266-x.

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Abstract Background We aimed to study the predictive value of early two-dimensional echocardiography (2DE) speckle tracking (ST) for left ventricular ejection fraction (LVEF) changes during trastuzumab treatment for HER2-positive breast cancer. Methods HER2-positive breast cancer patients receiving trastuzumab, with or without anthracycline, underwent 2DE-ST at baseline and after 3 and 6 months (m) trastuzumab. Cardiac magnetic resonance (CMR) imaging (with ST) was performed at baseline and 6 m. We studied the correlation between 2DE-ST- and CMR-derived global longitudinal strain (GLS) and glo

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Bouwer, NI, C. Liesting, MJM Kofflard, et al. "2D-echocardiography vs cardiac MRI strain using deep learning: a prospective cohort study in patients with HER2-positive breast cancer undergoing trastuzumab." European Heart Journal - Cardiovascular Imaging 22, Supplement_1 (2021). http://dx.doi.org/10.1093/ehjci/jeaa356.118.

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Abstract Funding Acknowledgements Type of funding sources: Private hospital(s). Main funding source(s): Promotiefonds Albert Schweitzer Hospital Background Subclinical cardiotoxicity due to trastuzumab could be recognized by repeated measurements of global longitudinal/radial strain (GLS/GRS) which could be performed with cardiac magnetic resonance (CMR) or two-dimensional speckle tracking echocardiography (2DE-ST). Although CMR is the gold standard for cardiac function evaluation, it is not used for cardiac monitoring. 2DE-ST might be a reasonable alternative. Purpose To study the predictive

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Previtero, M., N. Ruozi, G. Sammarco, et al. "P275 Feasibility and accuracy of the automated quantification of two- and three-dimensional left ventricular ejection fraction and its role in the arrhythmic risk stratification of organic heart disease." European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (2020). http://dx.doi.org/10.1093/ehjci/jez319.132.

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Abstract BACKGROUND New automated approaches for left heart chamber quantification based on adaptive analytics algorithms have been introduced for both two- (2DE) and three-dimensional (3DE) echocardiography. These algorithms measure a left ventricular ejection fraction (LVEF) and reduce the intra- and inter-observer variability associated with the conventional manual tracing of LV endocardial borders. However, the clinical utility of these algorithms in the sudden cardiac death (SCD) risk stratification of patients with organic heart disease remains to be clarified. PURPOSE We sought to test

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Volpato, V., P. Ciampi, R. Johnson, et al. "Routine use of automated strain analysis and 3D echocardiography provides a more comprehensive assessment of cardiac chambers than conventional 2D echocardiography and is time-saving." European Heart Journal - Cardiovascular Imaging 23, Supplement_1 (2022). http://dx.doi.org/10.1093/ehjci/jeab289.128.

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Abstract Funding Acknowledgements Type of funding sources: None. Background. In most laboratories three-dimensional echocardiography (3DE) and longitudinal strain (Lstrain) analysis are not part of the routine studies. Although these modalities have been shown to provide additional clinical information and prognostic value compared to conventional two-dimensional echocardiography (2DE), their acquisition and analysis are perceived as being time-consuming. Recently, new automated tools have been developed to perform accurate, fast and reproducible analyses of heart chambers’ geometry and functi

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Addetia, Karima, Andrea Mazzanti, Riccardo Maragna, et al. "Value of 3D echocardiography in the diagnosis of arrhythmogenic right ventricular cardiomyopathy." European Heart Journal - Cardiovascular Imaging, September 3, 2022. http://dx.doi.org/10.1093/ehjci/jeac172.

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Abstract Aims The 2010 Task Force Criteria (TFC) require that both right ventricular (RV) regional wall-motion abnormalities (WMA) and specific RV size cut-offs be met in order to fulfil one of the major criterion for arrhythmogenic right ventricular cardiomyopathy (ARVC) diagnosis. Currently, 2D echocardiography (2DE) and cardiovascular magnetic resonance imaging (cMRI) are used to determine if these criteria are met. Little is known about the diagnostic value of 3D echocardiography (3DE) in ARVC. The aim of this study was to determine whether a combination of 2DE-3DE is non-inferior to the c

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Juergensen, Stephan, Christine Springston, Michael J. Bunker, Phillip Moore, and Shafkat Anwar. "Abstract 11887: High Agreement Between 2D and 3D Echocardiography in Measuring Dimensions of the Patent Ductus Arteriosus in Infants." Circulation 144, Suppl_1 (2021). http://dx.doi.org/10.1161/circ.144.suppl_1.11887.

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Introduction: The patent ductus arteriosus (PDA) is a common lesion in infants. Two-dimensional echocardiography (2DE) is standard for PDA imaging. Three-dimensional echocardiography (3DE) is often used for complex anatomy and for procedural planning. Very limited data exist on use of 3DE of the PDA in infants despite its value in planning interventions. We aim to determine the agreement between 2DE and 3DE in measuring PDAs in infants. Hypothesis: Significant agreement exists between 2DE and 3DE for PDA measurements. Methods: Infants with a known PDA underwent 2DE and 3DE imaging by an IRB-ap

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Albinmousa, Zakariya, Lan-Chau Kha, Alessia D. Carlo, et al. "Abstract 14692: Evaluation of Subaortic Right Ventricular Function in ccTGA: How Do Echocardiography Parameters Compare to CMR?" Circulation 132, suppl_3 (2015). http://dx.doi.org/10.1161/circ.132.suppl_3.14692.

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Background: Subaortic right ventricular (RV) functional assessment in patients with congenitally corrected transposition of the great arteries (ccTGA) is important for both long-term outcome and as an indication for tricuspid valve replacement. Cardiac magnetic resonance (CMR) imaging is considered the reference standard for assessment of subaortic RV systolic function. However, two-dimensional echocardiography (2DE) remains the most frequently used imaging modality in clinical practice. Objective: To compare 2DE and CMR parameters of RV function in patients with ccTGA. Methods: We identified

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Pilania, Rakesh Kumar, Pallavi L. Nadig, Suprit Basu, et al. "Congenital anomalies of coronary artery misdiagnosed as coronary dilatations in Kawasaki disease: A clinical predicament." World Journal of Clinical Pediatrics 14, no. 1 (2025). https://doi.org/10.5409/wjcp.v14.i1.99177.

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BACKGROUND 2D-echocardiography (2DE) has been the primary imaging modality in children with Kawasaki disease (KD) to assess coronary arteries. AIM To report the presence and implications of incidental congenital coronary artery anomalies that had been misinterpreted as coronary artery abnormalities (CAAs) on 2DE. METHODS Records of children diagnosed with KD, who underwent computed tomography coronary angiography (CTCA) at our center between 2013-2023 were reviewed. We identified 3 children with congenital coronary artery anomalies in this cohort on CTCA. Findings of CTCA and 2DE were compared

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Rella, V., C. Delcea, A. Clement, et al. "Left ventricular mass by three-dimensional echocardiography is associated with myocardial replacement fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy." European Heart Journal - Cardiovascular Imaging 26, Supplement_1 (2025). https://doi.org/10.1093/ehjci/jeae333.355.

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Abstract Background In hypertrophic cardiomyopathy (HCM) patients, quantification of left ventricular (LV) mass carries important prognostic implications. Two-dimensional echocardiography (2DE) has limited accuracy for LV mass calculation, due to plane position errors, geometric assumptions and asymmetric distribution of LV hypertrophy in HCM. Purpose We aimed to explore: (1) the accuracy of three-dimensional echocardiography (3DE) vs 2DE to quantify LV mass in HCM compared to cardiac magnetic resonance (CMR); (2) the relationship of 3DE LV mass with non-sustained ventricular tachycardia (NSVT

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Fisicaro, Samantha, Denisa Muraru, Sorina Mihaila Baldea, et al. "920 ASSOCIATION OF OUTCOME WITH LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION MEASURED WITH TWO-AND THREE-DIMENSIONAL ECHOCARDIOGRAPHY IN PATIENTS REFERRED FOR ROUTINE, CLINICALLY INDICATED STUDIES." European Heart Journal Supplements 24, Supplement_K (2022). http://dx.doi.org/10.1093/eurheartjsupp/suac121.242.

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Abstract Background LV volumes and LVEF measured by 3DE are more accurate and repeatable than those calculated with 2DE. However, the added prognostic value of 3DE LV volumes and EF remains to be clarified. Objectives To analyze if the left ventricular (LV) volumes and ejection fraction (EF) measured by three-dimensional echocardiography (3DE) have an incremental prognostic value over measurements obtained from two-dimensional echocardiography (2DE) in patients referred to a high-volume echocardiography laboratory. Methods We measured LV volumes and EF using both 2DE and 3DE in 725 consecutive

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"The Comparison Of Measurements On Chest X-Ray For Patients With Pectus Deformity." Internet Journal of Thoracic and Cardiovascular Surgery 5, no. 2 (2003). http://dx.doi.org/10.5580/2de.

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Muraru, Denisa, Sorina Mihaila Baldea, Davide Genovese, et al. "Association of outcome with left ventricular volumes and ejection fraction measured with two- and three-dimensional echocardiography in patients referred for routine, clinically indicated studies." Frontiers in Cardiovascular Medicine 9 (December 22, 2022). http://dx.doi.org/10.3389/fcvm.2022.1065131.

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ObjectivesWe sought to analyze if left ventricular (LV) volumes and ejection fraction (EF) measured by three-dimensional echocardiography (3DE) have incremental prognostic value over measurements obtained from two-dimensional echocardiography (2DE) in patients referred to a high-volume echocardiography laboratory for routine, clinically-indicated studies.MethodsWe measured LV volumes and EF using both 2DE and 3DE in 725 consecutive patients (67% men; 59 ± 18 years) with various clinical indications referred for a routine clinical study.ResultsLV volumes were significantly larger, and EF was lo

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Memis, H., S. Mihaila Baldea, D. Mihalcea, et al. "Short period of training in 3D echocardiography provides good feasibility and reproducibility of right ventricular assessment in heart failure." European Heart Journal - Cardiovascular Imaging 24, Supplement_1 (2023). http://dx.doi.org/10.1093/ehjci/jead119.226.

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Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): PROHEART 3D. Background Right ventricular (RV) dysfunction is an independent risk factor for increased mortality and morbidity. Standard approach for assessing is 2-dimensional echocardiography (2DE). However, 2DE is prone to errors due to increased variability of the anatomical cut-planes and geometrical assumptions due to the complex triangular and "wrapped-around" RV shape. Meanwhile, 2DE reflects mainly the RV longitudinal function, at the expense of the radial and glo

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Al Saikhan, L., C. Park, T. Tillin, et al. "P2444Comparison of 3D and 2D echocardiography-derived indices of left ventricular function and structure to predict long-term mortality in the general population: Southall And Brent Revisited (SABRE) study." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0776.

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Abstract Background Three-dimensional echocardiography (3DE) may have advantages over two-dimensional echocardiography (2DE) for the assessment of left ventricular (LV) function and structure. However, studies comparing 3DE and 2DE-derived indices in relation to mortality are limited, particularly in the general population. Purpose We examined associations between 2DE and 3DE-derived LV ejection fractions (LVEF) and volumes for all-cause mortality in a population-based sample. Methods A total of 899 individuals (age, 69.6±6.1 years; 77.5%male) from the SABRE study, a UK-based tri-ethnic commun

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Liu, B., W. Wu, Z. Liu, H. Wang, J. He, and C. Xiong. "P4363The predictive capacity of two- and three-dimensional echocardiography detected right ventricular strain in disease severity of pre-capillary pulmonary hypertension." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz745.0768.

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Abstract Background Pulmonary hypertension (PH) patients have poor prognosis due to progressive right ventricular (RV) dysfunction. As a low-cost and non-invasive tool, echocardiography is by far the most widely used technique to investigate the RV structure and function in PH patients. Recent studies showed that RV longitudinal strain (RVLS) measured by two- or three-dimensional echocardiography (2DE, 3DE) was correlated with RV function parameters and have the potential to predict the prognosis of PH patients. However, few studies have compared the value of 2DE- and 3DE- RVLS to predict dise

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Florescu, Diana Ruxandra, Luigi Paolo Badano, Michele Tomaselli, et al. "314 Automated left atrial volume measurement by two-dimensional speckle-tracking echocardiograpy. Feasibility, accuracy, and reproducibility." European Heart Journal Supplements 23, Supplement_G (2021). http://dx.doi.org/10.1093/eurheartj/suab132.020.

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Abstract Aims A by-product of left atrial (LA) strain analysis is the automated measurement of LA maximal volume (LAVmax), which may decrease the time of echocardiography reporting, and increase the reproducibility of the LAVmax measurement. However, the automated measurement of LAVmax by two-dimensional speckle-tracking analysis (2DSTE) has never been validated. Accordingly, we sought to: (i) assess the feasibility of automated LAVmax measurement by 2DSTE; (ii) compare the automated LAVmax by 2DSTE with conventional two-dimensional (2DE) biplane and three-dimensional echocardiography (3DE) me

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