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Relevant bibliographies by topics / 3-(aryl)-1-phenyl-1H-pyrazole-4-carbaldehyde

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Journal articles

Academic literature on the topic '3-(aryl)-1-phenyl-1H-pyrazole-4-carbaldehyde'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "3-(aryl)-1-phenyl-1H-pyrazole-4-carbaldehyde"

1

A, Kumar Maddineni, Rao Chunduri V, and Raju Begari N. "Synthesis and Characterization of Novel Mono Carbonyl Curcumin Analogues of Pyrazole Derivatives." Der Pharma Chemica 13, no. 1 (2021): 6. https://doi.org/10.5281/zenodo.13644078.

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(E)-4-aryl-1-phenyl-1H-pyrazol-4-yl)but-3-en-2-one derivatives were (4a-d) synthesized by the condensation of 3-aryl-1-phenyl-1H-pyrazole-4- carbaldehyde derivatives (3a-d) with acetone in the presence of sodium hydroxide. Compounds (4a-d) on condensation with different aldehydes give mono carbonyl curcumin analogues (MACs) of pyrazole derivatives (6a-x) in good yield.

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2

Vora, J. J., S. B. Vasava, K. C. Parmar, S. K. Chauhan, and S. S. Sharma. "Synthesis, Spectral and Microbial Studies of Some Novel Schiff Base Derivatives of 4-Methylpyridin-2-amine." E-Journal of Chemistry 6, no. 4 (2009): 1205–10. http://dx.doi.org/10.1155/2009/247209.

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Schiff base derivatives ofN-{(1E)-[3-(mono or di-substituted aryl)-1-phenyl-1H-pyrazol-4-yl]methylene{-4-methylpyridin-2-amine were synthesized by the acid catalyzed condensation of 3-(mono- or di- substituted aryl)-1-phenyl-1H-pyrazole-4-carbaldehyde derivatives with 4-methylpyridin-2-amine. Schiff base derivatives were characterized by FT-IR,1H-NMR, Mass spectral analysis and elemental analysis. All the synthesized compounds have been screened for their antimicrobial activities by using broth dilution method.

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3

Ramadan, El Sayed, Essam M. Sharshira, Ramadan I. El Sokkary, and Noussa Morsy. "Synthesis and antimicrobial evaluation of some heterocyclic compounds from 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehydes." Zeitschrift für Naturforschung B 73, no. 6 (2018): 389–97. http://dx.doi.org/10.1515/znb-2018-0009.

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AbstractA new series of chalcones, pyrazolinyl-pyrazoles, pyrazole-4-carbaldehyde oximes, pyrazole-4-carbonitriles, 5-pyrazolyl-1,2,4-triazolidine-3-thiones, and Knoevenagel condensation products was synthesized from 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehydes. Most reactions were carried out either without solvent or in the presence of water as a green solvent. The structure of synthesized compounds was characterized by spectral and elemental analysis. The synthesized compounds were tested in vitro for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida a

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4

Bhila, Varun G., Yogita L. Chovatiya, Chirag V. Patel, Rakesh R. Giri, and Dinkar I. Brahmbhatt. "A Convergent Approach for the Synthesis of New Pyrazolyl Bipyridinyl Substituted Coumarin Derivatives as Antimicrobials." International Letters of Chemistry, Physics and Astronomy 40 (October 2014): 1–16. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.40.1.

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Some new 3-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl) acryloyl] coumarins 3a-f were synthesized (coumarin chalcones) by the condensation of various 3-acetyl coumarins 1 and appropriate 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehyde 2. These coumarin chalcones 3a-f were then employed for the synthesis of pyrazolyl bipyridinyl substituted coumarins 7a-f, 8a-f, and 9a-f under Krohnke’s reaction condition. The characterization of all the synthesized compounds was carried out by elemental analysis, IR, 1H-NMR, 13C-NMR, DEPT-135 and mass spectral analysis. In addition to that, in vitro antimicrobial competenc

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5

Bhila, Varun G., Yogita L. Chovatiya, Chirag V. Patel, Rakesh R. Giri, and Dinkar I. Brahmbhatt. "A Convergent Approach for the Synthesis of New Pyrazolyl Bipyridinyl Substituted Coumarin Derivatives as Antimicrobials." International Letters of Chemistry, Physics and Astronomy 40 (October 23, 2014): 1–16. http://dx.doi.org/10.56431/p-y6404d.

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Some new 3-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl) acryloyl] coumarins 3a-f were synthesized (coumarin chalcones) by the condensation of various 3-acetyl coumarins 1 and appropriate 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehyde 2. These coumarin chalcones 3a-f were then employed for the synthesis of pyrazolyl bipyridinyl substituted coumarins 7a-f, 8a-f, and 9a-f under Krohnke’s reaction condition. The characterization of all the synthesized compounds was carried out by elemental analysis, IR, 1H-NMR, 13C-NMR, DEPT-135 and mass spectral analysis. In addition to that, in vitro antimicrobial competenc

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6

Hitesh, B. Vala, Upadhayay Jatin, and Rajyaguru Cheatana. "Synthesis, Characterization and Antimicrobial Activity of Some New Dihydropyridine Derivatives." Pharmaceutical and Chemical Journal 7, no. 6 (2020): 1–5. https://doi.org/10.5281/zenodo.13956338.

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Synthesis  of 4-(3-(aryl)–1–phenyl-1<em>H</em>–pyrazol–4–yl)-3,5–dimethyl-1,4,7,8–tetrahydro dipyrazolo [3,4-b:4',3'-e] pyridine by the reaction of different substituted 3-(aryl)–1-phenyl-1<em>H</em>-pyrazole-4-carbaldehyde with 2 mole of 3-methyl-1<em>H</em>-pyrazol-5(4<em>H</em>)-one in presence of ammonium acetate and methanol as a solvent. The constitution of all the synthesized compounds has been characterized by using IR, MASS,<sup> 1</sup>H<sup> </sup>NMR spectroscopy. All synthesized compounds were screened for their antimicrobial ac

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7

Shreekanth, Tharangini K., Hemmige S. Yathirajan, Balakrishna Kalluraya, Sabine Foro, and Christopher Glidewell. "Order versus disorder in two isomorphous pyrazolone-substituted diethyl propanedioates prepared using a three-component one-pot reaction under solvent-free conditions." Acta Crystallographica Section E Crystallographic Communications 76, no. 10 (2020): 1605–10. http://dx.doi.org/10.1107/s2056989020011676.

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Two new substituted propanedioate esters have been synthesized using a three-component solvent-free thermal reaction between diethyl propanedioate (diethyl malonate), 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde and an aryl azide, forming two new C—C bonds in a single step. The products diethyl (RS)-2-[(4-bromophenyl)(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)methyl]propanedioate, C24H25BrN2O5 (I), and diethyl (RS)-2-[(4-chlorophenyl)(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)methyl]propanedioate, C24H25ClN2O5 (II), are isomorphous, with Z′ = 2 in space group P21/n

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8

Kurnool, Aravind, Karunasree Merugu, Pachipulusu Shravya, and P. Malleswarareddy. "Synthesis, Biological Evaluation and Docking Studies of 1,2,4,5-Tetrasubstituted Imidazoles as Antibacterial Agents: Use of Niobia Supported Heteropoly Tungstate as an Efficient Reusable Catalyst." Asian Journal of Chemistry 33, no. 10 (2021): 2423–29. http://dx.doi.org/10.14233/ajchem.2021.23181.

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The synthesis of novel 1,2,4,5-tetrasubstituted imidazoles was carried out in a single molecular motif using niobia supported heteropoly tungstate as a mild and efficient reusable catalyst. The condensation of 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehyde, aromatic amine, benzil, ammonium acetate and heteropoly tungstate supported on niobia was achieved under both conventional and non-conventional conditions. The employed protocol provides significant advantages, as it exhibits a remarkable catalytic activity on recovery, excellent yields and excellent reaction efficacy within short reaction time

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9

Orrego Hernandez, Jessica, Jaime Portilla, Justo Cobo, and Christopher Glidewell. "Two different products from the reaction of 1-aryl-5-chloro-3-methyl-1H-pyrazole-4-carbaldehyde with cyclohexylamine when the aryl substituent is phenyl or pyridin-2-yl: hydrogen-bonded sheetsversusdimers." Acta Crystallographica Section C Structural Chemistry 71, no. 5 (2015): 363–68. http://dx.doi.org/10.1107/s2053229615006403.

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Cyclohexylamine reacts with 5-chloro-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde to give 5-cyclohexylamino-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde, C16H20N4O, (I), formed by nucleophilic substitution, but with 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde the product is (Z)-4-[(cyclohexylamino)methylidene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one, C17H21N3O, (II), formed by condensation followed by hydrolysis. Compound (II) crystallizes withZ′ = 2, and in one of the two independent molecular types the cyclohexylamine unit is disordered over two sets of atomic sites

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10

Krishna Prasad, Ch, and P. V. S. Machiraju. "Synthesis and characterization of some novel aryl and heteroaryl chalcone derivatives of 3-(3,4,5-trimethoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde for assessing their potentials as anticancer agents." Russian Journal of General Chemistry 87, no. 9 (2017): 2056–66. http://dx.doi.org/10.1134/s1070363217090225.

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