Academic literature on the topic '3-b] quinolines'

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Journal articles on the topic "3-b] quinolines"

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Sonawane, Amol D., Dinesh R. Garud, Taro Udagawa, and Mamoru Koketsu. "Synthesis of thieno[2,3-b]quinoline and selenopheno[2,3-b]quinoline derivativesviaiodocyclization reaction and a DFT mechanistic study." Organic & Biomolecular Chemistry 16, no. 2 (2018): 245–55. http://dx.doi.org/10.1039/c7ob02523h.

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Thieno[2,3-b]quinoline and selenopheno[2,3-b]quinoline derivatives were synthesized by the regioselective iodocyclization reaction of 3-alkynyl-2-(methylthio)quinolines and 3-alkynyl-2-(methylseleno)quinolines.
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Xie, Jian-Wu, Jia-Wen Zhang, Li-Si-Han Yu, Jian-Lian Dong, and Qi-Chao Sun. "Enantioselective Construction and Transformations of Poly­functionalized 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines." Synlett 29, no. 05 (2017): 603–8. http://dx.doi.org/10.1055/s-0036-1591838.

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We developed an enantioselective organocascade Michael/Henry reaction in the presence of a bifunctional organocatalyst to construct chiral polyfunctionalized 3,4-dihydro-2H-thiopyrano[2,3-b]quinolines. The resulting optically active products with three contiguous stereocenters, one quaternary and two tertiary, were obtained in moderate to good yields and with good to excellent enantioselectivities. Remarkably, the resulting products were readily converted into polyfunctionalized optically active furo[2′,3′:4,5]thiopyrano[2,3-b]quinoline, 3,4-dihydro-2H-thiopyrano[2,3-b]quinoline 1-oxide and 2,
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Portilla, Jaime, Jairo Quiroga, Manuel Nogueras, et al. "Structural comparisons of isomeric series of 7-aryl-benzo[h]pyrazolo[3,4-b]quinolines and 11-aryl-benzo[f]pyrazolo[3,4-b]quinolines." Acta Crystallographica Section B Structural Science 64, no. 1 (2008): 72–83. http://dx.doi.org/10.1107/s0108768107065743.

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The structures of three new 7-aryl-benzo[h]pyrazolo[3,4-b]quinolines, 8-methyl-7-(4-chlorophenyl)-10-phenyl-6,10-dihydro-5H-benzo[h]pyrazolo[3,4-b]quinoline, C27H20ClN3, 8-methyl-7-(3-pyridinyl)-10-phenyl-6,10-dihydro-5H-benzo[b]pyrazolo[3,4-b]quinoline, C26H20N4, and 8-methyl-7-(4-pyridinyl)-10-phenyl-10H-benzo[h]pyrazolo[3,4-b]quinoline, C26H18N4, which is an unexpected oxidation product isolated from the attempted synthesis of 8-methyl-7-(4-pyridinyl)-10-phenyl-6,10-dihydro-5H-benzo[h]pyrazolo[3,4-b]quinoline, and those of three new 11-aryl-benzo[f]pyrazolo[3,4-b]quinolines, 11-(4-methylphe
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Abd El-Aal, Hassan A. K., and Talaat I. El-Emary. "Synthesis of Tetracyclic Fused Quinolines via a Friedel–Crafts and Beckmann Ring Expansion Sequence." Australian Journal of Chemistry 72, no. 12 (2019): 945. http://dx.doi.org/10.1071/ch19363.

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An efficient protocol for the construction of tetracyclic fused quinolines (pyrazole-fused azepino-, azocino-, and azonino[3,2-b]quinolinones) via consecutive Friedel–Crafts and Beckmann reactions has been developed. The key steps in the syntheses of these new molecular scaffolds involve acid-mediated cyclization of 2-(pyrazol-3-yl)quinoline based carboxylic acids 6a–c, 8, and 12 to ketones 13a–e, followed by Beckmann rearrangements of the corresponding oximes 14a–e to provide the tetracyclic-fused quinoline skeletons 15a–e. Structures of synthesised compounds without stereochemical implicatio
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Abd El-Aal, Hassan A. K., and Talaat I. El-Emary. "Corrigendum to: Synthesis of Tetracyclic Fused Quinolines via a Friedel–Crafts and Beckmann Ring Expansion Sequence." Australian Journal of Chemistry 72, no. 12 (2019): 990. http://dx.doi.org/10.1071/ch19363_co.

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An efficient protocol for the construction of tetracyclic fused quinolines (pyrazole-fused azepino-, azocino-, and azonino[3,2-b]quinolinones) via consecutive Friedel–Crafts and Beckmann reactions has been developed. The key steps in the syntheses of these new molecular scaffolds involve acid-mediated cyclization of 2-(pyrazol-3-yl)quinoline based carboxylic acids 6a–c, 8, and 12 to ketones 13a–e, followed by Beckmann rearrangements of the corresponding oximes 14a–e to provide the tetracyclic-fused quinoline skeletons 15a–e. Structures of synthesised compounds without stereochemical implicatio
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Wang, Cunde, Xushun Qing, Ting Wang, Chenlu Dai, and Zhenjie Su. "Direct Synthesis of 6H-Chromeno[3,4-b]quinolin-6-ol Derivatives from Substituted 3-Nitro-2H-chromenes and 2-Nitrobenzaldehydes Mediated by Fe/AcOH System." Synthesis 50, no. 06 (2017): 1350–58. http://dx.doi.org/10.1055/s-0036-1589154.

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An efficient iron/acetic acid system-mediated reductive cyclization reaction of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes for the synthesis of 6-aryl-6H-chromeno[3,4-b]quinolines was developed. This reaction involves the sequential reduction, hydrolysis, aldol condensation, intramolecular addition, and the nucleophilic addition of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes to give the corresponding 6H-chromeno[3,4-b]quinolines. This transformation provides a straightforward synthetic protocol for constructing substituted 6H
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Bakhite, Etify Abdel-Ghafar. "Synthesis and Reactions of Some New 3-Amino-2-substituted Thieno[2,3-b]quinolines." Collection of Czechoslovak Chemical Communications 57, no. 11 (1992): 2359–66. http://dx.doi.org/10.1135/cccc19922359.

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Reaction of 3-cyano-quinolin-2(1H)-thione (II) with ω-bromoacetophenones gave 3-amino-2-aroyl-thieno[2,3-b]quinolines (IVa-IVd). Whereas, interaction of II with chloroacetanilides yielded the corresponding thioesters Va-Vc which cyclized into 3-amino-2-arylcarbamoylthiene[2,3-b]quinolines (VIa-VIc) on treatment with ethoxide. Compounds VIa-VIc were reacted with nitrous acid, triethyl orthoformate and carbon disulfide to afford the fused polycyclic compounds VIIa-VIIc, VIIIa-VIIIc and IXa-IXc, respectively. Also treatment of IXa-IXc with ethyl iodide gave 3-ethylthio derivatives Xa-Xc. Moreover
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Shiri, Morteza, Maryam-Sadat Tonekaboni, Zahra Tanbakouchian, and Soma Majedi. "Synthesis of [1,4]Oxathiepino[5,6-b]quinolines via Base-Mediated Intramolecular Hydroalkoxylation." SynOpen 06, no. 01 (2022): 7–10. http://dx.doi.org/10.1055/s-0040-1719868.

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AbstractA base-mediated intramolecular hydroalkoxylation that was used to prepare a series of seven-membered S,O-heterocycles is described. 2-Thiopropargyl-3-hydroxymethyl quinolines were prepared starting from 2-mercaptoquinoline-3-carbaldehydes, via S-propargylation and reduction of a formyl group. Interestingly, 2-mercaptopropargyl-3-hydroxymethyl quinolines were converted into the corresponding oxathiepinoquinolines in the presence of t-BuOK. It is proposed that the S-propargyl moiety, in the presence of base, is converted into its allenyl isomer; subsequent addition of a hydroxyl group to
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Morteza, Shiri, Fathollahi-Lahroud Mina, and Yasaei Zahra. "A novel strategy for the synthesis of 6H-chromeno [4, 3-b] quinoline by intramolecular Heck cyclization." Tetrahedron 73, no. 17 (2017): 2501–3. https://doi.org/10.1016/j.tet.2017.03.043.

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A novel procedure for the synthesis of various derivatives of 6H-chromeno [4, 3-b] quinolines from intramolecular Heck reaction of 2-chloro-3-(phenoxymethyl) quinolines is described in this study. Intramolecular cyclization of N-alkylated indoles was efficiently investigated as well. The reaction is catalyzed by bis (triphenylphosphine) palladium (II) dichloride in acetonitrile at 80 °C.
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Wojciechowski, Krzysztof, and Michał Nowacki. "Synthesis of [1]Benzothieno[2,3-b]quinolines via Transition-Metal-Free [3+3] Annulation of Nitroarenes and Benzo[b]thiophen-3-ylacetonitrile or 3-(Phenylsulfonylmethyl)benzo[b]thiophene Carbanions." Synthesis 49, no. 16 (2017): 3794–800. http://dx.doi.org/10.1055/s-0036-1588426.

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Benzo[b]thiophen-3-ylacetonitriles or 3-(phenylsulfonylmethyl)benzo[b]thiophenes react with nitrobenzene derivatives in the presence of potassium tert-butoxide and chlorotrimethylsilane to form, in good yields, 11-cyano- or 11-(phenylsulfonyl)[1]benzothieno[2,3-b]quinolines, respectively.
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Dissertations / Theses on the topic "3-b] quinolines"

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Yougnia, Rodrigue. "Conception, synthèse et évaluation biologique de nouveaux ligands alkylants de l'ADN à visée anticancéreuse en séries pyrano[2',3':7,8]quino[2,3-b]quinoxalin-12(5H)-one et pyrano[2,3-h]pyrazino[2,3-b]quinolin-10(5h)-one." Paris 5, 2007. http://www.theses.fr/2007PA05P615.

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L’objet de ce travail est l’obtention d’aza-analogues de séries acronycine ou benzo[b]acronycine. Ces composés présentent deux azotes en para introduits soit sur le cycle A de l’acronycine ou sur le cycle B de la benzo[b]acronycine. Une série pyrano[2’,3’:7,8]quino[2,3-b]quinoxalin-12(5H)-one et une série pyrano[2,3-h]pyrazino[2,3-b]quinolin-10(5H)-one ont ainsi été préparées. L’activité cytotoxique, in vitro des différents composés ainsi préparés a été évaluée sur cellules leucémiques murines L1210 et tumeur solide humaine (carcinome épidermoïde buccal KB-3-1). Certains composés se sont révél
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Lin, Chan-Chieh, and 林占杰. "Efficient and Cost-Effective Protocols for the Synthesis of Hexahydrocyclohepta[b]indoles and 4-(1H-indol-3-yl)quinolines." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/90358957801825450613.

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碩士<br>國立臺灣師範大學<br>化學系<br>99<br>This thesis is divided into two parts. The first part of this thesis described an expedient protocol for the synthesis of hexahydrocyclohepta[b]indole derivatives via double Michael addition by using inexpensive and commercially available N-bromosuccinimide (NBS) and iodine as catalysts. NBS catalyzed the Michael addition of indole and the step of cyclization was catalyzed by iodine. Hexahydrocyclohepta[b]indole derivatives are important as they possess great biological and pharmacological activities. The second part of the thesis deals with a facile route for t
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Tseng, Ruoh-Tyng, and 曾若婷. "Synthesis and Biological Activity of N-substituted benzyl-6( or 7 )-chloro-2, 3, 4, 9-tetrahydrofuro[2,3-b]quinolin-3,4-diones and Related Compounds." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/53299819664445081338.

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碩士<br>中國醫藥學院<br>藥物化學研究所<br>87<br>A series of N-substituted benzyl-6( or 7 )-chloro-2, 3, 4, 9-tetrahydrofuro[2,3-b]quinolin-3,4-diones and related compounds has been synthesized and assigned by their spectra data. All of these synthetic compounds were evaluated for antiallergic and antiinflammatory activity by inhibition tests of mast cell degranulation, neutrophil degranulation , and neutrophil superoxide formation. Among these tested results, Np-chlorobenzyl-7-chloro-2,3,4,9-tetrahydrofuro[2,3-b]quinolin-3,4-dione (14) exhibited inhibitory activity on fMLP-induced neutrophil degr
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Book chapters on the topic "3-b] quinolines"

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Yokoshima, Satoshi. "Construction of Quinoline N-Oxides and Synthesis of Aurachins A and B: Discovery, Application, and Mechanistic Insight." In Modern Natural Product Synthesis. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1619-7_17.

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AbstractA method to synthesize 3-hydroxyquinoline N-oxides from ketones having a 2-nitrophenyl group at the α-position relative to the carbonyl group was developed. The substrates were easily prepared via a SNAr reaction or a Sonogashira coupling, and treatment with sodium tert-butoxide in dimethyl sulfoxide produced the corresponding quinoline N-oxides. The method was successfully applied to the total synthesis of aurachins A and B. On the basis of the quinoline N-oxide synthesis, related reactions of α-(2-nitrophenyl)ketones, including nitrone formation and photoinduced rearrangement, were a
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Nandeshwarappa, B. P., G. K. Prakash, and S. O. Sadashiv. "Introductory Chapter: Synthesis and Antimicrobial Activities of Dihydroazeto[2′,3′:4,5]seleno[2,3-b]quinolines." In Heterocycles - Synthesis and Biological Activities. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92030.

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Harris, P. A. "10.24.1 Product Subclass 1: Pyrido[1,2-a]indoles and Related Benzo-Fused Ring Systems." In Science of Synthesis: Knowledge Updates 2021/3. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/sos-sd-110-01870.

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AbstractThis review describes methods for the synthesis of pyrido[1,2-a]indoles, as well as the related benzo-fused ring systems indolo[1,2-a]quinolines, indolo[1,2-b]isoquinolines, indolo[2,1-a]isoquinolines, and indolo[1,2-f]phenanthridines. The most common routes to access these ring systems involve a variety of transition-metal-catalyzed cyclizations, but alternative approaches are also covered.
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"7,12-Dihydronaphtho[2′,3′:4,5]furo[2,3-f]quinoline (21) to 7,8-Dihydronaphtho[1′,8′:5,6,7]oxepino[3,2-b]indole (21)." In Substance index, edited by Backes, Fröhlich, and Padeken. Georg Thieme Verlag, 2002. http://dx.doi.org/10.1055/b-0035-114925.

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Conference papers on the topic "3-b] quinolines"

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Manabe, S., H. Yanagisawa, S. Ishikawa, et al. "TRYPTOPHAN PYROLYSIS PRODUCTS FOUND IN COOKED FOODS INHIBIT HUMAN PLATELET AGGREGATION BY INHIBITING CYCLOOXYGENASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643402.

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Humans are exposed to numerous toxic compounds in foods. During the past decade, several carcinogenic heterocyclic amines have been reported to be present in the cooked foods. Recently, we reported that some of the carcinogenic heterocyclic amines isolated from foods were present in human plasma. In order to know the effects of the carcinogens isolated from foods on the cell function, we investigated the effects of the carcinogenic heterocyclic amines including Trp-P-1(3-amino-l,4-dimethyl-5H-pyrido❘4,3-b❘indole) and Trp-P-2(3-amino-1-methyl-5H-pyrido❘4,3-b❘indole) on human platelet aggregatio
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