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Journal articles on the topic '3-Benzazepinones'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Zhang, Lei, Deju Ye, Yu Zhou, et al. "Regioselective Synthesis of 3-Benzazepinones and Unexpected 5-Bromo-3-benzazepinones." Journal of Organic Chemistry 75, no. 11 (2010): 3671–77. http://dx.doi.org/10.1021/jo100378u.

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2

Zhang, Lei, Deju Ye, Yu Zhou, et al. "ChemInform Abstract: Regioselective Synthesis of 3-Benzazepinones and Unexpected 5-Bromo-3-benzazepinones." ChemInform 41, no. 41 (2010): no. http://dx.doi.org/10.1002/chin.201041171.

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3

Thimmaiah, Shubhavathi, Mallesha Ningegowda, Nanjunda Swamy Shivananju, Raghu Ningegowda, Ranjith Siddaraj, and Babu Shubha Priya. "Eaton’s reagent catalysed alacritous synthesis of 3-benzazepinones." European Journal of Chemistry 7, no. 4 (2016): 391–96. http://dx.doi.org/10.5155/eurjchem.7.4.391-396.1477.

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4

Mitchell, D., Y. Yu, and G. Stephenson. "Synthesis of 3-Benzazepinones via Palladium-Catalyzed Hydroamination." Synfacts 2006, no. 8 (2006): 0766. http://dx.doi.org/10.1055/s-2006-941972.

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5

Xie, Xiaozhou, and Jiangtao Sun. "[4+3]-Cycloaddition Reaction of Sulfilimines with Cyclobutenones: Access to Benzazepinones." Organic Letters 23, no. 22 (2021): 8921–25. http://dx.doi.org/10.1021/acs.orglett.1c03413.

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6

Yu, Ying, Gregory A. Stephenson, and David Mitchell. "A regioselective synthesis of 3-benzazepinones via intramolecular hydroamidation of acetylenes." Tetrahedron Letters 47, no. 23 (2006): 3811–14. http://dx.doi.org/10.1016/j.tetlet.2006.03.198.

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7

T., Shubhavathi1 Raghu Ram Achar2 B.S. Priya1*. "3-BENZAZEPINONE DERIVATIVES: ANTIOXIDANT ACTIVITY AND ITS STRUCTURE ACTIVITY RELATIONSHIP (SAR) STUDIES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7415–19. https://doi.org/10.5281/zenodo.1006933.

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A series of 3-benzazepinone (3-BZ) derivatives were tested for their in vitro antioxidant efficacy by DPPH and LPO assays and compared with standard Butylated Hydroxyl Anisole (BHA). The derivatives containing electron donating groups viz., OH, OCH3 were found to be good antioxidants compared to BHA. While, the compounds containing electron withdrawing moiety viz., NO2, Cl, Br, and F were found to be less active compared to standard BHA. The structure activity relationship studies suggest that the electron donating moieties majorly contribute to the anti-oxidant property of the potent compound
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8

Frutos-Pedreño, Roberto, Eva García-Sánchez, María José Oliva-Madrid, et al. "C–H Activation in Primary 3-Phenylpropylamines: Synthesis of Seven-Membered Palladacycles through Orthometalation. Stoichiometric Preparation of Benzazepinones and Catalytic Synthesis of Ureas." Inorganic Chemistry 55, no. 11 (2016): 5520–33. http://dx.doi.org/10.1021/acs.inorgchem.6b00542.

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9

Anand, Aditi, Navjeet Kaur, and Dharma Kishore. "An Efficient One Pot Protocol to the Annulation of Face “d” of Benzazepinone Ring with Pyrazole, Isoxazole, and Pyrimidine Nucleus through the Corresponding Oxoketene Dithioacetal Derivative." Advances in Chemistry 2014 (August 6, 2014): 1–5. http://dx.doi.org/10.1155/2014/358153.

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A highly facile single step approach to the annulation of face “d” of benzazepinone nucleus with pyrazole, isoxazole, and pyrimidine ring has been described. The annulation proceeded smoothly on the reaction of oxoketene dithioacetal derivative 3 with (i) NH2–NH2·H2O, (ii) NH2OH·HCl, (iii) acetamidine hydrochloride, (iv) guanidine nitrate, (v) urea, and (vi) thiourea which yielded the pyrazolo, isoxazolo, and pyrimido annulated analogues of benzazepinone 4–9, respectively, in acceptable yields. The 4-ketene dithioacetal analogue of 7-fluorobenzo[b]azepine-2,5-dione (3) was in turn obtained fro
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10

Floyd, David M., Robert V. Moquin, Karnail S. Atwal, et al. "Synthesis of benzazepinone and 3-methylbenzothiazepinone analogs of diltiazem." Journal of Organic Chemistry 55, no. 21 (1990): 5572–79. http://dx.doi.org/10.1021/jo00308a013.

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11

Schoen, William R., Judith M. Pisano, Kristine Prendergast, et al. "A Novel 3-Substituted Benzazepinone Growth Hormone Secretagogue (L-692,429)." Journal of Medicinal Chemistry 37, no. 7 (1994): 897–906. http://dx.doi.org/10.1021/jm00033a006.

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12

Das, Jagabandhu, David M. Floyd, S. David Kimball, et al. "Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones." Journal of Medicinal Chemistry 35, no. 4 (1992): 773–80. http://dx.doi.org/10.1021/jm00082a019.

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13

FLOYD, D. M., R. V. MOQUIN, K. S. ATWAL, et al. "ChemInform Abstract: Synthesis of Benzazepinone and 3-Methylbenzothiazepinone Analogues of Diltiazem." ChemInform 22, no. 7 (2010): no. http://dx.doi.org/10.1002/chin.199107169.

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14

Husain, Syed Masood, Roland Fröhlich, Dirk Schepmann, and Bernhard Wünsch. "Enantioselective Synthesis of a 2,2-Disubstituted Tetrahydro-3- benzazepine as Novel NMDA Receptor Antagonist." Zeitschrift für Naturforschung B 65, no. 2 (2010): 191–96. http://dx.doi.org/10.1515/znb-2010-0216.

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The tricyclic oxazolidines trans-4 and cis-4 were interconverted upon treatment with allyltrimethylsilane/ TiCl4. The oxazolidine trans-4 was diastereoselectively reacted with PhMgBr to yield the 4,4-disubstituted 3-benzazepinone 6, along with two side products. An X-ray crystal structure analysis of 6 proved the (R)-configuration of the stereogenic center C-4 and thus the retention of configuration. Reduction of 6 with AlCl3/LiAlH4 (1/3) followed by hydrogenolysis with H2, Pd/C resulted in the formation of enantiomerically pure 2-methyl-2-phenyl-tetrahydro-3-benzazepine 11 which has a moderat
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15

SCHOEN, W. R., J. M. PISANO, K. PRENDERGAST, et al. "ChemInform Abstract: A Novel 3-Substituted Benzazepinone Growth Hormone Secretagogue (L-692, 429) (IX)." ChemInform 25, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.199434184.

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16

Yu, Ying, Gregory A. Stephenson, and David Mitchell. "A Regioselective Synthesis of 3-Benzazepinones via Intramolecular Hydroamidation of Acetylenes." ChemInform 37, no. 37 (2006). http://dx.doi.org/10.1002/chin.200637140.

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17

T., Shubhavathi1 Raghu Ram Achar2 B.S. Priya1*. "3-BENZAZEPINONE DERIVATIVES: ANTIOXIDANT ACTIVITY AND ITS STRUCTURE ACTIVITY RELATIONSHIP (SAR) STUDIES." January 31, 2017. https://doi.org/10.5281/zenodo.2381685.

Full text
Abstract:
A series of 3-benzazepinone (3-BZ) derivatives were tested for their in vitro antioxidant efficacy by DPPH and LPO assays and compared with standard Butylated Hydroxyl Anisole (BHA). The derivatives containing electron donating groups viz., OH, OCH3 were found to be good antioxidants compared to BHA. While, the compounds containing electron withdrawing moiety viz., NO2, Cl, Br, and F were found to be less active compared to standard BHA. The structure activity relationship studies suggest that the electron donating moieties majorly contribute to the anti-oxidant property of the potent compound
APA, Harvard, Vancouver, ISO, and other styles
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