Academic literature on the topic '3-oxadiazol'

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Journal articles on the topic "3-oxadiazol"

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Stepanova, Elena V., and Andrei I. Stepanov. "UNUSUAL WAY OF REACTION OF 3-AMINO-4-(5-CHLOROMETHYL-1,2,4-OXADIAZOLE-3-YL)-FURAZAN WITH HYDRAZINE." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 4 (2017): 26. http://dx.doi.org/10.6060/tcct.2017604.5522.

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The results of our study of the pathways of selective reactivity of 3-amino-4-(5-chloromethyl-1,2,4-oxadiazole-3-yl)furazan versus 5-unsubstituted or 5-methyl and 5-trifluoromethyl substituted 4-(5R-1,2,4-oxadiazole-3-yl)furazans (R = H, Me, CF3) towards the action of hydrazine are discussed. If the reductive opening of 1,2,4-oxadiazole ring in unsubstituted at the С-5 atom (1,2,4-oxadiazol-3-yl)furazan derivatives under the treatment with hydrazine can be used as a method for the preparation of a range of amidrazones of 4-R-furazan-3-carboxylic acid. 3-amino-4-(5-trifluoromethyl-1,2,4-oxadiaz
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Tang, Yongxing, Chunlin He, Lauren A. Mitchell, Damon A. Parrish, and Jean'ne M. Shreeve. "Energetic compounds consisting of 1,2,5- and 1,3,4-oxadiazole rings." Journal of Materials Chemistry A 3, no. 46 (2015): 23143–48. http://dx.doi.org/10.1039/c5ta06898c.

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3-Nitroamino-4-(5-amino-1,3,4-oxadiazol-2-yl)furazan monohydrate (2·H<sub>2</sub>O), which is a combination of the nitroaminofurazan and 1,3,4-oxadiazole rings, was obtained by the nitration of 3-amino-4-(5-amino-1,3,4-oxadiazol-2-yl)furazan (1) with 100% nitric acid.
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Pagoria, Philip, Maoxi Zhang, Ana Racoveanu, Alan DeHope, Roman Tsyshevsky, and Maija Kuklja. "3-(4-Amino-1,2,5-oxadiazol-3-yl)-4-(4-nitro-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazole." Molbank 2014, no. 2 (2014): M824. http://dx.doi.org/10.3390/m824.

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Saini, Sachin. "Synthesis and Anticonvulsant Studies of Thiazolidinone and Azetidinone Derivatives from Indole Moiety." Drug Research 69, no. 08 (2018): 445–50. http://dx.doi.org/10.1055/a-0809-5098.

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Abstract2-Amino-5-(3’-indolomethylene)-1, 3 , 4 - oxadiazole (3) undergoes facile condensation with various aromatic aldehydes to gave 2-substitiuted arylidenylamino-5-(3’- indolomethylene) – 1, 3 , 4 – oxadiazole (4–8). Cyclocondensation of (4–8) with thioglycolic acid and triethylamine yielded 3-[5’-(3”- indolomethylene)- 1’, 3’, 4’- oxadiazol-2’-yl]- 2- (substituted aryl)-4- thiazolidinones (9–13) and 1-[5’-(3”- indolomethylene) -1’, 3’, 4’- oxadiazol - 2’- yl ] -4-(substituted aryl) -2- azetidinones (14–18). The structures of these compounds were established on the basis of analytical and
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Maftei, Catalin V., Elena Fodor, Peter G. Jones, et al. "Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties." Beilstein Journal of Organic Chemistry 9 (October 25, 2013): 2202–15. http://dx.doi.org/10.3762/bjoc.9.259.

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Taking into consideration the biological activity of the only natural products containing a 1,2,4-oxadiazole ring in their structure (quisqualic acid and phidianidines A and B), the natural product analogs 1-(4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)phenyl)pyrrolidine-2,5-dione (4) and 1-(4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)phenyl)-1H-pyrrole-2,5-dione (7) were synthesized starting from 4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)aniline (1) in two steps by isolating the intermediates 4-(4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)phenylamino)-4-oxobutanoic acid (3) and (Z)-4-(4-(3-tert-butyl-1,2,4-oxadiazol-5
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Jia, Si-Yuan, Bo-Zhou Wang, Xue-Zhong Fan, Ping Li, and Seik Weng Ng. "4-[4-(4-Amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine." Acta Crystallographica Section E Structure Reports Online 68, no. 5 (2012): o1573. http://dx.doi.org/10.1107/s1600536812017825.

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Xiong, Hualin, Hongwei Yang, Caijin Lei, Pengjiu Yang, Wei Hu, and Guangbin Cheng. "Combinations of furoxan and 1,2,4-oxadiazole for the generation of high performance energetic materials." Dalton Transactions 48, no. 39 (2019): 14705–11. http://dx.doi.org/10.1039/c9dt02684c.

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Energetic materials, comprising furoxan and 1,2,4-oxadiazole backbones, were synthesized by nitrating 3,3′-bis(5-amino-1,2,4-oxadiazol-3-yl)-4,4′-azofuroxan, followed by cation metathesis, giving compounds with high density, high detonation performance and acceptable sensitivities.
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Tkachuk, V., T. Lyubchuk, T. Tkachuk, and O. Hordiyenko. "A DEVELOPMENT OF AN EFFECTIVE METHOD FOR THE SYNTHESIS OF 2-(5-OXO-4,5-DIHYDRO-1,2,4-OXADIAZOL-3-YL)BENZOIC ACID." Bulletin of Taras Shevchenko National University of Kyiv. Chemistry, no. 1 (57) (2020): 51–54. http://dx.doi.org/10.17721/1728-2209.2020.1(57).13.

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2-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzoic acid was synthesized using a new effective method – thermal heterocyclization of 3-(hydroxyimino)isoindolin-1-one, which occurs as a result of its interaction with 1,1'-carbonyldiimidazole (CDI) and subsequent base-promoted cycleopening of the obtained intermediate 3H,5H-[1,2,4]oxadiazolo[3,4-a]isoindole-3,5-dione. Direct cyclization of 3-(hydroxyimino)isoindolin-1-one by the reaction with diethyl carbonate in the presence of sodium ethylate in ethanol at room temperature and under heating was unsuccessful. The same result was observed when usi
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Wu, Xiang-Wen, Meng-Meng Xin, Jian-Ping Ma, Zhen-Hua Wu, and Yu-Bin Dong. "The coordination chemistry of two symmetric double-armed oxadiazole-bridged organic ligands with copper salts." Acta Crystallographica Section C Crystal Structure Communications 69, no. 6 (2013): 601–5. http://dx.doi.org/10.1107/s0108270113010913.

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Two new symmetric double-armed oxadiazole-bridged ligands, 4-methyl-{5-[5-methyl-2-(pyridin-3-ylcarbonyloxy)phenyl]-1,3,4-oxadiazol-2-yl}phenyl pyridine-3-carboxylate (L1) and 4-methyl-{5-[5-methyl-2-(pyridin-4-ylcarbonyloxy)phenyl]-1,3,4-oxadiazol-2-yl}phenyl pyridine-4-carboxylate (L2), were prepared by the reaction of 2,5-bis(2-hydroxy-5-methylphenyl)-1,3,4-oxadiazole with nicotinoyl chloride and isonicotinoyl chloride, respectively. LigandL1 can be used as an organic clip to bind CuIIcations and generate a molecular complex, bis(4-methyl-{5-[5-methyl-2-(pyridin-3-ylcarbonyloxy)phenyl]-1,3,
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Jin, Guoxia, Yuqi Ji, Teng Wang, et al. "Syntheses and characterization of dinuclear and tetranuclear AgI supramolecular complexes generated from symmetric and asymmetric molecular clips containing oxadiazole rings." Acta Crystallographica Section C Structural Chemistry 75, no. 10 (2019): 1327–35. http://dx.doi.org/10.1107/s2053229619011744.

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A new asymmetric ligand, 5-{3-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}-2-(pyridin-3-yl)-1,3,4-oxadiazole (L5), which contains two oxadiazole rings, was synthesized and characterized. The assembly of symmetric 2,5-bis(pyridin-3-yl)-1,3,4-oxadiazole (L1) and asymmetric L5 with AgCO2CF3 in solution yielded two novel AgI complexes, namely catena-poly[[di-μ-trifluoroacetato-disilver(I)]-bis[μ-2,5-bis(pyridin-3-yl)-1,3,4-oxadiazole]], [Ag2(C2F3O2)2(C12H8N4O)2] n or [Ag2(μ2-O2CCF3)2(L1)2] n (1), and bis(μ3-5-{3-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}-2-(pyridin-3-yl)-1,3,4-oxadiazole
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Dissertations / Theses on the topic "3-oxadiazol"

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Conde, Amanda Solis. "Synthesis of 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one derivatives by electrophilic aromatic substitution." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1547584724393162.

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Bhat, Shreesha V. "Synthesis of 1,2,4 oxadiazol-5-imine, 1,2,4-triazol-3-imine and derivatives : a substituted cyanamide-based strategy for heterocycle synthesis." Thesis, University of Lincoln, 2017. http://eprints.lincoln.ac.uk/28632/.

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Considering the importance of nitrogen-rich heterocycles in drug discovery, a novel strategy towards heterocycle synthesis was envisioned using cyanamide chemistry. Synthesis which involve mild conditions, avoids multi-step sequence and non-toxic reagents are desirable for generation of large combinatorial libraries of drug molecules. We envisaged that the NCN linkage of the cyanamide as well as the concomitant use of the nucleo-and electrophilic centres of the cyanamide could provide a novel synthetic route towards nitrogen heterocycles. The first part (Ch-2) constitute the bulk of the thesis
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Almeida, Leonardo Viana de. "Síntese e determinação da atividade antimicrobiana de 2-[5-nitro-tiofen-2-il]-3-acetil-5-[4-fenil-substituído]-2,3-diidro-1,3,4-oxadiazol frente à cepa ATCC 25923 de Staphylococcus aureus." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9135/tde-07042010-131506/.

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A introdução de um grupo substituinte na molécula de um fármaco promove alterações químico-estruturais que, por sua vez, modificam suas propriedades físicoquímicas. O arranjo espacial de átomos ou grupos de átomos, em especial grupos funcionais, na molécula de um fármaco, expressos por meio de suas propriedades físico-químicas, influenciam direta ou indiretamente na interação fármaco-receptor. Esta, por sua vez, determina aspectos farmacológicos e farmacocinéticos que influem na eficácia terapêutica do medicamento. Assim, uma série de compostos 2-[5-nitro-tiofen-2-il]-3-acetil-5-[4-fenil-subst
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Wolf, Lucas. "Síntese de heterociclos: 2-alquil/arilcalcogeno-n-(4-aril-1,3-tiazol-2-il)acetamidas e (s)-n-(1-(3-aril-1,2,4-oxadiazol-5-il)alquil)-2-(calcogenofenil) acetamidas derivados de organocalcogênios." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/4271.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>In the present work, a series of 2-alkyl/arylchalcogenide-N-(4-aryl-1,3-thiazol-2-yl)acetamide was prepared via addition of aryl or alkyl chalcogenides. This methodology allowed the preparation of new derivatives of 2-amino-1,3-thiazoles in good yields. The compound synthesized is intended to evaluate the biological potential from the antioxidant activity by scavenging capacity of the assay by ABTS and DPPH. Was also developed a methodology for obtaining the compounds (S)-N-(alkyl-1-(3-aryl-1,2,4-oxadiazol-5-yl)-2-(phenylchalcogeni
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Pisarenko, Irina [Verfasser], та Joachim Kurt [Akademischer Betreuer] Fandrey. "Interaktionsanalyse der Hypoxie-induzierbaren Transkriptionsfaktoren HIF-2α und ARNT unter Berücksichtigung der Einflussnahme durch den HIF-2α-Liganden N-(3-Chloro-5-fluorophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine und verschiedener HIF-2α-Mutationen / Irina Pisarenko ; Betreuer: Joachim Kurt Fandrey". Duisburg, 2018. http://d-nb.info/1159879133/34.

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Singh, Neeraj. "Generation of 4,5-Dihydro-1,2,3-oxadiazole and Study of the Decomposition Products." Doctoral thesis, Universitätsbibliothek Chemnitz, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-191706.

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4,5-Dihydro-1,2,3-oxadiazoles are postulated to be key intermediates in the synthesis of ketones from alkenes on an industrial scale, alkylation of DNA in vivo, decomposition of N-nitrosoureas (potent carcinogens), and are also a subject of great interest for theoretical chemists. In this thesis, formation of the parent compound and decay into secondary products has been studied by NMR monitoring analysis. The elusive properties and the intermediacy of the parent compound, 4,5-dihydro-1,2,3-oxadiazole, in the decomposition of suitably substituted N-nitrosoureas using Tl(I) alkoxides as bases,
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廖英舜. "Design, Synthesis and Biological Evaluation of 5-(1,2,4-Oxadiazol-3-yl)uridine Derivatives." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/10302593033360195001.

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碩士<br>國立臺灣師範大學<br>化學系<br>98<br>TMPKmt (thymidine monophosphate kinase of Mycobacterium tuberculosis) catalyzes the conversion of thymidine to TMP (thymidine monophosphate). TMP is an important component for DNA replication. According to the affinity between TMPKmt for the TMP analogues, we interpreted that there could be a binding pocket in TMPKmt around the 5-substituent on thymidine. Therefore, 5-substituted uridine derivatives could be potential agents possessing antiviral and anticancer activities. Synthesis of 5-(5-substituted-1,2,4-oxadiazole)uridine was accomplished starting from 5-cyan
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林建邦. "Design, Synthesis and Biological Evaluation of 6-Alkylaminouridine and 6-(1,2,4-Oxadiazol-3-yl)uridine Derivatives." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/44401069178815271331.

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碩士<br>國立臺灣師範大學<br>化學系<br>98<br>The focus of this thesis is the synthesis of derivatives for 6-aminouridine and 6-(1,2,4-oxadiazol-3-yl)uridine as a potential inhibitors for orotidine 5’-monophosphate decarboxylase (ODCase). The 6-Cyano-1,3-dimethyluracil was chosen as the reaction model to investigate the substitution reaction with alkylamines as underwent nucleophiles. Our studies have shown that 6-cyano-1,3-dimethyluracil substitution reaction only with primary amines with primary alkyl substitutes. Finally, the reaction was applied for the synthesis of several 6-alkylaminouridine deriv
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Li, Ing-Ju, and 李盈儒. "Studies on the Synthesis and Light-Emitting Properties of 9-Substituted-3-(5-aryl-[1,3,4]oxadiazol-2-yl)-9H-carbazole." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/32977857187737798000.

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碩士<br>國立成功大學<br>化學系碩博士班<br>91<br>In this thesis the luminescent organic material was synthesized using carbazole as a starting material and KMnO4 as a cyclization reagent. The structure, physical and electroluminiecent properties for the obtained products including carbazole series and their indole derivatives were studied by the analysis of NMR elemental analysis IR, DSC,TGA,UV-VIS,CV,PL spectrum and EL test. For the thermal stability , all synthesized compounds had good thermal decomposition temperatures ,but low glass transition temperatures. The result for PL spectrum analysis indicat
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Wang, Ying Shuo, and 王膺碩. "Synthesis and properties of discotic liquid crystalline crystals based on the disk-like mesogenic groups of 1,3,5-tris(5-phenyl-1,3,4-oxadiazol-2-yl)benzene, dibebzo[2,3-a:2',3'-c]phenazine, and diphenanthro[b:i]-1,4,6,9-tetraazaanthracene." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/06925076558685435859.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>89<br>Three series of discotic liquid crystals with alkyl side chain from 3~12 carbon atoms were prepared and characterized. In the series Ⅰ, three types of discotic liquid crystals with changing the number of flexible long alkyl chains in the surroundings of a 1,3,5-tris(5-phenyl) -1,3,4-oxadiazol-2-yl)benzene core were synthesized: 1,3,5-tris[5-(3,4,5-trialkoxy phenyl)-1,3,5-oxadiazol-2-yl]benzene,TPOB3-n(n=3~12)(R1=R2=R3=OCnH2n+1) (Scheme Ⅰ). 1,3,5-Tris[5-(3,4-dialkoxyphenyl)-1,3,5-oxadiazol-2-yl]benzene, TPOB2-n(n=3~12)(R1=R2=OCnH2n+1 and R3=H)(Sc
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Books on the topic "3-oxadiazol"

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Tremblay, Rose-Marie. Synthesis of 5-methyl-1, 3, 4-oxadiazol-2-carboxylate esters. Laurentian University, 1994.

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Rakaric, Peter. Oligo - 1, 3, 4 - oxadiazoles. Laurentian University, 1998.

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Bradley, Jean-Claude. A study of the reactivity of the carboxyl function in 1, 3, 4-oxadiazole-2-carboxylates. Laurentian University, 1989.

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Book chapters on the topic "3-oxadiazol"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_58.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_59.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_60.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_61.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_62.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(II) complex with 6-(5-methyl-1,2,4-oxadiazol-3-yl)-2,2′-bipyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_63.

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Chen, Chin-Hsiang, Ming-Han Yang, and Wei-Chi Lin. "GaN MIS Photodetectors with l,3-bis [2-(2,20-bipyridin-6–yl) -1,3,4-oxadiazol-5-yl]-benzene (Bpy-OXD) Insulators." In Lecture Notes in Electrical Engineering. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04573-3_138.

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Curtis, A. D. M. "From -(Anilinomethylene)-1,2,4-oxadiazol-3-amines." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-00884.

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von Angerer, S. "Thermolysis of 3-Phenyl-1,2,4-oxadiazol-5-amines." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-017-00808.

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Schantl, J. G. "Reaction of 1,3,4-Oxadiazol-2(3)-one with 2-Azirene." In Heteroatom Analogues of Aldehydes and Ketones. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-027-00687.

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Conference papers on the topic "3-oxadiazol"

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Troitskaya-Markova, Nadezhda, Olga Vlasova та Oleg Rakitin. "4,5-DIOXO-4,5-DIHYDRO-4Λ4,5Λ4-BIS([1,2,5]OXADIAZOLO)[3,4-с:3',4'-e]PYRIDAZINE AS A SYNTHETIC EQUIVALENT OF 4,4'-DINITROSO-3,3'-BI(1,2,5-OXADIAZOLE)". У Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m779.aks-2019/305-307.

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Stadlbauer, Wolfgang, Corinna Gressl, A. Elisabeth Täubl, and Werner Fiala. "Cyclization of 4-Azido-3-nitroquinolines to Oxadiazolo[3,4-c]quinolines." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00487.

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Forostyanko, Anna, Elena Vasileva, and Irina Proskurina. "SYNTHESIS OF 5-(4’-NITROPHENYL)-3-ARYL-1,2,4-OXADIAZOLES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m758.aks-2019/222-226.

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Saleh, R. A., H. A. Mohammad, T. I. Gerber, and E. C. Hosten. "Synthesis and characterization of mono and mixed ligand, Ni(II), Pd(II) and Pt(II) complexes of S-5-phenyl-1, 3, 4-oxadiazole-2-yl benzothioate with some tertiary diphosphines ligands." In 6TH INTERNATIONAL CONFERENCE AND WORKSHOPS ON BASIC AND APPLIED SCIENCES. Author(s), 2017. http://dx.doi.org/10.1063/1.5004324.

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