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1

Ismail, Ismail, Andi Zulkifli Nusri, Asmini Asmini, Herdiansyah Herdiansyah, and Andi Arismanza. "Penerapan Teknologi Mesin Pencacah Sampah dan Biodigester untuk Pembuatan Pupuk Organik dan Biogas." Prima Abdika: Jurnal Pengabdian Masyarakat 3, no. 4 (2023): 465–72. http://dx.doi.org/10.37478/abdika.v3i4.3445.

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One of the most prominent natural resources in Congko Village is agricultural land of around 300.72 hectares, while the area of plantation land managed by the Bulu Mappalasae farmer group reaches 101 hectares consisting of 21 hectares of corn land, 63 hectares of cocoa/cocoa land, and 17 hectares of rice fields. The results of the plantation are unsatisfactory, namely for the cocoa plantation which is only able to produce 500kg/hectare/year. One of the obstacles to the lack of productivity of agricultural products is due to the lack of fertilizer, the amount of fertilizer obtained by farmers a
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2

Harmaen, A. S., A. Khalina, H. Mohd Ali, and I. Nor Azowa. "Thermal, Morphological, and Biodegradability Properties of Bioplastic Fertilizer Composites Made of Oil Palm Biomass, Fertilizer, and Poly(hydroxybutyrate-co-valerate)." International Journal of Polymer Science 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/3230109.

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Slow-release bioplastic fertilizer (BpF) composites were developed by processing oil palm empty fruit bunch (EFB), fertilizer, and poly(hydroxybutyrate-co-valerate) (PHBv) using extrusion techniques with controlled formulation and temperature. The temperature was kept at 150°C for 3 to 5 min during processing using twin-screw extruder. The PHBv lost weight gradually with the increasing temperature and its thermal degradation occurred initially at 263.4°C and reached the maximum at 300.7°C. Scanning electron microscope (SEM) images showed that the bonding of all composites created small gaps be
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3

Stieve, Susan M., and Dennis P. Stimart. "842 PB 482 INFLUENCE OF STOMATA AND TRANSPIRATION ON ANTIRRHINUM MAJUS L. POSTHARVEST LONGEVITY." HortScience 29, no. 5 (1994): 554a—554. http://dx.doi.org/10.21273/hortsci.29.5.554a.

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Eighteen commercially used white Antirrhinum majus (snapdragon) inbreds, a hybrid of Inbred 1 × Inbred 18 (Hybrid 1) and an F2 population (F2) of Hybrid 1 were evaluated for stomatal size and density and transpiration rate to determine their affect on postharvest longevity. Stems of each genotype were cut to 40 cm, placed in distilled water and discarded when 50% of florets wilted or browned. Postharvest longevity of inbreds ranged from 3.7 to 12.9 days; Hybrid 1 and the F2 averaged 3.0 and 9.1 days postharvest, respectively. Leaf impressions showed less than 3% of stomata were found on the ad
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4

Burapan, Supawadee, Mihyang Kim, Yingyong Paisooksantivatana, Bekir Engin Eser, and Jaehong Han. "Thai Curcuma Species: Antioxidant and Bioactive Compounds." Foods 9, no. 9 (2020): 1219. http://dx.doi.org/10.3390/foods9091219.

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For the functional food applications, antioxidant properties and the bioactive compounds of the 23 Curcuma species commercially cultivated in Thailand were studied. Total phenolic content and DPPH radical scavenging activity were determined. The concentrations of eight bioactive compounds, including curcumin (1), demethoxycurcumin (2), bisdemethoxycurcumin (3), 1,7-diphenyl-(4E,6E)-4,6-heptadien-3-ol (4), germacrone (5), furanodienone (6), zederone (7), and ar-turmerone (8), were determined from the Curcuma by HPLC. While the total phenolic content of C. longa was highest (22.3 ± 2.4 mg GAE/g,
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5

Zelchan, Roman, Vladimir Chernov, Anna Medvedeva, et al. "Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [99mTc]Tc(CO)3-(HE)3-Ec1 for Visualization of EpCAM-Expressing Lung Cancer." Cancers 16, no. 16 (2024): 2815. http://dx.doi.org/10.3390/cancers16162815.

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A high level of EpCAM overexpression in lung cancer makes this protein a promising target for targeted therapy. Radionuclide visualization of EpCAM expression would facilitate the selection of patients potentially benefiting from such treatment. Single-photon computed tomography (SPECT) using 99mTc-labeled engineered scaffold protein DARPin Ec1 has shown its effectiveness in imaging tumors with overexpression of EpCAM in preclinical studies, providing high contrast just a few hours after injection. This first-in-human study aimed to evaluate the safety and distribution of [99mTc]Tc(CO)3-(HE)3-
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6

Chauhan, Swati, Neha Jain, Shilani Sharma, Shagun Mehra, and Upendra Nagaich. "Colon Targeted Protein Nanoparticles Loaded Suppositories : Effective against Intestinal Parasites." Advanced Pharmaceutical Bulletin 11, no. 3 (2020): 490–96. http://dx.doi.org/10.34172/apb.2021.056.

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Purpose: The aim of the present investigation was to formulate protein nanoparticles loaded suppositories for colon targeting of metronidazole (MZ), to achieve sustain release effect. Methods: Protein nanoparticles were formulated via desolvation technique by utilizing 2 3 factorial design which results into eight formulations. The synthesized protein nanoparticles were characterized for different physicochemical and in vitro parameters viz. particle size, surface morphology, entrapment efficiency and zeta potential, drug- excipients compatibility studies. Results: The formulated protein nanop
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7

Tang, Yating, Jie Xu, Jiahui Chen, and Yi Lu. "Long-Term Destiny of Corneal Endothelial Cells in Anterior Chamber Intraocular Lens-Implanted Eyes." Journal of Ophthalmology 2020 (December 24, 2020): 1–6. http://dx.doi.org/10.1155/2020/5967509.

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Purpose. To investigate the long-term changes of corneal endothelial cells (EC) in anterior chamber intraocular lens- (AC-IOL-) implanted eyes. Methods. Retrospective study. We included 37 eyes (25 patients) that received AC-IOL implantation previously in the Eye and ENT Hospital of Fudan University between 1995 and 2016. Follow-up outcomes included the best-corrected visual acuity (BCVA), endothelial cell density, hexagonality, coefficient of variance, and central corneal thickness. Results. In total, 23 eyes (62.16%) with phakic and 14 eyes (37.84%) with aphakic AC-IOLs were included. Among
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8

Obaid Al-Shahbani, Ismail Razak, and Muhammad Tarkhan Abu Al-Mikh Al-Mamouri. "Effect of Adding Bio-Fertilizer and Spraying Nano - and Chelated Iron Fertilizer on the Nutrient Content of Orange Seedling Leaves." IOP Conference Series: Earth and Environmental Science 1060, no. 1 (2022): 012012. http://dx.doi.org/10.1088/1755-1315/1060/1/012012.

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Abstract The study was carried out in the certified citrus propagation nursery of the Horticultural and Forestry Company in Al-Hindiya District / Holy Karbala Governorate during the period 20/4/ up to 20/8/2021, in order to study the effect of adding bio-fertilizer and spraying nano and chelated iron fertilizers on the content of orange seedlings leaves of the elements food. The experiment included three factors, the first biological fertilizing factor, adding ground at four levels, which are (the comparison treatment, azotobacter, mycorrhizal fungi, mycorrhizal fungi + azotobacter). It is the
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9

Rivera, E., G. Cremaschi, A. M. Genaro, et al. "Actions of a novel therapeutic formulation: Zn, Se and Mn plus Lachesis Muta venom (O-LM) on radiation deleterious immune effects." Journal of Clinical Oncology 25, no. 18_suppl (2007): 14116. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.14116.

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14116 Background: We have previously reported that O-LM inhibits malignant cell proliferation and increases survival in rodent tumor models (Int J Cancer S13:183, 2002). Molecular and immunological basis of O-LM action were reported (J Clin Oncol 24:18S, 2006). As O- LM selectively protects normal tissues from high doses of ionizing radiation (Proc Int Cancer Congress,1495–9, 1998), we here investigated O- LM protective action upon radiation effects on immune cells. Methods: Balb/c mice (n=15 each group) were employed: control (C); 2Gy whole body irradiated (IR); treated with O-LM (Zn, Se, Mn
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10

Tewari, H. K., P. Sony, R. Chawla, S. P. Garg, and P. Venkatesh. "Prospective Evaluation of Intravitreal Triamcinolone Acetonide Injection in Macular Edema Associated with Retinal Vascular Disorders." European Journal of Ophthalmology 15, no. 5 (2005): 619–26. http://dx.doi.org/10.1177/112067210501500513.

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Purpose To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity and macular thickness using optical coherence tomography (OCT) in macular edema associated with various retinal vascular disorders. Methods This prospective nonrandomized clinical interventional study included 81 eyes (76 patients) comprised of Group I, 57 eyes (51 patients) with diabetic macular edema; Group II, 10 eyes (10 patients) with branch retinal vein occlusion; and Group III, 13 eyes (13 patients) with central retinal vein occlusion. All eyes received an intravitreal injection of 4 mg triamcinolone
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11

Philip, Mary, Edison Y. Chiu, and Janis L. Abkowitz. "Regulation of Flvcr by Macrophages in Response to Lipopolysaccharide." Blood 118, no. 21 (2011): 2111. http://dx.doi.org/10.1182/blood.v118.21.2111.2111.

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Abstract Abstract 2111 Pathogenic bacteria must acquire iron from their hosts to survive and have evolved multiple mechanisms to capture iron or iron-containing heme from the bloodstream or tissues. In response, mammals have developed defense mechanisms to keep iron from pathogens. For example, in response to inflammatory cytokines, hepcidin secreted by the liver binds to the iron exporter ferroportin (FPN1), leading to FPN1 internalization and degradation, decreasing gastrointestinal iron absorption and increasing macrophage iron storage. Much of the body's iron stores are complexed in heme.
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12

Lakatos, L., L. Gonczi, P. Golovics, et al. "P635 Incidence, prevalence, disease phenotype and maximal therapeutic step in Ulcerative Colitis patients in Western Hungary – a population-based study between 2007–2018, data from the Veszprem County cohort." Journal of Crohn's and Colitis 16, Supplement_1 (2022): i554—i555. http://dx.doi.org/10.1093/ecco-jcc/jjab232.758.

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Abstract Background Recent trends indicate a change in the epidemiology of inflammatory bowel disease (IBD) with previously low incidence areas now reporting progressive rise. The number of epidemiological population-based studies are still limited from Eastern Europe. The present study is a continuation of the Veszprem IBD population-based cohort with a follow-up of the incidence and disease course of IBD since 1977. Our aim was to analyze the incidence and disease phenotype at diagnosis, and the maximal therapeutic step distributions during follow-up in a prospective population-based databas
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13

Spronk, Henri M. H., Joanne van Ryn, Christian Zentai, Hugo ten Cate, Rolf Rossaint, and Oliver Grottke. "Resuscitation With Different Volume Expanders Does Not Influence Coagulation After Antidoting Dabigatran With Its Specific Fab In a Pig Model Of Hemorrhagic Shock." Blood 122, no. 21 (2013): 3649. http://dx.doi.org/10.1182/blood.v122.21.3649.3649.

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Abstract Introduction A specific antibody fragment (Fab) is currently in development to reverse the effects of dabigatran in cases of life-threatening bleeding or emergency surgery. In trauma, different volume expanders are used for resuscitation to compensate for blood loss and hemorrhagic shock. The influence of volume expanders on binding of dabigatran to the Fab, however, is not known. Therefore, in this study we investigated whether frequently used infusion solutions affect binding of dabigatran to the Fab antidote and the resulting effects on coagulation assays. Methods All studies were
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14

Calderón-Goercke, M., D. Prieto-Peña, S. Castañeda, et al. "THU0297 SERIOUS INFECTIONS IN 134 PATIENTS WITH GIANT CELL ARTERITIS WITH TOCILIZUMAB IN CLINICAL PRACTICE. FREQUENCY, TYPE AND CLINICAL ASSOCIATIONS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 376.1–377. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2583.

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Background:Infections are the most common adverse event of Tocilizumab (TCZ) in Giant Cell Arteritis (GCA). In GiACTA study(1),serious infections were observed in 7% (9.6/100 patient-years) of patients who received TCZ weekly. Randomized clinical trials (RCTs) are conducted under highly standardized design excluding some real-world patients. Therefore, adverse events may be underestimated in RCTs. In our series of real-life, serious infections occurred in 11.9% (10.6/100 patient-years)(2).Objectives:In a wide series of GCA of clinical practice treated with TCZ, we assess the frequency, type an
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15

Burmester, G. R., K. Winthrop, R. Blanco, et al. "AB0522 SAFETY PROFILE OF UPADACITINIB UP TO 3 YEARS IN PATIENTS WITH PSORIATIC ARTHRITIS: AN INTEGRATED ANALYSIS FROM THE PHASE 3 PROGRAM." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1287–88. http://dx.doi.org/10.1136/annrheumdis-2021-eular.395.

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Background:The efficacy and safety of upadacitinib (UPA), an oral Janus kinase inhibitor, in patients (pts) with active psoriatic arthritis (PsA) were demonstrated through 24 weeks in the phase 3 SELECT-PsA 1 and SELECT-PsA 2 placebo-controlled clinical trials.1,2Objectives:To describe the long-term integrated safety profile of UPA relative to adalimumab (ADA) in pts with PsA treated in the SELECT program.Methods:The SELECT-PsA program enrolled pts with prior inadequate response or intolerance to ≥1 non-biologic DMARD (SELECT-PsA 1) or ≥1 biologic DMARD (SELECT-PsA 2). Both trials include UPA
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16

Arce, Carlos, and Lukáš Krátký. "Comparing the Impact of Knife and Ball Milling of Beech Chips on the Particle Size Characteristics." Waste and Biomass Valorization, May 28, 2025. https://doi.org/10.1007/s12649-025-03119-0.

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Abstract Knife and ball mills are widely used for size reduction in advanced biorefineries. Biomass valorisation processes such as hydrolysis, fermentation, pyrolysis, gasification, and combustion require biomass with specific particle sizes, uniformity, and a narrow distribution for stable and controlled processing. This study compares the particle size distributions of knife- and ball-milled beech chips, focusing on nominal sizes, relative span (RSM), uniformity index, curvature (Cu), and skewness (Cc). The knife mill produced a uniform distribution with RSM values of 1.44 ± 0.09. The ball m
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17

BARAN, Ayşe, and Cumali KESKİN. "Determination of Constituents of Extract of Celtis tournefortii Lam. by LC-MS/MS, Investigation of Enzyme Inhibition, Antimicrobial and Anticancer Effects." International Journal of Pure and Applied Sciences, January 27, 2023. http://dx.doi.org/10.29132/ijpas.1168200.

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Phytochemicals found in extracts obtained from plants are very important bioactive constituents. In this study, phytochemicals in extract content obtained from Celtis tournefortii .Lam. tree (CT) leaves were determined by a LC-MS method. The constituents with the major concentrations was found rutin (2479.89 µg ml-1), coumarin (1241.68 µg ml-1), biochanin A (1026.42 µg ml-1), shikimic acid (477.32 µg ml-1), chlorogenic acid (300.76 µg ml-1). The suppressive effects of CT extract on the growth of pathogenic strains were studied by microdilution method. It was observed that it caused suppression
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18

Faris, Abdurrahman, Evi Liviawaty, Yuli Andriani, and Eddy Affrianto. "Nori Level of Preference with Mixed Sargassum sp. and Eucheuma spinosum Seaweed as Raw Material." Asian Food Science Journal, August 10, 2019, 1–9. http://dx.doi.org/10.9734/afsj/2019/v11i230059.

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This research aimed to obtain the best nori from a mixture of Sargassum sp and Eucheuma spinosum seaweed and the most preferred by panellists. The research's method used in this study is an experimental method with 3 treatments comparing the seaweed between Sargassum sp. and Eucheuma spinosum that is 1:1, 2:1, 3:1 then tests that used are hedonic test with 20 semi-trained panellists who have experience in organoleptic assessment as replications, physical and chemical tests were also tested for the best treatment according to hedonic test. This research was conducted at the Fisheries Product Pr
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Furino, Claudio, Alfredo Niro, Michele Reibaldi, Francesco Boscia, and Giovanni Alessio. "Dexamethasone intravitreal implant along with femtosecond laser assisted cataract surgery in patients with diabetic macular edema and cataract." European Journal of Ophthalmology, December 25, 2022, 112067212211463. http://dx.doi.org/10.1177/11206721221146328.

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Purpose To assess the safety and efficacy of intraoperative dexamethasone intravitreal (DEX) implant in patients with diabetic macular edema (DME) undergoing femtosecond laser assisted cataract surgery (FLACS). Methods In this single-center retrospective study, the charts of patients who underwent combined FLACS and DEX implant in the previous three months were reviewed. Primary outcome measures were ocular complications; secondary outcome measures were the change of best-corrected visual acuity (BCVA) and central retinal thickness (CRT). Results 20 eyes of 20 patients were included. None deve
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Dai, Chen, Hai‐Xing Cao, Jia‐Xin Tian, et al. "Structural‐guided design to improve the catalytic performance of aldo‐keto reductase KdAKR." Biotechnology and Bioengineering, August 29, 2023. http://dx.doi.org/10.1002/bit.28535.

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AbstractAldo‐keto reductases (AKRs) are important biocatalysts that can be used to synthesize chiral pharmaceutical alcohols. In this study, the catalytic activity and stereoselectivity of a NADPH‐dependent AKR from Kluyveromyces dobzhanskii (KdAKR) toward t‐butyl 6‐chloro (5S)‐hydroxy‐3‐oxohexanoate ((5S)‐CHOH) were improved by mutating its residues in the loop regions around the substrate‐binding pocket. And the thermostability of KdAKR was improved by a consensus sequence method targeted on the flexible regions. The best mutant M6 (Y28A/L58I/I63L/G223P/Y296W/W297H) exhibited a 67‐fold highe
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21

Nutini, I., D. Q. Adams, C. Alduino, et al. "Latest Results from the CUORE Experiment." Journal of Low Temperature Physics, October 8, 2022. http://dx.doi.org/10.1007/s10909-022-02873-y.

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AbstractThe Cryogenic Underground Observatory for Rare Events (CUORE) is the first cryogenic experiment searching for $$0\nu \beta \beta $$ 0 ν β β decay that has been able to reach the one-tonne mass scale. The detector, located at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy, consists of an array of 988 $${\mathrm{TeO}}_{2}$$ TeO 2 crystals arranged in a compact cylindrical structure of 19 towers. CUORE began its first physics data run in 2017 at a base temperature of about 10 mK and in April 2021 released its $$3{\mathrm{rd}}$$ 3 rd result of the search for $$0\nu \beta \beta $$
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Su, Hanyu, and Guoying Li. "Tanning with Aluminum-Gallic Acid Complex." Journal of the American Leather Chemists Association 116, no. 3 (2021). http://dx.doi.org/10.34314/jalca.v116i3.4250.

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To figure out how polyphenol compounds with a low molecular weight helped in aluminum tannage, a complex of gallic acid and aluminum as well as its application to the tanning of hide powder was studied in this paper. Precipitation points of aluminum chloride solution with different concentrations of gallic acid were measured to guide the basification in hide powder tannage. UV-Visible spectra showed that gallic acid and aluminum would form soluble complexes in aqueous solution and the complexation reaction was pH reliable. Through stoichiometry studies, generations of the 1:2 complex under pH
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23

Vasanthi, Suraj S., Nyzil Massey, Suresh N. Nair, Jonathan P. Mochel, Lucas Showman, and Thimmasettappa Thippeswamy. "Exploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare." Frontiers in Veterinary Science 10 (November 9, 2023). http://dx.doi.org/10.3389/fvets.2023.1297221.

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Saracatinib/AZD0530 (SAR), a Src tyrosine kinase inhibitor, mitigates seizure-induced brain pathology in epilepsy models upon repeated oral dosing. However, repeated dosing is stressful and can be challenging in some seizing animals. To overcome this issue, we have incorporated SAR-in-Diet and compared serum pharmacokinetics (PK) and brain concentrations with conventional repeated oral dosing. Saracatinib in solution or in-diet was stable at room temperature for >4 weeks (97 ± 1.56%). Adult Sprague Dawley rats on SAR-in-Diet consumed ~1.7 g/day less compared to regular diet (16.82 ± 0.6
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Guan, Lihua, Huijing Zhao, Kai Wang, Ke-qin Zhang, and Kai Meng. "PLCL-TPU bi-layered artificial blood vessel with compliance matching to host vessel." Journal of Biomaterials Applications, July 5, 2023. http://dx.doi.org/10.1177/08853282231188424.

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Compliance mismatch between the artificial blood vessel and the host vessel leads to abnormal hemodynamics and is a major mechanical trigger of intimal hyperplasia. Efforts have been made to achieve higher compliance of artificial blood vessels. However, the preparation of artificial blood vessels with compliance matching to host vessels has not been realized. A bi-layered artificial blood vessel was successfully prepared by dip-coating and electrospinning composite method using poly(L-Lactide-co-caprolactone) (PLCL) and thermoplastic poly(ether urethane) (TPU). In the case of a certain wall t
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Stepanov, Alexandr, Jan Studnicka, Miroslav Veith, et al. "Incidence of adverse events after loading phase of the brolucizumab therapy of neovascular AMD: Real-life evidence in the Czech Republic." European Journal of Ophthalmology, October 17, 2022, 112067212211326. http://dx.doi.org/10.1177/11206721221132619.

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Aim To evaluate the incidence of ocular adverse events after loading phase of the brolucizumab therapy in patients with neovascular age-related macular degeneration (nAMD) in real-life clinical practice – in treatment-naive patients and in patients after switching from another anti-VEGF agent. Another aim was to evaluate treatment outcomes in patients with adverse events. Methods This is a multicentre, retrospective, observational study from 16 application centres in the Czech Republic. Patients diagnosed with nAMD were treated with brolucizumab in a fixed regimen of loading phase (3 injection
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K. UMESHA and S. PURSHOTAM. "Response of fodder cowpea (Vigna unguiculata) varieties to application of phosphorus." Indian Journal of Agronomy 41, no. 4 (2001). http://dx.doi.org/10.59797/ija.v41i4.3726.

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Identification of suitable varieties of cow- The soil was red acidic in reaction, me- pea [I/igrza unguiculata (L.) Walp.] for fod: dium in organic carbon (0.69%) and avail- der purpose and their nutritional require- able N (300 kglha), low in available P(6.2 ments specially of phosphorus is important kglha) and rich in available K (295 kgtha). for obtaining higher forage yields under There was a long drought ~~ell(33.8 mi,,- rainfed conditions. heref fore an attempt in 7 rainy days) from mid-June to mid-sep< was made to evaluate the comparative per- tember. The crop was sown on 18 Septem-
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27

Burke, Dany, Michael Michael Mayette, and Andre Begin. "Posterior Reversible Encephalopathy Syndrome Due To Carcinoid Crisis Complicating Transarterial Chemoembolization for Metastatic Carcinoid Tumour." Canadian Journal of General Internal Medicine 12, no. 1 (2017). http://dx.doi.org/10.22374/cjgim.v12i1.165.

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Introduction: We present a case report of posterior reversible leukoencephalopathy syndrome (PRES) following transarterial chemoembolization (TACE) of liver metastasis of an intestinal neuroendocrine tumour.Case presentation: A 62-year-old female was evaluated for progressive bilateral vision loss following transarterial chemoembolization (TACE) of hepatic metastasis of a midgut carcinoid tumour with cisplatin. Vital signs were remarkable for significant hypertension (170-210/85-110) since having undergone TACE (baseline BP 136/74), despite pre-procedure administration of octreotide. Blood pre
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