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Journal articles on the topic '302.23/45/082'

Author: Grafiati

Published: 25 July 2024

Last updated: 31 July 2025

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1

Ziani, F., S. A. Brahmi, L. Amaadour, et al. "P-082 Gastric cancer in Moroccan patients aged 45 years or younger: Clinicopathological features and prognosis." Annals of Oncology 26 (June 2015): iv23. http://dx.doi.org/10.1093/annonc/mdv233.82.

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ADENEKAN, SHOLA. "CHANTAL ZABUS, Out in Africa: same-sex desire in sub-Saharan literatures & cultures. Woodbridge: James Currey (hb £45 – 978 1 84701 082 7). 2013, 292 pp." Africa 85, no. 3 (2015): 552–54. http://dx.doi.org/10.1017/s0001972015000406.

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Oliver, Jonathan M., Dustin P. Joubert, Steven E. Martin, and Stephen F. Crouse. "Oral Creatine Supplementation’s Decrease of Blood Lactate During Exhaustive, Incremental Cycling." International Journal of Sport Nutrition and Exercise Metabolism 23, no. 3 (2013): 252–58. http://dx.doi.org/10.1123/ijsnem.23.3.252.

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Purpose:To determine the effects of creatine supplementation on blood lactate during incremental cycling exercise.Methods:Thirteen male subjects (M ± SD 23 ± 2 yr, 178.0 ± 8.1 cm, 86.3 ± 16.0 kg, 24% ± 9% body fat) performed a maximal, incremental cycling test to exhaustion before (Pre) and after (Post) 6 d of creatine supplementation (4 doses/d of 5 g creatine + 15 g glucose). Blood lactate was measured at the end of each exercise stage during the protocol, and the lactate threshold was determined as the stage before achieving 4 mmol/L. Lactate concentrations during the incremental test were

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Xiao, Yu-Tian, Xianzhi Zhao, Yifan Chang, et al. "Assessing the safety and feasibility of neoadjuvant hormone and radiation therapy followed by robot-assisted radical prostatectomy for treating locally advanced prostate cancer: protocol for an open-label, dose-escalation, single-centre, phase I clinical trial." BMJ Open 10, no. 11 (2020): e038678. http://dx.doi.org/10.1136/bmjopen-2020-038678.

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IntroductionPatients with locally advanced prostate cancer are at high risk of recurrence after definitive treatment. There are emerging data that radical prostatectomy can delay the progression of castration resistance and potentially prolong survival. Neoadjuvant radiation therapy improves local control and has shown survival benefit with favourable toxicity profiles in several other malignancies. We have designed this trial to investigate whether this combination, which theoretically maximises local control, is a safe and feasible approach for treating locally advanced prostate cancer.Metho

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Yvernault, Martine. "William Perry MARVIN, Hunting Law and Ritual in Medieval English Literature , Woodbridge, Brewer, 2006 ; 1 vol., X-198 p. ISBN : 1-84434-082-0. Prix : GBP 45 ; USD 80." Le Moyen Age Tome CXIV, no. 3 (2009): LXVIII. http://dx.doi.org/10.3917/rma.143.0647zzp.

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Benndorf, J. "RAINER STAWIKOWSKI und UWE WERNER: Die Buntbarsche der Neuen Welt — Südamerika.— 288 S., 176 Farb- und 105 Schwarzweißphotos. Stuttgart: Verlag Eugen Ulmer 1988. ISBN 3–87401–082–1. DM 45,—." Internationale Revue der gesamten Hydrobiologie und Hydrographie 75, no. 5 (1990): 694. http://dx.doi.org/10.1002/iroh.19900750531.

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Elías, Rudy. "International programs for the evaluation of academic achievements and their influence on educational policies in Latin America." Población y Desarrollo 23, no. 45 (2017): 74–82. http://dx.doi.org/10.18004/pdfce/2076-054x/2017.023(45)074-082.

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Ikuta, Keiko, Shunsaku Nakagawa, Kenji Momo, et al. "Association of proton pump inhibitors and concomitant drugs with risk of acute kidney injury: a nested case–control study." BMJ Open 11, no. 2 (2021): e041543. http://dx.doi.org/10.1136/bmjopen-2020-041543.

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ObjectivesThis study aimed to assess whether the combined use of proton pump inhibitors (PPIs) with non-steroidal anti-inflammatory drugs (NSAIDs) or antibiotics (penicillins, macrolides, cephalosporins or fluoroquinolones) was associated with an increased risk of acute kidney injury (AKI).DesignA nested case–control study.SettingA health insurance claims database constructed by the Japan Medical Data Center.ParticipantsPatients were eligible if they were prescribed a PPI, NSAID and antibiotic at least once between January 2005 and June 2017. The patients who were new PPI users and did not hav

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Bandapadya, Koushik, Md Nurunnabi sarker, Areyfin Mohammed Yoshi, Ashrafuzzaman Hera, and Md Omar Faruque. "Global analysis of active defense technologies for unmanned aerial vehicle." American Journal of Engineering and Technology 7, no. 1 (2025): 41–53. https://doi.org/10.37547/tajet/volume07issue01-07.

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This paper explores active defense for UAVs globally, with the main emphasis on detection and countermeasure technologies. Questionnaires were administered to 139 individuals in the USA, and the results were analyzed with the help of the Statistic Package for Social Sciences (SPSS), including reliability analysis, descriptive frequency, and regression analysis. The results concerning Hypothesis 1 concerning technological detection impact on the adequacy of UAV defense are the following. Analyzing the data, it was established that detection technology influences UAV defense significantly with F

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Aung, Si Thu, Wint Wint Nyunt, Myat Myat Moe, Htin Lin Aung, and Thandar Lwin. "The fourth national tuberculosis prevalence survey in Myanmar." PLOS Global Public Health 2, no. 6 (2022): e0000588. http://dx.doi.org/10.1371/journal.pgph.0000588.

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Tuberculosis (TB) remains a significant cause of morbidity and mortality in Myanmar. The fourth National TB Prevalence Survey was conducted in 2017–2018 to determine the actual burden of TB not only at the national level but also for three subnational strata (the states, regions other than Yangon, and the Yangon region) and develop a more efficacious country strategy on TB care and control. One hundred and thirty eight clusters were selected by population proportionate sampling. Adult (≥15 years of age) residents having lived for 2 weeks or more in the households of the selected clusters were

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Miller, Joseph, Bernard Cook, Satheesh Gunaga, et al. "Health Care Resource Utilization for Patients With Suspected Myocardial Infarction." JAMA Network Open 8, no. 4 (2025): e256930. https://doi.org/10.1001/jamanetworkopen.2025.6930.

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ImportanceEvaluation for myocardial infarction (MI) in emergency departments (EDs) is a common, resource-intensive process. High-sensitivity cardiac troponin I (hs-cTnI) assays have become a key tool in rapidly ruling out MI, with the potential to reduce health care resource utilization.ObjectiveTo determine whether a 0-hour and 1-hour (hereafter referred to as 0/1-hour) hs-cTnI accelerated protocol reduces health care resource utilization compared with a traditional 0/3-hour standard care protocol for MI exclusion in the ED.Design, Setting, and ParticipantsThis is a prespecified secondary ana

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Moccia, Moccia A., Jane Donaldson, Mukesh Chhanabhai, et al. "The International Prognostic Factor Project Score (IPS) in Advanced Stage Hodgkin Lymphoma Has Limited Utility in Patients Treated in the Modern Era." Blood 114, no. 22 (2009): 1554. http://dx.doi.org/10.1182/blood.v114.22.1554.1554.

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Abstract Abstract 1554 Poster Board I-577 Introduction The International Prognostic Factor Project Score (IPS) is the most widely utilized risk stratification index for Hodgkin lymphoma (HL) (Hasenclever, N Engl J Med, 1998). Based on patients treated before 1992, it incorporates 7 adverse risk features (male gender, age ≥45 y, stage IV, hemoglobin <105 g/L, WBC ≥15 × 109/L, lymphocyte count <0.6 × 109/L or <8% of differential, albumin <40 g/L) and predicts for a 5-year freedom-from progression (FFP) ranging from 42-84%.The IPS has not been validated in a more recently treated popu

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BLACK, J. M. W., F. A. BARAGAR, and D. S. CHANASYK. "A MATHEMATICAL MODEL TO ESTIMATE AGGREGATE BREAKDOWN DURING SOIL SIEVING IN A MODIFIED RAPD3 ROTARY SIEVE." Canadian Journal of Soil Science 69, no. 4 (1989): 817–24. http://dx.doi.org/10.4141/cjss89-082.

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The percentage of soil material > 0.84 mm obtained by dry sieving is commonly used as an index of the wind erodibility of soils. Present sieving procedures do not account for the breakdown of friable aggregates during sieving so that results do not necessarily represent aggregation in the original sample. An equation was fitted to soil sieving data from a modified rapid rotary sieve. It successfully evaluated aggregate attrition during sieving for 397 out of 404 samples representing a wide variety of textures. Good reproducibility of results using the methodology was obtained for 45 paired

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Kawahara, Naoko, Hisayoshi Ikatsu, Hiroshige Kawata, Shin-ichi Miyoshi, Ken-ichi Tomochika, and Sumio Sinoda. "Purification and characterization of 2-ethoxyphenol-induced cytochrome P450 fromCorynebacteriumsp. strain EP1." Canadian Journal of Microbiology 45, no. 10 (1999): 833–39. http://dx.doi.org/10.1139/w99-082.

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A soluble cytochrome P450 (P450EP1A) induced by 2-ethoxyphenol was purified to apparent homogeneity from Corynebacterium sp. strain EP1. The P450EP1Ashowed a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis with a molecular weight of about 45 kDa. The CO-reduced difference spectra of P450EP1Ahad a Soret maximum at 447.6 nm. The substrate difference spectra with 2-ethoxyphenol showed an absorption maximum at 394.0 nm. The purified P450EP1Adegraded 2-ethoxyphenol in an assay system composed of spinach ferredoxin-NADP+oxidoreductase and NADPH. The reaction activity decreas

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Lupwayi, N. Z., G. W. Clayton, J. T. O’Donovan, K. N. Harker, T. K. Turkington, and W. A. Rice. "Decomposition of crop residues under conventional and zero tillage." Canadian Journal of Soil Science 84, no. 4 (2004): 403–10. http://dx.doi.org/10.4141/s03-082.

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Field experiments were conducted to determine decomposition patterns of red clover (Trifolium pratense), field pea (Pisum sativum), canola (Brassica rapa) and wheat (Triticum aestivum) residues under zero and conventional tillage. Crop residue amounts produced in 2 trial years ranged from 1.6 t ha-1 for monoculture wheat to 6.05 t ha-1 for peas, and tillage had no effect. The extent of dry matter (DM) decomposition was usually less under zero than under conventional tillage, e.g., 31 to 41% of canola DM decomposed under zero tillage while 41 to 50% decomposed under conventional tillage in 12 m

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Donald, David B., William T. Aitken, Carrie Paquette, and Shaun S. Wulff. "Winter snowfall determines the occupancy of northern prairie wetlands by tadpoles of the Wood Frog (Lithobates sylvaticus)." Canadian Journal of Zoology 89, no. 11 (2011): 1063–73. http://dx.doi.org/10.1139/z11-082.

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In the northern plains of North America, the wetland breeding habitat of amphibians and their populations could be reduced by a change in climate that included decreased precipitation. To test this hypothesis, relative abundance of late-stage tadpoles of the Wood Frog ( Lithobates sylvaticus (LeConte, 1825)) was monitored from 1997 to 2010 during a wet–dry–wet cycle in 29 wetlands distributed throughout central Saskatchewan, Canada. The wetlands were dry for up to 7 consecutive years, and for a mean of 3.8 consecutive years. Consequently, tadpole occupancy of the wetlands was reduced to less t

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Lawrence, Derek Joseph, N. Luckai, W. L. Meyer, et al. "Distribution of white spruce lateral fine roots as affected by the presence of trembling aspen: root mapping using simple sequence repeat DNA profiling." Canadian Journal of Forest Research 42, no. 8 (2012): 1566–76. http://dx.doi.org/10.1139/x2012-082.

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Mixedwood forests of white spruce ( Picea glauca (Moench) Voss) and trembling aspen ( Populus tremuloides Michx.) may possess ecological advantages over monospecific white spruce stands. Belowground competition may be reduced through vertically stratified roots; facilitation of growth may occur in upper soil layers through nutrient-rich trembling aspen litterfall. These effects may incentivize white spruce to preferentially exploit upper soil layers in mixedwood stands, resulting in wider root systems. This research contrasted white spruce fine root (diameter <2 mm) distributions in organic

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De Brito, Rávilla Endy da Rocha Cunha, and Ruth Silva Lima Da Costa. "LACAZIOSE (DOENÇA DE JORGE LOBO): UM RELATO DE CASO." REVISTA FOCO 17, no. 1 (2024): e4150. http://dx.doi.org/10.54751/revistafoco.v17n1-082.

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A lacaziose, também conhecida como doença de Jorge Lobo, é uma doença de granulomatosa de caráter crônico, que é causada quando há implantação traumática do fungo Lacazia loboi no tecido cutâneo e subcutâneo. A doença acontece mais em regiões de clima quente e úmido, sendo que, no Brasil, é mais registrada na região amazônica. É observado que são mais acometidas pessoas do sexo masculino, com idade entre 20 e 45 anos, que trabalham em área rural e/ou de floresta. A apresentação clínica é dada, principalmente, por lesões nodulares queloidianas. Os locais mais acometidos são os membros e a face

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UKRAINETZ, H., C. A. CAMPBELL, R. P. ZENTNER, and M. MONREAL. "RESPONSE OF BROMEGRASS TO N, P AND S FERTILIZER ON A GRAY LUVISOLIC SOIL IN NORTHWESTERN SASKATCHEWAN." Canadian Journal of Plant Science 68, no. 3 (1988): 687–703. http://dx.doi.org/10.4141/cjps88-082.

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A 9-yr study was conducted on a Gray Luvisolic loam at Loon Lake, Saskatchewan to determine the effect of ammonium nitrate-N (34–0–0) and urea-N (46–0–0) on bromegrass (Bromus inermis Leyss.) production and nutrient quality, N recovery, and N use efficiency when the N was applied either annually or as a single application at the start of the experiment. The effects of phosphorus (P) and sulphur (S) were also assessed. Each N source was applied at single rates of 0, 100, 200, 400 and 800 kg ha−1 N and annual rates of 0, 50, 100 and 200 kg ha−1 N. The ammonium nitrate was also applied as a singl

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Blank, N., J. Henes, T. Kallinich, et al. "POS1380 LONG-TERM EFFICACY AND SAFETY OF CANAKINUMAB IN PATIENTS WITH TRAPS (TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PERIODIC SYNDROME) - INTERIM ANALYSIS OF THE RELIANCE REGISTRY." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 972–73. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3808.

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Background:Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is a rare autoinflammatory condition characterized by severe systemic and organ inflammation. In a phase 3 pivotal trial (CLUSTER study), TRAPS patients have been successfully treated with the interleukin-1β inhibitor canakinumab. 45% of patients reached clinical remission after 16 weeks (primary endpoint)1. Canakinumab has been approved and applied for the treatment of TRAPS patients since 20172.Objectives:The present study explores the long-term efficacy and safety of canakinumab under routine clinical practice co

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Chiappella, Annalisa, Benedetta Puccini, Marianna Rossi, et al. "Mantle Cell International Prognostic Index (MIPI) Is a Strong Predictor of the Outcome of Mantle Cell Lymphoma (MCL) in the Rituximab (R) Era." Blood 114, no. 22 (2009): 2928. http://dx.doi.org/10.1182/blood.v114.22.2928.2928.

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Abstract Abstract 2928 Poster Board II-904 Introduction: A new prognostic clinical index (MIPI) and a biological one with cell proliferation (Ki-67) evaluation (MIPIb), were defined specifically for MCL to give a more reliable estimation of outcome (Hoster 2008). Aim of our analysis was to test MIPI and MIPIb on a retrospective series of MCL patients treated with R-chemotherapy. Patients and methods: Between 1999 and 2008, 136 MCL at diagnosis consecutively treated in five institutions entered into the study. Histology was centrally reviewed. Clinical characteristics were: median age 62 (37-84

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Petrie, Mark J., Joseph P. Fleskes, Mike A. Wolder, Craig R. Isola, Gregory S. Yarris, and Daniel A. Skalos. "Potential Effects of Drought on Carrying Capacity for Wintering Waterfowl in the Central Valley of California." Journal of Fish and Wildlife Management 7, no. 2 (2016): 408–22. http://dx.doi.org/10.3996/082015-jfwm-082.

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Abstract We used the bioenergetics model TRUEMET to evaluate potential effects of California's recent drought on food supplies for waterfowl wintering in the Central Valley under a range of habitat and waterfowl population scenarios. In nondrought years in the current Central Valley landscape, food supplies are projected to be adequate for waterfowl from fall through early spring (except late March) even if waterfowl populations reach North American Waterfowl Management Plan goals. However, in all drought scenarios that we evaluated, food supplies were projected to be exhausted for ducks by mi

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Pegu, Bhaba Kumar, Limpon Bora, Jyoti Prava Engty, and Devid Kardong. "Impact of submerged culture different parameters on growth and naringinase activity of Bacillus amyloliquefaciens D1 isolated from citrus gardens of North-East India." ECOLOGY, ENVIRONMENT AND CONSERVATION 30, Suppl (2024): S540—S548. http://dx.doi.org/10.53550/eec.2024.v30i05s.082.

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The study aims at screening, isolation, and characterization of naringinase enzyme producing bacterial strains from soil samples. In this study, 45 bacterial isolates were screened for naringinase activity, and among them, 20 bacterial isolates are found to be capable of naringinase production in liquid mineral medium. Bacterial isolate D1 exhibited the highest naringinase activity in liquid mineral medium. Based on the morphological, biochemical, fatty acid profile, and molecular characterization, bacterial isolate D1 was identified as Bacillus amyloliquefaciens. Impact of different submerged

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Maharramov, S. "Econometric Assessment of Azerbaijan's Logistics Capabilities in Terms of Relations with Turkic-Speaking States." Economic Herald of the Donbas, no. 4 (66) (2021): 45–52. http://dx.doi.org/10.12958/1817-3772-2021-4(66)-45-52.

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Modern world grows very fast every day. The main arrow of every state economy is logistics sector, which is increasing very dynamically. The Turkic Speaking States are locating on the Historical Great Silk Road. The total of territory and population of those countries are 4 732 082 km2 and 157 949 505 people. After collapsing the USSR, the five Turkic Speaking States get independence (Azerbaijan, Kazakhstan, Uzbekistan, Turkmenistan and Kyrgyzstan), economy and political policy of those states have been changed to the modern market rules. The most of those countries economy base on the raw mat

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Wilson, Andrew. "Detritus, disease and death in the city - Xavier Dupré Raventós y Josep-Anton Remolà, SORDES URBIS. LA ELIMINACIÓN DE RESIDUOS EN LA CIUDAD ROMANA. ACTAS DE LA REUNIÓN DE ROME (15-16 DE NOVIEMBRE DE 1996) (Bibliotheca Italica: Monografías de la Escuela Española de Historia y Arqueología en Roma n° 24; L'Erma di Bretschneider, Roma 2000). Pp. xv + 150, 38 figs. ISBN 88-8265-082-0. - Valerie M. Hope and Eireann Marshall (edd.), DEATH AND DISEASE IN THE ANCIENT CITY (Routledge, London 2000). Pp. xii + 194. ISBN 0-415-21427-0. £45." Journal of Roman Archaeology 15 (2002): 479–84. http://dx.doi.org/10.1017/s1047759400014264.

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Jain, Anoop, Helen O. Pitchik, Rockli Kim, S. V. Subramanian, and M. Maria Glymour. "Examining the association between toilet access and major depression among older adults in India: a cross-sectional analysis of the Longitudinal Aging Study in India from 2017 to 2018." Age and Ageing 54, no. 7 (2025). https://doi.org/10.1093/ageing/afaf170.

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Abstract Inadequate access to toilets, which often results in open defecation, could be a risk factor for depression among India’s older and ageing population. Using cross-sectional data from the Longitudinal Aging Study in India from 2017 to 2018, we assessed associations between the lack of a toilet and major depression among 64 082 women and men above the age of 45. In our adjusted multilevel model, we found no association between the lack of a household toilet and the risk of major depression (OR = 0.94, 95% CI: 0.79 to 1.11). We also found no association when we stratified by respondent’s

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Monaghan, Patrick G., William M. Murrah, Kristina A. Neely, Harrison C. Walker, and Jaimie A. Roper. "Exploring age-related differences in the relationship between spatial and temporal contributions to step length asymmetry during split-belt adaptation." Experimental Brain Research, October 24, 2024. http://dx.doi.org/10.1007/s00221-024-06929-1.

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AbstractGait adaptability is crucial for meeting environmental demands, and impaired gait adaptation increases fall risk, particularly in older adults. While prior research exists on older adults’ gait adaptation, particularly in perturbation studies, the specific contributions of temporal and spatial adaptation strategies to step length asymmetry (SLA) during split-belt treadmill walking require further examination. This study fills this gap by evaluating how distinct adaptation strategies contribute to SLA in healthy young and older adults. 19 healthy young adults (20.4 ± 1.1 years) and 19 h

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Brennand, Erin A., Natalie V. Scime, Rebecca Manion, and Beili Huang. "Unilateral Oophorectomy and Age at Natural Menopause: A Longitudinal Community‐Based Cohort Study." BJOG: An International Journal of Obstetrics & Gynaecology, October 10, 2024. http://dx.doi.org/10.1111/1471-0528.17980.

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ABSTRACTObjectiveTo determine the association between unilateral oophorectomy (UO) and age at natural menopause.DesignSecondary analysis of survey data from Alberta's Tomorrow Project (2000–2022).SettingProspective cohort study in Alberta, Canada.Population23 630 women; 548 experienced UO and 23 082 did not experience UO.MethodsFlexible parametric survival analysis was used to analyse age at natural menopause, and logistic regression was used to analyse early menopause and premature ovarian insufficiency by UO status, controlling for birth year, parity, age at menarche, past infertility, hormo

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Moya-Salazar, Jeel, Marleny Ccorahua, Eliane A. Goicochea-Palomino, Jeel G. Moya-Espinoza, and Hans Contreras-Pulache. "Favorable Attitudes Toward Research in Nursing Students During Internship: A Cross-Sectional Study in Peru." SAGE Open Nursing 9 (January 2023). http://dx.doi.org/10.1177/23779608231206776.

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Introduction and objective Research attitudes among nursing students are essential to improve the quality of care and promote evidence-based practice. The objective of this study was to determine the attitude towards research of nursing students during their undergraduate internship and explore the demographic and study-related factors that may affect these attitudes. Materials and Methods In this cross-sectional retrospective study, 100 nursing interns who are >18 years old, currently studying and working, and have a prior academic background were included. To assess the attitudes toward r

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Green, Zachary D., Casey S. John, Anneka Blankenship, et al. "Brain glucose metabolism changes acutely following exercise and tracks with the systemic lactate response." Alzheimer's & Dementia 20, S6 (2024). https://doi.org/10.1002/alz.091743.

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AbstractBackgroundAerobic exercise may positively affect brain health, although relationships with cognitive change are mixed. This likely is due to individual differences in the systemic physiological response to exercise. However, the acute effects of exercise on brain metabolism and biomarker responses are not well characterized in older adults or cognitively impaired individuals.MethodThe Acute Exercise Response on Brain Imaging and Cognition (AEROBIC) study is a randomized, controlled trial (NCT04299308). We enrolled older adults (60+years) who were cognitively healthy (n = 30) or cogniti

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Heitkamp, Christian, Fabian Flottmann, Tobias D. Faizy, et al. "General Anesthesia Versus Conscious Sedation in Thrombectomy Patients With Low NIHSS Anterior Circulation Stroke." Stroke, March 25, 2025. https://doi.org/10.1161/strokeaha.124.049358.

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BACKGROUND: The optimal anesthetic approach for patients with acute ischemic stroke with large vessel occlusion but low National Institutes of Health Stroke Scale receiving mechanical thrombectomy remains unclear. We aimed to evaluate the association of anesthetic strategies with procedural and clinical outcomes, hypothesizing that conscious sedation/local anesthesia (CS/LA) may offer a more favorable risk-benefit ratio than general anesthesia (GA). METHODS: Multicenter cohort study screening all thrombectomy patients prospectively enrolled in GSR-ET (German Stroke Registry-Endovascular Treatm

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Champagne, Gabriel, Julien Dartus, Stéphane Pelet, Bogdan A. Matache, and Etienne L. Belzile. "Patient Factors Influencing Outcomes at 12-Year Follow-up of Hip Arthroscopy for Femoroacetabular Impingement." American Journal of Sports Medicine, August 13, 2024. http://dx.doi.org/10.1177/03635465241265721.

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Background: Arthroscopic treatment of femoroacetabular impingement has increased in popularity since the early 2000s when it was first described, although only a few midterm follow-up studies have been published. Purpose: To describe the outcomes of patients undergoing hip arthroscopy for femoroacetabular impingement at a mean 12-year follow-up and to determine the risk factors for failure. Study Design: Case-control study; Level of evidence, 3. Methods: The Non-Arthritic Hip Score (NAHS) and a radiographic evaluation were completed preoperatively and at midterm follow-up. Participants were di

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Schoueri, Jean Henri Maselli, Clarisse Kaori Fujishige, Luiz Vinicius de Alcantara Sousa, et al. "Melanoma mortality in Brazil: Insights from over 25 years of data and the impact of limited immunotherapy access in the public health system." Journal of Clinical Oncology 43, no. 16_suppl (2025). https://doi.org/10.1200/jco.2025.43.16_suppl.e22582.

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e22582 Background: Skin cancer is the most common cancer globally and in Brazil – and melanoma, its deadliest form. Despite advancements in Immunotherapy (IO) and Target-therapy (TT), these are mostly unavailable in Brazil’s Public Health System (PHS). Methods: Ecological study using secondary data (1996-2023) from Brazil’s PHS. Mortality rates were standardized by WHO’s population and calculated per 100,000 inhabitants. Linear regression analyzed mortality trends by region, using 2011 as a cutoff (IO and TT year of approval). Results: Between 1996-2023, 39,606 deaths occurred due to melanoma

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Lin, Jason, and Yeong-Liang Lin. "pH-dependent drug interactions with acid reducing agents." Journal of Emerging Investigators, 2024. http://dx.doi.org/10.59720/24-082.

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Gastric acid reducing agents (ARAs) are drugs used for treating peptic ulcer disease. The higher gastric pH caused by ARAs can decrease solubility and absorption of the drugs co-administered with ARAs. The study examines the relationship between solubility and pharmacokinetic (PK) changes of cancer drugs concurrently used with ARAs, and the subsequent dose adjustment of cancer drugs to account for drug interactions. We hypothesize that (1) cancer drugs with pH-dependent solubility are evaluated more for drug interactions with ARAs, as compared to those with pH-independent solubility, (2) a dec

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Kharma, Nadir, Stefan Roehrig, Ahmed Atef Shible, et al. "Anticoagulation in critically ill patients on mechanical ventilation suffering from COVID-19 disease, The ANTI-CO trial: A structured summary of a study protocol for a randomised controlled trial." Trials 21, no. 1 (2020). http://dx.doi.org/10.1186/s13063-020-04689-1.

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Abstract Objectives To assess the effect of anticoagulation with bivalirudin administered intravenously on gas-exchange in patients with COVID-19 and respiratory failure using invasive mechanical ventilation. Trial design This is a single centre parallel group, superiority, randomized (1:1 allocation ratio) controlled trial. Participants All patients admitted to the Hamad Medical Corporation -ICU in Qatar for COVID-19 associated respiratory distress and in need of mechanical ventilation are screened for eligibility. Inclusion criteria: all adult patients admitted to the ICU who test positive f

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Rugescu, I. A., R. Dumitrescu, D. Dinu Draganescu, et al. "P-082 Estradiol levels in idiopathic male infertility." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.447.

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Abstract Study question Investigating estradiol in relation with other sperm parameters might reveal new correlations which would help our understanding of male idiopathic infertility Summary answer Statistical significance was found in a series of correlations of E2 levels and sperm, hormonal and health parameters What is known already Male infertility is a rising major health concern, with sperm counts decreasing by 50-60% in the recent decades. The causes for male infertility are very different (genetic, systemic, neurological, infections, trauma, etc.), but at least 44% of cases are idiopa

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Campos Rodero, D., L. Diez-Tercero, C. Berenguer, et al. "O-082 Discrepancies between vaginal and endometrial microbiomes in IVF patients: implications for reproductive success." Human Reproduction 40, Supplement_1 (2025). https://doi.org/10.1093/humrep/deaf097.082.

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Abstract Study question Can vaginal microbiome analysis predict endometrial microbiome status in IVF patients? Summary answer Only 38% of paired vaginal and endometrial samples showed correlation, indicating that vaginal microbiome analysis cannot accurately predict endometrial microbiome status. What is known already A healthy vaginal microbiome is predominantly composed by Lactobacillus species and low presence of other bacteria, since Lactobacillus has specific properties (production of lactic acid and bacteriocins) that allow to create a protective environment and prevent colonization by p

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Cho, H., K. Park, Y. Kim, T. Park, and S. Cho. "B-082 Clinical Investigation of Rods and Rings Pattern in Anti-Nuclear Antibody Test in Korean Patients." Clinical Chemistry 70, Supplement_1 (2024). http://dx.doi.org/10.1093/clinchem/hvae106.444.

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Abstract Background In the mid-2000s, a novel pattern in antinuclear antibody (ANA) testing was reported. Indirect immunofluorescence assays on HEp-2 cells, conducted with sera from patients with Hepatitis C virus (HCV) infection, revealed cytoplasmic structures in the form of rods and rings (RR). These structures typically displayed rod lengths of 3-10μm and ring diameters of 2-5μm. Inosine monophosphate dehydrogenase (IMPDH) was identified as the primary component of the RR structures. Research on the administration of interferon/ribavirin (IFN/RBV) showed that ribavirin, an IMPDH inhibitor,

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