Academic literature on the topic '305.5/12'

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Journal articles on the topic "305.5/12"

1

Robbins, Brian L., Edmund V. Capparelli, Ellen G. Chadwick, et al. "Pharmacokinetics of High-Dose Lopinavir-Ritonavir with and without Saquinavir or Nonnucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus-Infected Pediatric and Adolescent Patients Previously Treated with Protease Inhibitors." Antimicrobial Agents and Chemotherapy 52, no. 9 (2008): 3276–83. http://dx.doi.org/10.1128/aac.00224-08.

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ABSTRACT Human immunodeficiency virus (HIV)-infected children and adolescents who are failing antiretrovirals may have a better virologic response when drug exposures are increased, using higher protease inhibitor doses or ritonavir boosting. We studied the pharmacokinetics and safety of high-dose lopinavir-ritonavir (LPV/r) in treatment-experienced patients, using an LPV/r dose of 400/100 mg/m2 orally every 12 h (p.o. q12h) (without nonnucleoside reverse transcriptase inhibitor [NNRTI]), or 480/120 mg/m2 p.o. q12h (with NNRTI). We calculated the LPV inhibitory quotient (IQ), and when the IQ w
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2

Shen, Cheng, Zhengguang Wu, Peng Xiao, Aihong Kang, and Yangbo Wang. "Experimental Research on the Anti-Reflection Crack Performance of Basalt Fiber Modified Rubber Asphalt Stress-Absorbing Layer." Materials 17, no. 9 (2024): 2013. http://dx.doi.org/10.3390/ma17092013.

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Reflection cracks are one of the most common problems in semi-rigid base pavement. Setting a stress absorption layer can effectively delay the occurrence of reflection cracks, but further improvement is still needed in its interlayer bonding performance and anti-reflection crack performance. Considering the excellent crack resistance of basalt fibers and the good elastic recovery ability of rubber asphalt, it is considered worthwhile to incorporate them into traditional stress absorption layers to improve performance. To simulate the actual pavement layer effect, composite specimens consisting
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3

Bridoux, Frank, Bertrand Arnulf, Lionel Karlin, et al. "Randomized Trial Comparing Double Versus Triple Bortezomib-Based Regimen in Patients With Multiple Myeloma and Acute Kidney Injury Due to Cast Nephropathy." Journal of Clinical Oncology 38, no. 23 (2020): 2647–57. http://dx.doi.org/10.1200/jco.20.00298.

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PURPOSE We report a multicenter controlled trial comparing renal recovery and tolerance profile of doublet versus triplet bortezomib-based regimens in patients with initial myeloma cast nephropathy (CN) and acute kidney injury (AKI) without need for dialysis. METHODS After symptomatic measures and high-dose dexamethasone, patients were randomly assigned to receive bortezomib plus dexamethasone (BD), or BD plus cyclophosphamide (C-BD). In patients with < 50% reduction of serum free light chains (sFLCs) after 3 cycles, chemotherapy was reinforced with either cyclophosphamide (BD group) or tha
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4

Jung, Kyung-Ho, Jin Hee Lee, Mina Kim, Young Seok Cho та Kyung-Han Lee. "89Zr Immuno-PET Imaging of Tumor PD-1 Reveals That PMA Upregulates Lymphoma PD-1 through NFκB and JNK Signaling". Molecular Imaging 2022 (12 лютого 2022): 1–13. http://dx.doi.org/10.1155/2022/5916692.

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Immune therapy of T-cell lymphoma requires assessment of tumor-expressed programmed cell death protein-1 (PD-1). Herein, we developed an immuno-PET technique that quantitatively images and monitors regulation of PD-1 expression on T-cell lymphomas. Methods. Anti-PD-1 IgG underwent sulfhydryl moiety-specific conjugation with maleimide-deferoxamine and 89Zr labeling. Binding assays and Western blotting were performed in EL4 murine T-cell lymphoma cells. In vivo pharmacokinetics, biodistribution, and PET were performed in mice. Results. 89Zr-PD-1 IgG binding to EL4 cells was completely blocked by
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5

EGWUE, Ogechi Lynda, Ikechi Kelechi AGBUGBA, and Ridwan MUKAILA. "ASSESSMENT OF RURAL HOUSEHOLDS FOOD INSECURITY DURING COVID-19 PANDEMIC IN SOUTH-EAST NIGERIA." International Journal of Research -GRANTHAALAYAH 8, no. 12 (2021): 182–94. http://dx.doi.org/10.29121/granthaalayah.v8.i12.2020.2713.

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The problem of food insecurity remains a challenge in developing countries, especially in rural areas. Despite the rising level of food insecurity, COVID-19 set in and was said to pose a threat to food security globally if adequate measures are not quickly put in place. This study, therefore, described the socio-economic characteristics of the respondents; examined the extent to which the rural households are food secure or otherwise during the COVID-19 pandemic and examine the drivers of food security status among rural households in South-East Nigeria. Primary data were collected from 200 ho
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6

Zou, Xianghui, Daniel King, Baho Sidiqi, Sunita Patruni, Christopher Hollweg, and Noah D. Kauff. "Socioeconomic disparities causing delays in pancreatic cancer germline genetic testing." Journal of Clinical Oncology 41, no. 4_suppl (2023): 665. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.665.

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665 Background: Germline genetic testing is recommended for patients with pancreatic ductal adenocarcinoma (PDAC) and pre-diagnostic testing is offered to patients with a significant family history. However, only 36% of patients in our institution obtained genetic testing. We identified associations between patient social profiles (income, race, ethnicity, social work needs) and delays in obtaining germline genetic testing from New York’s largest healthcare system. Methods: Patients with PDAC were identified using billing records across our institution with an IRB-approved protocol. Median inc
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7

Shi, X., and L. Pan. "AB0738 ELEVATED PLATELET COUNT IS A RISK FACTOR FOR REFRACTORY TAKAYASU ARTERITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1575.1–1575. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1197.

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BackgroundTakayasu arteritis (TAK) is a chronic systemic vasculitis that mainly affects the aorta and its major branches. This chronic relapsing disease is relevant to significant morbidity and treatment remains challenging [1]. Early identification of refractory TAK is helpful to improve the long-term prognosis of the disease. In recent years, platelets have been recognized as important markers for various types of diseases [2]. Platelet counts may indicate the activity of autoimmune disease as well as responsiveness to anti-inflammatory therapy and presence of various comorbidities [3]. Mult
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8

Kuhn, Deborah, Ping Wang, Irene Shu, Jie Xuan, Zheng Cao, and Barbara Savoldo. "Comparison of Free Light Chain Assay with Protein Electrophoresis for Screening and Monitoring PTLD." Blood 124, no. 21 (2014): 5883. http://dx.doi.org/10.1182/blood.v124.21.5883.5883.

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Abstract Background: Post-transplant lymphoproliferative disorder (PTLD) is primarily diagnosed histologically using tissue biopsy. Free light chain (FLC) assay and serum protein electrophoresis (SPE) have both been studied as tools to screen and monitor PTLD. However, limited data are available to compare these two assays in a well characterized patient population. It is also not clear what reference ranges should be adopted for the FLC assay in a post-transplant population. Method: Blood samples from 169 patients receiving a variety of solid organ transplants were analyzed for FLCs and scree
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9

Mathew, J., C. Kopp, S. K. Sharma, et al. "OP0240 A RANDOMIZED CONTROLLED TRIAL TO COMPARE THE EFFICACY OF TACROLIMUS WITH MYCOPHENOLATE MOFETIL IN PATIENTS WITH SYSTEMIC SCLEROSIS - INTERSTITIAL LUNG DISEASE (INSIST TRIAL)." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 160.1–160. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3107.

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BackgroundInterstitial lung disease in systemic sclerosis(SSc-ILD) is heterogeneous with limited therapeutic options. Mycophenolate mofetil (MMF) is the most commonly used first line agent for SSc-ILD. Tacrolimus has shown promising efficacy in few small case series, and large cohorts of patients with non-SSC-ILD[1], but has never been evaluated in the setting of a clinical trial.ObjectivesTo compare the safety and efficacy of Tacrolimus with MMF in patients with progressive SSc-ILD.MethodsIn this single center open labelled, prospective, two-arm parallel group, randomized controlled pilot stu
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10

Nakajima, Arata, Keiichiro Terayama, Masato Sonobe, et al. "Serum levels of reactive oxygen metabolites at 12 weeks during tocilizumab therapy are predictive of 52 weeks-disease activity score-remission in patients with rheumatoid arthritis." BMC Rheumatology 3, no. 1 (2019). http://dx.doi.org/10.1186/s41927-019-0096-1.

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Abstract Background To verify whether serum levels of reactive oxygen metabolites (ROM) are predictive of future clinical remission in patients with rheumatoid arthritis (RA) receiving tocilizumab (TCZ) therapy. Methods A total of 46 patients with RA receiving TCZ therapy were enrolled in this study. Patients were divided into remission and non-remission groups based on disease activity score 28 (DAS28)-erythrocyte sedimentation rate (ESR) or clinical disease activity index (CDAI) at 52 weeks. Associations between serum levels of ROM, C-reactive protein (CRP), and matrix metalloproteinase-3 (M
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Books on the topic "305.5/12"

1

Joe, Sacco, ed. Days of destruction, days of revolt. Nation Books, 2012.

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2

Aaron, Garrett, ed. The origin of the distinction of ranks, or, An inquiry into the circumstances which give rise to influence and authority, in the different members of society. Liberty Fund, 2006.

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3

Of good and ill repute: Gender and social control in medieval England. Oxford University Press, 1998.

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