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Journal articles on the topic '320/.01/1'

Author: Grafiati

Published: 25 July 2024

Last updated: 31 July 2025

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1

Bracken, J., C. Coolens, and B. Driscoll. "Sci-Sat AM(1): Planning - 01: Volumetric 4D Computed Tomography with a 320 Multi-Slice Scanner." Medical Physics 37, no. 7Part3 (2010): 3907. http://dx.doi.org/10.1118/1.3476201.

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รัตนะ, วัชระ, ละมัย ร่มเย็น та สัญญาศรณ์ สวัสดิ์ไธสง. "ปัจจัยที่ส่งผลต่อประสิทธิภาพการดำเนินงานกองทุนหมู่บ้านและชุมชนเมืองในเขตอำเภอวานรนิวาส จังหวัดสกลนคร". Interdisciplinary Academic and Research Journal 4, № 2 (2024): 507–28. http://dx.doi.org/10.60027/iarj.2024.274874.

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ภูมิหลังและวัตถุประสงค์: กองทุนหมู่บ้านมีวัตถุประสงค์เพื่อเป็นแหล่งเงินทุนหมุนเวียนสำหรับการลงทุนเพื่อพัฒนาอาชีพ สร้างงาน สร้างรายได้ เพิ่มรายได้และลดรายจ่าย หรือสำหรับการส่งเสริมและพัฒนาไปสู่การสร้างสวัสดิภาพ สวัสดิการ หรือประโยชน์ส่วนรวมอื่นใดให้แก่ประชาชนในหมู่บ้านหรือชุมชนเมือง รวมถึงเป็นแหล่งเงินทุนหมุนเวียนเพื่อบรรเทาความเดือดร้อนเร่งด่วนสำหรับประชาชนในหมู่บ้านหรือชุมชนเมือง ดังนั้นการวิจัยครั้งนี้มีวัตถุประสงค์เพื่อศึกษา (1) ระดับภาวะผู้นำเชิงกลยุทธ์ การมีส่วนร่วมของประชาชน และประสิทธิภาพการดำเนินงานกองทุนหมู่บ้านและชุมชนเมืองในเขตอำเภอวานรนิวาส (2) อิทธิพลของภาวะผู้นำเชิงกลยุทธ์ และการ

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Hawley, John A., Louise M. Burke, Damien J. Angus, Kieran E. Fallon, David T. Martin, and Mark A. Febbraio. "Effect of altering substrate availability on metabolism and performance during intense exercise." British Journal of Nutrition 84, no. 6 (2000): 829–38. http://dx.doi.org/10.1017/s0007114500002440.

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The purpose of this study was to determine the effect of altering substrate availability on metabolism and performance during intense cycling. Seven highly trained men ingested a random order of three isoenergetic meals 90 min before cycling at 80 % maximal oxygen uptake (VO2max) for 20 min (about 310 W), followed by a 600 kJ time trial lasting about 30 min. Meals consisted of either 1·2 g saturated fat/kg body mass (BM) with 3500 U heparin intravenously (HIFAT) to elevate circulating plasma free fatty acid (FA) concentration, 2·5 g carbohydrate/kg BM (CHO) to elevate plasma glucose and insuli

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Vučajnk, Filip, Valentina Spanic, Stanislav Trdan, Iztok Jože Košir, Miha Ocvirk, and Matej Vidrih. "Performance of Symmetric Double Flat Fan Nozzles against Fusarium Head Blight in Durum Wheat." Agriculture 14, no. 3 (2024): 343. http://dx.doi.org/10.3390/agriculture14030343.

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Four types of nozzles were tested on large-scale trials with a 40 m2 plot unit size. The Avi Twin 110-01 (80 L ha−1), 110-02 (160 L ha−1), 110-03 (240 L ha−1), and 110-04 (320 L ha−1) symmetric double fan injector nozzles were tested during the 2020/2021 and 2021/2022 growing seasons. This study aimed to evaluate the performance of spray nozzles with regard to deoxynivalenol (DON) accumulation in durum wheat grains. Artificial inoculation with Fusarium spp. was performed after durum heads were protected with fungicide. The percentage of heads covered with fungicide droplets, grain yield, yield

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Lynch, G. A., M. E. Hunt, and S. N. McCutcheon. "A note on the effect of monensin sodium administered by intraruminal controlled-release devices on productivity of dairy cows at pasture." Animal Science 51, no. 2 (1990): 418–21. http://dx.doi.org/10.1017/s0003356100005572.

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The effects of monensin sodium, administered by intraruminal controlled-release devices at a rate of 320 mglday, on milk and milk solids production and bloat score were examined in a trial with 90 lactating dairy cows given only mixed ryegrasslwhite clover pasture. Monensintreated cows had significantly greater yields of milk and milk protein than control cows (1397·2 (s.e. 22·9) v. 1296·9 (s.e. 16·3) kg milk, 49·6 (s.e. 0·9) v. 46·5 (s.e. 0·6) kg protein) over the 14-week period of treatment (P < 0·01). Yield of fat was similar in monensin-treated and control cows (62·9 (s.e. 1·5) v. 63·4

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Rondinone, Valeria, Lorenzo Pace, Antonio Fasanella, et al. "VOC 202012/01 Variant Is Effectively Neutralized by Antibodies Produced by Patients Infected before Its Diffusion in Italy." Viruses 13, no. 2 (2021): 276. http://dx.doi.org/10.3390/v13020276.

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The coronavirus disease 2019 (Covid-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presents a global health emergency that needs urgent intervention. Viruses constantly change through mutation, and new variants of a virus are expected to occur over time. In the United Kingdom (UK), a new variant called B.1.1.7 has emerged with an unusually large number of mutations. The aim of this study is to evaluate the level of protection of sera from 12 patients infected and later healed in Apulia Region (Italy) with Covid-19 between March and November 2020,

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Adaramoye, Toyin Olanike, Samuel Toyin Akanbi, and Tolulope Oluwatoyin Olayiwola-Adedoja. "INFLUENCE OF PATHOLOGICAL NARCISISM, INDECENT DRESSING AND LEARNED HELPLESSNESS ON SEXUAL HARASSMENT EXPERIENCE AMONG UNDERGRADUATE STUDENTS IN FEDERAL UNIVERSITY, OYE-EKITI, NIGERIA." Psikoislamedia : Jurnal Psikologi 9, no. 1 (2024): 1. http://dx.doi.org/10.22373/psikoislamedia.v9i1.21859.

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This study was conducted to examine the influence of pathological narcissism, indecent dressing, and learned helplessness on the experience of sexual harassment among students of the Federal University Oye-Ekiti, Nigeria. The study adopted the correlational research design and was guided by three research questions. It involved 284 undergraduate students between the ages of 16 and 21 who were selected through stratified random sampling using the stratum of faculty. Pathological Narcissism Inventory (α=.94), The Learned Helplessness Scale (α=.91) Indecent Dressing Measure (α=.90) and Sexual Har

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Delaney, Kerri Z., Leandra Spatari, Mélanie Henderson, Sylvia Santosa, and Marie-Eve Mathieu. "Substrate Oxidation Is Altered by Obesity During Submaximal Cycling in Prepubertal and Early Pubertal Children: A Quality Study." Pediatric Exercise Science 33, no. 1 (2021): 32–39. http://dx.doi.org/10.1123/pes.2020-0059.

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Background: To examine substrate oxidation in prepubertal and early pubertal children as a function of body weight, body composition, and sex during an exhaustive cycling test. Methods: This study included 320 children in prepubertal and early puberty (Tanner stage 1 or 2; n = 188 males) who completed a minimum of 4 stages (2–5 min/stage) of an adapted version of the McMaster exhaustive exercise protocol on an upright cycle ergometer. Substrate utilization, relative to individual VO2peak, was determined using VO2 and VCO2 data, obtained with breath-by-breath gas analysis during exercise. Resul

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Qiu, Chong-Rong, Qiang Fu, Jian Sui, et al. "Analysis of Serum Endothelial Cell-Specific Molecule 1 (Endocan) Level in Type 2 Diabetes Mellitus With Acute ST-Segment Elevation Myocardial Infarction and its Correlation." Angiology 68, no. 1 (2016): 74–78. http://dx.doi.org/10.1177/0003319716634581.

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Endothelial cell-specific molecule 1 (ESM-1; endocan) is expressed by endothelial cells, and it can be overexpressed in diabetic patients. However, little is known concerning diabetic patients with acute ST-segment elevation myocardial infarction (STEMI). Therefore, we assessed serum ESM-1 level in patients having type 2 diabetes mellitus (T2DM) STEMI; 72 patients with DM (38 with and 34 without vascular disease) and 33 individuals as a control group were included. There was a significant difference in serum ESM-1 level between the T2DM group and the control group ( P = .03). There was also a

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Zhao, Youshan, Feng Xu, Juan Guo, Sida Zhao, Chunkang Chang, and Xiao Li. "Dysregulation of ANKRD11 Influenced Hematopoisis By Histone Acetylation-Mediated Gene Expression in Myelodysplastic Syndrome." Blood 128, no. 22 (2016): 4292. http://dx.doi.org/10.1182/blood.v128.22.4292.4292.

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Abstract Background and Object In addition to histone deacetylation, the importance of histone over-acetylation induced oncogene transcription in initiation and progression of myelodysplastic syndrome (MDS) has been proposed recently. Our previous whole-exome sequencing identified a new somatic mutation, ANKRD11, an important factor in histone acetylation regulation. Its roles in MDS pathophysiology need to be clarified. Methods The next generation target sequencing (Including ANKRD11) was carried out in 320 patients with MDS using the MiSeq Benchtop Sequencer. ANKRD11 mRNA expression in bone

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Reza, Hajian, and Nazarpour Servak Maryam. "Multicomponent analysis of a ternary mixture of paracetamol, ibuprofen and caffeine in Novafen capsules with the aid of chemometrics." Journal of Indian Chemical Society Vol. 91, May 2014 (2014): 953–59. https://doi.org/10.5281/zenodo.5720251.

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Young researchers and Elite Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran <em>E-mail </em>: hajian@iaug.ac.ir Chemistry Department, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran <em>Manuscript received online 12 August 2013, revised 01 November 2013, accepted 01 November 2013</em> Net analyte signal standard addition method (NASSAM) has been presented for the simultaneous determination of paracetamol, ibuprofen and caffeine by spectrophotometry. The method combines the advantages of the standard addition method with the net analyte signal concept which enables t

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Bell, Hazel. "As I was saying: essays on the international book business by Gordon Graham London: Hans Zell. 320 pp, 1993. paperback £16.95. ISBN 1-873836-01-5." Learned Publishing 7, no. 1 (1994): 63–64. http://dx.doi.org/10.1002/leap/70015br1.

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Ndou, S. P., R. M. Gous, and M. Chimonyo. "Prediction of scaled feed intake in weaner pigs using physico-chemical properties of fibrous feeds." British Journal of Nutrition 110, no. 4 (2013): 774–80. http://dx.doi.org/10.1017/s0007114512005624.

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The objective of the present study was to predict scaled feed intake (SFI) using the physico-chemical measurements of feed bulk, such that gut capacity can be estimated in weaner pigs. A basal feed with 13·7 MJ digestible energy and 180 g crude protein per kg DM was diluted to six inclusion levels (0, 80, 160, 240, 320 and 400 g/kg DM) using lucerne hay, maize cob, maize stover, sawdust, sunflower husks or grass hay (veld grass). A total of 124 pigs weighing 18·1 (sd1·37) kg body weight were used. Water-holding capacity (WHC; g water/g DM), bulk density (g DM/ml), neutral-detergent fibre (NDF)

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LORD, EVELYN. "Blasphemers & Blackguards: The Irish Hellfire Clubs. By DAVID RYAN. Dublin: Merrion. 2012. 320 p. £40 (hb). ISBN 978-1-908928-03-0. £16.99 (pb). ISBN 978-1-908928-01-6." Journal for Eighteenth-Century Studies 36, no. 4 (2013): 594–95. http://dx.doi.org/10.1111/1754-0208.12026.

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Litvinova, Victoria R., Andrey P. Rudometov, Nadezhda B. Rudometova, et al. "DNA Vaccine Encoding a Modified Hemagglutinin Trimer of Avian Influenza A Virus H5N8 Protects Mice from Viral Challenge." Vaccines 12, no. 5 (2024): 538. http://dx.doi.org/10.3390/vaccines12050538.

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The development of a safe and effective vaccine against avian influenza A virus (AIV) H5N8 is relevant due to the widespread distribution of this virus in the bird population and the existing potential risk of human infection, which can lead to significant public health concerns. Here, we developed an experimental pVAX-H5 DNA vaccine encoding a modified trimer of AIV H5N8 hemagglutinin. Immunization of BALB/c mice with pVAX-H5 using jet injection elicited high titer antibody response (the average titer in ELISA was 1 × 105), and generated a high level of neutralizing antibodies against H5N8 an

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Razafindrainibe, Tanjonirina, Sidonie Rakotonomenjanahary, Mamitiana Andrianirina, and Nasolotsiry E. Ravel. "Congenital heart diseases and pregnancy, Universitary Hospital Center of Gynecology Obstetrical of Befelatanana, Madagascar." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 8 (2019): 3276. http://dx.doi.org/10.18203/2320-1770.ijrcog20193550.

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Background: Congenital heart diseases are malformations formed during the first weeks of life. Thanks to advances in medicine, they could be cared properly and pregnancies on heart diseases could be continued and completed. These malformations are sources of morbidity even high maternal fetal mortality. Whence our motivation to carry out this study and improve its care.Methods: This is a retrospective observational study reporting clinical cases of congenital heart disease pregnancies, only seen at the UHC-GOB over a seven years period (01 February 2007 - 28 February 2014).Results: We have ide

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Coberly, Jared, and Nitya Prabhakaran. "Evaluation of Forward Laser Light Scatter Technology as a Preculture Screen of Unpreserved Urine Specimens." American Journal of Clinical Pathology 152, Supplement_1 (2019): S133. http://dx.doi.org/10.1093/ajcp/aqz125.012.

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Abstract Introduction Urine cultures are standard of care for the diagnosis of urinary tract infections. Reflexively culturing specimens only after an effective screening test could minimize the number of samples cultured, improving laboratory efficiency. We evaluated a commercial forward laser light scatter system as a screening tool for urine cultures. Methods One hundred ninety (190) consecutive unpreserved urine specimens were screened by the BacterioScan 216Dx system (BacterioScan) prior to urine culture. Performance characteristics were compared against traditional culture methods. Resul

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Mahat, Hanifah, Muhammad Azizi Azri, Yazid Salleh, Nasir Nayan, and Mohamadisa Hashim. "The Use of Animated Elements to Increase Students’ Understanding in Geography Subjects." EDUCATUM Journal of Social Sciences 8, no. 2 (2022): 1–13. http://dx.doi.org/10.37134/ejoss.vol8.2.1.2022.

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This study aims to analyze the level, relationship, and contribution among the variables of readiness, motivation, interest, and attitude towards animated elements application in the subject of geography among Form 1, secondary school students in Jempol district, Negeri Sembilan. This study used a quantitative approach with a survey design and questionnaires. The sample of the study consisted of 320 first grade students selected by simple random sampling, while the selection of the school was done by stratified random sampling. Descriptive analyzes (mean, percentage) and inferential analyzes (

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Kuruoglu, Tuba, Levent Sensoy, Aynur Atilla, Fatih Temocin, Demet Gur, and Esra Tanyel. "Evaluation of risk factors for the development of bacteremia and complications in patients with brucellosis: Is it possible to predict the clinical course?" Journal of Infection in Developing Countries 17, no. 09 (2023): 1277–84. http://dx.doi.org/10.3855/jidc.18164.

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Introduction: Brucellosis is often confused with other diseases or accompanies the conditions it imitates. It causes treatment delays, failure, relapse, and complications. This study aimed to investigate bacteremia and complication predictors in Brucellosis patients. Early detection may help reduce relapse rates, length of hospital stay, and surgical intervention rates by providing appropriate treatment. Methodology: We examined 220 adult patients diagnosed with Brucellosis in our tertiary care hospital in the Black Sea Region between January 01, 2010, and January 01, 2022. Patients with and w

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Sinaga, Wulan Sari, Djoko Rahardjo, and Krismono Krismono. "Analisa Risiko Kesehatan Cemaran Krom dalam Beras di Kecamatan Jetis, Yogyakarta." Biospecies 16, no. 2 (2023): 27–33. http://dx.doi.org/10.22437/biospecies.v16i2.20205.

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The distribution of chromium originating from industrial waste disposal activities into the Opak River can pollute the flow of rice irrigation water which has an impact on food safety, especially rice. This study aims to determine the concentration of hexavalent chromium, the daily intake rate of age groups, and the effect of chromium on health risks. This research was conducted in Jetis District, Bantul, Yogyakarta with 3 sub-district locations: Canden Village, Trimulyo Village, and Sumber Agung Village. The research samples used were 60 rice samples from their own harvest using irrigation wa

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Faderl, Stefan, Meir Wetzler, David Rizzieri, et al. "Clofarabine Plus Cytarabine Compared With Cytarabine Alone in Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia: Results From the CLASSIC I Trial." Journal of Clinical Oncology 30, no. 20 (2012): 2492–99. http://dx.doi.org/10.1200/jco.2011.37.9743.

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Purpose To compare the receipt of clofarabine plus cytarabine (Clo+Ara-C arm) with cytarabine (Ara-C arm) in patients ≥ 55 years old with refractory or relapsed acute myelogenous leukemia (AML). Patients and Methods Patients were randomly assigned to receive either clofarabine (Clo) 40 mg/m2 or a placebo followed by Ara-C 1 g/m2 for five consecutive days. The primary end point was overall survival (OS). Secondary end points included event-free survival (EFS), 4-month EFS, overall remission rate (ORR; complete remission [CR] plus CR with incomplete peripheral blood count recovery), disease-free

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BELL, M. J., J. M. CLOY, C. F. E. TOPP, et al. "Quantifying N2O emissions from intensive grassland production: the role of synthetic fertilizer type, application rate, timing and nitrification inhibitors." Journal of Agricultural Science 154, no. 5 (2016): 812–27. http://dx.doi.org/10.1017/s0021859615000945.

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SUMMARYIncreasing recognition of the extent to which nitrous oxide (N2O) contributes to climate change has resulted in greater demand to improve quantification of N2O emissions, identify emission sources and suggest mitigation options. Agriculture is by far the largest source and grasslands, occupying c. 0·22 of European agricultural land, are a major land-use within this sector. The application of mineral fertilizers to optimize pasture yields is a major source of N2O and with increasing pressure to increase agricultural productivity, options to quantify and reduce emissions whilst maintainin

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Afzalunnessa, Sharmin Sultana, and Shahina Tabassum. "HLA gene polymorphism among Bangladeshi patients with end-stage renal disease awaiting kidney transplantation." Bangabandhu Sheikh Mujib Medical University Journal 15, no. 1 (2022): 1–10. http://dx.doi.org/10.3329/bsmmuj.v15i1.58420.

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Proper matching of HLA class I and class II antigens among donor and recipient is an important prerequisite for the long survival of a transplanted organ. To reveal the HLA gene polymorphism among end-stage renal disease (ESRD) patients and their donors, a total of 180 ESRD patients and 320 donors, referred by clinicians for HLA typing, were included in this study. HLA typing was performed using Polymerase Chain Reaction-Se- quence Specific Primer (PCR-SSP). The most frequent alleles reported from both groups were, A*11, A*02 and A*33 in A locus; B*15:02, B*35 and B*52 in B locus and DRB1*15,

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Tan, Boonfei, Xiaoli Dong, Christoph W. Sensen, and Julia Foght. "Metagenomic analysis of an anaerobic alkane-degrading microbial culture: potential hydrocarbon-activating pathways and inferred roles of community members." Genome 56, no. 10 (2013): 599–611. http://dx.doi.org/10.1139/gen-2013-0069.

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A microbial community (short-chain alkane-degrading culture, SCADC) enriched from an oil sands tailings pond was shown to degrade C6–C10 alkanes under methanogenic conditions. Total genomic DNA from SCADC was subjected to 454 pyrosequencing, Illumina paired-end sequencing, and 16S rRNA amplicon pyrotag sequencing; the latter revealed 320 operational taxonomic units at 5% distance. Metagenomic sequences were subjected to in-house quality control and co-assembly, yielding 984 086 contigs, and annotation using MG-Rast and IMG. Substantial nucleotide and protein recruitment to Methanosaeta concili

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Keiinbay, S., K. Kh Nussupov, A. T. Sultanov, I. E. Tyschenko, A. Ph Eshanov, and N. B. Beisenkhanov. "INFLUENCE OF THE RATIO OF GASE CONSUMPTION N<sub>2</sub> /AR AND MAGNETRON POWER ON THE DENSITY AND STOICHIOMETRIC COMPOSITION OF TIN<sub>X</sub> FILMS SYNTHESIZED BY MAGNETRON SPUTTERING METHOD." Herald of the Kazakh-British technical university 21, no. 3 (2024): 302–13. http://dx.doi.org/10.55452/1998-6688-2024-21-3-302-313.

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The films of titanium nitride were deposited by direct current magnetron sputtering on the surface of singlecrystalline silicon samples in an Ar-N2 atmosphere for use as a diffusion barrier. The thickness and density of films were measured by X-ray reflectometry. The design of the MAGNA TM-200-01 installation has been changed to increase the supply of nitrogen into the chamber. The influences of sputtering conditions, including the flow rate of nitrogen and argon gases and their N2 /Ar ratios in the range of 1–60 in the chamber, magnetron power of 690–1400 W on the formation of TiNx films, the

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MCCARTHY, JOHN P. "J. V. Fifer, The Master Builders: Structures of Empire in the New World, Spanish Initiatives and United States Invention (Durham: Durham Academic Press, 1996, £14.95). Pp. 320. ISBN 1 900838 01 X." Journal of American Studies 32, no. 3 (1998): 513–64. http://dx.doi.org/10.1017/s0021875898636033.

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MCCARTHY, JOHN P. "J. V. Fifer, The Master Builders: Structures of Empire in the New World, Spanish Initiatives and United States Invention (Durham: Durham Academic Press, 1996, £14.95). Pp. 320. ISBN 1 900838 01 X." Journal of American Studies 34, no. 2 (2000): 311–56. http://dx.doi.org/10.1017/s0021875899236419.

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Rudometov, Andrey P., Victoria R. Litvinova, Andrei S. Gudymo, et al. "Dose-Dependent Effect of DNA Vaccine pVAX-H5 Encoding a Modified Hemagglutinin of Influenza A (H5N8) and Its Cross-Reactivity Against A (H5N1) Influenza Viruses of Clade 2.3.4.4b." Viruses 17, no. 3 (2025): 330. https://doi.org/10.3390/v17030330.

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Highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b viruses are widespread in wild and domestic birds, causing severe economic damage to the global poultry industry. Moreover, viruses of this clade are known to cause infections in mammals, posing a potential pandemic threat. Due to the ongoing evolution and change in the dominant strains of H5 clade 2.3.4.4b, it is important to investigate the cross-reactivity of vaccines in use and under development against clade 2.3.4.4b viruses. In this study, the immunogenicity of the previously developed DNA vaccine encoding a modified hemagglutini

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Crabb, Simon J., Gareth Owen Griffiths, Ellice Marwood, et al. "ProCAID: A randomized double-blind phase II clinical trial of capivasertib (C) in combination with docetaxel and prednisolone chemotherapy (DP) in metastatic castration-resistant prostate cancer (mCRPC)." Journal of Clinical Oncology 38, no. 15_suppl (2020): 5520. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5520.

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5520 Background: DP extends survival in mCRPC, but clinical benefit is modest. PI3K/AKT/PTEN pathway activation is common in mCRPC contributing to disease progression and DP resistance. C is a pan-AKT inhibitor. Pre-clinical data indicate activity in prostate cancer and synergism with DP. This phase II trial combined C with DP in mCRPC. Methods: Key eligibility criteria: histologically or cytologically proven measurable or evaluable mCRPC, suitable for treatment with DP for PSA and/or radiographic disease progression, ECOG performance status 0-1, no prior chemotherapy for mCRPC, not requiring

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Silver, M., and A. L. Fowden. "Prepartum adrenocortical maturation in the fetal foal: responses to ACTH1–24." Journal of Endocrinology 142, no. 3 (1994): 417–25. http://dx.doi.org/10.1677/joe.0.1420417.

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Abstract The present study was carried out on 19 chronically catheterized mares and fetuses in late gestation (term >320 days). In six animals which were monitored up to the time of delivery of a live foal, plasma and amniotic fluid cortisol concentrations remained low until 4–5 days before parturition when there was a rapid, significant rise (P<0·05) which was not accompanied by any corresponding changes in maternal plasma cortisol. Circulating fetal ACTH concentrations became more variable close to delivery and ANOVA revealed no significant increases during this critical period, althou

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Grivas, Petros, Scott T. Tagawa, Joaquim Bellmunt, et al. "TROPiCS-04: Study of sacituzumab govitecan in metastatic or locally advanced unresectable urothelial cancer that has progressed after platinum and checkpoint inhibitor therapy." Journal of Clinical Oncology 39, no. 6_suppl (2021): TPS498. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.tps498.

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TPS498 Background: Treatment options are limited for patients with locally advanced unresectable or metastatic urothelial carcinoma (mUC) who progress following prior platinum-based and checkpoint inhibitor (CPI) therapy. Sacituzumab govitecan (SG) is an antibody-drug conjugate consisting of an anti–Trop-2 monoclonal antibody coupled to SN-38 (an active metabolite of irinotecan, a topoisomerase-I inhibitor) via a unique hydrolyzable linker. A phase II registrational study, TROPHY-U-01 study, confirmed the initial positive efficacy signal in mUC. SG demonstrated an objective response rate (ORR)

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Xue, Jinqi, Nan Niu, Shuo Wang, et al. "Neoadjuvant pyrotinib plus trastuzumab, dalpiciclib, and letrozole for triple-positive breast cancer: A pilot trial." Journal of Clinical Oncology 41, no. 16_suppl (2023): e12603-e12603. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e12603.

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e12603 Background: Our previous MUKDEN 01 study showed a promising total pathological complete response (tpCR) rate of 30.4% with neoadjuvant pyrotinib plus dalpiciclib (cyclin dependent kinase 4/6 inhibitor) and letrozole in patients with triple-positive breast cancer (TPBC), but the efficacy still needs improvement. This pilot study explored the efficacy and safety of adding trastuzumab to this neoadjuvant regimen in TPBC. Methods: Patients received five 28-day cycles of pyrotinib (320 mg once daily), dalpiciclib (125 mg once daily on days 1-21) and letrozole (2.5 mg once daily), plus six 21

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Welmer, Anna-Karin, Linda Sandberg, Christina Sandlund, et al. "Study protocol for the ‘preventing functional decline in acutely hospitalised older patients (PREV_FUNC)’ study: effects of two multicomponent exercise programmes on physical function – a three-armed randomised controlled trial." BMJ Open 13, no. 8 (2023): e070885. http://dx.doi.org/10.1136/bmjopen-2022-070885.

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IntroductionAcutely hospitalised older patients often live with frailty and have an increased risk of impaired physical function. Previous studies suggest that exercise might mitigate the risk of physical impairment; however, further research is needed to compare the effect of different types of exercise interventions. In this paper, we report a protocol for a trial that aims to examine (1) if multicomponent exercise interventions (interventions that include both mobility and strengthening exercises) have effects on physical function compared with usual care in older adults and (2) if a compre

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Verhoef, Sanne P. M., Diederick Meyer, and Klaas R. Westerterp. "Effects of oligofructose on appetite profile, glucagon-like peptide 1 and peptide YY3-36 concentrations and energy intake." British Journal of Nutrition 106, no. 11 (2011): 1757–62. http://dx.doi.org/10.1017/s0007114511002194.

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In rats, oligofructose has been shown to stimulate satiety hormone secretion, reduce energy intake and promote weight loss. The present study aimed to examine the effect of oligofructose supplementation on appetite profiles, satiety hormone concentrations and energy intake in human subjects. A total of thirty-one healthy subjects (ten men and twenty-one women) aged 28 (sem 3) years with a BMI of 24·8 (sem 0·3) kg/m2 were included in a randomised double-blind, cross-over study. The subjects received 10 g oligofructose, 16 g oligofructose or 16 g placebo (maltodextrin) daily for 13 d, with a 2-w

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Halim, Timotheus Y., Julye C. Lavoie, Michael J. Barnett, et al. "High Risk AML Outpatient Management: A Retrospective Analysis of Bacteremia Incidence Following Chemotherapy." Blood 104, no. 11 (2004): 884. http://dx.doi.org/10.1182/blood.v104.11.884.884.

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Abstract Treatment of acute myeloid leukemia (AML) involves aggressive remission inducing (IND) chemotherapy, and consolidation (CON) chemotherapy aimed at preventing or delaying relapse. Since September 2001, our institution has implemented a selective discharge protocol, which allows the majority of CON cycles, and some selected IND cycles, to be administered entirely on outpatient (OP), or early discharge (ED: prior to ANC >0.5 x 109/L or before d+15) basis. One of the primary concerns associated with this novel practice is the prompt management of infections in these high-risk neutropen

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Hartmane, Ilona, Ingmārs Mikažāns, Iveta Ivdra, Andra Dērveniece, and Ināra Ančupāne. "Experience of Phototherapy in Dermatological Praxis in Complex Therapy of Psoriasis Patients." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 70, no. 1 (2016): 7–12. http://dx.doi.org/10.1515/prolas-2016-0002.

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Abstract Psoriasis is a chronic relapsing skin disease presenting with erythematous and papulous lesions with infiltration and extensive desquamation on the skin surface. It is a genetically determined, multifactorial dermatosis where genetic, immune, and environmental factors play significant roles in its development. In Latvia in treatment of different forms of extensively spreading psoriasis, PUVA (psoralen and ultraviolet A light therapy), a combined method, is administered, applying long-wave UVA radiation with wavelength 320–400 nm in combination with photosensibilisator 8-metoxypsoralen

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Fang, Michele, Eric Hume, and Said Ibrahim. "Race, Bundled Payment Policy, and Discharge Destination After TKA: The Experience of an Urban Academic Hospital." Geriatric Orthopaedic Surgery & Rehabilitation 9 (January 1, 2018): 215145931880322. http://dx.doi.org/10.1177/2151459318803222.

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Background: Total knee arthroplasty (TKA) provides good clinical outcomes for the treatment of end-stage osteoarthritis; however, discharge destination after TKA has major implications on postoperative adverse outcomes and readmissions. With the initiation of Bundled Payments for Care Improvement (BPCI), it is unclear how racial disparities in discharge destination after TKA will be affected by the new bundled payment for TKA. Methods: Bundled Payments for Care Improvement was implemented in July 01, 2014, at the University of Pennsylvania. We compared differences during early implementation (

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Koenecke, Christian, Gudrun Göhring, Liesbeth de Wreede, et al. "Prognostic Value Of Five-Group Cytogenetic Risk Classification In Patients With MDS After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Multicenter Study Of The Chronic Malignancies Working Party Of The EBMT." Blood 122, no. 21 (2013): 2092. http://dx.doi.org/10.1182/blood.v122.21.2092.2092.

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Abstract Introduction The only curative treatment approach for patients with myelodysplastic syndromes (MDS) is allogeneic hematopoietic stem cell transplantation (HSCT), but disease relapse after transplantation is a major concern. Predictors for disease outcome after HSCT are limited. However, unfavorable cytogenetic abnormalities have been shown to serve as predictors for MDS-relapse after transplantation. Similar to the data available in MDS-patients not undergoing HSCT (Schanz et al. J Clin Oncol 2012), there is evidence that the novel 5-group cytogenetic classification has a better predi

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Martins Figueiredo, L., F. Correia, M. A. Rafael, et al. "P112 Impact of the SARS-COV2 pandemic on patients with inflammatory bowel disease - Preliminary results of a prospective, single-center study." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S204—S205. http://dx.doi.org/10.1093/ecco-jcc/jjab076.239.

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Abstract Background The real impact of COVID-19 infection on patients with Inflammatory Bowel Disease (IBD) is unknown. It was speculated that this population could be a risk group. The aim of this study is to evaluate the incidence of SARS-CoV2 infection, the impact of initiation/change of IBD therapy and its morbidity and mortality, during the COVID-19 pandemic in Portugal. Methods Prospective cross-sectional study. Patients with IBD followed at a Gastroenterology Department in an area with a high incidence rate of SARS-CoV2 were included, from 01/03/2020 to 31/08/2020. Data was obtained thr

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Egorov, Evgeny N., Nikolay I. Kol'tsov, and Nikolay F. Ushmarin. "TECHNOLOGICAL ADDITIVES FOR OIL AND PETROL RESISTANCE RUBBERS BASED ON BUTADIENE-NITRILE CAOUTCHOUCS." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 64, no. 6 (2021): 41–46. http://dx.doi.org/10.6060/ivkkt.20216406.6169.

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The article investigated the influence of various technological additives (zincolet BB 222, lubstab-01 and MA-L22) on the technological properties of the rubber mixture, physical, mechanical and operational characteristics of rubber based on nitrile butadiene caoutchouc BNKS-40AMN. Basic rubber mixture studied included caoutchouc, BC-FF percadox, zinc monomethacrylate, maleide F, triallyl isocyanurate, acetonanil N, MGF-9 and THM-3 oligoester acrylates, carbon black P 514 and other ingredients. The rubber mixture was prepared on laboratory rolls LB 320 160/160 in two stages. At the first stage

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Muñoz-Navarro, Roger, Virtudes Pérez-Jover, Gabriel Esteller-Collado, et al. "Protocol to evaluate the effectiveness of the implementation of transdiagnostic cognitive behavioural therapy for emotional disorders in primary care and its mechanisms of change: a randomized step-wedge clinical trial (PsicAP-CV)." PLOS ONE 20, no. 4 (2025): e0320857. https://doi.org/10.1371/journal.pone.0320857.

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Introduction Emotional disorders (ED) are highly prevalent worldwide. The PsicAP trial, conducted in Spain, demonstrated the benefits of adding transdiagnostic cognitive behavioural therapy (TD-CBT) to treatment as usual (TAU) for the attention of these disorders in primary care (PC). Here we describe the design of a stepped wedge randomized controlled trial (RCT), inspired by the PsicAP project. This RCT has two main aims: 1) to test the implementation of the PsicAP protocol in a real clinical setting, further evaluating possible mechanisms of change underlying the efficacy of TD-CBT (emotion

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Vardi, Anna, Andreas Agathangelidis, Evangelia Stalika, et al. "T Cell Receptor Gene Repertoire Restriction in Chronic Lymphocytic Leukemia with Stereotyped IGHV4–34/IGKV2–30 Antigen Receptors." Blood 120, no. 21 (2012): 3908. http://dx.doi.org/10.1182/blood.v120.21.3908.3908.

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Abstract Abstract 3908 Chronic lymphocytic leukemia (CLL) exhibits a remarkably skewed immunoglobulin (IG) gene repertoire mainly evident in the existence of subsets of patients with quasi-identical IGs in their B cell receptors (BcRs), collectively accounting for one-third of CLL patients. BcR stereotypy is strongly suggestive of clonal selection by a restricted set of antigens. However, it is not yet clear at which phase of clonal evolution these antigens act, or whether the stimulation is persistent. Furthermore, the possible role of antigens in the selection and activation of cognate T lym

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Hwang, Yung-Huyn, Young-Jin Lee, Seunghee Baek, et al. "Abstract P2-01-04: Impact of Mobile Healthcare Apps on Patient-Reported Quality of Life after Breast Cancer Surgery: A Randomized Controlled Trial." Clinical Cancer Research 31, no. 12_Supplement (2025): P2–01–04—P2–01–04. https://doi.org/10.1158/1557-3265.sabcs24-p2-01-04.

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Abstract Background: While numerous mobile healthcare applications (apps) have been developed, there remains a paucity of evidence regarding their efficacy in enhancing the quality of life for cancer patients. To bridge this gap, we conducted a randomized trial involving 320 breast cancer patients to evaluate the impact of utilizing apps postoperatively for six months on their overall well-being. Methods: Between November 2020 and September 2021, we enrolled stage 0-III breast cancer patients aged 20-60 who underwent surgery at Asan Medical Center. These participants were randomly assigned in

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DerSarkissian, Maral, Deepshekhar Gupta, Jasmina Ivanova, et al. "Racial differences in survival and healthcare resource utilization among Medicaid-insured adults with metastatic castration-resistant prostate cancer." Journal of Clinical Oncology 41, no. 6_suppl (2023): 29. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.29.

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29 Background: Prostate cancer (PC) disproportionately affects Black or African American (BAA) men in the United States (US), but racial disparities in outcomes are not well understood. This study analyzed racial disparities in OS, healthcare resource utilization (HRU), and PC treatments in Medicaid-insured metastatic castration resistant PC (mCRPC) patients. Methods: This retrospective longitudinal cohort study evaluated de-identified data from the Centers for Medicare and Medicaid Services 100% Medicaid data files from 01/01/2010 – 12/31/2018. The study included adult patients with a diagnos

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Blahova, Zuzana, Satoru Ikezawa, Peter Falkai, John H. Krystal, and Tarun Rangan. "CONNEX, a Phase III Randomized Trial Program Assessing Efficacy and Safety of Iclepertin in Schizophrenia: Recruitment and Baseline Characteristics." BJPsych Open 10, S1 (2024): S72—S73. http://dx.doi.org/10.1192/bjo.2024.230.

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AimsGlutamatergic signalling deficits contribute to the neuropathology of cognitive symptoms in schizophrenia. Iclepertin (BI 425809), a glycine transporter-1 inhibitor, enhances N-methyl-D-aspartate receptor signalling in the brain by increasing synaptic levels of its co-agonist glycine. The Phase III CONNEX programme aims to assess the efficacy, safety and tolerability of iclepertin in improving cognition and functioning in schizophrenia.MethodsCONNEX includes 3 randomised, double-blind, placebo-controlled parallel group trials in patients with schizophrenia from multiple centres across 41 c

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Knauer, Mark, Terry Armstrong, Brandon Barnes, et al. "254 Impact of Preweaning Factors on Nursery Throughput." Journal of Animal Science 100, Supplement_2 (2022): 119. http://dx.doi.org/10.1093/jas/skac064.201.

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Abstract The objective was to evaluate factors associated with nursery throughput. Data consisted of 3,260 piglets from 320 litters at the NCDA Tidewater Research Station. At weaning, piglets were housed nine per pen (0.23m2 per pig) in onsite nursery facilities for 35 d. Using linear models, farrowing batch (BATCH), gender, litter size (LS), average piglet birth weight (BWT), birth weight CV (BWT_CV), piglet weaning weight (WWT), weaning weight CV (WWT_CV) and weaning age (WEANAGE) were associated with nursery average daily gain (NurADG), nursery exit weight (NurEXITWT), nursery survival (SUR

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Al-Batran, Salah-Eddin, Ingeborg Roetzer, Luisa Wohn, et al. "Home parenteral nutrition (HPN) using individually compounded PN administered via multi-chamber Eurotubes versus PN administered via 2/3-chamber bags in patients with metastatic or localized solid tumors requiring HPN: The randomized IKF-010 PEKANNUSS trial of AIO." Journal of Clinical Oncology 41, no. 16_suppl (2023): e24123-e24123. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e24123.

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e24123 Background: Cancer patients (pts) often experience malnutrition and some of them require HPN. However, HPN is associated with challenges, including the need for nursing service to prepare PN bags and add supplements, severely limiting patient autonomy and flexibility. Moreover, HPN is a major risk factor for catheter-related infections (CRI). Eurotubes is a 7/8/9-multi-chamber system that offers fully individualized PN compounding without need for further line or bag manipulation outside GMP environment. This study evaluates whether HPN via Eurotubes improves patient autonomy compared w

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Hannan, Kellie Arensman, Paul Frykman, Eric Mathiowetz, Jill Sathre, Nou Cheng Yang, and Kelsey Jensen. "Reducing the rate of guideline-discordant therapy for inpatients with community-acquired pneumonia." Antimicrobial Stewardship & Healthcare Epidemiology 3, S2 (2023): s24. http://dx.doi.org/10.1017/ash.2023.244.

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Background: Despite guidelines recommending shorter durations of therapy and empiric coverage of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) only for patients with certain risk factors, optimizing therapy for community-acquired pneumonia (CAP) remains a challenge for antimicrobial stewardship (AMS) teams. We investigated the impact of a multimodal AMS initiative on the rate of guideline-discordant empiric antibiotic selection and total duration of therapy for CAP. Methods: A quality improvement initiative was implemented at 9 community hospitals in 2022 to opt

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Santoso, Rahmadius Eka, Amir Sjarifuddin Madjid, Rudyanto Sedono, and Maurin Marcelia. "Impact of neuromuscular electrical stimulation (NMES) on duration of mechanical ventilation in ICU patients: A systematic review and meta-analysis." Anaesthesia, Pain & Intensive Care 29, no. 1 (2025): 61–69. https://doi.org/10.35975/apic.v29i1.1887.

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Background: Intensive care unit acquired weakness (ICUAW) is associated with prolonged mechanical ventilation (PMV), increasing risk and mortality in intensive care unit (ICU) patients. Early mobilization along with neuromuscular electrical stimulation (NMES), has shown potential in reducing mechanical ventilation duration, but remains inconclusive. This study evaluates the impact NMES on the mechanical ventilation duration in ICU patients. Methodology: A systematic literature search was conducted using Cochrane, EBSCOhost, Scopus, and PubMed databases, employing specific keywords and Boolean

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Vulsteke, Christof, Petros Grivas, Scott T. Tagawa, et al. "TROPiCS-04: Study of sacituzumab govitecan (SG) in patients (pts) with locally advanced (LA) unresectable or metastatic urothelial cancer (mUC) that has progressed after prior platinum (PLT) and checkpoint inhibitor (CPI) therapy." Journal of Clinical Oncology 40, no. 6_suppl (2022): TPS582. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.tps582.

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TPS582 Background: Treatment options are limited for pts with LA unresectable or mUC who progress after prior PLT-based and CPI therapies. SG is an antibody-drug conjugate (ADC) composed of an anti-trophopblast cell surface antigen 2 (Trop-2) antibody coupled to SN-38 (a topoisomerase-I inhibitor) via a proprietary hydrolyzable linker. In the phase 2 registrational study TROPHY-U-01 (NCT03547973), SG demonstrated an objective response rate (ORR) of 27% and median overall survival (OS) of 10.9 months in pts with mUC who progressed after prior PLT-based and CPI therapies (n = 113; median, 3 prio

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