Academic literature on the topic '3208 Medical physiology'

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Journal articles on the topic "3208 Medical physiology"

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Ratti, Emiliangelo, David J. Carpenter, Stefano Zamuner, et al. "Efficacy of Vestipitant, A Neurokinin-1 Receptor Antagonist, in Primary Insomnia." Sleep 36, no. 12 (2013): 1823–30. http://dx.doi.org/10.5665/sleep.3208.

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Palve, Suchitra, and Sachin Palve. "Comparative study of self-directed learning and traditional teaching method in understanding cardio- respiratory physiology among medical undergraduates." Biomedicine 42, no. 1 (2022): 138–42. http://dx.doi.org/10.51248/.v42i1.662.

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Introduction and Aim: Active and learner centred learning methods specially, self-directed learning is considered to be an important method of blended learning approach of imparting knowledge among under graduate medical students in new curriculum through integrated approach. The aim of the study is to analyse the impact and benefits of self-directed learning sessions for understanding cardio- respiratory physiology among phase one MBBS students. Design and Methods: This cross-sectional study was conducted among 250 students of Phase I MBBS for CVS and RS modules. Two groups of students were m
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Zak, Margie B., Carl F. Dmuchowski, and Maureen A. Smythe. "Laboratory Abnormalities in Patients in the Medical Intensive Care Unit." Journal of Pharmacy Technology 12, no. 1 (1996): 12–15. http://dx.doi.org/10.1177/875512259601200105.

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Objective: The goals of this article are to (1) identify the incidence of reported laboratory abnormalities in patients in the medical intensive care unit (ICU); (2) characterize the relationship between reported laboratory abnormalities and Acute Physiology and Chronic Health Evaluation III (APACHE III) score, length of stay, and mortality; and (3) evaluate therapeutic replacement in patients with electrolyte abnormalities. Design: Retrospective chart review of all patients admitted to the medical ICU between April 1, 1993 and June 30, 1993. Setting: Large teaching institution. Participants:
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Boden, A. G., M. C. Harris, and M. J. Parkes. "Apneic threshold for CO2 in the anesthetized rat: fundamental properties under steady-state conditions." Journal of Applied Physiology 85, no. 3 (1998): 898–907. http://dx.doi.org/10.1152/jappl.1998.85.3.898.

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Experiments were performed to measure the apneic threshold for CO2 and its fundamental properties in anesthetized rats under steady-state conditions. Breathing was detected from diaphragmatic electromyogram activity. Mechanical hyperventilation resulted in apnea once arterial[Formula: see text]([Formula: see text]) had fallen far enough. Apnea was not a reflex response to lung inflation because it did not occur immediately, was not prevented by vagotomy, and was reversed by raising [Formula: see text]without changing mechanical hyperventilation. The apneic threshold was measured by hyperventil
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O'Connor, Sinéad, Paul McLoughlin, Charles G. Gallagher, and Helen R. Harty. "Ventilatory response to incremental and constant-workload exercise in the presence of a thoracic restriction." Journal of Applied Physiology 89, no. 6 (2000): 2179–86. http://dx.doi.org/10.1152/jappl.2000.89.6.2179.

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In the presence of an externally applied thoracic restriction, conflicting ventilatory responses to exercise have been reported, which could be accounted for by differences in exercise protocol. Seven male subjects performed two incremental and two constant-workload ergometer tests either unrestricted or in the presence of an inelastic corset. Ventilatory variables and arterial estimates of Pco 2 were obtained breath by breath. Subjects hyperventilated in the presence of restriction during the constant-workload test (38.4 ± 3.0 vs. 32.8 ± 3.0 l/min for the average of the last 3 min of exercise
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Scheuer, D. A., and M. H. Perrone. "Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 264, no. 5 (1993): R917—R923. http://dx.doi.org/10.1152/ajpregu.1993.264.5.r917.

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Angiotensin (ANG) can produce a biphasic arterial pressure response, i.e., an increase followed by a decrease. Because ANG type 1 (AT1) receptors mediate the pressor response to ANG, we hypothesized that the opposing depressor action is mediated by the ANG type 2 (AT2) receptors. In thiobutabarbital (Inactin)-anesthetized rats bolus injections of angiotensin III (ANG III; 100, 300, and 1,000 ng/kg iv) produced peak increases in MAP at 20 s of 13.4 +/- 1.4, 20.1 +/- 2, and 27.5 +/- 2.8 mmHg and maximum decreases in pressure at 120 s of -6.3 +/- 1.5, -6.8 +/- 2.2, and -11.4 +/- 4.9 mmHg. During
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Riedel, Thomas, John F. Fraser, Kimble Dunster, John Fitzgibbon, and Andreas Schibler. "Effect of smoke inhalation on viscoelastic properties and ventilation distribution in sheep." Journal of Applied Physiology 101, no. 3 (2006): 763–70. http://dx.doi.org/10.1152/japplphysiol.01635.2005.

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Smoke inhalation injuries are the leading cause of mortality from burn injury. Airway obstruction due to mucus plugging and bronchoconstriction can cause severe ventilation inhomogeneity and worsen hypoxia. Studies describing changes of viscoelastic characteristics of the lung after smoke inhalation are missing. We present results of a new smoke inhalation device in sheep and describe pathophysiological changes after smoke exposure. Fifteen female Merino ewes were anesthetized and intubated. Baseline data using electrical impedance tomography and multiple-breath inert-gas washout were obtained
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Koike, A., D. Weiler-Ravell, D. K. McKenzie, S. Zanconato, and K. Wasserman. "Evidence that the metabolic acidosis threshold is the anaerobic threshold." Journal of Applied Physiology 68, no. 6 (1990): 2521–26. http://dx.doi.org/10.1152/jappl.1990.68.6.2521.

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We evaluated maximal O2 uptake (VO2max), the metabolic acidosis threshold determined by the V-slope analysis [plot of CO2 output (VCO2) as a function of oxygen uptake (VO2)], the ratio of increase in VO2 to work rate increment (delta VO2/delta WR), the upper slope (S2) of the V-slope analysis, and the VO2 for work below and above the metabolic acidosis threshold to determine whether the changes in O2 transport caused by increased carboxyhemoglobin (HbCO) affected these parameters and variables. Ten normal subjects (aged 32.8 +/- 7.1 yr) performed symptom-limited incremental exercise tests in a
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Carolan, B., and E. Cafarelli. "Adaptations in coactivation after isometric resistance training." Journal of Applied Physiology 73, no. 3 (1992): 911–17. http://dx.doi.org/10.1152/jappl.1992.73.3.911.

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Twenty sedentary male university students were randomly assigned to an experimental or a control group. The experimental group trained the knee extensors of one leg by producing 30 isometric extension maximal voluntary contractions (MVC) per day, three times per week for 8 wk. After 8 wk of training, extensor MVC in the trained leg increased 32.8% (P less than 0.05), but there was no change in vastus lateralis maximal integrated electromyographic activity (IEMGmax). The most important finding was that the degree of hamstring coactivation during extension MVC decreased by approximately 20% (P l
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Masa, Juan F., Jaime Corral, Julio Sanchez de Cos, et al. "Effectiveness of Three Sleep Apnea Management Alternatives." Sleep 36, no. 12 (2013): 1799–807. http://dx.doi.org/10.5665/sleep.3204.

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Dissertations / Theses on the topic "3208 Medical physiology"

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Debruin, Danielle A. "A Pre-clinical Evaluation of Novel Combination Treatments to Alleviate Skeletal Muscle Loss and Dysfunction." Thesis, 2021. https://vuir.vu.edu.au/43472/.

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Preserving skeletal muscle mass is essential for maintaining optimal health throughout the lifespan. Altered skeletal muscle protein and energy metabolism, which typically occurs during the ageing process, leads to muscle degeneration, reduced strength and increased total body fat. As a result, the risk factor for chronic co-morbidities increases, highlighting the importance of preventing and/or treating decreased skeletal muscle mass and strength. While exercise, especially resistance training, is effective in slowing mass and strength loss, the search for appropriate drug therapies remains p
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Tacey, Alexander. "Uncovering the Interaction between Undercarboxylated Osteocalcin and Vascular Function in Normoglycaemic and Hyperglycaemic Environments." Thesis, 2020. https://vuir.vu.edu.au/42182/.

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Endothelial dysfunction is the initiating process in the development of atherosclerosis and cardiovascular disease (CVD) and is a significant predictor of future adverse cardiovascular events. Increasing evidence suggests a link between vascular function and the skeleton, an association that may be mediated by bone-derived proteins such as osteocalcin (OC). OC is an osteoblast-derived, vitamin K-dependent protein that primarily exists in two biological forms. Carboxylated osteocalcin (cOC) is involved in bone formation and undercarboxylated osteocalcin (ucOC) is suggested to be the bioactive f
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Campelj, Dean G. "Unravelling the mechanisms of chemotherapy-induced cachexia and the potential of mitoprotective therapeutic strategies." Thesis, 2021. https://vuir.vu.edu.au/42914/.

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Chemotherapy is an effective first-line cancer-treatment to slow or even cure cancer. Despite it being widely used to treat a variety of cancers, the majority of agents used induce a myriad of serious sequalae. Recently, chemotherapy emerged as a key contributing factor to the induction of devastating wasting condition, cachexia. Cachexia involves the progressive loss of body mass, underscored by severe skeletal muscle wasting and dysfunction (skeletal myopathy). Unravelling the molecular mechanisms involved in the onset and persistence of chemotherapy-induced cachexia represents a complex sci
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Conference papers on the topic "3208 Medical physiology"

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Zavrel, Erik A., and Ana C. Krieger. "An Inter-Device Accuracy Comparison of Consumer Sleep Trackers." In 2019 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/dmd2019-3205.

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The ability to investigate sleep is of scientific and clinical interest. Polysomnography (PSG) has long been considered the gold standard assessment for sleep physiology; however, its cost and inconvenience have spurred the development of consumer devices capable of evaluating sleep outside the laboratory. The development of dedicated consumer sleep monitoring devices, e.g., the Zeo Personal Sleep Manager, smart bands, e.g., the Microsoft Band 2 (MB2), and activity trackers, e.g., the Fitbit Charge 2 (FC2), with the ability to automatically distinguish between sleep and wakefulness has importa
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