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1

Rastogi, V. K., E. S. P. Bromfield, S. T. Whitwill, and L. R. Barran. "A cryptic plasmid of indigenous Rhizobium meliloti possesses reiterated nodC and nifE genes and undergoes DNA rearrangement." Canadian Journal of Microbiology 38, no. 6 (1992): 563–68. http://dx.doi.org/10.1139/m92-092.

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Indigenous Rhizobium meliloti were previously characterized on the basis of plasmid profiles and phage sensitivity patterns (phage types). Rhizobium meliloti 1076, which contained two cryptic plasmids, was one of four isolates comprising phage type 23. In this study, the large cryptic plasmid pVS1(size >500 b) was transferred from isolate 1076 into the plasmid-free strain of Agrobacterium tumefaciens UBAPF1. This plasmid contained nucleotide sequences homologous to genes for nodulation (nodB, nodC) and nitrogen fixation (nifH, nifD, nifK, nifE). Cosmid clones possessing the nod and nif homo
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2

Akamatsu, Takashi, Hideaki Moriyama, and Toshi Kaneda. "Genetic mapping of bfmA mutation causing fatty acid deficiency in Bacillus subtilis." Canadian Journal of Microbiology 39, no. 6 (1993): 629–33. http://dx.doi.org/10.1139/m93-091.

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Bacillus subtilis strain 626, defective in the bfmA gene, is a derivative of B. subtilis strain 168 and requires branched short-chain carboxylic acids for growth. Branched-chain 2-keto acid decarboxylase activity and fatty acid synthesis in B. subtilis strain 626 were 14 and 7%, respectively, of their levels in strain 626-2R, a spontaneously reverted strain. These results indicate that the bfmA mutation is in either the branched-chain 2-keto acid decarboxylase gene itself or its controlling gene. Thus, primer synthesis from the 2-keto acid substrate in strain 626 is defective, causing a defici
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3

Jyoti, Sharma, Ameta Rakshit, Kumar Sudhish, Ameta Noopur, Chanderia Kiran, and B. Punjabi Pinki. "Heterogeneous photo-Fenton degradation of mixture of Bismark brown-R and Azure-B dyes on copper loaded neutral alumina." Journal of Indian Chemical Society Vol. 89, Oct 2012 (2012): 1405–12. https://doi.org/10.5281/zenodo.5771320.

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Photochemistry Laboratory, Department of Chemistry, University College of Science, M. L. Sukhadia University, Udaipur-313 002, Rajasthan, India <em>E-mail</em> : pb_punjabi@yahoo.com Department of Physics, M. L Sukhadia University, Udaipur-313 002, Rajasthan, India <em>Manuscript received 09 November 2011, accepted OJ February 2012</em> In the present work, heterogeneous photo-Fenton degradation of mixture of two dyes has been investigated in aqueous medium under visible light. The selected two dyes are Bismark brown-R and Azure-B. The photocatalyst has been prepared by loading of Cu<sup>2+</s
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4

Guard, Hannah E., Michelle O. Sodipo, Colleen B. McGrath, et al. "Abstract 4935: Disentangling the association between age and overall survival in an international cohort of patients with advanced prostate cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 4935. https://doi.org/10.1158/1538-7445.am2025-4935.

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Abstract Introduction: Most people who die from prostate cancer are older than 75 years. However, prostate cancer diagnosed at younger ages is often more aggressive. While epidemiologic studies have examined the association between age and survival in patients with prostate cancer overall, the clinical drivers of this relationship in patients with advanced disease remain unclear. We leveraged the International Registry of Men with Advanced Prostate Cancer (IRONMAN, NCT03151629) to (1) quantify the association between age and overall survival and (2) explore whether this association is explaine
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5

Rakshit, Ameta, Ameta Chetna, Tak Paras, Benjamin Surbhi, Ameta Rameshwar, and C. Ameta Suresh. "Green chemistry : A step towards clean and sustainable development." Journal of Indian Chemical Society Vol. 89, Aug 2012 (2012): 999–1018. https://doi.org/10.5281/zenodo.5767140.

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Department of Chemistry, PAHER University, Udaipur-313 024, Rajasthan, India <em>E-mail</em> : ameta_sc@yahoo.com D Department of Chemistry, M. L. Sukhadia University, Udaipur-313 002, Rajasthan, India Department of Chemistry, Sunrise College of Engineering, Umarda, Udaipur-313 002, Rajasthan, India Department of Chemistry, S.M. B. Govt. College, Nathdwara-313 301, Rajasthan, India <em>Manuscript received 21 March 2012, accepted 23 March 2012</em>
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6

Wang, Kang, Zijing Jia, Linilin Bao, et al. "Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants." Nature 603, no. 7903 (2022): 919–25. http://dx.doi.org/10.1038/s41586-022-04466-x.

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AbstractOmicron (B.1.1.529), the most heavily mutated SARS-CoV-2 variant so far, is highly resistant to neutralizing antibodies, raising concerns about the effectiveness of antibody therapies and vaccines1,2. Here we examined whether sera from individuals who received two or three doses of inactivated SARS-CoV-2 vaccine could neutralize authentic Omicron. The seroconversion rates of neutralizing antibodies were 3.3% (2 out of 60) and 95% (57 out of 60) for individuals who had received 2 and 3 doses of vaccine, respectively. For recipients of three vaccine doses, the geometric mean neutralizati
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7

Hendrawan, Arya Ksatria Fernanda, Norma Afiati, and Arif Rahman. "Laju Nitrifikasi pada Bioremediasi Air Limbah Organik Menggunakan Chlorella sp. dan Bakteri Nitrifikasi-Denitrifikasi." Jurnal Pengelolaan Sumberdaya Alam dan Lingkungan (Journal of Natural Resources and Environmental Management) 11, no. 2 (2021): 309–23. http://dx.doi.org/10.29244/jpsl.11.2.309-323.

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Pencemaran nitrogen secara global begitu meningkat akibat pembuangan air limbah organik bersumber dari aktivitas manusia yang mencemari lingkungan perairan. Peningkatan senyawa nitrogen secara terus menerus dan dalam waktu yang lama menjadi penyebab terjadinya eutrofikasi dan kematian organisme. Proses reduksi nitrogen pada air limbah dapat dilakukan secara ekonomis dan efisien menggunakan bakteri nitrifikasi-denitrifikasi. Teknologi ramah lingkungan yang juga dapat digunakan adalah bioremediasi menggunakan mikroalga seperti Chlorella sp. Adanya hubungan sinergis dari bakteri dan mikroalga ber
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8

Whittall, Ian R., Mark G. Humphrey та David C. R. Hockless. "Structural Systematics of Metal Acetylide Complexes. II. X-Ray Studies of Some Nickel σ-Acetylide Complexes". Australian Journal of Chemistry 51, № 3 (1998): 219. http://dx.doi.org/10.1071/c97082.

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The structures of Ni(C≡CR)(PPh3)(η-C5H5) (R = Ph (1), C6H4-4-NO2 (2), 4-C6H4C6H4-4′-NO2 (3), (E)-4-C6H4CH=CHC6H4-4′-NO2 (4), 4-C6H4C≡CC6H4-4′-NO2 (5), 4-C6H4N=CHC6H4-4′-NO2 (6)) have been determined by single-crystal X-ray diffraction studies, refining by full-matrix least-squares analysis. For (1), crystals are triclinic, space group P-1, with a 10·094(2), b13·429(3), c 18·835(5) Å,α 103·24(2), β 91·50(2), γ 90·10(2)°, Z 4, 5844 unique reflections (595 parameters), converging at R 0·033 and Rw 0·024. For (2), crystals are orthorhombic, space group Pna21, with a 16·799(2), b 8·681(2), c 17·485
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9

Xu, Junfeng, Feng Liu, and Bo Dang. "Phase Selection in Undercooled Ni-3.3 Wt Pct B Alloy Melt." Metallurgical and Materials Transactions A 44, no. 3 (2012): 1401–8. http://dx.doi.org/10.1007/s11661-012-1496-7.

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10

Naveen, Mittal, Shah Arti, Bhati Indu, B. Punjabi Pinki, and K. Sharma V. "Photocatalytic bleaching of malachite green by manganese dioxide." Journal of Indian Chemical Society Vol. 88, May 2011 (2011): 673–75. https://doi.org/10.5281/zenodo.5769051.

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Department of Chemistry, Govt. J. D. B. Girls College, Kota-324 001, Rajasthan, India Department of Chemistry, College of Science, Mohan Lal Sukhadia University, Udaipur-313 002, Rajasthan, India <em>E-mail</em> : pb_punjabi@yahoo.com <em>Manuscript received 05 May 2009, revised 26 August 2010, accepted 31 August 2010</em> The photocatalytic bleaching of aqueous solution of malachite green using manganese dioxide as photocatalyst has been carried out. The absorbance of reaction mixture at different time intervals has been observed spectrophotometrically. The effect of variation of different pa
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11

Bongmo, Laurent Voufack Lefack, Achille Bissoue Nouga, Gervais Mouthé Happi та ін. "Phytochemical compounds of <i>Guibourtia ehie</i> and their antioxidant, urease and α-glucosidase inhibitory activities". Natural Resources for Human Health 2, № 3 (2022): 306–12. http://dx.doi.org/10.53365/nrfhh/145341.

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Thirteen compounds (&lt;b&gt;1&lt;/b&gt;‒&lt;b&gt;13&lt;/b&gt;) were isolated and identified during phytochemical analysis of the leaves and stem bark of &lt;i&gt;Guibourtia ehie&lt;/i&gt; (A. Chev) J. Leonard. Spectroscopic and spectrometric methods and the comparison of their results with those given in the literature were used to ascertain their structures. Furthermore, the acetylation of 3,3′-di-&lt;i&gt;O&lt;/i&gt;-methylellagic acid 4′-&lt;i&gt;O&lt;/i&gt;-β-D-xylopyranoside (&lt;b&gt;2&lt;/b&gt;) afforded a new derivative 3,3′-di-&lt;i&gt;O&lt;/i&gt;-methylellagic acid 4′-&lt;i&gt;O&lt;
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12

Parmar, Kanak, Sai Subramanyam, Duke Appiah, and Sarbajit Mukherjee. "Ant-PD-1/PD-L1 inhibitors in metastatic gastroesophageal cancers (GEC): A systematic review and meta-analysis." Journal of Clinical Oncology 40, no. 4_suppl (2022): 323. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.323.

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323 Background: CheckMate 649 and KEYNOTE 590 studies established the role of immune checkpoint inhibitors (ICI) in the frontline setting for unresectable, advanced, or metastatic GEC. However, many GEC patients do not benefit from ICI. The purpose of the study was to evaluate the efficacy of ICI in various subgroups of GEC patients. Methods: We searched MEDLINE/PubMed, Embase, ESMO, and ASCO Meeting Abstracts for phase II or III randomized clinical trials (RCTs) testing ICI in metastatic/advanced gastric or gastroesophageal junction or esophageal cancer. Outcome measures included overall surv
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13

YATSUHASHI, H. "P-313 Interferon ? and ? combination therapy for chronic hepatitis C." International Hepatology Communications 3 (July 1995): S115. http://dx.doi.org/10.1016/0928-4346(95)90609-b.

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14

M. Alabdallah, Nadiyah, Md Mahadi Hasan, Abdalrhaman M. Salih, et al. "Silver nanoparticles improve growth and protect against oxidative damage in eggplant seedlings under drought stress." Plant, Soil and Environment 67, No. 11 (2021): 617–24. http://dx.doi.org/10.17221/323/2021-pse.

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Drought stress is a significant abiotic stressor that has a negative impact on crop production and global food security systems. Drought stress was applied to eggplant seedlings with various field capacities (FC), 80% FC as control, 50% FC, 35% FC, and 20% FC. AgNPs were synthesised from green chemical methods, whereas different concentrations of AgNPs (0, 0.1, 0.2, 0.5 µmol) were applied exogenously on drought-stressed eggplants. Drought stress decreased the growth parameters (plant height, fresh mass, dry mass, leaf area), photosynthetic pigments (Chl a, Chl b, carotenoids), and protein cont
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15

Mumtaz, Samina, Shagufta Tabassum, and Saima Afzal. "Early versus delayed cord clamping in term neonates." Professional Medical Journal 28, no. 05 (2021): 656–60. http://dx.doi.org/10.29309/tpmj/2021.28.05.4578.

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Objective: To compare mean hemoglobin levels of neonates after early and late cord clamping. Study Design: Randomized Controlled Trial. Setting: Department of Obstetrics &amp; Gynaecology at Nishtar Hospital Multan. Period: June 2019 to December 2019. Material &amp; Methods: A total of 60 women booked and unbooked were included in study. Selected patients randomized into group A and B, each group comprising of 30 patients depending upon the envelope with assigned treatment (either early or delayed cord clamping) picked up by the patient. Results: In present study, two groups were made. Group A
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16

Maximova, M. Yu, and E. T. Suanova. "Pain and sensory disorders after removal of mandibular third molars." Meditsinskiy sovet = Medical Council, no. 12 (August 14, 2024): 96–100. http://dx.doi.org/10.21518/ms2024-326.

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Introduction. Extraction of mandibular third molars is one of the most common oral surgical procedures.Aim. To evaluate the efficacy of B Complex Preparation on pain and sensory problems related to inferior alveolar nerve damage after surgical removal of mandibular third molars.Materials and methods. In the open-label comparative trial 86 patients aged 45 to 54 years with sensory disturbances, lasting 72 hours, after surgical removal of mandibular third molar were included. Pain intensity was assessed using a visual analogue scale (VAS). Quantitative sensory testing (QST) was performed with th
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17

Cooley, Sarah, Daniel J. Weisdorf, Lisbeth A. Guethlein, et al. "Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia." Blood 116, no. 14 (2010): 2411–19. http://dx.doi.org/10.1182/blood-2010-05-283051.

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AbstractKiller-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system. Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-content motifs. Aiming to develop a donor selection strategy to improve transplant outcome, we compared the contribution of these motifs to the clinical benefit conferred by B haplotype donors. We KIR genotyped donors from 1409 unrelated transplants for acute myelogenous leukemia (AML; n = 1086) and acute lymphoblastic leukemia (ALL; n = 323). Donor KIR genotype influenced transplantation outcome for AML but
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18

Lee, J. S. "Lymph pressure in rat intestinal lymph duct with lymphatic obstruction." American Journal of Physiology-Gastrointestinal and Liver Physiology 251, no. 3 (1986): G321—G325. http://dx.doi.org/10.1152/ajpgi.1986.251.3.g321.

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Lymph pressure (PL) in the main intestinal lymph duct with obstruction of lymph flow was determined. Under various conditions, the rate of lymph flow (JL) was essentially the same in either A rats (with communications between hepatic and intestinal lymphatics) or B rats (without such communications), but PL of A rats was significantly lower (P less than 0.01) than that of B rats. When the intestine was in the basal state, JL of A and B rats was 0.2-0.3 ml/h per rat, and PL was 1.5 +/- 0.2 and 3.3 +/- 0.2 mm/Hg, respectively. During fluid absorption, JL of A and B rats increased to 0.8-0.9 ml/h
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19

Krug, S., I. Portig, D. Librizzi, A. Pfestroff, T. Gress, and P. Michl. "B-Symptomatik und Kauclaudicatio bei einem 79-jährigen Patienten." Der Internist 54, no. 2 (2013): 249–53. http://dx.doi.org/10.1007/s00108-012-3223-2.

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20

Zaksas, Natalia P., Svetlana E. Soboleva, and Georgy A. Nevinsky. "Twenty Element Concentrations in Human Organs Determined by Two-Jet Plasma Atomic Emission Spectrometry." Scientific World Journal 2019 (October 24, 2019): 1–9. http://dx.doi.org/10.1155/2019/9782635.

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In this paper, we have performed determination of the concentration of twenty elements in seven human organs (spleen, liver, kidney, muscle, heart, lungs, and brain) using two-jet plasma atomic emission spectrometry. The method allows multielemental analysis of solid samples without wet acid digestion. Before analysis, all human organs were first dried, ground to powders, and carbonized. The relative content of elements in each of the seven organs was very different depending on the donor. The average content of twenty elements in various organs varied in the following ranges (μg/g of dry weig
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Dzubiel, Darinka, Heiko Ihmels, Mohamed M. A. Mahmoud, and Laura Thomas. "A comparative study of the interactions of cationic hetarenes with quadruplex-DNA forming oligonucleotide sequences of the insulin-linked polymorphic region (ILPR)." Beilstein Journal of Organic Chemistry 10 (December 11, 2014): 2963–74. http://dx.doi.org/10.3762/bjoc.10.314.

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The interactions of the ILPR sequence (ILPR = "insulin-linked polymorphic region") a2 [d(ACAG4TGTG4ACAG4TGTG4)] with [2.2.2]heptamethinecyanine derivatives 1a–e and with the already established quadruplex ligands coralyne (2), 3,3′-[2,6-pyridinediylbis(carbonylimino)]bis[1-methylquinolinium] (3), 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methylpyridinium] (4), naphtho[2,1-b:3,4-b′:6,5-b′′:7,8-b′′′]tetraquinolizinium (5) and thiazole orange (6) were studied. It is demonstrated with absorption, fluorescence and CD spectroscopy that all investigated ligands bind with relativel
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22

Byrd, Kathy K., John T. Redd, Robert C. Holman, Dana L. Haberling, and James E. Cheek. "Changing Trends in Viral Hepatitis-Associated Hospitalizations in the American Indian/Alaska Native Population, 1995–2007." Public Health Reports 126, no. 6 (2011): 816–25. http://dx.doi.org/10.1177/003335491112600607.

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Objective. We described the changing epidemiology of viral hepatitis among the American Indian/Alaska Native (AI/AN) population that uses Indian Health Service (IHS) health care. Methods. We used hospital discharge data from the IHS National Patient Information Reporting System to determine rates of hepatitis A-, B-, and C-associated hospitalization among AI/ANs using IHS health care from 1995–2007 and summary periods 1995–1997 and 2005–2007. Results. Hepatitis A-associated hospitalization rates among AI/AN people decreased from 4.9 per 100,000 population during 1995–1997 to 0.8 per 100,000 po
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23

Blum, Joanne L., Patrick J. Flynn, Greg Yothers, et al. "Anthracyclines in Early Breast Cancer: The ABC Trials—USOR 06-090, NSABP B-46-I/USOR 07132, and NSABP B-49 (NRG Oncology)." Journal of Clinical Oncology 35, no. 23 (2017): 2647–55. http://dx.doi.org/10.1200/jco.2016.71.4147.

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Purpose Docetaxel and cyclophosphamide (TC) was superior to doxorubicin and cyclophosphamide (AC) in a trial in early breast cancer. However, activity of TC relative to AC regimens with a taxane (TaxAC) is unknown. Methods In a series of three adjuvant trials, women were randomly assigned to TC for six cycles (TC6) or to a standard TaxAC regimen. US Oncology Research (USOR) 06-090 compared TC6 with docetaxel, doxorubicin, and cyclophosphamide (TAC6). National Surgical Adjuvant Breast and Bowel Project (NSABP) B-46-I/USOR 07132 compared TC6, TAC6, or TC6 plus bevacizumab. NSABP B-49 compared TC
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24

Kim, S., M. Hiruma, F. Ikemoto, and K. Yamamoto. "Importance of glycosylation for hepatic clearance of renal renin." American Journal of Physiology-Endocrinology and Metabolism 255, no. 5 (1988): E642—E651. http://dx.doi.org/10.1152/ajpendo.1988.255.5.e642.

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Three differently glycosylated forms of renin (renin A, B-1, and B-2) were highly purified from rat kidneys by pepstatin-aminohexyl-Sepharose affinity chromatography and by serial lectin affinity chromatography on concanavalin A (con A) and lentil lectin-Sepharose, and the role of glycosylation of renin was investigated. Renin A and renin B-1 were loosely and tightly bound to con A, respectively, but did not bind to lentil lectin. Renin B-2 bound to both con A and lentil lectin. These three forms of renin were all similar in their physicochemical characteristics, including molecular weight, is
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25

Martini, Alberto, Claudia Kesch, Alae Touzani, et al. "Personalized Mobile App–Based Program for Preparation and Recovery After Radical Prostatectomy: Initial Evidence for Improved Outcomes From a Prospective Nonrandomized Study." Journal of Medical Internet Research 26 (December 13, 2024): e55429. https://doi.org/10.2196/55429.

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Background eHealth can help replicate the benefits of conventional surgical prehabilitation programs and overcome organizational constraints related to human resources and health care–related costs. Objective We aimed to assess the impact of an optimized perioperative program using a personalized mobile app designed for preparation and recovery after radical prostatectomy (RP). Methods We report on a series of 122 consecutive robot-assisted RP before and after the implementation of the betty.care app (cohort A: standard of care, n=60; cohort B: optimized program, n=62). The primary end point w
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26

Wang, Wen, Linghua Wang, Säm Krucker, and Robert F. Wimmer-Schweingruber. "Energy Spectrum of Solar Energetic Electron Events over 25 Years." Astrophysical Journal 948, no. 1 (2023): 51. http://dx.doi.org/10.3847/1538-4357/acbea2.

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Abstract We investigate the peak flux energy spectrum of 458 solar energetic electron (SEE) events with a clear velocity dispersion detected at energies from ≤4.2 to ≥108 keV by Wind/3DP from 1994 December through 2019 December, utilizing a pan-spectrum fitting method. According to the fitted spectral parameters, these 458 events are self-consistently classified into five spectral types: 304 downward double-power-law (DDPL) events, 32 upward double-power-law (UDPL) events, 23 single-power-law (SPL) events, 44 Ellison–Ramaty (ER) events, and 55 logarithmic–parabola (LP) events. The DDPL events
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27

Gerner, P., Andre Hörning, S. Kathemann, K. Willuweit, and S. Wirth. "Growth Abnormalities in Children with Chronic Hepatitis B or C." Advances in Virology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/670316.

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Background. It has been suggested that chronic hepatitis B infection leads to growth impairment, but data are inconsistent and underlying factors are not defined.Methods. Children and adolescents with chronic hepatitis B (HBV) or C (HCV) were retrospectively evaluated for growth, weight, antiviral treatment, biochemical signs of liver inflammation, route of infection, and HBV DNA, respectively.Results. In all, 135 children (mean age 6.1 years, 81 male, 54 female) with HBV (n=78) or HCV (n=57) were studied. Route of infection was vertical in 50%, parenteral in 11%, and unknown in 39%. ALT level
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28

Hsu, Chih-Yu, Liang-Sien Chen, I.-Jen Chang, et al. "Can Anthropometry and Body Composition Explain Physical Fitness Levels in School-Aged Children?" Children 8, no. 6 (2021): 460. http://dx.doi.org/10.3390/children8060460.

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Physical fitness (PF) is closely related to various health outcomes and quality of life among children. However, the associations between anthropometry, body composition (BC), and PF are not fully elucidated. This cross-sectional study aimed to investigate the associations between demographic metrics (age, sex), anthropometric measures (body mass index z-score (BMI z-score) waist/height ratio (WHtR)), BC parameters (body-fat percentage (BF%), muscle weight), and PF levels (800-m run, sit-and-reach, 1-min sit-ups, standing long jump) in school-aged children. Continuous variables were dichotomiz
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CH, TARIQ HASSAN, ASGHAR ALI, and MUNAWAR JAMIL. "ACUTE CHOLECYSTITIS." Professional Medical Journal 17, no. 02 (2010): 185–92. http://dx.doi.org/10.29309/tpmj/2010.17.02.2342.

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Introduction: Gallstones are common biliary pathology. The Vast majority of subjects are asymptomatic. About 0.2% of the population suffering from gallstones develop acute cholecystitis every year. In case of acute calculous cholecystitis, cholecystectomy can be performed early i.e during the same admission or interval i.e after 6 weeks of conservative management. Objective: To compare the early and interval cholecystectomy in acute calculous cholecystitis for morbidity, postoperative hospital stay, total hospital stay and complications. Study Design: Quasi-experimental study. Setting: Departm
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CH, TARIQ HASSAN, and ASGHAR ALI. "ACUTE CHOLECYSTITIS." Professional Medical Journal 17, no. 02 (2018): 185–92. http://dx.doi.org/10.29309/tpmj/2010.17.02.2218.

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Introduction: Gallstones are common biliary pathology. The Vast majority of subjects are asymptomatic. About 0.2% of the population suffering from gallstones develop acute cholecystitis every year. In case of acute calculous cholecystitis, cholecystectomy can be performed early i.e during the same admission or interval i.e after 6 weeks of conservative management. Objective: To compare the early and interval cholecystectomy in acute calculous cholecystitis for morbidity, postoperative hospital stay, total hospital stay and complications. Study Design: Quasi-experimental study. Setting: Departm
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31

Bigun, Inna, and Yaroslav M. Kalychak. "The Crystal Structure of GdZn3." Zeitschrift für Naturforschung B 68, no. 11 (2013): 1265–68. http://dx.doi.org/10.5560/znb.2013-3182.

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The crystal structure of GdZn3 was refined using singlecrystal X-ray diffraction data: YZn3 type, space group Pnma, Z = 4, a = 6:7250(13), b = 4:4620(9), c = 10:201(2) Å , R1 = 0:049, wR2 = 0:082, 303 F2 values, 25 variables. The zinc atoms build up a three-dimensional network with short Zn-Zn distances, while the Gd atoms are well separated from each other. The coordination number is 17 for Gd, and 10 and 12 for the Zn atoms.
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32

Engering, Josef, Eva-Maria Peters, and Martin Jansen. "Synthesen und Kristallstrukturen von Bis(N-lithiumtrimethylsilylamino)- bis(dimethylamino)silan und 1,1-Dichloro-2,4-bis(trimethylsilylamino)- 3,3-bis(dimethylamino)siladiazatitanacyclobutan / Syntheses and Crystal Structures of Bis(N-lithio-trimethylsilylamino)bis(dimethylamino)- silane and 1,1-Dichloro-2,4-bis(trimethylsilylamino)-3,3-bis(dimethylamino)siladiazatitanacyclobutane." Zeitschrift für Naturforschung B 57, no. 9 (2002): 976–82. http://dx.doi.org/10.1515/znb-2002-0902.

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Bis(N-lithio-trimethylsilylamino)bis(dimethylamino)silane (1) is formed in the reaction of silicon tetrachloride with excess hexamethyldisilazane, followed by halogen substitution using two equivalents of LiN(CH3)2, and treatment with two equivalents of n-butyllithium in hexane. 1, found to be dimeric in the solid state, was characterised by single crystal X-ray diffraction (monoclinic, C2/c, a = 1925.2(4), b = 1501.7(2), c = 1389.7(3) pm, β= 101.98(2), Z = 4, C20H60Li4N8Si6), and by solid state and solution NMR spectroscopy and mass spectrometry. Further reaction with titanium tetrachloride (
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33

Alferiev, Ivan S., and Sergey Yu Bobkov. "Cyclic Oligophosphonic Anhydrides Stable in Aqueous Media." Zeitschrift für Naturforschung B 47, no. 9 (1992): 1213–24. http://dx.doi.org/10.1515/znb-1992-0902.

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Depending on reaction conditions, the phosphonylation of N-alkylacetamides with H3PO3– PCl3 in B · HCl media (B = Py, Bu3N) gives either 1-alkylaminoethylidene-1,1-bisphosphonic acids (la–e) or previously unknown 1-alkylaminobutane-1,1,3,3-tetrayl-tetrakisphosphonic dianhydrides (2a–e). The latter convert into monocyclic forms (3a–e) under mild acidic hydrolysis. Acyclic forms (4a–e) cannot be isolated. In the presence of higher N,N-dialkylamides the phosphonylation of acetamides affords the higher dianhydrides (2f–h). Strong acidic hydrolysis of 2 or 3 yields 3,3-diphosphonocarboxylic acids (
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34

Soedarman, Soefiandi, Madarina Julia, Tjahjono D. Gondhowiardjo, Alberthus Donni Budi Prasetya, King Hans Kurnia, and Muhammad Bayu Sasongko. "Serum apolipoprotein A1 and B are associated with 6-month persistent and incident diabetic macular oedema in type 2 diabetes." BMJ Open Ophthalmology 8, no. 1 (2023): e001207. http://dx.doi.org/10.1136/bmjophth-2022-001207.

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AimsTo investigate the associations of baseline apolipoprotein A1 (ApoA1) and B (ApoB) levels with persistent and incident diabetic macular oedema (DMO) after 6 months of follow-up.MethodsThis is a prospective cohort study of patients aged ≥30 years with untreated diabetic retinopathy. Examinations, fundus photography and spectral domain optical coherence tomography (SD-OCT) were assessed at baseline, 1, 3 and 6 months. Serum lipids and apolipoproteins were analysed at a pathology laboratory. DMO was confirmed using SD-OCT, classified as (1) incident DMO, (2) persistent DMO and (3) regressed D
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35

Muluk, Nizamul, Agung Warsito, and Juningtyastuti Juningtyastuti. "SIMULASI PEMULIHAN KEDIP TEGANGAN AKIBAT GANGGUAN ARUS HUBUNG SINGKAT MENGGUNAKAN DYNAMIC VOLTAGE RESTORER (DVR)." TRANSIENT 6, no. 3 (2017): 316. http://dx.doi.org/10.14710/transient.6.3.316-322.

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Masalah kualitas daya listrik merupakan masalah utama pada sistem tenaga listrik yang harus diatasi, salah satu permasalahan kualitas daya listrik adalah kedip tegangan, yang dapat disebabkan salah satunya oleh gangguan arus hubung singkat. Kedip tegangan dapat menyebabkan tegangan turun dalam waktu singkat dan menyebabkan daya aktif dan daya reaktif mengalami perubahan nilai. Untuk mengatasi terjadinya kedip tegangan, diperlukan alat yang dapat memulihkan kedip tegangan salah satunya adalah Dynamic Voltage Restorer (DVR). DVR ini posisinya dipasang secara seri antara sumber dan beban, DVR mem
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36

H., S. Chawda, K. Rai Avinash, Rathore R., C. Ameta Suresh, and Ameta R. "Undoped and carbon-doped calcium molybdate as photocatalyst for degradation of methylene blue." Journal of Indian Chemical Society Vol. 97, No. 11b, Nov 2020 (2020): 2397–406. https://doi.org/10.5281/zenodo.5656236.

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Department of Chemistry, PAHER University, Udaipur-313 024, Rajasthan, India Department of Chemistry, B. N. University, Udaipur-313 002, Rajasthan, India Department of Chemistry, J. R. N. Rajasthan Vidhyapeeth (Deemed to be University), Udaipur-313 002, Rajasthan, India <em>E-mail</em>: hardeepshre@gmail.com <em>Manuscript received online 20 October 2020, revised and accepted 28 November 2020</em> Calcium molybdates (undoped and carbon-doped) were synthesized and used as photocatalysts for the degradation of meth&shy;ylene blue. These photocatalysts have been characterized by different techniq
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Vikram, Singh Kumawat, Bhatt Jayesh, Sharma Daksha, Rathore Renu, C. Ameta Suresh, and Ameta Rakshit. "Photodegradation of polypropylene using CaO nanoparticles as a catalyst." Journal of Indian Chemical Society Vol. 97, Jun 2020 (2020): 879–85. https://doi.org/10.5281/zenodo.5658109.

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Department of Chemistry, PAHER University, Udaipur-313 003, Rajasthan, India Department of Chemistry, VBRI, Udaipur-313 002, Rajasthan, India Department of Chemistry, B. N. University, Udaipur-313 001, Rajasthan, India Department of Chemistry, J.R.N. Rajsathan Vidyapeeth (Deemed to be University), Udaipur-313 001, Rajasthan India <em>E-mail:</em> vikramkumawat123@gmail.com, rakshit_ameta@yahoo.in <em>Manuscript received online 30 January 2020, revised and accepted 07 May 2020</em> The photodegradation of polypropylene has been studied using calcium oxide nanoparticles as a catalyst under halog
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38

Szkody, P. "A Photometric and Spectroscopic Comparison of the Cataclysmic Variables on the 2 Sides of the Period Gap and at a Specific Orbital Period." International Astronomical Union Colloquium 93 (1987): 69–73. http://dx.doi.org/10.1017/s0252921100104646.

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AbstractNew and previously existing photometric colors and spectroscopic H and He line strengths are used to compare CV disk systems below the period gap (P=80–130 min) with those directly above (P=190–240 min). Significant differences are found in the mean U-B,V-J colors and in the Hβ equivalent widths on the 2 sides of the gap. A detailed comparison from UV-IR of 3 high inclination novalike systems with periods near 3.3 hr (PG1012−029, PG1030+590 and V1315 Aql) shows similar continuum distributions (and implied mass accretion rates) but large differences in high excitation lines (HeII1640,46
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39

Brustolin, D., M. Maierna, F. Aguzzi, F. Zoppi, G. Tarenghi, and G. Berti. "Immunoturbidimetric method for routine determinations of apolipoproteins A-I and B." Clinical Chemistry 37, no. 5 (1991): 742–47. http://dx.doi.org/10.1093/clinchem/37.5.742.

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Abstract A simple immunoturbidimetric method for quantifying apolipoproteins (apo) A-I and B in serum or plasma is described. A special reagent formulation, including large amounts of suitable detergents, obviates the need for a sample blank even with grossly lipemic specimens. The assay is rapid, easily automated, and thus convenient for routine work. For both apo A-I and apo B, the assay range is about 0.2-3.5 g/L. The performance characteristics were assessed with discrete (Optimate and Olli CD) and centrifugal analyzers (Cobas Fara and IL Monarch 2000). Average analytical recovery was 101.
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40

Madhusudhan, Saha, Karim E., L. Nongkhlaw R., and N. Vishwakarma Jai. "A facile microwave assisted one-pot strategy for the synthesis of bis-hexahydroquinazolin-5(6H)-ones." Journal of Indian Chemical Society Vol. 89, Jan 2012 (2012): 117–20. https://doi.org/10.5281/zenodo.5751793.

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organic Research Lab., Department of Chemistry, St. Anthony&#39;s College, Shillong-793 001, Meghalaya, India <em>E-mail </em>: jnvishwakarma@rediffmail.com Fax : 91-0364-2229558 Department of Chemistry, North-Eastern Hill University, Shillong-793 022, Meghalaya, India <em>Manuscript received OJ November 2010, revised 04 April 2011, accepted 26 May 2011</em> A facile microwave assisted one-pot synthesis of novel bis-hexahydroquinazolin-5(6<em>H</em>)-ones (7a-j) has been devised by the cyclocondensation of cyclic enaminones (6a-b) with diamines and formaldehyde. The structures of the products
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41

Pechkovskii, Grigorii A., Evgeny I. Eremenko, Alla G. Ryazanova, et al. "Development of a technique for molecular typing of <i>Bacillus anthracis</i> strains using new VNTR and INDEL markers." Journal of microbiology, epidemiology and immunobiology 101, no. 3 (2024): 362–71. http://dx.doi.org/10.36233/0372-9311-487.

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Introduction. Bacillus anthracis, the pathogen of a particularly dangerous zoonotic disease known as anthrax, requires strict epidemiological control and is characterized by high genetic homogeneity, which necessitates the development of genotyping methods. The aim of the study were to to find and characterize the VNTR and INDEL loci of B. anthracis and to develop on their basis a genotyping technique by PCR with electrophoretic detection of the results. Materials and methods. Marker search and phylogenetic analysis were performed on a sample of 388 genomes of B. anthracis strains, 322 from th
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42

Tursun, K., C. Henkel, J. Esimbek, et al. "Observations of multiple NH3 transitions in W33." Astronomy & Astrophysics 658 (January 27, 2022): A34. http://dx.doi.org/10.1051/0004-6361/202141937.

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At a distance of 2.4 kpc, W33 is an outstanding massive and luminous 10 pc-sized star forming complex containing quiescent infrared dark clouds as well as highly active infrared bright cloud cores heated by young massive stars. We report measurements of ammonia (NH3) inversion lines in the frequency range 18–26 GHz obtained with the 40′′ resolution of the 100 m Effelsberg telescope. We detect the (J, K) = (1,1), (2,2), (3,3), (4,4), (5,5), (6,6), (2,1), and (3,2) transitions. There is a maser line in the (3,3) transition towards W33 Main. Brightness temperature and line shape indicate no signi
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43

Fernandez-Serrano, Miranda, Nuria Profitos-Peleja, Judith Camalo-Vila, et al. "Abstract 313: Discovery of novel CXCR4 targeting compounds with antitumor activity in preclinical models of diffuse large B-cell lymphoma." Cancer Research 85, no. 8_Supplement_1 (2025): 313. https://doi.org/10.1158/1538-7445.am2025-313.

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The constitutive activation of CXC motif chemokine receptor 4 (CXCR4) is strongly implicated in tumor progression, metastasis, invasion, and chemotherapy resistance. In diffuse large B-cell lymphoma (DLBCL), the most common subtype of mature B-cell non-Hodgkin lymphoma, CXCR4 activation is associated with poor prognosis. Previous attempts to target CXCR4 in this disease using tetraamine-based inhibitors (CXCR4-i) have been limited by suboptimal pharmacological properties. Using structure-based drug design, we identified novel CXCR4-i candidates with potential anti-lymphoma activity. A library
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44

Van der Heijde, D., X. Baraliakos, M. Dougados, et al. "OP0019 BIMEKIZUMAB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 2, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO-CONTROLLED STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 12–13. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2441.

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BackgroundBimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits IL-17F in addition to IL-17A. In a phase 2b study, BKZ showed rapid and sustained efficacy and was well tolerated up to 156 weeks (wks) in patients (pts) with active ankylosing spondylitis (AS).1,2ObjectivesTo assess efficacy and safety of BKZ vs placebo (PBO) in pts with active AS up to Wk 24 in the ongoing pivotal phase 3 study, BE MOBILE 2.MethodsBE MOBILE 2 (NCT03928743) comprises a 16-wk double-blind, PBO-controlled period and 36-wk maintenance period. Pts were aged ≥18 yrs, met modified New York criteria
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45

Shah, Jatin, Joan Blade, Pieter Sonneveld, et al. "The Effect of Paraprotein Heavy Chain and Free Light Chain Types on the Efficacy of Pegylated Liposomal Doxorubicin + Bortezomib Versus Bortezomib Alone in Patients with Relapsed/Refractory Multiple Myeloma." Blood 112, no. 11 (2008): 5190. http://dx.doi.org/10.1182/blood.v112.11.5190.5190.

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Abstract Background: Many factors influence the choice of salvage therapy in relapsed/refractory multiple myeloma (RRMM), including various disease characteristics such as light chain and heavy chain subtypes. Patients with light chain only myeloma are a biologically and phenotypically distinct subset of patients from those with IgG, IgA, IgM, or IgD disease. Evidence exists that the presence of different paraprotein heavy and light chain subtypes may affect treatment outcomes. We investigated the effect of the presence of paraprotein heavy and light chain types on the efficacy and safety of p
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46

Villar, LM, N. García-Barragán, M. Espiño, et al. "Influence of oligoclonal IgM specificity in multiple sclerosis disease course." Multiple Sclerosis Journal 14, no. 2 (2007): 183–87. http://dx.doi.org/10.1177/1352458507082046.

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Oligoclonal IgM bands (OCMB) against myelin lipids predict an aggressive multiple sclerosis (MS) course. However, the clinical significance of OCMB without lipid specificity, present in other MS patients, remains unknown. We describe here a characterization of these antibodies and study their role in MS progression. Fifty-four MS patients showing CSF-restricted OCMB were included in this study at disease onset and followed-up during 61.1 ± 2.7 months. The specificity of OCMB and the CSF B-cell profile were investigated. A second CSF IgM study was performed in a group of eight patients. Thirty-
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47

Tong, Ming-Liang, Ji-Wen Cai, Xiao-Lan Yu, Xiao-Ming Chen, Seik Weng Ng, and Thomas C. W. Mak. "Linear Metal(II)-4,4′-Bipyridine (4,4′-bpy) Chains Organized into Two-Dimensional Rhombic Networks by Hydrogen Bonding. Crystal Structures of [Co(4,4′-bpy)(H2O)4] (ClO4)2.(4,4′-bpy)2.2H2O and [Zn(4,4′-bpy)(H2O)3(ClO4)] (ClO4).(4,4′-bpy)1·5.H20." Australian Journal of Chemistry 51, no. 7 (1998): 637. http://dx.doi.org/10.1071/c97207.

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Two substances with extended two-dimensional networks through hydrogen-bond cross linkages, namely, [Co(4,4′-bpy)(H2O4] (ClO4)2.(4,4′-bpy)2.2H2O and [Zn(4,4′-bpy)(H2O)3(ClO4)] (ClO4).(4,4′- bpy)1·5.H2O, were synthesized, in EtOH/H2O solution. The cobalt complex crystallizes in the triclinic space group P-1 with a 9·113(2), b 11· 093(2), c 11·394(2) Å, α 64·04(3), β 70·18(3), γ 66·91(3)°, V 932·9(3) Å3. The crystal structure contains 4,4′-bpy-bridged linear polymeric [Co(4,4′-bpy)(H2O)4]n chains, where the cobalt(II) is coordinated in a slightly distorted octahedral environment by four water mo
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48

Nauman, Syed Muhammad, Yousaf Haroon, Asrar Ahmad, and Irum Saleem. "SURGICAL SITE INFECTION." Professional Medical Journal 25, no. 01 (2018): 1–4. http://dx.doi.org/10.29309/tpmj/2018.25.01.527.

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Objectives: To compare antibiotic prophylaxis in preventing frequency ofpostoperative surgical site wound infection rate in low risk laparoscopic cholecystectomywith controls. Study design: Randomized Controlled Trial. Setting: Department of Surgery,Combined Military Hospital, Rawalpindi. Duration of study: This study was conducted from11-07-2015 to 10-01-2016. Subjects and methods: A total of 650 patients (325 in each group)were included in the study. Patients in group-A received antibiotic prophylaxis whereas patientsin group-B did not receive any antibiotic prophylaxis. Results: Mean age of
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49

Lada, Olivier, Yves Benhamou, Annie Cahour, Christine Katlama, Thierry Poynard, and Vincent Thibault. "In Vitro Susceptibility of Lamivudine-Resistant Hepatitis B Virus to Adefovir and Tenofovir." Antiviral Therapy 9, no. 3 (2003): 353–63. http://dx.doi.org/10.1177/135965350400900311.

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Emergence of lamivudine-resistant hepatitis B virus (HBV) is a major concern in human immunodeficiency virus (HIV) and HBV coinfected patients. Following selection of resistant mutants, hepatitis flare or rapid progression to cirrhosis may occur. Treatment of patients with new nucleotide analogues such as adefovir dipivoxil (ADV) or tenofovir disoproxil fumarate (TDF) has shown good efficacy in controlling wild-type or lamivudine-resistant HBV replication. The purpose of this study was to assess the in vitro efficacy of new nucleotide analogues on HBV strains isolated from lamivudine-treated p
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50

Harb, Wael, Mansoor N. Saleh, Kyriakos P. Papadopoulos, et al. "Clinical Trial Results from the Subgroup of Lymphoma/CLL in a Phase 1 Study of ARQ 092, a Novel Pan AKT-Inhibitor." Blood 126, no. 23 (2015): 5116. http://dx.doi.org/10.1182/blood.v126.23.5116.5116.

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Abstract Background: ARQ 092 is an oral allosteric, potent and selective AKT inhibitor with in vitro and in vivo activity in solid and hematological tumors. ARQ 092-101, the first clinical trial of ARQ 092, has enrolled more than 100 subjects with advanced solid tumors or recurrent malignant lymphoma. As reported previously, the dose escalation portion of the study has been completed and two dosing schedules (intermittent and weekly), are recommended for phase 2 studies. The recommended phase 2 dose (RP2D) for the intermittent dosing schedule is 200 mg once daily (QD) (one week on, one week of
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