To see the other types of publications on this topic, follow the link: 330.341.1.322 (477) (043.2).

Journal articles on the topic '330.341.1.322 (477) (043.2)'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 31 journal articles for your research on the topic '330.341.1.322 (477) (043.2).'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Sedziol, Carley, Sari Bosnyak, Nadja Knox, Haley Ravia, and Clarence E. Ferguson. "PSXV-16 Association of Experience and pre-Race Behavior in Performance Among Racing Quarter Horses." Journal of Animal Science 100, Supplement_3 (2022): 294. http://dx.doi.org/10.1093/jas/skac247.534.

Full text
Abstract:
Abstract The annual average cost of maintaining a racehorse will typically outweigh its earning, making it important that the horse performs above average. The goal of this study was to investigate if the age or experience level of a racehorse could be associated with performance. This study observed pre-racing Quarter Horses (n = 1,033) behavior during one racing season at Delta Downs racetrack (Vinton, LA). The horses were placed into groups based on race experience (0-2, 3-10, and 11+ total races). Horse pre-race before saddling (BSAD), saddling (SAD), after saddling (ASAD) and post-parade
APA, Harvard, Vancouver, ISO, and other styles
2

Tan, Juanyi, Szu-Chun Yang, Michaela A. Dinan, Anne C. Chiang, Cary P. Gross, and Shi-Yi Wang. "Biomarker-Specific Survival and Medication Cost for Patients With Non–Small Cell Lung Cancer." JAMA Network Open 8, no. 6 (2025): e2514519. https://doi.org/10.1001/jamanetworkopen.2025.14519.

Full text
Abstract:
ImportanceTargeted therapies and immunotherapies prolong survival but are associated with high costs for patients with advanced non–small cell lung cancer (aNSCLC). To date, little is known about survival and medication cost by biomarker status in the US.ObjectiveTo estimate survival and medication cost by aNSCLC biomarker status.Design, Setting, and ParticipantsThis retrospective cohort study using Flatiron Health data identified patients diagnosed with aNSCLC from January 1, 2016, through December 31, 2022. Each patient had received at least 1 biomarker test and 1 documented line of therapy;
APA, Harvard, Vancouver, ISO, and other styles
3

Van der Heijde, D., L. S. Gensler, A. Deodhar, et al. "OP0105 EFFICACY AND SAFETY OF BIMEKIZUMAB IN ANKYLOSING SPONDYLITIS: 48-WEEK PATIENT-REPORTED OUTCOMES FROM A PHASE 2B, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 68–69. http://dx.doi.org/10.1136/annrheumdis-2020-eular.323.

Full text
Abstract:
Background:Bimekizumab (BKZ), a monoclonal antibody that selectively neutralises interleukin (IL)-17A and IL-17F, is a potential therapeutic option in ankylosing spondylitis (AS).Objectives:To report 48-week (wk) patient-reported outcomes (PROs) in patients (pts) with AS treated with BKZ in a phase 2b dose-ranging study (BE-AGILE;NCT02963506).Methods:Pts with active AS (Bath AS Disease Activity Index [BASDAI] ≥4; spinal pain ≥4 [0–10]), fulfilling modified New York criteria (central reading), and inadequate response/intolerance to NSAIDs were randomised according to the study design (Figure 1)
APA, Harvard, Vancouver, ISO, and other styles
4

Bottinor, Wendy, Haoxue Xiang, Yan Chen, et al. "Cardiovascular risk factor severity and adverse cardiovascular events: A report from the Childhood Cancer Survivor Study (CCSS)." Journal of Clinical Oncology 43, no. 16_suppl (2025): 12055. https://doi.org/10.1200/jco.2025.43.16_suppl.12055.

Full text
Abstract:
12055 Background: Among survivors of childhood cancer, more severe grades of CVRFs are associated with increased risk for adverse cardiovascular events (ACE). The impact of low severity CVRFs has not been defined. Methods: Among 25,723 long-term survivors of childhood cancer, CVRF severity was graded using longitudinal self-report: Grade 1 conditions are reported but not on medications; Grade 2 are prescribed medications. Cumulative incidence of CVRFs were estimated into the 6 th decade of life with death and Grade 2 CVRFs a competing risk event for Grade 1 CVRFs. Starting at 1st report of a C
APA, Harvard, Vancouver, ISO, and other styles
5

Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

Full text
Abstract:
BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a
APA, Harvard, Vancouver, ISO, and other styles
6

Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

Full text
Abstract:
Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
APA, Harvard, Vancouver, ISO, and other styles
7

Feldman, Darren R., Patrick Gagnon-Sanschagrin, Jessica Maitland, et al. "Time to real-world progression (TTrwP) among patients (pts) with relapsed/refractory (R/R) testicular germ cell tumors (GCT) undergoing palliative chemotherapy (CT) in the United States (US)." Journal of Clinical Oncology 43, no. 5_suppl (2025): 628. https://doi.org/10.1200/jco.2025.43.5_suppl.628.

Full text
Abstract:
628 Background: Pts with R/R testicular GCT are considered to be incurable, having experienced progressive disease (PD) after salvage conventional-dose CT (CDCT) and/or high-dose CT (HDCT). Therapeutic options are limited to palliative CT, with an estimated real-world (rw) overall survival of 8 months from initiation of their first palliative CT regimen. Understanding TTrwP may help further inform clinical care. Methods: The Komodo Research Database (KRD; 01/2016-03/2023) was used to identify adult males in the US with testicular GCT who received palliative CT after salvage CT. TTrwP was estim
APA, Harvard, Vancouver, ISO, and other styles
8

Durgam, Suresh, Andrew Satlin, Robert E. Davis, Kimberly E. Vanover, Sharon Mates, and John M. Kane. "T205. LUMATEPERONE IN THE TREATMENT OF SCHIZOPHRENIA: EVALUATION OF EXTRAPYRAMIDAL AND MOTOR SYMPTOMS IN 4 LATE-PHASE CLINICAL TRIALS." Schizophrenia Bulletin 46, Supplement_1 (2020): S310. http://dx.doi.org/10.1093/schbul/sbaa029.765.

Full text
Abstract:
Abstract Background Standard of care (SOC) antipsychotics exhibit efficacy at high dopamine D2 receptor occupancy (60%-80%), which is associated with increased risk of extrapyramidal symptoms (EPS). Lumateperone (lumateperone tosylate, ITI-007) is a mechanistically novel antipsychotic that simultaneously modulates serotonin, dopamine, and glutamate neurotransmission. Efficacy of lumateperone 42 mg (ITI-007 60 mg) has been established in randomized placebo-controlled trials and, in contrast to other antipsychotics, occurs at low D2 receptor occupancy (40%). In controlled trials, lumateperone 42
APA, Harvard, Vancouver, ISO, and other styles
9

Gomes, Tiago Halyson de Oliveira, Beatriz Pellizzon, Giovanna Victória Moura Araújo, et al. "MAMOPLASTIA PÓS BARIÁTRICA." Revista ft 29, no. 144 (2025): 02–03. https://doi.org/10.69849/revistaft/fa10202503150102.

Full text
Abstract:
INTRODUÇÃO: A mamoplastia pós bariátrica é um procedimento cirúrgico realizado para remodelar as mamas de pacientes que passaram por cirurgia bariátrica, visando corrigir a flacidez e o excesso de pele resultantes da perda significativa de peso. Esse procedimento é indicado para melhorar a estética e a autoestima dos pacientes, após a redução substancial de peso corporal. OBJETIVOS: O objetivo do presente trabalho foi realizar o levantamento acerca dos procedimentos cirúrgicos de mamoplastia pós bariátrica no Brasil, entre o período de 2013 a 2024. METODOLOGIA: O presente estudo trata-se de um
APA, Harvard, Vancouver, ISO, and other styles
10

Domínguez-Casas, L. C., P. Rodriguez Cundin, T. Dierssen-Sotos, et al. "AB0279 HERPES ZOSTER IN RHEUMATOID ARTHRITIS. PROSPECTIVE SINGLE UNIVERSITY CENTER STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1265.2–1266. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3057.

Full text
Abstract:
BackgroundPatients with Rheumatoid arthritis (RA) have an increased risk of infections due to the disease itself, and/or immunosuppressive therapy. The risk of herpes zoster (HZ) including disseminated HZ is also increased(1)ObjectivesIn an unselected series of RA patientswe assessa)prevalence, b)general features and c) predictive factors of HZ.MethodsStudy of 393 RA patients included in the prospective vaccination program of the Preventive Medicine and Rheumatology department of a University hospital, from October 2011 to October 2016. The minimum follow-up was of 12 months; therefore, it was
APA, Harvard, Vancouver, ISO, and other styles
11

Kasatkin, Anatoly V., Galina S. Anisimova, Fabrizio Nestola, et al. "Amgaite, Tl3+2Te6+O6, a New Mineral from the Khokhoyskoe Gold Deposit, Eastern Siberia, Russia." Minerals 12, no. 9 (2022): 1064. http://dx.doi.org/10.3390/min12091064.

Full text
Abstract:
The new mineral amgaite was discovered at the Khokhoyskoe gold deposit, 120 km W of Aldan town, Aldanskiy District, Sakha Republic (Yakutia), Eastern Siberia, Russia. Amgaite forms fine-grained colloform aggregates up to 0.05 mm across, and is often intimately intergrown with avicennite, unidentified carbonates and antimonates of Tl. Other associated minerals include gold, silver, acanthite, arsenopyrite, pyrite, berthierite, chalcocite, weissbergite, chlorargyrite, calcite, quartz, goethite etc. Amgaite is dark reddish brown to black. It has submetallic luster, black streak, brittle tenacity
APA, Harvard, Vancouver, ISO, and other styles
12

Galvis Rojas, Giovanni, Magnus Husberg, and Lars-Ake Levin. "Cost-effectiveness analysis of population-based screening for 6-gene panel testing for hereditary breast and ovarian cancer." Journal of Clinical Oncology 43, no. 16_suppl (2025): 10541. https://doi.org/10.1200/jco.2025.43.16_suppl.10541.

Full text
Abstract:
10541 Background: Genetic testing for hereditary breast and ovarian cancer (HBOC) has relied on clinical and family history criteria. This approach, has been shown to overlook a significant number of mutation carriers who could benefit from preventative measures. Increasing evidence supports genetic testing in an unselected population, which facilitates the identification of more carriers and allows for the implementation of risk reduction strategies. The aim of this study is to evaluate the cost-effectiveness of utilising an expanded gene-panel in an unselected female population. Methods: A M
APA, Harvard, Vancouver, ISO, and other styles
13

Castrejon, I., J. Molina Collada, C. Perez-Garcia, et al. "POS1439 CANCER IN PATIENTS WITH RHEUMATIC DISEASES EXPOSED TO DIFFERENT BIOLOGIC AND TARGETED SYNTHETIC DMARDS IN REAL-WORLD CLINICAL PRACTICE: DATA FROM A MULTICENTER REGISTER." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1063. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3834.

Full text
Abstract:
BackgroundExtensive evidence has confirmed no increased risk of cancer associated to either conventional synthetic DMARDs or anti-TNF in patients with rheumatic diseases. The risk of cancer in biologic (bDMARDs) different to anti-TNF and targeted synthetic (tsDMARDs) is considerably less investigated. As new therapies are emerging, more data in real-world registries are needed to confirm safety in other treatment groups.ObjectivesTo compare the risk of cancer of tsDMARDs and other bDMARDs versus anti-TNF in patients with rheumatic diseases.MethodsData of patients enrolled in BIOBADASER 3.0 up
APA, Harvard, Vancouver, ISO, and other styles
14

Ritchlin, C. T., P. Rahman, P. Helliwell, et al. "AB0538 POOLED SAFETY RESULTS FROM TWO PHASE-3 TRIALS OF GUSELKUMAB IN PATIENTS WITH PSORIATIC ARTHRITIS THROUGH 1 YEAR." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1300–1301. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1334.

Full text
Abstract:
Background:DISCOVER 1 & 2, two double-blind, phase-3, psoriatic arthritis (PsA) trials of guselkumab (GUS, an IL-23 inhibitor), demonstrated significant improvement with GUS vs placebo (PBO) in signs and symptoms of PsA, with good tolerability, at week (w) 24 during the PBO-controlled period.1,2 Beyond w24, all patients (pts) switched to GUS. Continued treatment maintained efficacy through w52.3,4Objectives:To describe pooled safety results from the DISCOVER 1 & 2 trials through 1-year of GUS treatment.Methods:Adults with active PsA (DISCOVER 1: ≥3 tender/swollen joints and C-Reactive
APA, Harvard, Vancouver, ISO, and other styles
15

Ramiro, S., D. Poddubnyy, P. J. Mease, et al. "POS0247 RESOLUTION OF ENTHESITIS AND PERIPHERAL ARTHRITIS WITH BIMEKIZUMAB IN PATIENTS WITH AXIAL SPODYLOARTHRITIS: WEEK 52 RESULTS FROM THE BE MOBILE 1 AND BE MOBILE 2 PHASE 3 STUDIES." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 358–59. http://dx.doi.org/10.1136/annrheumdis-2023-eular.831.

Full text
Abstract:
BackgroundA history of enthesitis or peripheral arthritis has been reported in >30% of patients (pts) with axial spondyloarthritis (axSpA),[1]both of which contribute to disease burden. Bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A, has demonstrated efficacy in phase 3 parallel studies in pts with non-radiographic (nr-)axSpA (BE MOBILE 1) and radiographic axSpA (r-axSpA i.e. ankylosing spondylitis; BE MOBILE 2).[2,3]ObjectivesTo evaluate the impact of BKZ on the main peripheral manifestations of axSpA, to Week (Wk) 52.Meth
APA, Harvard, Vancouver, ISO, and other styles
16

Attanasio, L., A. De Rosa, L. Boccia, R. Di Palo, G. Campanile, and B. Gasparrini. "68 EFFECT OF CO-CULTURE DURING FERTILIZATION OF BUFFALO (BUBALUS BUBALIS) IN VITRO-MATURED DENUDED OOCYTES VITRIFIED BY CRYOTOP." Reproduction, Fertility and Development 20, no. 1 (2008): 115. http://dx.doi.org/10.1071/rdv20n1ab68.

Full text
Abstract:
Although removal of cumulus cells improves the efficiency of vitrification of buffalo (Bubalus bubalus) in vitro-matured (IVM) oocytes (Gasparrini et al. 2007 Anim. Reprod. Sci. 98, 335–342), the lack of cells impairs the fertilization process. Therefore, the aim of the present work was to evaluate the influence of a somatic support during in vitro fertilization (IVF) of buffalo vitrified denuded matured oocytes. Since IVF on a cumulus cells monolayer was inefficient, we verified the effects of co-culture with cumulus-enclosed oocytes (COCs). IVM buffalo oocytes (n = 316) were vitrified by the
APA, Harvard, Vancouver, ISO, and other styles
17

Kraft, Daniel L., and Irving L. Weissman. "Effect and Kinetics of Depleting ACK-2 Anti C-Kit Monoclonal Antibody on Hematopoeisis and Hematopoetic Progenitors and Ability To Condition for Bone Marrow Transplantation." Blood 104, no. 11 (2004): 4963. http://dx.doi.org/10.1182/blood.v104.11.4963.4963.

Full text
Abstract:
Abstract c-kit is expressed on hematopoetic stem and progenitor cell populations. ACK-2 is an anti-mouse c-Kit monoclonal antibody which has been shown (by Nishikawa et al) to antagonize the function of c-kit and deplete the bone marrow of treated mice. We wished to characterize the effect of the anti c-kit mAb ACK-2 on the peripheral blood cell counts and marrow hematopoetic stem cell and progenitor populations. We also tested the hypothesis that treatment with ACK-2 may serve as a novel means of non-myeloablative conditioning for hematopoeitic stem cell transplantation. METHODS: Adult C57 bl
APA, Harvard, Vancouver, ISO, and other styles
18

Ignatieva, V. I., S. G. Opimakh, D. V. Dobrianskyi, G. L. Gumeniuk, R. I. Ilnytskyi, and N. M. Kuzmenko. "Application of acetylcysteine in inhalation form in complex treatment of patients with bronchial asthma with neutrophilic type of inflammation." Infusion & Chemotherapy, no. 3.1 (October 11, 2020): 34–36. http://dx.doi.org/10.32902/2663-0338-2020-3.1-28.

Full text
Abstract:
Background. Bronchial asthma (BA) is a heterogeneous chronic inflammatory disease of the airways. On the base of this heterogeneity, among other factors, a significant role is played by the type of inflammation (eosinophilic, neutrophilic or malogranulocytic). In this regard it is offered to allocate separate endotypes of the disease. BA with a neutrophilic type of inflammation is characterized by more severe course with the presence of obstruction at the level of small bronchi and fixed bronchoobstruction. In the presence of disorders at the level of small bronchi, it is advisable to prescrib
APA, Harvard, Vancouver, ISO, and other styles
19

Baraliakos, X., E. Pournara, D. D. Gladman, P. J. Mease, S. Jahandideh, and L. Coates. "POS1110 PATIENT CLUSTERS IDENTIFIED BY MACHINE LEARNING: DATA FROM A POOLED ANALYSIS OF PHASE-3 TRIALS OF SECUKINUMAB IN PSORIATIC ARTHRITIS, ANKYLOSING SPONDYLITIS AND PSORIATIC ARTHRITIS WITH AXIAL MANIFESTATIONS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 879.1–879. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2975.

Full text
Abstract:
BackgroundUniversally acceptable criteria to define axial psoriatic arthritis (PsA) are lacking. Machine learning (ML) algorithms can detect patterns from large clinical datasets and identify clusters with potential therapeutic or prognostic significance in PsA patients (pts) with axial manifestations.[1]ObjectivesTo identify pt clusters based on baseline (BL) demographics and clinical indicators to support characterisation of the axial PsA phenotype within the spondyloarthritis (SpA) spectrum.MethodsPooled BL demographics and clinical data of secukinumab (SEC)-treated pts from 10 Phase-3 stud
APA, Harvard, Vancouver, ISO, and other styles
20

Magnus, Dan, Santosh Bhatta, and Julie Mytton. "432 Establishing injury surveillance in emergency departments in Nepal: epidemiology and burden of paediatric injuries." Emergency Medicine Journal 37, no. 12 (2020): 825.2–827. http://dx.doi.org/10.1136/emj-2020-rcemabstracts.7.

Full text
Abstract:
Aims/Objectives/BackgroundGlobally, injuries cause more than 5 million deaths annually. Children and young people are a particularly vulnerable group and injuries are the leading cause of death in people aged 5–24 years globally and a leading cause of disability.In most low and middle-income countries where the majority of global child injury burden occurs, systems for routinely collecting injury data are limited. There is a continuing need for better data on childhood injuries and for injury surveillance.The aim of our study was to introduce a hospital-based injury surveillance tool – the fir
APA, Harvard, Vancouver, ISO, and other styles
21

Deodhar, A., I. Mcinnes, X. Baraliakos, et al. "FRI0272 SECUKINUMAB DEMONSTRATES A CONSISTENT SAFETY PROFILE IN PATIENTS WITH PSORIASIS, PSORIATIC ARTHRITIS AND ANKYLOSING SPONDYLITIS OVER LONG TERM: UPDATED POOLED SAFETY ANALYSES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 722.2–722. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5118.

Full text
Abstract:
Background:Pooled safety data has been reported with secukinumab (SEC) in patients (pts) with Psoriatic arthritis (PsA), Ankylosing Spondylitis (AS) and Psoriasis (PsO).1Objectives:To report longer-term safety data of SEC treatment in PsA, AS, PsO pts up to 5 years.Methods:The integrated clinical trial safety dataset included data pooled from 28 randomised controlled clinical trials of SEC 300 or 150 or 75 mg in PsO (11 Phase 3 and 8 Phase 4 trials), PsA (5 Phase 3 trials), and AS (4 Phase 3 trials), along with post-marketing safety surveillance data with a cut-off date of 25 December 2018. Ad
APA, Harvard, Vancouver, ISO, and other styles
22

Cohen, S. B., H. Schulze-Koops, J. Pope, et al. "POS0827 CLINICAL OUTCOMES OF PATIENTS WITH RHEUMATOID ARTHRITIS WHO DISCONTINUED TOFACITINIB OR TUMOUR NECROSIS FACTOR INHIBITORS: RESULTS FROM ORAL SURVEILLANCE." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 710–11. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2670.

Full text
Abstract:
BackgroundSwitching or discontinuing therapy may occur in patients (pts) with rheumatoid arthritis (RA) with an inadequate response/intolerance to treatment. In ORAL Surveillance, a post-authorisation safety study of tofacitinib vs tumour necrosis factor inhibitors (TNFi) in pts with RA despite methotrexate aged ≥50 years with ≥1 additional cardiovascular risk factor,[1]pts could discontinue the assigned study drug and switch to local standard of care (SOC) treatment and, in contrast to previous randomised controlled trials, were encouraged to remain in the study.ObjectivesTo assess efficacy/s
APA, Harvard, Vancouver, ISO, and other styles
23

Mariette, X., S. Borchmann, S. Aspeslagh, et al. "POS0824 CARDIOVASCULAR (CV) AND MALIGNANCY EVENTS IN THE FILGOTINIB (FIL) RHEUMATOID ARTHRITIS (RA) CLINICAL DEVELOPMENT PROGRAM UP TO 8.3 YEARS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 707.1–708. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1425.

Full text
Abstract:
BackgroundFIL is a Janus kinase (JAK) 1 preferential inhibitor for the treatment of RA. Data from the ORAL Surveillance post-marketing study (NCT02092467) suggest that in patients with active RA aged ≥50 years with ≥1 CV risk factor, the risks of cancer and major adverse cardiovascular events (MACE) are higher with the pan-JAK inhibitor tofacitinib vs tumor necrosis factor inhibitors, with higher rates in those aged ≥65 vs <65 years.[1]ObjectivesTo assess the incidence of malignancies excluding non-melanoma skin cancer (NMSC), NMSC, MACE and venous thromboembolism (VTE) in patients treated
APA, Harvard, Vancouver, ISO, and other styles
24

Nipa, Shamima Islam, David Cooper, Alyaa Mostafa, Suzanne Hagen, and Mohamed Abdel-Fattah. "Novel clinically meaningful scores for the ICIQ-UI-SF and ICIQ-FLUTS questionnaires in women with stress incontinence." International Urogynecology Journal, October 11, 2023. http://dx.doi.org/10.1007/s00192-023-05657-4.

Full text
Abstract:
Abstract Aim To establish, for the first time, the clinically important differences for the ICIQ-UI-SF and ICIQ-FLUTS questionnaires following surgical and conservative treatments for stress-predominant urinary incontinence in women. Methods Data from the SIMS and OPAL randomised controlled trials were analysed using an anchor-based method. Clinically important difference (CID; score change indicating a successful outcome) and minimal important difference (MID; score change indicating the smallest noticeable difference) were estimated using the PGI-I scale as the anchor. Results For ICIQ-UI-SF
APA, Harvard, Vancouver, ISO, and other styles
25

Solis-Sánchez, Gilmer, Maricela Curisinche-Rojas, Margot Haydee Vidal-Anzardo, Oscar Augusto Lengua-Olivares, Cristian Pacheco, and Karina Mayra Aliaga Llerena. "Variation in mortality from digestive system cancers in Peru during the period 2001–2020 and its prediction to 2030." Journal of Clinical Oncology 43, no. 16_suppl (2025). https://doi.org/10.1200/jco.2025.43.16_suppl.e15689.

Full text
Abstract:
e15689 Background: This study identifies changes in mortality from digestive system cancers in Peru during the period 2001–2020 and predict trends up to 2030. Methods: We analyzed records of deaths caused by digestive system cancers (esophagus, stomach, small bowel, colon, rectum, anus, liver and intrahepatic biliary system, gallbladder, extrahepatic biliary system, pancreas) in Peru from the 2001–2020 WHO mortality database. Age-standardized mortality rates (ASMR) per 100,000 population were calculated, along with the difference in ASMR between the extremes of the study period. Predictions fo
APA, Harvard, Vancouver, ISO, and other styles
26

Bami, K., S. Gandhi, H. Leong-Poi, et al. "P1500Effects of empagliflozin on cardiac function in patients with type 2 diabetes mellitus: echocardiographic substudy of the EMPA-HEART cardiolink-6 trial." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0263.

Full text
Abstract:
Abstract Background The EMPA-HEART trial showed a reduction in left ventricular (LV) mass index by cardiac MRI at 6 months in patients treated with Empagliflozin vs placebo. A secondary analysis of key echocardiographic parameters was performed to provide further insight into the mechanism of LV remodeling. Methods All patients enrolled prospectively underwent transthoracic echocardiography (TTE) at baseline and at 6 months. Measurements were performed according to the American Society of Echocardiography guidelines. Key outcomes of interest included changes in diastolic function and right ven
APA, Harvard, Vancouver, ISO, and other styles
27

Du, Mengxi, and Fang Fang Zhang. "Dietary Supplement Use Among Adult Cancer Survivors in the United States." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.168.6.

Full text
Abstract:
BackgroundMany cancer patients initiated supplement use after cancer diagnosis and yet the effect of supplement use on survival has not been established. The trend of and factors associated with dietary supplement use in cancer survivors warrant further investigation.MethodsWe examined the trend of dietary supplemental use in 1,902 adult cancer survivors who participated in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2012, and compared the frequency of supplement use in cancer survivors to that of 3,804 individuals with no history of cancer who were matched to th
APA, Harvard, Vancouver, ISO, and other styles
28

Gibble, T. H., D. Cao, T. D. Forrester, and J. F. Brumm. "8366 Weight Reduction is Associated with Improved Quality of Life in Patients in SURMOUNT-3." Journal of the Endocrine Society 8, Supplement_1 (2024). http://dx.doi.org/10.1210/jendso/bvae163.053.

Full text
Abstract:
Abstract Disclosure: T.H. Gibble: Employee; Self; Eli Lilly & Company. Stock Owner; Self; Eli Lilly & Company. D. Cao: Employee; Self; Eli Lilly & Company. Stock Owner; Self; Eli Lilly & Company. T.D. Forrester: Employee; Self; Eli Lilly & Company. Stock Owner; Self; Eli Lilly & Company. J.F. Brumm: Employee; Self; Eli Lilly & Company. Stock Owner; Self; Eli Lilly & Company. Tirzepatide, a once-weekly glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, is approved in the US for treatment of type 2 diabetes and obesity. In S
APA, Harvard, Vancouver, ISO, and other styles
29

Hoek, A., Z. Wang, M. Van Faassen, et al. "P-443 Resumption of ovulation during lifestyle intervention in anovulatory women with PCOS and obesity is associated with reduction of serum AMH and androgens concentrations." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.791.

Full text
Abstract:
Abstract Study question Are there differences in AMH and androgens concentrations between women with PCOS who resume ovulation (RO+) and those remain anovulatory (RO-) during lifestyle intervention? Summary answer RO+ women showed significant decrease in AMH and 11β-hydroxyandrostenedione concentrations at three months, and increase in SHBG concentrations at six months compared to RO- women. What is known already Lifestyle interventions have been shown to reduce clinical and biochemical hyperandrogenism in women with PCOS. Weight loss of 5-10% may reverse anovulatory status, thereby increasing
APA, Harvard, Vancouver, ISO, and other styles
30

Dolomatov, S.I., та W. Zukow. "Эпигенетика почек = Kidneys epigenetics". 7 липня 2019. https://doi.org/10.5281/zenodo.3270754.

Full text
Abstract:
<strong>Dolomatov S.I., Zukow W. </strong><strong>Эпигенетика почек</strong><strong> = Kidney</strong><strong>s</strong><strong> epigenetics</strong><strong>. </strong><strong>RSW. Radom,</strong><strong> 144 </strong><strong>p. ISBN </strong><strong>9780359774524</strong><strong>.</strong><strong> DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.3270699</strong><strong> PBN Poland </strong><strong>https://pbn.nauka.gov.pl/sedno-webapp/works/917606</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>Radomska Szkoła Wyższa w Radomiu, Radom, Poland</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp
APA, Harvard, Vancouver, ISO, and other styles
31

Kojo, Kosuke, Tomoko Oguri, Takazo Tanaka, et al. "Seminal plasma metallomics: a new horizon for diagnosing and managing male infertility." Revista Internacional de Andrología 23, Published Ahead of Print (2025). https://doi.org/10.22514/j.androl.2025.013.

Full text
Abstract:
The authors, Kosuke Kojo and Tomoko Oguri, contributed equally. This HTML edition is publicly accessible at the following URL:https://academic298uro.github.io/open-archive/2025/seminal-plasma-metallomics-new-horizon/ Abstract Seminal plasma contains a wide range of biomolecules&mdash;including inorganic elements&mdash;that may significantly influence male reproductive function. Historically, semen analysis has focused on sperm count and motility, while overlooking the diagnostic potential of this acellular fraction. This narrative review synthesizes historical perspectives on seminal plasma me
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!