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Journal articles on the topic '339.7 (043.2)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Lakshmanan, Aparna, Anna Wojcicka, Marta Kotlarek, Xiaoli Zhang, Krystian Jazdzewski, and Sissy M. Jhiang. "microRNA-339-5p modulates Na+/I− symporter-mediated radioiodide uptake." Endocrine-Related Cancer 22, no. 1 (2014): 11–21. http://dx.doi.org/10.1530/erc-14-0439.

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Na+/I−symporter (NIS)-mediated radioiodide uptake (RAIU) serves as the basis for targeted ablation of thyroid cancer remnants. However, many patients with thyroid cancer have reduced NIS expression/function and hence do not benefit from radioiodine therapy. microRNA (miR) has emerged as a promising therapeutic target in many diseases; yet, the role of miRs in NIS-mediated RAIU has not been investigated.In silicoanalysis was used to identify miRs that may bind to the 3′UTR of humanNIS(hNIS). The top candidate miR-339-5p directly bound to the 3′UTR of hNIS. miR-339-5p overexpression decreased NI

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Bektaş, M., S. Yüce, M. Ay, M. Uyar, M. Önder, and M. İ. Kiliç. "POS0555 HIGH DOSE INTRAVENOUS ANAKINRA TREATMENT IS SAFE AND EFFECTIVE IN SEVERE AND CRITICAL COVID-19 PATIENTS: A PROPENSITY SCORE MATCHED STUDY IN A SINGLE CENTER." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 544. http://dx.doi.org/10.1136/annrheumdis-2023-eular.339.

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BackgroundIn COVID-19 severe disease course such as need of intensive care unit (ICU) as well as development of mortality is mainly due to cytokine storm.ObjectivesIn this study, we aimed to evaluate the high dose intravenous anakinra treatment response and outcome in patients with severe and critical COVID-19 compared to standard of care.MethodsThis retrospective observational study was carried out at a tertiary referral center. The study population consisted of two groups as follows; the patients receiving high dose intravenous anakinra (anakinra group) between 01.09.2021 and 01.02.2022 and

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Okanli, Ayşe, Merve İnan Budak, Emine Yilmaz, and Yusuf Özay Ozdemir. "Stigma Resistance Scale: A Psychometric Study in a Turkish Mental Illness Sample." Psychiatric Annals 53, no. 7 (2023): 333–39. http://dx.doi.org/10.3928/00485713-20230207-04.

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The aim of this study was to evaluate the reliability and validity of the Turkish version of the Stigma Resistance Scale in patients with psychiatric disorders. This methodological study included 190 patients diagnosed with various psychiatric disorders in a psychiatry outpatient clinic of two hospitals in Turkey. The data were analyzed using SPSS and LISREL software. Explanatory and confirmatory factor analyses, Cronbach's alpha coefficients, and test-retest methods were used to determine the validity and reliability of the scale. The Cronbach's alpha coefficient of the scale was 0.89 for the

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Tonegawa-Kuji, Reina, Yuko Y. Inoue, Michikazu Nakai, et al. "Differences in patient characteristics, clinical practice and outcomes of cardiac implantable electric device therapy between Japan and the USA: a cross-sectional study using data from nationally representative administrative databases." BMJ Open 13, no. 1 (2023): e068124. http://dx.doi.org/10.1136/bmjopen-2022-068124.

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ObjectivesTo identify differences in patient characteristics, clinical practice and outcomes of cardiac implantable electronic device (CIED) therapy between Japan and the USA.DesignA cross-sectional study.SettingNationally representative administrative databases from Japan and the USA containing hospitalisations with first-time implantations of pacemakers, implantable cardioverter-defibrillators (ICD) and cardiac-resynchronisation therapy with or without defibrillators (CRTP/CRTD).ParticipantsPatients hospitalised with first-time implantations of CIEDs.Outcome measuresIn-hospital mortality, in

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Stephanie, Thiant, Jacques Trauet, Eva De Berranger, et al. "Immune Reactions Following Reduced-Intensity Allogeneic Stem Cell Transplantation (Allo-CST): Role of Plasma IL-7 and IL-15 Levels, and Their Receptors." Blood 116, no. 21 (2010): 1251. http://dx.doi.org/10.1182/blood.v116.21.1251.1251.

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Abstract Abstract 1251 Allogeneic stem cell transplantation (allo-SCT) following reduced-intensity conditioning (RIC) represents a concrete alternative to standard myeloablative conditioning. Even though, immune reactions observed after RIC (i.e. GVHD, GVL.), tend to be similar to those observed after myeloablative regimens, there are many differences in their clinical features, timing of onset, and their impact on patient's outcome. The homeostatic cytokines, IL-7 and IL-15 are essential driving forces for homeostatic peripheral expansion of T lymphocytes that are responsible, not only for GV

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Itzykson, Raphael, Elise Fournier, Céline Berthon, et al. "Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy." Blood 138, no. 7 (2021): 507–19. http://dx.doi.org/10.1182/blood.2021011103.

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Abstract To design a simple and reproducible classifier predicting the overall survival (OS) of patients with acute myeloid leukemia (AML) ≥60 years of age treated with 7 + 3, we sequenced 37 genes in 471 patients from the ALFA1200 (Acute Leukemia French Association) study (median age, 68 years). Mutation patterns and OS differed between the 84 patients with poor-risk cytogenetics and the 387 patients with good (n = 13), intermediate (n = 339), or unmeasured (n = 35) cytogenetic risk. TP53 (hazards ratio [HR], 2.49; P = .0003) and KRAS (HR, 3.60; P = .001) mutations independently worsened the

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Pontefract, Benjamin, and Karl Madaras-Kelly. "1470. Linezolid for Treatment of Urinary Tract Infections Caused by Vancomycin-resistant Enterococci." Open Forum Infectious Diseases 6, Supplement_2 (2019): S537. http://dx.doi.org/10.1093/ofid/ofz360.1334.

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Abstract Background Urinary tract infections (UTI) caused by vancomycin-resistant enterococcus (VRE) are difficult to manage due to lack of effective oral treatment options. Linezolid is an antibiotic with activity against VRE that is available orally, but only 30% of each dose is excreted in the urine. Data on the efficacy of linezolid in the treatment of UTI is limited. The purpose of this analysis was to assess the comparative efficacy of linezolid to other VRE-active antibiotics in the treatment of UTI. Methods A national retrospective cohort of inpatient veterans with a positive urine cul

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Pigneux, Arnaud, Jean-Luc Harousseau, Francis Witz, et al. "Addition of Lomustine to Idarubicin and Cytarabine Improves the Outcome of Elderly Patients With De Novo Acute Myeloid Leukemia: A Report From the GOELAMS." Journal of Clinical Oncology 28, no. 18 (2010): 3028–34. http://dx.doi.org/10.1200/jco.2009.26.4648.

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Purpose No significant improvement in treatment outcome has been seen in elderly patients with acute myeloid leukemia (AML) over the past 20 years. This retrospective analysis investigated the prognostic factors for complete remission (CR) and survival in older patients with AML. Patients and Methods The study involved 847 patients older than 60 years enrolled onto three trials carried out in France between 1995 and 2005. Induction therapy consisted of idarubicin (8 mg/m2, days 1 through 5) and cytarabine (100 mg/m2, days 1 through 7; group I, 339 patients) or the same drugs plus lomustine (20

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Bizino, Maurice B., Ingrid M. Jazet, Paul de Heer, et al. "Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation." Diabetologia 63, no. 1 (2019): 65–74. http://dx.doi.org/10.1007/s00125-019-05021-6.

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Abstract Aims/hypothesis The aim of this work was to assess the effect of liraglutide on ectopic fat accumulation in individuals with type 2 diabetes mellitus. Methods This study is a pre-specified subanalysis of the MAGNetic resonance Assessment of VICTOza efficacy in the Regression of cardiovascular dysfunction In type 2 diAbetes mellitus (MAGNA VICTORIA) study, with primary endpoints being the effects of liraglutide on left ventricular diastolic and systolic function. The MAGNA VICTORIA study was a single-centre, parallel-group trial in 50 individuals with type 2 diabetes mellitus (BMI >

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Sa`ad H. Mohammed, Manaf Muwafak Ahmed, and Ruaa Allawy Hasan. "Evaluate of newborn with jaundice at central teaching hospital of pediatrics in Baghdad : descriptive study." Al Mustansiriyah Journal of Pharmaceutical Sciences 23, no. 2 (2023): 158–67. http://dx.doi.org/10.32947/ajps.v23i2.1017.

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Background: - Neonatal jaundice is a frequent condition at newborns, particularly in the first few days after delivery, and it has to be treated well to prevent complications that might have significant, long-lasting complications. Objective: - To assess the outcome of newborn jaundice at the central teaching Hospital of pediatrics in Baghdad using different modality of treatments. Patients and Methods: - A retrospective study is done depending on the medical data of infants have jaundice who were admitted to the neonate units of the central teaching hospital within the period of a

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Komrokji, Rami S., Muhammad Ammad-ud-din, Najla H. Al Ali, et al. "Hematological Response to Frontline Treatment in Lower Risk Myelodysplastic Syndromes (LRMDS) Is Associated with Better Overall Survival." Blood 142, Supplement 1 (2023): 1867. http://dx.doi.org/10.1182/blood-2023-186843.

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Background The majority of LRMDS patients (pts) (70%) do not progress but unfortunately succumb to complications related to cytopenia, namely anemia and red blood cell transfusion dependency (RBC-TD) or their interplay with co-morbidities. RBC-TD is associated with worse outcome reflecting bone marrow failure and long-term sequela of RBC-TD. There is growing evidence that response to treatment and RBC transfusion independence (TI) are associated with favorable outcome. In lieu of 2 recent randomized clinical trials demonstrating efficacy of luspatercept & imetelstat in LRMDS, we assessed t

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Semenova, Lioubov I., and Allan H. White. "Structural Systematics of Rare Earth Complexes. XIX (Hydrated) 1 : 2 Mononuclear Adducts of Lanthanoid(III) Chlorides with 2,2′-Bipyridine and 1,10-Phenanthroline." Australian Journal of Chemistry 52, no. 6 (1999): 571. http://dx.doi.org/10.1071/ch98052.

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Room-temperature single-crystal X-ray structure determinations are recorded for a number of adducts of hydrated lanthanoid(III) trichlorides with 2,2′-bipyridine (‘bpy’) and 1,10-phenanthroline (‘phen’), crystallized from water, methanol or ethanol solutions, containing mononuclear arrays with 1 : 2 Ln/bpy or phen stoichiometry. LaCl3/phen/H2O(1 : 3 : 9), [(phen)2La(OH2)5]Cl3.phen.4H2O, although of overall 1 : 3 LaCl3/phen stoichiometry, has a lattice phen; it is orthorhombic, Pnna, a 19·947(7), b 16·457(5), c 12·213(2) Å, Z = 4; conventional R on |F| was 0·030 for No 2567 ‘observed’ (I >3σ

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Abou Alaiwi, Sarah, Dylan J. Martini, Wanling Xie, et al. "Safety and efficacy of restarting immune checkpoint inhibitors (CPI) after immune-related adverse events (irAEs) in metastatic renal cell carcinoma (mRCC)." Journal of Clinical Oncology 37, no. 7_suppl (2019): 652. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.652.

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652 Background: CPI can induce a range of irAEs with various degrees of severity. Clinical experience with retreatment following clinically significant irAEs is growing. Methods: We retrospectively reviewed mRCC patients treated with CPI-based regimens who had >1 week therapy delay for irAEs at Dana Farber and Emory to characterize the safety and outcomes of retreatment. Toxicity was graded by CTCAEv5. Patients were divided into retreatment (R) and discontinuation (D) cohorts. Patient characteristics were compared by Fisher’s exact test or Wilcoxon’s rank sum test. ORR, OS and PFS were asse

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Nimptsch, Katharina, Jürgen Janke, Tobias Pischon, and Jakob Linseisen. "Association between dietary factors and plasma fetuin-A concentrations in the general population." British Journal of Nutrition 114, no. 8 (2015): 1278–85. http://dx.doi.org/10.1017/s0007114515002639.

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AbstractCirculating fetuin-A, a novel marker for hepatic fat accumulation, has been related to a higher risk of type 2 diabetes and cardiovascular diseases in a growing number of prospective studies. However, little is known about dietary determinants of fetuin-A concentrations in the general population. Therefore, we aimed to investigate the association between dietary intake of energy, energy-providing nutrients, alcohol and major food groups and plasma fetuin-A concentrations in the Bavarian Food Consumption Survey II. Dietary intake was assessed by three 24-h dietary recalls, and plasma co

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Bagbi, B. M. Bagbi, and M. B. Alagala. "Prescription Pattern of Antimalarial Drugs in Two Secondary Health Facilities in Rivers State, Nigeria." Journal of Drug Delivery and Therapeutics 15, no. 6 (2025): 150–54. https://doi.org/10.22270/jddt.v15i6.7241.

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Background: Malaria is a major public health problem and is still accounting for increased morbidity and mortality till date when not properly treated. It is caused by species of the parasite, Plasmodium of which P.falciparum is mostly implicated. The disease burden is still very high in Nigeria where it accounts for more cases and deaths than any other country in the world. Prescription practices have been shown to influence the emergence of resistance to antimalarial drugs2 Objective: To assess the prescription pattern of antimalarials in adults at two secondary health facilities in Rivers S

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Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a

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Riley, M. W., and G. L. Uglem. "Proterometra macrostoma (Digenea: Azygiidae): variations in cercarial morphology and physiology." Parasitology 110, no. 4 (1995): 429–36. http://dx.doi.org/10.1017/s0031182000064763.

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SUMMARYSnails, Elimia semicarinata, infected with Proterometra macrostoma were collected monthly in 1990 and 1991 from North Elkhorn Creek near Lexington, Kentucky, and kept on a 12:12 h light–dark cycle for 2 weeks. Cercariae emerging from snails were classified into 8 strains (I–VIII) based on differences in number and distribution of spined and spineless papillae on the tail. Cercariae also had unique patterns of emergence, swimming behaviour and infectivity in 4 species of sunfish. Of 513 infected snails collected in May, 339 had pure infections with the strain frequencies (% of 339): I, 4

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Epis, Michael R., Keith M. Giles, Patrick A. Candy, Rebecca J. Webster, and Peter J. Leedman. "miR-331-3p regulates expression of neuropilin-2 in glioblastoma." Journal of Neuro-Oncology 116, no. 1 (2013): 67–75. http://dx.doi.org/10.1007/s11060-013-1271-7.

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Aoki, Koyu, Hiroki Minoda, Yasumasa Tanishiro, and Katsumichi Yagi. "REM Studies of Adsorption-Induced Phase Transitions and Faceting in the Si(111)-Au System." Surface Review and Letters 05, no. 03n04 (1998): 653–63. http://dx.doi.org/10.1142/s0218625x98001018.

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Initial stages of Au adsorption processes on Si(111)-(7 × 7) surfaces at ~780°C, a temperature range where the surface structure undergoes successive phase transitions [(7 × 7)–("1 × 1")–(5×2)–("1 × 1")], were observed in situ by reflection electron microscopy. All of the phase transitions are heterogeneous on the surface and start at surface atomic steps. During Au adsorption on Si(111)-(7 × 7), and subsequently on Si(111)-("1 × 1") surface with wide terraces, steps advance toward the step-down direction. At a Au coverage of ~0.3 ML, the 5 × 2 structure nucleates at step edges, and the nuclei

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Juan, Sze Joo, Ghee Hian Lim, and Beng Leong Lim. "Audit of documentation proficiency of emergency department patients who are discharged against medical advice before and after implementation of a checklist." Journal of Hospital Administration 5, no. 4 (2016): 28. http://dx.doi.org/10.5430/jha.v5n4p28.

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Objective: Documentation of the discharge against medical advice (AMA) is poorly performed in the emergency department (ED). Little is known about the impacts of a checklist on this. Our study aimed to compare the quality of AMA documentation before and after implementation of a checklist.Methods: A retrospective review was conducted followed by a prospective study; each over three months of AMA interactions in our ED pre and post implementation of a checklist. An 11-point checklist was used to determine documentation quality during these two periods. Quality was assessed based on the number o

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Bar, Merav, Mary Flowers, Barry E. Storer, et al. "Reversal of Low Donor Chimerism Following Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion." Blood 128, no. 22 (2016): 2215. http://dx.doi.org/10.1182/blood.v128.22.2215.2215.

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Abstract Objectives: Low donor chimerism after hematopoietic cell transplantation (HCT) is associated with increased risk of post transplant relapse. Our group has shown that donor lymphocyte infusion (DLI) was ineffective for converting <40% donor CD3 chimerism to full donor chimerism. If successful, however, donor CD3 chimerism >90% elicited GVT effects (Blood 2004;103:790). To facilitate effectiveness of DLI for patients (pts) with low or declining donor CD3chimerism, a prospective multicenter trial assessing the safety and efficacy of addingpentostatin was developed. Patients and Met

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Mizuno, Shohei, Luuk Gras, Laurien Baaij, et al. "Impact of Age on Outcome in Newly Diagnosed Multiple Myeloma Patients Undergoing Upfront Autologous Hematopoietic Cell Transplantation from the Worldwide Network for Blood and Marrow Transplantation Global Study." Blood 142, Supplement 1 (2023): 785. http://dx.doi.org/10.1182/blood-2023-179153.

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Background ： Induction therapy with proteasome inhibitors and immunomodulatory agents followed by autologous hematopoietic cell transplantation (HCT) is considered standard of care in front line multiple myeloma (MM) treatment. Utilization of autologous HCT is increasing worldwide in younger and older patients in light of improvements in supportive care and infrastructure. However, global perspectives on patterns of patient age and the impact of age on outcomes in this population are scarce. In the current analysis of global registry data, we focused on the age distribution and the association

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Hays, Michael D., David K. Ryan, and Stephen Pennell. "Multi-Wavelength Fluorescence-Quenching Model for Determination of Cu2+ Conditional Stability Constants and Ligand Concentrations of Fulvic Acid." Applied Spectroscopy 57, no. 4 (2003): 454–60. http://dx.doi.org/10.1366/00037020360626005.

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In this work, a multi-wavelength model (MWM) is developed. It uses fluorescence bands in the fulvic acid (FA) spectrum that quench upon binding of inorganic Cu2+ to FA. Quenching data at pH values of 5, 6, and 7 are placed in sets, containing fluorescence measures at select wavelengths versus added copper ( CM). Intensity data of wavelength set 1 are obtained from 25 nm constant offset synchronous fluorescence spectra (SyF), in which are observed distinct peaks (λex = 415 nm, λem = 440 nm; and λex = 471 nm, λem = 496 nm). Wavelength set 2 intensity data are obtained from the FA fluorescence ex

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Small, Julie A. "Serum mineral concentrations in relation to parturition in beef heifers and cows fed conserved forage." Canadian Journal of Animal Science 77, no. 1 (1997): 63–68. http://dx.doi.org/10.4141/a96-043.

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A study was undertaken to examine the relationship between serum mineral concentrations and calving ease in beef cattle fed conserved forage. Jugular blood samples were taken from multiparous cows (n = 6) and 2-yr-old primparous heifers (n = 9) that calved without assistance and 2-yr-old primparous heifers that required assistance with calving (n = 6) on days −7, 0 and +7 after parturition. Sera were analyzed for Ca, P, Mg, K, S, Na, Cu, Zn and B by ICAP and for progesterone by RIA. From 2 mo before and throughout the calving season cattle were given ad libitum round bale grass-legume silage (

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Bourganou, Maria V., Dimitris C. Chatzopoulos, Daphne T. Lianou, George Th Tsangaris, George C. Fthenakis, and Angeliki I. Katsafadou. "Scientometrics Evaluation of Published Scientific Papers on the Use of Proteomics Technologies in Mastitis Research in Ruminants." Pathogens 13, no. 4 (2024): 324. http://dx.doi.org/10.3390/pathogens13040324.

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The objective of this study was the presentation of quantitative characteristics regarding the scientific content and bibliometric details of the relevant publications. In total, 156 papers were considered. Most papers presented original studies (n = 135), and fewer were reviews (n = 21). Most original articles (n = 101) referred to work involving cattle. Most original articles described work related to the diagnosis (n = 72) or pathogenesis (n = 62) of mastitis. Most original articles included field work (n = 75), whilst fewer included experimental (n = 31) or laboratory (n = 30) work. The ti

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Davies, M. A., A. Y. Bedikian, S. McIntyre, et al. "Natural history of metastatic melanoma patients with CNS metastases." Journal of Clinical Oncology 24, no. 18_suppl (2006): 8054. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.8054.

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8054 Background: Melanoma has a high rate of CNS metastasis (mets). The objective of this study was to evaluate the characteristics and outcomes of melanoma patients (pts) who develop CNS mets. Methods: 333 pts with a diagnosis of CNS mets were identified from databases of 743 chemotherapy naïve metastatic melanoma (MM) pts enrolled on clinical trials between 1986 and 2004. Their clinical and pathological characteristics were reviewed. Results: The site of primary melanoma was head or neck (60/333; 18%), trunk/abdomen (144/333; 43%), limbs (66/333; 20%), ocular (2/333; 1%), or unknown (61/333;

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Shustov, G. V., A. V. Kachanov, I. I. Chervin, R. G. Kostyanovsky та A. Rauk. "Stereochemistry and chiroptical properties of 1,3-dialkylaziridinones (α-lactams). Chiral rules for the nonplanar amide chromophore". Canadian Journal of Chemistry 72, № 2 (1994): 279–86. http://dx.doi.org/10.1139/v94-043.

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Structural features, configurational stability, and chiroptical properties of the nonplanar amide group in α-lactams were investigated by means of ab initio (6-31 + G*) molecular orbital calculations on (1R)-aziridinone 1, (1R)-1-methylaziridinone 2, (1R,3R)-3-methylaziridinone 3, (1R,3R)-1,3-dimethylaziridinone 4a, its cis diastereomer (1S,3R)-1,3-dimethylaziridinone 4b, and (1R,3R)-3-tert-butyl-1-methylaziridinone 5, and by experimental CD spectra of 1-tert-butyl- and 1-(1′-adamantyl)-substituted 3(R)-3-tert-butylaziridinones 6 and 7. The nitrogen inversion barriers of 4a and 4b are 2.8 and

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Szenasi, G., G. Kottra, P. Bencsath, and L. Takacs. "Renal nerves in exaggerated water and sodium excretion by hypertrophied kidney of anesthetized rats." American Journal of Physiology-Renal Physiology 254, no. 1 (1988): F32—F37. http://dx.doi.org/10.1152/ajprenal.1988.254.1.f32.

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The effect of acute renal denervation (RD) on water (V), sodium (UNaV), and potassium excretion (UKV) from the hypertrophied and control kidney was studied in 5-sec-butyl-5-ethyl-2-thiobarbituric acid (Inactin)-anesthetized male rats 7 days after unilateral nephrectomy (Nx) or sham operation (SNx). V, UNaV, and UKV from the hypertrophied kidney were similar before and after RD or sham RD. In contrast, in SNx rats, left RD resulted in an ipsilateral increase in V (from 2.76 +/- 0.39 to 5.31 +/- 0.99 microliters.min-1.g-1), UNaV (from 109 +/- 36 to 857 +/- 331 nmol.min-1.g-1), and UKV (from 144

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Раимкулов, К. М., В. С. Тойгомбаева, О. Т. Куттубаев та А. Э. Мергенов. "КЫРГЫЗ РЕСПУБЛИКАСЫНЫН ОШ ОБЛУСУНУН КАЛКЫНЫН АРАСЫНДА ЭХИНОКОККОЗ ООРУЛАРЫ МЕНЕН ЖАБЫРКАШЫНА ЖАНА ЖҮРҮМ-ТУРУМ ТОБОКЕЛДИК ФАКТОРЛОРУНА БАА БЕРҮҮ". Euroasian Health Journal, № 1 (29 березня 2024): 137–45. http://dx.doi.org/10.54890/ehj-2024-1-137.

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В статье рассмотрены результаты ультразвукового исследования (УЗИ), иммуноферментного анализа (ИФА), исследования на наличие специфических антител, результаты опроса населения 7 районов (8823 человек) и оценки поведенческого фактора риска заражения эхинококкозами населения Ошской области Кыргызской Республики (КР). По результатам ИФА получено 12,0 ± 0,3% (1060) положительных, на УЗИ 8,0 ±0,4% (703). Чаще выявлялась инвазия альвеококкозом как на УЗИ, так на ИФА – 334 (3,78%) и 74,3 ± 0,4% (788) соответственно. Самым эндемичным районом оказался Алайский, где инвазированность обследованных лиц со

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Ball, S. W., J. R. Bailey, J. M. Stewart, C. M. Vogels, and S. A. Westcott. "A fluorescent compound for glucose uptake measurements in isolated rat cardiomyocytes." Canadian Journal of Physiology and Pharmacology 80, no. 3 (2002): 205–9. http://dx.doi.org/10.1139/y02-043.

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A focus of current diabetes research is the development of insulinomimetic compounds for oral treatment of diabetes and its associated cardiac complications. Screening compounds for their potential insulinomimetic effects usually involves the use of radioactive isotopes. The focus of this study was to investigate a nonradioactive fluorescent compound for its use in screening insulinomimetic compounds. The indicator 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) has been used by some workers to measure glucose uptake in Escherichia coli and Candida albicans. We propose t

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Effendy, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXVIII Synthesis and Structural Systematics of Some 1 : 3 Adducts of Silver(I) Compounds with Triphenylstibine, [(Ph3Sb)3AgX], X = Cl, I, SCN, NCS, CN, ONO2." Australian Journal of Chemistry 50, no. 6 (1997): 587. http://dx.doi.org/10.1071/c96035.

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The syntheses and room-temperature single-crystal X-ray structural characterization of 1 : 3 adducts formed between silver(I) (pseudo-) halides, AgX, and triphenylstibine, SbPh3, are described for X = Cl, I, SCN, NCS, CN, NO3 (1)-(6). The chloride, as its methanol solvate (1a), is isomorphous with the arsine analogue: triclinic, P-1, a 13·373(4), b 14·48(6), c 14·702(3) Å, α 83·49(3), β 87·76(2), γ 76·45(3)°; Z = 2, conventional R on F being 0·046 for No 5514 independent ‘observed’ reflections (I > 3σ(I )). A new form (1b) of the chloride has also been authenticated: monoclinic, P 21/c, a 1

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McQuillan, Joseph A., Julia R. Casadio, Deborah K. Dulson, Paul B. Laursen, and Andrew E. Kilding. "The Effect of Nitrate Supplementation on Cycling Performance in the Heat in Well-Trained Cyclists." International Journal of Sports Physiology and Performance 13, no. 1 (2018): 50–56. http://dx.doi.org/10.1123/ijspp.2016-0793.

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Purpose: To determine the effect of consumption on measures of perception, thermoregulation, and cycling performance in hot conditions. Methods: In a randomized, double-blind, crossover design, 8 well-trained cyclists (mean ± SD age 25 ± 8 y, peak 64 ± 5 mL · kg−1 · min−1) performed 2 separate trials in hot (35°C, 60% relative humidity) environments, having ingested either 140 mL -rich beetroot juice ∼8 mmol (NIT) or placebo (PLA) daily for 3 d with a 7-d washout period separating trials. Trials consisted of 2 × 10-min bouts at 40% and 60% peak power output (PPO) to determine physiological and

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CHIANG, M. S., and R. CRETE. "RICHELAIN: A CLUBROOT-RESISTANT CABBAGE CULTIVAR." Canadian Journal of Plant Science 69, no. 1 (1989): 337–40. http://dx.doi.org/10.4141/cjps89-043.

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The Richelain cabbage is a newly released cultivar for the fresh market. It is resistant to races 2, 6 and 7 (Williams 1966) or ECD 16/02/31 and 16/02/30 (Buczacki et al. 1975) of the clubroot pathogen, Plasmodiophora brassicae Wor. Slightly ovate heads with dark blue green crinkly leaves and near white internal color are some other features of this cultivar. The Richelain cabbage cultivar was developed at the Agriculture Canada Research Station, Saint-Jean-sur-Richelieu, Quebec.Key words: Brassica oleracea ssp. capitata, clubroot resistance, crucifers, cabbage cultivar, cultivar description

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Elsawy, N., M. Helal, H. Ashraf Abd Elhamid, and Y. Abdel-Fattah. "AB0731 IMPACT OF FIBROMYALGIA ON DISEASE ACTIVITY INDICES, HEALTH RELATED QUALITY OF LIFE AND FATIGUE IN PATIENTS WITH PSORIATIC ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1659.1–1660. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1509.

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Background:Psoriatic arthritis (PsA), causes inflammation in joints and enthesis, emotional instability and poor quality of life (QOL).1Fibromyalgia (FM) may coexist with PsA, complicating its diagnosis and management.2The effect of FM on the QOL and fatigue in PsA patients has not been vastly studied.3Objectives:Assess the effect of FM on PsA patients’ disease activity indices, QOL and fatigue.Methods:This study included Group I: 37 PsA only patients (61.7%), 48.38 ± 11.69 years and group II: 23 FM-PsA patients (38.3%), 50.78 ± 11.8 years, according to classification criteria for PsA and 2016

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Fuchs, Stephan, Gunter Klohs, Malte Kornhuber, and Rainer Finke. "Klinische Studie: Regenerationspotential der Hautsensibilität nach thermischen Hautschädigungen im Kindesalter." Handchirurgie · Mikrochirurgie · Plastische Chirurgie 51, no. 02 (2018): 119–29. http://dx.doi.org/10.1055/s-0043-121634.

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Zusammenfassung Hintergrund Die Hautsensibilität ist meist zerstört nach tiefgradigen thermischen Hautschädigungen. Die Regeneration der Sinnesempfindung scheint bisher nicht möglich. Methode 31 Kinder mit 338 Hautarealen wurden untersucht und entsprechend ihrer Therapie eingeteilt: Gruppe 1: Nekrosektomie + Spalthauttransplantation, Gruppe 2: epifasziale Nekrosektomie + Spalthauttransplantation, Gruppe 3: epifasziale Nekrosektomie + Integra® + palthauttransplantation. Zur Hauttestung wurden klinisch gebräuchliche Verfahren eingesetzt. Ergebnisse 31 Kinder (3 bis 16 Jahre alt) wurden mit insge

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Chang, Young D., Jae-Woo Jung, Ritika Oberoi-Jassal, et al. "Edmonton Symptom Assessment Scale and Clinical Characteristics Associated With Cannabinoid Use in Oncology Supportive Care Outpatients." Journal of the National Comprehensive Cancer Network 17, no. 9 (2019): 1059–64. http://dx.doi.org/10.6004/jnccn.2019.7301.

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Background: Information about the frequency of cannabinoid use and the clinical characteristics of its users in oncology supportive care is limited. This study explored associations between cannabinoid use and cancer-related clinical characteristics in a cancer population. Patients and Methods: This retrospective review included 332 patients who had a urine drug test (UDT) for tetrahydrocannabinol (THC) together with completion of an Edmonton Symptom Assessment Scale (ESAS) and cannabinoid history questionnaire on the same day that urine was obtained during 1 year in the supportive care clinic

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Ma, Jianhong, Zhenxin Zhu, Xiao Chen, et al. "A cross-sectional survey of nutrition labelling use and its associated factors on parents of school students in Shanghai, China." Public Health Nutrition 21, no. 8 (2018): 1418–25. http://dx.doi.org/10.1017/s1368980018000332.

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AbstractObjectiveTo understand parents’ knowledge and use of nutrition labelling and to explore its associated factors.DesignCross-sectional survey.SettingTwo schools providing a nine-year educational programme in Putuo District, Shanghai, China, were selected for the study. Information was included on demographic data and knowledge of the Chinese Food Pagoda.SubjectsStudents and their parents (n 1770) participated in a questionnaire survey.ResultsOf questionnaires, 1766 were completed (response rate 99·8 %). Utilization rate of nutrition labelling was 19·3 %. Among 624 parents knowing nutriti

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Bowmaker, Graham A., Peter C. Junk, Aaron M. Lee, Brian W. Skelton, and Allan H. White. "Synthetic, Structural and Vibrational Spectroscopic Studies in Bismuth(III) Halide/N,N′-Aromatic Bidentate Base Systems. I Large-Cation (2,2′-Bipyridinium and 1,10-Phenan- throlinium) Salts of Polyhalobismuthate(III) Ions." Australian Journal of Chemistry 51, no. 4 (1998): 293. http://dx.doi.org/10.1071/c97036.

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Syntheses and room-temperature single-crystal X-ray studies are recorded for a variety of salts of cations derived from protonated 2,2′-bipyridine and 1,10-phenanthroline (bpyH+ and phenH+) with polyhalobismuthate(III) anions. ‘[(phenH)(phenH2)(H2O)2] [BiCl6]’ is triclinic, P-1, a 9·791(1), b 9·338(3), c 8·311(3) Å, α 73·46(3), β 69·71(2), γ 86·36(2)°, Z = 1; conventional R on |F| was 0·027 for No 4852 independent ‘observed’ (I > 3σ(I)) reflections. [BiCl6]3- is closely octahedral, accompanied by an interesting protonation/hydrogen-bonding array among the other moieties. The latter comment

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Dang, Yujia, Xiao Huang, Yurong Qin, et al. "Lbl-043, a Novel LILRB4xCD3 T Cell Engager, for the Treatment of Relapsed/Refractory Multiple Myeloma." Blood 144, Supplement 1 (2024): 5827. https://doi.org/10.1182/blood-2024-209139.

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Background: Multiple myeloma (MM) is a clonal plasma cell proliferative disorder characterized by abnormal increase of monoclonal immunoglobulins. Despite newly developed novel therapeutic agents have greatly improved the outcome of MM patients in the past decades, MM is still an incurable hematological malignancy. Several CD3 bispecific immunotherapies that harness T cells against MM are at various stages of preclinical and clinical development, but most of them are hampered by the refractory and drug-resistant mechanisms. Leukocyte immunoglobulin-like receptor B4 (LILRB4) is an immune checkp

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Schlack, Katrin, Andres Jan Schrader, Laura-Maria Krabbe, Karoline Kannen, Axel Semjonow, and Martin Boegemann. "Prediction of outcome in bone metastatic, castration-resistant prostate-cancer-patients under enzalutamide by combining biomarkers." Journal of Clinical Oncology 36, no. 6_suppl (2018): 334. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.334.

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334 Background: Under early Enzalutamide (Enza) treatment of bone mCRPC (bmCRPC), prostate-specific antigen (PSA) might be misleading, since a PSA-flare may occur. Bouncing of alkaline phosphatase (APB) was shown as a promising surrogate for survival outcome. Low lactate dehydrogenase (LDH) usually predicts better outcome. The purpose of this study was to evaluate the prognostic ability of APB, LDH, PSA and information of the pooled markers after initiation of Enza. Methods: 89 bmCRPC-patients were analyzed. PSA, LDH and AP were monitored at 2, 4, 8, 12 and 20 weeks. APB was defined as an incr

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Adkoli, Anusha, Krystle Vera, Patrick Glennan, et al. "Participation of patients with gynecological cancer in phase 1 clinical trials: Experience from 2 NCI-Designated Comprehensive Cancer Centers." Journal of Clinical Oncology 42, no. 16_suppl (2024): e17610-e17610. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e17610.

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e17610 Background: Phase 1 trials are intended to define the safety of novel therapeutics, yet they offer alternate options long before they are approved. There is limited data regarding access and participation in phase 1 trials for gynecologic oncology patients. The purpose of this study is to assess the efficacy of phase 1 trials and to study factors of demographics, tumor characteristics, and toxicities impacting this population group. Methods: This IRB approved study was conducted via retrospective chart review at the Rutgers Cancer Institute of New Jersey and the Montefiore Einstein Comp

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Zimmerman, Molly, Christiane Hale, Adam Brickman, Lok-Kin Yeung, Justin Cochran, and Marie-Pierre St-Onge. "043 Sleep Restriction Affects Memory in Healthy Adults: Preliminary Findings." Sleep 44, Supplement_2 (2021): A18—A19. http://dx.doi.org/10.1093/sleep/zsab072.042.

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Abstract Introduction Sleep loss has a range of detrimental effects on cognitive ability. However, few studies have examined the impact of sleep restriction on neuropsychological function using an experimental design. The goal of this study was to examine the extent to which maintained insufficient sleep affects cognition in healthy adults compared to habitual adequate sleep. Methods This study used a randomized, crossover, outpatient sleep restriction design. Adults who regularly slept at least 7 h/night, verified by 2 weeks of screening with actigraphy, completed 2 phases of 6 weeks each: ha

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Effendy, Warren J. Grigsby, Robert D. Hart, Colin L. Raston, Brian W. Skelton, and Allan H. White. "Structural Characterization of Some Novel Oxidation Products of Triphenylstibine." Australian Journal of Chemistry 50, no. 6 (1997): 675. http://dx.doi.org/10.1071/c96042.

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Room-temperature single-crystal X-ray structural characterizations of two oxidation products of triphenylstibine of the form XPh3SbOSbPh3X are recorded for X = Cl, NO3. ClPh3SbOSbPh3Cl is monoclinic, P 21/c, Z = 4 f.u., a 9·109(4), b 19·809(8), c 19·30(2) Å, β 109·27(5)°, conventional R on F being 0·038 for No 4431 ‘observe’ (I > 3σ(I)) independent reflections. In this complex, Sb-O-Sb is quasi-linear, 173·1(3)°, in contrast to the previously recorded benzene solvate, in which it is 139·0(3)°; in the nitrate, [(O2NO)Ph3SbOSbPh3(ONO2)], triclinic, P-1, Z = 2 f.u., a 15·609(5), b 13·238(4), c

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البدري, نعيم سلمان. "أبو معاذ النحويّ ت211هـ , أخباره وآراؤه". لارك 1, № 12 (2019): 79–109. http://dx.doi.org/10.31185/lark.vol1.iss12.843.

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هو أبو معاذ الفضل بن خالد النحويّ ([i]), يُذْكَرُ باسم الفضل بن خالد ([ii]), وأبي معاذ النحويّ ([iii]),وأبي معاذ الفضل بن خالد ([iv]),وأبي معاذ الفضل بن خالد النحويّ ([v]), ونحو ذلك , وعرف بالمَرْوَزِيِّ ([vi]), والباهليّ ([vii]), ونعته القفطيّ ت624هـ بالمقرئ اللغويّ ([viii]), وقال عنه ابن حبّان ت354هـ:" مولى باهلة "([ix]), فهو إذن باهليّ بالولاء , ونعته المزّيّ ت742هـ بالنحويّ البلخيّ وتابعه الذهبيّ ت748هـ ([x]), ولعلّ نعته بـ ( البلخيّ ) سهو من المزّيّ أو سبق قلم ؛ لأنّه ذكره قبل ذلك ونعته بالنحويّ المَرْوَزِيِّ ([xi]) ؛ ولأنّه عرف بالمَرْوَزِيِّ كثيرا ([xii]), كما أنّ الذهبيّ نفسه قد نعته ح

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البدري, نعيم سلمان. "أبو معاذ النحويّ ت211هـ , أخباره وآراؤه". لارك 1, № 13 (2019): 79–109. http://dx.doi.org/10.31185/lark.vol1.iss13.840.

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هو أبو معاذ الفضل بن خالد النحويّ ([i]), يُذْكَرُ باسم الفضل بن خالد ([ii]), وأبي معاذ النحويّ ([iii]),وأبي معاذ الفضل بن خالد ([iv]),وأبي معاذ الفضل بن خالد النحويّ ([v]), ونحو ذلك , وعرف بالمَرْوَزِيِّ ([vi]), والباهليّ ([vii]), ونعته القفطيّ ت624هـ بالمقرئ اللغويّ ([viii]), وقال عنه ابن حبّان ت354هـ:" مولى باهلة "([ix]), فهو إذن باهليّ بالولاء , ونعته المزّيّ ت742هـ بالنحويّ البلخيّ وتابعه الذهبيّ ت748هـ ([x]), ولعلّ نعته بـ ( البلخيّ ) سهو من المزّيّ أو سبق قلم ؛ لأنّه ذكره قبل ذلك ونعته بالنحويّ المَرْوَزِيِّ ([xi]) ؛ ولأنّه عرف بالمَرْوَزِيِّ كثيرا ([xii]), كما أنّ الذهبيّ نفسه قد نعته ح

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46

Hein, Frances J., James P. M. Syvitski, Lynda A. Dredge, and Bernard F. Long. "Quaternary sedimentation and marine placers along the North Shore, Gulf of St. Lawrence." Canadian Journal of Earth Sciences 30, no. 3 (1993): 553–74. http://dx.doi.org/10.1139/e93-043.

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Offshore areas, along the North Shore of the St. Lawrence Estuary, have major lithostratigraphic and seismostratigraphic units that relate to the advance or retreat of the Late Wisconsinan Ice Sheet, subsequent marine transgression or regression, and reworking of postglacial deposits. Glacial diamicton and glaciomarine units (acoustic units 1 and 2) were emplaced between >18 and 14.5 ka, by basal meltout or ice-marginal sedimentation; they reflect ice-proximal sedimentation associated with ice-terminal stillstands. Deep-water muds (acoustic unit 3) represent ice-distal accumulation of glaci

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Фардеева, Марина Борисовна, та Наталия Андреевна Котова. "ОСОБЕННОСТИ ДИНАМИКИ ПОПУЛЯЦИЙ ДЕРЕВЬЕВ В УСЛОВИЯХ ОПОЛЗНЕВО-ОСЫПНЫХ СКЛОНОВ ПРАВОБЕРЕЖЬЯ РЕКИ ВОЛГИ". Российский журнал прикладной экологии, № 2 (26 червня 2023): 4–17. http://dx.doi.org/10.24852/2411-7374.2023.2.04.17.

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Мониторинг состояния растительности и биоразнообразия флоры в склоновых сообществах правобережья р. Волги и Куйбышевского водохранилища позволяют оценить степень активности/устойчивости экзогенных процессов на данных участках и предупредить риски возникновения новых. В работе представлены результаты исследования лесных сообществ в 2008–2022 гг. на устойчивом, временно-стабильном и активном оползневых склонах и поиски эффективных методов фитоиндикации для оценки их состояния. Определение сукцессионых серий фитоценозов по элементам оползня позволили выявить демутационно-дегрессивные ряды растите

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Da Silva, Érica Beatriz Portela, Andréia Machado Da Silva, Joao Pedro Carvalho Lopes Da Silva, and Valéria Raquel Alcantara Barbosa. "Atuação do psicólogo na rede de proteção junto a famílias com histórico de abuso sexual infantil." Brazilian Journal of Health Review 6, no. 2 (2023): 4995–5013. http://dx.doi.org/10.34119/bjhrv6n2-043.

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RESUMOIntrodução: O abuso sexual infantil é um fenômeno universal, complexo, polissêmico e controverso, de ampla magnitude, que atinge milhares de crianças silenciosamente, provocando graves danos à saúde, ao longo do processo de desenvolvimento, e dificultando as relações interpessoais familiares e sociais. Assim, requer enfoque na perspectiva da Rede, para a garantia da promoção do acolhimento e do cuidado com sentido eminentemente integral, tendo o psicólogo como integrante e protagonista Objetivo: Conhecer a atuação do psicólogo na rede de proteção junto a famílias com histórico de abuso s

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Huyen Trang, Dinh Thi, Pham Hung Viet, Duong Hong Anh, et al. "Lignans and Other Compounds From the Roots of Pandanus tonkinensis and Their Lipid Peroxidation Inhibitory Activity." Natural Product Communications 17, no. 4 (2022): 1934578X2210883. http://dx.doi.org/10.1177/1934578x221088372.

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A new phenylpropane (1) and 9 known (2-10) compounds were isolated from the methanol extract of Pandanus tonkinensis roots. Their chemical structures were determined as (7 S)-2,6-dimethoxyphenyl-7,9-propanediol-1 -O-β-D-glucopyranoside (1), isorhapontigenin (2), pinoresinol-4,4′-di -O-β-D-glucoside (3), isoeucommin A (4), pinoresinol-4′ -O-β-D-glucoside (5), acanthoside B (6), eucommin A (7), urolignoside (8), benzyl O-α-L-arabinopyranosyl-(1→6) -β-D-glucopyranoside (9), and (6 S,9 S)-roseoside (10) by comprehensive analysis of high-resolution electron spray ionization mass spectrum and nuclea

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Fatema, K., S. S. U. Ahmed, M. M. Mukul, A. Sultana, and N. Akter. "GERMINATION OF JUTE GENOTYPES UNDER SALINITY STRESS." Malaysian Journal of Sustainable Agriculture 8, no. 1 (2024): 45–52. https://doi.org/10.26480/mjsa.01.2024.45.52.

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More than 20% of agricultural land around the world is suffering from salt stress which hampers plant growth and development. Jute is one of the most important fiber crops that stands second after cotton in the world. Since cultivable land in Bangladesh is decreasing day by day, jute cultivation needs to be moved to the coastal area. Therefore, the aim of our study was to investigate the response of five jute genotypes at different levels of salinity. Germination and seedling growth were focused on as the most critical stages of plant development. In this research, germination percentage (GP),

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