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1

Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a
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Zhong, Hong Hai, Ji Gui Cheng, Xing Qin Liu, and Guang Yao Meng. "Preparation and Electrical Properties of Interconnect Material Made by Substituting Mixed Rare Earth Oxides (Sm2O3, Gd2O3, Eu2O3 and CeO2) for La2O3 in La." Key Engineering Materials 336-338 (April 2007): 448–51. http://dx.doi.org/10.4028/www.scientific.net/kem.336-338.448.

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La1-xCaxCrO3 (0.1≤ x ≤ 0.4) is usually used as interconnect material for solid oxide fuel cells (SOFCs). In this paper, composite material, the two-phase mixtures of face-centered cubic fluorite structure CayCe1-yO2-y (0 ≤ y≤ 0.2) and orthorhombic perovskite structure [Sm(Eu,Gd)]1-zCazCrO3 (0 < z < 0.3), was prepared by an auto-ignition process in which mixed rare earth oxides (Sm2O3, Gd2O3, Eu2O3 and CeO2) are substituted for La2O3 in La1-xCaxCrO3. The direct current (DC) four-probe technique measurement indicated that the electrical conductivities of specimens increased along with the
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3

Demb, Joshua, Linn Abraham, Diana L. Miglioretti, et al. "Screening Mammography Outcomes: Risk of Breast Cancer and Mortality by Comorbidity Score and Age." JNCI: Journal of the National Cancer Institute 112, no. 6 (2019): 599–606. http://dx.doi.org/10.1093/jnci/djz172.

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Abstract Background Potential benefits of screening mammography among women ages 75 years and older remain unclear. Methods We evaluated 10-year cumulative incidence of breast cancer and death from breast cancer and other causes by Charlson Comorbidity Index (CCI) and age in the Medicare-linked Breast Cancer Surveillance Consortium (1999–2010) cohort of 222 088 women with no less than 1 screening mammogram between ages 66 and 94 years. Results During median follow-up of 107 months, 7583 were diagnosed with invasive breast cancer and 1742 with ductal carcinoma in situ; 471 died from breast canc
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4

Putra, Andika Bagus Nur Rahma, Azizatus Zahro, Harits Ar Rosyid, and Wiwik Wahyuni. "DISEMINASI MESIN PASTEURISASI SUSU DENGAN TEMPERATURE DETECTOR SENSOR UNTUK MENINGKATKAN INCOME DAN BRANDING KAMPUNG SUSU DI DESA PAGERSARI." Jurnal Graha Pengabdian 4, no. 4 (2022): 332. http://dx.doi.org/10.17977/um078v4i42022p332-339.

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Abstrak: Indonesia saat ini sedang melakukan pembangunan dalam berbagai aspek salah satunya melalui program-program pengembangan desa. Salah satu desa yang memiliki potensi dengan prospek yang sangat potensial adalah Desa Pagersari yang berlokasi di Kecamatan Ngantang, Kabupaten Malang. Pagersari memiliki potensi desa yang sangat melimpah berupa susu segar. Di Desa Pagersari terdapat 675 peternak sapi perah. Dalam satu hari total susu yang dipanen dari seluruh peternak sapi mencapai 25 ton. Metode yang digunakan dalam kegiatan ini yaitu metode demonstrasi serta sosialisasi. Kegiatan sosialisas
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5

Loera-Gallardo, Jesus, Juan F. Luna-Salas, and G. A. P. Gibson. "First report of pupal parasitoids of filth-breeding flies (Diptera) from bovine manure in northeastern Mexico." Canadian Entomologist 140, no. 6 (2008): 682–89. http://dx.doi.org/10.4039/n08-043.

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AbstractA total of 2702 individuals representing nine species of Pteromalidae (Chalcidoidea) plus at least one species of Diapriidae, Trichopria haematobiae (Ashmead) (Diaprioidea), were reared as pupal parasitoids of filth-breeding flies in bovine manure during a 2-year study in northern Tamaulipas, Mexico. The Pteromalidae included two undescribed species of Spalangia Latreille plus Spalangia cameroni Perkins, S. drosophilae Ashmead, S. endius Walker, S. nigroaenea Curtis, Muscidifurax raptor Girault and Sanders, M. zaraptor Kogan and Legner, and Pachycrepoideus vindemiae (Rondani). Spalangi
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6

Yazdani, H., H. Rahmani, M. Edris, and E. Dirandeh. "158. EFFECT OF A59V LOCUS IN THE LEPTIN GENE ON LENGTH OF PREGNANCY IN IRANIAN HOLSTEIN COWS." Reproduction, Fertility and Development 21, no. 9 (2009): 76. http://dx.doi.org/10.1071/srb09abs158.

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We investigated effect of A59V polymorphism in the leptin gene on length of pregnancy. Blood was collected from 255 Holstein cattles belonging to four different herd managements in Isfahan province. Genomic DNA extracted from whole blood. Genotypes of A59V locus were identified PCR-RFLP technique. Amplified region is located in exon three of leptin gene. The genomic bovine leptin sequences, which consist of three exons, were obtained from Gene Bank (Accession number U50365). The polymerase chain reaction was used to amplify the 331 bp DNA fragments from genomic DNA. The PCR reaction contained
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7

Diep, Sally, Daiva Daugelaite, Anatoliy Strybulevych, Martin Scanlon, John Page, and Dave Hatcher. "Use of ultrasound to discern differences in Asian noodles prepared across wheat classes and between varieties." Canadian Journal of Plant Science 94, no. 3 (2014): 525–34. http://dx.doi.org/10.4141/cjps2013-043.

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Diep, S., Daugelaite, D., Strybulevych, A., Scanlon, M., Page, J. and Hatcher, D. 2014. Use of ultrasound to discern differences in Asian noodles prepared across wheat classes and between varieties. Can. J. Plant Sci. 94: 525–534. Nine wheat varieties, five Canada Western Red Spring (CWRS) and four Canada Prairie Spring Red (CPSR), grown at the same locations and composited by variety, were milled to yield 65% extraction flours, which were used to form yellow alkaline raw and cooked noodles. The CWRS flours were ∼2% higher in protein content than the CPSR varieties, with varieties within each
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8

Jacoby, Meagan A., Laura E. Finn, Ashkan Emadi, et al. "Post-Marketing Observational Study to Assess the Incidence of Infusion-Related Reactions in Adult Patients with Therapy-Related Acute Myeloid Leukemia (AML) or AML with Myelodysplasia-Related Changes Who Were Treated with CPX-351." Blood 136, Supplement 1 (2020): 19. http://dx.doi.org/10.1182/blood-2020-136880.

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Introduction: CPX-351 (Vyxeos®; daunorubicin and cytarabine liposome for injection), a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a synergistic 1:5 molar ratio, has been approved by the US FDA and EMA for the treatment of adults with newly diagnosed, therapy-related AML or AML with myelodysplasia-related changes. The primary endpoint analysis of the pivotal phase 3 study (NCT01696084) that formed the basis for the approvals evaluated older patients with newly diagnosed high-risk/secondary AML; after a median follow-up of 20.7 months, CPX-351 significantly improved medi
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9

Balboni, Michael J., Adam Sullivan, Adaugo Amobi, et al. "Why Is Spiritual Care Infrequent at the End of Life? Spiritual Care Perceptions Among Patients, Nurses, and Physicians and the Role of Training." Journal of Clinical Oncology 31, no. 4 (2013): 461–67. http://dx.doi.org/10.1200/jco.2012.44.6443.

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Purpose To determine factors contributing to the infrequent provision of spiritual care (SC) by nurses and physicians caring for patients at the end of life (EOL). Patients and Methods This is a survey-based, multisite study conducted from March 2006 through January 2009. All eligible patients with advanced cancer receiving palliative radiation therapy and oncology physician and nurses at four Boston academic centers were approached for study participation; 75 patients (response rate = 73%) and 339 nurses and physicians (response rate = 63%) participated. The survey assessed practical and oper
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10

Fuchs, Stephan, Gunter Klohs, Malte Kornhuber, and Rainer Finke. "Klinische Studie: Regenerationspotential der Hautsensibilität nach thermischen Hautschädigungen im Kindesalter." Handchirurgie · Mikrochirurgie · Plastische Chirurgie 51, no. 02 (2018): 119–29. http://dx.doi.org/10.1055/s-0043-121634.

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Zusammenfassung Hintergrund Die Hautsensibilität ist meist zerstört nach tiefgradigen thermischen Hautschädigungen. Die Regeneration der Sinnesempfindung scheint bisher nicht möglich. Methode 31 Kinder mit 338 Hautarealen wurden untersucht und entsprechend ihrer Therapie eingeteilt: Gruppe 1: Nekrosektomie + Spalthauttransplantation, Gruppe 2: epifasziale Nekrosektomie + Spalthauttransplantation, Gruppe 3: epifasziale Nekrosektomie + Integra® + palthauttransplantation. Zur Hauttestung wurden klinisch gebräuchliche Verfahren eingesetzt. Ergebnisse 31 Kinder (3 bis 16 Jahre alt) wurden mit insge
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11

Gui, Anna, Luke Mason, Teodora Gliga, et al. "Look duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD." Development and Psychopathology 32, no. 4 (2020): 1303–22. http://dx.doi.org/10.1017/s0954579420000930.

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AbstractIdentifying developmental endophenotypes on the pathway between genetics and behavior is critical to uncovering the mechanisms underlying neurodevelopmental conditions. In this proof-of-principle study, we explored whether early disruptions in visual attention are a unique or shared candidate endophenotype of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). We calculated the duration of the longest look (i.e., peak look) to faces in an array-based eye-tracking task for 335 14-month-old infants with and without first-degree relatives with ASD and/or AD
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12

McLeod, Graeme, Iain Kennedy, Eilidh Simpson, Judith Joss, and Katriona Goldmann. "Pilot Project for a Web-Based Dynamic Nomogram to Predict Survival 1 Year After Hip Fracture Surgery: Retrospective Observational Study." Interactive Journal of Medical Research 11, no. 1 (2022): e34096. http://dx.doi.org/10.2196/34096.

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Background Hip fracture is associated with high mortality. Identification of individual risk informs anesthetic and surgical decision-making and can reduce the risk of death. However, interpreting mathematical models and applying them in clinical practice can be difficult. There is a need to simplify risk indices for clinicians and laypeople alike. Objective Our primary objective was to develop a web-based nomogram for prediction of survival up to 365 days after hip fracture surgery. Methods We collected data from 329 patients. Our variables included sex; age; BMI; white cell count; levels of
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13

Krivosheev, G. Ya, and A. S. Ignatiev. "Combining ability of new maize lines according to grain productivity and its components." Grain Economy of Russia, no. 5 (November 12, 2024): 33–39. http://dx.doi.org/10.31367/2079-8725-2024-94-5-33-39.

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The most important indicator of the initial material’s value in breeding for heterosis is its combining ability. The purpose of the current work was to study the combining ability of new self-pollinated maize lines according to grain productivity and its main components. The study was conducted at the FSBSI “ARC “Donskoy”, located in the southern part of the Rostov region with unstable moisture, in 2021–2023. The objects of the studies were 9 new constant self-pollinated maize lines and the line ‘RD 329’, used as a standard. The objects of the studies were also 3 testers, simple maize hybrids
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14

Phillips, Elizabeth H., Amy A. Kirkwood, Christina Hague, et al. "Bleomycin Affects Lung Function for at Least 5 Years after Treatment for Hodgkin Lymphoma - Data from the International, Randomised Phase 3 Rathl Trial." Blood 142, Supplement 1 (2023): 612. http://dx.doi.org/10.1182/blood-2023-185818.

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Introduction: Bleomycin has been an integral part of classical Hodgkin lymphoma (HL) treatment for decades but carries significant toxicity. In particular, acute bleomycin-related lung toxicity occurs in a minority of patients (pts) but has mortality rates as high as 25%. The long-term effects of bleomycin in HL and its impact on lung function are not well known and there is no established guidance for lung screening. The aim of this analysis was to evaluate the impact of bleomycin dose on lung function up to 5 years after treatment in pts recruited to the international, phase 3 RATHL trial. M
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15

Hussain, Syed A., Simon Gomberg, Cairine Probert, Bethan Hickerton, Richard Jackson, and Robin Weston. "Thrombo-embolic events (TEE) during neoadjuvant chemotherapy for muscle invasive bladder cancer." Journal of Clinical Oncology 35, no. 6_suppl (2017): 339. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.339.

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339 Background: Patients with muscle invasive bladder cancer receiving neo-adjuvant chemotherapy (NAC) prior to radical cystectomy or organ preservation treatment are at higher risk of thrombo-embolic events (TEE). Methods: Retrospective data were collected on patients undergoing NAC prior to radical treatment who had surveillance CT scan chest abdomen pelvis following NAC to assess for response or underwent scan following clinical presentation during NAC requiring imaging. The aim of this study was to document the incidence and characteristics of TEE during NAC prior to radical treatment. Res
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Simpson, Mindy, Sanjay Ahuja, Despina Tseneklidou-Stoeter, and Shadan Lalezari. "Extended Interval Prophylaxis with Bay 94-9027 for > 4 Years Leads to Median Spontaneous Annualized Bleeding Rates < 1 in the Protect VIII Extension." Blood 132, Supplement 1 (2018): 1189. http://dx.doi.org/10.1182/blood-2018-99-114619.

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Abstract Introduction: BAY 94-9027 is a B-domain-deleted recombinant factor VIII (FVIII) that is site-specifically PEGylated with a 60-kDa (2 × 30-kDa) polyethylene glycol (PEG) to extend its half-life. The efficacy and safety of BAY 94-9027 as prophylactic and on-demand therapy for patients with severe hemophilia A were demonstrated in the phase II/III PROTECT VIII trial. This analysis provides an updated assessment of the frequency of spontaneous bleeds with BAY 94-9027 prophylaxis during the PROTECT FVIII trial and its extension of more than 4 years. Methods: PROTECT VIII was a partially ra
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17

Widarsih, Rina Eko, Rahma Widyana, and Siti Noor Fatmah Lailatusifah. "The Effectiveness of Self-Induced Unclassified Therapeutic Tremor for Decreasing Secondary Traumatic Stress among Social Workers." Jurnal Psikologi 20, no. 1 (2021): 75–94. http://dx.doi.org/10.14710/jp.20.1.75-94.

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Secondary traumatic stress symptoms are marked by the emergence of traumatic memories experienced by otherpeople, rejection of the stimulus that triggers traumatic memories, and emotional turmoil. If left untreated, it maylower the quality of service and health of social workers. To lower secondary traumatic stress symptoms, it isnecessary to deliver psychological treatment that can be easily and independently done, is effective and cost-efficient, and universal. As such, Therapeutic Tremor Exercises through Self-Induction are consideredappropriate to respond to this need. This study aims to i
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Voong, Khinh Ranh, Benjamin Farnia, Qianghu Wang, et al. "Gamma knife stereotactic radiosurgery in the treatment of brainstem metastases: The MD Anderson experience." Neuro-Oncology Practice 2, no. 1 (2015): 40–47. http://dx.doi.org/10.1093/nop/npu032.

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Abstract Background Brainstem metastases (BSMs) represent a significant treatment challenge. Stereotactic radiosurgery (SRS) is often used to treat BSM. We report our experience in the treatment of BSM with Gamma Knife SRS (GK_SRS). Methods The records of 1962 patients with brain metastases treated with GK_SRS between 2009 and 2013 were retrospectively reviewed. Seventy-four patients with 77 BSMs and follow-up brain imaging were identified. Local control (LC), overall survival (OS), progression-free survival (PFS), and toxicity were assessed. Results Median follow-up was 5.5 months (range, 0.2
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Gilbert, Duncan Charles, Khin Thway, Ian Chandler, et al. "Prediction of relapse in stage I nonseminomatous germ cell tumors (NSGCT) by CXCL12: Results from the MRC TE08 and TE22 clinical trials." Journal of Clinical Oncology 31, no. 6_suppl (2013): 319. http://dx.doi.org/10.1200/jco.2013.31.6_suppl.319.

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319 Background: Stage I NSGCT harbor occult metastatic disease in up to 50% of patients and undergo surveillance with chemotherapy at relapse or adjuvant treatment with excellent survival but concern around subsequent toxicity. Better prediction of relapse would minimize exposure to unnecessary treatments. Previous data suggested CXCL12 aided assessment of relapse risk (Gilbert DC, et al. J Pathol. 2009 Jan;217:94-102). MRC TE08 (Rustin GJ, et al. J Clin Oncol. 2007 Apr 10;25:1310-1315) and TE22 (Huddart RA, et al. J Clin Oncol. 2007 Jul 20;25:3090-3095) were clinical trials incorporating surv
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20

Ervin, M. G., R. Castro, D. J. Sherman, et al. "Ovine fetal renal and hormonal responses to changes in plasma epinephrine." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 260, no. 1 (1991): R82—R89. http://dx.doi.org/10.1152/ajpregu.1991.260.1.r82.

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Circulating epinephrine alters atrial natriuretic factor (ANF) and arginine vasopressin (AVP) secretion, and all three hormones influence renal function. To quantify the relationships among fetal plasma epinephrine levels, fetal ANF and AVP secretion, and fetal renal function, six chronically catheterized fetal lambs (132 +/- 1 days gestation) received successive 40-min epinephrine infusions (0.1, 0.4, and 1.8 micrograms.min-1.kg-1). The second epinephrine infusion dose evoked significant increases in urine flow (V; 0.7 +/- 0.2 to 1.2 +/- 0.2 ml/min), free water clearance (CH2O; 0.3 +/- 0.1 to
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21

Parthasarathy, Akhila, Antje Arnold, Charles Eberhart, and Eric Raabe. "Abstract 5472: Inhibiting the TET pathway in diffuse midline glioma reduces levels of 5-hydroxymethylcytosine and increases levels of 5-methylcytosine." Cancer Research 82, no. 12_Supplement (2022): 5472. http://dx.doi.org/10.1158/1538-7445.am2022-5472.

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Abstract Diffuse Midline Glioma, DMG, is one of the worst forms of pediatric brain tumors and is associated with a 100% mortality rate. DMG, unlike other types of brain tumors, exists in a hypomethylated epigenetic state. In this study, we investigate the contribution of the Ten Eleven Translocation (TET) enzymes towards this unique epigenetic landscape. The TET enzymes which reduce 5methylcytosine (5mC) to 5hydroxymethylcytosine (5hmC) are essential for removing the methylation marks in the genome. In our previous studies, we saw that there is an increased TET expression in DMG, while 5hmC wa
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Baeza-Trinidad, Ramón, and José Daniel Mosquera-Lozano. "Safety of SGLT2 inhibitors in very elderly diabetic type 2 patients in real life." Iberoamerican Journal of Medicine 5, no. 3 (2023): 118–22. http://dx.doi.org/10.53986/ibjm.2023.0023.

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Introduction: Sodium glucose cotransporter 2 inhibitors (SGLT2i) are the latest antidiabetic treatments that reduces mortality and cardiovascular outcomes. Its use in real life in very elderly patients is limited by its possible side effects. Material and methods: We conducted a retrospective study of patients treated with SGLT2i in our community (La Rioja) since 2014. The safety (adverse effects) and prognosis (mortality, cardiac decompensation, and cardiovascular events) during the first 24 months of treatment were evaluated. Results: We included 235 patients treated with SGLT2i, 114 of them
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Bliskunov, A. I., M. G. Le’kin, S. A. Jumabekov, et al. "Lengthening of Femur by Bliskunov Device Using Application of Different Types of Osteotomies." N.N. Priorov Journal of Traumatology and Orthopedics 3, no. 3 (1996): 22–30. http://dx.doi.org/10.17816/vto101786.

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One hundred fifty two patients underwent lengthening of 174 femurs with fully implanted guided device inwhich patients muscular energy was used as a source of energy. Dissection of bone from the side of bone marrow canal was carried out by specially eleborated osteotome which provided transverse oblique, oblique transverse, Z-shape strraight and Z-shape oblique osteotomy. Transverse osteotomy was applied in 59 patients (33.9%), oblique - in 70 (40,6%), oblique transverse - in 26 (14.9%) patients. Distraction stage was completed in all patients. In 165 (94.8%) out of 174 cases planned volume le
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Lombardi, Andrea, Davide Mangioni, Dario Consonni, et al. "Seroprevalence of anti-SARS-CoV-2 IgG among healthcare workers of a large university hospital in Milan, Lombardy, Italy: a cross-sectional study." BMJ Open 11, no. 2 (2021): e047216. http://dx.doi.org/10.1136/bmjopen-2020-047216.

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ObjectivesTo assess the seroprevalence of anti-SARS-CoV-2 IgG among health careworkers (HCWs) in our university hospital and verify the risk of acquiring the infection according to work area.DesignCross-sectional study.SettingMonocentric, Italian, third-level university hospital.ParticipantsAll the employees of the hospital on a voluntary base, for a total of 4055 participants among 4572 HCWs (88.7%).Primary and secondary outcome measuresNumber of anti-SARS-CoV-2 positive serology according to working area. Association of anti-SARS-CoV-2 positive serology to selected variables (age, gender, co
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O'Driscoll, B. Ronan, Louis Kirton, Mark Weatherall, et al. "Effect of a lower target oxygen saturation range on the risk of hypoxaemia and elevated NEWS2 scores at a university hospital: a retrospective study." BMJ Open Respiratory Research 11, no. 1 (2024): e002019. http://dx.doi.org/10.1136/bmjresp-2023-002019.

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BackgroundThe optimal target oxygen saturation (SpO2) range for hospital inpatients not at risk of hypercapnia is unknown. The objective of this study was to assess the impact on oxygen usage and National Early Warning Score 2 (NEWS2) of changing the standard SpO2target range from 94–98% to 92–96%.MethodsIn a metropolitan UK hospital, a database of electronic bedside SpO2measurements, oxygen prescriptions and NEWS2 records was reviewed. Logistic regression was used to compare the proportion of hypoxaemic SpO2values (&lt;90%) and NEWS2 records ≥5 in 2019, when the target SpO2range was 94–98%; w
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Vieira Bento Silva, A. D., M. H. Fernandes Lourenco, S. Ramiro, et al. "POS0678 PERFORMANCE OF CLINICAL, LABORATORY AND IMAGING FEATURES FOR THE DIAGNOSIS OF AXIAL SPONDYLOARTHRITIS - A SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 621.1–621. http://dx.doi.org/10.1136/annrheumdis-2023-eular.108.

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BackgroundThe Berlin algorithm for axial spondyloarthritis (axSpA) diagnosis was developed more than 15 years ago. New evidence suggests that the diagnostic performance of some SpA features might not be as good as initially thought.ObjectivesTo review the evidence on the performance of SpA features for axSpA diagnosis.MethodsSystematic literature review and meta-analysis of studies (2004-2021) reporting data on ≥1 SpA feature. The population was defined as adults (≥16 years) with a suspicion or definite clinical diagnosis of axSpA. The diagnostic performance of each SpA feature was tested agai
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Sierpińska, Lidia Elżbieta, and Monika Domagała. "Assessment of the level of quality of nursing care in an infectious diseases ward." Journal of Education, Health and Sport 12, no. 6 (2022): 296–313. https://doi.org/10.12775/JEHS.2022.12.06.029.

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<strong>Sierpińska Lidia, Domagała Monika</strong><strong>. </strong><strong>Assessment of the level of quality of nursing care in an infectious diseases ward</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 2022;12(6):296-313. eISSN 2391-8306. DOI </strong><strong>https://dx.doi.org/10.12775/JEHS.2022.12.06.029</strong> <strong>https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.06.029</strong> <strong>https://zenodo.org/record/6787424</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>The journal has had 40 points in Ministry of Education and Science of Poland param
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Lorenzi, A. R., A. M. Patterson, A. Pratt, et al. "Corrigendum to “Determination of thymic function directly from peripheral blood: A validated modification to an established method” [J. Immunol. Methods 2008 339(2):185–94]." Journal of Immunological Methods 344, no. 1 (2009): 84. http://dx.doi.org/10.1016/j.jim.2009.03.016.

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29

Kochubey, A. A., and R. Sh Zaremuk. "Study of drought tolerance of hybrid material of home plum in southern Russia." Agrarian science, no. 6 (July 18, 2020): 94–98. http://dx.doi.org/10.32634/0869-8155-2020-339-6-94-98.

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Relevance. The aim of the research was to determine the physiological characteristics of the manifestation of resistance to stress factors (drought) of new hybrid forms of domestic plum and the allocation of the most drought-resistant in the environmental conditions of southern gardening.Methods. The article presents the results of drought tolerance studies of six promising hybrid forms of home plum (17–1-55, 17–1-69, 17–2-64, 17–2-78, 17–2-81, 17–3-79), concentrated in the genetic collection of SKFNTSVV. The main indicators characterizing the varieties and hybrids of home plum were determined
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Abushanan, AlWaleed, Rajashekhara B. Sharanesha, Bader Aljuaid, Tariq Alfaifi, and Abdullah Aldurayhim. "Fracture Resistance of Primary Zirconia Crowns: An In Vitro Study." Children 9, no. 1 (2022): 77. http://dx.doi.org/10.3390/children9010077.

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In this study, we evaluated the fracture resistance of three commercially available prefabricated primary zirconia crowns and their correlation with dimensional variance. Methods: a total of 42 zirconia crowns were selected from three companies, (1) NuSmile primary zirconia crowns, (2) Cheng Crowns zirconia, and (3) Sprig EZ crowns. The crowns were divided into two groups based on their location in the oral cavity and further divided into subgroups based on the brand. All of the samples were subjected to fracture tests using a universal testing machine. Results: the mean load observed was high
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Porceddu, Sandro Virgilio, Michael Poulsen, Mathias Bressel, et al. "Post-operative concurrent chemo-radiotherapy versus post-operative radiotherapy in high-risk cutaneous squamous cell carcinoma of the head and neck: A randomized phase III trial (Trans Tasman Radiation Oncology Group 05.01 Trial; POST study)." Journal of Clinical Oncology 35, no. 15_suppl (2017): 6008. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.6008.

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6008 Background: We report on the first multi-centre randomized phase III trial of post-operative radiotherapy (PORT) vs post-operative chemo-RT (CRT) in high-risk cutaneous squamous cell carcinoma of the head and neck (cSCCHN) (NCT00193895). Methods: The primary objective was to determine whether there was a freedom from loco-regional relapse (FLRR) difference between patients randomly assigned to 60-66Gy (6-6.5 weeks) with or without weekly carboplatin (AUC 2) following resection of gross disease. Patients were stratified to high-risk nodal (either extracapsular nodal extension, intra-paroti
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Nakayama, Y., R. Nakashima, T. Handa, et al. "POS1051 LUNG CLUSTERING ANALYSIS-BASED PHENOTYPES OF RHEUMATOID ARTHRITIS USING ARTIFICIAL INTELLIGENCE-BASED TECHNOLOGY FOR CHEST COMPUTED TOMOGRAPHY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 843.1–844. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2178.

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BackgroundLung involvement is a prevalent extraarticular manifestation of rheumatoid arthritis (RA) that remains a significant clinical challenge. Few studies have comprehensively quantified lung abnormalities of RA patients using artificial intelligence-based (AI) technology.ObjectivesThe aim of this study was to quantify lung lesions in RA patients and classify them based on their lung parameters.MethodsAn AI-based quantitative computed tomography (CT) image analysis software (AIQCT) was applied to high-resolution CT scans of RA patients in a cross-sectional manner. AIQCT automatically class
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Sakhnov, S. N., S. V. Yanchenko, A. V. Malyshev, Z. M. Blyagoz, and G. A. Klimenova. "Dry eye treatment optimization in patients prior to refractive surgery." Russian Ophthalmological Journal 11, no. 4 (2018): 87–95. http://dx.doi.org/10.21516/2072-0076-2018-11-4-87-94.

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Purpose. To evaluate the effectiveness of dry eye syndrome (DES) treatment in patients with meibomian gland dysfunction (MGD) before refractive surgery.Materials and methods. We examined 48 women (aged 29.6 ± 3.9 years) with myopia, DES, and MGD of noninfectious etiology before performing LASIK. Group 1 of these patients received presurgical correction of DES for 2 months, including instillation of 3 % trehalose as a bioprotector (Thealoz®; 3–4 times a day); application of 5 % dexpanthenol in the conjunctival cavity (before going to bed); eyelid hygiene (2 times per day), which included cleani
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Van der Heijde, D., X. Baraliakos, M. Dougados, et al. "OP0019 BIMEKIZUMAB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 2, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO-CONTROLLED STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 12–13. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2441.

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BackgroundBimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits IL-17F in addition to IL-17A. In a phase 2b study, BKZ showed rapid and sustained efficacy and was well tolerated up to 156 weeks (wks) in patients (pts) with active ankylosing spondylitis (AS).1,2ObjectivesTo assess efficacy and safety of BKZ vs placebo (PBO) in pts with active AS up to Wk 24 in the ongoing pivotal phase 3 study, BE MOBILE 2.MethodsBE MOBILE 2 (NCT03928743) comprises a 16-wk double-blind, PBO-controlled period and 36-wk maintenance period. Pts were aged ≥18 yrs, met modified New York criteria
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Pache, Basile, Fabian Grass, Martin Hübner, Amaniel Kefleyesus, Patrice Mathevet, and Chahin Achtari. "Prevalence and Consequences of Preoperative Weight Loss in Gynecologic Surgery." Nutrients 11, no. 5 (2019): 1094. http://dx.doi.org/10.3390/nu11051094.

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Preoperative malnutrition and weight loss negatively impact postoperative outcomes in various surgical fields. However, for gynecologic surgery, evidence is still scarce, especially if surgery is performed within enhanced recovery after surgery (ERAS) pathways. This study aimed to assess the prevalence and impact of preoperative weight loss in patients undergoing major gynecologic procedures within a standardized ERAS pathway between October 2013 and January 2017. Out of 339 consecutive patients, 33 (10%) presented significant unintentional preoperative weight loss of more than 5% during the 6
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Green, H. J., E. R. Chin, M. Ball-Burnett, and D. Ranney. "Increases in human skeletal muscle Na(+)-K(+)-ATPase concentration with short-term training." American Journal of Physiology-Cell Physiology 264, no. 6 (1993): C1538—C1541. http://dx.doi.org/10.1152/ajpcell.1993.264.6.c1538.

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To investigate the effect of short-term training on Na(+)-K(+)-adenosine triphosphatase (ATPase) concentration in skeletal muscle and on plasma K+ homeostasis during exercise, 9 subjects performed cycle exercise for 2 h per day for 6 consecutive days at 65% of maximal aerobic power (VO2 max). Na(+)-K(+)-ATPase concentration determined from biopsies obtained from the vastus lateralis muscle using the [3H]ouabain-binding technique increased 13.6% (P &lt; 0.05) as a result of the training (339 +/- 16 vs. 385 +/- 19 pmol/g wet wt, means +/- SE). Increases in Na(+)-K(+)-ATPase concentration were ac
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Park, Sang Hyun, Taek Sang Kim, Jae Young Joung, Sung Han Kim, and Jinsoo Chung. "Postoperative long-term prognosis of localized renal cell carcinoma after partial or radical nephrectomy: Analysis of cancer metastasis and deaths during a more than five-year follow-up." Journal of Clinical Oncology 37, no. 7_suppl (2019): 604. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.604.

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604 Background: We performed a long-term follow-up study to evaluate the survival and metastatic outcomes of non-metastatic renal cell carcinoma (RCC) after curative removal of tumor. Methods: We retrospectively reviewed the clinical and pathological features of 5434 patients with localized renal cell carcinoma admitted to five Korean tertiary-care institutions between 2000 and 2012, who had undergone curative surgeries with partial or radical nephrectomy with/without lymph nodal dissection. The patients below the age of 19 years (N=9) with benign histology (N=24), and with no follow-up record
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SCHLESINGER, NAOMI, JOSEPHINE M. NORQUIST, and DOUGLAS J. WATSON. "Serum Urate During Acute Gout." Journal of Rheumatology 36, no. 6 (2009): 1287–89. http://dx.doi.org/10.3899/jrheum.080938.

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Objective.To study the frequency of normal serum urate (SU) levels during acute gout in the largest studies of acute gout treatment to date.Methods.Data collected from 2 randomized controlled clinical trials assessing the efficacy of etoricoxib or indomethacin for 7 days in acute gout were used to assess SU levels during acute gouty attacks. Efficacy was similar with both agents, so both groups were combined for analysis.Results.A total of 339 patients were enrolled in the 2 studies; 94% were male; mean age was 50.5 years. At baseline, 14% of patients had a “true” normal SU (≤ 6 mg/dl) and 32%
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Grundy, H. F., R. Hardy, and M. H. Davies. "Effect of level of barley supplementation on the performance of continental × Holstein Friesian bulls given grass silage." Animal Science 58, no. 1 (1994): 35–40. http://dx.doi.org/10.1017/s0003356100007054.

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AbstractForty Charolais and 40 Limousin × Holstein Friesian bulls, 8 months old and weighing 315 kg live weight at the start of the experiment, were given grass silage to appetite throughout.From 315 to 425 kg live weight they received: no supplement (S0), 1 kg (S1), 2 kg (S2) or 4 kg (S4) of a rolled barley supplement per head per day. After a mean treatment live weight of 425 kg had been achieved for each breed, the daily supplement of all treatments was changed to 3 kg of rolled barley per head per day until individual animals were adjudged to have attained a European Community (EC) externa
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Mayet, Soraya, and Shumaila Shahbaz. "Improving attendance in addictions - do quality improvement plans work?" BJPsych Open 7, S1 (2021): S206—S207. http://dx.doi.org/10.1192/bjo.2021.552.

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AimsWe assessed whether a quality improvement plan initiated in 2018 had sustained benefits for improving attendance rates at addiction prescriber reviews, after 13 months.MethodThe QIP re-audit had Humber Teaching NHSFT approval. We assessed electronic healthcare records of patients prescribed OST at a specialist addictions service, spanning a large geographical area, split into three Hubs. Data were analysed via Microsoft excel.Baseline data for the whole addictions service were collected in April 2018 (n = 343), followed by QIP implementation. The QIP included a new appointment letter expla
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Ramirez, Mirta Mesquita, Miria Noemi Zarate, Leonidas Adelaida Rodriguez, and Victor Hugo Aquino. "Performance evaluation of Biofire Film Array Respiratory Panel 2.1 for SARS-CoV-2 detection in a pediatric hospital setting." PLOS ONE 18, no. 10 (2023): e0292314. http://dx.doi.org/10.1371/journal.pone.0292314.

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The highly contagious nature of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19), requires rapid diagnostic tests to prevent the virus from spreading within hospitals and communities. Reverse transcription followed by the polymerase chain reaction (RT-PCR) test is the gold standard for detecting SARS-CoV-2 infections but is time-consuming, labor-intensive, and restricted to centralized laboratories. There is a growing need to develop and implement point-of-care and rapid tests for SARS-CoV-2 detection to address these
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Gallegos-Guajardo, Julia, Norma Ruvalcaba-Romero, Ania Chávez-Amavizca, and Cecilia Martinez-Torteya. "Validation of the Children’s Inventory of Anger (ChIA) with a Mexican sample." Revista de Psicología Clínica con Niños y Adolescentes 9, no. 2 (2022): 49–56. http://dx.doi.org/10.21134/rpcna.2022.09.2.6.

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The Children’s Inventory of Anger (ChIA) is a self-report measure that assesses the level of anger experienced by children and youth. Anger is a significant predictor of aggression, peer relationships difficulties and antisocial behavior; therefore, is crucial to have a valid and reliable measure to evaluate it. The purpose of this study was to validate the ChIA for the Mexican children (ChIA-M). Participants were 638 students (M = 9.8 years; SD = 1.51), 49% were females from primary and secondary Mexican public schools. The exploratory factor analysis supported the four-factor structure with
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Lee, Keun-Wook, Young Suk Park, Joong Bae Ahn та ін. "332 Novel TGF-β signatures in metastatic colorectal cancer patients treated with vactosertib in combination with pembrolizumab". Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A358. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0332.

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BackgroundDual inhibition of transforming growth factor beta (TGF-β) signaling and PD-1 is a promising strategy to reverse immunosuppressive tumor microenvironment and poor responses to immunotherapy. Based on preliminary clinical data with vactosertib, a highly selective and potent inhibitor of TGF-β receptor type 1, in combination with pembrolizumab, this study aimed to explore a biomarker with predictive value for this regimen in metastatic microsatellite stable (MSS) colorectal cancer (CRC).MethodsTumor biopsy samples were obtained from 24 CRC patients at baseline and cycle 2 in the ongoin
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Whittall, Ian R., Mark G. Humphrey, and David C. R. Hockless. "Structural Systematics of Metal Acetylide Complexes: X-Ray Studies of Some 'Extended-Chain' Gold σ-Acetylide Complexes." Australian Journal of Chemistry 50, no. 10 (1997): 991. http://dx.doi.org/10.1071/c97049.

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The structures of Au(4-C≡CC6H4XYC6H4-4′-NO2)(PPh3) (XY = (E )-CH=CH (1), (Z)-CH=CH (2), C≡C (3), N=CH (4)) have been determined by single-crystal X-ray diffraction analyses, refining by full-matrix least-squares analysis. For (1), crystals are triclinic, space group P-1, with a8·847(1), b 17·870(4), c 19·705(3) Å, α116·25(1), β 93·33(1), γ 92·64(2)˚, Z 4, 6747 unique reflections (703 parameters), converging at R 0·025 and Rw 0·029. For (2), crystals are monoclinic, space group P 21/a, with a 10·718(6), b 19·398(5), c14·469(3) Å, β 108·96(2)˚, Z 4, 3295 unique reflections (352 parameters), conv
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Ali, Zahid, Muhammad Rahil Khan, Riyasat Ahmed Memon, Ikram Din Ujjan, Fida Hussain, and Zainab Nisar. "NEGATIVE APPENDECTOMIES ARE MORE COMMON IN FEMALES OF REPRODUCTIVE AGE GROUP." PAFMJ 71, no. 6 (2021): 2011–14. http://dx.doi.org/10.51253/pafmj.v6i6.4630.

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Objective: To compare the negative appendectomy in the females of reproductive and non-reproductive age groups.&#x0D; Study Design: Cross-sectional study.&#x0D; Place and Duration of Study: Department of Pathology, Diagnostic and Research Laboratory, Liaquat University of Medical and Health Sciences, Hyderabad, Pakistan, from January 2018 to December 2019.&#x0D; Methodology: A total of 1126 appendectomy specimens were enrolled irrespective of age and gender. The biodata of patients was retrieved from the database. Statistical analysis was done using SPSS version 22.&#x0D; Results: Out of total
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Lo Coco, Francesco, Giuseppe Avvisati, Marco Vignetti, et al. "Front-Line Treatment of Acute Promyelocytic Leukemia with AIDA Induction Followed by Risk-Adapted Consolidation: Results of the AIDA-2000 Trial of the Italian GIMEMA Group." Blood 104, no. 11 (2004): 392. http://dx.doi.org/10.1182/blood.v104.11.392.392.

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Abstract Following the identification, in collaboration with the Spanish PETHEMA group, of distinct prognostic categories among APL patients receiving AIDA-like therapies (Sanz et al. Blood 2000) the Italian GIMEMA group designed a protocol for newly diagnosed APL (AIDA-2000) in which the intensity of post-remission treatment was adapted to the relapse risk. A total of 298 PML/RARa-positive patients with median age 40 yrs (range 1–60) were enrolled during the period January 2000 – February 2003 from 64 Italian institutions. After the standard AIDA-0493 induction (Mandelli et al, Blood 1997), p
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Osborne, L. D., and Z. Rengel. "Genotypic differences in wheat for uptake and utilisation of P from iron phosphate." Australian Journal of Agricultural Research 53, no. 7 (2002): 837. http://dx.doi.org/10.1071/ar01101.

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Two glasshouse experiments were conducted to evaluate the genotypic variation amongst cereal genotypes in phosphorus uptake from relatively insoluble iron phosphate. Optimum rates of iron phosphate were established by growing 3 wheat and 1 triticale genotype on an infertile sand amended with iron phosphate. Shoot dry weight of all genotypes showed a classic Mitcherlich response with 95% maximum growth achieved with 174�mg P/kg soil. Two rates of FePO4 were selected representing a deficient and sufficient supply (26 and 339 mg P/kg soil, respectively). These rates were used to screen 99 wheat,
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Drozdovska, Olesia. "The little-know Ivan Shlendyk (1889—1946): life and work." Вісник Книжкової палати, no. 10 (December 19, 2024): 35–42. https://doi.org/10.36273/2076-9555.2024.10(339).35-42.

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The article is dedicated to Ivan Shlendyk, one of the little-known representatives of the Ukrainian diaspora in Manchuria, a populariser of the idea of Ukrainian state independence and a chronicler of Ukrainian life in East Asia. The purpose of the research is to highlight I. Shlendyk's biography and to study his socio-communication activities, specifically his collaboration with the Ukrainian press published in the 1930s. The research employs biographical, bibliographical, comparative methods, as well as press clipping, classification, and generalization techniques. The scientific novelty of
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Tin, Derrick, Lenard Cheng, Ryan Hata, Alexander Hart, Attila Hertelendy, and Gregory Ciottone. "A Descriptive Analysis of the Health Care Aspects of Industrial Disasters Around the World." Prehospital and Disaster Medicine 38, S1 (2023): s72—s73. http://dx.doi.org/10.1017/s1049023x23002145.

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Introduction:Industrial disasters can have a myriad of repercussions ranging from acute deaths, injuries, and long-term adverse health impacts on nearby populations to political fallout and environmental damage. This is a descriptive epidemiological analysis of industrial disasters occurring between 1995 and 2021 which may provide useful insight for health care systems and disaster medicine specialists to better prevent and mitigate the effects of future industrial disasters.Method:Data was collected using a retrospective database search of the Emergency Events Database (EM-DATS) for all indus
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Luu, Huong, Gerald Spotts, Hartwig Gajek, et al. "ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin- Free Method] Post-Authorization Safety Surveillance (PASS): Safety and Efficacy Following Product Switch in Routine Clinical Practice." Blood 112, no. 11 (2008): 3375. http://dx.doi.org/10.1182/blood.v112.11.3375.3375.

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Abstract A prospective, non-interventional Post-Authorization Safety Surveillance (PASS) program was initiated in 2004 to document ADVATE safety and efficacy in routine clinical practice. More than 900 subjects newly prescribed ADVATE have been enrolled in the US, EU and Japan alone. Herein, we present final US and interim EU results comprising 506 treated subjects, 451 of which have completed the 1-year observation period and 20 ongoing. Age cohorts were as follows: 27 neonates/infants (0-&lt;2 years), 128 children (2-&lt;12 years), 54 adolescents (12-&lt;16 years), and 285 adults (≥16 years)
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