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Journal articles on the topic '340.12 (043.2)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Herman, J. R., M. T. DeLand, L. K. Huang, et al. "A net decrease in the Earth's cloud plus aerosol reflectivity during the past 33 yr (1979–2011) and increased solar heating at the surface." Atmospheric Chemistry and Physics Discussions 12, no. 12 (2012): 31991–2038. http://dx.doi.org/10.5194/acpd-12-31991-2012.

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Abstract. Measured upwelling radiances from Nimbus-7 SBUV, seven NOAA SBUV/2 and the AURA-OMI instruments have been used to calculate the 340 nm Lambertian Equivalent Reflectivity (LER) of the Earth from 1979 to 2011 after applying a new common calibration. The 340 nm LER is highly correlated with cloud and aerosol cover because of the low surface reflectivity of the land and oceans (typically 2 to 6 RU, where 1 RU = 0.01 = 1.0%) relative to the much higher reflectivity of clouds plus aerosols (typically 10 to 90 RU). Because of the nearly constant seasonal and long-term 340 nm surface reflect

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ESEN, Erol, Barışcan ÖZTÜRK, and Adil KAVAL. "Adaptation of Online Sexual Harassment Scale into Turkish: A Validity And Reliability Study." fe dergi feminist ele 15, no. 1 (2023): 232–57. http://dx.doi.org/10.46655/federgi.1143343.

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Bu çalışmanın amacı, Çevrimiçi Cinsel Taciz Ölçeği’nin Türkçe’ye uyarlamasını gerçekleştirmek, bu kapsamda geçerlik ve güvenirlik çalışmalarını yapmaktadır. Çalışmanın bir diğer amacı ise üniversite öğrencilerinin çevrimiçi cinsel tacize maruz kalmalarının cinsiyete göre farklılık gösterip göstermediğinin incelenmesidir. Çalışmaya 340 üniversite öğrencisi (221 kadın, 119 erkek) katılmıştır. Ölçeğin yapı geçerliğini incelemek amacıyla 340 katılımcıdan elde edilen veri seti ile Doğrulayıcı Faktör Analizi (DFA) yapılmıştır. Ölçeğin orijinalinde olduğu gibi 12 maddeden oluşan 2 faktörlü (cinsel i

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Edwards, Amy, Kevin Percival, Louisa Zouita, Jan Arevalo, and John Philip O'Dwyer. "ANALYSIS OF CONVULSIVE SEIZURES AT A DGH EMERGENCY DEPARTMENT." Journal of Neurology, Neurosurgery & Psychiatry 86, no. 11 (2015): e4.129-e4. http://dx.doi.org/10.1136/jnnp-2015-312379.4.

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IntroductionSeizures represent 3% of all emergency department attendances.MethodsA list of all possible seizure mimics was generated from ED computerized triage systems from 1/1/12 to 31/12/13. Data was extracted manually from review of ED notes and analyzed.Results905 seizure attendances by 636 patients were examined over 2 years. 340 men and 296 women accounted for them, with average age 33±28 years. 245 patients had a history of epilepsy and were taking at least one AED. >2 AEDs were used by 32 patients. 22 had known Non-Epileptic Attacks (NEAD). Convulsive seizures occurred in 429 and S

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Ashor, Ammar W., Mario Siervo, Jose Lara, Clio Oggioni, Sorena Afshar, and John C. Mathers. "Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials." British Journal of Nutrition 113, no. 8 (2015): 1182–94. http://dx.doi.org/10.1017/s0007114515000227.

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Randomised controlled trials (RCT) testing the effects of antioxidant supplements on endothelial function (EF) have reported conflicting results. We aimed to investigate the effects of supplementation with antioxidant vitamins C and E on EF and to explore factors that may provide explanations for the inconsistent results. We searched four databases (MEDLINE, Embase, Cochrane Library and Scopus) from inception until May 2014 for RCT involving adult participants aged ≥ 18 years who were supplemented with vitamins C and E alone or in combination for more than 2 weeks and reporting changes in EF m

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Stilgenbauer, Stephan, Barbara F. Eichhorst, Raymonde Busch, et al. "Biologic and Clinical Markers for Outcome after Fludarabine (F) or F Plus Cyclophosphamide (FC) - Comprehensive Analysis of the CLL4 Trial of the GCLLSG." Blood 112, no. 11 (2008): 2089. http://dx.doi.org/10.1182/blood.v112.11.2089.2089.

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Abstract The CLL4 trial evaluated 1st line treatment with F or FC among 375 CLL patients up to 65 years (Eichhorst et al., Blood, 2006). Updated follow-up (median 52.8 months (mo) for alive patients) revealed 50.4% events for progression-free survival (PFS) and 24.5% for overall survival (OS). Comparing the treatment arms, significant differences were observed in favor of FC for CR (19.9% vs 5.9%, p&lt;.001), CR+PR (94.7% vs 82.4%, p&lt;.001), and PFS (median 67.8 vs 43.7 mo, p=.002) but not for OS (median n.r. vs 84.6 mo, p=.191). The incidences of genomic aberrations by FISH (n=321)

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Lucas, C., S. Rodriguez, R. Jean, et al. "AB0034 EARLY IMMUNIZATION AGAINST TREATMENT IS ASSOCIATED TO POOR CLINICAL RESPONSE AT 6 MONTHS AND LOW NUMBER OF TRANSITIONAL B CELLS AT BASELINE IN RHEUMATOID ARTHRITIS PATIENTS TREATED BY ADALIMUMAB." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1319.1–1320. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3938.

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Background:Circulating anti-drug antibodies (ADAs) are detectable approximatively in 33% of adalimumab treated rheumatoid arthritis (RA) patients, often within the first 6 months of therapy1-2. Classically, circulating ADAs associate with their specific drugs to form immune complexes, increasing drug clearance, and by this mechanism reducing therapeutic effect3. B cell involvement leading to ADAs production is not yet well established.Objectives:To study early ADAs formation according to clinical response to an adalimumab therapy in RA patients and the relationship between ADAs and circulating

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7

Beljaars, Paul R., Remmelt Van Dijk, Eric Bisschop, et al. "Liquid Chromatographic Determination of Free Glutamic Acid in Soup, Meat Product, and Chinese Food: Interlaboratory Study." Journal of AOAC INTERNATIONAL 79, no. 3 (1996): 697–702. http://dx.doi.org/10.1093/jaoac/79.3.697.

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Abstract An interlaboratory study of the liquid chromatographic (LC) determination of free glutamic acid in soup, meat product, and Chinese food was performed. Homogenized food samples were extracted with hot water, filtered, and diluted. Aliquot portions were treated with N,N-dimethyl-2-mer-capto-ethyl-ammonium chloride (DMMAC) and o phtaldialdehyde (OPA) to convert glutamic acid to a stable fluorescent complex. After LC separation on a reversed-phase C18 column with acetonitrile–phosphate buffer (pH 7.O)–water (80 +180 + 740, v/v) as mobile phase, glutamic acid peaks were measured fluorometr

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Fuad, Muhammad, and Muh Kurniawan. "Production of Biodiesel Distillate with Low Monoglycerides for B40 Component by Using Distillation Technique with 1 and 30 Plates Column." IOP Conference Series: Earth and Environmental Science 1034, no. 1 (2022): 012006. http://dx.doi.org/10.1088/1755-1315/1034/1/012006.

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Abstract One of the quality standard indicators for biodiesel (fatty acid methyl ester, FAME) product specifications is monoglyceride content. Monoglycerides (MG) are residuals of the vegetable oil reactant that do not react completely in the process of making biodiesel, so that they become contaminants in biodiesel. The lower the monoglycerides in the biodiesel product, the better the quality of the biodiesel. In Indonesia’s B40 program, one scenario of adding 10% biodiesel is using FAME distillate on top of 30% regular FAME. The monoglyceride content in the FAME distillate for the B40 mixtur

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Minderico, Cláudia S., Analiza M. Silva, Kathleen Keller, et al. "Usefulness of different techniques for measuring body composition changes during weight loss in overweight and obese women." British Journal of Nutrition 99, no. 2 (2008): 432–41. http://dx.doi.org/10.1017/s0007114507815789.

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The objective was to compare measures from dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA) and anthropometry with a reference four-compartment model to estimate fat mass (FM) and fat-free mass (FFM) changes in overweight and obese women after a weight-loss programme. Forty-eight women (age 39.8 ± 5.8 years; weight 79·2 ± 11·8 kg; BMI 30·7 ± 3·6 kg/m2) were studied in an out-patient weight-loss programme, before and after the 16-month intervention. Women attended weekly meetings for the first 4 months, followed by monthly meetings from 4 to 12 months. Body composi

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Aleman, Ricardo S., Dany Avila, Allan Avila, et al. "Chemical Characterization and Impact of Nipple Fruit (Solanum mammosum) on the Characteristics of Lactobacillus acidophilus LA K." Fermentation 9, no. 8 (2023): 715. http://dx.doi.org/10.3390/fermentation9080715.

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Nipple fruit (Solanum mammosum) has been considered to have great pharmaceutical potential because of its high amounts of solamargine and solasonine. This study aimed to examine the effect of nipple fruit at different concentrations (0.5%, 1%, and 2% (w/v)) on the viability, acid, bile, lysozyme, and gastric juice tolerance, and protease activity of Lactobacillus acidophilus LA K. The viability was studied in MRS broth. Acid tolerance was determined by adjusting the pH to 2, whereas bile tolerance was examined with oxgall 0.3% (w/v) in MRS broth. Lysozyme resistance was investigated in an elec

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Dombret, Hervé, Alexandra Coelho, Laurène Fenwarth, et al. "Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study." Blood 144, Supplement 1 (2024): 2424. https://doi.org/10.1182/blood-2024-207226.

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Introduction. AML treatment options have been recently enriched. New agents like gemtuzumab ozogamicin (GO), FLT3 or IDH inhibitors, or CPX-351 have been approved for some patient subsets. Less-intensive options, like the AZA-VEN combination, are used in older/unfit patients. However, while treatments and indications are standardized, their choice is not, depending on often-subjective factors. This makes observational studies so important to describe the real-life management and outcomes of AML patients. Methods. In 2022, the ALFA group initiated a 2-cohort (newly diagnosed, relapsed/refractor

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Cuervo, Wilmer, Camila Gomez Lopez, Ignacio Fernandez Marenchino, et al. "340 Ruminal Protozoa Viability Under Diverse Additives Using Trypan Blue Exclusion Method as an Alternative Counting Methodology." Journal of Animal Science 101, Supplement_3 (2023): 269–70. http://dx.doi.org/10.1093/jas/skad281.322.

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Abstract Beef cattle are a major contributor to methane (CH4) emissions. Enteric CH4 is produced by archaea, mostly hosted by ruminal protozoa, thus, changes in protozoa counts have been associated with CH4 production. Therefore, reliable ruminal protozoa count (PROT) is essential to evaluate CH4-mitigation strategies. Typically, PROT are done by fixation with methyl-green-formalin-saline solution (MFS), which reveals ciliate numbers but not ruminal protozoa viability (VIAB). The Trypan Blue Exclusion Method (TBEM) involves an intracellular probe that dyes the cytoplasm of apoptotic eukaryotic

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Aleman, Ricardo S., Dany Avila, Allan Avila, et al. "Effects of Weevil (Rhynchophorus palmarum), Teosinte (Dioon mejiae) and Caesar’s Mushroom (Amanita caesarea) on the Properties of Lactobacillus acidophilus LA-K." Fermentation 9, no. 9 (2023): 852. http://dx.doi.org/10.3390/fermentation9090852.

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Weevil (Rhynchophorus palmarum) powder, teosinte (Dioon mejiae) and Caesar’s mushroom (Amanita caesarea) flour have bioactive compounds with significant nutritional applications. This paper aimed to examine the influence of weevil, teosinte, and mushroom powders on the protease activity, acid tolerance, bile tolerance, lysozyme tolerance, and gastric juice resistance ability of Lactobacillus acidophilus LA-K. Acid tolerance was determined by adjusting the pH of MRS broth to 2.0 for L. acidophilus incubated under aerobic conditions at 37 °C. Bile tolerance was determined by incorporating 0.3% o

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Bowmaker, Graham A., Effendy, Robert D. Hart, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXIII Synthesis, Spectroscopy and Structural Systematics of New 1 : 1 'Cubane' Tetramers of Copper(I) and Silver(I) Halides with Triphenylarsine." Australian Journal of Chemistry 50, no. 6 (1997): 653. http://dx.doi.org/10.1071/c96039.

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Syntheses and room-temperature single-crystal X-ray structural characterization of a number of 1 : 1 ‘cube tetramer’ adducts of copper(I) and silver(I) halides, MX, with triphenylarsine, AsPh3, are recorded, being [XM(AsPh3)]4. The CuBr adduct, obtained unsolvated from toluene, orthorhombic Pbcn, a 17·844(5), b 20·778(8), c 18·430(4) Å, Z = 4 tetramers, conventional R on |F| 0·058 for No 1309 independent ‘observed’ reflctions (I > 3σ(I)), is isomorphous with previously recorded [ClAg(PPh3)]4, the tetramer having crystallographically imposed 2 symmetry. The CuI adduct, previously recorded as

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Fahmi, Amr Mohamed, Adham Mohamed, Hazem Elewa, and Mohamed Omar Saad. "Preemptive Dose Adjustment Effect on the Quality of Anticoagulation Management in Warfarin Patients With Drug Interactions: A Retrospective Cohort Study." Clinical and Applied Thrombosis/Hemostasis 25 (January 1, 2019): 107602961987255. http://dx.doi.org/10.1177/1076029619872554.

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One strategy to manage patients on warfarin starting an interacting drug is to increase the frequency of monitoring. Another strategy is to adjust warfarin dose around the time patient is started on an interacting medication, which is known as “preemptive warfarin dose adjustment.” The main objective of this study is to compare preemptive to nonpreemptive strategy and their impact on the quality of anticoagulation management. This is a retrospective cohort study performed at the pharmacist-managed anticoagulation clinic in a tertiary hospital in the State of Qatar. Over a 4-year period, 340 pa

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Snyder, Megan Lian, Eirwen Murray Miller, Liliana Cruz, Jessica DeLeeuw, Emily Snell, and Nujsaubnusi Cassandra Vue. "Preoperative Diagnostic Evaluation in Patients Undergoing Hysterectomy and the Incidence of Incidental Diagnosis of Gynecologic Malignancy: A Single-Institution Experience in a Tertiary Care Setting [ID 1663]." Obstetrics & Gynecology 145, no. 6S (2025): 10S. https://doi.org/10.1097/aog.0000000000005916.033.

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INTRODUCTION: The incidence of endometrial cancer diagnosis after a benign hysterectomy is reported to be very rare. Delayed cancer diagnosis may result in additional surgery, delayed adjuvant therapy, and poorer patient outcomes. The objective of this study is to assess the incidence of incidental diagnosis of endometrial cancer and trends in preoperative evaluation of hysterectomies in a high-volume tertiary care setting. METHODS: Patients aged 18–100 who underwent a hysterectomy for benign indication between January 1, 2022, and December 31, 2022, were included. Exclusion criteria were hyst

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Beers, Lisa, Lisa P. van Adrichem, Jelle C. L. Himmelreich, et al. "Manual QT interval measurement with a smartphone-operated single-lead ECG versus 12-lead ECG: a within-patient diagnostic validation study in primary care." BMJ Open 11, no. 11 (2021): e055072. http://dx.doi.org/10.1136/bmjopen-2021-055072.

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ObjectiveTo determine the accuracy of QT measurement in a smartphone-operated, single-lead ECG (1L-ECG) device (AliveCor KardiaMobile 1L).DesignCross-sectional, within-patient diagnostic validation study.Setting/participantsPatients underwent a 12-lead ECG (12L-ECG) for any non-acute indication in primary care, April 2017–July 2018.InterventionSimultaneous recording of 1L-ECGs and 12L-ECGs with blinded manual QT assessment.Outcomes of interest(1) Difference in QT interval in milliseconds (ms) between the devices; (2) measurement agreement between the devices (excellent agreement <20 ms and

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Velasquez, A. E., J. Manríquez, D. Veraguas, F. O. Castro, and L. I. Rodríguez-Alvarez. "105 BOVINE DEMI-BLASTOCYSTS ARE ABLE TO EXPAND TO A SIZE SIMILAR TO INTACT BLASTOCYSTS UNTIL AT LEAST DAY 13 OF IN VITRO CULTURE." Reproduction, Fertility and Development 28, no. 2 (2016): 182. http://dx.doi.org/10.1071/rdv28n2ab105.

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Embryo bisection has been used to produce identical twins, to increase the pregnancy rate per embryo, and for preimplantation diagnosis. However, the invasive nature of splitting might affect development decreasing embryo survival. In general, after bisection or biopsy, embryos are transferred to surrogate mothers and their competence evaluated in terms of implantation and pregnancy maintenance. However, this makes it difficult to evaluate the immediate response of each embryo to bisection. Our aim was to evaluate embryo growth during the 5 days following bisection by using an extended in vitr

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Chubarova, N. Y., A. A. Poliukhov, and I. D. Gorlova. "Long-term variability of aerosol optical thickness in Eastern Europe over 2001–2014 according to the measurements at the Moscow MSU MO AERONET site with additional cloud and NO<sub>2</sub> correction." Atmospheric Measurement Techniques Discussions 8, no. 7 (2015): 7843–78. http://dx.doi.org/10.5194/amtd-8-7843-2015.

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Abstract. The aerosol properties of the atmosphere were obtained within the framework of the AERONET program at the Moscow State University Meteorological Observatory (Moscow MSU MO) over 2001–2014 period. The quality data control has revealed the necessity of their additional cloud and NO2 correction. The application of cloud correction according to hourly visual cloud observations provides a decrease in average aerosol optical thickness (AOT) at 500 nm of up to 0.03 compared with the standard dataset. We also show that the additional NO2 correction of the AERONET data is needed in large mega

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Eberlein, Charlotte V. "Germination ofSorghum almumSeeds and Longevity in Soil." Weed Science 35, no. 6 (1987): 796–801. http://dx.doi.org/10.1017/s0043174500079364.

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Sorghum-almum (Sorghum almumParod. # SORAL) is a weakly perennial, rhizomatous grass that in northern climates reproduces mainly by seeds. Environmental factors influencing seed germination and the longevity of buried seeds were studied in growth chamber and field experiments. Alternating temperatures of 20 C for 16 h and 30 C for 8 h were optimum for germination. Light was not critical to germination. Germination varied only slightly across a pH range from 5.0 to 8.8 but decreased sharply below pH 5. Osmotic potentials greater than −0.9 MPa reduced germination substantially, and no germinatio

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Allez, M., B. Verstockt, C. M. Crosby, et al. "P0828 The impact of etrasimod on neutrophils in the ELEVATE UC clinical programme." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i1579—i1580. https://doi.org/10.1093/ecco-jcc/jjae190.1002.

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Abstract Background Neutrophils are thought to play a role in the pathogenesis of ulcerative colitis (UC); they are believed to be the principal source of faecal calprotectin and are a histological marker of disease activity in mucosal biopsies. Etrasimod is an oral, once-daily, selective sphingosine 1-phosphate (S1P)1,4,5 receptor modulator for the treatment of moderately to severely active UC. This post hoc analysis evaluated neutrophils in patients (pts) receiving etrasimod or placebo (PBO) in the ELEVATE UC clinical programme. Methods We assessed percentage changes from baseline (BL) in ab

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Babiker, Amir, Bothainah Al Aqeel, Sarah Marie, et al. "Quality of Life and Glycemic Control in Saudi Children with Type 1 Diabetes at Different Developmental Age Groups." Clinical Medicine Insights: Endocrinology and Diabetes 14 (January 2021): 117955142199067. http://dx.doi.org/10.1177/1179551421990678.

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Background: Children with type 1 diabetes (T1D) at different stages of development have age-specific needs, which can influence their perception of quality of life (QoL). In our study, we aimed to emphasize these age-specific needs and assess the perception of QoL in Saudi children with T1D, as well as their parents correlating QoL scores with children’s glycemic control. Methods: This is a cross-sectional study in which children with T1D and their parents from 2 tertiary institutes in Saudi Arabia have answered a standard diabetes-specific QoL questionnaire (PedsQL™ 3.0 diabetes module, trans

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Tavares, Antonio Clarette Santiago, Sergio Nascimento Duarte, Nildo Da Silva Dias, Francisco Vanies Da Silva Sá, Jarbas Honório de Miranda, and Cleyton Dos Santos Fernandes. "PRODUÇÃO E MATURAÇÃO DE CANA-DE-AÇÚCAR SUBMETIDA A ENCHARCAMENTO EM DIFERENTES ESTÁDIOS DE DESENVOLVIMENTO." IRRIGA 22, no. 1 (2018): 154–66. http://dx.doi.org/10.15809/irriga.2017v22n1p154-166.

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PRODUÇÃO E MATURAÇÃO DE CANA-DE-AÇÚCAR SUBMETIDA A ENCHARCAMENTO EM DIFERENTES ESTÁDIOS DE DESENVOLVIMENTO ANTONIO CLARETTE SANTIAGO TAVARES1; SERGIO NASCIMENTO DUARTE2; NILDO DA SILVA DIAS3; FRANCISCO VANIES DA SILVA SÁ4; JARBAS HONÓRIO DE MIRANDA2 E CLEYTON DOS SANTOS FERNANDES5 Agrônomo, Prof. Doutor, Instituto Federal do Norte de Minas Gerais, IFNMG, Campus Almenara. antonioirrigacao@yahoo.com.br.2Engenheiro Agrônomo, Prof. Associado 2, Escola Superior de Agricultura “Luiz de Queiroz”, ESALQ/USP. snduarte@usp.br, jhmirand@usp.br3Agrônomo, Prof. Doutor, Universidade Federal Rural do Semi-Ár

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Chubarova, N. Y., A. A. Poliukhov, and I. D. Gorlova. "Long-term variability of aerosol optical thickness in Eastern Europe over 2001–2014 according to the measurements at the Moscow MSU MO AERONET site with additional cloud and NO<sub>2</sub> correction." Atmospheric Measurement Techniques 9, no. 2 (2016): 313–34. http://dx.doi.org/10.5194/amt-9-313-2016.

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Abstract. The atmospheric aerosol properties were obtained within the framework of the AERONET program at the Moscow State University Meteorological Observatory (Moscow MSU MO) over the 2001–2014 period. The quality data control has revealed the necessity of additional cloud screening and NO2 correction. The application of additional cloud screening according to hourly visual cloud observations provides a decrease in monthly average aerosol optical thickness (AOT) at 500 nm of up to 0.03 compared with the standard data set. We also show that the additional NO2 correction of the AERONET version

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Fernandez, Adrian N., Kevin D. Li, Hiren V. Patel, et al. "Injuries With Electric vs Conventional Scooters and Bicycles." JAMA Network Open 7, no. 7 (2024): e2424131. http://dx.doi.org/10.1001/jamanetworkopen.2024.24131.

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ImportanceMicromobility, the use of small vehicles (primarily scooters and bicycles), has become a standard transportation method in the US. Despite broad adoption of electric micromobility vehicles, there is a paucity of data regarding the injury profiles of these vehicles, particularly in the US.ObjectiveTo characterize micromobility injury trends in the US, identify demographic characteristic differences in users of electric and conventional vehicles, and identify factors associated with hospitalization.Design, Setting, and ParticipantsThis cross-sectional study queried the National Electro

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McCann, Kelly Elizabeth, Virginia G. Kaklamani, Noran Osman, et al. "Treatment patterns of goserelin 3.6 mg once monthly and 10.8 mg every three months in women with breast cancer: A real-world analysis." JCO Oncology Practice 20, no. 10_suppl (2024): 391. http://dx.doi.org/10.1200/op.2024.20.10_suppl.391.

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391 Background: Goserelin is a gonadotropin-releasing hormone agonist used for ovarian function suppression in the treatment of pre- and peri-menopausal patients with breast cancer. Goserelin, administered as a subcutaneous implant, is available in doses of 3.6 mg once monthly or 10.8 mg every three months; goserelin 3.6 mg is approved in the US, and both the 3.6 mg and 10.8 mg doses are approved by Health Canada and the European Medicines Agency. A study utilizing US real-world evidence was conducted to characterize treatment patterns of patients treated with goserelin 3.6 mg and/or 10.8 mg.

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Watanabe, Yasuhiro, Takashi Yamaguchi, Shuhei Yamaoka, et al. "Effect of Conventional Medical Therapy or Laparoscopic Sleeve Gastrectomy on Urinary Albumin in Japanese Subjects with Severe Obesity: An Observational Study." Obesity Facts 14, no. 6 (2021): 613–21. http://dx.doi.org/10.1159/000519156.

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<b><i>Introduction:</i></b> In patients with severe obesity, albuminuria can be improved by both conventional medical therapy and bariatric surgery. The purpose of this study was to compare the impact of weight loss achieved through conventional medical therapy or laparoscopic sleeve gastrectomy (LSG) on albuminuria in Japanese subjects with severe obesity and identify the factors involved. <b><i>Methods:</i></b> We retrospectively evaluated the clinical characteristics including the urinary albumin/creatinine ratio (UACR) of 340 consecutive subj

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Huber, Sandra, Stephan Hutter, Constance Regina Baer, et al. "Similarities and Differences of DNMT3A, TET2 and ASXL1 Mutations across Ccus, MDS and AML." Blood 144, Supplement 1 (2024): 1819. https://doi.org/10.1182/blood-2024-200561.

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Background: The most frequently mutated genes in clonal hematopoiesis (CH) occurring during aging are DNMT3A, TET2, and ASXL1 (DTA). DTA mutations (mut) also recurrently occur in overt myeloid malignancies. Aim: Analyze similarities and differences regarding incidence, co-aberrations and clonal hierarchy across CCUS, MDS and AML in patients with DTAmut. Methods: We analyzed 1,604 samples (received 2005-2021) of patients (median age: 71 years [2-93]; female: 42%) diagnosed with CCUS (n=222) or a non-therapy related myeloid malignancy (MDS: n=637; AML: n=745). All samples were analyzed by WGS (m

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Borad, Mitesh J., Shantan G. Reddy, Nathan Bahary, et al. "Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer." Journal of Clinical Oncology 33, no. 13 (2015): 1475–81. http://dx.doi.org/10.1200/jco.2014.55.7504.

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Purpose TH-302 is an investigational hypoxia-activated prodrug that releases the DNA alkylator bromo-isophosphoramide mustard in hypoxic settings. This phase II study (NCT01144455) evaluated gemcitabine plus TH-302 in patients with previously untreated, locally advanced or metastatic pancreatic cancer. Patients and Methods Patients were randomly assigned 1:1:1 to gemcitabine (1,000 mg/m2), gemcitabine plus TH-302 240 mg/m2 (G+T240), or gemcitabine plus TH-302 340 mg/m2 (G+T340). Randomized crossover after progression on gemcitabine was allowed. The primary end point was progression-free surviv

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Benatar, Michael, Heinz Wiendl, Richard Nowak, Yan Zheng, and William Macias. "Batoclimab as induction and maintenance therapy in patients with myasthenia gravis: rationale and study design of a phase 3 clinical trial." BMJ Neurology Open 6, no. 1 (2024): e000536. http://dx.doi.org/10.1136/bmjno-2023-000536.

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IntroductionBatoclimab, a fully human monoclonal antibody that inhibits the neonatal fragment crystallisable receptor, has shown promising phase 2 clinical trial results in patients with generalised myasthenia gravis (gMG).Methods and analysisIn this phase 3, randomised, quadruple-blind, placebo-controlled study, adults with gMG will be randomised 1:1:1 to induction therapy with batoclimab 680 mg, batoclimab 340 mg, or placebo, administered once weekly (QW) for 12 weeks as a subcutaneous injection. The primary endpoint is the change from baseline to week 12 on the Myasthenia Gravis Activities

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Moroni, L., M. Mazzetti, G. A. Ramirez, et al. "POS0726 POST-TRAUMATIC STRESS DISORDER AND QUALITY OF LIFE IN SYSTEMIC LUPUS ERYTHEMATOSUS. A CROSS SECTIONAL WEB SURVEY-BASED STUDY." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 613.1–613. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1238.

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Background:Exposure to severe or chronic life stressors may alter immune function and high levels of subsequent distress have been implicated in autoimmune disease pathogenesis. Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition affecting 1-12% of the general population1, occurring in response to traumatic events. Growing evidence supports an association between trauma exposure and PTSD with systemic lupus erythematosus (SLE) onset2.Objectives:To cross-sectionally assess PTSD prevalence in a cohort of patients with SLE and to examine its correlation with quality of l

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Kadia, Tapan, Jorge E. Cortes, Elias J. Jabbour, et al. "Phase II Study of Cladribine, Idarubicin, and Cytarabine (araC) in Patients with Acute Myeloid Leukemia (AML)." Blood 126, no. 23 (2015): 2541. http://dx.doi.org/10.1182/blood.v126.23.2541.2541.

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Abstract Background Slow progress has been made in improving induction therapy for patients (pts) with AML. Nucleoside analogues such as cladribine can increase the efficacy of araC by modulating deoxycytidine kinase. Indeed, the addition of cladribine to standard 7+3 chemotherapy has been shown to improve survival in pts with AML (Holowiecki JCO 2012). Additionally, higher doses of araC during induction may have a role in improving outcomes for younger pts (Burnett JCO 2013, Willemze JCO 2013). We conducted a trial to study the efficacy of cladribine combined with higher-dose araC during indu

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Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a

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Peng, Xingchen, Xuan He, Weiwei Zhang, et al. "Safety, tolerability, and immunogenicity of WGc-043 in subjects with EBV-positive cancers: Results from an investigator-initiated trial." Journal of Clinical Oncology 42, no. 23_suppl (2024): 139. http://dx.doi.org/10.1200/jco.2024.42.23_suppl.139.

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139 Background: The Epstein-Barr virus (EBV) persists and spreads after infection in humans, leading to the occurrence and metastasis of a variety of cancers, posing great challenges in the treatment of cancer.. Conventional cancer therapies tend to have limited success and significant side effects. Therefore, there is an urgent need to develop more safe and efficient treatments such as innovative mRNA vaccines, which provide a new approach to cancer immunotherapy. WGc-043, an mRNA vaccine targeting EBV-positive tumor associated antigens, was evaluated for safety, tolerability, and immunogenic

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Ferreira, Raquel Teixeira, Marcela Araújo Soares Coutinho, David do Carmo Malvar, et al. "Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid fromKalanchoe pinnata." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/429256.

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Kalanchoe pinnata(KP) is popularly used for treating inflammatory diseases. This study investigated the antinociceptive, antiedematogenic, and anti-inflammatory potential of the subcutaneous administration of KP flower aqueous extract (KPFE), its ethyl acetate (EtOAcF) and butanol (BuOHF) fractions, and the main KP flavonoid [quercetin 3-O-α-L-arabinopyranosyl (1→2)α-L-rhamnopyranoside] (KPFV) in mice, as well as its possible mechanisms of action. KPFE (30–300 mg/kg) and KPFV (1–10 mg/kg) inhibited the acetic acid-induced writhing (ID50= 164.8 and 9.4 mg/kg, resp.). KPFE (300 mg/kg), EtOAcF (1

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Matić, Sanja, Snežana Stanić, Desanka Bogojević, et al. "Extract of the plant Cotinus coggygria Scop. attenuates pyrogallol-induced hepatic oxidative stress in Wistar rats." Canadian Journal of Physiology and Pharmacology 89, no. 6 (2011): 401–11. http://dx.doi.org/10.1139/y11-043.

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To examine the protective potential of the Cotinus coggygria Scop. methanol extract, Wistar rats were treated with the hepatotoxic compound pyrogallol, which possesses a potent ability to generate free radicals and induce oxidative stress. The ability of the extract to counteract the oxidative stress was examined in rats that were injected with the extract intraperitoneally (500 mg·(kg body weight)–1) either 2 or 12 h before the pyrogallol treatment. The extract possesses a reducing activity in vitro and an ability to chelate the ferrous ion both in vivo and in vitro. Application of the extrac

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Wondafrash, Mekitie, Lieven Huybregts, Carl Lachat, Kimberley P. Bouckaert, and Patrick Kolsteren. "Dietary diversity predicts dietary quality regardless of season in 6–12-month-old infants in south-west Ethiopia." Public Health Nutrition 19, no. 14 (2016): 2485–94. http://dx.doi.org/10.1017/s1368980016000525.

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AbstractObjectiveSimple, cost-effective and convenient instruments like food group-based scores are proposed to assess micronutrient adequacy of children in developing countries. We assessed the predictive ability and seasonal stability of a dietary diversity score (DDS) to indicate dietary quality of infants.DesignA 24 h dietary recall assessment was carried out on a sample of 320 and 312 breast-fed infants aged 6–12 months during harvest (HS) and pre-harvest (PHS) seasons, respectively, in Ethiopia. DDS was calculated based on seven food groups, while mean micronutrient density adequacy (MMD

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Schutte, Maria C., Leslie Hebb, Simon Lowry, et al. "Modeling Stellar Surface Features on a Subgiant Star with an M-dwarf Companion." Astronomical Journal 164, no. 1 (2022): 14. http://dx.doi.org/10.3847/1538-3881/ac70ca.

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Abstract Understanding magnetic activity on the surface of stars other than the Sun is important for exoplanet analyses to properly characterize an exoplanet’s atmosphere and to further characterize stellar activity on a wide range of stars. Modeling stellar surface features of a variety of spectral types and rotation rates is key to understanding the magnetic activity of these stars. Using data from Kepler, we use the starspot modeling program STarSPot (STSP) to measure the position and size of spots for KOI-340, which is an eclipsing binary consisting of a subgiant star (T eff = 5593 ± 27 K,

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de Paula, AB, SBP de Fúcio, RCB Alonso, GMB Ambrosano, and RM Puppin-Rontani. "Influence of Chemical Degradation on the Surface Properties of Nano Restorative Materials." Operative Dentistry 39, no. 3 (2014): E109—E117. http://dx.doi.org/10.2341/12-340.

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SUMMARY Objectives The aim of this in vitro study was to investigate the effect of chemical degradation on the surface roughness (Ra) and hardness (Knoop hardness number [KHN]) of nano restorative materials. Methods Disc-shaped specimens (5-mm diameter; 2-mm thick) of Filtek Z350 and TPH Spectrum composites and the Vitremer and Ketac Nano light-curing glass ionomer cements were prepared according to the manufacturers' instructions. After 24 hours, polishing procedures were performed and initial measurements of Ra and KHN were taken. The specimens were divided into 12 groups (n=10) according to

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Niewald, Marcus, Lara Natalie Müller, Matthias G. Hautmann, et al. "ArthroRad trial: multicentric prospective and randomized single-blinded trial on the effect of low-dose radiotherapy for painful osteoarthritis depending on the dose—results after 3 months’ follow-up." Strahlentherapie und Onkologie 198, no. 4 (2021): 370–77. http://dx.doi.org/10.1007/s00066-021-01866-2.

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Abstract Purpose Randomized comparison of the effect of radiotherapy on painful osteoarthritis (OA) applying a standard-dose vs. a very-low-dose regime Patients and methods Patients with OA of the hand and knee joints were included. Further inclusion criteria: symptoms for more than 3 months, favorable general health status, age above 40 years. Patients with prior local radiotherapy, trauma, rheumatoid arthritis, or vascular diseases were excluded. After randomization (every joint was randomized separately), the following protocols were applied: standard arm: total dose 3.0 Gy, single fraction

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Rashid, Taslima, Nirmitha Jayaratne, Marjan Taher, Tristan Barber, Nneka Nwokolo, and Michael Rayment. "P028 Characterising neisseria gonorrhoeae (NG) infections and treatment in a large, urban cohort." Sexually Transmitted Infections 93, Suppl 1 (2017): A26.3—A27. http://dx.doi.org/10.1136/sextrans-2017-053232.74.

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IntroductionBetter detection and more frequent testing may explain increases in NG. We wished to characterise patients attending our clinics with NG, and audit management against BASHH standards.Methods300 sequential NG patients attending in 2016 were reviewed. Data collected: demographics, NAAT/culture positivity (per site), antimicrobial treatment and resistance, and test of cure (TOC).ResultsMean age was 34 (17–65); 92% male; 75% white; 86% MSM. 415 site specific infections captured. Site distribution by NAAT, culture concordance/sensitivities, and TOC are presented below:Abstract P028 Tabl

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Kim, Sung Guen. "Smooth symmetric bilinear forms on ${\mathcal L}_s(^2l_{\infty}^2)$." Carpathian Mathematical Publications 14, no. 1 (2022): 20–28. http://dx.doi.org/10.15330/cmp.14.1.20-28.

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In [Carpathian Math. Publ. 2020, 12 (2), 340-352], the author classified the extreme points and exposed points of the unit ball of the space of symmetric bilinear forms on the space ${\mathcal L}_s(^2l_{\infty}^2)$, where ${\mathcal L}_s(^2l_{\infty}^2)$ is the space of symmetric bilinear forms on the plane with the supremum norm. Motivated by this paper, we classify the smooth points of the unit ball of the space of symmetric bilinear forms on ${\mathcal L}_s(^2l_{\infty}^2).$

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Kim, Sung Guen. "Smooth symmetric bilinear forms on ${\mathcal L}_s(^2l_{\infty}^2)$." Carpathian Mathematical Publications 14, no. 1 (2022): 20–28. http://dx.doi.org/10.15330/cmp.14.1.20-28.

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In [Carpathian Math. Publ. 2020, 12 (2), 340-352], the author classified the extreme points and exposed points of the unit ball of the space of symmetric bilinear forms on the space ${\mathcal L}_s(^2l_{\infty}^2)$, where ${\mathcal L}_s(^2l_{\infty}^2)$ is the space of symmetric bilinear forms on the plane with the supremum norm. Motivated by this paper, we classify the smooth points of the unit ball of the space of symmetric bilinear forms on ${\mathcal L}_s(^2l_{\infty}^2).$

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พรมพิพักต์, พงษ์พันธ์, วรวุฒิ สุวรรณเรือง та พิเชฐ มีสัจจ์. "การศึกษาการผลิตไฟฟ้าพลังงานน้ำจากปลายท่อส่งน้ำของการประปาก่อนไหลลงถังเก็บน้ำใต้ดิน". Frontiers in Engineering Innovation Research 22, № 1 (2024): 9–16. http://dx.doi.org/10.60101/feir.2024.253458.

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งานวิจัยนี้มุ่งเน้นที่จะศึกษาการผลิตพลังงานไฟฟ้าจากพลังงานเหลือทิ้งของการไหลของน้ำที่ปลายท่อ ก่อนไหลลงสู่ถังเก็บน้ำใต้ดิน จากการวัดความดันที่ปลายท่อส่งน้ำขนาดเส้นผ่านศูนย์กลาง 2 นิ้ว มีค่าเฉลี่ยที่ 1.0 bar ซึ่งชุดผลิตไฟฟ้าจะประกอบไปด้วย 2 ส่วนหลัก คือ ส่วนแรกเป็นกังหันน้ำแบบเพลตัน (Pelton Turbine) มีหน้าที่เปลี่ยนพลังงานน้ำให้เป็นพลังงานกล ออกแบบให้ขนาดรัศมีของใบพัดเท่ากับ 150 mm และจำนวนของแผ่นรับน้ำ (Bracket) รูปทรงครึ่งวงกลมที่มีเส้นผ่านศูนย์กลาง 65 mm จำนวน 12 แผ่น และส่วนที่ 2 ได้นำเอามอเตอร์ไฟฟ้าซิงโครนัสชนิดแม่เหล็กถาวร (PMSM) ขนาด 340 W มาเปลี่ยนหน้าที่ให้เป็นเครื่องกำเนิดไฟฟ้าโดยตรง เ

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Clauss, Delphine, Vincent Martin, Jakub Drnec, Marta Mirolo, Laetitia Dubau, and Frederic Maillard. "Deciphering the Roles of Chemistry and Structure in Iridium Oxide Oxygen Evolution Catalysts through the Study of Annealed Iridium Oxide Nanoparticles." ECS Meeting Abstracts MA2023-02, no. 42 (2023): 2080. http://dx.doi.org/10.1149/ma2023-02422080mtgabs.

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The development of proton exchange membrane (PEM) water electrolysis, which enables the production of de-carbonized hydrogen, is hindered by the low efficiency of the oxygen evolution reaction (OER). This is especially true in acidic environment where only noble metals (mainly Ru and Ir) can be used as electrocatalysts. Iridium oxide nanocatalysts (IrOx) are promising due to their high OER activity and good resistance to acidic and oxidative conditions. However, finding a compromise between their electrocatalytic activity and stability remains challenging. Moreover, it is not yet clear which p

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Karpenya, М. М. "ETHOLOGICAL FEATURES AND HEMATOLOGICAL INDICATORS OF REPLACING HEIFERS WHEN GROWING AT DIFFERENT FLOOR SPACES." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 57, no. 2 (2021): 118–22. http://dx.doi.org/10.52368/2078-0109-2021-57-2-118-122.

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As a result of the studies it was found that rearing of replacing heifers on the floor space of 1.6 m2 per head between 1 and 6 months of age, 2.5 m2 – from 6 to 12 months, and 3.0 m2 – from 12 to 18 months helps in prolonging the period of cud chewing in a standing position by 1.9 – 2.4 times, and the chewing period of food by 2.1-2.2 times. It also positively affects some blood indicators, which was expressed in a reliable increase in the lysozyme activity of blood serum by 0.2–0.3 p.p., phagocytic activity of neutrophils – by 2.7–3.0 p.p., hemoglobin content by – 3.9–4.5% and total protein

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Debad, Jeff D., та Ross H. Hill. "The photochemistry of cylopentadienylmolybdenum complexes including the mechanism of the cis-trans photoisomerism of (η5-C5H5)Mo(CO)2LX, X = Cl Br, I; L = PPh3, PBu3". Canadian Journal of Chemistry 68, № 12 (1990): 2216–20. http://dx.doi.org/10.1139/v90-340.

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Photolysis of trans-(η5-C5H5)Mo(CO)2LX (L = PPh3, PBu3; X = Br, I), at 12 K in 1,2-epoxyethylbenzene, results in CO loss. The product is formed as a specific isomer of (η5-C5H5)Mo(CO)LX, isomer 1. This isomer, upon warming, yields only trans-(η5-C5H5)Mo(CO)2LX in its reaction with CO. Photolysis of cis-(η5-C5H5)Mo(CO)2LX (L = PPh3, PBu3; X = Cl, Br, I) under similar conditions also results in CO loss to generate the unsaturated intermediate, (η5-C5H5)Mo(CO)LX as a different geometric isomer, isomer 2. The unsaturated intermediate, isomer 2, reacts thermally with CO to generate only cis-(η5-C5H

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Ledu, David, André Rochon, Anne de Vernal, and Guillaume St-Onge. "Palynological evidence of Holocene climate change in the eastern Arctic: a possible shift in the Arctic oscillation at the millennial time scaleThis article is one of a series of papers published in this Special Issue on the theme Polar Climate Stability Network." Canadian Journal of Earth Sciences 45, no. 11 (2008): 1363–75. http://dx.doi.org/10.1139/e08-043.

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Dinocyst assemblages and the physical properties of two sediment cores collected in the easternmost part of the main axis of the Northwest Passage, Canadian Arctic Ocean (cores 2004-804-009 BC and 2004-804-009 PC, 74°11.2′N, 81°11.7′W) were used to reconstruct changes in sea-surface conditions and to characterize changes in the depositional environment. Core 2004-804-009 PC spans the last 12 180 calibrated (cal) years BP, with sedimentation rates ranging from 45 to 122 cm/ka. Quantitative estimates of sea-surface parameters reveal relatively large hydrographic variability at millennial time sc

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Bilen, Mehmet Asim, Yuan Liu, Bassel Nazha, et al. "Phase 2 study of neoadjuvant cabozantinib in patients with locally advanced non-metastatic clear cell renal cell carcinoma." Journal of Clinical Oncology 40, no. 6_suppl (2022): 340. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.340.

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340 Background: Cabozantinib is a small molecule inhibitor of the tyrosine kinases c-Met, AXL and VEGFR2 that has been shown to reduce tumor growth, metastasis, and angiogenesis. After the promising results from the METEOR, CABOSUN and Checkmate-9ER trials, cabozantinib was approved for use in patients with advanced renal cell carcinoma (RCC). The increased response rates with cabozantinib in metastatic RCC, along with the other neoadjuvant TKI data, support an expanded role for cabozantinib in the neoadjuvant setting. Methods: Patients with clinical stage ≥ T3Nx or TanyN+ or deemed unresectab

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Zivelin, Ariella, Ronit Mor-Cohen, Victoria Kovalsky, et al. "Prothrombin 20210G>A is an ancestral prothrombotic mutation that occurred in whites approximately 24 000 years ago." Blood 107, no. 12 (2006): 4666–68. http://dx.doi.org/10.1182/blood-2005-12-5158.

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Abstract Prothrombin 20210G>A and factor V Leiden are common prothrombotic mutations in whites for which founder effects have been established. In this study, we analyzed the frequencies of 5 single nucleotide polymorphisms (SNPs) and 9 microsatellites flanking the prothrombin gene (F2) in 88 homozygotes for 20210A and 66 homozygotes for 20210G. For estimating the age of the prothrombin 20210G>A mutation, we used the DMLE+2.0 program, which analyzed linkage disequilibria between the mutation and the multiple markers that had been assessed. This analysis yielded an age estimate of 23 720

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