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1

O’Neill, Jennifer R., Karin A. Pfeiffer, Marsha Dowda, and Russell R. Pate. "In-school and Out-of-school Physical Activity in Preschool Children." Journal of Physical Activity and Health 13, no. 6 (2016): 606–10. http://dx.doi.org/10.1123/jpah.2015-0245.

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Background:Little is known about the relationship between children’s physical activity (PA) in preschool (in-school) and outside of preschool (out-of-school). This study described this relationship.Methods:Participants were 341 children (4.6 ± 0.3 years) in 16 preschools. Accelerometers measured moderate-to-vigorous physical activity (MVPA) and total physical activity (TPA) in-school and out-of-school. In the full sample, Pearson correlation was used to describe associations between in-school and out-of-school PA. In addition, children were categorized as meeting or not meeting a PA guideline
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Dowling, Brittany, Derrick M. Knapik, Micheal J. Luera, Grant E. Garrigues, Gregory P. Nicholson, and Nikhil N. Verma. "Influence of Pelvic Rotation on Lower Extremity Kinematics, Elbow Varus Torque, and Ball Velocity in Professional Baseball Pitchers." Orthopaedic Journal of Sports Medicine 10, no. 11 (2022): 232596712211303. http://dx.doi.org/10.1177/23259671221130340.

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Background: Early pelvic rotation has been associated with decreased throwing arm kinetics in college baseball pitchers, though professional pitchers have yet to be examined. Purpose: To investigate the effect of pelvic rotation on trunk, pelvis and lower extremity kinematics, as well as throwing arm kinetics and pitch velocity in professional baseball pitchers. Study Design: Descriptive laboratory study. Methods: Data were analyzed for 157 professional baseball pitchers throwing fastballs using 3-dimensional motion capture (480 Hz). Pitchers were divided into an open pelvis (rotated toward ta
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Al-Awadhi, Aydah, Mohammed Hourani, Mawada Hussein, et al. "Abstract P1-14-01: Incidence, Clinicopathological Features and Treatment Outcomes Of Young Breast Cancer Patients: A Cohort Analysis From a High-Volume Tertiary Cancer Center in The United Arab Emirates." Cancer Research 83, no. 5_Supplement (2023): P1–14–01—P1–14–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-p1-14-01.

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Abstract Introduction: Breast cancer (BC) in women age 40 or younger represents approximately 7% of all BC cases. Studies have reported that BC in younger women is more likely to have adverse tumor characteristics and outcomes when compared to elder women. Despite the fact that BC in the Middle East seems to occur at a younger age, data on tumor characteristics in these patients are scarce, especially in the United Arab Emirates. Objective: This study was conducted to investigate the incidence, clinicopathological characteristics, treatment modalities, and outcomes of young BC patients at a ma
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Karrar, Omer, Moazah Iftikhar, Kristen McCullough, et al. "Survival and Prognosis Among 301 Patients with Newly-Diagnosed Acute Myeloid Leukemia Following Venetoclax Plus Hypomethylating Agent Therapy." Blood 142, Supplement 1 (2023): 591. http://dx.doi.org/10.1182/blood-2023-178837.

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Background: Venetoclax (Ven) in combination with hypomethylating agent (HMA) is the preferred treatment for elderly/unfit patients with newly-diagnosed acute myeloid leukemia (AML). Current prognostication for AML is based on European LeukemiaNet (ELN) genetic risk stratification which has limited applicability in patients treated with Ven-HMA ( Blood, 2022). Accordingly, our primary objective was to determine predictors of treatment response and survival outcomes in treatment-naïve AML patients receiving Ven-HMA. Methods: Our study population was recruited from Mayo Clinic (MN, FL, AZ), after
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Warner, M., P. Tollet, M. Strömstedt, K. Carlström, and J. Å. Gustafsson. "Endocrine regulation of cytochrome P-450 in the rat brain and pituitary gland." Journal of Endocrinology 122, no. 1 (1989): 341–49. http://dx.doi.org/10.1677/joe.0.1220341.

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ABSTRACT In an effort to understand the physiological functions of cytochrome P-450 in the central nervous system and pituitary gland, we evaluated changes in the level of the enzyme as a function of the endocrine status of rats and the ability of these tissues to synthesize or degrade steroids. The P-450 content of microsomes prepared from the hypothalamic preoptic area (HPOA), the olfactory lobes and the cerebrum was 0·040 ± 0·009 and in the pituitary gland 2·2 ± 0·6 (s.d.) nmol/g tissue. The P-450 content of the HPOA and olfactory lobes, but not of the rest of the cerebrum, was influenced b
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Lykova, Inna, Ralph Rowe, Glenn Poirier, Henrik Friis, and Kate Helwig. "Mckelveyite group minerals – Part 4: Alicewilsonite-(YLa), Na2Sr2YLa(CO3)6 ⋅ 3H2O, a new lanthanum-dominant species from the Paratoo mine, Australia." European Journal of Mineralogy 36, no. 2 (2024): 301–10. http://dx.doi.org/10.5194/ejm-36-301-2024.

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Abstract. The new mckelveyite group mineral, alicewilsonite-(YLa), Na2Sr2YLa(CO3)6 ⋅ 3H2O, was found together with kamphaugite-(Y), paratooite-(Y), bastnäsite-(La), and decrespignyite-(Y) coating along fractures in dolomite at the Paratoo copper mine, South Australia, Australia. It occurs as pale pink to colourless pseudohexagonal tabular crystals up to 150 µm in size. The streak is white; the lustre is vitreous. The mineral has no cleavage. Dcalc is 3.37 g cm−3. Alicewilsonite-(YLa) is optically biaxial (−), α = 1.556(2), β= 1.582(2), γ= 1.592(2), 2V (meas.) = 60(2)°, 2V (calc.) = 63° (589 nm
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Lykova, Inna, Ralph Rowe, Glenn Poirier, Henrik Friis, and Kate Helwig. "Mckelveyite group minerals – Part 2: Alicewilsonite-(YCe), Na2Sr2YCe(CO3)6 ⋅ 3H2O, a new species." European Journal of Mineralogy 35, no. 1 (2023): 143–55. http://dx.doi.org/10.5194/ejm-35-143-2023.

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Abstract. The new mckelveyite group mineral alicewilsonite-(YCe), ideally Na2Sr2YCe(CO3)6 ⋅ 3H2O, was found at Mont Saint-Hilaire, Quebec, Canada, and subsequently at the Saint-Amable sill, Quebec, Canada, and the Khibiny Massif, Kola Peninsula, Russia. Alicewilsonite-(YCe) crystals are commonly hemimorphic pseudotrigonal and pseudohexagonal and show barrel-shaped, saucer-shaped, spindle-shaped, cone-shaped, columnar, tabular, and platy habits. They are usually up to 2–3 mm in size with some larger crystals reaching 2–3 cm. The crystals often form stacked or parallel growth aggregates and rose
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Mehic, Dino, Jasmin Sabrina Rast, Michelle Fuchs, et al. "Utility of the Platelet Function Analyzer (PFA-100) in Patients with Bleeding Disorder of Unknown Cause." Blood 142, Supplement 1 (2023): 3965. http://dx.doi.org/10.1182/blood-2023-185756.

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Introduction: Bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion and patients share a similar phenotype with established mild bleeding disorders (MBDs) such as platelet function defects (PFD), mild von Willebrand disease (VWD), or mild coagulation factor deficiencies (CFD). The integration of global assays, such as the Platelet Function Analyzer (PFA)-100, as screening tools for MBDs lacks universal endorsement and is currently not recommended in clinical routine. While the PFA-100 has demonstrated noteworthy sensitivity in the detection of VWD, data regarding its clinical u
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Green, Michael S., Benjamin T. Corona, J. Andrew Doyle, and Christopher P. Ingalls. "Carbohydrate-Protein Drinks Do Not Enhance Recovery from Exercise-Induced Muscle Injury." International Journal of Sport Nutrition and Exercise Metabolism 18, no. 1 (2008): 1–18. http://dx.doi.org/10.1123/ijsnem.18.1.1.

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This study examined the effects of carbohydrate (CHO), carbohydrate-protein (CHO+PRO), or placebo (PLA) beverages on recovery from novel eccentric exercise. Female participants performed 30 min of downhill treadmill running (–12% grade, 8.0 mph), followed by consumption of a CHO, CHO+PRO, or PLA beverage immediately, 30, and 60 min after exercise. CHO and CHO+PRO groups (n = 6 per group) consumed 1.2 g · kg body weight–1 · hr–1 CHO, with the CHO+PRO group consuming an additional 0.3 g · kg body weight–1 · hr–1 PRO. The PLA group (n = 6) received an isovolumetric noncaloric beverage. Maximal is
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Piccand, Eva, Peter Vollenweider, Idris Guessous, and Pedro Marques-Vidal. "Association between dietary intake and inflammatory markers: results from the CoLaus study." Public Health Nutrition 22, no. 3 (2018): 498–505. http://dx.doi.org/10.1017/s1368980018002355.

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AbstractObjectiveTo assess the associations between single foods, nutrients, dietary patterns and dietary scores, and inflammatory markers (C-reactive protein (CRP), IL-6, TNF-α and leucocyte count).DesignCross-sectional, population-based study.SettingCity of Lausanne, Switzerland, years 2009–2012.SubjectsAdults (n 4027; 46·5 % men), mean age 57·2 (sd 10·2) years. Dietary intake was collected using a semi-quantitative FFQ. Single foods and nutrients, three dietary patterns (‘Meat & fries’; ‘Fruits & vegetables’; ‘Fatty & sugary’) and three dietary scores (two Mediterranean; Alterna
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Grauvogel, Juergen, Jan Kaminsky, and Steffen K. Rosahl. "The Impact of Tinnitus and Vertigo on Patient-Perceived Quality of Life After Cerebellopontine Angle Surgery." Neurosurgery 67, no. 3 (2010): 601–10. http://dx.doi.org/10.1227/01.neu.0000374725.19259.ea.

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Abstract BACKGROUND Quality of life (QOL) has come into focus after treatment for cerebellopontine angle (CPA) lesions. OBJECTIVE This study compared subjective (tinnitus, vertigo) and objective (hearing loss, facial palsy) results of CPA surgery with patient-perceived impairment of QOL. METHODS A retrospective analysis of a consecutive series of 48 patients operated on for either a vestibular schwannoma or a meningioma in the CPA was performed. Patient's subjective impairment of QOL by tinnitus, vertigo, hearing loss, and facial nerve palsy was assessed by a visual analog scale (VAS). Objecti
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Qoniatul Farikhah and Ahmad Mufidz Marzuqi. "Pengaruh Citra Lembaga, Kualitas Pelayanan dan Kepuasan terhadap Loyalitas Muzakki Unit Pengelola Zakat Infaq Shadaqah NU Care-Lazisnu Kecamatan Bandar Kabupaten Batang." Academia: Jurnal Ilmu Sosial dan Humaniora 2, no. 1 (2022): 71–79. http://dx.doi.org/10.54622/academia.v2i1.32.

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Penelitian ini bertujuan untuk mengetahui pengaruh citra lembaga, kualitas pelayanan dan kepuasan terhadap loyalitas muzakki. Penelitian ini menggunakan metode analisis deskriptif. Penelitian ini dilakukan di Sekretariat UPZIS NU CARE-LAZISNU Kecamatan Bandar yang beralamat di Gedung MWC NU Bandar Lt. 2 Jl. Raya Bandar Utara No.01 Bandar 51254 Kabupaten Batang, Jawa Tengah. Penelitian ini mengambil 40 Muzakki UPZIS NU CARE-LAZISNU Kecamatan Bandar sebagai sampel secara acak. Hasil penelitian menunjukkan bahwa Variabel citra lembaga berpengaruh postif terhadap loyalitas muzakki, hal tersebut da
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van Rhee, Frits, Vanessa Bolejack, Klaus Hollmig, et al. "High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis." Blood 110, no. 3 (2007): 827–32. http://dx.doi.org/10.1182/blood-2007-01-067728.

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Abstract Serum-free light chain (SFLC) levels are useful for diagnosing nonsecretory myeloma and monitoring response in light-chain–only disease, especially in the presence of renal failure. As part of a tandem autotransplantation trial for newly diagnosed multiple myeloma, SFLC levels were measured at baseline, within 7 days of starting the first cycle, and before both the second induction cycle and the first transplantation. SFLC baseline levels higher than 75 mg/dL (top tertile) identified 33% of 301 patients with higher near-complete response rate (n-CR) to induction therapy (37% vs 20%, P
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Chaiyodsilp, Sant, Pijika Watcharapichat, Thouantosaporn Suwanjutah, et al. "A Comparison of a Healthy Thai Diet and Contemporary Thai Diet on Health Indices in Individuals With Noncommunicable Diseases: A Randomized Controlled Trial." Ramathibodi Medical Journal 48, no. 1 (2025): e270918. https://doi.org/10.33165/rmj.48.01.e270918.

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Background: Studies have suggested that dietary patterns emphasizing low-fat, plant-based foods like vegetarian, Mediterranean, and Dietary Approaches to Stop Hypertension (DASH) diets reduce noncommunicable disease risk. Objectives: To compare the effects of a Healthy Thai Diet (HTD) and a Contemporary Thai Diet (CTD) on body mass index (BMI), blood pressure, cholesterol, and glycemia. The HTD is characterized by low-fat, plant-based Thai food that substitutes animal products with plant-based ingredients while maintaining traditional seasonings (eg, fish sauce, shrimp paste, and coconut milk)
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Vitovskiy, R., O. Bolshak, V. Boukarim, Yu Bakhovska, and V. Popov. "Mitral Valve Plasty During Correction of Combined Mitral-Aortic Valve Diseases." Ukrainian journal of cardiovascular surgery, no. 4 (41) (December 16, 2020): 63–68. http://dx.doi.org/10.30702/ujcvs/20.4112/059063-068/407-08-097.

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The aim. To study reconstructive operations on the mitral valve (MV) combined with aortic valve replacement (AVR) for combined mitral-aortic valve defects (CMAVD).
 Materials and methods. The study included 1690 patients with CMAVD who underwent surgical treatment at the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine for the period from 01/01/2006 to 01/01/2020. Of these, 429 (23.4%) patients underwent MV reconstruction with AVR.
 The following valve-sparing procedures were performed: – application of annuloplasty ring: 123
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Brunstein, Claudio G., Navneet Majhail, Daniela C. Setubal, et al. "The Predictive Value of the Hematopoietic Cell Transplantation (HCT)-Specific Comorbidity Index (CI) in Recipients of Umbilical Cord Blood (UCB) Transplantation." Blood 110, no. 11 (2007): 5065. http://dx.doi.org/10.1182/blood.v110.11.5065.5065.

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Abstract The hematopoietic cell transplantation (HCT)-specific comorbidity index (CI) has been shown to predict nonrelapse mortality (NRM) and overall survival (OS) after sibling and unrelated adult volunteer donor transplantation (Sorror Blood 2005, 106:2912). We retrospectively studied the predictive value of the HCT-CI in a cohort of 182 patients who underwent an umbilical cord blood (UCB) transplant for advanced or high risk malignancy at the University of Minnesota, between August 2001 and May 2006. Patients receive either a myeloablative (MA, n=54) or nonmyeloablative (NST, n=128) condit
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Steiger-Ronay, Valerie, Sebastian Stelz, David Steigmeier, Klaus Becker, Daniel B. Wiedemeier, and Thomas Attin. "Change of erosive potential of apple and orange juice at different dilutions." SWISS DENTAL JOURNAL SSO – Science and Clinical Topics 130, no. 1 (2020): 12–17. http://dx.doi.org/10.61872/sdj-2020-01-01.

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The aim of this in vitro study was to investigate the change of erosive properties of apple and orange juice after dilution with tap water. Apple juice, orange juice and citric acid were assessed for pH and titratable acidity at different aqueous dilutions (100% – pure liquid, 60% – 3 : 2 mixing ratio, and 40% – 2 : 3 mixing ratio respectively). Thus, 72 bovine enamel specimens were distributed to 9 groups (n = 8 specimens per group), followed by 25 minutes of erosion by superfusion with the described test liquids according to group allocation. Erosive substance loss (µm) was determined profil
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Remy, Katya, Chase Alston, Elyse Gonzales, et al. "Targeted Reinnervation During Gender-Affirming Mastectomy and Restoration of Sensation." JAMA Network Open 7, no. 11 (2024): e2446782. http://dx.doi.org/10.1001/jamanetworkopen.2024.46782.

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ImportanceDuring gender-affirming mastectomy, nerves are transected, resulting in sensory loss. Nerve preservation using targeted nipple-areola complex (NAC) reinnervation (TNR) may restore sensation.ObjectiveTo determine the quantitative and patient-reported sensory outcomes of TNR.Design, Setting, and ParticipantsProspective matched cohort study of patients undergoing gender-affirming mastectomy from August 2021 to December 2022 at Weill Cornell Medicine and Massachusetts General Hospital. Data were analyzed from January to March 2023.ExposurePatients who underwent TNR and matched patients w
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Abu-Khalaf, Maysa, Fnu Nikita, Ayako Shimada, et al. "Abstract P4-11-32: Change in body mass index in breast cancer survivors." Cancer Research 82, no. 4_Supplement (2022): P4–11–32—P4–11–32. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-11-32.

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Abstract Background: Obesity is associated with an increased risk of breast cancer recurrence and poor survival. Obesity rate in adults in the city of Philadelphia is high, with non-Hispanic blacks and Hispanics having the highest rates. We sought to evaluate changes in body mass index (BMI) in breast cancer survivors within the first 2 years from initial encounter for a breast cancer (BC) diagnosis (dx), and investigate factors that may correlate with a change in BMI. Methods: We identified 5,423 BC patients (pts) in our electronic medical record, (1/2015-present), using ICD-10 code C50.X. We
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Zimmer, A., A. Klein та G. Horneff. "SAT0491 PSORIASIS ASSOCIATED WITH MONOCLONAL-ANTIBODY-TNF-Α INHIBITORS VS. FUSION PROTEIN ETANERCEPT IN JUVENILE IDIOPATHIC ARTHRITIS PATIENTS - ANALYSIS OF THE BIKER REGISTRY". Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1202.1–1202. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4883.

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Background:Although efficacy of Tumor necrosis factor inhibitors (TNFi) for treatment of psoriasis is well established, patients may develop psoriasis for the first time while on TNFi as a paradoxical effect. Few data are available in patients with juvenile idiopathic arthritis (JIA).Objectives:To analyze the incidence of psoriasis in TNFi – treated JIA patients and to identify associated factors.Methods:Safety data from patients registered in the German Biologics registry (BIKeR) were analyzed. Cohorts of patients were grouped by treatment: any or multiple TNFi, single TNFi, biologics other t
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Radak, Djordje J., Nenad S. Ilijevski, Dragoslav Nenezic, et al. "Temporal Trends in Eversion Carotid Endarterectomy for Carotid Atherosclerosis: Single-Center Experience with 5,034 Patients." Vascular 15, no. 4 (2007): 205–10. http://dx.doi.org/10.2310/6670.2007.00046.

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The aim of this article is to review our experience in surgical treatment of carotid atherosclerosis using eversion carotid endarterectomy (ECEA) in 5,034 patients, with particular attention to temporal changes in patients' characteristics, diagnostic approach, surgical technique, medical therapy, and outcome in the early (group A, 1991–1997) versus late (group B 1998–2004) period of ECEA. From January 1991 to December 2004, 5,034 primary ECEAs were performed for high-grade carotid stenosis. Patients treated for restenosis after previous carotid surgery were excluded from the analysis. Group A
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Dionne-Odom, J. Nicholas, Andres Azuero, Kathleen Lyons, et al. "Benefits of immediate versus delayed palliative care to informal family caregivers of persons with advanced cancer: Outcomes from the ENABLE III randomized clinical trial." Journal of Clinical Oncology 32, no. 18_suppl (2014): LBA9513. http://dx.doi.org/10.1200/jco.2014.32.18_suppl.lba9513.

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LBA9513 Background: Family caregivers of individuals with advanced cancer experience significant burden and diminished QOL; few interventions have been found to reduce these outcomes. Methods: Randomized clinical trial conducted from 10/11/2010 to 9/5/2013 of immediate versus delayed (initiated 12 weeks after randomization) entry patients (n=207) and caregivers (n=122) into ENABLE (Educate, Nurture, Advise, Before Life Ends), a phone-based concurrent oncology palliative care intervention. QOL (Caregiver Quality of Life-Cancer, lower scores=better QOL), depression (Center for Epidemiological St
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Kang, Lixin, Xiaomei Ma, Nikolai A. Podoltsev, Jessica M. Stempel, and Rong Wang. "Abstract B115: Racial and ethnic disparities in the incidence and mortality trends of acute myeloid leukemia in the United States." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): B115. http://dx.doi.org/10.1158/1538-7755.disp23-b115.

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Abstract Introduction Acute myeloid leukemia (AML) is the most common type of leukemia among adults and carries a poor prognosis. This study aimed to assess the temporal trends of AML incidence and mortality for different racial and ethnic groups in the United States (US). Methods We obtained data on AML incidence and mortality (years 1999-2019) for all 50 states and the District of Columbia from the US Cancer Statistics database maintained by the Centers for Disease Control and Prevention. Using the JoinPoint regression program, we calculated the annual percent change (APC), average annual pe
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Xun, Helen, Waverley He, Jonlin Chen, Scott Sylvester, Sheera F. Lerman, and Julie Caffrey. "Characterization and Comparison of the Utilization of Facebook Groups Between Public Medical Professionals and Technical Communities to Facilitate Idea Sharing and Crowdsourcing During the COVID-19 Pandemic: Cross-sectional Observational Study." JMIR Formative Research 5, no. 4 (2021): e22983. http://dx.doi.org/10.2196/22983.

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Background Strict social distancing measures owing to the COVID-19 pandemic have led people to rely more heavily on social media, such as Facebook groups, as a means of communication and information sharing. Multiple Facebook groups have been formed by medical professionals, laypeople, and engineering or technical groups to discuss current issues and possible solutions to the current medical crisis. Objective This study aimed to characterize Facebook groups formed by laypersons, medical professionals, and technical professionals, with specific focus on information dissemination and requests fo
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Souza, Leandro de Pádua, Reginaldo Gomes Nobre, Hans Raj Gheyi, Reynaldo Teodoro De Fátima, Geovani Soares de Lima, and Genilson Lima Diniz. "ÍNDICES FISIOLÓGICOS E CRESCIMENTO DE PORTA-ENXERTOS DE CAJUEIRO SOB ESTRESSE SALINO E CONCENTRAÇÕES DE PROLINA." IRRIGA 1, no. 1 (2021): 169–83. http://dx.doi.org/10.15809/irriga.2021v1n1p169-183.

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ÍNDICES FISIOLÓGICOS E CRESCIMENTO DE PORTA-ENXERTOS DE CAJUEIRO SOB ESTRESSE SALINO E CONCENTRAÇÕES DE PROLINA LEANDRO DE PÁDUA SOUZA1; REGINALDO GOMES NOBRE2; HANS RAJ GHEYI1; REYNALDO TEODORO DE FATIMA1; GEOVANI SOARES DE LIMA1 E GENILSON LIMA DINIZ3 1 Programa de Pós-Graduação em Engenharia Agrícola, Universidade Federal de Campina Grande, Aprígio Veloso, 882, Universitário, 58428-830, Campina Grande, Paraíba, Brasil. E-mail:. engenheiropadua@hotmail.com; hans@agriambi.com.br; reynaldo.t16@gmail.com; geovanisoareslima@gmail.com 2 Departamento de Ciências e Tecnologia (DCT), Universidade Fe
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Tegegne, A., P. O. Osuji, A. Lahlou-Kassi, and E. Mukasa-Mugerwa. "Effect of dam nutrition and suckling on lactation in Borana cows and growth in their Borana × Friesian crossbred calves in an early weaning system in Ethiopia." Animal Science 58, no. 1 (1994): 19–24. http://dx.doi.org/10.1017/s0003356100007030.

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AbstractForty-four Borana × Friesian F1 crossbred calves born to Borana (Bos indicus) cows were randomly assigned to either suck their dams hvice daily or bucket-feeding with 1341 milk over a 57-day pre-weaning period. Their dams were also allocated either to a supplement group with grass hayad libitumand 5 kg per head per day of a concentrate ration or to an unsupplemented group withad libitumgrass hay only. Calves were fed in individual boxes in a calf house. The mean birth weight of calves was 24·8 (s.e. 1·8) kg. Suckled calves were heavier (P < 0·01) at weaning (47·7 (s.e. 1·9) v.37·1 (
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Eichhorn, Astrid, Aaron Held, and Philipp-Vincent Johannsen. "Universal signatures of singularity-resolving physics in photon rings of black holes and horizonless objects." Journal of Cosmology and Astroparticle Physics 2023, no. 01 (2023): 043. http://dx.doi.org/10.1088/1475-7516/2023/01/043.

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Abstract Within quantum-gravity approaches and beyond, different mechanisms for singularity resolution in black holes exist. Under a set of assumptions that we spell out in detail, these mechanisms leave their imprint in shadow images of spherically symmetric black holes. We find that even current EHT accuracy is sufficient to place nontrivial constraints on the scale of new physics within one modified spacetime, if the EHT measurement of M87* is combined with an independent measurement of the black-hole mass. In other spacetimes, increased accuracy is required that the next-generation EHT may
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Al-Kaisey, Ahmed M., Ramanathan Parameswaran, Christina Bryant, et al. "Atrial Fibrillation Catheter Ablation vs Medical Therapy and Psychological Distress." JAMA 330, no. 10 (2023): 925. http://dx.doi.org/10.1001/jama.2023.14685.

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ImportanceThe impact of atrial fibrillation (AF) catheter ablation on mental health outcomes is not well understood.ObjectiveTo determine whether AF catheter ablation is associated with greater improvements in markers of psychological distress compared with medical therapy alone.Design, Setting, and ParticipantsThe Randomized Evaluation of the Impact of Catheter Ablation on Psychological Distress in Atrial Fibrillation (REMEDIAL) study was a randomized trial of symptomatic participants conducted in 2 AF centers in Australia between June 2018 and March 2021.InterventionsParticipants were random
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Sanai, Nader, Zaman Mirzadeh, and Michael T. Lawton. "Supracerebellar-Supratrochlear and Infratentorial-Infratrochlear Approaches." Operative Neurosurgery 66, suppl_2 (2010): ons264—ons274. http://dx.doi.org/10.1227/01.neu.0000369653.12185.fd.

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Abstract OBJECTIVE Lateral supracerebellar-infratentorial approaches are established for lesions in ambient cistern and posterolateral midbrain, but published surgical experiences do not describe results with this approach in the sitting position. Gravity retraction of the cerebellum opens this surgical corridor and dramatically alters exposure, creating 2 variations of the lateral supracerebellar-infratentorial approach: the supracerebellar-supratrochlear approach and the infratentorial-infratrochlear approach. METHODS We reviewed our experience treating cavernous malformations and arterioven
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TRAORE, Kalifa. "Role of Blood Transfusion in the Management of Obstetric Emergencies in the Gynaecology-Obstetrics Department of Gao Hospital (Mali)." Greenfort International Journal of Applied Medical Science 1, no. 1 (2023): 19–27. http://dx.doi.org/10.62046/gijams.2023.v01i01.005.

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The aim was to evaluate the role of blood transfusion in the management of obstetric emergencies in the gynaecology and obstetrics department at Gao Hospital. Materials and methods: This was a prospective, descriptive, cross-sectional, analytical study from January 01 to June 30, 2020, i.e. a period of six (06) months in the gynecology-obstetrics department at Gao Hospital. Results: We recorded 536 cases of obstetric emergencies, of which 120 cases required emergency blood transfusion, i.e. 22.39%. The 20-29 age group was the most affected with an average age of 26.5 years. The extremes were 1
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Ghenim, A., I. Kacem, A. Chouchane, et al. "The neuro-psychological manifestations of COVID-19 in healthcareworkers." European Psychiatry 67, S1 (2024): S149—S150. http://dx.doi.org/10.1192/j.eurpsy.2024.334.

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IntroductionAt the beginning of the Covid-19 pandemic, respiratory expression of SARS-CoV-2 infection was the most worrying one. Later, other symptoms appeared to be more disturbing such as neurological and psychiatric manifestations, which may be due to direct or indirect effects of this virus on the central nervous system.ObjectivesTo assess the prevalence of neuropsychological manifestations of covid-19 in healthcareworkers and to identify their risk factors.MethodsThis is a cross-sectional descriptive epidemiological study, carried out in the teaching hospitals of Farhat Hached and Sahloul
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Zureigat, Hadil, Ahmed N. Mohamed, Muaz Alsabbagh Alchirazi, et al. "Cardiovascular Profile of Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia: A 16-Year Observational Study." Blood 144, Supplement 1 (2024): 1777. https://doi.org/10.1182/blood-2024-212146.

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Background: Chronic myelogenous leukemia (CML) is caused by a chromosomal translocation that gives rise to a chimeric BCR-ABL protein with constitutive tyrosine kinase (TK) activity. Tyrosine kinase inhibitors (TKIs) block this protein and have thus led to a paradigm shift in CML management in the early 2000s. Despite TKIs' efficacy in CML, their cardiotoxic side effects are a clinical challenge. This may result in TKI discontinuation and ultimately suboptimal response. Hence, we aim to explore the cardiotoxicity profile of TKIs, adjusting for pre-existing cardiovascular risk factors. Methods:
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Rhind, S. M., B. A. Morris, Jill Clayton, and G. Gittus. "Effect of level of food intake at mating on the reproductive performance of ewes passively immunized against testosterone." Animal Science 45, no. 1 (1987): 81–85. http://dx.doi.org/10.1017/s0003356100036655.

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AbstractIn a 2 × 2 × 2 experiment, 296 Scottish Blackface ewes were fed to achieve one of two levels of body condition (high: condition scores ^2·75; low: condition scores ^2·50) by 2 weeks before joining with rams. Half of the ewes of each condition score were fed dried grass pellets ad libitum and 300 g hay per head daily, between 2 weeks before and 8 days after joining, while the remaining ewes were offered a live-weight maintenance ration comprising 750 g pellets and 400 g hay per head daily. From 8 days after joining the intake of all ewes was gradually changed, over a 2-week period, to 1
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Dowling, Michael M., Charles T. Quinn, Patricia Plumb, et al. "Acute silent cerebral ischemia and infarction during acute anemia in children with and without sickle cell disease." Blood 120, no. 19 (2012): 3891–97. http://dx.doi.org/10.1182/blood-2012-01-406314.

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Abstract We hypothesized that the silent cerebral infarcts (SCI), which affect up to 40% of children with sickle cell disease (SCD), could occur in the setting of acute anemic events. In a prospective observational study of children with and without SCD hospitalized for an illness associated with acute anemia, we identified acute silent cerebral ischemic events (ASCIE) in 4 (18.2%) of 22 with SCD and in 2 (6.7%) of 30 without SCD, using diffusion-weighted magnetic resonance imaging. Children with ASCIE had lower hemoglobin concentration than those without (median 3.1 vs 4.4 g/dL, P = .003). Th
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Gadalla, Yousef H., Somak Chaudhuri, Sean G. Kraus, et al. "Abstract 7307: Potential role of alpha-2-macroglobulin in versican proteolysis regulation in colorectal cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 7307. https://doi.org/10.1158/1538-7445.am2025-7307.

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Abstract Background: Versican is a large extracellular glycoprotein that acts as a barrier for immune cell infiltration in colorectal cancer (CRC). The V1 isoform of versican can be cleaved by ADAMTS 4 and 5 into the bioactive fragment versikine with immune stimulatory properties. Despite overexpression of ADAMTS 4 and 5 in CRC, versican may be poorly proteolyzed. ADAMTS 4 and 5 may be inhibited by the presence of an extracellular endopeptidase inhibitor, alpha 2 macroglobulin (A2M). Here we investigate A2M expression in CRC, its correlation with versican proteolysis status, and immune cell in
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36

Kantathut, Narongrit, Piya Cherntanomwong, Siam Khajarern, and Parinya Leelayana. "Lactated Ringer’s as a Base Solution for del Nido Cardioplegia." Journal of ExtraCorporeal Technology 51, no. 3 (2019): 153–59. http://dx.doi.org/10.1051/ject/201951153.

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Unavailability of Plasma-Lyte A precludes the utility of traditional del Nido cardioplegia in many countries. This observational study aimed to evaluate myocardial preservation and clinical outcomes when using lactated Ringer’s solution as the base solution for del Nido cardioplegia as compared with our institute’s standard blood cardioplegia strategy. Eighty-nine adult patients underwent cardiac surgery for acquired heart disease from February 2017 to November 2017 either with del Nido cardioplegia (n = 44) or blood cardioplegia (n = 45). Clinical data and outcomes were compared. Patient char
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Ahmed, Gias Uddin, Md Mamunur Rahman, Mohammad Nurul Alam, Md Badrul Alam, and Baadruzzoha Sarker. "Impact of stocking density on growth and production performance of Vietnamese koi (Anabas testudineus) in semi-intensive culture system at Muktaghasa region of Mymensingh district." Research in Agriculture Livestock and Fisheries 2, no. 2 (2015): 335–41. http://dx.doi.org/10.3329/ralf.v2i2.25019.

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Stocking density is considered one of the important factors affecting fish growth. The study was aimed to compare the growth parameters of Vietnamese Koi (Anabas testudineus ) at various stocking densities. The experiment was carried out during the period from 01 September to 30 November 2014. Three stocking densities were used as 150, 250 and 350 fries/dec and designated as treatment T1, T2 and T3 respectively each having two replicates. The average size of each pond was 33 decimal with an average depth of 5 feet. Quality fish feed was used three times daily throughout the culture period. Fro
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Kim, Young Hyo, Beom Joon Kim, Kang Hyun Bang, Yoonseok Hwang, and Tae Young Jang. "Septoplasty Improves Life Quality Related to Allergy in Patients with Septal Deviation and Allergic Rhinitis." Otolaryngology–Head and Neck Surgery 145, no. 6 (2011): 910–14. http://dx.doi.org/10.1177/0194599811424119.

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Objective. Evaluate the effect of septoplasty on the clinical course of allergic rhinitis by comparing (1) symptom change using the Visual Analogue Scale (VAS), (2) change of the medication score, and (3) improvement of the quality of life using a questionnaire. Study Design. Prospective pilot. Setting. Academic tertiary rhinological practice. Subjects and Methods. Sixty-two patients who had undergone septoplasty and turbinoplasty for septal deviation and allergic rhinitis were enrolled in group A. Twenty-six patients who had undergone only turbinoplasty for allergic rhinitis were enrolled in
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Visvanathan, Renuka, Michael Horowitz, and Ian Chapman. "The hypotensive response to oral fat is comparable but slower compared with carbohydrate in healthy elderly subjects." British Journal of Nutrition 95, no. 2 (2006): 340–45. http://dx.doi.org/10.1079/bjn20051633.

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The objective of the present study was to determine the comparative hypotensive responses to drinks containing predominantly fat and carbohydrate (CHO) in healthy elderly subjects. Using a randomised, cross-over study, the participants, twelve elderly subjects, six of them female (72·2 (sd 5·7) years), were investigated. On three separate days, blood pressure (BP) and heart rate were measured following ingestion of 300ml drinks containing: (1) CHO (75g glucose and 93g Polyjoule (CHO polymer) providing 2732kJ (653kcal)); (2) 88% fat (cream blended with milk providing 2732kJ (653kcal)); (3) wate
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40

DeVries, J. Hans, Luigi Meneghini, Anthony H. Barnett, et al. "A Patient-level Analysis of Efficacy and Hypoglycaemia Outcomes Across Treat-to-target Trials with Insulin Glargine Added to Oral Antidiabetes Agents in People with Type 2 Diabetes." European Endocrinology 10, no. 1 (2010): 23. http://dx.doi.org/10.17925/ee.2014.10.01.23.

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Background:A better understanding of hypoglycaemia risk when insulin is used in combination with one or more oral antidiabetes agents may assist in the treatment decision-making process for the clinician and address concerns regarding hypoglycaemia when initiating or intensifying insulin therapy. The objective of this study was to analyse efficacy and hypoglycaemia outcomes in people with type 2 diabetes receiving insulin glargine (IG) with metformin (MET), sulphonylurea (SU) or MET+SU.Methods:Patient-level data were pooled from 15 randomised, treat-to-target trials (fasting plasma glucose [FP
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41

Pfeiffer, Alixandria F., Nathalie H. Chang, John J. Byrne, Michael Berkus, and Nora M. Doyle. "Intravenous Iron Supplementation in Pregnancy: Comparisons of Dosage and Latency of Infusion Based on a Quality Improvement Project on Maternal Transfusion Reduction [ID 2683380]." Obstetrics & Gynecology 143, no. 5S (2024): 33S. http://dx.doi.org/10.1097/01.aog.0001013380.26033.de.

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INTRODUCTION: Optimal dosing of intravenous iron supplementation (IVFe) and latency of the infusion for pregnant patients with iron deficiency anemia has been minimally evaluated. We analyzed the effects of specific IVFe dosage parameters as part of an institution-based protocol on maternal peripartum hemoglobin (Hb) levels stratifying by time of infusion to delivery. METHODS: We reviewed average changes in maternal Hb pre-infusion and pre-delivery over a 3-year period (2020–2023) after the implementation of a maternal transfusion reduction bundle was incorporated at our Level IV maternal care
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Schmitt, Kenneth, Joseph Tafalla, Richard Wells, and Joseph Rinehart. "Anesthetic management of a parturient with Ebstein anomaly palliated with Fontan procedure." Anaesthesia, Pain & Intensive Care 29, no. 2 (2025): 341–44. https://doi.org/10.35975/apic.v29i2.2724.

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Women of childbearing age with surgically palliated congenital heart disease (CHD) have become increasingly common as survival rates of CHD improve. We describe a 33-year-old female with a history of Ebstein anomaly (EA), status post fenestrated lateral tunnel Fontan procedure, at gestational week 37 who presented for induction of labor and was found to have a fetal breech presentation. Cesarean section with general anesthesia was indicated after failure to progress in labor with epidural analgesia. As surgically treated EA has led to increased survivability, further discussion on the anesthet
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Rahman, Fahd, Roy N. Gay, Samir K. Ballas, et al. "Predictors of Adverse Outcomes in Hospitalized Adult Patients with Sickle Cell Disease." Blood 106, no. 11 (2005): 3197. http://dx.doi.org/10.1182/blood.v106.11.3197.3197.

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Abstract The identification of patients with sickle cell disease at risk of serious complications at the time of hospital admission can help stratify patients who will need aggressive management. We identified predictors associated with adverse outcomes such as frequent hospitalizations, acute pain crises and acute chest syndromes. To that end, we retrospectively reviewed medical records of 265 adult sickle cell disease patients, hospitalized between 1/1/98 and 2/3/05 at Mercy Catholic Medical Center, with complete clinical and laboratory data. 195/73.6% had HbSS and the rest had HbSC, HbSβ-th
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Peixoto, Maria Claudia, Giselle F. Taboada, Márcia B. Wagman, et al. "Avaliação da incidência e do comportamento do câncer de tireóide em pacientes com doença de graves submetidos a tireoidectomia." Arquivos Brasileiros de Endocrinologia & Metabologia 47, no. 5 (2003): 566–71. http://dx.doi.org/10.1590/s0004-27302003000500010.

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A fim de avaliar a incidência, comportamento, evolução clínica e determinação de possíveis fatores preditivos da associação entre carcinoma de tireóide (CT) e Doença de Graves (DG), analisamos os prontuários de todos os pacientes submetidos à tireoidectomia para tratamento definitivo de DG em 2 hospitais universitários, entre 01/79 e 11/02. Dos 341 pacientes identificados, o exame histológico das peças cirúrgicas revelou CT em 7 (2,1%). A idade dos pacientes do grupo sem CT variou de 13 a 79 anos (mediana: 34) e naqueles com CT variou de 19 a 50 anos (mediana: 29), sem diferença significativa
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45

Newton, Kathryn T., and Aaron Ashley. "Introducing the Interdisciplinary Nature of Health Care Through Case Study Models." Journal of Education and Training Studies 8, no. 1 (2019): 20. http://dx.doi.org/10.11114/jets.v8i1.4600.

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Interprofessional education (IPE) is a critical area needed to improve the quality of healthcare. Stereotypes of other disciplines persist by healthcare workers, limiting the ability to work as a team. Knowledge of roles of healthcare professions is a key competency of IPE. An online, 12-week course was developed to introduce students to the interdisciplinary nature of healthcare through case study models. Through built-in links, students explore medical terminology, diagnostic testing, pathophysiology, treatment, and health professionals who work as a team to diagnose and treat the patient. A
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46

Gulati, Uday, Christine Medeiros, Ananya Nanduri, et al. "Understanding Pneumomediastinum as a Complication in Patients With COVID-19: A Case Series." Journal of Investigative Medicine High Impact Case Reports 10 (January 2022): 232470962211271. http://dx.doi.org/10.1177/23247096221127117.

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Pneumomediastinum is a rare complication among non-coronavirus patients but has been published with increased incidence in patients positive for SARS-CoV-2 infection. Most of these studies report patients on mechanical ventilation and an understanding of mechanisms causing this remains limited. We aim to use an increasing occurrence in patients not on mechanical ventilation to further explore mechanisms that predispose patients to pneumomediastinum and to assess characteristics potentially related to poor outcomes. We report a case series of 37 patients diagnosed with COVID-19 and pneumomedias
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47

Demark-Wahnefried, Wendy, Robert A. Oster, Kerry P. Smith, et al. "Vegetable Gardening and Health Outcomes in Older Cancer Survivors." JAMA Network Open 7, no. 6 (2024): e2417122. http://dx.doi.org/10.1001/jamanetworkopen.2024.17122.

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ImportanceCancer survivors experience accelerated functional decline that threatens independence and quality of life. Previous studies have suggested that vegetable gardening may improve diet, physical activity, and physical function in this vulnerable population, which comprises more than 5% of the US population.ObjectiveTo assess whether diet, physical activity and functioning, and other outcomes improved in older cancer survivors assigned to a vegetable gardening intervention compared with a waitlist.Design, Setting, and ParticipantsFrom May 11, 2016, to May 2, 2022, a 2-arm, assessor-blind
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48

Álvarez-Reguera, C., J. J. Gaitán-Valdizán, R. Fernández-Ramón, et al. "OP0091 TREATMENT OF OCULAR SARCOIDOSIS. STUDY OF 65 PATIENTS OF A SERIES OF 384 PATIENTS FROM A SINGLE UNIVERSITY HOSPITAL." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 50.1–50. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1896.

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Background:Ocular involvement is a relatively frequent and potentially severe complication of sarcoidosis. Oral corticosteroids (OCS) are the first-line treatment. Conventional immunosuppressive agents (cIS) and biological therapy (BT) can be used in refractory cases (1-5).Objectives:To evaluate the treatment and visual outcomes of a cohort of patients diagnosed with ocular sarcoidosis.Methods:Study of a large cohort (n=384) of all consecutive patients diagnosed with sarcoidosis from January 1, 1999 to December 31, 2019 at a single University Hospital. Finally, 344 patients were included accor
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Sasahara, Chihoko, Stephen F. Burns, Masashi Miyashita, and David J. Stensel. "Beneficial effects of combined olive oil ingestion and acute exercise on postprandial TAG concentrations in healthy young women." British Journal of Nutrition 108, no. 10 (2012): 1773–79. http://dx.doi.org/10.1017/s0007114511007380.

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Foods high in monounsaturated fat, such as olive oil, and endurance exercise are both known to independently reduce postprandial TAG concentrations. We examined the combined effects of exercise and dietary fat composition on postprandial TAG concentrations in nine healthy pre-menopausal females (age 26·8 (sd 3·3) years, BMI 22·3 (sd 2·0) kg/m2). Each participant completed four, 2 d trials in a randomised order: (1) butter–no exercise, (2) olive oil–no exercise, (3) butter–exercise, (4) olive oil–exercise. On day 1 of the exercise trials, participants walked or ran on a treadmill for 60 min. On
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Vrooman, Lynda M., Donna S. Neuberg, Kristen E. Stevenson, Jeffrey G. Supko, Stephen E. Sallan, and Lewis B. Silverman. "Dexamethasone and Individualized Asparaginase Dosing Are Each Associated with Superior Event-Free Survival in Childhood Acute Lymphoblastic Leukemia: Results From DFCI-ALL Consortium Protocol 00-01." Blood 114, no. 22 (2009): 321. http://dx.doi.org/10.1182/blood.v114.22.321.321.

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Abstract Abstract 321 BACKGROUND: The DFCI-ALL Consortium Protocol 00-01 aimed to determine the relative efficacy and toxicity of 1) dexamethasone (DEX) vs. prednisone (PRED) and 2) asparaginase (ASP) with individualized dosing (ID) based on pharmacokinetic measurements vs. standard fixed dosing (FD) based on body surface area, in the treatment of children with newly diagnosed acute lymphoblastic leukemia (ALL). PATIENTS and METHODS: Between 2000 and 2004, 492 eligible patients (pts) ages 1-18 years (yrs) with newly diagnosed ALL enrolled on Protocol 00-01 from 10 institutions. 282 pts were st
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