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Journal articles on the topic '346:06.03 (043.2)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Finkenstedt, Gerd, Rudolf W. Gasser, Günter Höfle, Christine Watfah, and Leo Fridrich. "Effects of growth hormone (GH) replacement on bone metabolism and mineral density in adult onset of GH deficiency: results of a double-blind placebo-controlled study with open follow-up." European Journal of Endocrinology 136, no. 3 (1997): 282–89. http://dx.doi.org/10.1530/eje.0.1360282.

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Abstract It is known that GH stimulates bone turnover and that GH-deficient adults have a lower bone mass than healthy controls. In order to evaluate the influences of GH replacement therapy on markers of bone turnover and on bone mineral density (BMD) in patients with adult onset GH deficiency, a doubleblind placebo-controlled study of treatment with recombinant human GH (rhGH; mean dose 2·4 IU daily) in 20 patients for 6 months and an extended open study of 6 to 12 months were conducted. Eighteen patients, fourteen men and four women, with a mean age of 44 years with adult onset GH deficienc

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Cooper, Odelia, and Sungjin Kim. "ODP643 Metabolic Effects of Growth Hormone Replacement in Craniopharyngioma and Pituitary Adenoma Patients: Analysis of the Hypopituitary Control and Complications Study (HypoCCS) Database." Journal of the Endocrine Society 6, Supplement_1 (2022): A521. http://dx.doi.org/10.1210/jendso/bvac150.1085.

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Abstract Introduction Craniopharyngioma (CP) is a rare, parasellar tumor associated with metabolic dysfunction and panhypopituitarism. We investigated the impact of growth hormone (GH) replacement on metabolic complications in patients with adult-onset CP or pituitary adenoma (PA) using data collected between 1996 and 2012 in HypoCCS, an open-label, global prospective surveillance study of GH replacement in GH deficiency. Methods GH-treated (≥6 months) vs untreated groups in CP and PA patients were compared using ANOVA or Wilcoxon rank-sum test for continuous variables and chi-square test or F

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Maria, Dely. "Penerapan senam kaki dan modifikasi diit dalam pengontrolan kadar gula darah melalui metode studi kasus." Jurnal Kesehatan Holistic 3, no. 1 (2019): 31–45. http://dx.doi.org/10.33377/jkh.v3i1.43.

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Perubahan pola penyakit dari penyakit infeksi ke penyakit tidak menular (PTM) merupakan faktor utama masalah morbiditas dan mortalitas. Menurut WHO (2013), 80% penderita DM berasal dari negara berkembang salah satunya Indonesia. Berdasarkan hasil data Riskesdas (2013), 5,7% di Indonesia khususnya Jakarta timur yang terkena DM dari usia 15 tahun memiliki prevalensi sebesar 2,4%. Berbagai masalah dapat timbul bila diabetes melitus tidak ditangani seperti neuropati dan retinopati. Metode yang digunakan yaitu studi kasus. Studi kasus dilakukan pada 2 pasien DM yang mengalami ketidakefektifan perfu

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Ashor, Ammar W., Mario Siervo, Jose Lara, Clio Oggioni, Sorena Afshar, and John C. Mathers. "Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials." British Journal of Nutrition 113, no. 8 (2015): 1182–94. http://dx.doi.org/10.1017/s0007114515000227.

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Randomised controlled trials (RCT) testing the effects of antioxidant supplements on endothelial function (EF) have reported conflicting results. We aimed to investigate the effects of supplementation with antioxidant vitamins C and E on EF and to explore factors that may provide explanations for the inconsistent results. We searched four databases (MEDLINE, Embase, Cochrane Library and Scopus) from inception until May 2014 for RCT involving adult participants aged ≥ 18 years who were supplemented with vitamins C and E alone or in combination for more than 2 weeks and reporting changes in EF m

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White, Deborah, Phuong Dang, Amity Venables, et al. "ABCB1 Overexpression May Predispose Imatinib Treated CML Patients to the Development of Abl Kinase Domain Mutations, and May Be an Important Contributor to Acquired Resistance." Blood 108, no. 11 (2006): 2144. http://dx.doi.org/10.1182/blood.v108.11.2144.2144.

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Abstract Imatinib has resulted in excellent and sustained clinical response in most patients with CML. For a few patients, a treatment limitation has been the development of imatinib resistance, frequently the result of kinase domain mutations. The cause of increased susceptibility to mutation development remains unknown. ABCB1 is a recognized efflux transporter of imatinib. Previous studies have demonstrated high ABCB1 expression in imatinib resistant cell lines. We hypothesize that ABCB1, by facilitating drug efflux and therefore limiting the intracellular concentration of imatinib, may cont

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Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a

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Kosmadopoulos, Anastasi, Philippe Boudreau, and Diane Boivin. "285 Pilot field study of Ambulatory Sleep-Staging in Shift-Working Air Traffic Controllers." Sleep 44, Supplement_2 (2021): A114. http://dx.doi.org/10.1093/sleep/zsab072.284.

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Abstract Introduction The simplicity of wrist actigraphy for sleep-wake monitoring in the field contributes to its ubiquity in shift-work research. However, devices based solely on recording activity levels are generally not suitable to quantify sleep architecture. This is a limitation as quantifying changes in sleep stages caused by circadian misalignment is important to better assess the consequences of sleep-wake disruption in shift-working populations. This pilot study was conducted to evaluate whether sleep stages vary with respect to different shift types. Methods Six male air traffic co

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Brunstein, Claudio G., Juliet N. Barker, Todd E. DeFor, Kathy French, Daniel J. Weisdorf, and John E. Wagner. "Non-Myeloablative (NMA) Umbilical Cord Blood Transplantation (UCBT): Promising Disease-Free Survival in 95 Consecutive Patients." Blood 106, no. 11 (2005): 559. http://dx.doi.org/10.1182/blood.v106.11.559.559.

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Abstract Conventional allogeneic hematopoietic stem cell transplantation (HSCT) is limited by lack of rapidly available HLA-matched donors and excess transplant-related mortality (TRM). Therefore, we investigated the use of unrelated UCBT after NMA conditioning in patients (pts) with high-risk hematologic malignancy. From 10/01 to 06/05, 95 consecutive adults [median age 50 yrs (range 18-69), median weight 78 kg (range 50-134)] received a NMA prior to UCBT. Pts were eligible if aged &gt;45 yrs (n=70; 74%), or had extensive prior therapy (n=25; 26% with 17 having had a prior autologous HSCT

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Warmansyah, Jhoni, Restu Yuningsih, Evi Selva Nirwana, et al. "The Effect of Mathematics Learning Approaches and Self-Regulation to Recognize the Concept of Early Numbers Ability." JPUD - Jurnal Pendidikan Usia Dini 17, no. 1 (2023): 54–81. http://dx.doi.org/10.21009/jpud.171.05.

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The ability to recognize the concept of early numbers in early childhood is very important to develop so that children are ready to take part in learning mathematics at a higher level. This study aims to determine the effect of mathematics learning approaches and self-regulation to recognize the concept of early numbers ability in kindergarten. The study used an experimental method with a treatment design by level 2x2. The sample used was 32 children. Score data, ability to recognize number concepts, analyzed and interpreted. The results showed that: (1) The Realistic Mathematics Education app

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Tuzzahroh, Fatimah, and Sugiyarti Fatma Laela. "Sharia Audit and Shariah Compliance of Islamic Financial Institutions: A Bibliometric Analysis." Jurnal Ekonomi Syariah Teori dan Terapan 9, no. 6 (2022): 815–33. http://dx.doi.org/10.20473/vol9iss20226pp815-833.

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ABSTRAK Penelitian ini bertujuan untuk memetakan penelitian-penelitian sebelumnya tentang audit syariah dan perannya dalam meningkatkan kepatuhan syariah di lembaga keuangan syariah (LKS). Penelitian ini juga menguraikan tantangan yang dihadapi oleh LKS dan solusi dalam mengimplementasikan audit syariah. Sebanyak 308 publikasi diperoleh dari database Google scholar, Emerald Insight, Research Gate, Crossref, Microsoft Academic and Pubmed yang diakses dengan perangkat lunak Publish or Perish (PoP) dalam kurun waktu 2008-2021. Studi ini menerapkan analisis bibliometrik menggunakan VOSviewer, yang

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Bashonga, Bishobibiri Alexis, Sande Eric, Ntakimazi Gaspard, and Kahindo Charles. "Bird Ecology in the Ruzizi Delta, Northern End of Lake Tanganyika in Burundi and in the Democratic Republic of Congo." Biolife 11, no. 1 (2023): 12–20. https://doi.org/10.5281/zenodo.7686228.

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<strong>Abstract</strong> Bird ecology in the Ruzizi Delta was investigated during the months of April, July and October 2019-2021. Three species of water birds were the most prominent, the Cattle Egret (Ardeidae), Bubulcus ibis (Linnaeus, 1758) «Héron garde boeufs», the Black Crake (Rallidae) Amaurornis flavirostris (Swainson, 1837) «Râle à bec jaune» and the Africana Jacana (Jacanidae) Actophilornis africanus (Gmelin, 1789) «Jacana a poitrine dorée». The objective pursued by the research is the sustainable conservation of birds b

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Blauvelt, Andrew, Emma Guttman-Yassky, Charles Lynde, et al. "Cendakimab in Patients With Moderate to Severe Atopic Dermatitis." JAMA Dermatology, July 17, 2024. http://dx.doi.org/10.1001/jamadermatol.2024.2131.

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ImportanceCendakimab selectively targets interleukin (IL)–13, a type 2 cytokine implicated in atopic dermatitis (AD) pathogenesis, by inhibiting binding to its receptors (IL13R-α1 and IL13R-α2). Proof-of-concept work in AD supports using cendakimab for type 2 inflammatory diseases.ObjectiveTo evaluate the efficacy and safety of cendakimab compared with placebo in patients with moderate to severe AD.Design, Setting, and ParticipantsThis phase 2, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging clinical trial was conducted from May 2021 to November 2022. Adult patients

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Ghosh, Shibani A., Nicholas R. Strutt, Gloria E. Otoo, et al. "A macro- and micronutrient-fortified complementary food supplement reduced acute infection, improved haemoglobin and showed a dose–response effect in improving linear growth: a 12-month cluster randomised trial." Journal of Nutritional Science 8 (2019). http://dx.doi.org/10.1017/jns.2019.18.

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AbstractInadequate protein quality may be a risk factor for poor growth. To examine the effect of a macronutrient–micronutrient supplement KOKO Plus (KP), provided to infants from 6 to 18 months of age, on linear growth, a single-blind cluster-randomised study was implemented in Ghana. A total of thirty-eight communities were randomly allocated to receive KP (fourteen communities, n 322), a micronutrient powder (MN, thirteen communities, n 329) and nutrition education (NE, eleven communities, n 319). A comparison group was followed cross-sectionally (n 303). Supplement delivery and morbidity w

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Du, Mengxi, and Fang Fang Zhang. "Dietary Supplement Use Among Adult Cancer Survivors in the United States." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.168.6.

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BackgroundMany cancer patients initiated supplement use after cancer diagnosis and yet the effect of supplement use on survival has not been established. The trend of and factors associated with dietary supplement use in cancer survivors warrant further investigation.MethodsWe examined the trend of dietary supplemental use in 1,902 adult cancer survivors who participated in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2012, and compared the frequency of supplement use in cancer survivors to that of 3,804 individuals with no history of cancer who were matched to th

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Moustafa, Muhamad. "A Comprehensive Review of Monoclonal Antibodies for the Treatment of Follicular Lymphoma Including Both Approved and Investigational Options." Medical Research Archives 11, no. 11 (2023). http://dx.doi.org/10.18103/mra.v11i11.4745.

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Follicular lymphoma (FL) is the most common type of indolent lymphoma in the Western world, accounting for approximately 30% of lymphoma cases. FL is known for its recurrent nature, necessitating diverse treatment options. The introduction of rituximab, an anti-CD20 antibody, has greatly improved FL outcomes and paved the way for targeted therapies. In this review, we thoroughly explore the structure, mechanism of action, clinical outcomes, and side effects of currently approved monoclonal antibodies (mAb) for FL. Furthermore, we provide insights into ongoing clinical trials and emerging monoc

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