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Journal articles on the topic '362.2/9'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Kamminga, Katherine L., Thomas P. Kuhar, Adam Wimer, and D. Ames Herbert. "Effects of the Insect Growth Regulators Novaluron and Diflubenzuron on the Brown Marmorated Stink Bug." Plant Health Progress 13, no. 1 (2012): 2. http://dx.doi.org/10.1094/php-2012-1212-01-rs.

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The brown marmorated stink bug (BMSB), Halyomorpha halys (Stål), is an invasive pest from China that causes economic damage to field crops, vegetables, and tree fruit. Due to its destructive potential, applications of broad-spectrum insecticides have escalated. Researchers are trying to identify options for controlling BMSB that have less of a negative impact on non-target species. Chitin biosynthesis inhibitors are more selective than the commonly used pyrethroids and organophosphates. They are active on the larval stage of the insect and are reported as having sublethal effects such as reduc

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Avdeeva, Natalya, Alexandr Kulikov, Mikhail Pokrovskii, and Tatyana Avtina. "PHARMACOKINETIC STUDIES OF NEW ANTIPARKINSONIAN DRUG RAPITALAM." Research Results in Pharmacology 2, no. (4) (2016): 3–8. https://doi.org/10.18413/2500-235X-2016-2-4-3-8.

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Parkinson's disease is the most common neurodegenerative disorder after Alzheimer's disease. The aim of this study was to investigate the pharmacokinetic parameters of the mGluR4 receptor blocker Rapitalam on rabbits. There was developed the method of the quantitative determination of Rapitalam in the blood plasma of rabbits using high performance liquid chromatography with tandem mass spectrometric detection. The study was performed on 12 rabbits (males, weighing between 3,300 to 3,500 g). In intragastric dosing of the substance was administered using a gastric tube in the form of suspension

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Rocha, Évilin, Larissa Bomfim, Sérgio Junior, Gustavo Santos, Cássio Meira, and Milena Soares. "Photodynamic Therapy with an Association of Methylene Blue and Toluidine Blue Promoted a Synergic Effect against Oral Squamous Cell Carcinoma." Cancers 15, no. 23 (2023): 5509. http://dx.doi.org/10.3390/cancers15235509.

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Among the most malignant cancers, oral squamous cell carcinoma (OSCC) stands out as the most common malignant head and neck tumor. Despite advances in the field of treatment, the prognosis of patients with OSCC remains poor. Aiming to overcome the limitations of the currently existing therapies against OSCC, the present work aims to investigate the potential of photodynamic therapy (PDT) with phenothiazine derivatives used alone or in combination. The incorporation of methylene blue (MB) and toluidine blue (TB) was evaluated in OSCC cell lines (HSC-3 and SCC-9) and a nontumor cell line (Hfib).

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Muntoni, Francesco, Isabelle Desguerre, Michela Guglieri, et al. "Ataluren use in patients with nonsense mutation Duchenne muscular dystrophy: patient demographics and characteristics from the STRIDE Registry." Journal of Comparative Effectiveness Research 8, no. 14 (2019): 1187–200. http://dx.doi.org/10.2217/cer-2019-0086.

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Aim: Strategic Targeting of Registries and International Database of Excellence (STRIDE) is an ongoing, multicenter registry providing real-world evidence regarding ataluren use in patients with nonsense mutation Duchenne muscular dystrophy (DMD) in clinical practice (NCT02369731). Here, we describe the initial demographic characteristics of the registry population. Patients & methods: Patients will be followed up from enrollment for ≥5 years or until study withdrawal. Results & conclusion: As of 9 July 2018, 213 DMD boys were enrolled from 11 countries. Mean (standard deviation) ages

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R Hadi, Najah, and Ahmed M Hasan. "Magnesium sulfate ameliorates cerebral ischemia reperfusion injury via interfering with inflammatory and oxidative pathways." American Journal of BioMedicine 4, no. 2 (2016): 187–202. http://dx.doi.org/10.18081/2333-5106/016-187-202.

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Magnesium sulfate has neuroprotective effects and decrease overall neuronal firing. It is also decrease firing of excitable tissues outside the brain. We study the anti-inflammatory and antioxidant effects of magnesium sulfate in rat brain following ischemia reperfusion (I/R) stress. Twenty four rats were grouped into 4 groups: The first (sham group), the second (control) and the third group(control-vehicle) and the forth (treated with Magnesium sulfate). Animals in the second group underwent bilateral common carotid artery ligation without treatment, whereas the forth group were injected with

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Al-Mudhafar, Ahmed MH. "The study of neuroprotective and anti-inflammatory effects of magnesium sulfate in rats following cerebral ischemia reperfusion injury." Kufa Journal For Veterinary Medical Sciences 5, no. 1 (2014): 1–10. http://dx.doi.org/10.36326/kjvs/2014/v5i14208.

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Background and objective: Magnesium sulfate has neuroprotective effects and decrease overall neuronal firing. It is also decrease firing of excitable tissues outside the brain. It is not known whether this neuroprotective effect is due to antioxidant effect, anti-inflammatory or other mechanism. In this research we study the anti-inflammatory effect of magnesium sulfate in rat brain following ischemia reperfusion stress.Material and methods: Twenty four rats were grouped into 4 groups: The first (sham group), the second (control) and the third group(control-vehicle) and the forth (treated with

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Heying, Birgit, Ute Ch Rodewald, and Bernard Chevalier. "The Stannides RE2Ni2Sn (RE = Pr, Ho, Er, Tm) – Structural Transition from the W2B2Co to the Mo2B2Fe Type as a Function of the Rare Earth Size." Zeitschrift für Naturforschung B 68, no. 1 (2013): 10–16. http://dx.doi.org/10.5560/znb.2013-2296.

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The stannides RE2Ni2Sn (RE=Pr, Ho, Er, Tm) were synthesized by arc-melting of the elements and characterized by powder X-ray diffraction. Pr2Ni2Sn crystallizes with the orthorhombic W2B2Co-type structure, Immm, a=443.8(1), b=572.1(1), c=855.1(2) pm, wR2=0.0693, 293 F2 values, 13 variables. A structural transition to the tetragonal Mo2B2Fe type occurs for the heavier rare earth elements. The structures of Ho2Ni2Sn (a=729.26(9), c=366.66(7) pm, wR2=0.0504, 250 F2 values, 12 variables), Er2Ni2Sn (a=727.2(2), c=364.3(1) pm, wR2=0.0397, 262 F2 values, 12 variables), and Tm2Ni2Sn (a=725.2(1), c=362.

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Ilgaz, Ceren, Haşim Kelebek, and Pınar Kadiroglu. "Ultrasound-Assisted Extraction of Hydroxytyrosol from Lactiplantibacillus plantarum Fermented Olive Leaves: Process Optimization and Bioactivity Assessment." Fermentation 9, no. 6 (2023): 514. http://dx.doi.org/10.3390/fermentation9060514.

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Olive leaves are important by-products for the recovery of phenolic compounds and extracts with high phenolic content using lactic acid bacteria during fermentation. Lactiplantibacillus plantarum (L. plantarum) strains as glucosidase-positive strains are starter cultures used to control the fermentation process. The main objective of the present work is to determine the most effective strain for the biodegradation of oleuropein to hydroxytyrosol using two L. plantarum strains for the fermentation of olive leaves. Box–Behnken experimental design was applied to determine the optimum ultrasound-a

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Ho, Allen L., Eric S. Sussman, Arjun V. Pendharkar, et al. "Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy." Journal of Neurosurgery 128, no. 4 (2018): 1165–72. http://dx.doi.org/10.3171/2017.1.jns162046.

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OBJECTIVEMR-guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive method for thermal destruction of benign or malignant tissue that has been used for selective amygdalohippocampal ablation for the treatment of temporal lobe epilepsy. The authors report their initial experience adopting a real-time MRI-guided stereotactic platform that allows for completion of the entire procedure in the MRI suite.METHODSBetween October 2014 and May 2016, 17 patients with mesial temporal sclerosis were selected by a multidisciplinary epilepsy board to undergo a selective amygdalohippocampa

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Truyen, Phuoc Le, and Phung Nguyen The Nguyen. "Prognostic value of N–terminal pro B–type natriuretic peptide and troponin I in children with dengue shock syndrome." Asian Pacific Journal of Tropical Medicine 17, no. 4 (2024): 166–72. http://dx.doi.org/10.4103/apjtm.apjtm_871_23.

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Objective: To investigate the contribution of N-terminal pro B-type natriuretic peptide (NT-pro BNP) and troponin I to mortality in children with dengue shock syndrome. Methods: A longitudinal study was conducted on children with dengue shock syndrome in a hospital in southern Vietnam. Detailed clinical histories, physical examinations, and laboratory parameters, including NT-pro BNP and troponin I, were recorded. A comparison between survival and non-survival was carried out to identify factors influencing mortality. Results: A total of 107 patients with a median age of 9 years were included

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Oldham, Mark, Wilfred Pigeon, Michael Yurcheshen, and Hochang Lee. "0471 Having a Surgical Aortic Valve Replacement? You Very Likely Have Obstructive Sleep Apnea." SLEEP 46, Supplement_1 (2023): A209. http://dx.doi.org/10.1093/sleep/zsad077.0471.

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Abstract Introduction Patients with advanced aortic stenosis (AS) have a high risk of sleep-related breathing disorders (SRBD), yet prior research is limited to type III sleep apnea tests. Whereas the American Academy of Sleep Medicine recommends polysomnography for SRBD diagnosis in patients with significant cardiorespiratory disease, unattended studies are often more acceptable, especially to surgical candidates. We conducted this study to address the need for comprehensive sleep testing in patients with advanced AS. Methods We conducted unattended type II sleep tests in 23 adults aged 50 an

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Prada, Sergio Iván, José Joaquín Toro, Evelyn E. Peña-Zárate, Laura Libreros-Peña, Juliana Alarcón, and María Fernanda Escobar. "Impact of a teaching hospital-based multidisciplinary telemedicine programme in Southwestern Colombia: a cross-sectional resource analysis." BMJ Open 14, no. 5 (2024): e084447. http://dx.doi.org/10.1136/bmjopen-2024-084447.

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BackgroundTelemedicine, a method of healthcare service delivery bridging geographic distances between patients and providers, has gained prominence. This modality is particularly advantageous for outpatient consultations, addressing inherent barriers of travel time and cost.ObjectiveWe aim to describe economical outcomes towards the implementation of a multidisciplinary telemedicine service in a high-complexity hospital in Latin America, from the perspective of patients.DesignA cross-sectional study was conducted, analysing the institutional data obtained over a period of 9 months, between Apr

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Hassan, Waqed H., Suhail T. Khazaal, and Musa H. Al-Shammari. "Effect of Climate Change on Wetland Areas in West Iraq Using Satellite Data and GIS Techniques." Civil Engineering Journal 10, no. 9 (2024): 2966–78. http://dx.doi.org/10.28991/cej-2024-010-09-013.

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Iraq is considered to amongst those countries in the Middle Eastern region that are most exposed to the effects of climate change, which will have notable effects on wet areas and lakes. Natural or industrial water resources must be paid particular attention due to their importance in preserving environmental and biological systems, in addition to their economic and social importance. As a result of the effects of climatic change, water resources in Iraq have seen a multitude of changes. The aim of this study is to determine changes in the wetland area around AL-Razzaza Lake, Karbala province,

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Kovarna, Madison, Michael Gonda, Gemechis Djira, Zachary K. Smith, and Cody Wright. "PSIII-13 Effects of Weather, Body Weight, and Feed Intake on Total and Liquid Water Intake in Beef Bulls." Journal of Animal Science 101, Supplement_3 (2023): 386–87. http://dx.doi.org/10.1093/jas/skad281.458.

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Abstract Research conducted in the 1950s to determine water requirements used cattle that vary greatly from the animals being raised today. Changes in lean composition and growth rate in young cattle and milk production and mature size in cows have likely altered water requirements. Furthermore, most of the research has been conducted on animals being fed for slaughter, rather than bulls or reproductive females. The objective of this study was to analyze the effect of weather variables, dry matter intake (DMI), and body weight (BW) on total daily water intake (TDWI) in growing beef bulls. Angu

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Wisdom, Harrison Kofi Hordzi. "Effects of Megachile sp, an insect flower visitor on nutrient content of progenies of cowpea [Vigna unguiculata (L.) Walp]." International Journal of Novel Research in Life Sciences 9, no. 4 (2022): 39–49. https://doi.org/10.5281/zenodo.7007234.

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<strong>Abstract:</strong> Though cowpea (<em>Vigna unguiculata</em> (L.)Walp) possess several nutritional values its mode of pollination is fraught with some forms of confusion. Attempt to ascertain the role of insect visitors on the plant led to collection of seeds from flowers visited by bee species known as <em>Megachile</em> (experimental plants) and flowers not visited by any organism (control plants). The seeds were re-sown to determine the influence of <em>Megachile</em> on nutrient contents of the seeds of the progenies. Nutrient analysis of the seeds from the progenies was done. Mean

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Van Caam, A., J. Lemmers, M. Vonk, and S. Van Leuven. "AB0152 URIC ACID IN SYSTEMIC SCLEROSIS-RELATED PULMONARY ARTERIAL HYPERTENSION:INNOCENT BYSTANDER OR COVERT ACCOMPLICE?" Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1255.2–1256. http://dx.doi.org/10.1136/annrheumdis-2023-eular.859.

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BackgroundWhen uric acid levels increase to reach the supersaturation level (>70 μg/ml), it transforms into its crystalline form and binds to surface lipids on immune cells. Phagocytes ingest this cellular debris and thereby receive a ‘danger signal’ from uric acid and are stimulated to mature and become immunostimulatory [1,2].ObjectivesConsidering uric acid helps to predict the development of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) (3), we aim to establish whether uric acid induces a pro-inflammatory response in SSc in general and in SSc-PAH in particular.Methods

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Gao, Jing, and Liang Wang. "Efficacy and Safety of BTK Inhibitors in Vitreoretinal Lymphoma: A Single-Center, Retrospective Analysis of 24 Patients." Blood 142, Supplement 1 (2023): 3134. http://dx.doi.org/10.1182/blood-2023-180354.

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Background: Vitreoretinal lymphoma (VRL) is a special subtype of rare central nervous system lymphoma (PCNSL). Most of the pathologic types are diffuse large B-cell lymphoma of non-germinal central origin. Currently, the optimal treatment strategy for VRL is not clear, and the traditional treatment usually includes about 20 repeated intravitreal injections of low doses of methotrexate or intraocular local radiotherapy. Eventually, however, 60-90% of VRL will progress to PCNSL. Therefore, CNS prophylaxis of VRL patients is very important. A previous prospective clinical study of our research gr

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Pechetty, Priyanka, Chandrakala Shanmukhaiah, Shubhranshu Shekhar Mohanty, et al. "Perioperative Management of Hemophiliacs - a Retrospective Study from an Ihtc in a Lower Middle-Income Country." Blood 144, Supplement 1 (2024): 5486. https://doi.org/10.1182/blood-2024-211189.

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Background: The management of surgical procedures in individuals with haemophilia is a matter of considerable concern due to the potential impact on health outcomes. Inadequate haemostatic control may significantly contribute to morbidity and mortality. However, the success of surgical procedures is contingent not only upon the appropriate replacement of the deficient factor but also on pre- and post-operative interventions, laboratory monitoring, and patient care and rehabilitation. It is imperative to conduct surgical procedures for patients with haemophilia in fully equipped hospitals capab

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Vichinsky, Elliott P., Janet Kwiatkowski, Patricia J. Giardina, et al. "Epidemiologic and Clinical Characteristics of Thalassemia (Thal) Intermedia (TI) in the United States." Blood 126, no. 23 (2015): 3279. http://dx.doi.org/10.1182/blood.v126.23.3279.3279.

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Abstract Introduction TI is increasingly prevalent in the US due to changing immigration patterns. It is underdiagnosed, leading to inadequate or delayed management. This study reviewed the prevalence, epidemiology, and clinical characteristics of TI in patients (pts) in the US. Methods Medical records from 1/1997- 4/2014 at 4 US hematology centers were reviewed. Index date was the 1st TI visit at a center on or after 1/1/1997. Eligible pts had a TI diagnosis (≤8 mean packed red blood cell transfusions per year (yr) over a ≥3-y period after index date) and ≥12 months of follow-up. Data spanned

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Scheinberg, Phillip, Diego Villa Cle, Berangere Devalet, et al. "Phase III Randomized COMMODORE 1 Trial: 2-Year Safety and Efficacy of Crovalimab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Switched from Eculizumab." Blood 144, Supplement 1 (2024): 1313. https://doi.org/10.1182/blood-2024-200745.

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Introduction Crovalimab (crova; PiaSky®) is a novel C5 inhibitor (C5i) allowing for maintenance subcutaneous (SC) injection every 4 wks (Q4W). Results from the 24-wk primary treatment period of the global, randomized, Phase III COMMODORE 1 trial (NCT04432584) showed that crova was well tolerated and had similar efficacy in patients (pts) who switched from eculizumab (ecu) to crova vs pts who continued ecu (Scheinberg Am J Hematol 2024). These data, in conjunction with the COMMODORE 2 trial (NCT04434092) that demonstrated non-inferior efficacy of crova vs ecu in C5i-naive pts (Röth Am J Hematol

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Röth, Alexander, Guangsheng He, Andres Brodsky, et al. "Phase III Randomized COMMODORE 2 Trial: 2-Year Efficacy and Safety of Crovalimab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Naive to Complement Inhibition." Blood 144, Supplement 1 (2024): 2687. https://doi.org/10.1182/blood-2024-208072.

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Introduction Crovalimab (crova; PiaSky®) is a novel C5 inhibitor (C5i) allowing for maintenance subcutaneous (SC) injection every 4 wks (Q4W). Results from the 24-wk primary treatment period of the global, randomized, Phase III COMMODORE 2 (NCT04434092) trial demonstrated the non-inferior efficacy and comparable safety of crova vs eculizumab (ecu) in C5i-naive patients (pts) with PNH (Röth Am J Hematol 2024). These data were supported by the COMMODORE 1 (NCT04432584) trial in C5i-experienced pts (Scheinberg Am J Hematol 2024). Here, we report long-term data from COMMODORE 2, with up to 2 y of

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Fernandes, Renato, Rafael Oliveira, Alexandre D. Martins, and João Moreira de Brito. "Internal training and match load quantification of one-match week schedules in female first league Portugal soccer team." Cuadernos de Psicología del Deporte 21, no. 3 (2021): 126–38. http://dx.doi.org/10.6018/cpd.469141.

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La cuantificación de la carga de entrenamiento (TL) permite a los entrenadores gestionar la carga durante el entrenamiento con el objetivo de estar en la mejor forma física para la próxima competición. El propósito de este estudio fue comparar la Percepción Subjetiva de Esfuerzo (s-RPE) y el Índice Hooper (HI) entre deportes y partidos de un solo equipo de fútbol de la principal liga femenina portuguesa. En este estudio participaron dieciséis jugadores con una media ± DE edad, altura y peso de 24,0 ± 2,9 años, 164 ± 4,1 cm y 58,5 ± 8,2 kg, respectivamente. Los participantes completaron ≥80% de

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Erb, Carl, Sophie Eckert, Pia Gindorf, et al. "Electrical neurostimulation in glaucoma with progressive vision loss." Bioelectronic Medicine 8, no. 1 (2022). http://dx.doi.org/10.1186/s42234-022-00089-9.

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Abstract Background The retrospective study provides real-world evidence for long-term clinical efficacy of electrical optic nerve stimulation (ONS) in glaucoma with progressive vision loss. Methods Seventy glaucoma patients (45 to 86 y) with progressive vision loss despite therapeutic reduction of intraocular pressure (IOP) underwent electrical ONS. Closed eyes were separately stimulated by bipolar rectangular pulses with stimulus intensities up to 1.2 mA sufficient to provoke phosphenes. Ten daily stimulation sessions within 2 weeks lasted about 80 min each. Right before ONS at baseline (PRE

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Jones, Sydney, Rebecca F. Gottesman, Eyal Shahar, Lisa Wruck, and Wayne D. Rosamond. "Abstract MP90: Validity of Hospital Discharge Diagnosis Codes for Stroke: Evaluation of New American Heart Association/American Stroke Association Definitions." Circulation 129, suppl_1 (2014). http://dx.doi.org/10.1161/circ.129.suppl_1.mp90.

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Background: Characterizing International Classification of Disease (ICD-9) code validity is essential given widespread use of hospital discharge and claims databases in research. Estimates for acute stroke vary depending on the codes investigated. We sought to estimate the validity of ICD-9 codes grouped according to the 2013 American Heart Association/ American Stroke Association (AHA/ASA) updated stoke definition and to explore differences by patient characteristics and study site. Methods: Medical records (N=4,260) containing ICD-9 codes 430-438 or stroke keywords in the discharge summary w

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Kuang, Penghao, Yuanyuan Wang, Guoyang Wu, et al. "Endoscopic lateral neck dissection via the breast and transoral approaches for papillary thyroid carcinoma: A preliminary report." Frontiers in Surgery 9 (November 1, 2022). http://dx.doi.org/10.3389/fsurg.2022.997819.

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PurposeComplete lymph node dissection is essential for the management of papillary thyroid carcinoma (PTC) with lymph node metastasis (LNM). This work aimed to describe the feasibility of endoscopic lateral neck dissection via the breast and transoral approach (ELNDBTOA) in PTC patients and the necessity of the addition of the transoral approach.MethodsWe included 13 patients with PTC and suspected lateral LNM who underwent ELNDBTOA at the Zhongshan Hospital, Xiamen University. Total thyroidectomy, ipsilateral central lymph node dissection, and selective neck dissection (levels IIA, IIB, III,

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Buhl, Lara, Stephan Thurau, and Christoph Kern. "Fluocinolone acetonide 0.19-mg implant for the treatment of noninfectious uveitis with involvement of the posterior segment: a real-world study." Graefe's Archive for Clinical and Experimental Ophthalmology, November 18, 2022. http://dx.doi.org/10.1007/s00417-022-05893-2.

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Abstract Purpose To evaluate the effectiveness of 0.19-mg fluocinolone acetonide implant (FAi) for preventing inflammatory relapses in noninfectious uveitis with posterior segment involvement in standard clinical practice. Further, to assess the value of remission induction therapy with intraocular and periorbital administered high-dose corticosteroids before FAi. Methods A retrospective cohort study in a tertiary referral center specialized in uveitis management. The primary study outcomes were the best-corrected visual acuity (BVCA) and central retinal thickness (CRT) within a 12-month obser

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Comins, Meg M., Dawood H. Sultan, and Deanna J. Wathington. "Abstract P31: Medicare Reimbursement and Patterns of tPA Utilization for Acute Ischemic Stroke Patients." Circulation: Cardiovascular Quality and Outcomes 4, suppl_1 (2011). http://dx.doi.org/10.1161/circoutcomes.4.suppl_1.ap31.

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Background. Tissue plasminogen activator (tPA) is recommended for stroke patients presenting within 3 hours of symptom onset. Patients treated with tPA have been shown to experience superior outcomes over other thrombolytics. Higher costs for tPA are said to be offset by savings from shorter lengths of stay and lower likelihoods of being discharged to rehabilitation or long-term care. Encouraged by the American Stroke Association (ASA), CMS created DRG 559 in FY 2006, increasing the reimbursement for stroke patients receiving tPA by an average of $6,700 to advance tPA utilization. In FY 2007,

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Jiang, Haihui, Kefu Yu, Yong Cui, et al. "Combination of Immunotherapy and Radiotherapy for Recurrent Malignant Gliomas: Results From a Prospective Study." Frontiers in Immunology 12 (May 7, 2021). http://dx.doi.org/10.3389/fimmu.2021.632547.

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BackgroundWorld Health Organization (WHO) grade IV glioma remains one of the most lethal tumors with a dismal prognosis and inevitable recurrence. We evaluated the safety and efficacy of immunotherapy with radiotherapy in this population of patients.MethodsThis study was a single-arm, open-label, phase I trial based on patients with recurrent WHO grade IV glioma. Patients were treated with intracranial and systemic immunoadjuvants in combination with low-dose reirradiation. The primary endpoint of the present trial was safety. Secondary endpoints were overall survival (OS) and progression-free

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Zhang, Li, Delin Li, Yongsheng Zhang, et al. "Changes in the gut microbiota of esophageal carcinoma patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis." Frontiers in Oncology 14 (August 29, 2024). http://dx.doi.org/10.3389/fonc.2024.1366975.

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BackgroundThis study conducts a systematic review through meta-analysis, comparing the composition and diversity of the gut microbiome in patients with esophageal cancer and healthy individuals, and explores the relationship between risk factors and related factors of esophageal cancer.MethodsAccording to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), we comprehensively searched the databases of PubMed, Web of Science, Embase, Cochrane Library. In addition, we applied the R programming language version 4.0.3 and Stata 15.1 software for data analysis. We also i

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Tschaidse, L., H. F. Nowotny, M. Auer, et al. "8665 Female Fertility In Patients With Classic And Non-Classic Congenital Adrenal Hyperplasia Under Modified-Release Hydrocortisone (MR-HC)." Journal of the Endocrine Society 8, Supplement_1 (2024). http://dx.doi.org/10.1210/jendso/bvae163.189.

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Abstract Disclosure: L. Tschaidse: None. H.F. Nowotny: None. M. Auer: None. C. Lottspeich: None. M. Bidlingmaier: None. J. Hawley: None. B.G. Keevil: None. N. Reisch: None. Background: Female patients with classic and non-classic (NC) CAH struggle with fertility, due to androgen excess, elevated progesterone and 17-hydroxyprogesterone (17OHP) levels, causing anovulation, impairment of endometrial development and menstrual irregularities. The typical approach to treating infertility often includes an increase in glucocorticoid (GC) dose. However, this poses a potential risk of side effects. Lim

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Liu, Zuokun, Yixin Li, Zhuo Li, Jingya Dong, Huan Yu, and Hui Yin. "Assessing self-reported public health emergency competencies for civil aviation personnel in China: a pilot study." BMC Public Health 24, no. 1 (2024). http://dx.doi.org/10.1186/s12889-024-18846-7.

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Abstract Introduction COVID-19 has demonstrated the importance of competent staff with expertise in public health emergency preparedness and response in the civil aviation system. The civil aviation system is a critical sentinel and checkpoint to prevent imported cases and slow the spread of communicable diseases. Understanding the current competencies of staff to deal with public health emergencies will help government agencies develop targeted training and evidence-based policies to improve their public health preparedness and response capabilities. Methods This cross-sectional pilot study w

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Hwang, M., R. Shamburek, M. Lightbourne, et al. "5123 Remission of Antibodies Blocking the Insulin Receptor Reduces Atherogenicity of LDL Particles but Increases HDL Particle Atherogenicity." Journal of the Endocrine Society 8, Supplement_1 (2024). http://dx.doi.org/10.1210/jendso/bvae163.605.

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Abstract Disclosure: M. Hwang: None. R. Shamburek: None. M. Lightbourne: None. M. Sampson: None. A. Remaley: None. B. Abel: None. R.J. Brown: None. Background: Type B insulin resistance syndrome (TBIR) is a rare autoimmune disorder defined by the presence of autoantibodies against the insulin receptor, usually in the context of systemic autoimmune diseases such as lupus. In TBIR, insulin signaling is disrupted at the receptor-level, resulting in failure of insulin to both suppress hepatic glucose production and to stimulate de novo lipogenesis. This leads to a phenotype of extreme insulin resi

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