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1

Carter, Warren. "Matthew 23:37–39." Interpretation: A Journal of Bible and Theology 54, no. 1 (January 2000): 66–68. http://dx.doi.org/10.1177/002096430005400110.

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2

Reid, Barbara E. "John 7:37–39." Interpretation: A Journal of Bible and Theology 63, no. 4 (October 2009): 394–96. http://dx.doi.org/10.1177/002096430906300406.

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3

Segerman, Henry, and Paul-Olivier Dehaye. "Solutions to autologlyphs (pp. 37–39)." Mathematical Intelligencer 26, no. 2 (March 2004): 44. http://dx.doi.org/10.1007/bf02985652.

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4

O’Bryhim, Shawn. "Egnatius asDux Gregis(Catullus 37 and 39)." Classical Philology 113, no. 3 (July 2018): 352–60. http://dx.doi.org/10.1086/698017.

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5

Behrends, Heinz. "Exaudi – 28. 5. 2017 Johannes 7, 37–39." Homiletische Monatshefte 92, no. 7 (March 16, 2017): 386–90. http://dx.doi.org/10.13109/homh.2016.92.7.386.

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6

Sezik, Mekin. "Early term labors: approach principles at 37-39 weeks of gestation." Perinatal Journal 22, no. 3 (December 1, 2014): 167–73. http://dx.doi.org/10.2399/prn.14.0223004.

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7

Blevins, Carolyn. "Under My Wings: Jesus' Motherly Love: Matthew 23:37–39." Review & Expositor 104, no. 2 (May 2007): 365–74. http://dx.doi.org/10.1177/003463730710400209.

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8

Zijlstra, Gea. "(37‐39) Three proposals to reduce the need to conserve names." TAXON 47, no. 2 (May 1998): 487–88. http://dx.doi.org/10.2307/1223798.

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9

Aumard, Sylvain. "Saint-Benoît-sur-Loire (Loiret). Maison romane, 37-39 rue Orléanaise." Archéologie médiévale, no. 49 (December 20, 2019): 242–43. http://dx.doi.org/10.4000/archeomed.25031.

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10

Loosli, H. H., B. E. Lehmann, and W. Balderer. "Argon-39, argon-37 and krypton-85 isotopes in Stripa groundwaters." Geochimica et Cosmochimica Acta 53, no. 8 (August 1989): 1825–29. http://dx.doi.org/10.1016/0016-7037(89)90303-7.

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11

Kunz, Ralph. "Hebr 10,35-36(37-38)39 5.10.2014 16. Sonntag nach Trinitatis." Göttinger Predigtmeditationen 68, no. 4 (July 2013): 446–51. http://dx.doi.org/10.13109/gpre.2013.68.4.446.

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Kunz, Ralph. "Hebr 10,35-36(37-38)39 5.10.2014 16. Sonntag nach Trinitatis." Pastoraltheologie 103, no. 8 (July 2014): 446–51. http://dx.doi.org/10.13109/path.2014.103.8.446.

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13

Huddlestun, John R. "Divestiture, Deception, and Demotion: The Garment Motif in Genesis 37–39." Journal for the Study of the Old Testament 26, no. 4 (June 2002): 47–62. http://dx.doi.org/10.1177/030908920202600403.

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14

Augusto, Pedro ED. "Editorial overview: Food physics & materials science Vol. 37–39 — 2021." Current Opinion in Food Science 38 (April 2021): iii—iv. http://dx.doi.org/10.1016/j.cofs.2021.03.003.

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15

Bienaimé, Germain. "L'annonce des fleuves d'eau vive en Jean 7, 37-39 (Première partie)." Revue théologique de Louvain 21, no. 3 (1990): 281–310. http://dx.doi.org/10.3406/thlou.1990.2448.

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16

Karrer, Martin. "Hebräer 10, 35–36 (37–38) 39 7.9.2008 16. Sonntag nach Trinitatis." Göttinger Predigtmeditationen 62, no. 4 (July 2007): 393–99. http://dx.doi.org/10.13109/gpre.2007.62.4.393.

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17

Krostenko, Brian A. "Arbitria Vrbanitatis: Language, Style, and Characterization in Catullus cc. 39 and 37." Classical Antiquity 20, no. 2 (October 1, 2001): 239–72. http://dx.doi.org/10.1525/ca.2001.20.2.239.

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This article describes how cc. 39 and 37 create distinct tones of voice and use them to preclude the social pretensions of Egnatius in different spheres. The style of c. 39, markedly oratorical——and non-Catullan——in the syntax of its opening lines, develops into the voice of a respectable senex by way of archaisms of vocabulary and syntax and is capped by a figure of humor otherwise absent from the polymetrics, the apologus. The style thus creates a voice perfectly suited to chastise Egnatius' social ineptitudes and, more importantly, constitutes on the verbal level an embodiment of the standards of the urban elite. Catullus thus illustrates to Egnatius that a subtle system of social gestures can be learned - something which Egnatius, for all his apparent pretensions to social prominence, manifestly has not grasped, marred as he is by the habit of grinning inappropriately. C. 37, which ends with an attack on the same Egnatius, is far different in tone, commingling tokens of artfulness with vulgarity and forcefulness. That mixed style exercises ironic decorum towards Lesbia's lovers, who are themselves an oddly mixed group, well-off on the one hand, but "backstreet adulterers" on the other. But the two tones of voice, and indeed the two groups of lovers, also embody the paradoxes of the Roman construction of stylish behavior, which could be represented as elegant dalliance or reprehensible vice. Inasmuch as Egnatius' fashion affectations, ridiculed at the poem's end, fail to qualify him for the ranks of Lesbia's lovers, he is represented as outside sophisticated society, however it be constructed. In concert the two poems utterly derail Egnatius' social pretensions: c. 39 as it were outflanks him on the "right," barring him from respectable society, and c. 37 outflanks him on the "left," barring him from the "jet set."
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18

史, 应光. "Turán问题37—39的完全解." Science in China Series A-Mathematics, Physics, Astronomy & Technological Science (in Chinese) 23, no. 5 (May 1, 1993): 461–70. http://dx.doi.org/10.1360/za1993-23-5-461.

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19

Bienaimé, Germain. "L'annonce des fleuves d'eau vive en Jean 7, 37-39 (suite et fin)." Revue théologique de Louvain 21, no. 4 (1990): 417–54. http://dx.doi.org/10.3406/thlou.1990.2465.

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20

Riedmann, Robin A., and Roland Purtschert. "Separation of argon from environmental samples for Ar-37 and Ar-39 analyses." Separation and Purification Technology 170 (October 2016): 217–23. http://dx.doi.org/10.1016/j.seppur.2016.06.017.

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21

Bowers, Katherine, Jane Khoury, and Tetsuya Kawakita. "Nonmedically Indicated Induction of Labor Compared with Expectant Management in Nulliparous Women Aged 35 Years or Older." American Journal of Perinatology 36, no. 01 (May 3, 2018): 045–52. http://dx.doi.org/10.1055/s-0038-1648228.

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Objective This article compares maternal and neonatal outcomes in women aged ≥ 35 years who experienced nonmedically indicated induction of labor (NMII) versus expectant management. Study Design This was a retrospective cohort study of nulliparas aged ≥ 35 years with a singleton and cephalic presentation who delivered at term. Outcomes were compared between women who underwent NMII at 37, 38, 39, and 40 weeks' gestation and those with expectant management that week. Adjusted odds ratios (aORs) with 95% confidence intervals (95% CIs) were calculated, controlling for predefined covariates. Results Of 3,819 nulliparas aged ≥ 35 years, 1,409 (36.9%) women underwent NMII. Overall at 39 weeks' gestation or later, maternal and neonatal outcomes were similar or improved with NMII. At 37, 38, and 39 weeks' gestation, NMII compared with expectant management was associated with decreased odds of cesarean delivery at 37, 38, and 39 weeks' gestation. At 40 weeks' gestation, NMII compared with expectant management was associated with an increased odds of operative vaginal delivery and a decreased odds of neonatal intensive care unit (NICU) admission. Conclusion In nulliparous women aged ≥ 35 years, NMII was associated with decreased odds of cesarean delivery at 37 to 39 weeks' gestation and decreased odds of NICU admission at 40 weeks' gestation compared with expectant management.
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22

Bernabucci, Umberto, Loredana Basiricò, Patrizia Morera, Nicola Lacetera, Bruno Ronchi, and Alessandro Nardone. "Heat shock modulates adipokines expression in 3T3-L1 adipocytes." Journal of Molecular Endocrinology 42, no. 2 (November 7, 2008): 139–47. http://dx.doi.org/10.1677/jme-08-0068.

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Studies have demonstrated that heat shock is associated with alteration in energy metabolism. In this study, we investigated the effect of heat shock on gene expression and secretion of adiponectin and leptin, and gene expression of Hspa2 and Pparγ in 3T3-L1 adipocytes. Compared with 37 °C, adiponectin mRNA was higher at 39 °C, and lower at 41 °C. Leptin mRNA was higher when adipocytes were exposed to 41 °C compared with 37 and 39 °C. Secretion of adiponectin increased at 39 °C, and when cells were exposed to 41 °C it was not detectable. Leptin secretion increased significantly at 41 °C, compared with 37 and 39 °C. Hspa2 mRNA was increased at 39 °C, and the highest level was reached at 41 °C. Pparγ mRNA exhibited a substantial increase in a temperature-dependent manner. The study provides the first evidence of a possible direct effect of heat shock on adiponectin and leptin gene expression and secretion, and demonstrates that the expression of the two adipokines is differentially regulated at the temperatures tested.
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23

Flores Méndez, J., A. C. Piñón Reyes, M. Moreno Moreno, A. Morales-Sánchez, Gustavo M. Minquiz, R. C. Ambrosio Lázaro, H. Vázquez Leal, and F. Candia García. "Erratum: Flores, J., et al. Effective Parameters for 1D Photonic Crystals with Isotropic and Anisotropic Magnetic Inclusions: Coherent Wave Homogenization Theory. Materials 2020, 13, 1475." Materials 13, no. 14 (July 8, 2020): 3053. http://dx.doi.org/10.3390/ma13143053.

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The authors wish to make the following corrections to this paper [1]: replace: (37) 1 ε z = f ε m = 1 − f ε d and (39) 1 μ z = f μ m = 1 − f μ d with the correct expressions: (37) 1 ε z = f ε m + 1 − f ε d and (39) 1 μ z = f μ m + 1 − f μ d [...]
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24

Lucas, Anne D., Sharon K. Lappalainen, and Diane Wray-Cahen. "Hyperthermia Increases the Cytotoxicity of Many Exogenous Compounds." Biomedical Instrumentation & Technology 43, no. 1 (January 1, 2009): 73–79. http://dx.doi.org/10.2345/0899-8205-43.1.73.

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Abstract Cytotoxicity testing of extracts from medical device materials is typically conducted at 37°C. It may be more relevant to screen extracts from device materials for in vitro cytotoxicity at temperatures found in febrile patients. To address this, the cytotoxicity of selected chemicals, drugs, and medical device extracts was evaluated in vitro following incubation at normothermic (37°C) and hyperthermic (39°C) conditions. In L929 cells, the percentage of cell death increased from 2-fold to more than 4-fold after chemical exposure when cells were maintained at 39°C. Extracts of some medical devices and materials showed a 10-fold increase in cytotoxicity when cells were maintained at 39°C as compared to 37°C. For many of the substances in this study, exogenous compounds that are toxic at normothermic conditions (37°C) are more cytotoxic under hyperthermic conditions (39°C). The toxicity of compounds was more readily discernable at the higher incubation temperature, even at lower concentrations. In vitro cytotoxicity testing of chemicals and extracts at febrile temperatures can provide more sensitive and relevant biocompatibility tests than under normothermic conditions alone.
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25

Ives, Stephen J., Robert H. I. Andtbacka, Sun Hyung Kwon, Yan-Ting Shiu, Ting Ruan, R. Dirk Noyes, Quan-Jiang Zhang, J. David Symons, and Russell S. Richardson. "Heat and α1-adrenergic responsiveness in human skeletal muscle feed arteries: the role of nitric oxide." Journal of Applied Physiology 113, no. 11 (December 1, 2012): 1690–98. http://dx.doi.org/10.1152/japplphysiol.00955.2012.

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Increased local temperature exerts a sympatholytic effect on human skeletal muscle feed arteries. We hypothesized that this attenuated α1-adrenergic receptor responsiveness may be due to a temperature-induced increase in nitric oxide (NO) bioavailability, thereby reducing the impact of the α1-adrenergic receptor agonist phenylephrine (PE). Thirteen human skeletal muscle feed arteries were harvested, and wire myography was used to generate PE concentration-response curves at 37°C and 39°C, with and without the NO synthase (NOS) inhibitor NG-monomethyl-l-arginine (l-NMMA). A subset of arteries ( n = 4) were exposed to 37°C or 39°C, and the protein content of endothelial NOS (eNOS) and α1-adrenergic receptors was determined by Western blot analysis. Additionally, cultured bovine endothelial cells were exposed to static or shear stress conditions at 37°C and 39°C and assayed for eNOS activation (phosphorylation at Ser1177), eNOS expression, and NO metabolites [nitrate + nitrite (NOx)]. Maximal PE-induced vasocontraction (PEmax) was lower at 39°C than at 37°C [39 ± 10 vs. 84 ± 30% maximal response to 100 mM KCl (KClmax)]. NO blockade restored vasocontraction at 39°C to that achieved at 37°C (80 ± 26% KClmax). Western blot analysis of the feed arteries revealed that heating increased eNOS protein, but not α1-adrenergic receptors. Heating of bovine endothelial cells resulted in greater shear stress-induced eNOS activation and NOx production. Together, these data reveal for the first time that, in human skeletal muscle feed arteries, NO blockade can restore the heat-attenuated α1-adrenergic receptor-mediated vasocontraction and implicate endothelium-derived NO bioavailability as a major contributor to heat-induced sympatholysis. Consequently, these findings highlight the important role of vasodilators in modulating the vascular response to vasoconstrictors.
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26

Palasz, A. T., P. Beltrán Breña, M. A. Ramírez, S. Pérez-Garnelo, A. Gutiérrez-Adán, and J. De la Fuente. "146 THE EFFECT OF CULTURE TEMPERATURE ON THE CLEAVAGE, DEVELOPMENT, AND GENE TRANSCRIPTION PATTERNS OF BOVINE EMBRYOS." Reproduction, Fertility and Development 17, no. 2 (2005): 223. http://dx.doi.org/10.1071/rdv17n2ab146.

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Bovine oocytes matured and fertilized at 39°C had significantly higher rates of fertilization than at 37°C (Lenz et al. 1983 Biol. Reprod. 29, 173–179). However, embryo culture temperature that may affect molecular composition and metabolism of embryo membranes was not investigated. The objective of this study was to determine the effect of two culture temperatures, 37 and 39°C on the cleavage, in vitro development, and gene transcription patterns in bovine embryos. A total of 794 oocytes (5 replicates) were matured in TCM-199 medium containing 10% FCS and 10 ng/mL epidermal growth factor and inseminated with 1 × 106/mL spermatozoa in groups of 50 in 250 μL in Fert-Talp supplemented with 25 mM bicarbonate, 22 mM sodium lactate, 1 mM sodium pyruvate, 6 mg/mL BSA-FAF, and 10 μg/mL heparin at 39°C. After 24 h of oocyte-sperm co-incubation, presumptive zygotes were divided into two groups and cultured at 37 or 39°C under paraffin oil and 5% CO2 in humidified air. Embryos were cultured in SOFaa medium supplemented with 4% BSA in 50-μL drops (25 zygotes per drop). Cleavage rates were recorded on Day 2 and zygote development on Days 4, 7, 8, and 9. At least 5 blastocysts from each replicate from each treatment were frozen for evaluation of gene expression patterns. Poly(A) mRNA was prepared from 6 groups of pools of 5–7 embryos. A total of 11 developmentally important mRNA transcripts were examined. The quantification of all gene transcripts was performed by real time quantitative RT-PCR in three replicates. Embryo development was analyzed by chi-square analysis and data on mRNA expression by one-way repeated-measures ANOVA. There was no effect of culture temperature on embryo cleavage (65.2 and 72.0% for 37 or 39°C, respectively) but at Day 4 significantly (P < 0.05) more embryos developed to <8 cells at 39°C (32.5%) than at 37°C (25.9%). There was no difference in the total number of blastocysts produced in either temperature (22.4% at 37°C and 22.1% at 39°C), and significantly (P < 0.05) more zygotes that were at <8-cell stage at Day 4 progressed to the blastocyst stage at 37°C (86.4%) than at 39°C (66.6%). Transcript levels for genes related to response to stress (SOX, IFNτ) and glucose metabolism (Glut-1, G6pd) were higher (P < 0.05) in the blastocysts cultured at 39°C, and levels of Glut-5 (glucose metabolism) and Oct-4 (factor related to pluripotency) were higher (P < 0.05) in the blastocysts cultured at 37°C. No difference was found in mRNA transcription of genes related to apoptosis (BAX), response to heat (Hsp70), compaction (Ecad, Na/K, DcII), and cell connection (Cx43) at either temperature tested. It can be concluded that culture temperature may affect embryo molecular composition and the kinetics of embryo development.
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27

Ye, Z., C. Wang, A. Kijlstra, X. Zhou, and P. Yang. "A Possible Role for Interleukin 37 in the Pathogenesis of Behcet's Disease." Current Molecular Medicine 14, no. 4 (May 31, 2014): 535–42. http://dx.doi.org/10.2174/1566524014666140414210831.

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28

Kaneider, Nicole C., Angela Djanani, and Christian J. Wiedermann. "Heparan Sulfate Proteoglycan–Involving Immunomodulation by Cathelicidin Antimicrobial Peptides LL-37 and PR-39." Scientific World JOURNAL 7 (2007): 1832–38. http://dx.doi.org/10.1100/tsw.2007.285.

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29

DUVAL, Yvette. "Celerinus et les siens d'après la correspondance de Cyprien (Ep. 21-23, 37, 39)." Revue d'Etudes Augustiniennes et Patristiques 47, no. 1 (January 2001): 33–62. http://dx.doi.org/10.1484/j.rea.5.104830.

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30

Hu, Song, Fei Wang, and Hua Wang. "A 28-/37-/39-GHz Linear Doherty Power Amplifier in Silicon for 5G Applications." IEEE Journal of Solid-State Circuits 54, no. 6 (June 2019): 1586–99. http://dx.doi.org/10.1109/jssc.2019.2902307.

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31

Gwazdauskas, F. C., C. McCaffrey, T. G. McEvoy, and J. M. Sreenan. "In vitro preimplantation mouse embryo development with incubation temperatures of 37 and 39�C." Journal of Assisted Reproduction and Genetics 9, no. 2 (April 1992): 149–54. http://dx.doi.org/10.1007/bf01203755.

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32

Muazzam, MG. "An Unusual Case: Intestinal Polyposis Coli." Bangladesh Journal of Medical Science 1, no. 4 (July 2, 2013): 37–39. http://dx.doi.org/10.3329/bjms.v1i4.15548.

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33

Hasina, Kaniz. "Pediatric Surgical Oncology in Bangladesh: Incidence and Prevalence (Global & Bangladesh)." Journal of Paediatric Surgeons of Bangladesh 5, no. 2 (May 14, 2016): 37–39. http://dx.doi.org/10.3329/jpsb.v5i2.27721.

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34

Azad, Abul Kalam. "Initiatives and Pitfalls in Medical Care and Education in a Digital Age." Bangladesh Journal of Medical Biochemistry 6, no. 2 (January 13, 2014): 37–39. http://dx.doi.org/10.3329/bjmb.v6i2.17641.

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35

Price, J. M., and F. R. Wilmoth. "Elevated body temperature and increased blood vessel sensitivity in spontaneously hypertensive rats." American Journal of Physiology-Heart and Circulatory Physiology 258, no. 4 (April 1, 1990): H946—H953. http://dx.doi.org/10.1152/ajpheart.1990.258.4.h946.

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Body temperature (BT) was significantly greater in spontaneously hypertensive rats (SHR) than in Wistar-Kyoto (WKY) rats regardless of the time of day, length of rectal probe, sex, age, or commercial vendor. Bath temperature (theta) for excised aortic rings was controlled by a thermoelectric Peltier module with an accuracy of 0.1 degree C. At peak force in individual contractions of norepinephrine (NE) dose-response experiments, theta was changed from 37 to 39 degrees C. Active and resting wall tension (Tw) were increased, and the mean effective dose (ED50) was decreased in the SHR aorta with and without endothelium. For the WKY aorta, active and resting Tw were increased, but ED50 was the same with and without endothelium. These results were supported by experiments where theta was decreased from 39 to 37 degrees C and by experiments on Sprague-Dawley rats. Potassium dose-response experiments with aorta from SHR and WKY rats show an increase in sensitivity at 39 degrees C, but active Tw is the same at 39 and 37 degrees C. When compared at the BT of each rat, the NE ED50 was lower and resting Tw was higher in the SHR aorta than in the WKY aorta, but active Tw was the same.(ABSTRACT TRUNCATED AT 250 WORDS)
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36

Nielsen, Chloe, Kelly Zafman, Nathan Fox, and Emily Miller. "Optimal Timing of Delivery in Women with Higher Order Cesareans: A Cohort Study." American Journal of Perinatology 35, no. 12 (April 16, 2018): 1154–58. http://dx.doi.org/10.1055/s-0038-1641587.

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Objective To evaluate whether a planned early term delivery or a planned 39-week delivery is associated with differences in perinatal outcomes in women undergoing a higher order cesarean (HOC). Study Design This cohort study included women with singleton gestations with a history of three or more prior cesareans who delivered at one of two urban tertiary care hospitals. One center routinely delivered HOC at 39 weeks' gestation and the other at 37 weeks. Maternal and neonatal morbidities were compared using bivariable and multivariable analyses. Results The policy of 37-week delivery was associated with a decrease in unscheduled deliveries (15.3 vs. 41.1%; p < 0.001). Planned delivery at 37 weeks was associated with a decreased incidence of composite maternal morbidity (1.6 vs. 7.9%; p = 0.002) and 5-minute Apgar score less than 7 (0.4 vs. 6.4%; p < 0.001), but these differences were not significant after controlling for potential confounders (adjusted odds ratio [aOR]: 0.30, 95% confidence interval [CI]: 0.08–1.17; aOR: 0.13, 95% CI: 0.01–1.30, respectively). There were no other differences in perinatal outcomes. Conclusion Compared with planned delivery at 39 weeks, a policy of planned delivery at 37 weeks was associated with a reduction in unscheduled deliveries, but there were no measured differences in perinatal outcomes.
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37

Zeng, Rong, Min Li, Qing Chen, Le Wang, Ping Zhan, Chong Wang, Guixia Lv, Yongnian Shen, and Weida Liu. "In VitroAnalyses of Mild Heat Stress in Combination with Antifungal Agents against Aspergillus fumigatus Biofilm." Antimicrobial Agents and Chemotherapy 58, no. 3 (December 16, 2013): 1443–50. http://dx.doi.org/10.1128/aac.01007-13.

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ABSTRACTAspergillus fumigatusbiofilms still present a challenge for effective treatment in clinical settings. While mild heat stress has been introduced as a treatment for infectious diseases, the effectiveness of mild heat stress onA. fumigatusbiofilm formation and antifungal susceptibility is still unknown. In the present study, confocal laser scanning microscopy (CLSM) was used to image and quantifyAspergillus fumigatusbiofilm formation under three different regimens of continuous mild heat stress: at 37, 39, and 41°C. Furthermore, fungal growth has been investigated under the above conditions in combination with antifungal drugs (amphotericin B [AMB], micafungin [MCF], and voriconazole [VOC]) at early and late stages. CLSM analysis showed that higher temperatures induce earlier germination and greater hyphal elongation but poorer polar growth and reduced biofilm thickness. In the early stage of biofilm formation, the combination of treatment at 39 or 41°C with MCF or VOC produced no visible difference in biomass formation from similar treatments at 37°C with the same drug. Interestingly, AMB treatment at 37°C inhibited early stage biofilm formation to a much greater extent than at 39 and 41°C. At the late stage of biofilm formation, the mild heat treatments at 39 and 41°C with AMB, MCF, and VOC inhibited biomass formation compared to that at 37°C. The present data show that mild heat stress has a negative regulatory effect on biofilm formationin vitro, and antifungal drug improvement with mild heat treatment at late-stage biofilm formation provides useful indications of possible effective strategies for clinical management of aspergillosis.
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38

Fedotova, Olga Andreevna, Elizaveta Alekseevna Polyakova, and Olga Ivanovna Grabelnykh. "INFLUENCE OF HIGH TEMPERATURES ON HEAT TOLERANCE AND SYNTHESIS OF HEAT SHOCK PROTEINS IN SPRING WHEAT AT THE INITIAL STAGES OF DEVELOPMENT." Siberian Journal of Life Sciences and Agriculture 12, no. 5 (December 27, 2020): 179. http://dx.doi.org/10.12731/2658-6649-2020-12-5-179-191.

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Пшеница одна из сельскохозяйственных культур, которая подвергается действию температурного стресса в течение онтогенеза и особенно чувствительна к действию стресса на начальных стадиях её развития. Высокие температуры ограничивают рост, развитие и продуктивность растений. Однако, растения могут адаптироваться к температурному стрессу и имеют адаптивные механизмы на клеточном и молекулярном уровнях. Одним из таких адаптивных механизмов является увеличение синтеза белков теплового шока (БТШ), функции которых очень важны и разнообразны.Целью данной работы было изучить влияние различных тепловых обработок (37 и 39 ºC в течение 1, 3, 6, 24 ч и 50 ºC в течение 1, 3, 5 ч) на теплоустойчивость проростков яровой пшеницы (Triticum aestivum L.) и синтез БТШ (101, 70, 60 и 16.9 кДа) в побегах 4-х суточных и листьях 8-ми суточных проростков.На основании полученных данных сделан вывод, что 4-х суточные и 8-ми суточные проростки яровой пшеницы характеризуются схожей реакцией на тепловой стресс при 50 ºC, однако 4-х суточные проростки более устойчивы в начальный период стрессового воздействия. Воздействие температурами 37 и 39 ºC подходят для адаптации яровой пшеницы на начальных стадиях её развития (4-х суточные и 8-ми суточные проростки). Эти температуры приводят к схожей тенденции в синтезе БТШ в побегах и листьях. В тоже время, содержание БТШ16.9 зависит от стадии развития пшеницы. В нормальных условиях был отмечен синтез БТШ16.9 в побегах, но не в листьях. Сделано заключение, что адаптация 8-ми суточных проростков более длительный процесс (6-24 ч воздействия 37 и 39 ºC) по сравнению с 4-х суточными проростками (3-6 ч воздействия 37 и 39 ºC).
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39

Hassan, Md Quamrul, M. ShahabUddin Ahamad, Syed Ahmed, and M. A. Wahhab Chowdhury. "Comparative study of efficacy of brush cytology and transthoracic fine needle aspiration cytology in the diagnosis of bronchogenic carcinoma." Bangladesh Medical Research Council Bulletin 36, no. 1 (July 19, 2010): 37–39. http://dx.doi.org/10.3329/bmrcb.v36i1.4215.

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40

Mahmud, Kuasha, KM Nasiruddin, MA Hossain, and L. Hassan. "Development of Mutants in Sugarcane through Callus Culture." Plant Tissue Culture and Biotechnology 26, no. 1 (September 27, 2016): 123–30. http://dx.doi.org/10.3329/ptcb.v26i1.29773.

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The effects of different concentrations (0.0 M, 0.01 M, 0.02 M and 0.03 M for 24 hours treatment) of chemical mutagen like, ethyl methanesulfphonate (EMS) on callus derived from sugarcane var. Isd 37, Isd 39 and Isd 40 were investigated for in vitro plant regeneration. The highest number of shoots (58.33%) was reduced over control of Isd 40 followed by Isd 37 (57.62%) and Isd 39 (the lowest 56.06%), respectively due to the use of EMS for treating calli. The regeneration of mutant plantlets was achieved from EMS (0.01 M) treated calli obtained from leaf sheath explants on MS supplemented with 2, 4?D (3 mg/l) and 10% coconut water. Most of the mutant plants were developed from Isd 37. The developed mutant plants showed variation in tiller number, internode, green leaf, millable cane and stalk colour from the source variety of Isd 37.Plant Tissue Cult. & Biotech. 26(1): 123-130, 2016 (June)
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Sholekha, Larasyati, Entin Jubaedah, and Lia Nurcahyani. "THE EFFECT OF HYDROTHERAPY ON THE REDUCTION OF BLOOD PRESSURE IN PREGNANT WOMEN WITH HYPERTENSION AT THE PRIMARY HEALTH CAREASTANAJAPURA CIREBON DISTRICT IN 2019." International Seminar of Gender Equity Maternal and Child Health 1, no. 1 (July 8, 2021): 109–21. http://dx.doi.org/10.34305/gemic.v1i1.318.

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One of the causes of maternal mortality and morbidity is pregnancy induced hypertension (PIH). One of many hypertension management in pregnancy with non-pharmacological is hydrotherapy, which is soaking the feet using warm water for 20 minutes. This study aims to determine the differences in systolic and diastolic blood pressure in the hydrotherapy group with a temperature of 40o - 43 o compared to temperatures of 37 o - 39 o. The study using Quasi-Experimental non-randomized pre-test and post-test with control design on 22 hypertensive pregnant women using purposive sampling technique. Research instruments included observation sheets, sphygmomanometer, stethoscope, and digital water thermometer. Univariate and bivariate data analysis using the Wilcoxon and Mann-Whitney tests. This study showed difference of systolic blood pressure p value 0,000 and difference of diastolic p value 0,013 (p <0,05), therefore there were differences in systolic and diastolic blood pressure in the hydrotherapy group with a temperature of 40 o - 43 o compared to 37 o - 39 o. Hydrotherapy using temperature of 40 o - 43 o is better to use than temperature of 37 o - 39 o. Midwives can use hydrotherapy as an early treatment alternative for hypertensive pregnant women
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42

Kim, Kyoungrae, Blake A. Reid, Bohyun Ro, Caitlin A. Casey, Qifan Song, Shihuan Kuang, and Bruno T. Roseguini. "Heat therapy improves soleus muscle force in a model of ischemia-induced muscle damage." Journal of Applied Physiology 127, no. 1 (July 1, 2019): 215–28. http://dx.doi.org/10.1152/japplphysiol.00115.2019.

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Leg muscle ischemia in patients with peripheral artery disease (PAD) leads to alterations in skeletal muscle morphology and reduced leg strength. We tested the hypothesis that exposure to heat therapy (HT) would improve skeletal muscle function in a mouse model of ischemia-induced muscle damage. Male 42-wk-old C57Bl/6 mice underwent ligation of the femoral artery and were randomly assigned to receive HT (immersion in a water bath at 37°C, 39°C, or 41°C for 30 min) or a control intervention for 3 wk. At the end of the treatment, the animals were anesthetized and the soleus and extensor digitorum longus (EDL) muscles were harvested for the assessment of contractile function and examination of muscle morphology. A subset of animals was used to examine the impact of a single HT session on the expression of genes involved in myogenesis and the regulation of muscle mass. Relative soleus muscle mass was significantly higher in animals exposed to HT at 39°C compared with the control group (control: 0.36 ± 0.01 mg/g versus 39°C: 0.40 ± 0.01 mg/g, P = 0.024). Maximal absolute force of the soleus was also significantly higher in animals treated with HT at 37°C and 39°C (control: 274.7 ± 6.6 mN; 37°C: 300.1 ± 7.7 mN; 39°C: 299.5 ± 10 mN, P < 0.05). In the soleus, but not the EDL muscle, a single session of HT enhanced the mRNA expression of myogenic factors as well as of both positive and negative regulators of muscle mass. These findings suggest that the beneficial effects of HT are muscle specific and dependent on the treatment temperature in a model of PAD. NEW & NOTEWORTHY This is the first study to comprehensively examine the impact of temperature and muscle fiber type composition on the adaptations to repeated heat stress in a model of ischemia-induced muscle damage. Exposure to heat therapy (HT) at 37°C and 39°C, but not at 41°C, improved force development of the isolated soleus muscle. These results suggest that HT may be a practical therapeutic tool to restore muscle mass and strength in patients with peripheral artery disease.
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Mahmud, Kuasha, KM Nasiruddin, MA Hossain, and L. Hassan. "Screening sugarcane somaclones and their parent varieties against red rot (Colletotrichum falcatum) and assessment of Variability by RAPD and SSR markers." SAARC Journal of Agriculture 13, no. 2 (January 25, 2016): 173–82. http://dx.doi.org/10.3329/sja.v13i2.26578.

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The experiment was conducted to find out red rot disease causing pathogenic reactions of somaclones (R0) and their respective parents at BSRI farm in the cropping season 2011-2012. A total number of sugarcane genotypes 24 including 4 sugarcane varieties viz. Isd 37, Isd 38, Isd 39 and also Isd 40 were inoculated to screen red rot resistant levels (R = Resistant, MR = Moderately Resistant) to susceptible levels (S = Susceptible, MS = Moderately Susceptible, HS = Highly Susceptible) after 7 months of planting. As a result, Isd 37 variety (source/parent) and its somaclones CC–37–12 and CC–37–86 were found to be resistant while 7 somaclones showed moderately resistant reaction. Furthermore, somaclones of Isd 38 variety viz. CC–38–2 as moderately resistant, CC–38–10 as moderately susceptible and also CC–11(38)–8 as susceptible reaction were recorded while Isd 38 variety showed resistant reaction. On the other hand, Isd 39 and Isd 40 source varieties with their somaclones were found as resistant reaction against red rot pathogen. Some somaclones showed different reaction from their source varieties such as moderately resistant somaclones were obtained from resistant source variety Isd 37 while somaclones CC–38–2 as moderately resistant, CC–38–10 as moderately susceptible and somaclone CC–38–8 as susceptible were obtained from resistant source variety Isd 38 against red rot pathogens respectively. Besides, some somaclones showed similar reaction from their resistant source varieties Isd 37, Isd 39 and also Isd 40. It revealed that reaction against red rot pathogen, induced somaclones showed variation with their source varieties. Red rot resistance somaclones were isolated and assessed for the presence of variability through RAPD and SSR markers. Cluster and sub cluster formation verified the presence of variability in the red rot resistance somaclones with respect to the parent.SAARC J. Agri., 13(2): 173-182 (2015)
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Shivanagappa, Mamatha, Vinutha K. Veerabhadrappa, Deepthi Thandaveshwar, and Madhumitha Mahesh. "Elective caesarean section and neonatal outcome: an observational study from a tertiary hospital in Mysore, Karnataka, India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 1 (December 26, 2018): 14. http://dx.doi.org/10.18203/2320-1770.ijrcog20185127.

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Background: Globally 18.6 percent of all births occur by Caesarean Section (CS) and the trend is increasing. In India CS rates have risen from 2.9% in 1992 to 17.2% in 2015. The optimal timing of CS is still being investigated. Data with regard to elective CS and neonatal outcome from India is sparse and this study aimed to obtain the same in the setting of a South Indian Hospital. The objective was to evaluate neonatal outcome and NICU admissions in elective CSMethods: This was a retrospective study conducted at a tertiary care referral hospital and data collected was of deliveries conducted from Jan 2017 to July 2018. All term singleton pregnancies (>37 gestational weeks) scheduled for elective CS were included in the study.Results: A total of 3174 Caesarean Sections were performed during the study period of which 1087 were elective CS and 2087 were done on an emergent basis. Of these elective CS, 425 (39%) were performed at early term (37+0 until 38+6) and 662 (61%) were performed at full term (>39 weeks). Analysis of adverse neonatal outcomes revealed that a significantly higher rate of NICU admission, low birth weight, respiratory complications in newborns delivered at early term than in those delivered at full term.Conclusions: In the present study newborns delivered at 37- 38 weeks of gestation had a higher rate of NICU admission, low birth weight and respiratory complications compared to newborns delivered after 39 weeks of gestation. Neonatal outcome was found to be better in those elective CS done after 39 weeks in comparison to those delivered at early term (< 39 weeks).
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Zadeh-Vakili, Azita, and Payman Eshghi. "Detection of a Rare Mutation in An Iranian Family: Codons 37/38/39 (7 bp Deletion)." Hemoglobin 33, no. 6 (December 2009): 523–27. http://dx.doi.org/10.3109/03630260903343897.

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46

Boucher, Jean-Francois, Marie-Pierre Cayer, Lucie Boyer, Réal Lemieux, Chantal Proulx, and Nicolas Pineault. "Identification of the Mechanisms Responsible for the Increased Megakaryopoiesis at 39°C." Blood 108, no. 11 (November 16, 2006): 1128. http://dx.doi.org/10.1182/blood.v108.11.1128.1128.

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Abstract The future viability of ex vivo cell therapies will dependent largely on the optimization of culture processes leading to adequate cell production in a reasonable culture time. Toward this, we have previously reported that the megakaryocyte (MK) differentiation and the yield of MK and platelets produced ex vivo can be enhanced by culturing cord blood (CB) CD34+ cells at 39°C (Biotechnol Bioeng, 2004, 88). We are now working at better characterizing and identifying the mechanism(s) responsible for this phenomenon. First, we investigated whether this effect on cell expansion and differentiation was gradual, or whether it was rapidly induced. CB CD34+ cells were cultured in a media promoting MK differentiation at 39°C for various length of time before being placed at 37°C for a total of 14 days. Though it varied between samples, a minimum period of 4 days was required to observe most of the impacts, with the full qualitative and quantitative impacts obtained after an incubation of 7 days. Next, we analyzed the impact of the culture temperature on the cell cycle kinetics of CB cells. In short, cells grown at 39°C had a reduced mean doubling time during the first week of culture caused by a reduction in time spend in the G1 phase. This was evidenced by a, 1) decreased proportion of cells in G1 (P<0.05) and increased proportion in the S/G2/M phases (S/G2/M of 39.7±2.7% vs 37.3±1.9% (P=0.05)), 2) similar mitotic indexes (%G/M2, P=0.3), 3) comparable viability as determined by annexinV/PI staining (P=0.4) and, 4) increased BrdU incorporation in the first 5 days of culture (+6.9 ±0.7%, P<0.03 (n=2)). Next, we investigated whether transcription factors (TF) normally involved in MK differentiation could be implicated in the increased and accelerated MK differentiation observed at 39°C. The expression of 3 key MK TFs (NF-E2,GATA-1 and Fli-1) was assessed by quantitative PCR (Q-PCR) in cultures of CB CD34+ cells under conditions favoring MK differentiation, at 37 and 39°C. Although no major perturbations were detected, their maximal expression levels were reached faster at 39°C. These differences appear to be a consequence rather than the cause of the increased MK differentiation seen at 39°C, since these correlated with the earlier apparition of immature CD41+ MK and mature CD42+ MK in 39°C cultures. To identify other candidate genes, we used microarray analysis (Affymetrix, U133A 2.0) to compare the gene expression repertoire of CD41+-MK cultured at 39°C or 37°C for 7 days. Analysis of 2 experiments identified a total of 239 genes differentially expressed (116 upregulated). This gene list was corroborated by Q-PCR, which confirmed the changes in expression of 10 of 12 genes. Interestingly, PDGF-a, a cytokine reported to promote MK expansion, was among the genes whose expression was found increased at 39°C by 2.8-fold. Hence, we tested whether addition of PDGF to culture at 37°C could recapitulate the increased and/or accelerated MK differentiation kinetic seen at 39°C. However, PDGF failed to increase MK output at 37°C and had little impact on MK differentiation (n=3). In summary, our results link the increased CB cell expansion and accelerated differentiation kinetics observed at 39°C to a shortening of the G1 phase. Although culture of CB MK at 39°C leads to significant differences in gene expression profile, it had a minimal impact on key MK TFs. Present work is aimed at identifying the mechanism(s) responsible for the shorter time required for CB cells to progress or exit the G1 phase.
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Riera, Gregorio, Megan Galindo, and Mark Turrentine. "Platelet Counts in Uncomplicated Pregnancies at Term." American Journal of Perinatology 37, no. 06 (April 12, 2019): 621–25. http://dx.doi.org/10.1055/s-0039-1685447.

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Abstract Objective This study aimed to evaluate platelet counts at delivery in uncomplicated pregnancies between 37 and 41 weeks of gestation. Study Design Platelet counts in women 16 to 45 years of age from August 1, 2011, through May 15, 2018, with a singleton pregnancy that delivered from 370/7 to 416/7 weeks of gestation. Women with pregnancy-related complications, preexisting disorders, or on medications that could affect platelet counts were excluded. Results A total of 18,526 women had uncomplicated pregnancies with mean platelet count from 370/7 to 416/7 weeks of gestation of 220 × 109/L. The lower limit 95th percentile (2.5% quantile) was 120 × 109/L. Platelet counts decreased weekly from 37 to 41 weeks of gestation, becoming significant at 39 weeks of gestation and beyond, compared with 37 weeks (p < 0.01). Mean platelet counts: 225 × 109/L at 37 weeks, 223 × 109/L at 38 weeks, 219 × 109/L at 39 weeks, 218 × 109/L at 40 weeks, and 216 × 109/L at 41 weeks of gestation. Platelet counts of less than 150 × 109/L occurred in 9.7%. Conclusion Platelet counts in uncomplicated pregnancies decrease weekly from 37 to 41 weeks of gestation. This will be important to consider when serial platelet values are monitored for other indications.
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TILLOY-ELLUL, Anne, Francoise RAFFALLI-MATHIEU, and Matti A. LANG. "Analysis of RNA–protein interactions of mouse liver cytochrome P4502A5 mRNA." Biochemical Journal 339, no. 3 (April 26, 1999): 695–703. http://dx.doi.org/10.1042/bj3390695.

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In our previous studies we have identified a 37/39 kDa, pyrazole-inducible, cytochrome P4502A5 (CYP2A5) mRNA binding protein and provided evidence that it may play a role in the stabilization and processing of the RNA [Geneste, Rafalli and Lang (1996) Biochem. J. 313, 1029-1037; Thulke-Gross, Hergenhahn, Tilloy-Ellul, Lang and Bartsch (1998) Biochem. J. 331, 473-481]. Details of the RNA-protein interactions are, however, not known. In this report we have performed an analysis of the interaction between the CYP2A5 mRNA and the 37/39 kDa protein. With UV-cross linking experiments, using RNA probes corresponding to various parts of the CYP2A5 mRNA, and with antisense oligonucleotides complementary to certain areas of the 3ʹ-untranslated region (3ʹUTR), we could map the primary binding site to the tip of a 71 nt hair-pin loop at the 3ʹ-UTR. This analysis also showed that the protein may have more than one site of interaction with the RNA and/or that, within the binding region, there could be more than one protein molecule binding to the RNA. Analysis of the probable conformations of the various probes used in the UV cross-linking experiments, in combination with the estimated binding affinities of the protein to the different probes, suggests that important factors in the high-affinity binding are the UAG triplet flanked by GA-rich sequences at the tip of the hair-pin loop, in addition to the conformation of the loop itself. Within the binding region, similarities with known binding sites of heterogeneous nuclear ribonucleoprotein (hnRNP) A1 in other RNA molecules were revealed by sequence alignment analysis. Moreover, competition experiments with an oligoribonucleotide corresponding to a known high-affinity binding site of hnRNP A1, and immunoprecipitation of the UV cross-linked 37/39 kDa complex showed that the protein binding to the CYP2A5 mRNA could be hnRNP A1 or its close analogue. It was also shown that the 37/39 kDa protein binds with less affinity to CYP2A4 mRNA than to CYP2A5 mRNA. This is in accordance with experiments characterizing the binding site, since these two otherwise highly homologous genes are kown to have a three nucleotide difference within the region important for the high binding affinity. Since the response of CYP2A4 to pyrazole is known to be weak, as compared with CYP2A5, this observation provides further evidence for a regulatory role of the 37/39 kDa protein in CYP2A5 mRNA metabolism.
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Mao, Guanxian, Peng Xuxing, Wu Hao, Wang Junbing, Liu Suyue, Wu Qiang, Liu Ying, Qiang Ren, Jixian Liu, and Charles E. Melançon. "Mutational landscape of early-stage non-small cell lung cancer patients using a 451 gene panel." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e20048-e20048. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e20048.

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e20048 Background: Many studies have reported mutation landscapes of non-small cell lung cancer (NSCLC), but most of the data were from advanced-stage patients. This study reports the mutation landscape of early-stage NSCLC patients. Methods: Many studies have reported mutation landscapes of non-small cell lung cancer (NSCLC), but most of the data were from advanced-stage patients. This study reports the mutation landscape of early-stage NSCLC patients. Results: In all, 74 tDNA and ctDNA samples were analyzed. A total of 285 mutations were identified, including 174 in tDNA and 111 in plasma ctDNA. Genes with the highest -frequencies of mutations in tDNA were EGFR, TP53, KMT2B, BRAF, PIK3CA, CDKN2A, and KRAS,while TP53, EGFR, NOTCH3, PIK3CA, andATM were the genes with the highest frequencies of mutations in ctDNA. The detection rate of driver mutations in tDNA and ctDNA, respectively, were: 42.9% (15/35) and 12.8% (5/39) for EGFR, 5.7% (2/35) and 2.6% (1/39) for ALK, 5.7% (2/35) and 2.6% (1/39) for ERBB2, 11.4% (4/35) and 0%)0/39) for BRAF,5.7% (2/35) and 0%)0/39) for RET, 37% (13/35) and 23.1% (9/39) for TP53. Conclusions: In all, 74 tDNA and ctDNA samples were analyzed. A total of 285 mutations were identified, including 174 in tDNA and 111 in plasma ctDNA. Genes with the highest -frequencies of mutations in tDNA were EGFR, TP53, KMT2B, BRAF, PIK3CA, CDKN2A, and KRAS,while TP53, EGFR, NOTCH3, PIK3CA, andATM were the genes with the highest frequencies of mutations in ctDNA. The detection rate of driver mutations in tDNA and ctDNA, respectively, were: 42.9% (15/35) and 12.8% (5/39) for EGFR, 5.7% (2/35) and 2.6% (1/39) for ALK, 5.7% (2/35) and 2.6% (1/39) for ERBB2, 11.4% (4/35) and 0% )0/39) for BRAF,5.7% (2/35) and 0% )0/39) for RET, 37% (13/35) and 23.1% (9/39) for TP53.
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50

Dhungel, Sajina, Komal Raj Rijal, Bindeshwar Yadav, Binod Dhungel, Nabaraj Adhikari, Upendra Thapa Shrestha, Bipin Adhikari, Megha Raj Banjara, and Prakash Ghimire. "Methicillin-Resistant Staphylococcus aureus (MRSA): Prevalence, Antimicrobial Susceptibility Pattern, and Detection of mecA Gene among Cardiac Patients from a Tertiary Care Heart Center in Kathmandu, Nepal." Infectious Diseases: Research and Treatment 14 (January 2021): 117863372110373. http://dx.doi.org/10.1177/11786337211037355.

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Background: Methicillin Resistant Staphylococcus aureus (MRSA) is a significant human pathogen associated with nosocomial infections. mecA in the S. aureus is a marker of MRSA. The main objective of this study was to detect mecA and vanA genes conferring resistance in S. aureus among cardiac patients attending Sahid Gangalal National Heart Centre (SGNHC), Kathmandu, Nepal between May and November 2019. Methods: A total of 524 clinical samples (blood, urine, sputum) were collected and processed. Bacterial isolates were tested for antimicrobial susceptibility test (AST) and screening for MRSA was carried out by cefoxitin disc diffusion method. Minimum inhibitory concentration (MIC) of vancomycin for MRSA was established by agar dilution method and chromosomal DNA was extracted and used in polymerase chain reaction targeting the mecA and vanA genes. Results: Out of 524 specimens, 27.5% (144/524) showed bacterial growth. Among 144 culture positive isolates, S. aureus (27.1%; 39/144) was the predominant bacteria. Among 39 S. aureus isolates, all isolates were found resistant to penicillin followed by erythromycin (94.9%; 37/39), gentamicin (94.9%; 37/39) and cefoxitin (87.2%; 34/39). Out of 39 S. aureus, 87.2% (34/39) were MRSA. Among 34 MRSA, 8.8% (3/34) were vancomycin intermediate S. aureus (VISA). None of the MRSA was resistant to vancomycin. All of the 3 VISA isolates were obtained from inpatients. Of 39 S. aureus, 82.1% (32/39) harbored mecA gene. Similarly, the entire VISA isolates and 94.1% (32/34) of the MRSA isolates were tested positive for mecA gene. Conclusions: High prevalence of MRSA among the cardiac patients indicates the increasing burden of drug resistance among bacterial isolates. Since infection control is the crucial step in coping with the burgeoning antimicrobial resistance in the country, augmentation of diagnostic facilities with routine monitoring of drug resistance is recommended.
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