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1

Abd Alrazzak, Nour. "Synthesis of new azo compounds based on 4-aminosalicylic acid and study anti-corrosive activity." Bulletin of the Chemical Society of Ethiopia 38, no. 2 (2024): 473–79. http://dx.doi.org/10.4314/bcse.v38i2.14.

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New azo dyes were prepared from 4-amino-2-hydroxy-benzoic acid in two steps; the first step includes preparation the diazonium salt. Then, diazonium compound coupled with different aromatic compounds containing donating groups (orcinol, 2,6-dimethylphenol, hydroquinone, catechol, 1,2,4-triazole, 2-methyl-naphthol and 4-toluidine, respectively). The physical properties of synthesized compounds were studied like melting point and solubility. The target molecules were characterized using FTIR, NMR and CHNS techniques. The activity of the compounds 1, 3 and 5 as anticorrosion on carbon steel in 0.
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2

Fiocchi, M., F. Onori, A. Bazzano, et al. "Evolution of MAXI J1631–479 during the January 2019 outburst observed by INTEGRAL/IBIS." Monthly Notices of the Royal Astronomical Society 492, no. 3 (2020): 3657–61. http://dx.doi.org/10.1093/mnras/staa068.

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ABSTRACT We report on a recent bright outburst from the new X-ray binary transient MAXI J1631–479, observed in January 2019. In particular, we present the 30–200 keV analysis of spectral transitions observed with INTEGRAL/IBIS during its Galactic plane monitoring program. In the MAXI and BAT monitoring period, we observed two different spectral transitions between the high/soft and low/hard states. The INTEGRAL spectrum from data taken soon before the second transition is best described by a Comptonized thermal component with a temperature of kTe ∼ 30 keV and a high-luminosity value of $L_{2-2
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3

Wong, K. R., C. A. Berry, and M. G. Cogan. "Alpha 1-adrenergic control of chloride transport in the rat S1 proximal tubule." American Journal of Physiology-Renal Physiology 270, no. 6 (1996): F1049—F1056. http://dx.doi.org/10.1152/ajprenal.1996.270.6.f1049.

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To identify in vivo the specific alpha-adrenergic receptor mediating direct neural control of chloride transport in the rat S1 proximal convoluted tubule (PCT), the major effector site of neural regulation, microperfusion was employed in conjunction with the alpha 1- and alpha 2-adrenergic receptor antagonists, prazosin and rauwolscine. Using a glomerular ultrafiltrate-like perfusate, prazosin markedly inhibited chloride transport by -42% (302 +/- 10 to 176 +/- 5 peq.mm-1.min-1, P < 0.0001). Using a sodium chloride perfusate, which measures the active component of chloride absorption (J(Cl)
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4

Bouchou, Lynda Zaid, Zineeddine Chekired, and Faiza Marniche. "Contribution to the Study of The Pedofauna In Southern Algeria (Djelfa Forest, Algeria)." International Journal of Membrane Science and Technology 10, no. 3 (2023): 3241–55. http://dx.doi.org/10.15379/ijmst.v10i3.3265.

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This study compares the soil fauna populations of two Aleppo pine sites in the semi-arid bioclimatic zone. One is located at Moudjbara, and the other at Senalba Chergui in the steppe of the Wilaya of Djelfa. Analysis of the soil sample inventories revealed a total of 479 specimens belonging to 9 classes, 16 orders, 38 families and 41 species. The Moudjbara fauna remains the best represented in terms of abundance, with a rate of 53% of the total number, as well as in terms of richness for all taxa combined, 23 families and 26 species compared with 15 for each of the above-mentioned ranks. On th
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5

Ray-Coquard, Isabelle, Paul Haluska, Seamus O'Reilly, et al. "A multicenter open-label phase II study of the efficacy and safety of ganitumab (AMG 479), a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R) as second-line therapy in patients with recurrent platinum-sensitive ovarian cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5515. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5515.

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5515 Background: IGF signaling has been implicated in the pathogenesis and progression of ovarian cancer (OC). Single agent activity and safety of ganitumab (AMG 479), a fully human monoclonal antibody against IGF-1R that blocks binding of IGF1 and IGF2, were evaluated in asymptomatic patients with platinum-sensitive recurrent OC. Differential expression of IGF-1R pathway genes in OC underscores the potential of developing predictive biomarkers for patient selection. Methods: Pts with CA125 progression (GCIG criteria) and/or measurable disease per RECIST failing primary platinum-based therapy
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6

Chen, Shuiqing, Jusheng Gao, Huaihai Chen, et al. "The role of long-term mineral and manure fertilization on P species accumulation and phosphate-solubilizing microorganisms in paddy red soils." SOIL 9, no. 1 (2023): 101–16. http://dx.doi.org/10.5194/soil-9-101-2023.

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Abstract. Understanding soil phosphorus (P) transformation and turnover under various fertilization managements is important for evaluating sustainable P fertility and potential bioavailability in agriculture managements. Thus, long-term fertilization experiments (∼ 38 years) with the application of different inorganic and organic fertilizers in paddy red soils were conducted to determine the effect of different fertilizer applications on P pool accumulation and microbial communities, especially for phosphate-solubilizing microorganisms (PSMs). Long-term inorganic P (IP) fertilization increase
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7

Marjan, Ali, and Mahmood Shafiee. "Evaluation of Wind Resources and the Effect of Market Price Components on Wind-Farm Income: A Case Study of Ørland in Norway." Energies 11, no. 11 (2018): 2955. http://dx.doi.org/10.3390/en11112955.

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This paper aims to present a detailed analysis of the performance of a wind-farm using the wind turbine power measurement standard IEC61400-12-1 (2017). Ten minutes averaged wind data are obtained from LIDAR over the period of twelve months and it is compared with the 38 years’ data from weather station with the objective of determining the wind resources at the wind-farm. The performance of one of the wind turbines located in the wind-farm is assessed by comparing the wind power potential of the wind turbine with its actual power production. Our analysis shows that the wind farm under study i
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8

van der Linde, Annelieke A. A., Yvonne Schönbeck, Hetty J. van der Kamp, et al. "Evaluation of the Dutch neonatal screening for congenital adrenal hyperplasia." Archives of Disease in Childhood 104, no. 7 (2019): 653–57. http://dx.doi.org/10.1136/archdischild-2018-315972.

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BackgroundIn 2002, a nationwide screening for congenital adrenal hyperplasia (CAH) was introduced in the Netherlands. The aim of our study is to evaluate the validity of the neonatal screening for CAH and to assess how many newborns with salt-wasting (SW) CAH have already been clinically diagnosed before the screening result was known.MethodsRetrospective, descriptive study. The following data of patients with positive screening results since implementation of the screening programme were collected (1 January 2002 up until 31 December 2013): gestational age, sex, diagnosis, clinical presentati
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9

Liao, Wei, Matthew Paul Smeltzer, Jordan Goss, et al. "Lung cancer diagnosis rates (LCDR) in lung cancer screening (LCS) and incidental pulmonary nodule (IPN) cohorts in the Mississippi Delta." Journal of Clinical Oncology 43, no. 16_suppl (2025): 8002. https://doi.org/10.1200/jco.2025.43.16_suppl.8002.

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8002 Background: The LCDR in the CT screened cohort in the National Lung Screening Trial (NLST) was 1.1% over a median of 6.5 years follow up. We evaluated the LCDR in a regional US community. Methods: Prospective cohort study of patients in LCS and IPN programs in 22 facilities across a 125 county service area population. We compared LCDR over 3 years in LCS stratified by Lung-RADS (L-R) score (1 to 4X), IPN by nodule size (≤6, >6-15, >15-20, >20-30 mm) on initial CT scans. Comparisons used Chi-square tests, Wilcoxon tests, and Cox regression models with Hazard Ratios (HR) for lung c
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10

Montalban-Bravo, Guillermo, Kelly S. Chien, Sanam Loghavi, et al. "Landscape and Clinicopathologic Features of RAS Pathway Mutations in Chronic Myelomonocytic Leukemia." Blood 144, Supplement 1 (2024): 3204. https://doi.org/10.1182/blood-2024-208890.

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Introduction: Somatic mutations in RAS pathway genes are present in ~30% of patients with chronic myelomonocytic leukemia (CMML) and are usually associated with myeloproliferative features. Whether mutations in distinct RAS pathway genes share similar genomic context and have similar implications remains unknown. Such an understanding might inform future studies evaluating genotype-specific therapies (RAS-codon specific and pan-RAS inhibitors) or cooperative leukemogenic mechanisms. This multicenter study examines the landscape of RAS pathway mutations (RASMT) in CMML. Methods: Newly diagnosed
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11

Watson, Sara, Tyler J. Benning, Alessandro R. Marcon, et al. "Descriptions of Scientific Evidence and Uncertainty of Unproven COVID-19 Therapies in US News: Content Analysis Study." JMIR Infodemiology 4 (August 29, 2024): e51328. http://dx.doi.org/10.2196/51328.

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Background Politicization and misinformation or disinformation of unproven COVID-19 therapies have resulted in communication challenges in presenting science to the public, especially in times of heightened public trepidation and uncertainty. Objective This study aims to examine how scientific evidence and uncertainty were portrayed in US news on 3 unproven COVID-19 therapeutics, prior to the development of proven therapeutics and vaccines. Methods We conducted a media analysis of unproven COVID-19 therapeutics in early 2020. A total of 479 discussions of unproven COVID-19 therapeutics (hydrox
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12

Chauhan, Priyanshi, Naveen Gaur, Gangadhar Reddy Akula, and Satyanath Reddy Kodidala. "CORRELATION BETWEEN BLOOD GROUP, AGE & GENDER WITH COVID-19 INFECTION." Medical Science of Ukraine (MSU) 19, no. 2 (2023): 14–19. http://dx.doi.org/10.32345/2664-4738.2.2023.03.

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Background. Covid-19, conjointly referred to as severe acute metabolism syndrome appeared in December 2019 by a new Corona virus. The virus originated from Wuhan, the capital of China’s Hubei Province and unfold everywhere the globe and have become a worldwide pandemic due to lack of cure.
 Aim:To study the association of ABO Blood Group, Rh, Age and gender with and COVID-19 infection.
 Material and methods. This retrospective study was conducted after the approval college research committee of Teerthanker Mahaveer medical college and research center. The study period of this study i
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13

Balar, A. V., M. I. Milowsky, A. B. Apolo, et al. "Phase II trial of gemcitabine, carboplatin, and bevacizumab in chemotherapy-naive patients (Pts) with advanced/metastatic urothelial carcinoma (UC)." Journal of Clinical Oncology 29, no. 7_suppl (2011): 248. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.248.

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248 Background: Effective treatment for pts with advanced UC unfit to receive cisplatin-based therapy remains an unmet need. A recent phase III study showed limited benefit of gemcitabine-carboplatin (GC) alone (median OS 9.3 months) (DeSantis ASCO 2010). We recently identified the VEGF-axis as a viable pathway for UC treatment (JCO 2010;Mar 10). We propose that bevacizumab, a monoclonal antibody against VEGFR, may be safely added to GC and improve time to progression (TTP) in pts with advanced UC. Methods: Primary endpoints (N=47 planned enrollment) were median TTP, to test an improvement of
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14

Prieto-Peña, D., S. Remuzgo Martinez, F. Genre, et al. "AB0145 IgA VASCULITIS AND IgA NEPHROPATHY SHARE A SIMILAR IL33-IL1RL1 ASSOCIATION PATTERN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1201.2–1203. http://dx.doi.org/10.1136/annrheumdis-2022-eular.414.

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BackgroundIgA vasculitis (IgAV) and IgA nephropathy (IgAN) are inflammatory conditions that share pathogenic and molecular mechanisms [1] and may represent different outcomes of a continuous spectrum of the disease [2]. Interleukin (IL)-33 is a cytokine that exerts its biological functions by binding to its receptor, IL-1 receptor like 1 (IL-1RL1) [3]. Several lines of evidence demonstrate that genetic variants located both in IL33 and IL1RL1 genes are implicated in the increased risk of numerous immune-mediated diseases [4].ObjectivesTo determine whether IgAV and IgAN exhibit a different IL33
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15

Peirson, William L., James W. Walker, and Michael L. Banner. "On the microphysical behaviour of wind-forced water surfaces and consequent re-aeration." Journal of Fluid Mechanics 743 (March 5, 2014): 399–447. http://dx.doi.org/10.1017/jfm.2013.681.

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AbstractA detailed laboratory investigation of the mechanical and low-solubility gas coupling between wind and water has been undertaken using a suite of microphysical measurement techniques. Under a variety of wind conditions and in the presence and absence of mechanically generated short waves, approximately fetch-independent surface conditions have been achieved over short laboratory fetches of several metres. The mechanical coupling of the surface is found to be consistent with Banner (J. Fluid Mech. vol. 211, 1990, pp. 463–495) and Banner & Peirson (J. Fluid Mech. vol. 364, 1998, pp.
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16

Milevskaya, S. Y. "Production potential of photosynthesis in forest ecosystems of the low mountain Pokuttya (Ukrainian Carpathians)." Biosystems Diversity 24, no. 1 (2016): 15–25. http://dx.doi.org/10.15421/011603.

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The aim of the study was testing on the example of a model region a method of estimation of the production potential of forest ecosystems and the consequences of anthropogenic changes there. The object of study is a typical Carpathian lower mountain forest in the basin of the river Lyuchka, an area of 14,806 ha. It has long undergone considerable agricultural transformations. Studies were based on cartographic modeling of modern anthropogenically transformed biogeocenotic cover using large scale satellite images. The main types of biogeocenotical cover were defined according to the altitudinal
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17

Velinova, Sylvia, Rose Catchatourian, Shaji Kumar, S. Vincent Rajkumar, Alexandra Greenberg, and Suresh Singla. "Racial Disparities in Cytogenetic Characteristics and Outcome of Multiple Myeloma." Blood 118, no. 21 (2011): 1808. http://dx.doi.org/10.1182/blood.v118.21.1808.1808.

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Abstract Abstract 1808 Background: Approximately 50% of the Multiple Myeloma (MM) cases are associated with hyperdiploidy (Hyperdiploid MM, HDMM), usually of the odd numbered chromosomes. The majority of the remaining patients with MM have translocations involving the immunoglobulin heavy chain (IgH) locus on chromosome 14q32 (Translocated MM, TMM).(Fonseca R, Leukemia 2009;23:2210-21) However, most of these estimates are from studies done in predominantly white populations. MM is approximately two fold more common in blacks, and results from the phase 3 study of lenalidomide and dexamethasone
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18

Ryan, P., Y. Zhang, F. Liu, et al. "A Distribution-based Method for Assessing The Differences between Clinical Trial Target Populations and Patient Populations in Electronic Health Records." Applied Clinical Informatics 05, no. 02 (2014): 463–79. http://dx.doi.org/10.4338/aci-2013-12-ra-0105.

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SummaryObjective: To improve the transparency of clinical trial generalizability and to illustrate the method using Type 2 diabetes as an example.Methods: Our data included 1,761 diabetes clinical trials and the electronic health records (EHR) of 26,120 patients with Type 2 diabetes who visited Columbia University Medical Center of New-York Presbyterian Hospital. The two populations were compared using the Generalizability Index for Study Traits (GIST) on the earliest diagnosis age and the mean hemoglobin A1c (HbA1c) values.Results: Greater than 70% of Type 2 diabetes studies allow patients wi
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19

Malato, Alessandra, Francesco Acquaviva, Alessandra Santoro, et al. "Successful Salvage Treatment With Clofarabine and Cytarabine In Relapsed/Refractory Acute Myeloid Leukemia." Blood 122, no. 21 (2013): 5039. http://dx.doi.org/10.1182/blood.v122.21.5039.5039.

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Abstract Objectives Relapsed/refractory AML patients have a poor prognosis; allogeneic hematopoietic stem cell transplantation (HSCT) is the only chance in this setting to achieve long-term disease-free survival (1). It was previously established the activity of clofarabine plus cytarabine in AML relapse (clofarabine dosed once daily for 5 days with 40 mg/m2 followed 4 hours later by ara-C at 1 g/m2 per day)(2).However, modifications of this combination in AML therapy of relapsed/refractory patients warrant further evaluation. Therefore, our goal was to determine the efficacy and safety of clo
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20

Pedersen, Susanne B., Steen D. Kristensen, and Anne-Mette Hvas. "Measurement of Whole Blood Platelet Aggregation by Multiplate® Aggregometry Before and during Aspirin Treatment." Blood 110, no. 11 (2007): 3895. http://dx.doi.org/10.1182/blood.v110.11.3895.3895.

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Abstract The inhibition of platelet aggregation by aspirin (ASA) is fundamental in treatment of ischemic heart disease (IHD). Several studies report findings of normal platelet aggregation despite ASA treatment in some individuals, referred to as ASA resistance (AR). It has been hypothesized that AR increases the risk of a future ischemic event. We evaluated a new impedance method for measurement of platelet aggregation, Multiplate® aggregometry (MA), and compared this method to light aggregometry ad modum Born (OPA), with reference to repeatability and detection of AR. Blood samples from 43 I
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21

Hashem, N., J. O. Secher, J. H. Pryor, et al. "141 BOVINE EMBRYO DEVELOPMENT RATES ARE AFFECTED WHEN OOCYTES ARE MATURED IN DIFFERENT VIALS CONTAINING HEPES/BICARBONATE BUFFERED MEDIUM." Reproduction, Fertility and Development 29, no. 1 (2017): 179. http://dx.doi.org/10.1071/rdv29n1ab141.

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Laboratory ware for the in vitro-produced embryos is generally made from embryo-tested plastic instead of glass. The quality of the plastic is crucial for the outcome because plastic is often toxic to gametes (Nijs et al. 2009 Fertil. Steril. 92, 527–535). In addition, gas molecules permeate through the plastic at a rate that depends on a variety of factors, such as diffusion coefficient and thickness of the plastic. In an incubator with appropriate concentration of CO2 and vented culture vessels, the gas permeability of the plastic is not important. When oocytes are transported outside a cont
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Mishra, Asmita, Dana E. Rollison, Najla H. Al Ali, et al. "Obesity Is Poor Prognostic Factor in Lower Risk Myelodysplastic Syndrome." Blood 118, no. 21 (2011): 5018. http://dx.doi.org/10.1182/blood.v118.21.5018.5018.

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Abstract Abstract 5018 Background: Obesity was associated with a more than 2-fold greater risk of myelodysplastic syndrome (MDS) in a recent epidemiological study (Ma et al, Am J Epidemiol. 2009 June 15; 169(12): 1492–1499). The impact of obesity on outcome of disease in patients with an established diagnosis of MDS has not been studied. We examined the prognostic value of obesity in a large cohort of lower risk MDS patients treated at the Moffitt Cancer Center (MCC). Methods: Data were collected retrospectively from the Moffitt Cancer Center (MCC) MDS database and individual charts reviewed.
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23

Ali, Md Ashraf, Shuji Noguchi, Miteki Watanabe, Yasunori Iwao, and Shigeru Itai. "The antitumour drug 7-ethyl-10-hydroxycamptothecin monohydrate and its solid-state hydrolysis mechanism on heating." Acta Crystallographica Section C Structural Chemistry 72, no. 10 (2016): 743–47. http://dx.doi.org/10.1107/s2053229616014492.

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7-Ethyl-10-hydroxycamptothecin [systematic name: (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, SN-38] is an antitumour drug which exerts activity through the inhibition of topoisomerase I. The crystal structure of SN-38 as the monohydrate, C22H20N2O5·H2O, reveals that it is a monoclinic crystal, with one SN-38 molecule and one water molecule in the asymmetric unit. When the crystal is heated to 473 K, approximately 30% of SN-38 is hydrolyzed at its lactone ring, resulting in the formation of the inactive carboxylate form. The molecular arran
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24

Ferguson, N. S., and R. M. Gous. "The response of growing pigs to amino acids as influenced by environmental temperature: tryptophan." Animal Science 74, no. 1 (2002): 103–10. http://dx.doi.org/10.1017/s1357729800052267.

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AbstractAn experiment was performed to measure the response of young pigs to dietary tryptophan (TRP) concentrations and environmental temperatures. Seventy-two entire male Large White ✕ Landrace pigs were assigned to one of six dietary treatments (2·90 (T1), 2·46 (T2), 2·01 (T3), 1·57 (T4), 1·12 (T5) g/kg and T5 + supplemented TRP (T6)) and one of three temperature treatments (20, 25 and 30°C) at a mean starting live weight of 14·38 (s.e. 0·201)kg. Animals were given ad libitum access to food until a final weight of 26·42 (s.e. 0·479) kg. There were no significant interactions between tempera
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25

Romero, D., G. Romero, G. Veneranda, L. Filippi, D. Racca, and G. A. Bó. "18 PREGNANCY RATES IN LACTATING DAIRY COWS TREATED WITH GONADOTROPIN-RELEASING HORMONE-BASED SYNCHRONIZATION PROGRAMS AND INSEMINATED AT A FIXED TIME." Reproduction, Fertility and Development 25, no. 1 (2013): 156. http://dx.doi.org/10.1071/rdv25n1ab18.

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An experiment was designed to compare pregnancy rates in lactating dairy cows synchronized with a 7-day CIDR-Synch or a 5-day CIDR-Synch program and to determine if the addition of a second prostaglandin F2α (PGF) injection to the 7-day CIDR-Synch program would improve pregnancy rates following fixed-time AI (FTAI). The experiments were performed on 2 dairy farms in Argentina, with year-round calving and a mixed feeding system (35% grazing plus 65% corn silage and grain). Cows (n = 621) were 39.3 ± 6.5 days in milk (DIM, mean ± SD) when they were enrolled in the program, had 2.4 ± 1.5 lactatio
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26

Sanal, Salahattin M., Melissa J. Hanson, Morris S. Dees, et al. "Rituximab Induces High Response Rate and Prolonged Remission in Chronic Idiopathic Thrombocytopenic Purpura (ITP): A Retrospective Analysis." Blood 104, no. 11 (2004): 3956. http://dx.doi.org/10.1182/blood.v104.11.3956.3956.

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Abstract Background: Rituximab is a chimeric monoclonal antibody targeting CD 20+ B lymphocytes (Rastetter et al, 2004). Combination of rituximab with conventional chemotherapeutic agents has become the mainstay of treatment for B-cell Non-Hodgkin’s Lymphomas. The role of rituximab in treatment of immune mediated disorders is currently under investigation. Earlier studies have reported significant responses to rituximab in chronic idiopathic thrombocytopenic purpura patients, who are refractory to steroids and in some cases to splenectomy. (Cooper et al, 2004). Methods: We retrospectively revi
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27

Siddiqui, Abdur-Rahman, Armando Carboney Santiago, Kristin Martin, Jeanne N'Diaye, and Joaquin Rodriguez Lopez. "A Guide for the Electrochemical Stability of Thiolate Self-Assembled Monolayers on Gold in Various Electrolytes." ECS Meeting Abstracts MA2023-02, no. 65 (2023): 3185. http://dx.doi.org/10.1149/ma2023-02653185mtgabs.

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Self-assembled monolayers (SAMs) are widely used in surface chemistry to modify surfaces for various applications such as biosensing1, electronics2, and electrocatalysis3. SAMs are attractive due to their high surface coverage and stability. Although studies have been conducted to test the effects of temperature, air exposure, and solvent degradation on SAMs stability 4,5, the electrochemical stability of SAMs has not been as extensively studied. Existing literature on this topic mainly focuses on the reductive desorption limits of thiolate SAMs in alkaline conditions6,7. Recent work by Ramos
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28

Shadman, Mazyar, Talha Munir, Tadeusz Robak, et al. "Sustained Superiority of Zanubrutinib vs Bendamustine + Rituximab in Treatment-Naive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (TN CLL): 5-Year Follow-Up of Cohort 1 from the SEQUOIA Study." Blood 144, Supplement 1 (2024): 3249. https://doi.org/10.1182/blood-2024-194864.

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Introduction: SEQUOIA (NCT03336333) is a multicenter, open-label, randomized phase 3 study evaluating the safety and efficacy of the next-generation Bruton tyrosine kinase (BTK) inhibitor zanubrutinib (zanu) in TN CLL/SLL. Cohort 1 enrolled patients without del(17p) to zanu or bendamustine + rituximab (BR). At a median follow-up of 26.2 months, the primary analysis demonstrated that zanu had a superior progression-free survival (PFS) compared with BR. Presented here are long-term data with 5 years of overall study follow-up for cohort 1. Methods: As previously reported, patients without del(17
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29

Hamilton, Ira, Nicole Martin, James Liu, Emily DeFranco, and Robert Rossi. "Gestational Age and Birth Outcomes in Term Singleton Pregnancies Conceived With Infertility Treatment." JAMA Network Open 6, no. 8 (2023): e2328335. http://dx.doi.org/10.1001/jamanetworkopen.2023.28335.

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ImportanceDespite the increased perinatal risks associated with pregnancies conceived with infertility treatment, there are no recommendations for timing of delivery among this at-risk population.ObjectiveTo identify the gestational age at which the ongoing risks of stillbirth are optimally balanced with the risks of neonatal comorbidities and infant deaths in term singleton pregnancies conceived with infertility treatment.Design, Setting, and ParticipantsThis cohort study used birth and death data from January 1, 2014, to December 31, 2018, in the US obtained from the National Center for Heal
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30

Bhattacharyya, Debmalya, Maitreyee Bhattacharyya, Saswata Chatterjee, Abhijit Chowdhury, and Pramit Ghosh. "Transient Elastography of Liver in Hb E Beta Thalassemia: A Novel Tool to Determine Hepatic Iron Overload?" Blood 126, no. 23 (2015): 3368. http://dx.doi.org/10.1182/blood.v126.23.3368.3368.

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Abstract Introduction: Transient Elastography (TE) of liver is a well established tool to measure liver stiffness, mainly used for assessment of hepatic fibrosis due to chronic hepatitis. Liver biopsy is the gold standard test for measurement of liver iron concentration (LIC) whereas T2* MRI is the best available non-invasive method for the same in thalassemia. We intended to use hepatic TE as an alternative cheaper tool to assess hepatic iron overload so that it can be applied to larger number of patients. Objective: To assess degree of liver stiffness by TE in patients with HbE beta thalasse
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31

Lee, Kristin M., Ellen Olszewski, Brianna D. Yund, and Bonita P. Klein-Tasman. "53 Concurrent Cognitive Predictors of School Age Academic Functioning in Children with Neurofibromatosis Type 1." Journal of the International Neuropsychological Society 29, s1 (2023): 658–59. http://dx.doi.org/10.1017/s1355617723008287.

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Objective:Children with neurofibromatosis type 1 (NF1) commonly have academic problems. While the neuropsychological profile of children with NF1 is variable, NF1 results in difficulties in a variety of cognitive domains including intellectual functioning, attention, executive functioning. Previous studies have suggested that cognitive functioning may relate to academic functioning in children with NF1; however, the evidence is limited and warrants further examination. Thus, this study will investigate the contribution of several cognitive domains (intellectual functioning, attention, working
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32

Takeyama, Masahiro, Keiji Nogami, Shoko Furukawa, and Midori Shima. "Identification of a Factor X-Interactive Site on the Factor VIII A2 Domain." Blood 128, no. 22 (2016): 3760. http://dx.doi.org/10.1182/blood.v128.22.3760.3760.

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Abstract We have experienced a case of acquired hemophilia A with inhibitor recognizing only a factor (F) VIII A2 epitope, and reported the inhibitory mechanism for disappearing FVIII activity (Blood, 124, 4226, 2014). In summary, the patient's inhibitor IgG bound to FVIII A2N (residue 372-562) fragment and inhibited Arg372 cleavage in FVIII by FXa, suggesting that FX(a) bound to FVIII A2 domain. ELISA-based assay showed that FVIII A2 fragment bound to FX (Kd; 338 nM). We hypothesized that FVIII A2 residues 400-429 might be FX binding site according to the 3-D model of FVIII molecule, and prep
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33

Estey, Elihu H., X. M. Wang, Peter Thall, et al. "Plausibility of Delaying Induction Therapy in Untreated AML." Blood 104, no. 11 (2004): 879. http://dx.doi.org/10.1182/blood.v104.11.879.879.

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Abstract Experience suggests that many physicians regard AML as a disease requiring urgent treatment, which should begin within 1–3 days of diagnosis. This practice was lent support by an ECOG trial in pts age above 55, which suggested that a delay of 3–5 days in initiating therapy resulted in a lower CR rate (38% in 235 pts vs. 50% in 113 pts, p=.03, Blood2004; 103: 479–485). The delay was due to logistical factors inherent in a blinded randomization to priming with GM-CSF vs. placebo in the 235 pts; in contrast priming, which ultimately had no effect on CR rate, was not studied in the initia
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34

Smiley, R. W., G. P. Yan, and Z. A. Handoo. "First Record of the Cyst Nematode Heterodera filipjevi on Wheat in Oregon." Plant Disease 92, no. 7 (2008): 1136. http://dx.doi.org/10.1094/pdis-92-7-1136b.

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Plant and soil samples from an irrigated winter wheat (Triticum aestivum) field near Imbler (Union County), OR were evaluated for root diseases during April 2007. The field exhibited patches with as much as 90% plant mortality. Previous crops were winter wheat (2004), chickpea (Cicer arietinum, 2005), and spring wheat (cv. Jefferson, 2006). Stubble was baled and removed, and the field was cultivated before replanting to winter wheat cv. Chukar in October. Patches of stunted seedlings (three- to five-leaf stage) appeared in March 2007. Stunted seedlings exhibited chlorotic or necrotic lower lea
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35

Siddiqui, Muhammad Zain, Tae Uk Han, Young-Kwon Park, Young-Min Kim, and Seungdo Kim. "Catalytic Pyrolysis of Tetra Pak over Acidic Catalysts." Catalysts 10, no. 6 (2020): 602. http://dx.doi.org/10.3390/catal10060602.

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The thermal and catalytic pyrolysis of two kinds of Tetra Pak waste (TP-1 and TP-2) over three different acidic catalysts—HZSM-5(SiO2/Al2O3, 30), HBeta (38), and Al-MCM-41(20)—were investigated in this study. Tetra Pak (TP) wastes consist of composite material comprising kraft paper, polyethylene (PE) film, and aluminum foil. Thermal decomposition behaviors during the pyrolysis of TPs were monitored using a thermogravimetric (TG) analyzer and tandem micro reactor-gas chromatography/mass spectrometry (TMR-GC/MS). Neither the interaction between the non-catalytic pyrolysis intermediates of kraft
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36

William, David R. "Progress in inorganic chemistry: Bioinorganic chemistry volume 38, S J Lippard (ed), 535 pages. £28.30. ISBN 0-471-5 and 0-471-52945-1 (paperback)." Applied Organometallic Chemistry 7, no. 1 (1993): 75. http://dx.doi.org/10.1002/aoc.590070110.

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37

Do, Truong Van, and Xin-Fen Gao. "Taxonomic revision of the genus Flemingia (Leguminosae) from Indo-Chinese floristic region." Phytotaxa 429, no. 1 (2020): 1–38. https://doi.org/10.11646/phytotaxa.429.1.1.

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Do, Truong Van, Gao, Xin-Fen (2020): Taxonomic revision of the genus Flemingia (Leguminosae) from Indo-Chinese floristic region. Phytotaxa 429 (1): 1-38, DOI: 10.11646/phytotaxa.429.1.1, URL: http://dx.doi.org/10.11646/phytotaxa.429.1.1
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38

吴, 仲林. "A(B′_(1/2)B″_(1/2)O_3系统有序参数的相互关系". Chinese Science Bulletin 38, № 5 (1993): 475–78. http://dx.doi.org/10.1360/csb1993-38-5-475.

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39

Papadopoulou, Anastasia, Usha L. Katari, Ulrike Gerdemann, et al. "Safety and Clinical Efficacy Of Rapidly-Generated Virus-Specific T Cells With Activity Against Adv, EBV, CMV, HHV6 and BK Virus Administered After Allogeneic Hematopoietic Stem Cell Transplant." Blood 122, no. 21 (2013): 148. http://dx.doi.org/10.1182/blood.v122.21.148.148.

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Abstract Viral infections remain a major cause of morbidity and mortality after allogeneic HSCT. We and others have demonstrated that the adoptive transfer of virus-specific T cells (VSTs) specific for EBV, CMV and Adv antigens can treat infections that are impervious to conventional therapies, but broader implementation and extension to additional problematic viruses has been limited by competition between viral antigens and time-consuming/laborious manufacturing. We therefore developed a simplified 10-day system for generating a single preparation of VSTs with activity against 12 antigens fr
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40

Napiroon, Tiwtawat, Kongkanda Chayamarit, Sally Dawson, Walter Till, and Henrik Balslev. "A synopsis of Lasianthus (Lasiantheae, Rubiaceae) in Thailand and two additional new species." Phytotaxa 439, no. 1 (2020): 1–38. https://doi.org/10.11646/phytotaxa.439.1.1.

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Napiroon, Tiwtawat, Chayamarit, Kongkanda, Dawson, Sally, Till, Walter, Balslev, Henrik (2020): A synopsis of Lasianthus (Lasiantheae, Rubiaceae) in Thailand and two additional new species. Phytotaxa 439 (1): 1-38, DOI: 10.11646/phytotaxa.439.1.1, URL: http://dx.doi.org/10.11646/phytotaxa.439.1.1
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41

Rai, Parul, Guolian Kang, Ronak Naik, et al. "Longitudinal Effect of Hydroxyurea Therapy on Left Ventricular Diastolic Function in Sickle Cell Anemia." Blood 134, Supplement_1 (2019): 1006. http://dx.doi.org/10.1182/blood-2019-130905.

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Background: Cardiac abnormalities in sickle cell anemia (SCA) include pan-chamber dilation, biventricular hypertrophy, ventricular diastolic dysfunction and elevated pulmonary artery pressures. Diastolic dysfunction in SCA has been reported with a variable prevalence, ranging from 11-77%. Its onset is in childhood, and data show an increase in prevalence with age [Pediatr Blood Cancer 2017, 64 (11): e26607]. While its etiology has remained elusive, it has been shown to be associated with early mortality in adults [J Am Coll Cardiol 2007, 49(4): 472-479] and decreased exercise capacity in child
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42

Beyarslan, A., M. Yurtcan, Ö. Çetin, and M. Aydogdu. "A Study on Braconidae and Ichneumonidae from Ganos Mountains (Thrace Region, Turkey) (Hymenoptera, Braconidae, Ichneumonidae)." Linzer biologische Beiträge 38, no. 1 (2006): 409–22. https://doi.org/10.5281/zenodo.5433331.

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Beyarslan, A., Yurtcan, M., Çetin, Ö., Aydogdu, M. (2006): A Study on Braconidae and Ichneumonidae from Ganos Mountains (Thrace Region, Turkey) (Hymenoptera, Braconidae, Ichneumonidae). Linzer biologische Beiträge 38 (1): 409-422, DOI: 10.5281/zenodo.5433331
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43

Ramakrishnan, Vanitha, Linlin Xu, Jason C. Paik, et al. "Broad Superiority of Zanubrutinib (Zanu) Over Bendamustine + Rituximab (BR) Across Multiple High-Risk Factors: Biomarker Subgroup Analysis in the Phase 3 SEQUOIA Study in Patients With Treatment-Naive (TN) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) without del(17p)." Blood 142, Supplement 1 (2023): 1902. http://dx.doi.org/10.1182/blood-2023-174543.

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Introduction Zanu is a Bruton tyrosine kinase (BTK) inhibitor with high potency, selectivity, and efficacy and a favorable toxicity profile. In the phase 3 SEQUOIA study (NCT03336333; Tam et al. Lancet Oncol. 2022), zanu treatment demonstrated superior progression-free survival (PFS) in TN patients (pts) with CLL/SLL and without del(17p) (cohort 1) compared with BR treatment (hazard ratio [HR], 0.42; 95% CI, 0.28-0.63; 2-sided P<.0001). We evaluated PFS in both treatment arms in pt subgroups based on various biomarkers, including several known negative prognostic factors for CLL. Method
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44

Duran, B. J., R. V. Sala, P. L. J. Monteiro, et al. "101 Treatment with gonadotrophin-releasing hormone on Day 7 or 21 does not reduce pregnancy loss in dairy heifers receiving invitro-produced embryos." Reproduction, Fertility and Development 32, no. 2 (2020): 176. http://dx.doi.org/10.1071/rdv32n2ab101.

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Previous research has shown that induction of an accessory corpus luteum (CL) by administration of gonadotrophin-releasing hormone (GnRH) on Day 5 increases circulating progesterone and reduces pregnancy loss between Days 33 and 60 in heifers receiving invitro-produced (IVP) embryos. Therefore, the objective of the present study was to determine whether timing of induction of an accessory CL influenced pregnancy loss in IVP recipients. Holstein heifers (n=1,658) were synchronized using a modified 5-day CIDR CO-Synch protocol. Briefly, heifers received an intravaginal progesterone device (CIDR)
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45

Del Coso, Juan, Juan A. Ramírez, Gloria Muñoz, et al. "Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match." Applied Physiology, Nutrition, and Metabolism 38, no. 4 (2013): 368–74. http://dx.doi.org/10.1139/apnm-2012-0339.

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The purpose of this study was to investigate the effectiveness of a caffeine-containing energy drink in enhancing rugby players' physical performance during a simulated match. A second purpose was to determine the urinary caffeine excretion derived from the energy drink intake. In a randomized and counterbalanced order, 26 elite rugby players (mean ± SD for age and body mass, 25 ± 2 y and 93 ± 15 kg) played 2 simulated rugby games (2 × 30 min) 60 min after ingesting (i) 3 mg of caffeine per kilogram of body mass in the form of an energy drink (Fure, ProEnergetics) or (ii) the same drink withou
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46

Rosenblum, Daniel, and Steven Hirschfeld. "Threshold of Credibility: New Approach to Licensing Acute Leukemia Therapy." Blood 104, no. 11 (2004): 3128. http://dx.doi.org/10.1182/blood.v104.11.3128.3128.

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Abstract Acute leukemia is a disease with a rapidly fatal outcome in the absence of effective treatment. In recent decades dramatic improvements in the treatment of acute leukemia have resulted in cure for some and an energetic search for similar progress for the remainder. Cure is expected for the majority of children and young adults with favorable prognostic factors and subsets of patients, such as those with acute promyelocytic leukemia (APL). Unfortunately, death from leukemia or its complications is the usual outcome for the majority of the 11,000 adults who are diagnosed each year. To f
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47

& Abdulrasool, Annon. "EFFECT OF GAMMA RADIATION AND ETHYL METHANESULFONATE (EMS) ON POTATO SALT STRESS TOLERANCE IN VITRO." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 51, no. 4 (2020): 982–90. http://dx.doi.org/10.36103/ijas.v51i4.1076.

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An experiment was conducted in the Date Palm Research Units labs / College of Agricultural Engineering Sciences / University of Baghdad to assess the tolerance toward salinity stress in potato after two mutagens treatments in vitro. Potato cv. Arizona and Rivera nodal segments were irradiated with four dosages of gamma rays at 0, 10, 20, and 30 Gray and immersed in (EMS) with four concentrations included 0, 10, 20, and 30 mM. The survival rates after mutagenesis treatments were calculated and 449 lines were obtained. The lines were tested for salinity tolerance by growing in MS medium suppleme
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48

Du, Cailian, Bo Yang, Jianhui Wu, and Shaukat Ali. "Identification and Virulence Characterization of Two Akanthomyces attenuatus Isolates Against Megalurothrips usitatus (Thysanoptera: Thripidae)." Insects 10, no. 6 (2019): 168. http://dx.doi.org/10.3390/insects10060168.

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Megalurothrips usitatus (Bagnall) is one of the most harmful pests of leguminous plants. In order to expand our knowledge on the infection of M. usitatus by entomopathogenic fungi, two newly identified isolates of Akanthomyces attenuatus (Zare & Gams) were tested for their pathogenicity against M. usitatus. Both isolates of A. attenuatus (SCAUDCL-38 and SCAUDCL-56) were isolated from soil and were identified by morphological and molecular analyses. The adult females of M. usitatus were treated with five different concentrations (1 × 104, 1 × 105, 1 × 106, 1 × 107, and 1 × 108 conidia/mL) o
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49

Ningsih, Sherly Kasuma Warda. "SINTESIS DAN KARAKTERISASI NANOPARTIKEL ZnO DOPED Cu2+ MELALUI METODA SOL-GEL." EKSAKTA: Berkala Ilmiah Bidang MIPA 18, no. 02 (2017): 39–51. http://dx.doi.org/10.24036/eksakta/vol18-iss02/51.

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Penelitian mengenai sintesis nanopartikel ZnO undoped dan doped Cu2+ telah dilakukan melalui metoda sol-gel, dengan menggunakan zink (II) asetat dihidrat sebagai prekursor, isopropanol sebagai pelarut, dan monoethanolamin sebagai zat aditif. Tujuan penelitian ini adalah menentukan struktur, ukuran partikel, spektra FTIR dan band gap, serta menjelaskan morfologi permukaan ZnO doped Cu2+. Pada penelitian ini dilakukan penambahan dopan Cu2+ dengan variasi konsentrasi 3%.. Nanopartikel ZnO undoped dan doped Cu2+ diperoleh dari hasil pengeringan sol Zn(OH)2 pada suhu 110? selama 1 jam dan dikalsina
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50

Hussain, Mehmood. "CLINICAL PROFILES AND OUTCOMES OF PATIENTS ADMITTED WITH MODERATE TO CRITICAL CORONAVIRUS DISEASE 2019 (COVID-19)." PAFMJ 71, no. 2 (2021): 694–701. http://dx.doi.org/10.51253/pafmj.v71i2.5842.

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Objective: To evaluate various demographic, clinical, radiological and hematological manifestations of moderate to critical coronavirus disease 2019 (COVID-19) and to assess its complications and outcomes in the Pakistani population.
 Study Design: Retrospective observational study.
 Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi, from Apr to Jul 2020.
 Methodology: Demographic, clinical, radiological and hematological data of 600 consecutive patients were retrieved and analyzed from hospital registry.
 Results: Overall, 449 (74.8%) patients had at
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