Academic literature on the topic '4-amino-N-(1; 3-thiazol-2-yl)benzenesulfonamide'

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Journal articles on the topic "4-amino-N-(1; 3-thiazol-2-yl)benzenesulfonamide"

1

Valarmathy, Govindaraj, Ramanathan Subbalakshmi, Rajendran Nithya, Ragu Nandhini, Balachandaran Sabarika, and Elanchleiyan Aarthy. "Synthesis, Spectral Characterisation and Cytotoxic Evaluation of Substituted Sulfonamide Schiff Bases." Indian Journal of Science and Technology 14, no. 34 (2021): 2731–41. https://doi.org/10.17485/IJST/v14i34.888.

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Abstract <strong>Objectives:</strong>&nbsp;To synthesize Schiff bases i.e 4-((2-hydroxybenzylidene)-amino&ndash;N-(5-methyl-1,2-oxozol-3- yl)benzene sulphonamide (L1), 4-((2-hydroxy benzylidene)-amino-N-(thiazol-yl)benzene sulphonamide (L2), 4-((2-hydroxybenzylidene)amino-N-(pyridin-2-yl)benzene sulphonamide by theaction of 2-hydroxybenzaldehyde with sulfathiazole/ sulfamethoxazole/ sulfapyridine in ethanolic media.&nbsp;<strong>Methods:</strong>&nbsp;The Schiff bases obtained were characterized by analytical data, IR, UV, 1H- NMR, 13C-NMR, Mass spectrum and monitored for cytotoxic activity ag
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2

Ghorab, Mostafa, Fatma Ragab, Helmy Heiba, Marwa El-Gazzar, and Mostafa El-Gazzar. "Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives." Acta Pharmaceutica 61, no. 4 (2011): 415–25. http://dx.doi.org/10.2478/v10007-011-0040-4.

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Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives Sulfonamides and quinoxaline derivatives possess many types of biological activities and have been recently reported to show substantial antitumor activity. This paper reports the synthesis of novel thioureido sulfaquinoxaline derivatives. All the newly synthesized compounds were evaluated for their in vitro anticancer activity against a human liver cell line (HEPG2) and showed higher activity than the reference drug doxorubicin.
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Gupta, Apoorva, and Anand K. Halve. "Synthesis & Antifungal Screening of Novel Azetidin-2-ones." Open Chemistry Journal 2, no. 1 (2015): 1–6. http://dx.doi.org/10.2174/1874842201502010001.

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A new series of 4-[3-chloro-2-(4-hydroxy-3-methoxybenzyllidene)-4-oxoazetidin-1-yl]amino-N-(substituted)benzenesulfonamide, 4-{3-chloro-2-[5-methoxy-2-nitro-4-(prop-2-en-1-yloxy)benz yllidene]-4-oxoazetidin-1-yl}]amino}-N-(substituted)benzenesulfonamide and 4-{3-chloro-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)benzylidene]-4-oxoazetidin-1-yl}amino}-N-(substituted) benzenesulfonamide were synthesized using appropriate synthetic route. The chemical structures of all the synthesized compounds were deduced on the basis of elemental analysis and spectroscopic data. The antifungal activity of the syn
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Asiri, Abdullah M., Hassan M. Faidallah, Khalid A. Alamry, Seik Weng Ng, and Edward R. T. Tiekink. "4-[5-(Furan-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide." Acta Crystallographica Section E Structure Reports Online 68, no. 4 (2012): o1168—o1169. http://dx.doi.org/10.1107/s1600536812011920.

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In the title compound, C14H10F3N3O3S, there are significant twists in the molecule, as seen in the values of the dihedral angles between the pyrazole ring and each of the furan [31.1 (2)°] and benzene rings [55.58 (10)°]. The amino N atom occupies a position almost normal to the benzene ring [N—S—Car—Car(ar = aromatic) torsion angle = 83.70 (19)°]. One amino H atom forms a hydrogen bond to the tricoordinate pyrazole N atom and the other interacts with a sulfonamide O atom, forming a supramolecular chain along [010]. The chains are consolidated into a supramolecular layersviaC—H...O interaction
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5

Tailor, Sanjay M., and Urmila H. Patel. "Hirshfeld surface analysis of sulfameter (polymorph III), sulfameter dioxane monosolvate and sulfameter tetrahydrofuran monosolvate, all at 296 K." Acta Crystallographica Section C Structural Chemistry 71, no. 11 (2015): 944–53. http://dx.doi.org/10.1107/s2053229615017520.

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The ability of the antibacterial agent sulfameter (SMT) to form solvates is investigated. The X-ray crystal structures of sulfameter solvates have been determined to be conformational polymorphs. Both 1,4-dioxane and tetrahydrofuran form solvates with sulfameter in a 1:1 molar ratio. 4-Amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide (polymorph III), C11H12N4O3S, (1), has two molecules of sulfameter in the asymmetric unit cell. 4-Amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide 1,4-dioxane monosolvate, C11H12N4O3S·C4H8O2, (2), and 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide tet
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6

Arman, Hadi D., Trupta Kaulgud, and Edward R. T. Tiekink. "4-Amino-N-(2,3-dihydro-1,3-thiazol-2-ylidene)benzenesulfonamide–2,4,6-tris(pyridin-2-yl)-1,3,5-triazine (1/1)." Acta Crystallographica Section E Structure Reports Online 70, no. 4 (2014): o402—o403. http://dx.doi.org/10.1107/s1600536814004838.

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The sulfathiazole molecule in the title 1:1 co-crystal, C9H9N3O2S2·C18H12N6, adopts an approximate L-shape [dihedral angle between the five- and six-membered rings = 86.20 (9)°] and features an intramolecular hypervalent S...O interaction [2.8666 (15) Å]. Overall, the triazine molecule has the shape of a disk as the pendant pyridine rings are relatively close to coplanar with the central ring [dihedral angles = 18.35 (9), 6.12 (9) and 4.67 (9)°]. In the crystal packing, a linear supramolecular chain aligned along [01-1] is formed as a result of amino–pyridyl N—H...N hydrogen bonding withsyn-di
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7

Vázquez Rivera, Alondra, Heather Donald, Mounia Alaoui-El-Azher, et al. "Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities." Biomolecules 14, no. 7 (2024): 819. http://dx.doi.org/10.3390/biom14070819.

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The ribonuclease H (RNase H) active site of HIV-1 reverse transcriptase (RT) is the only viral enzyme not targeted by approved antiretroviral drugs. Using a fluorescence-based in vitro assay, we screened 65,239 compounds at a final concentration of 10 µM to identify inhibitors of RT RNase H activity. We identified 41 compounds that exhibited 50% inhibitory concentration (i.e., IC50) values &lt; 1.0 µM. Two of these compounds, 2-(4-methyl-3-(piperidin-1-ylsulfonyl)phenyl)benzo[d]isothiazol-3(2H)-one (1) and ethyl 2-(2-(3-oxobenzo[d]isothiazol-2(3H)-yl)thiazol-4-yl)acetate (2), which both share
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8

Hülya, Akgün, Kaya Betül, Mulazim Yusuf, et al. "Synthesis and Biological Activity Studies of Substituted N-(1,3-Dioxohexahydro-2H-Isoindol-2-yl) Benzenesulfonamide Derivatives." Pharmaceutical and Chemical Journal 6, no. 2 (2019): 91–102. https://doi.org/10.5281/zenodo.13936063.

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In this study, ten substituted <em>N </em>- ([1,3-dioxoindolin-2-yl] phenyl] sulfonyl) structures (compound <strong>1-10</strong>), which seven of them were original synthesized using conventional and microwave synthesis methods. &nbsp;In the first method the cis-1,2-cyclohexanecarboxylic anhydride and sulfa derivatives reacted under&nbsp; reflux for 2-3 hours in acetic acid. In the second method the cis-1,2-cyclohexanecarboxylic anhydride and sulfa derivatives were dissolved in DMF and radiated by microwave. Structure elucidation of the synthesized compounds were confirmed by UV, IR <sup>1</s
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Özbey, Süheyla, Arzu Akbaş, Gülgün Ayhan-Kilcigil, and Rahmiye Ertan. "Antibacterial 4-amino-N-(5-methylisoxazol-3-yl)-N-[(4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl]benzenesulfonamide." Acta Crystallographica Section C Crystal Structure Communications 61, no. 9 (2005): o559—o561. http://dx.doi.org/10.1107/s0108270105023759.

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10

Al-Khatib, Kassim, Robert Parker, and E. Patrick Fuerst. "Rose (Rosa dilecta) Response to Simulated Herbicide Drift." HortTechnology 2, no. 3 (1992): 394–98. http://dx.doi.org/10.21273/horttech.2.3.394.

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This study evaluated the response of rose to different herbicides applied as simulated drift. Chlorsulfuron {2-chloro-N-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamide}, thifensulfuron {3[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]-2-thiophenecarboxylic acid}, bromoxynil(3,5-dibromo-4-hydroxybenzonitrile), 2,4-D[(2,4-dichlorophenoxy)acetic acid], glyphosate [N-(phosphonomethyl) glycine], and a combination of 2,4-D and glyphosate were applied over the top of established rose plants at 1/3, 1/10,1/33, and 1/100 of the maximum labeled rate f
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