Relevant bibliographies by topics / 4-azaindazole

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic '4-azaindazole'

Author: Grafiati
Published: 7 July 2024
Last updated: 31 July 2025

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Journal articles on the topic "4-azaindazole"

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Faarasse, Soukaina, Saïd El Kazzouli, Otmane Bourzikat, et al. "Palladium‐Catalyzed Regioselective C−H Arylation of 4‐Azaindazole at C3, C5 and C7 Positions." Advanced Synthesis & Catalysis 363, no. 16 (2021): 3937–45. http://dx.doi.org/10.1002/adsc.202001421.

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Wu, Tianze, Yi Chen, Yimin Gong, et al. "A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells." Molecules 30, no. 11 (2025): 2347. https://doi.org/10.3390/molecules30112347.

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N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo [3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide, namely, FD274, is a promising 7-azaindazole-based PI3K inhibitor candidate with high antitumor efficacy against acute myeloid leukemia and reduced cardiotoxicity in the zebrafish model. To advance its clinical translation, in this work, we conducted comprehensive assessments of the cardiotoxicity of FD274 and preliminarily investigated its synergistic antitumor effects with an FLT3 inhibitor, Gilteritinib. The cardiotoxicity profile of FD274, as well as its bioisostere FD268 (positive cont
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3

Faarasse, Soukaina, Saïd El Kazzouli, Otmane Bourzikat, et al. "Front Cover Picture: Palladium‐Catalyzed Regioselective C−H Arylation of 4‐Azaindazole at C3, C5 and C7 Positions (Adv. Synth. Catal. 16/2021)." Advanced Synthesis & Catalysis 363, no. 16 (2021): 3867. http://dx.doi.org/10.1002/adsc.202100859.

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4

Alam, Ryan M., and John J. Keating. "“Walking the nitrogen around the ring”: Chemical synthesis and spectroscopic characterization of novel 4‐, 5‐, 6‐, and 7‐azaindazole analogs of the synthetic cannabinoid receptor agonist MDMB‐PINACA." Drug Testing and Analysis 14, no. 2 (2021): 277–97. http://dx.doi.org/10.1002/dta.3180.

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Viktorova, viktoria Vladimirovna, Dmitrii L'vovich Obydennov, Аlsu F. Mustafina, Maria V. Ulitko, Mikhail Yurievich Kornev, and Vyacheslav Sosnovskikh. "Regioselective synthesis of 5-azaindazoles based on the intramolecular amination reaction of 5-acyl-4-pyridones with hydrazines." Organic & Biomolecular Chemistry, 2025. https://doi.org/10.1039/d4ob01969e.

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The labile tautomerism of N-unsubstituted 5-acyl-4-pyridones, which exist in the form of 4-pyridone or 4-hydroxypyridine depending on the solvent, has been demonstrated. This equilibrium determines reactivity of pyridones and ability...
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6

Swift, Elizabeth C., Zachary S. Sales, Dongpei Wu, Anastassia Matviitsuk, Daniel J. Pippel, and Terry P. Lebold. "Synthesis of Highly Functionalized 4-Iodo-7-azaindazoles via Condensation/Diels–Alder/Retro-Diels–Alder Cyclization of Iodoalkynones and 2-Hydrazineylpyrimidines." Organic Letters, November 22, 2023. http://dx.doi.org/10.1021/acs.orglett.3c03481.

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7

Zheng, Lei, Zulihuma Aimaiti, Lu Long, Chuang Xia, Wenya Wang, and Zhong-Zhen Zhou. "Discovery of 4-Ethoxy-6-chloro-5-azaindazoles as Novel PDE4 Inhibitors for the Treatment of Alcohol Use Disorder and Alcoholic Liver Diseases." Journal of Medicinal Chemistry, December 29, 2023. http://dx.doi.org/10.1021/acs.jmedchem.3c02087.

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Dissertations / Theses on the topic "4-azaindazole"

1

Nassiri, Sarah. "Fonctionnalisations régiosélectives de N-oxyde de pyrazolopyridines via des réactions de C-H activation pallado-catalysées." Electronic Thesis or Diss., Orléans, 2024. https://theses.univ-orleans.fr/prive/accesESR/2024ORLE1007_va.pdf.

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Les réactions de C-H activation représentent aujourd’hui une approche attrayante pour l’élaboration de nouveaux systèmes hétérocycliques pouvant avoir des applications dans divers domaines notamment en biologie et en pharmacie. L’objectif de cette thèse est le développement de nouvelles stratégies permettant de fonctionnaliser sélectivement des hétérocycles azotés par des réactions de C-H activation au moyen de la catalyse à base de métaux de transition.Dans la première partie, nous avons mis au point une méthodologie de synthèse, permettant la fonctionnalisation régiosélective en ortho de la
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