Relevant bibliographies by topics / 4-chloroquinoline

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic '4-chloroquinoline'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "4-chloroquinoline"

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Motiwala, Hashim F., Raj Kumar, and Asit K. Chakraborti. "Microwave-Accelerated Solvent- and Catalyst-Free Synthesis of 4-Aminoaryl/alkyl-7-chloroquinolines and 2-Aminoaryl/alkylbenzothiazoles." Australian Journal of Chemistry 60, no. 5 (2007): 369. http://dx.doi.org/10.1071/ch06391.

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An efficient synthesis of 4-aminoaryl/alkyl-7-chloroquinolines and 2-aminoaryl/alkylbenzothiazoles has been developed by microwave-accelerated regioselective aromatic nucleophilic substitution of 4,7-dichloroquinoline and 2-chlorobenzothiazole with aromatic and aliphatic amines under solvent-free conditions in the absence of any added protic or Lewis acid catalyst. Chemoselective reaction with the amino group in preference to the phenolic hydroxy group was observed. Thus, the treatment of 4,7-dichloroquinoline (1 equiv.) with a mixture of aniline (2 equiv.) and phenol (2 equiv.) afforded exclu
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Le, Trong Duc, Ngoc Nam Pham, and Tien Cong Nguyen. "Preparation and Antibacterial Activity of Some New 4-(2-Heterylidenehydrazinyl)-7-chloroquinoline Derivatives." Journal of Chemistry 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/4301847.

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N-(4-Substituted phenyl)acetamides, which were prepared from acetic anhydride and p-substituted anilines, were utilized as precursors for reactions to Vilsmeier-Haack reagent to form 6-substituted-2-chloroquinoline-3-carbaldehydes 3a–c. Meanwhile, a similar reagent was applied to 1-[1-(4-substituted phenyl)ethylidene]-2-phenylhydrazines as substrates, which were synthesized from phenylhydrazine hydrochloride and p-substituted acetophenones, and 1,3-diarylpyrazole-4-carbaldehydes 3d–f were observed as a result. Reactions between the aldehydes 3a–f and 7-chloro-4-hydrazinylquinoline 2, obtained
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Barlin, GB, SJ Ireland, TMT Nguyen, B. Kotecka, and KH Rieckmann. "Potential Antimalarials. XVIII. Some Mono- and Di-Mannich Bases of 3-[7-Chloro(and trifluoromethyl)quinolin-4-ylamino]phenol." Australian Journal of Chemistry 46, no. 11 (1993): 1685. http://dx.doi.org/10.1071/ch9931685.

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Syntheses are reported for mono- and di-Mannich base derivatives of 3-[7-chloro(and trifluoro-methyl)quinolin-4-ylamino]phenols by Mannich reaction on 3-[7-chloro(and trifluoromethyl )-quinolin-4-ylamino]phenols or by condensation of Mannich base derivatives of 3-aminophenol, prepared from 3-nitrophenol, with the appropriate 4-chloroquinoline. The antimalarial activity of 3-(7′-chloroquinolin-4′-ylamino)-2,6-bis[ pyrrolidin-1″-ylmethyl -(or piperidin-1″-ylmethyl)]phenol against the FC-27 isolate of Plasmodium falciparum was comparable to that of chloroquine, and it was not significantly dimini
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Kit, O. I., V. I. Minkin, E. A. Lukbanova, et al. "Evaluation of the cytotoxic activity and toxicity of a tropolone derivative with a potential antitumor effect." Bulletin of Siberian Medicine 21, no. 2 (2022): 60–66. http://dx.doi.org/10.20538/1682-0363-2022-2-60-66.

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The aim. To study the toxicity of 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone in vitro and in vivo.Materials and methods. 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone was synthesized using a method for expanding the o-quinone cycle during the reaction between 5-nitro-2,6,8-trimethyl4-chloroquinoline and 3,4,5,6-tetrachloro-1,2-benzoquinone while boiled in dioxane. An in vitro experiment was carried out in the human A549 cell line. Cell viability was assessed using the MTT colorimetric assay by reducing the optical density of th
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Devi, Kavita, Yumna Asmat, Sonika Jain, Swapnil Sharma, and Jaya Dwivedi. "An Efficient Approach to the Synthesis of Novel Oxazolidinones as Potential Antimicrobial Agents." Journal of Chemistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/252187.

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Oxazolidinone, either mononuclear or condensed with other heterocyclics, has established its importance in medicinal chemistry. A variety of biological activities have been reported by oxazolidinone derivatives. The present work describes the synthesis of several oxazolidinone derivatives, 3-(2-(7-chloroquinoline-4-ylamino)ethyl)-2-imino-5-(4-chloro/nitro/methoxy benzylidene)oxazolidin-4-one 4(a–c) and 4-(2-(7-chloroquinolin-4-ylamino)ethyl)-2(4-chloro/nitro/methoxy-benzylidene)-1,6-diox-4,9-di-azaspiro[4,4]nonane-3,8-dione 5(a–c). Synthesized compounds (1, 3, 4a, 5a, and 5c) were screened aga
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da Silva, Manuel A. V. Ribeiro, Maria Agostinha R. Matos, and Luísa M. P. F. Amaral. "Standard molar enthalpies of formation of 2-chloroquinoline, 4-chloroquinoline, 6-chloroquinoline and 4,7-dichloroquinoline by rotating-bomb calorimetry." Journal of Chemical Thermodynamics 38, no. 1 (2006): 49–55. http://dx.doi.org/10.1016/j.jct.2005.03.011.

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Baumer, Vyacheslav N., Oleg V. Shishkin, Igor V. Ukrainets, Svetlana G. Taran, and Jaradat Nidal Amin. "Ethyl 4-butylamino-2-chloroquinoline-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 57, no. 3 (2001): o254—o255. http://dx.doi.org/10.1107/s1600536801002276.

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Kumara, Tholappanavara H. Suresha, Gopalpur Nagendrappa, Nanjappa Chandrika, et al. "Reactions between arylhydrazinium chlorides and 2-chloroquinoline-3-carbaldehydes: molecular and supramolecular structures of a hydrazone, a 4,9-dihydro-1H-pyrazolo[3,4-b]quinoline and two 1H-pyrazolo[3,4-b]quinolines." Acta Crystallographica Section C Structural Chemistry 72, no. 9 (2016): 670–78. http://dx.doi.org/10.1107/s205322961601278x.

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Hydrazone derivatives exhibit a wide range of biological activities, while pyrazolo[3,4-b]quinoline derivatives, on the other hand, exhibit both antimicrobial and antiviral activity, so that all new derivatives in these chemical classes are potentially of value. Dry grinding of a mixture of 2-chloroquinoline-3-carbaldehyde and 4-methylphenylhydrazinium chloride gives (E)-1-[(2-chloroquinolin-3-yl)methylidene]-2-(4-methylphenyl)hydrazine, C17H14ClN3, (I), while the same regents in methanol in the presence of sodium cyanoborohydride give 1-(4-methylphenyl)-4,9-dihydro-1H-pyrazolo[3,4-b]quinoline
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Singh, Jay Bahadur, Kalpana Mishra, Tanu Gupta, and Radhey M. Singh. "Copper-catalyzed cascade reaction: synthesis of pyrimido[4,5-b]quinolinones from 2-chloroquinoline-3-carbonitriles with (aryl)methanamines." New Journal of Chemistry 42, no. 5 (2018): 3310–14. http://dx.doi.org/10.1039/c7nj04689h.

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Cu-catalyzed cascade reaction of 2-chloroquinoline-3-carbonitriles with benzyl amines using sodium hydroxide in aerobic atmosphere has been developed for the synthesis of pyrimido[4,5-b]quinoline-4-ones.
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Gomes, Ligia R., John Nicolson Low, James L. Wardell, Laura N. de F. Cardoso та Marcus V. N. De Souza. "Substituted 4-alkoxy-7-Cl-quinolines exhibiting π–π stacking". Acta Crystallographica Section C Crystal Structure Communications 69, № 2 (2013): 191–94. http://dx.doi.org/10.1107/s0108270113001510.

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The molecules of 4-allyloxy-7-chloroquinoline, C12H10ClNO, (I), 7-chloro-4-methoxyquinoline, C10H8ClNO, (II), and 7-chloro-4-ethoxyquinoline, C11H10ClNO, (III), are all planar. In all three structures, π–π interactions between the quinoline ring systems are generated by unit-cell translations along theaaxes, irrespective of space group. These structures are the first reported for 4-alkoxyquinolines.
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Dissertations / Theses on the topic "4-chloroquinoline"

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Zishiri, Vincent Kudakwashe. "Synthesis, antimalarial evaluation and structure-activity relationship in a series of dibenzlmethylamine (Dibemethin) derivatives of 4-amino-7-chloroquinoline." Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/6280.

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Includes abstract.<br>Includes bibliographical references (leaves 138-154).<br>A series of twelve 4-amino-7-chloroquinolines containing (N, N-dibenzylmethylamine) dibemethin side chains attached to the amino group of the quinoline were synthesized by reaction of aminomethyl dibemethins with 4,7-dichloroquinoline to give “dibemethinoquines”. The attachment between the quinoline ring and the side chain was varied from ortho, to meta to para. The aminomethyl dibemethin side chains were synthesized using the Staudinger reduction of azides or the reductive amination via oxime of an aldehyde. Deriva
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Jacobs, Leon. "Synthesis and biological evaluation of novel ferroquine and phenylequine analogues." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/79836.

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Gutierrez, Rivas Joyce Elena. "Synthèse d'analogues de 7-chloroquinoléinyl-4-alkylidènes et benzoates avec une potentielle activité cytotoxique-antitumorale et antimalarique." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0956/document.

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Ces travaux de thèse décrivent la synthèse d'une série de dérivés du noyau 7-chloroquinoléine substitués en position 4. Ces nouveaux composés résultent de l’introduction de motifs thio- et amino-alcool, suivie d’une réaction de couplage avec des acides benzoïques ou des indanones diversement substitués. Les composés soufrés ont également fait l’objet d’oxydation en sulfones. Cent sept (107) dérivés de la 7-chloroquinoléine ont ainsi été synthétisés, puis soigneusement purifiés et complètement caractérisés en vue de leur évaluation biologique en tant qu’agents cytotoxiques-antitumoraux et antim
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Calixto, Stephane Lima. "Atividade in vitro de derivados de 4-amino-7-cloroquinolina em Leishmania sp e possíveis mecanismos de morte do parasito." Universidade Federal de Juiz de Fora (UFJF), 2018. https://repositorio.ufjf.br/jspui/handle/ufjf/6660.

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Submitted by Geandra Rodrigues (geandrar@gmail.com) on 2018-04-10T18:23:45Z No. of bitstreams: 1 stephanelimacalixto.pdf: 3753314 bytes, checksum: 81fe7e710d2a4f72d60b8c74e25040de (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2018-04-11T15:17:14Z (GMT) No. of bitstreams: 1 stephanelimacalixto.pdf: 3753314 bytes, checksum: 81fe7e710d2a4f72d60b8c74e25040de (MD5)<br>Made available in DSpace on 2018-04-11T15:17:14Z (GMT). No. of bitstreams: 1 stephanelimacalixto.pdf: 3753314 bytes, checksum: 81fe7e710d2a4f72d60b8c74e25040de (MD5) Previous iss
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Сільванович, Олександр Олександрович. "Синтез потенційних біорегуляторів на основі похідних (7-хлорохінолін-4-сульфаніл)карбонових кислот". Магістерська робота, 2020. https://dspace.znu.edu.ua/jspui/handle/12345/4204.

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Сільванович О. О. Синтез потенційних біорегуляторів на основі похідних (7-хлорохінолін-4-сульфаніл) карбонових кислот : кваліфікаційна робота магістра спеціальності 102 "Хімія" / наук. керівник О. А. Бражко. Запоріжжя : ЗНУ, 2020. 62 с.<br>UA : В роботі 62 сторінки, 4 таблиці, 20 рисунків, було використано 64 літературних джерела, 39 з них на іноземній мові. Об’єктом дослідження є (7-хлорохінолін-4-сульфаніл)карбонові кислоти та їх функціональні похідні. Предметом дослідження є синтез, ідентифікація та фізико-хімічні властивості (7-хлорохінолін-4-сульфаніл)карбонових кис
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Book chapters on the topic "4-chloroquinoline"

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Otuokere, I. E., L. O. Okpara, K. C. Amadi, C. O. Alisa, A. Okoyeagu, and F. C. Nwadire. "4-N-(7-Chloroquinolin-4-yl)-1-N,1-N-diethyl petane-1,4-diamine Ti Complex: Synthesis and Characterization." In Technological Innovation in Pharmaceutical Research Vol. 3. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/tipr/v3/1827e.

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Conference papers on the topic "4-chloroquinoline"

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Jauhari, Smita, and Bhupendra Mistry. "“Study of the Inhibitive Effect of Novel Quinoline Schiff Base on Corrosion of Mild Steel in HCl Solution”." In CORROSION 2013. NACE International, 2013. https://doi.org/10.5006/c2013-02326.

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Abstract Schiff base 4-Chloro-N-[(2-chloroquinolin-3-yl)methylene]aniline was synthesized, and its inhibitive effect for mild steel in 1M HCl solution was investigated by weight loss measurement and electrochemical tests.From the weight loss measurements and electrochemical tests, it was observed that the inhibition efficiency increases with the increase in the Schiff base concentration and reaches a maximum at the optimum concentration. This is further confirmed by the decrease in corrosion rate. It is found that the system follows Langmuir adsorption isotherm.
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Saraiva, Maiara, Roberta Krüger та Diego Alves. "Synthesis of Quinoline-Triazoil Carboxylates by Organocatalytic Cycloaddition of β-Ketoesters and 4-Azido-7-Chloroquinoline". У 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013811191913.

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Dube, Pritam N., and Yogita B. Thombare. "Synthesis and Evaluation of Novel 5-Arylidene-2-(7-chloroquinolin-6-yl)-3-(pyrimidin-2-yl) Thiazolidin-4-Ones as Anti-Microbial Agents." In ECSOC 2024. MDPI, 2024. https://doi.org/10.3390/ecsoc-28-20120.

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