Academic literature on the topic '4-dihydroxyphenylalanine'

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Journal articles on the topic "4-dihydroxyphenylalanine"

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Wolfovitz, Efrat, Ehud Grossman, Carol J. Folio, Harry R. Keiser, Irwin J. Kopin, and David S. Goldstein. "Derivation of Urinary Dopamine from Plasma Dihydroxyphenylalanine in Humans." Clinical Science 84, no. 5 (May 1, 1993): 549–57. http://dx.doi.org/10.1042/cs0840549.

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1. Dihydroxyphenylalanine is the precursor of all endogenous catecholamines. In laboratory animals, renal uptake and decarboxylation of circulating dihydroxyphenylalanine accounts for most of dopamine in urine. Dopamine is natriuretic, and in rats, dietary salt loading increases renal dihydroxyphenylalanine uptake by increasing the rate of entry (spillover) of dihydroxyphenylalanine into arterial plasma. In experimental animals and in humans, dietary salt loading increases urinary excretion of dihydroxyphenylalanine and dopamine. The present study examined in humans the extent to which circula
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Matsushita, Naoko, Yoshimi Misu, and Yoshio Goshima. "In vivo antagonism of the behavioral responses to L-3-,4-dihydroxyphenylalanine by L-3-,4-dihydroxyphenylalanine cyclohexyl ester in conscious rats." European Journal of Pharmacology 605, no. 1-3 (March 2009): 109–13. http://dx.doi.org/10.1016/j.ejphar.2008.12.032.

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Adamiec, J., K. Cejpek, J. Rössner, and J. Velíšek. "Novel Strecker degradation products of tyrosine and dihydroxyphenylalanine." Czech Journal of Food Sciences 19, No. 1 (February 7, 2013): 13–18. http://dx.doi.org/10.17221/6568-cjfs.

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Tyrosine was oxidised with either potassium peroxodisulphate or glyoxal. Volatile reaction products were isolated and analysed by GC/FID and GC/MS, derivatised with diazomethane and analysed by the same methods. Eight reaction products were identified. The major products were the expected Strecker aldehyde (4-hydroxyphenylacetaldehyde) and its lower homologue 4-hydroxybenzaldehyde. They were followed by 1-(4-hydroxyphenyl)-3-propionaldehyde, phenylacetaldehyde, benzaldehyde, phenol, 4-hydroxybenzoic, and benzoic acid. Analogously, the oxidation of 3,4-dihydroxyphenylalanine yielded the corresp
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GOLDSTEIN, DAVID S. "Plasma 3, 4-Dihydroxyphenylalanine (Dopa) and Catecholamines in Neuroblastoma or Pheochromocytoma." Annals of Internal Medicine 105, no. 6 (December 1, 1986): 887. http://dx.doi.org/10.7326/0003-4819-105-6-887.

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Chen, Lisha, Fengxia Chang, Lingchen Meng, Meixian Li, and Zhiwei Zhu. "A novel electrochemical chiral sensor for 3,4-dihydroxyphenylalanine based on the combination of single-walled carbon nanotubes, sulfuric acid and square wave voltammetry." Analyst 139, no. 9 (2014): 2243–48. http://dx.doi.org/10.1039/c4an00098f.

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Xiong, Xiong, Ding Hai Li, and Yue Feng Wang. "Differences in Thermal Stability and Surface Morphology of Dopa and Dopamine Graft Compound." Advanced Materials Research 641-642 (January 2013): 951–54. http://dx.doi.org/10.4028/www.scientific.net/amr.641-642.951.

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L-3, 4-Dihydroxyphenylalanine(DOPA) has a unique catechol moiety found in adhesive proteins in marine organisms, such as mussels and polychaete, which results in strong adhesion in aquatic conditions. Conventional efforts incorporating DOPA into polymer is grafting methacrylate anhydride. For this reason, we synthesized the new catechol intermediate N-methacryloyl 3,4-dihydroxyl-phenylamine and analyzed the surface morphology and thermal stability of it.
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Tamura, Sadaaki, Teruhiko Nitoda, and Isao Kubo. "Effects of Salicylic Acid on Mushroom Tyrosinase and B16 Melanoma Cells." Zeitschrift für Naturforschung C 62, no. 3-4 (April 1, 2007): 227–33. http://dx.doi.org/10.1515/znc-2007-3-412.

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Abstract Salicylic acid slightly inhibited the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase noncompetitively without being oxidized. In contrast, 4-hydroxybenzoic acid did not inhibit this enzymatic oxidation if a longer reaction time was observed, although it suppressed the initial rate of the oxidation to a certain extent. Neither acid showed noticeable effects on cultured murine B16-F10 melanoma cells except weak cytotoxicity.
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Forster, Christine, George Naik, and Paul W. Armstrong. "Noradrenaline biosynthesis and metabolism during development and recovery from pacing-induced heart failure in the dog." Canadian Journal of Physiology and Pharmacology 72, no. 1 (January 1, 1994): 45–49. http://dx.doi.org/10.1139/y94-008.

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We have modified an assay utilizing ion-pair high-performance liquid chromatography with electrochemical detection to measure dihydroxyphenylalanine and dyhydroxyphenylglycol simultaneously with noradrenaline. We measured these agents at control, 1 and 3 weeks following the onset of rapid ventricular pacing, as well as 4 weeks after the cessation of a 3-week period of pacing. Our findings were as follows. Plasma noradrenaline increased significantly at 1 week and increased further after 3 weeks of pacing (control, 202 ± 16; 1 week, 528 ± 62; 3 weeks, 750 ± 139 pg∙mL−1). Plasma dihydroxyphenyla
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Nakajima, Naoko, Syuntaro Hiradate, and Yoshiharu Fujii. "Characteristics of Growth Inhibitory Effect of L-3, 4-Dihydroxyphenylalanine (L-DOPA) on Cucumber Seedlings." Journal of Weed Science and Technology 44, no. 2 (1999): 132–38. http://dx.doi.org/10.3719/weed.44.132.

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Nakamura, Shinichi, Yoshio Goshima, and Yoshimi Misu. "Transmitter-like release of endogenous 3, 4-dihydroxyphenylalanine from the rat striatum investigated by microdialysis." Neuroscience Research Supplements 14 (January 1991): S147. http://dx.doi.org/10.1016/s0921-8696(06)80429-9.

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Dissertations / Theses on the topic "4-dihydroxyphenylalanine"

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Nelson, Michelle Amy, and n/a. "Protein Bound 3,4-Dihydroxyphenylalanine as a Signal for Enhanced Antioxidant Defences." University of Canberra. n/a, 2008. http://erl.canberra.edu.au./public/adt-AUC20081209.125208.

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Protein-bound 3,4-dihydroxyphenylalanine (PB-DOPA), a long-lived, redox-active product of protein oxidation, is capable of functioning as both a pro- and anti-oxidant. A number of in vitro and in vivo studies have demonstrated a toxic, non-toxic or even beneficial effect of free DOPA, however little investigation has examined the physiological activity of PB-DOPA. Furthermore, as free DOPA is currently the major treatment available for Parkinson?s disease, most studies have focused on the effect of DOPA within neurological cells or tissues, although the presence of PB-DOPA in other locations,
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(7360475), Sabyasachy Mistry. "MASS SPECTROMETRIC DETECTION OF INDOPHENOLS FROM THE GIBBS REACTION FOR PHENOLS ANALYSIS." Thesis, 2020.

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<p><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a>ABSTRACT</a></p> <p>Phenols are ubiquitous in our surroundings including biological molecules such as L-Dopa metabolites, food components, such as whiskey and liquid smoke, etc. This dissertation describes a new method for detecting phenols, by reaction with Gibbs reagent to form indophenols, followed by mass spectrometric detection. Unlike the standard Gibbs reaction which uses a colorimetric approach, the use of mass spectrometry allows for simultaneous detection of differently substituted phenols. The procedure is
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Book chapters on the topic "4-dihydroxyphenylalanine"

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"3,4-Dihydroxyphenylalanine reductive deaminase." In Class 4–6 Lyases, Isomerases, Ligases, 377–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-85707-5_78.

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