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Journal articles on the topic '4-dioxides'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Fallon, Gary D., Craig L. Francis, Katarina Johansson, Andris J. Liepa, and Ruth C. J. Woodgate. "N,N-Dialkyl-N´-Chlorosulfonylchloroformamidines in Heterocyclic Synthesis. II. Thiazolo-, Thiadiazolo-, and Oxadiazolo-Fused [1,2,4,6]Thiatriazine Dioxides." Australian Journal of Chemistry 58, no. 12 (2005): 891. http://dx.doi.org/10.1071/ch05070.

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N,N-dialkyl-N′-chlorosulfonylchloroformamidines 1 were treated with 2-aminothiazoline, 2-aminothiazoles, 2-aminobenzothiazoles, 2-amino-1,3,4-thiadiazoles, and 2-amino-1,3,4-oxadiazoles to give a 6,7-dihydrothiazolo[3,2-b][1,2,4,6]thiatriazine dioxide 3, a 6,7-dihydrothiazolo[2,3-c][1,2,4,6]thiatriazine dioxide 4, thiazolo[3,2-b][1,2,4,6]thiatriazine dioxides 5, [1,2,4,6]thiatriazino[3,2-b]benzothiazole dioxides 7, a [1,2,4,6]thiatriazino[3,4-b]benzothiazole dioxide 8, [1,3,4]thiadiazolo[2,3-c][1,2,4,6]thiatriazine dioxides 10, [1,3,4]thiadiazolo[3,2-b][1,2,4,6]thiatriazine dioxides 11, [1,3,4

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2

Cablewski, Teresa, Erin J. Carter, Craig L. Francis, Andris J. Liepa, and Michael V. Perkins. "N,N-Dialkyl-N′-Chlorosulfonyl Chloroformamidines in Heterocyclic Synthesis. III. Pyrido- and Pyridazo-Fused [1,2,4,6]Thiatriazine Dioxides." Australian Journal of Chemistry 60, no. 2 (2007): 105. http://dx.doi.org/10.1071/ch06367.

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N,N-Dialkyl-N′-chlorosulfonylchloroformamidines 1 reacted with 2-aminopyridines 2 to give novel pyrido[1,2-b][1,2,4,6]thiatriazine dioxides 3 and pyrido[2,1-c][1,2,4,6]thiatriazine dioxides 4. Reaction of 1 with 3-aminopyridazines 5 afforded pyridazo[3,2-c][1,2,4,6]thiatriazine dioxides 6 and a pyridazo[2,3-b][1,2,4,6]thiatriazine dioxide 7. The compounds 6 and 7 are derivatives of new ring systems.

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3

Hryhoriv, Halyna V., Dmitry A. Lega, and Leonid A. Shemchuk. "1,2-Benzoxathiin-4(3H)-one 2,2-dioxide – an underinvestigated building block with a high synthetic and pharmacological potential: synthesis, chemical properties, biological activity." Journal of Organic and Pharmaceutical Chemistry 19, no. 2(74) (2021): 4–28. http://dx.doi.org/10.24959/ophcj.21.234271.

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Aim. To analyze the available literature data on the methods of synthesis, chemical transformations and the biological activity of derivatives containing a sultone core – 1,2-benzoxathiin-4(3H)-one 2,2-dioxide – and to show the possibilities of their further use in the construction of new molecular systems with attractive pharmacological properties. Results and discussion. The most widespread method for the synthesis of 1,2-benzoxathiin-4(3H)-one 2,2-dioxides is the cyclization of salicylic acid derivatives. The known chemical transformations of 1,2-benzoxathiin-4(3H)-one 2,2-dioxides deal wit

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4

Lega, Dmitry A., Nikolay Yu Gorobets, Valentine P. Chernykh, Svetlana V. Shishkina, and Leonid A. Shemchuk. "Peculiarities of 2-amino-3-R-4-aryl-4H-pyranes multicomponent synthesis derived from 1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide." RSC Advances 6, no. 19 (2016): 16087–99. http://dx.doi.org/10.1039/c5ra24566d.

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The new 2-amino-3-R-4-aryl-6-ethyl-4,6-dihydropyrano[3,2-c][2,1] benzothiazine 5,5-dioxides were synthesized via three-component interaction of 1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide with arylcarbaldehydes and active methylene nitriles.

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5

Sundari, V., G. Nagarajan, S. Gurumurthy, and R. Valliappan. "Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide." E-Journal of Chemistry 6, no. 1 (2009): 177–82. http://dx.doi.org/10.1155/2009/254747.

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Synthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide andN-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4-methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant results

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6

Abu-El-Halawa, Rajab, Mohanad Masad, Yaser Bathich, et al. "Concise Synthesis and Displacement Reactions of Model 3-(Alkylthio)- 6-chloro- and 2,6-Dichlorothieno[2,3-e][1,4,2]dithiazine 1,1-Dioxides." Zeitschrift für Naturforschung B 66, no. 7 (2011): 715–20. http://dx.doi.org/10.1515/znb-2011-0712.

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A series of 3-(alkylthio)-6-chlorothieno[2,3-e][1,4,2]dithiazine 1,1-dioxides (7a - e) were prepared via interaction of deprotonated 2,5-dichlorothiophene-3-sulfonamide with carbon disulfide under reflux, followed by alkylation with alkyl halides. Employment of dimethyl sulfate afforded the isomeric 2-methyl-3-thione derivative 8 together with the expected 3-(methylthio) derivative 7a in a molar ratio of 1 : 4. Treatment of 7a or 10 with ethylamine, aniline or p-chloroaniline produced the corresponding N-ethyl- (or N-phenyl)-6-chlorothieno[2,3-e][1,4,2]dithiazine-3-amine 1,1-dioxides 3a - c. L

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7

Luo, Yong, Xiaolin Pan, Chen Chen, Liangqing Yao, and Jie Wu. "An unexpected reaction of 2-alkynylaryldiazonium tetrafluoroborate with sulfur dioxide." Chemical Communications 51, no. 1 (2015): 180–82. http://dx.doi.org/10.1039/c4cc07938h.

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An unexpected result from the reaction of 2-alkynylaryldiazonium tetrafluoroborate with sulfur dioxide is described. In the presence of morpholin-4-amine, this transformation catalyzed by copper(i) bromide proceeds through insertion of sulfur dioxide and intramolecular 5-endo cyclization, leading to benzo[b]thiophene 1,1-dioxides in moderate to good yields.

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8

Di Santo, R., R. Costi, M. Artico, et al. "1,2,5-Benzothiadiazepine and Pyrrolo[2,1-d]-[1,2,5]Benzothiadiazepine Derivatives with Specific Anti-Human Immunodeficiency Virus Type 1 Activity." Antiviral Chemistry and Chemotherapy 9, no. 2 (1998): 127–37. http://dx.doi.org/10.1177/095632029800900204.

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We synthesized and tested as novel inhibitors of human immunodeficiency virus type 1 (HIV-1) bi- and tricyclic thiadiazine ring homologues of 7-chloro-2-ethyl-2 H-1,2,4-benzothiadiazin-3-(4 H)-one 1,1-dioxide, which is a compound endowed with anti-HIV-1 activity at low micromolar concentrations. Benzothiadiazepine derivatives were obtained by alkylation of 8-chloro-2,3-dihydro-3-methyl-1,2,5-benzothiadiazepin-4(5 H)-one 1,1-dioxide, which was obtained by intramolecular cyclization of 2-(2-amino-5-chloro-benzenesulphonamido) propanoic acid. Pyrrolobenzothiadiazepines were synthesized from N-sub

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9

Cablewski, Teresa, Craig M. Forsyth, Craig L. Francis, Andris J. Liepa, and Victor Tran. "N,N-Dialkyl-N′-Chlorosulfonyl Chloroformamidines in Heterocyclic Synthesis. Part VII 4-Dialkylamino[1,2,3,5]Benzoxathiadiazepine Dioxides and 4-Dialkylamino-[2,1,3,5]Benzothiatriazepine Dioxides." Australian Journal of Chemistry 61, no. 10 (2008): 785. http://dx.doi.org/10.1071/ch08250.

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N,N-dialkyl-N′-chlorosulfonyl chloroformamidines 1 reacted with 2-aminophenols 2 to give 4-dialkylamino[1,2,3,5]benzoxathiadiazepine dioxides 3, which are examples of a new ring system. Reaction of 1 with 1,2-diaminobenzenes 7 afforded 4-dialkylamino[2,1,3,5]benzothiatriazepine dioxides 8 and 9, which are new derivatives of a rare ring system. Some N-alkyl and N-acyl derivatives of 3 and 8 were prepared to demonstrate the potential of these compounds as novel scaffolds for synthetic and medicinal chemistry.

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10

Ryan, Sarah J., Craig L. Francis, and G. Paul Savage. "Benzonitrile Oxide Cycloadditions with Exocyclic Methylene Benzothiazepine Dioxides." Australian Journal of Chemistry 67, no. 3 (2014): 381. http://dx.doi.org/10.1071/ch13444.

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N-substituted 5-methylene-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxides underwent 1,3-dipolar cycloaddition with benzonitrile oxide, generated in situ, to give isoxazoline spiro adducts. The cycloadditions were completely regioselective to give the hitherto unreported 3,4-dihydro-2H,4′H-spiro[benzo[f][1,2]thiazepine-5,5′-isoxazole] 1,1-dioxide cycloadduct. Where the N-substituent on the sulfonamide cycloaddition precursor was a 2-substituted arene, the resulting atropisomerism along the N-aryl bond led to facial selectivity in the cycloaddition reaction, with greater than 90 % diaster

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11

Rehse, Klaus, and Ulrich Müller. "New NO-Donors with Antithrombotic and Vasodilating Activities, Part 13: Pyrazol-4-one 1,2-Dioxides and 4-Hydroxyiminopyrazole 1,2-Dioxides." Archiv der Pharmazie 328, no. 11-12 (1995): 765–69. http://dx.doi.org/10.1002/ardp.19953281107.

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12

Listunov, Dymytrii, Kirill Popov, Yulian Volovenko, and Sergiy Popov. "Synthetic Modification of 1,3-Thiazolidin-4-One 1,1-Dioxides." Phosphorus, Sulfur, and Silicon and the Related Elements 188, no. 12 (2013): 1792–98. http://dx.doi.org/10.1080/10426507.2013.787998.

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13

REHSE, K., and U. MUELLER. "ChemInform Abstract: New NO-Donors with Antithrombotic and Vasodilating Activities. Part 13. Pyrazol-4-one 1,2-Dioxides and 4-Hydroxyiminopyrazole 1,2-Dioxides." ChemInform 27, no. 14 (2010): no. http://dx.doi.org/10.1002/chin.199614134.

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14

Cablewski, Teresa, Craig L. Francis, and Andris J. Liepa. "N, N-Dialkyl-N′-Chlorosulfonyl Chloroformamidines in Heterocyclic Synthesis. V The Preparation of some Benzimidazo-Fused [1,2,4,6]Thiatriazine Dioxides." Australian Journal of Chemistry 61, no. 1 (2008): 59. http://dx.doi.org/10.1071/ch07336.

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N,N-dialkyl-N′-chlorosulfonyl chloroformamidines 1 were treated with 2-aminobenzimidazoles 2 to give [1,2,4,6]thiatriazino[2,3-a]benzimidazole 1,1-dioxides 3 and [1,2,4,6]thiatriazino[4,3-a]benzimidazole 2,2-dioxides 4. Some N-alkyl-, N-acyl-, and N-sulfonyl-derivatives of 3 were prepared. These products are derivatives of rare heterocycles.

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15

Jongprateep, Oratai, and Rachata Puranasamriddhi. "Effects of Ageing Periods on Compositions and Sizes of Titanium Dioxide Particles Synthesized by Sol-Gel Technique." Key Engineering Materials 658 (July 2015): 185–89. http://dx.doi.org/10.4028/www.scientific.net/kem.658.185.

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Titanium dioxide has attracted worldwide attention due to its prominent photocatalytic activity. It is generally accepted that nanoparticulate titanium dioxide with pure anatase structure exhibits high reactivity. Sol-gel is a simple and cost-effective technique capable of synthesizing anatase-phase titanium dioxide with particle sizes in nanometer range. This research aimed at examining effects of ageing periods on compositions and sizes of titanium dioxide synthesized by sol-gel technique. Experimental results revealed that prolonged ageing period demoted formation of anatase phase. Pure ana

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16

Unterhalt, B., and C. Bensliman Bensliman. "Antiplatelet-Eigenschaften von 4-Oxo-4H-pyrazol-1,2-dioxiden." Scientia Pharmaceutica 69, no. 1 (2001): 21–26. http://dx.doi.org/10.3797/scipharm.aut-01-03.

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17

Riaño, Iker, Uxue Uria, Luisa Carrillo, Efraim Reyes, and Jose L. Vicario. "4-Alkenyl-5H-1,2,3-oxathiazole 2,2-dioxides in catalytic and enantioselective [4 + 2] cycloaddition through iminium activation. Straightforward access to the trans-decaline framework and to densely functionalized cyclohexanes." Organic Chemistry Frontiers 2, no. 3 (2015): 206–10. http://dx.doi.org/10.1039/c4qo00316k.

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18

Otto, Hans-Hartwig, and Herbert Plagge. "Synthesis and Reaction of 4-(a-Aminoarylidene)thiazetidine 1,1-Dioxides." HETEROCYCLES 35, no. 1 (1993): 193. http://dx.doi.org/10.3987/com-92-s6.

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19

NISHIYAMA, Takeo, and Hiromu KAMEOKA. "The Preparations of 1,2-Oxathiin-4(3H)-one 2,2-dioxides." NIPPON KAGAKU KAISHI, no. 7 (1993): 862–66. http://dx.doi.org/10.1246/nikkashi.1993.862.

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20

Cleator, Ed, Faye J. Sheen, Matthew M. Bio, K. M. Jos Brands, Antony J. Davies, and Ulf-H. Dolling. "Regioselective synthesis of N-substituted-4-substituted isothiazolidine-1,1-dioxides." Tetrahedron Letters 47, no. 25 (2006): 4245–48. http://dx.doi.org/10.1016/j.tetlet.2006.04.038.

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21

Kattenberg, J., E. R. de Waard, and H. O. Huisman. "Hydrobenzothiopyran-4-one S,S-dioxides. Synthesis and structural elucidation." Recueil des Travaux Chimiques des Pays-Bas 94, no. 5 (2010): 89–92. http://dx.doi.org/10.1002/recl.19750940502.

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22

GRUNDER-KLOTZ, E., P. HUMBERT, and J. D. EHRHARDT. "ChemInform Abstract: A Convenient Synthesis of 5-Substituted Tetrahydro-1,4,3-oxathiazine 4, 4-Dioxides." ChemInform 24, no. 30 (2010): no. http://dx.doi.org/10.1002/chin.199330199.

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23

Okumura, Yasuyuki, Koichi Mitsudo, and Seiji Suga. "Electrochemical Synthesis of Diarylsultones and Dibenzothiophene Dioxide Via C–O/C–S Bond Formation." ECS Meeting Abstracts MA2024-02, no. 53 (2024): 3637. https://doi.org/10.1149/ma2024-02533637mtgabs.

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Sultones and dibenzothiophene dioxides are widely used in the fields of pharmaceuticals, biologically active molecules, and material sciences [1][2]. While many synthetic methods have been reported, the synthesis of sultones and dibenzothiophene dioxides usually require stoichiometric amounts of oxidants, expensive transition metals, and harsh conditions. Therefore, the development of efficient and environmentally friendly methods for the synthesis of these compounds is in highly demand. Meanwhile, electrochemical reactions have received considerable attention as an environmentally benign meth

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24

Forsyth, Craig M., Craig L. Francis, Saba Jahangiri, Andris J. Liepa, Michael V. Perkins, and Anna P. Young. "N,N-Dialkyl-N'-Chlorosulfonyl Chloroformamidines in Heterocyclic Synthesis. Part VIII. Novel Pyrazolo-Fused Oxathiadiazines and Thiatriazoles." Australian Journal of Chemistry 63, no. 4 (2010): 659. http://dx.doi.org/10.1071/ch09581.

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N,N-dialkyl-N′-chlorosulfonyl chloroformamidines 1 reacted with pyrazol-3-ones 2 under a variety of conditions to give pyrazolo[2,3-e][1,2,3,5]oxathiadiazine dioxides 3 and pyrazolo[3,2-b][1,4,3,5]oxathiadiazine dioxides 5, and frequently, one or both of pyrazolo[1,2-b][1,2,3,5]thiatriazole 1,1,5-trioxides 4 and 1,1,7-trioxides 6. In all reactions, the pyrazolo[3,2-b][1,4,3,5]oxathiadiazine 5 was the major product, with the pyrazolo[2,3-e][1,2,3,5]oxathiadiazine 3 being a significant product in the absence of base. Prior to our recent work, the core ring systems of compounds 3 and 5 had not be

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25

Frolova, Svetlana G., Aleksey A. Vatlin, Dmitry A. Maslov, et al. "Novel Derivatives of Quinoxaline-2-carboxylic Acid 1,4-Dioxides as Antimycobacterial Agents: Mechanistic Studies and Therapeutic Potential." Pharmaceuticals 16, no. 11 (2023): 1565. http://dx.doi.org/10.3390/ph16111565.

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The World Health Organization (WHO) reports that tuberculosis (TB) is one of the top 10 leading causes of global mortality. The increasing incidence of multidrug-resistant TB highlights the urgent need for an intensified quest to discover innovative anti-TB medications In this study, we investigated four new derivatives from the quinoxaline-2-carboxylic acid 1,4-dioxide class. New 3-methylquinoxaline 1,4-dioxides with a variation in substituents at positions 2 and 6(7) were synthesized via nucleophilic aromatic substitution with amines and assessed against a Mycobacteria spp. Compound 4 showed

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26

Rozhenko, A. B., V. I. Slutskii, G. I. Khaskin, and E. G. Khil'chevskaya. "Acid hydrolysis of 2-iminoperhydrothieno[3, 4-d]-oxazol-5,5-dioxides." Chemistry of Heterocyclic Compounds 24, no. 10 (1988): 1189. http://dx.doi.org/10.1007/bf00475704.

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27

Unterhalt, B., and C. Bensliman. "ChemInform Abstract: Antiplatelet Qualities of 4-Oxo-4H-pyrazol-1,2-dioxides." ChemInform 32, no. 31 (2010): no. http://dx.doi.org/10.1002/chin.200131121.

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28

Geffken, Detlef, and Sabine Geisel. "Conversion ofN-arylglycolohydroxamic acids to 1,2,3-oxathiazolidin-4-one 2,2-dioxides." Journal of Heterocyclic Chemistry 31, no. 6 (1994): 1473–75. http://dx.doi.org/10.1002/jhet.5570310631.

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29

LEE, C. H., S. Y. JIN, C. Y. LEE, and B. Y. CHUNG. "ChemInform Abstract: Reactivity and Synthesis of 1,2,5-Thiadiazolidine 1,1-Dioxides: Synthesis of 4-Aryl-3-imino-1,2,5-thiadiazolidine 1,1-Dioxides." ChemInform 23, no. 22 (2010): no. http://dx.doi.org/10.1002/chin.199222159.

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30

Cristiano, M. Lurdes S., Amadeu F. Brigas, Robert A. W. Johnstone, Rui M. S. Loureiro, and Paula C. A. Pena. "Thermal Rearrangement of 3-Allyloxy-1,2-Benzisothiazole 1,1-Dioxides: An Unusual Inversion of Products of Sigmatropic [3,3]-Shift to Give the [1,3]-Isomers." Journal of Chemical Research 23, no. 12 (1999): 704–5. http://dx.doi.org/10.1177/174751989902301210.

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31

Zhu, Zhou-Hao, Meng-Lin Chen, and Guo-Fang Jiang. "Asymmetric synthesis of 4-aryl-1,2,5-thiadiazolidin-3-one 1,1-dioxides via Pd-catalyzed hydrogenation of cyclic ketimines." Organic & Biomolecular Chemistry 15, no. 6 (2017): 1325–28. http://dx.doi.org/10.1039/c6ob02655a.

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An efficient access to optically active sulfahydantoins, 4-aryl-1,2,5-thiadiazolidin-3-one 1,1-dioxides, was developed through palladium-catalyzed asymmetric hydrogenation of the corresponding cyclic N-sulfonylketimines with up to 98% ee.

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32

Mun, Dasom, Eunjin Kim, and Sung-Gon Kim. "Palladium-Catalyzed Decarboxylative [4+2] Cycloaddition of Vinyl Benzoxazinanones with Cyclic N-Sulfimines: Stereoselective Synthesis of Benzosulfamidate-Fused Tetrahydroquinazolines." Synthesis 51, no. 11 (2019): 2359–70. http://dx.doi.org/10.1055/s-0037-1610685.

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Methods for the catalytic synthesis of highly functionalized benzosulfamidate-fused tetrahydroquinazolines are presented. The decarboxylative [4+2] cycloaddition of vinyl benzoxazinanones with benzoxathiazine 2,2-dioxides catalyzed by Pd(PPh3)4 affords fused-tetrahydroquinazolines with high diastereoselectivities. Alternatively, catalytic asymmetric [4+2] cycloaddition employing a chiral palladium-containing phosphoramidite ligand provides optically enriched benzosulfamidate-fused tetrahydroquinazolines in good yields and with excellent diastereoselectivities and enantioselectivities.

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33

Potapov, Vladimir A., Svetlana V. Amosova, Irina V. Doron'kina, and Ol'ga V. Korsun. "A synthesis of 1-thia-4-chalcogenacyclohexane-1-oxides and 1,1-dioxides." Journal of Organometallic Chemistry 674, no. 1-2 (2003): 104–6. http://dx.doi.org/10.1016/s0022-328x(03)00180-3.

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34

BREUER, W., and H. J. FROHN. "ChemInform Abstract: Chemistry of Brominepentafluoride. Part 4. Arylbromine(V) Dioxides and Fluorideoxides." ChemInform 24, no. 15 (2010): no. http://dx.doi.org/10.1002/chin.199315154.

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35

Lee, Chai-Ho, Guo Fan Jin, Hyun Wha Lim, et al. "Facile synthesis of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides." Heteroatom Chemistry 22, no. 2 (2011): 192–97. http://dx.doi.org/10.1002/hc.20670.

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36

PLAGGE, H., та H. H. OTTO. "ChemInform Abstract: Synthesis and Reactions of 4-(α-Aminoarylidene)thiazetidine 1,1- Dioxides." ChemInform 24, № 28 (2010): no. http://dx.doi.org/10.1002/chin.199328177.

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37

Schapira, Celia B., and Isabel A. Perillo. "13C NMR Analysis of some 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxides." Journal of Heterocyclic Chemistry 30, no. 4 (1993): 1051–56. http://dx.doi.org/10.1002/jhet.5570300436.

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38

REDDY, D. B., M. M. REDDY, and G. V. SUBBARAJU. "ChemInform Abstract: Tetrahydro-1,4-thiazine-1,1-dioxides. Part 4. Synthesis and Conformational Analysis of Some 2,3,5-Trisubstituted Tetrahydro-1,4- thiazine-1,1-dioxides." ChemInform 26, no. 47 (2010): no. http://dx.doi.org/10.1002/chin.199547194.

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39

Renuga, S., S. Selvaraj, S. Perumal, A. Lycka, and M. Gnanadeebam. "Diastereoselective synthesis and1H and13C NMR study of 4-acetyl-2,6-diaroyl-3,5-diaryl-4-ethoxycarbonylthiane-1,1-dioxides." Magnetic Resonance in Chemistry 39, no. 10 (2001): 651–53. http://dx.doi.org/10.1002/mrc.897.

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40

Thangamani, A. "Synthesis and biological activities of some 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides." Journal of Applied and Advanced Research 1, no. 4 (2016): 8. http://dx.doi.org/10.21839/jaar.2016.v1i4.36.

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Some new 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides (6a-i) have been synthesized by reacting thiazine (4) with dimethyldioxirane (5) and tested for their antibacterial and acute toxicity studies. The synthesized compounds were characterized by elemental analysis, IR and NMR spectral data.

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41

Pátek, Marcel. "Titanium-mediated Dieckmann condensation." Collection of Czechoslovak Chemical Communications 55, no. 5 (1990): 1223–27. http://dx.doi.org/10.1135/cccc19901223.

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The Dieckmann condensation of alkyl 2-(N-methyl-N-(alkoxycarbonylmethyl)sulfamoyl)-benzoates Ia and Ib with titanium tetrachloride-tert-amine or butyltitanium ate complex III affords alkyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxides IIa and IIb which are the piroxicam intermediates.

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42

Goya, Pilar, and Ana Martinez. "N-Glucosyl-5-amino-4-carbamoyl- and 4-Ethoxycarbonylimidazoles as Potential Precursors of 4-Oxoimdazo[4,5-c]-1,2,6-thiadiazine 2,2-Dioxides." HETEROCYCLES 24, no. 12 (1986): 3451. http://dx.doi.org/10.3987/r-1986-12-3451.

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43

Michael, Jeffrey Daniel. "Preparation of 4-Substituted 3,5-Diaryloxy and 3,5-Diamino-1,2,4,6-Thiatriazine 1,1-Dioxides." Synthesis 1987, no. 02 (1987): 170–73. http://dx.doi.org/10.1055/s-1987-27876.

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44

Agejas, Javier, Jose L. Garcı́a-Navı́o, and Carlos Lamas. "A straightforward synthesis of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides." Tetrahedron Letters 41, no. 50 (2000): 9819–23. http://dx.doi.org/10.1016/s0040-4039(00)01778-0.

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45

Dyachenko, Maksim S., Alexey V. Dobrydnev та Yulian M. Volovenko. "4-Amino-2,3-dihydro-1λ6-isothiazole-1,1-dioxides and their chemical properties evaluation". Molecular Diversity 22, № 4 (2018): 919–27. http://dx.doi.org/10.1007/s11030-018-9848-x.

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46

Shundrin, L. A., I. G. Irtegova, A. D. Rogachev, and V. A. Reznikov. "Molecular ions of 3,3′-bi(2-R-5,5-dimethyl-4-oxopyrrolinylidene) 1,1′-dioxides." Russian Chemical Bulletin 54, no. 5 (2005): 1178–84. http://dx.doi.org/10.1007/s11172-005-0377-2.

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47

Moiseev, A. M., E. S. Balenkova, and V. G. Nenajdenko. "[6+4] Cycloaddition reactions of acceptor thiophene dioxides: The synthesis of substituted azulenes." Russian Chemical Bulletin 55, no. 1 (2006): 141–46. http://dx.doi.org/10.1007/s11172-006-0227-x.

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48

Porcs‐Makkay, Márta, Imre Gyűjtő, Gyula Lukács, et al. "Synthesis, Alkylation and Reduction of 4‐Aryl‐2 H ‐1,2,3‐benzothiadiazine 1,1‐dioxides." ChemistrySelect 4, no. 28 (2019): 8295–300. http://dx.doi.org/10.1002/slct.201901212.

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49

Müller, Martin, та Hans-Hartwig Otto. "Properties and Reactions of Substituted 1,2-Thiazetidine 1,1-Dioxides: 4-Alkylidene-β-sultams". Liebigs Annalen der Chemie 1992, № 7 (1992): 687–92. http://dx.doi.org/10.1002/jlac.1992199201116.

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50

Charlton, James L. "Diastereoselectivity and asymmetric induction in the Diels–Alder reaction of o-quinodimethanes." Canadian Journal of Chemistry 64, no. 4 (1986): 720–25. http://dx.doi.org/10.1139/v86-116.

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Abstract:

The extent of asymmetric induction in the bimolecular Diels–Alder reactions of chiral o-quinodimethanes with dimethyl fumarate, methyl acrylate, and maleic anhydride has been studied. o-Quinodimethanes with chiral α-alkoxy groups were prepared from 1-alkoxy-1,3-dihydrobenzo[c]thiophene-2,2-dioxides 4a–f or 1-alkoxy-3-phenyl-1,3-dihydrobenzo[c]thiophene-2,2-dioxides 4g–h by thermolysis. These alkoxybenzosulfones were prepared from the corresponding hydroxybenzosulfones 8 and 1-phenylethanol, 2-phenyl-1-propanol, 4-phenyl-2-butanol, 1-phenyl-2-propanol, 3,3-dimethyl-2-butanol, or 1-cyclo-hexylet

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