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Journal articles on the topic '42 to 45.8(Category II)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Ulyanov, M. V., and M. I. Fomichev. "Research of Features of the Combined Algorithm for Solving the Asymmetric Traveling Salesman Problem." INFORMACIONNYE TEHNOLOGII 27, no. 1 (2021): 3–8. http://dx.doi.org/10.17587/it.27.3-8.

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The exact algorithm that implements the Branch and Boimd method with precomputed tour which is calculated by Lin-Kernighan-Helsgaun metaheuristic algorithm for solving the Traveling Salesman Problem is concerned here. Reducing the number of decision tree nodes, which are created by the Branches and Bound method, due to a "good" precomputed tour leads to the classical balancing dilemma of time costs. A tour that is close to optimal one takes time, even when the Lin-Kernighan-Helsgaun algorithm is used, however it reduces the working time of the Branch and Bound method. The problem of determinin

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Abdi, Tenri Risna. "Karakteristik Pasien Hipertensi di Puskesmas Tabaringan Makassar." Indonesian Journal of Health 1, no. 02 (2021): 112–19. http://dx.doi.org/10.33368/inajoh.v1i02.24.

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Hypertension is a condition in which systolic blood pressure (TDS) ≥ 140 mmHg or diastolic blood pressure (TDD) ≥ 90 mmHg that measured by health personnel at least two times. The research objective is to describe the characteristics of hypertensive patients at Tabaringan Health Center. The characteristics referred to gender,age, BMI, and hypertension degree. This research used a descriptive research method by using an observational approach to describe the characteristics of hypertensive patients. The results showed that the total number of male patients with hypertension was 34 (44.7%) and f

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Tanjung, Asbar, Ika Nurhidayah, Sharfina Maulidayanti, and Ing Mayfa Br Situmorang. "Analysis of Serum Creatinine Levels, Blood Pressure and Grade of Hypertension of Chronic Disease Management Program Participants." Medical Laboratory Technology Journal 10, no. 2 (2025): 143–51. https://doi.org/10.31964/mltj.v10i2.619.

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Indonesia is one of the countries with the highest number of cases of hypertension in the world; the predominant patient is the elderly. In some patients with hypertension, increased blood pressure causes impaired salt and creatinine excretion, resulting in poor kidney function. A chronic disease management program is a health care system with a proactive-integrative approach to prevent further complications. The research objective is to analyze serum creatinine levels, blood pressure, and hypertension grade and determine the relationship between serum creatinine and blood pressure in chronic

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Kroeger, Nicolaus, Tatjana Zabelina, Thomas Binder, et al. "Comparable Results of HLA-Mismatched Vs HLA-Matched Unrelated Donors for Allogeneic Stem Cell Transplantation Using Pre-Transplant ATG." Blood 112, no. 11 (2008): 966. http://dx.doi.org/10.1182/blood.v112.11.966.966.

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Abstract For patients lacking an HLA-identical sibling, more than ten million unrelated donor (UD) are available for donation of hematopoietic stem cells. Despite this increasing number of UD, up to 30 % of the patients will not find a completely-HLA-matched donor. HLAmismatched unrelated stem cell transplantation (SCT) is associated with an increased risk of acute and chronic graft-versus-host disease and a higher transplant-related mortality resulting in a lower survival after allogeneic SCT. We analyzed on outcome of allele- and antigen-mismatch SCT from UD using pre-transplantation anti-th

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Mudib, Mudib, Kristanto Yuli Yarso, and Henky Agung Nugroho. "Age as an Independent Factor in the Permanent Chemotherapy-Induced Amenorrhea Incidence in Breast Cancer Patients at Dr. Moewardi Hospital, Surakarta, Indonesia." Open Access Macedonian Journal of Medical Sciences 9, B (2021): 816–20. http://dx.doi.org/10.3889/oamjms.2021.6712.

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Background: Chemotherapy Induced Amenorrhea (CIA) is one common side effect of chemotherapy in breast cancer patients. Some who have CIA may experience menstruation return while others experience permanent CIA. Aim: to examines the factors that contribute to the incidence of persistent CIA in breast cancer patients. Methods: The population of this retrospective study was new breast cancer patients with premenopausal status when they started receiving chemotherapy at dr Moewardi Hospital Surakarta, Indonesia, from January 2019 to July 2021. To determine the relationship, the chi-squ

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Mark, Tomer M., Sujitha Yadlapati, Lyubov Neglyad, et al. "High-Dose Carfilzomib and Dexamethasone As First-Line Treatment in Symptomatic Multiple Myeloma." Blood 126, no. 23 (2015): 4258. http://dx.doi.org/10.1182/blood.v126.23.4258.4258.

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Abstract Background: Carfilzomib (Cfz) is approved for use in relapsed and refractory multiple myeloma (RRMM) at a dose of 27mg/m2 after escalation from 20mg/m2. The response rate for Cfz and dexamethasone (dex) as first-line therapy in multiple myeloma (MM) is unknown. Higher doses of Cfz have been shown to enhance overall response in RRMM (Lendvai 2014); the presence of a dose-response relationship of Cfz for first-line therapy in untreated MM has not been evaluated. A protocol of Cfz-Dex induction at two dosing levels, followed by BiRd (Clarithromycin 500mg PO BID, Lenalidomide (Len) 25mg f

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Halverson, David, Miriam E. Mossoba, Seth M. Steinberg, et al. "Pre-Emptive T-Rapa Cell DLI for Therapy of High-Risk Lymphoma After Low-Intensity Allogeneic HCT." Blood 120, no. 21 (2012): 471. http://dx.doi.org/10.1182/blood.v120.21.471.471.

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Abstract Abstract 471 Lymphoma progression remains an obstacle after allogeneic HCT, particularly after non-myeloablative conditioning in patients with high-risk histology (non-indolent; Kahl et al; Blood, 2007) and chemotherapy refractory disease (Bishop et al; Cancer, 2010). In murine models, rapamycin-resistant T cells favorably modulated the balance between GVHD, graft rejection, and GVT effects. To translate this, we conducted a multi-center phase II trial (NCT0074490) of T-Rapa cells infused as a pre-emptive DLI after low-intensity allogeneic HCT; here, we report overall outcome of patie

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Nestler, Tim, Justine Schoch, Viola Düring, et al. "Influence of MRIs performed in a 6-week interval on the histopathological detection of prostate cancer with different PIRADS classifications: A real-world data analysis." Journal of Clinical Oncology 43, no. 5_suppl (2025): 334. https://doi.org/10.1200/jco.2025.43.5_suppl.334.

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334 Background: In the early phases of MRI-guided prostate biopsies, it was often necessary to perform an additional in-house multiparametric MRI after an external MRI to accurately assess lesions for biopsy. This study aims to evaluate the consistency of lesion identification and the associated clinical and histological outcomes at a high-volume tertiary care center performing over 500 biopsies annually. Methods: This analysis included real-world data from 111 patients treated between 2018 and 2022. Each patient underwent two multiparametric MRI scans of the prostate at different institutions

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Patch, David A., James T. McMurtrie, Mason Frazier, et al. "Union Rates of Talar Neck Fractures with Critical Bone Defects Treated with Autograft." Foot & Ankle Orthopaedics 7, no. 1 (2022): 2473011421S0039. http://dx.doi.org/10.1177/2473011421s00392.

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Category: Trauma Introduction/Purpose: The purpose of this study was to evaluate union of talar neck fractures with critical bone defects treated acutely with autologous tibial bone graft during primary osteosynthesis. We hypothesized that acute autografting leads to reliable union rates. Methods: A case series at a Level I trauma center was performed to identify patients who underwent open reduction and internal fixation of talar neck fracture with proximal tibial autograft between 2015 and 2018. Inclusion criteria were age greater than 18 years and displaced talar neck fracture with critical

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Lugtenburg, Pieternella J., Josée M. Zijlstra, Jeanette K. Doorduijn, et al. "Rituximab-PECC Induction Followed by 90y-Ibritumomab Tiuxetan Consolidation in Relapsed or Refractory DLBCL Patients Who Are Not Eligible for or After ASCT: Preliminary Results From a Phase II HOVON Study." Blood 120, no. 21 (2012): 2729. http://dx.doi.org/10.1182/blood.v120.21.2729.2729.

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Abstract Abstract 2729 Background. Patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) after- or not eligible for autologous stem cell transplantation (ASCT) have a poor prognosis. The optimum salvage therapy for these patients is not known. Treatment results with second-line chemotherapy have generally been disappointing. In some centers in the Netherlands PECC (Prednisone, Etoposide, Chlorambucil and Lomustine) combination chemotherapy is used as salvage treatment for such patients. PECC is a completely oral schedule. The efficacy and toxicity of PECC in this patient c

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Lim, Jung-Won, and Hong-Geun Jung. "The Radiographic Support for Distal Tibia Medial Opening-Wedge Osteotomy with Fibular Valgization Osteotomy for Medial Ankle Osteoarthritis." Foot & Ankle Orthopaedics 5, no. 4 (2020): 2473011420S0033. http://dx.doi.org/10.1177/2473011420s00332.

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Category: Ankle; Ankle Arthritis Introduction/Purpose: Supramalleolar osteotomy (SMO) has recently been accepted as the major surgical option for treating painful asymmetric ankle arthritis. The effectivenss of additional fibular valgization osteotomy during SMO procedure is still controversial. This study aimed to evaluate radiological and clinical outcomes of medial compartment ankle osteoarthritis (OA) after SMO with fibular valgization osteotomy. Also, the study is aimed to describe the radiographic support for the SMO with additional fibular osteotomy in relieving the medial ankle pain. M

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Вавин, В. В., И. И. Нажмудинов, Б. Х. Давудова, К. М. Магомедова, and Х. Ш. Давудов. "Surgical Treatment of Chronic Cicatricial Stenosis of the Vestibular Larynx." Оториноларингология. Восточная Европа 14, no. 2 (2024): 192–202. http://dx.doi.org/10.34883/pi.2024.14.2.031.

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Введение. Проблема хронического рубцового стеноза гортани и трахеи актуальна в связи с сохраняющимся большим числом пациентов с данной патологией. Многочисленные работы, посвященные стенозу гортани и трахеи, в большинстве случаев посвящены поражению подскладочного и голосового отделов гортани. При этом стеноз вестибулярного отдела считается достаточно редким полиэтиологичным заболеванием, требующим детального изучения. Цель. Провести анализ клинических случаев и результатов лечения пациентов с хроническим рубцовым стенозом вестибулярного отдела гортани для выявления закономерностей течения заб

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Gisslinger, Heinz, Veronika Buxhofer-Ausch, Josef Thaler, et al. "Efficacy and Safety Of AOP2014/P1101, a Novel, Investigational Mono-Pegylated Proline-Interferon Alpha-2b, In Patients With Polycythemia Vera (PV): Update On 51 Patients From The Ongoing Phase I/II Peginvera Study." Blood 122, no. 21 (2013): 4046. http://dx.doi.org/10.1182/blood.v122.21.4046.4046.

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Abstract Background AOP2014/P1101 is a novel, investigational mono-pegylated proline-interferon alpha-2b. In contrast to other pegylated IFNs, AOP2014/P1101 consists of one predominant isoform. AOP2014/P1101 has Orphan Drug Designation in EU and USA for treatment of patients with PV. Study design Long term efficacy and safety data are being collected in the follow-up extension stage of the study (collecting the data of both Phase I and Phase II portions of the study), after the maximum tolerated dose (MTD) of AOP2014, administered subcutaneously every 14 days, has been defined earlier. Patient

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Miletic, Marija, Razia Aslam, Catey Bunce, et al. "Therapeutic approaches and outcomes in patients aged 50+ with germ cell tumours." Journal of Clinical Oncology 43, no. 5_suppl (2025): 636. https://doi.org/10.1200/jco.2025.43.5_suppl.636.

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636 Background: Testicular germ cell tumours (GCT) are the most common malignancy in young men, mainly in their 30s. While multimodal treatment leads to excellent survival in younger patients (pts), its incidence is rising in men over 50, who often have comorbidities and higher risks of chemotherapy (ChT) toxicity. Limited data on outcomes in this group highlights the need for more research. Methods: We conducted a retrospective single centre study, analysing pts diagnosed with GCT aged 50 years or older between 2014 -2023. Results: 142 pts were analysed, median age of 57 years (range 50–83).

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Müller, Martin C., Jorge Cortes, Dong-Wook Kim, et al. "Dasatinib Efficacy in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) and Pre-Existing BCR-ABL Mutations." Blood 112, no. 11 (2008): 449. http://dx.doi.org/10.1182/blood.v112.11.449.449.

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Abstract Dasatinib (SPRYCEL®) is an effective BCR-ABL inhibitor that is 325-fold more potent than imatinib and 16-fold more potent than nilotinib in vitro against unmutated BCR-ABL. Across a series of phase II and III trials, dasatinib has demonstrated durable efficacy in patients with CML following resistance, suboptimal response, or intolerance to imatinib. BCR-ABL mutations are an important cause of imatinib failure and suboptimal response. Here, the efficacy of dasatinib in patients with CML-CP who had baseline BCR-ABL mutations following imatinib treatment was analyzed using data from thr

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Evens, Andrew M., Chadi Nabhan, Irene Helenowski, et al. "Multicenter Analysis of 150 Very Elderly Non-Hodgkin's Lymphoma (NHL) Patients: Impact of Comorbidities and Response to Initial Therapy on Survival." Blood 116, no. 21 (2010): 3124. http://dx.doi.org/10.1182/blood.v116.21.3124.3124.

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Abstract Abstract 3124 Background: The incidence of NHL increases exponentially with rising age. The most rapidly growing segment of the population is persons > age 65 years, especially > age 80. As a percentage of US population, the age group >80 years has increased by >250% from 1960 to 2000. Furthermore, persons >80 years will more than double within 20 years. However, little data is available regarding the characteristics or outcomes of very elderly NHL patients (pts). Methods: We completed a multicenter retrospective analysis of very elderly NHL pts (=/> 80) diagnosed (d

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Paviglianiti, Annalisa, Marta Bellver Sanchis, Marta Peña, et al. "Pre-Transplant Diabetes Is Associated with Increased Risk of Relapse after HCT: A Single Center Experience." Blood 144, Supplement 1 (2024): 7412. https://doi.org/10.1182/blood-2024-198124.

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Background: Evaluating nutritional status at allogeneic hematopoietic cell transplantation (HCT) is of outmost importance. Moreover, obesity and diabetes mellitus (DM) can modulate immune response, which may impact HCT outcomes. Methods: We retrospectively analyzed 158 patients who underwent HCT in a single center between January 2020 and June 2023. Nutritional status was assessed by Nutritional Risk Index (NRI) and Patient-Generated Subjective Global Assessment (PG-SGA). BMI (usual, pre-HCT and at discharge), previous diagnosis of DM and biochemical parameters were additionally collected. Res

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Lestari, Putri Indah Dwi, Novi Wahyu Hidayati, and Hastiani Hastiani. "INFORMATION SERVICES USING THE CAPCUT APPLICATION FOR CLASS IX STUDENTS AT SMPN 22 PONTIANAK." ROMEO REVIEW OF MULTIDISCIPLINARY EDUCATION, CULTURE AND PEDAGOGY 3, no. 4 (2024): 252–65. http://dx.doi.org/10.55047/romeo.v3i4.1349.

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This research aims to improve understanding of advanced study planning through information services using the CapCut application for class IX C students at SMPN 22 Pontianak. The method used is class action with two cycles. The research results demonstrate that students' talents and interests increased from 41% to 55% after the first action cycle and to 81% after the second cycle. Understanding secondary school improved from 42% in the poor category to 52% in the sufficient category after the first cycle of action. Following the second cycle, it further increased to 86% in the good category. T

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Dwi Lestari, Putri Indah, Novi Wahyu Hidayati, and Hastiani Hastiani. "Increasing Junior High School Students' Career Understanding Through CapCut Media-Assisted Orientation Services." ROMEO REVIEW OF MULTIDISCIPLINARY EDUCATION CULTURE AND PEDAGOGY 4, no. 1 (2024): 39–50. https://doi.org/10.55047/romeo.v4i1.1418.

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This research aims to improve understanding of advanced study planning through information services using the CapCut application for class IX C students at 22 Junior High School Pontianak. The method used is class action with two cycles. The research results demonstrate that students' talents and interests increased from 41% to 55% after the first action cycle and to 81% after the second cycle. Understanding secondary school improved from 42% in the poor category to 52% in the sufficient category after the first cycle of action. Following the second cycle, it further increased to 86% in the go

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HASSAN, SAMIA, MISBAH KAUSAR JAVAID, and SADIA TARIQ. "EMERGENCY CAESAREAN SECTION." Professional Medical Journal 15, no. 02 (2008): 211–15. http://dx.doi.org/10.29309/tpmj/2008.15.02.2772.

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Objective: Comparative analysis of problems encountered betweenpatients of elective caesarean section and patients for whom elective caesarean section was planned but ended upin emergency caesarean section. Design: Descriptive prospective analysis. Setting: Gynae Unit-II, Services Hospital,Lahore. Duration: One year, 1 January 2006 to 31 December 2006. Patients & Methods: A prospective study of st st100 patients who presented for antenatal care (ANC) and for whom elective caesarean section (CS) was planned wasdone. Patients evaluation was done on a designed performa that included demograph

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Musin, Sh I., A. V. Sultanbaev, K. V. Menshikov, et al. "Oropharyngeal cancer diagnosis and treatment in actual clinical practice in the Republic of Bashkortostan: analysis for 2020." Creative surgery and oncology 12, no. 4 (2023): 267–74. http://dx.doi.org/10.24060/2076-3093-2022-12-4-267-274.

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Introduction. Th e growing incidence of oropharyngeal cancer is driven by an increase in frequency of HPV-associated oropharyngeal cancer. Th e morbidity pattern of oropharyngeal cancer is area-specific.Aim. To analyze the oropharyngeal cancer diagnosis and treatment in the Republic of Bashkortostan for 2020.Materials and methods. Th e authors carried out a 2020 retrospective analysis of the diagnosis and treatment results of patients with oropharyngeal cancer. 79 patients were identified with this diagnosis. 84.8% (67/79) among them were males and 15.2% females (12/79). Th e mean age of the p

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Murias, Juan M., Matthew D. Spencer, John M. Kowalchuk, and Donald H. Paterson. "Influence of phase I duration on phase II V̇o2 kinetics parameter estimates in older and young adults." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 301, no. 1 (2011): R218—R224. http://dx.doi.org/10.1152/ajpregu.00060.2011.

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Older adults (O) may have a longer phase I pulmonary O2 uptake kinetics (V̇o2p) than young adults (Y); this may affect parameter estimates of phase II V̇o2p. Therefore, we sought to: 1) experimentally estimate the duration of phase I V̇o2p (EE phase I) in O and Y subjects during moderate-intensity exercise transitions; 2) examine the effects of selected phase I durations (i.e., different start times for modeling phase II) on parameter estimates of the phase II V̇o2p response; and 3) thereby determine whether slower phase II kinetics in O subjects represent a physiological difference or a by-pr

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Wymond, Brooke S., Kacie M. Dickinson, and Malcolm D. Riley. "Alcoholic beverage intake throughout the week and contribution to dietary energy intake in Australian adults." Public Health Nutrition 19, no. 14 (2016): 2592–602. http://dx.doi.org/10.1017/s136898001600063x.

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AbstractObjectiveTo assess alcoholic beverage intake among Australian adults and its contribution to dietary energy intake.DesignSecondary analysis of a national dietary survey using 24 h dietary recall.SettingAustralian National Nutrition and Physical Activity Survey (NNPAS) conducted from May 2011 to June 2012.SubjectsAdults (n9341) aged 19 years and over.ResultsOn the day preceding the survey, 32·8% of Australian adults consumed one or more alcoholic drinks. The median contribution to total energy intake for consumers did not differ significantly between males and females (13·7% and 12·9%,

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Kijowski, Jacek, and Emilia Kupińska. "Induction of DPM Changes in Broiler Chickens and Characteristics of Myopathy Symptoms." Bulletin of the Veterinary Institute in Pulawy 56, no. 2 (2012): 217–23. http://dx.doi.org/10.2478/v10213-012-0039-8.

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Abstract The aim of the study was to induce deep pectoral myopathy (DPM) lesions in 42 to 45-day-old broiler chickens of the Ross 308 and Flex genetic lines, kept under standard intensive breeding management conditions applied in Poland, and to assess the degree of myopathy. A total of 110 and 120 carcasses, respectively, were examined. The study method consisted of the exposure of the birds to a stress factor (forced wing flapping) at specific time intervals prior to slaughter and at different durations of the stress factor. As a result of the conducted experiment, DPM symptoms appeared in th

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Tuzzahrah, Maura, Erikavitri Yulianti, and Lilik Djuari. "Profile of Parenting Style in University Students with Tendency of Hedonism Lifestyle." JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga 10, no. 1 (2019): 29. http://dx.doi.org/10.20473/juxta.v10i12019.29-33.

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A B S T R A C TIntroduction: This research is to determine the profile of parenting style with tendency of hedonism lifestyle in university students of Medicine Program Faculty Of Medicine Airlangga University Batch 2015.Methods: This study is a observational analytic research with cross-sectional time and used questionnare as research instrument given to 200 respondentsResults: : 16 university students raised with authoritarian parenting style (8.30%), 169 students raised with authoritative parenting style (87.56%), and 8 students raised with permissive parenting style (4.14%). Students with

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Salazar Mun'oz, B. A. "Use of negative pressure in the treatment of anaerobic non-clostridial perineal infection." Wounds and wound infections. The prof. B.M. Kostyuchenok journal 8, no. 3 (2021): 44–47. http://dx.doi.org/10.25199/2408-9613-2021-8-3-42-45.

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The article presents a clinical case of a successful complex treatment anaerobic non-clostridial perineal infection in a 54-year-old patient with long-term diabetes mellitus. Particular attention is paid to the possibilities of local treatment using negative pressure wound therapy in the management of this patients category.

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Shah, Mithun V., Monika Kutyna, Syed Shah, et al. "Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53-Mutations Using an Independent International Cohort." Blood 142, Supplement 1 (2023): 3243. http://dx.doi.org/10.1182/blood-2023-187860.

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BACKGROUND: Recently proposed World Health Organization (WHO, 5 th edition) and International Consensus Classification (ICC) recognized myeloid neoplasms (MN) harboring TP53-mutated ( TP53mut) as a separate entity. However, there are critical differences between the two classifications regarding allelic-status, variance allele frequency (VAF) cut-off and blast categories, that may lead to under- or overestimation of the risk. METHODS: We analyzed MN harboring TP53mut (VAF ≥2%, n=536) managed at Mayo Clinic (USA) and South Australia Health Network (Australia). ICC (Arber et al, Blood 2022) and

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Reece, D. E., V. Sanchorawala, U. Hegenbart, et al. "Phase I/II study of bortezomib (B) in patients with systemic AL-amyloidosis (AL)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 8050. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.8050.

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8050 Background: AL is characterized by deposition of monoclonal immunoglobulin light chains leading to multi-organ failure and death. B (Velcade®) is a specific inhibitor of the 26S proteasome with activity in several malignancies. This mechanism of action raises concern of enhancing the amyloidogenic protein deposition and worsening of AL. This phase I/II study is to determine the maximum tolerated dose (MTD) and toxicity profile of B in pts previously treated for AL. Secondary objectives include the rate and duration of hematologic and organ responses. Methods: A 3+3 dose escalation design

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Aman, Kishor, Kumar Jwala, Ranjan Shrivastava Manish, and Anwar Zaman Zaki. "A Comparative Study of the Efficacy and Safety of 5% Minoxidil and 1 Mg Finasteride in Male Androgenetic Alopecia Patients at a Tertiary Centre in Bihar." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 1982–88. https://doi.org/10.5281/zenodo.12607392.

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<strong>Background: </strong>Androgenetic alopecia (AGA) is responsible for 95% of hair loss in males over 50. However, AGA is far less frequent in women, with around 40% of women experiencing some degree of hair loss, particularly after menopause. In a gradual process, alopecia is caused by the 5-reductase enzyme converting testosterone to dihydrotestosterone (DHT), which causes hair follicles to shrink. <strong>Aims and Objectives: </strong>A comparative study of the efficacy and safety of 5% minoxidil and 1 mg finasteride in male androgenetic alopecia patients. <strong>M

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A. Nischal Prasad and Nand Kumar B. Madhekar. "Tamsulosin and Tadalafil in Relieving Benign Prostatic Hyperplasia Related Symptoms- A Comparative Study." Academia Journal of Surgery 3, no. 1 (2020): 80–83. http://dx.doi.org/10.47008/ajs/2020.3.1.17.

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Background: Benign prostatic hyperplasia (BPH) is the most common neoplastic condition afflicting men and constitutes a major factor impact- ing the health of the male. The present study compared tamsulosin and tadalafil in relieving benign prostatic hyperplasia related symptoms in patients. Subjects and Methods: The present study was conducted at NRI Medical College & Hospital, Chinakakani, Mangalagiri Mandal, Andhra Pradesh from April 2007 to March 2008 on 82 men of >45 years of age with LUTS secondary to benign prostatic hyperplasia (BPH) with an IPSS >8. All patients were divided

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Karp, Judith E., B. Douglas Smith, Jacqueline Greer, et al. "Phase II Clinical Trial of Flavopiridol (FL) Followed by ara-c and Mitoxantrone (AM) for Adults with Relapsed and Refractory Acute Leukemias." Blood 106, no. 11 (2005): 2784. http://dx.doi.org/10.1182/blood.v106.11.2784.2784.

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Abstract The cell cycle inhibitor FL targets cyclin-dependent kinases, induces checkpoint arrest and interrupts transcriptional elongation. We demonstrated in an in vitro model that F causes apoptosis in leukemic blasts and increases A cytotoxicity in remaining blasts (Clin Cancer Res9: 307–315, 2003). Based on these observations, we have conducted a Phase II trial of timed sequential therapy (TST) with FL 50 mg/m2 daily x 3 days followed by A 2 gm/m2/72 hr infusion beginning day 6 and M 40 mg/m2 day 9 (FLAM). A total of 42 adults (median age 50, range 23–75) received FLAM for acute myelogenou

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Natalina, Riny, and Legawati Legawati. "PEMBERIAN DAN DEMONSTRASI PENGOLAHAN JUS BAYAM MERAH UNTUK IBU HAMIL TRIMESTER I DAN II DENGAN ANEMIA DI PUSKESMAS BUKIT RAWI." EJOIN : Jurnal Pengabdian Masyarakat 2, no. 1 (2024): 74–78. http://dx.doi.org/10.55681/ejoin.v2i1.2168.

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Anemia is caused due to iron deficiency caused by physiological changes due to pregnancy that are aggravated by a state of lack of nutrients, vitamin B12, folic acid and vitamin C. The goal is to increase the ability of pregnant women in making red spinach juice and increase HB levels of third trimester pregnant women with anemia with consumption of red spinach juice. Method of activity: Pregnant women involved a total of 20 pregnant women and previously checked the Hb levels of pregnant women before being given red spinach juice, followed by a demo of making red spinach juice. After 14 days,

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Barbhaiya, M., D. Erkan, Y. Ahmadzadeh, K. Costenbader, R. Naden, and S. Zuily. "OP0097 DEVELOPMENT OF NEW INTERNATIONAL CLASSIFICATION CRITERIA FOR ANTIPHOSPHOLIPID SYNDROME: PHASE III CASE COLLECTION RESULTS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 64.2–64. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5294.

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Background:An international multi-disciplinary effort is underway to develop rigorous, new, consensus- and evidence-based classification criteria for Antiphospholipid Syndrome (APS). The methodological approach includes four phases; we have previously presented phases I and II (item generation and reduction), which resulted in 27 candidate criteria1organized in laboratory and clinical domains.Objectives:Phase III (item weighting/threshold identification) is currently underway; here we report initial Phase III case collection results.Methods:We used REDCap, a secure data system, for Phase III i

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Lê, Quang Đạo, Minh Dương Vũ, Bá Ngọc Nguyễn та Việt Anh Lê. "ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ KHÔNG PHẪU THUẬT Ở BỆNH NHÂN BONG GÂN KHỚP CỔ CHÂN TẠI BỆNH VIỆN DÃ CHIẾN CẤP 2 VIỆT NAM - NAM XU ĐĂNG". VietNam Military Medical Unisversity 47, № 9 (2022): 131–39. http://dx.doi.org/10.56535/jmpm.v47i9.219.

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Đặt vấn đề: Bong gân khớp cổ chân là tình trạng tổn thương phức hợp dây chằng bên của khớp cổ chân. Tổn thương được điều trị bằng cách bất động; điều trị không phẫu thuật và can thiệp phẫu thuật. Bong gân khớp cổ chân chiếm tỷ lệ cao trong số các mặt bệnh chấn thương điều trị tại Bệnh viện Dã chiến cấp 2 Việt Nam. Mục tiêu: Đánh giá hiệu quả của điều trị không phẫu thuật trong xử trí bong gân khớp cổ chân. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang không đối chứng trên 42 bệnh nhân (BN) được điều trị tại Bệnh viện Dã chiến cấp 2 Việt Nam tại Bentiu, Nam Xu Đăng với chẩn đoán bong gân

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Sumiyati, Sumiyati. "Efforts to Increase Activities and Learning Outcomes Through Macromedia Fash 8 Collaboration and Flash Cards for Class II Semester I Students at SDN Pulorejo 02 Academic Year 2022/2023." Al Hikmah: Journal of Education 3, no. 2 (2022): 241–60. http://dx.doi.org/10.54168/ahje.v3i2.129.

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The aims of this study are: 1) To describe the PAI learning process through the collaboration of Macromedia Fash 8 and Flash Card, 2) To find out whether the application of the collaboration of Macromedia Fash 8 and Flash Card can improve student learning activities, 3) To find out whether the application of MacromediaFash 8 and Flash Cards can improve learning outcomes for Class II SDN Pulorejo 02. This classroom action research uses a qualitative descriptive method. The subject of the research is the second semester of the first semester of the 2022/2023 academic year at SD Negeri Pulorejo 0

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Zhao, Yangzhi, Wei Guo, Jia Li, et al. "A Retrospective Analysis on the Efficacy and Saftey of Obinutuzumab in the Treatment of Non-Hodgkin B Cell Lymphoma." Blood 142, Supplement 1 (2023): 4427. http://dx.doi.org/10.1182/blood-2023-187801.

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Backgroud: Obinutuzumab was approved by China's Drug Administration in June 2021, and there have been few real-world reports about efficacy and safety. Objective:Analysis the efficacy and safety of Obinutuzumab in the treatment of non-Hodgkin B cell lymphoma in our center. Methods ：We analysed the non-Hodgkin B cell lymphoma patients who received Obinutuzumab combined with chemotherapy or maintenance treatment during September 2021 and July 2023, median follow up 9 months（1-20）, to evaluate efficacy and safety. Results:In all 165 patients, male 88（53%), female 77（47%）, median 56 (26-83) years.

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Rodrigues, Pedro Mendes de Azambuja, Edgard do Carmo Neto, Luiz Rodrigo de Carneiro Santos, and Marcos Freitas Knibel. "Pneumonia associada à ventilação mecânica: epidemiologia e impacto na evolução clínica de pacientes em uma unidade de terapia intensiva." Jornal Brasileiro de Pneumologia 35, no. 11 (2009): 1084–91. http://dx.doi.org/10.1590/s1806-37132009001100005.

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OBJETIVO: Apesar de representar uma das principais causas de infecção nosocomial, o papel da pneumonia associada à ventilação mecânica (PAVM) no prognóstico ainda permanece indefinido. O objetivo deste estudo foi avaliar o impacto dessa doença na evolução clínica dos pacientes. MÉTODOS: Estabeleceu-se uma coorte prospectiva de 233 pacientes sob ventilação mecânica (grupo PAV, n = 64; grupo controle, n = 169). Os desfechos primários foram tempo de ventilação mecânica (TVM), tempo de permanência na UTI (TUTI), tempo de permanência hospitalar (TH) e mortalidade na UTI. Os desfechos secundários fo

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Permatasari, Gita Ayu, Minsih Zifa, and Siti Fatimah. "Peningkatan Keaktifan Belajar Ppkn Melalui Media Powerpoint Interaktif Pada Siswa Kelas IV A Di SDN 1 Panunggalan." Educatif Journal of Education Research 4, no. 1 (2021): 36–43. http://dx.doi.org/10.36654/educatif.v4i1.90.

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Penelitian tindakan kelas ini bertujuan untuk meningkatkan keaktifan belajar PPKn siswa kelas IV A melalui media power point interaktif di SDN 1 Panunggalan. Metode penelitian yang digunakan adalah Penelitian Tindakan Kelas. Hasil penelitian yang telah dilakukan, adanya peningkatan keaktifan belajar siswa kelas IV A pada indikator kesiapan mengikuti pelajaran pada kondisi pra siklus sebanyak 7 siswa (29%) , siklus I sebanyak 13 siswa (54%), siklus II sebanyak 20 siswa (83%). Indikator aktif memperhatikan penjelasan guru pada kondisi pra silus sebanyak 6 siswa (26%), siklus I sebanyak 7 siswa (

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39

Trivitayanurak, W., P. J. Adams, D. V. Spracklen, and K. S. Carslaw. "Tropospheric aerosol microphysics simulation with assimilated meteorology: model description and intermodel comparison." Atmospheric Chemistry and Physics 8, no. 12 (2008): 3149–68. http://dx.doi.org/10.5194/acp-8-3149-2008.

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Abstract. We implement the TwO-Moment Aerosol Sectional (TOMAS) microphysics module into GEOS-CHEM, a CTM driven by assimilated meteorology. TOMAS has 30 size sections covering 0.01–10 μm diameter with conservation equations for both aerosol mass and number. The implementation enables GEOS-CHEM to simulate aerosol microphysics, size distributions, mass and number concentrations. The model system is developed for sulfate and sea-salt aerosols, a year-long simulation has been performed, and results are compared to observations. Additionally model intercomparison was carried out involving global

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Rzayev, R. S. "ХАРАКТЕРИСТИКА КЛИНИЧЕСКИХ СИМПТОМОВ ЭРЕКТИЛЬНОЙ ДИСФУНКЦИИ У МУЖЧИН С СОМАТИЧЕСКОЙ ПАТОЛОГИЕЙ". Azerbaijan Medical Journal, № 2 (28 вересня 2024): 53–57. http://dx.doi.org/10.34921/amj.2024.16.90.001.

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Məqalədə somatik patologiyasi olan kişilərdə erektil disfunksiyanin klinik əlamətlərinin xüsusiyyətlərini öyrənmək məqsədilə aparılmış tədqiqat işi haqqında məlumat verilmişdir. Bu məqsədlə tədqiqata 2015-ci ildən 2020-ci illər ərzində erektil disfunksiya (ED) diaqnozu qoyulan, yaşı 25-dən 65-ə qədər olan 117 pasiyent cəlb edilmişdir. Pasiyentlər 2 qrupa bölünmüşdür: I qrup – venoz ED olan xəstələr – 75 kişi və II qrup – qarışıq venoz-arterial ED olan xəstələr – 42 kişi. Tədqiqat göstərmişdir ki, qruplar üzrə ED-nin xüsusiyyətləri arasında olan fərqlərlə hemodinamika pozulmalarının şiddəti ara

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41

Harzstark, A. L., T. M. Beer, V. K. Weinberg, et al. "Intermittent chemotherapy (ICh) for metastatic castration-resistant prostate cancer (mCRPC): Results of a prospective randomized phase II trial of the DoD Prostate Cancer Clinical Trials Consortium." Journal of Clinical Oncology 29, no. 7_suppl (2011): 133. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.133.

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133 Background: Docetaxel remains the standard of care for patients (pts) with mCRPC. However, the optimal duration of chemotherapy (Ch) is not known. Providing Ch holidays is often undertaken, but is not well characterized. A randomized phase II trial was undertaken to test two ICh regimens. Methods: Pts with Ch naive mCRPC and KPS > 60% were eligible. Pts were treated with “induction” docetaxel 75 mg/m2 q3 weeks, and prednisone 5 mg po bid. After 6 cycles, responding pts (PSAWG1 criteria) stopped Ch and were randomized to observation (Obs) or to GM-CSF, 250 mcg/m2 sq daily for 14 days out

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Faisal, Muhammad. "ANALISIS RISIKO PADA TAHAP PELAKSANAAN KONSTRUKSI JALAN TOL CINERE – JAGORAWI, DEPOK." Jurnal Proyek Teknik Sipil 4, no. 1 (2021): 33–42. http://dx.doi.org/10.14710/potensi.2021.10424.

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Cinere-Jagorawi Toll Road is a part of Jakarta Outer Ring Road (JORR) II which has the total length of 110 kilometer that circle around Seokarta-Hatta International Airport until Tanjung Priok. By the existance of JORR II, there would be an easy access from seaport to airport and vice versa. This also would be streamlining traffic flow from west to east considering the traffic at JORR I has overused which could cause congestion. In every construction of the Toll Road, there would be some risks that possibly arise. To minimize the risks that could occur, identification, anlysis, mitigation and

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Evens, Andrew M., Ranjana H. Advani, Irene B. Helenowski, et al. "Multicenter Phase II Study of Sequential Brentuximab Vedotin and Doxorubicin, Vinblastine, and Dacarbazine Chemotherapy for Older Patients With Untreated Classical Hodgkin Lymphoma." Journal of Clinical Oncology 36, no. 30 (2018): 3015–22. http://dx.doi.org/10.1200/jco.2018.79.0139.

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Purpose To improve the curability of older patients with newly diagnosed Hodgkin lymphoma. Patients and Methods We conducted a multicenter phase II study that administered brentuximab vedotin (Bv) sequentially before and after standard doxorubicin, vinblastine, and dacarbazine (AVD) for untreated patients with Hodgkin lymphoma age 60 years or older. After two lead-in doses of single-agent Bv (1.8 mg/kg once every 3 weeks), patients received six cycles of AVD chemotherapy followed by four consolidative doses of Bv in responding patients. Results Patient characteristics included median age of 69

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Zabel, Morgan, Tony W. Wilson, Harlan Sayles, Pamela E. May, Renae Furl, and Sara H. Bares. "The Impact of the COVID-19 Pandemic on Mental Health and Substance Use among People with and without HIV." Pathogens 12, no. 3 (2023): 461. http://dx.doi.org/10.3390/pathogens12030461.

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People with HIV (PWH) may be particularly vulnerable to the psychological impacts of COVID-19. To assess this, participants were recruited from two established cohorts of PWH and HIV− adults with the available pre-pandemic baseline data and completed the Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), Alcohol Use Identification Test (AUDIT), National Institute on Drug Abuse Quick Screen (NIDA-QS), and Pittsburgh Sleep Quality Index (PSQI) at two distinct intra-pandemic time periods. All outcomes were evaluated using generalized linear mixed models. In total, 87 participant

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Elmore, Michelle F., and Kim Mullenix. "137 Application of Performance Metrics to Evaluate Cow Performance: A Collaboration of the Alabama Beef Cattle Improvement Association and the Alabama Cooperative Extension System." Journal of Animal Science 100, Supplement_1 (2022): 5. http://dx.doi.org/10.1093/jas/skac028.008.

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Abstract Beef cattle producers engaged in the Alabama Beef Cattle Improvement Association (BCIA) Commercial Record Keeping Program are encouraged to expand records for evaluation of whole herd performance. Collection of cow weight at calf weaning can be used as a metric to estimate cow performance for overall productivity. From 2019 to 2021, five beef cattle operations annually collected individual cow weight at calf weaning (n = 284 observations). Cow age was classified as 2 to 4 years old, 5 to 8 years old and 9 years and older. Cow weight was classified into three categories as small (1199

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Garland, L. L., K. Chansky, A. Wozniak, et al. "SWOG S0509: A phase II study of novel oral antiangiogenic agent AZD2171 (NSC-732208) in malignant pleural mesothelioma." Journal of Clinical Oncology 27, no. 15_suppl (2009): 7511. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.7511.

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7511 Background: Preclinical studies suggest the autocrine growth loop involving VEGF and its receptors is a relevant therapeutic target for malignant pleural mesothelioma (MPM). We evaluated AZD2171, a potent tyrosine kinase inhibitor (TKI) of VEGFR1/2 in MPM. Methods: MPM patients (pts) after platinum-based chemotherapy, with PS 0–2, measurable disease and adequate organ function were treated with oral daily dosing of AZD2171 45 mg. Study endpoints were response rate, progression free survival (PFS), overall survival (OS), frequency/severity of toxicities, and correlation of clinical outcome

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Rzayev, R. S. "ОСОБЕННОСТИ КЛИНИЧЕСКИХ СИМПТОМОВ ЭРЕКТИЛЬНОЙ ДИСФУНКЦИИ У МУЖЧИН С СОМАТИЧЕСКОЙ ПАТОЛОГИЕЙ". Azerbaijan Medical Journal, № 1 (28 березня 2024): 91–95. http://dx.doi.org/10.34921/amj.2024.1.014.

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Məqalədə somatik patologiyası olan kişilərdə erektil disfunksiyanin klinik əlamətlərinin xüsusiyyətlərini öyrənmək məqsədilə aparılmış tədqiqat işi haqqında məlumat verilmişdir. Bu məqsədlə tədqiqata 2016-ci ildən 2020-ci ilə qədər erektil disfunksiya (ED) diaqnozu ilə müalicə almış, yaşı 25-dən 65-ə qədər olan 117 pasiyent cəlb edilmişdir. Pasiyentlər 2 qrupa bölünmüşdür: I qrup: venoz ED olan xəstələr - 75 kişi və II qrup: qarışıq venoz-arterial ED olan xəstələr - 42 kişi. Tədqiqat göstərmişdir ki, qruplar üzrə ED-nin xüsusiyyətləri arasında olan fərqlərdə hemodinamika pozulmalarının şid

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48

Irawan, Fajar Awang, Sutaryono Sutaryono, Dhias Fajar Widya Permana, Long-Ren Chuang, and Yuwono Yuwono. "Locomotor Skills: Traditional Games in the Fundamental of Physical Activities." Al-Athfaal: Jurnal Ilmiah Pendidikan Anak Usia Dini 4, no. 1 (2021): 1–13. http://dx.doi.org/10.24042/ajipaud.v4i1.8215.

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Motor coordination will be hampered if the stimulation of children's movement development tends to be neglected. This will have an impact on the child's movement skills. The purpose of this study was to determine traditional games in basic physical activities using locomotor skills. This study uses Classroom Action Research (PTK) which aims to see how much increase in the application of traditional games. The research was conducted at Madrasah Ibtidaiyah Lerep Ungaran Barat and this study used male students aged 7-9 years. There were 18 children who followed and participated in traditional gam

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Montanari, Francesca, Meina Lu, Sara Marcus, Ankeeta Saran, Aditya Malankar, and Amitabha Mazumder. "A Phase II Trial of Chloroquine in Combination with Bortezomib and Cyclophosphamide in Patients with Relapsed and Refractory Multiple Myeloma." Blood 124, no. 21 (2014): 5775. http://dx.doi.org/10.1182/blood.v124.21.5775.5775.

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Abstract Background: preclinical data suggest that autophagy can serve as an adaptive mechanism facilitating tumor cell survival and resistance to therapy-induced apoptosis. Subsequently, inhibitors of autophagy are thought to enhance the efficacy of therapeutic strategies designed to induce tumor cell apoptosis. Based upon our preclinical results, we hypothesized that the addition of chloroquine, an autophagy inhibitor, to the combination of a proteasome inhibitor, and cyclophosphamide might result in a synergistic effect. Patients and Methods: We designed a phase II trial of bortezomib, cycl

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Vilensky, Viktor A., Andrey A. Pozdeev, Timur F. Zubairov, Ekaterina A. Zakharyan, and Aleksander P. Pozdeev. "Treatment of pediatric patients with lower extremity deformities using software-assisted Ortho-SUV Frame: analysis of 213 cases." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 4, no. 4 (2016): 21–32. http://dx.doi.org/10.17816/ptors4421-32.

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Aim. To retrospectively assess treatment outcomes of long bone deformities of the lower extremities accompanied by shortening in pediatric patients using a software-assisted Ortho-SUV Frame.Materials and methods. The accuracy of deformity correction (AC), period of deformity correction (PDC), external fixation index (EFI), and number of complications in 213 patients were retrospectively analyzed.Results. According to different parameters, AC of femur deformity correction (group 1) varied from 90% to 96%. The average length increase was 47 ± 12 mm. The average distraction duration was 38 ± 14 d

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