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1

Fornari, Gianni, Elisa Artusio, Lorenza Mairone, et al. "Paclitaxel and Carboplatin in Neo-Adjuvant and Concomitant Chemoradiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma." Tumori Journal 88, no. 6 (2002): 489–94. http://dx.doi.org/10.1177/030089160208800611.

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Aim and background To evaluate feasibility of neoadjuvant chemotherapy (NA-CT) followed by CT + radiotherapy (RT) in locally advanced or unresectable head and neck squamous cell carcinoma (HNSCC). Methods 22 HNSCC patients were enrolled (18 males, 4 females; median age, 59.5 years; median ECOG PS, 1). Sites of disease: oral cavity, 18.2%; oropharynx, 40.9%; hypopharynx, 18.2%; larynx, 4.6%, multiple sites, 18.2%. T (tumor) category: T2, 13.6%; T3, 31.8%;T4, 54.5%. N (nodes) category: N0, 9.1%; N1, 18.1%; N2, 40.9%; N3, 31.8%. Stage: III, 4.6%; IVA, 63.6%; IVB, 31.8%. Induction carboplatin (AUC
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2

Pruitt, Margaret, Rajesh Naidu Janapala, and Faysal Haroun. "Patterns of lung cancer in people living with human immunodeficiency virus (HIV): A retrospective, single-center study in Washington, D.C." Journal of Clinical Oncology 39, no. 15_suppl (2021): e21154-e21154. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e21154.

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e21154 Background: Lung cancer is the leading cause of cancer death and the most common non-acquired immune deficiency syndrome defining malignancy in people living with HIV (PLWH). Disparities in outcomes have been observed despite lung cancer mortality reportedly decreasing in the general population over the last decade due to lower rates of smoking and the advent of novel therapies. To better understand the current trend in lung cancer in PLWH, we explored demographic characteristics, comorbidities, and lung cancer pathology and molecular data in this population. Methods: A retrospective se
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3

Miletic, Marija, Razia Aslam, Catey Bunce, et al. "Therapeutic approaches and outcomes in patients aged 50+ with germ cell tumours." Journal of Clinical Oncology 43, no. 5_suppl (2025): 636. https://doi.org/10.1200/jco.2025.43.5_suppl.636.

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636 Background: Testicular germ cell tumours (GCT) are the most common malignancy in young men, mainly in their 30s. While multimodal treatment leads to excellent survival in younger patients (pts), its incidence is rising in men over 50, who often have comorbidities and higher risks of chemotherapy (ChT) toxicity. Limited data on outcomes in this group highlights the need for more research. Methods: We conducted a retrospective single centre study, analysing pts diagnosed with GCT aged 50 years or older between 2014 -2023. Results: 142 pts were analysed, median age of 57 years (range 50–83).
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Lai-Kwon, Julia Elizabeth, Michael Jefford, Ashkan Mehrnejad, et al. "Financial toxicity and employment outcomes in people with melanoma receiving adjuvant therapies." Journal of Clinical Oncology 43, no. 16_suppl (2025): 9577. https://doi.org/10.1200/jco.2025.43.16_suppl.9577.

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9577 Background: One year ofadjuvant anti-programmed cell death protein-1 (anti-PD1) or dabrafenib-trametinib are standards of care for patients (pts) with resected stage III-IV melanoma. The impact of adjuvant therapy on a pt’s employment, income, and level of financial toxicity are unknown. We examined these outcomes up to 2 years post initiation of adjuvant therapy. Methods: A prospective, longitudinal study of pts with resected stage IIB-IV melanoma receiving adjuvant anti-PD1 or dabrafenib-trametinib at an Australian comprehensive cancer center. Two customized employment surveys assessed
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Abouyabis, Abeer N., MaryJo Lechowicz, Karen Mann, et al. "Benefits of CHOP-14 Followed by Transplantation in Patients with Peripheral T-Cell Lymphoma." Blood 108, no. 11 (2006): 4689. http://dx.doi.org/10.1182/blood.v108.11.4689.4689.

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Abstract Background: Compared to B-cell lymphomas, peripheral T-cell non-Hodgkin lymphomas (PTCL) represent a subtype that more frequently involve extranodal sites and worse relapse free survival (RFS) and overall survival (OS) with and without risk stratification by the international prognostic index (IPI). Moreover, while traditional anthracycline containing regimens can induce complete remission (CR), they have not significantly improved long-term outcomes for patients (pts) with PTCL and resulted in 5-year OS and failure-free survival of 26% and 20%, respectively. We examined the pathologi
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6

Gisslinger, Heinz, Veronika Buxhofer-Ausch, Josef Thaler, et al. "Efficacy and Safety Of AOP2014/P1101, a Novel, Investigational Mono-Pegylated Proline-Interferon Alpha-2b, In Patients With Polycythemia Vera (PV): Update On 51 Patients From The Ongoing Phase I/II Peginvera Study." Blood 122, no. 21 (2013): 4046. http://dx.doi.org/10.1182/blood.v122.21.4046.4046.

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Abstract Background AOP2014/P1101 is a novel, investigational mono-pegylated proline-interferon alpha-2b. In contrast to other pegylated IFNs, AOP2014/P1101 consists of one predominant isoform. AOP2014/P1101 has Orphan Drug Designation in EU and USA for treatment of patients with PV. Study design Long term efficacy and safety data are being collected in the follow-up extension stage of the study (collecting the data of both Phase I and Phase II portions of the study), after the maximum tolerated dose (MTD) of AOP2014, administered subcutaneously every 14 days, has been defined earlier. Patient
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7

Khurana, Arushi, Raphael Mwangi, James R. Cerhan, et al. "Comparing Clinical Characteristics and Outcomes of MYC and BCL6 Double Hit Lymphoma (DHL- BCL6) with Other Aggressive B-Cell Lymphomas: Understanding the Impact of New Who and International Consensus Classifications." Blood 142, Supplement 1 (2023): 67. http://dx.doi.org/10.1182/blood-2023-190316.

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Background: High Grade B cell Lymphoma (HGBL) with MYC and BCL2 and/or BCL6 rearrangements(R) was introduced as an entity in 2016 by the WHO revised 4 th edition. In 2022, both the WHO 5 th edition (beta version) and the International Consensus Classification (ICC) separated DHL- BCL2 (+/- BCL6-R)from DHL- BCL6 given differences in biology . However, while the ICC has maintainedDHL- BCL6 as a provisional entity, the WHO has removed the category, thus removing the requirement to FISH for BCL6-R in this setting. Clinical data on DHL- BCL6 is much more limited, as these cases represent only 10-20
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8

Astibia Mahillo, Beatriz, María-Jesús Blanchard, Miguel Piris Villaespesa, et al. "Clinical, Biological and Prognostic Characterization of Multiple Myeloma According to the Presence of Circulating Plasma Cells." Blood 144, Supplement 1 (2024): 3349. https://doi.org/10.1182/blood-2024-210589.

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Introduction: According to the updated IMWG consensus definition patients with symptomatic multiple myeloma (MM) presenting with ≥5% circulating plasma cells (cPC) by cytomorphology should be considered as having plasma cell leukemia (PCL). It is a matter of debate whether patients with cPC <5% are associated with an adverse prognosis. The objective of this study is to characterize and evaluate the prognosis of MM according to the level of cPC. Methods: Single-center retrospective study of patients diagnosed with symptomatic MM between 2019-2022 (N=77). A blinded review of blood smears
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9

Hoelzer, Dieter, Nicola Goekbuget, Joachim Beck, et al. "Subtype Adjusted Therapy Improves Outcome of Elderly Patients with Acute Lymphoblastic Leukemia (ALL)." Blood 104, no. 11 (2004): 2732. http://dx.doi.org/10.1182/blood.v104.11.2732.2732.

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Abstract Despite the major peak of ALL in childhood the incidence also increases in the elderly beyond 50 yrs. Outcome of these elderly ALL pts is very poor. In a survey including 12 studies with 370 pts (50–88 yrs) the mean CR rate was 50% and the rate of continuous CR (CCR) 13%. Also in a first prospective pilot study of the German Multicenter Study Group for Adult ALL (GMALL) for elderly ALL pts > 65 yrs with a moderate intensive chemotherapy regimen (Blood, 96(11): 3104a, 2000) the results in 94 pts were poor with a CR rate of 48% and a survival (OS) <10%. Therefore in 2003 t
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10

Mark, Tomer M., Abbe Schickner, John N. Allan, et al. "Car-Bird [Carfilzomib, Clarithromycin(Biaxin®), Lenalidomide/(Revlimid®), Dexamethasone) for Newly-Diagnosed Multiple Myeloma." Blood 124, no. 21 (2014): 4761. http://dx.doi.org/10.1182/blood.v124.21.4761.4761.

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Abstract Background: Carfilzomib (Cfz), lenalidomide, and dexamethasone synergize to provide an impressive overall response rate (ORR) in upfront treatment of multiple myeloma (MM) (Jakubowiak et al 2012). The ORR to Cfz+dexamethasone (Cfz-Dex) as first-line therapy is unknown. We hypothesized that sequential treatment with Cfz-dex and BiRD would improve provide similar ORR and improve tolerability. A protocol of Cfz-Dex, consolidation with BiRd (Clarithromycin(Biaxin¨), Lenalidomide/(Revlimid¨), dexamethasone), and lenalidomide maintenance (Len) was conducted to evaluate ORR and safety as ind
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11

RYKHAL, V., A. OKOPNYY, N. HUTSUL, and O. DONETS. "CHANGES IN TECHNICAL TRAINING OF KICKBOXERS OF MEDIUM WEIGHT CATEGORIES AT THE STAGE OF PRELIMINARY BASIC TRAINING." Pedagogical Sciences, no. 79 (September 19, 2022): 37–43. http://dx.doi.org/10.33989/2524-2474.2022.79.264521.

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The article analyzes the comparative assessment of improving the technical training of middleweight kickboxers at the stage of preliminary basic training. The study involved 60 kickboxers who were at the stage of preliminary basic training, the age of athletes from 10 to 13 years. The experimental group included 30 medium weight category kickboxers (subgroup I (40 kg), subgroup II (45 kg) and subgroup III (50 kg)) in the KG 30 medium weight category kickboxers (subgroup I (40 kg), subgroup II (45 kg), subgroup II (45 kg) and III subgroup (50 kg)). The experimental group included kickboxers of
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12

Intermesoli, Tamara, Alessandro Rambaldi, Chiara Cattaneo, et al. "High Cure Rates in Burkitt Leukemia and Lymphoma: NILG Study of the German Short Intensive Rituximab-Chemotherapy Program." Blood 120, no. 21 (2012): 1494. http://dx.doi.org/10.1182/blood.v120.21.1494.1494.

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Abstract Abstract 1494 Introduction: Burkitt lymphoma (BL) and B-cell acute lymphoblastic leukemia (B-ALL) are very aggressive malignancies with poor prognosis unless treated with highly specific intensive programs. The German Multicenter Study Group for Adult ALL piloted a short intensive rituximab (R)-chemotherapy program that improved outcome compared to the prior regimen (Hoelzer et al, Blood 110:abstr 518, 2007). The Northern Italy Leukemia Group adopted the same protocol to treat 105 consecutive, unselected adult patients with BL and B-ALL. Aim: To assess long-term outcome and toxicity a
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13

Pereira, Chirag. "Malignancy Rates in Thyroid Nodules Classified as Bethesda III and IV; Correlating Fine Needle Aspiration Cytology with Histopathology." Prague Medical Report 123, no. 4 (2022): 243–49. http://dx.doi.org/10.14712/23362936.2022.22.

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Fine needle aspiration cytology (FNAC) is an integral part in the diagnostic work up of thyroid nodules. FNAC reports are based on Bethesda system for thyroid cytopathology which is one of the most commonly used systems worldwide. The main objective of the present study was to evaluate the malignancy rates in Bethesda category III and IV thyroid nodules over a six-year period. 642 thyroid FNAC were performed over a six-year period. The medical records of all these patients were reviewed using electronic patient records. Cases reported to have Bethesda category III and IV were included in the s
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14

Brown, Jennifer R., Bruce D. Cheson, Richard R. Furman, et al. "Patterns of Lymphocytosis in Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Treated with Idelalisib." Blood 126, no. 23 (2015): 2952. http://dx.doi.org/10.1182/blood.v126.23.2952.2952.

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Abstract Background Lymphocytosis is a known pharmacologic effect of B-cell receptor (BCR) targeted therapies used in the treatment of CLL and SLL. It has been reported that prolonged lymphocytosis after treatment with a BTK inhibitor was more common in patients (pts) with mutated immunoglobulin heavy chain variable region (IGHV) genes. Idelalisib (IDL) is a selective oral PI3Kd inhibitor. In the phase I idelalisib monotherapy (IDL-mono) trial (NCT00710528), the majority of pts with CLL/SLL experienced a transient increase in absolute lymphocyte count (ALC) accompanied by a reduction of lympha
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15

Pandey, Neha, Goutami DasNayak, Kanakalata Dash, Urmila Senapati, and Khageswar Rout. "Application of the Milan System of reporting salivary gland cytopathology and assessing its use as a risk stratification tool." Journal of Cancer Research and Therapeutics 20, no. 5 (2024): 1517–23. http://dx.doi.org/10.4103/jcrt.jcrt_225_23.

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ABSTRACT Introduction: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was proposed by American Society of Cytopathology and International Academy of Cytology to standardize reporting system ensuring uniformity and better communication between clinicians and cytopathologists. Aims and Objectives: 1. To categorize salivary lesions as per MSRSGC. 2. To establish diagnostic accuracy of MSRSGC and calculate risk of malignancy for each diagnostic category. Materials and Methods: An ambispective study was conducted over 5 years including 45 FNAC cases of salivary lesions. The ca
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16

Nurhayati, Nurhayati. "Pengembangan Media Puzzle Terhadap Hasil Belajar Pada Tema 8 Subtema 1 Pembelajaran 2 Siswa Kelas III di Sekolah Dasar." Jurnal Pendidikan Indonesia 2, no. 2 (2024): 100–110. https://doi.org/10.62007/joupi.v2i2.301.

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This study aims to determine the development of puzzle media on the learning outcomes of grade III students at SDN 15 Sungai Pinyuh. The research method used is the development research method (Research & Development) while the research model used, namely 4-D with the stages of design, definition, development and dissemination, The subjects in this research are grade III students of SDN 15 Sungai Pinyuh, totaling 45 students consisting of 24 male students and 21 female students. The validation technique used is in the form of collecting data on learning outcome tests. In data collection, a
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Hidayati, Kurnia, and Nur Qhoufi Khuzaini. "Komparasi Minat Belajar Siswa Kelas III MI Ma’arif Mayak Ponorogo dengan Menggunakan Alat Peraga Papan Pecahan." IMEJ : Indonesian Mathematics Education Journal 1, no. 1 (2024): 11–22. http://dx.doi.org/10.21154/imej.v1i01.1.

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Interest is a person's favourite, favourite thing about something. The tedious learning process of mathematics tends to make students less interested in learning material, so one of the efforts made in the learning process is by using fraction board props on simple fraction material. The research method used is a comparison with the independent sample t-test. The research was conducted at MI Ma'arif Mayak Ponorogo with a sample size of 50 students consisting of 2 classes, namely class 3a as the experimental class and class 3b as the control class. The data collection technique used a questionn
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18

Simmons, Gary, Roy Sabo, Maja Radic, et al. "Safety and Tolerability of Intra-Venous Ascorbic Acid in Allogeneic Hematopoietic Cell Transplant Recipients: A Matched Historical Control Study." Blood 136, Supplement 1 (2020): 29–30. http://dx.doi.org/10.1182/blood-2020-138543.

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Intravenous (IV) ascorbic acid (AA) improves organ function and reduces inflammation in sepsis, an inflammatory state similar to the post-hematopoietic cell transplant (HCT) milieu. This salutary effect is mediated by antioxidant activity as well transcriptional modulation by AA. HCT recipients are deficient in AA, therefore we evaluated the safety and efficacy of patients receiving parenteral AA after myeloablative conditioning for allogeneic HCT compared to similarly treated historical controls who did not receive AA. Methods: Patients with hematologic malignancies, AML (48% of patients), AL
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19

Lupattelli, Marco, Ernesto Maranzano, Rita Bellavita, et al. "Raltitrexed and Radiotherapy as Adjuvant Treatment for Stage II-III Rectal Cancer: A Feasibility Study." Tumori Journal 91, no. 6 (2005): 498–504. http://dx.doi.org/10.1177/030089160509100610.

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Aims and Background Adjuvant 5-FU chemotherapy plus radiotherapy represents the standard treatment for radically resected rectal cancer at high risk of relapse according to the NIH Consensus Conference. The therapeutic gain was obtained with a high rate of severe treatment-related toxicity and a sub-optimal patient compliance with this regimen. Raltitrexed is a specific thymidylate synthase inhibitor with a convenient administration schedule, acceptable toxicity and radiosensitizing properties, as the published phase I trials in combination with radiotherapy have shown. The aim of this prospec
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Palomo, Laura, Blanca Xicoy, Olga Garcia, et al. "Utility of SNP Arrays in Chronic Myelomonocytic Leukemia with Low Risk Cytogenetic Features or No Metaphases." Blood 124, no. 21 (2014): 4659. http://dx.doi.org/10.1182/blood.v124.21.4659.4659.

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Abstract Background: Clinical, morphological and genetic characteristics of chronic myelomonocytic leukemia (CMML) are heterogeneous and vary from a myelodysplastic predominant profile to a myeloproliferative one. CMML has a highly variable course, with a median overall survival (OS) of 20 months and 15-30% of progression to acute myeloid leukemia (AML). Cytogenetic abnormalities are present in only 20-40% of cases. CMML-specific cytogenetic risk classification stratifies karyotypes into three groups: low risk (normal karyotype and isolated loss of Y chromosome, -Y), poor risk (trisomy 8, mono
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21

Moltu, Amy, Lei-Lei Tun, Dhanjeev Marrie, and Tandrila Sinha. "Improving Accuracy of ACE-III Marking in the Wyre Forest Older Adult Community Mental Health Team." BJPsych Open 11, S1 (2025): S151—S152. https://doi.org/10.1192/bjo.2025.10407.

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Aims: Accurate implementation and marking of the ACE-III (Addenbrooke’s Cognitive Examination) within memory assessments is vital in informing clinical diagnoses. The 100-mark cognitive test is subject to various nuances in its marking criteria that can easily be overlooked or misinterpreted.Given noticeable discrepancy in staff completion, we aimed to review the accuracy of scoring of the ACE-IIIs completed by the team. We sought to identify the domains with the greatest variability in scoring, hypothesising that this would be the visuospatial domain, and feed this back as a teaching session
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22

Hoque, Rezwanul, Sabrina Sharmeen Hussain, Md Abdul Quaium Chowdhury, et al. "Carotid Body Tumor - A Case Reports." University Heart Journal 8, no. 1 (2012): 58–61. http://dx.doi.org/10.3329/uhj.v8i1.11670.

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Carotid body tumor, an extra-adrenal paraganglioma, represents an uncommon entity arising in chemoreceptor tissue located at the carotid bifurcation. They commonly present as asymptomatic neck masses and careful preoperative evaluation is required to find out the functional and vascular status of these tumours. An unusual case of a large (70 × 50 × 45 mm) carotid body tumor of Shamblin type III in a 50 year old male is being presented here. The evaluation, management and the final outcome of this case of carotid body tumour is being reported here. DOI: http://dx.doi.org/10.3329/uhj.v8i1.11670
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23

Orel, A. M. "Types of the statics of the spine in patients of young, elderly and senile age." Russian Osteopathic Journal, no. 1-2 (June 6, 2020): 38–48. http://dx.doi.org/10.32885/2220-0975-2020-1-2-38-48.

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Introduction. A complete and systematic x-ray examination of all parts of the spine at the same time in elderly and senile people has not yet been carried out. On the other hand, radiography can identify spinal statics disorders that are typical for this category of people.The goal of research — describe the types of spinal statics disorders in young, elderly and senile people.Materials and methods. Digital radiography of all parts of the spine was performed in 103 patients with dorsopathies. The first group included 50 patients aged 60–74 years; men 16, women 34. The second study group includ
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Casulo, Carla, Michelle Byrtek, Keith L. Dawson, et al. "Early Relapse Of Follicular Lymphoma After R-CHOP Uniquely Defines Patients At High Risk For Death: An Analysis From The National Lymphocare Study." Blood 122, no. 21 (2013): 510. http://dx.doi.org/10.1182/blood.v122.21.510.510.

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Abstract Introduction Despite gains in survival with aggressive upfront treatments, such as R-CHOP (rituximab, doxorubicin, vincristine, prednisone) for follicular lymphoma (FL), and the implementation of rituximab maintenance, approximately 20% of patients will still experience progression of disease (POD) within 24 months of chemoimmunotherapy, as demonstrated by the PRIMA study and others (Salles et al, Lancet 2010; Press et al, JCO 2013). This suggests a high-risk group of patients warranting further study. We analyzed the National LymphoCare Study to identify patients with FL who are at h
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Ulyanov, M. V., and M. I. Fomichev. "Research of Features of the Combined Algorithm for Solving the Asymmetric Traveling Salesman Problem." INFORMACIONNYE TEHNOLOGII 27, no. 1 (2021): 3–8. http://dx.doi.org/10.17587/it.27.3-8.

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The exact algorithm that implements the Branch and Boimd method with precomputed tour which is calculated by Lin-Kernighan-Helsgaun metaheuristic algorithm for solving the Traveling Salesman Problem is concerned here. Reducing the number of decision tree nodes, which are created by the Branches and Bound method, due to a "good" precomputed tour leads to the classical balancing dilemma of time costs. A tour that is close to optimal one takes time, even when the Lin-Kernighan-Helsgaun algorithm is used, however it reduces the working time of the Branch and Bound method. The problem of determinin
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Paskalia Tarigan. "Peningkatan Hasil Belajar Pendidikan Agama Katolik melalui Model PBL Berbantuan Media Audio Visual di Kelas III SDN 101802 Namorambe." PROSIDING SEMINAR NASIONAL PENDIDIKAN DAN AGAMA 5, no. 2 (2024): 2652–66. http://dx.doi.org/10.55606/semnaspa.v5i2.2267.

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This study aims to determine the improvement of learning outcomes by using the based learning model in class IV of SDN 101802 Namorambe. This study used the Classroom Action Research (CAR) method, the population of this study were Catholic students in class III of SDN 101802 Namorambe totaling 8 students consisting of 4 males and 4 females. Sampling using purposive sampling and the sample used was class III totaling 8 students. The results of this study indicate that student learning outcomes using the based learning model are included in the very good category seen that the average post-test
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Astuti Zulfiana, Putri, Dewinta Mutiara, and Episiasi Episiasi. "Analisis Minat Belajar Siswa Kelas III Pada Pembelajaran IPA di SDN 45 Lubuklinggau." ULIL ALBAB : Jurnal Ilmiah Multidisiplin 4, no. 1 (2024): 416–24. https://doi.org/10.56799/jim.v4i1.6904.

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Penelitian ini bertujuan untuk mengetahui Analisis Minat Belajar Siswa kelas III Terhadap Hasil Belajar Siswa Pada Pembelajaran Ilmu Pengetahuan Alam. Adapun hal yang ingin di bahas dalam penelitian ini ialah: Bagaimana minat belajar siswa berpengaruh pada hasil belajar siswa dalam mata pelajaran IPA di SDN 45 Lubuklinggau. Maka penelitian ini menggunakan pendekatan kuantitatif dengan metode survey. Pengambilan sampel penelitian berjumlah 20 responden. Hasil penelitian ini adalah minat belajar siswa berpengaruh pada hal positif terhadap hasil belajar siswa dan menyebabkan hasil belajar yang ba
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Sroka, Radosław, Jerzy Eider, and Aleksander Wiażewicz. "The level of sports performance of people with intellectual disabilities in athletics competitions of Special Olympics." Journal of Kinesiology and Exercise Sciences 28, no. 81 (2018): 69–75. http://dx.doi.org/10.5604/01.3001.0012.7963.

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Background: The Special Olympics are dedicated to people with intellectual disability and multiple disabilities. The aim of the study was to define the level of athletics competition results for participants with intellectual disabilities. More over researchers tried to determine the impact of gender and age on the results obtained by people with mental disabilities. Material and methods: There were 1108 results (431 female, 677 male) achieved at Special Olympics events in 2016-2017. Competitors were divided into 4 age groups and competed in 8 track and field events. Results: There were no sta
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Hardiyani, Susilo, Fenny Roshayanti, Harto Nuroso, and M. Syaipul Hayat. "Analysis of Science Process Skills of Junior High School Students on The Concept of Elements, Compounds, and Mixtures Based on Education for Sustainable Development." Jurnal Penelitian Pendidikan IPA 11, no. 3 (2025): 660–64. https://doi.org/10.29303/jppipa.v11i3.10352.

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This research aims to analyze students' science process skills in solving science questions at State Middle Schools in Blora. This research uses a qualitative descriptive method. The instrument used in this research was a SPS test question in the form of an essay. The research data was carried out quantitatively and qualitatively. The results of the study show that the SPS of students at State Middle Schools in Blora on the concepts of elements, compounds, and mixtures is in the low category with an average of 50%. Based on the nine indicators analyzed, observing indicators have an average per
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Stoian, Dana, Florin Borcan, Izabella Petre, et al. "Strain Elastography as a Valuable Diagnosis Tool in Intermediate Cytology (Bethesda III) Thyroid Nodules." Diagnostics 9, no. 3 (2019): 119. http://dx.doi.org/10.3390/diagnostics9030119.

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Fine needle aspiration (FNA) is considered the gold standard in the diagnostic of thyroid nodules. Using the recommended BETHESDA reporting system, up to 20% of results are classified as intermediate cytology. As there is no consensus whether ultrasound evaluation, lobectomy or surgery is the best treatment option, intermediate cytology results are considered a grey zone of the FNA. The main aim of our study was to evaluate the performance of combined advanced ultrasound techniques in the process of diagnosis and evaluation of the intermediate cytology cases after FNA. We evaluated 54 consecut
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Adpriyadi, Adpriyadi. "Peningkatan kemampuan motorik kasar melalui permainan tradisional Engklek pada anak kelompok B." JPPM (Jurnal Pendidikan dan Pemberdayaan Masyarakat) 4, no. 2 (2017): 187–98. http://dx.doi.org/10.21831/jppm.v4i2.10016.

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Penelitian ini bertujuan untuk memperbaiki proses dan hasil pembelajaran sebagai upaya meningkatkan kemampuan motorik kasar anak kelompok B di TK Tunas Gading Yogyakarta. Jenis penelitian ini adalah penelitian tindakan kelas yang dilakukan dalam III siklus, subjek dalam penelitian ini adalah anak didik kelompok B TK Tunas Gading Yogyakarta tahun ajaran 2015/2016 yang berjumlah 16 anak yang terdiri dari 7 laki-laki dan 9 perempuan. Pengumpulan data dilakukan melalui unjuk kerja, Observasi dan dokumentasi. Teknik analisis data di lakukan dengan menggunakan statistik deskriptif sederhana, data di
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Dantey, Kossivi, Farhad Hasan, Ali Tipu, and Tanvi Verma. "ODP481 Frequency and outcomes of reporting Bethesda class III thyroid cytopathology- An integrated health network's experience." Journal of the Endocrine Society 6, Supplement_1 (2022): A766. http://dx.doi.org/10.1210/jendso/bvac150.1581.

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Abstract Introduction Indeterminate thyroid nodule cytologic diagnosis causes anxiety and confusion to the patient and typically results in additional intervention including thyroid surgery. This increases risk of harm and cost of healthcare. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) recommends that cytologists attempt to limit reporting 'indeterminate' [Bethesda III (B-III)] category when interpreting thyroid fine needle aspiration (FNA) specimens, and that all effort be made to limit this diagnosis to less or equal to 7% of all thyroid FNA cases. B-III encompasses foll
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Friska Junita and Hanita Indra Yuliana. "THE CORRELATION HUSBAND SUPPORT WITH READINESS TO FACE LABOR IN PREGNANT MOTHERS TRIMESTER III AT PARAMITRA MEDIKA 1 CLINIC BEKASI TAHUN 2021." Jurnal Medicare 1, no. 4 (2022): 171–82. http://dx.doi.org/10.62354/jurnalmedicare.v1i4.35.

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Pregnancy is an important event that demands the role of all family member, support during pregnancy is needed for pregnant women, especially from the closest people. Support and role from husband during pregnancy and childbirth has been shown to increase the readiness of pregnant women to face pregnancy and childbirth. Research Purpose : To determine the relationship between husband and readiness to face childbirth in third trimester pregnant women at Paramitra Medika 1 Clinic. Research Methods : This research was conducted at Paramitra Medika 1 Clinic on June 28 to July 30, 2021. This resear
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Natalina, Riny, and Legawati Legawati. "PEMBERIAN DAN DEMONSTRASI PENGOLAHAN JUS BAYAM MERAH UNTUK IBU HAMIL TRIMESTER I DAN II DENGAN ANEMIA DI PUSKESMAS BUKIT RAWI." EJOIN : Jurnal Pengabdian Masyarakat 2, no. 1 (2024): 74–78. http://dx.doi.org/10.55681/ejoin.v2i1.2168.

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Anemia is caused due to iron deficiency caused by physiological changes due to pregnancy that are aggravated by a state of lack of nutrients, vitamin B12, folic acid and vitamin C. The goal is to increase the ability of pregnant women in making red spinach juice and increase HB levels of third trimester pregnant women with anemia with consumption of red spinach juice. Method of activity: Pregnant women involved a total of 20 pregnant women and previously checked the Hb levels of pregnant women before being given red spinach juice, followed by a demo of making red spinach juice. After 14 days,
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Citrome, Leslie, Robert Goldman, Joyce Tsai, Ling Deng, Todd Grinnell, and Andrei Pikalov. "168 Effect of Dasotraline on Body Weight in Patients with Binge-Eating Disorder." CNS Spectrums 25, no. 2 (2020): 307. http://dx.doi.org/10.1017/s109285292000084x.

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Abstract:Background:Binge-eating disorder (BED) is associated with obesity (BMI ≥30) in approximately 40-45% of patients. Dasotraline is a long-acting dopamine/norepinephrine reuptake inhibitor with a PK profile characterized by slow absorption and an elimination half-life of 47-77 hours, permitting once-daily dosing. In a recent placebo-controlled, flexible-dose study, dasotraline demonstrated significant efficacy in patients with BED. We now report an analysis from this study of the effect of dasotraline on body weight.Method:Patients with moderate-to-severe BED, based on DSM-5 criteria, wer
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Shah, Mithun V., Monika Kutyna, Syed Shah, et al. "Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53-Mutations Using an Independent International Cohort." Blood 142, Supplement 1 (2023): 3243. http://dx.doi.org/10.1182/blood-2023-187860.

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BACKGROUND: Recently proposed World Health Organization (WHO, 5 th edition) and International Consensus Classification (ICC) recognized myeloid neoplasms (MN) harboring TP53-mutated ( TP53mut) as a separate entity. However, there are critical differences between the two classifications regarding allelic-status, variance allele frequency (VAF) cut-off and blast categories, that may lead to under- or overestimation of the risk. METHODS: We analyzed MN harboring TP53mut (VAF ≥2%, n=536) managed at Mayo Clinic (USA) and South Australia Health Network (Australia). ICC (Arber et al, Blood 2022) and
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Bohuslavska, Viktoriia, Ivan Hubar, Olena Demchenko, Inna Asauliuk, Nataliia Оliinyk, and Vadym Adamchuk. "Efficiency of using interactive means of theoretical training of swimmers 8-10 years old." Health, sport, rehabilitation 9, no. 4 (2023): 33–45. http://dx.doi.org/10.58962/hsr.2023.9.4.33-45.

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Purpose: substantiating and developing the structure and content of theoretical training of swimmers at the stage of initial training and determining the effectiveness of traditional and interactive means of theoretical training on the level of theoretical training of athletes.
 Material and methods. A sociological survey by means of a questionnaire was conducted among qualified swimmers and trainers-teachers in order to establish the actual problems of the theoretical training of swimmers.
 The total number of interviewed qualified swimmers was 32 people, the average age of the inte
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Kuberan, Abinaya, Sankeerthana MP, Jayakar Thomas, Shea Sharma, and Gopalakrishnan K. "Evaluation of lipid profile in young adults (18-50 years) with psoriasis vulgaris in Chennai." IP Indian Journal of Clinical and Experimental Dermatology 11, no. 1 (2025): 48–54. https://doi.org/10.18231/j.ijced.2025.007.

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Psoriasis is a chronic inflammatory and proliferative skin condition influenced by both genetic and environmental factors. Its typical manifestations include red, scaly, well-defined plaques that often appear on the extensor surfaces of the body and the scalp. The disease can vary significantly in terms of duration, frequency of flare-ups, and affected areas, and it often presents with various morphological variations.My study aims to primarily ascertain the frequency of lipid disturbances in patients with psoriasis vulgaris and their extent of derangement correlated with severity of psoriasis
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Muhali, Muhali, Roniati Sukaisih, and Muhammad Asy'ari. "Implementasi model reflective-metacognitive learning untuk meningkatkan kemampuan berpikir kritis, keterampilan metakognisi dan kesadaran metakognisi." Empiricism Journal 1, no. 2 (2020): 75–95. http://dx.doi.org/10.36312/ej.v1i2.337.

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Tujuan penelitian ini adalah untuk meningkatkan kemampuan berpikir kritis, keterampilan metakognisi, dan kesadaran metakognisi melalui implementasi model reflective metacognitive learning (RML) dalam pembelajaran fisika di MAN 3 Lombok Tengah. Penelitian ini merupakan penelitian tindakan kelas (PTK) yang dilaksanakan dalam 3 (tiga) siklus pembelajaran dan setiap siklus terdiri dari 3 (tiga) kali pertemuan. Instrumen penelitian ini terdiri dari lembar observasi keterlaksanaan pembelajaran, tes kemampuan berpikir kritis, lembar penilaian keterampilan metakognisi, dan angket kesadaran metakognisi
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Tomar, Amit, and D. K. Upadhyay. "Genetic Divergence Analysis in Mungbean (Vigna radiata L. Wilczek)." International Journal of Agricultural Invention 4, no. 01 (2019): 106–9. http://dx.doi.org/10.46492/ijai/2019.4.1.18.

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An experiment involving 45 genotypes/strains of mungbean was conducted during kharif 2018 at University Farm (Crop Cafeteria) of Rani Lakshmi Bai Central Agricultural University (RLBCAU), Jhansi in a Randomized Block Design with three replications. Data were recorded and analyzed for 10 characters viz.; days to 50% flowering, days to maturity, plant height (cm), number of primary branches per plant, number of clusters per plant, number of pods per plant, pod length (cm), number of seeds per pod, 100-seed weight (g) and grain yield per plant (g). All the forty five genotypes were grouped into s
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Destivani, Vika, Usep Kuswari, and Yatun Romdonah Awaliah. "KUALITAS SOAL PENILAIAN TENGAH SEMESTER MATA PELAJARAN BAHASA SUNDA DI SMPN 2 LEUWISADENG BOGOR." LOKABASA 11, no. 1 (2020): 73–81. http://dx.doi.org/10.17509/jlb.v11i1.25200.

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This research based on the quality of mid-semester test questions in Sundanese language subject which is proposed by the teacher is still not meeting the criteria of validity , reliability, and questions properness,. This research aims to describe the validity level, content validity, and empirical validity (difficulty level and differentiator power), reliability, and questions appropriateness level of Sundanese language subject in SMPN 2 Leuwisadeng Bogor. This research uses descriptive method, specifically, descriptive and inferential statistics. This methods used descriptive method of quant
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Tamarolo, Teti, Theo Welly Evert Mautang, and Richard Andreas Palilingan. "The Relationship Between Working Time And Musculoskeletal Complaints In Tailors In Lolak Market." Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) 9, no. 1 (2025): 48–57. https://doi.org/10.35910/jbkm.v9i1.1071.

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Background: This study was motivated by the high risk of musculoskeletal complaints in tailors due to non-ergonomic working postures and long working hours. The purpose of the study was to determine the relationship between working hours and musculoskeletal complaints in tailors at Pasar Lolak. Methods: Data were collected using a questionnaire on respondent characteristics and the Nordic Body Map (NBM) to measure musculoskeletal complaints. Data analysis used the Chi-Square test. Results: The majority of tailors at Pasar Lolak were aged 36-45 years, with more than 10 years of work experience
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DeKarske, Daryl, Gustavo Alva, Jason L. Aldred, et al. "An Open-Label, 8-Week Study of Safety and Efficacy of Pimavanserin Treatment in Adults with Parkinson’s Disease and Depression." Journal of Parkinson's Disease 10, no. 4 (2020): 1751–61. http://dx.doi.org/10.3233/jpd-202058.

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Background: Many patients with Parkinson’s disease (PD) experience depression. Objective: Evaluate pimavanserin treatment for depression in patients with PD. Methods: Pimavanserin was administered as monotherapy or adjunctive therapy to a selective serotonin reuptake inhibitor or serotonin/noradrenaline reuptake inhibitor in this 8-week, single-arm, open-label phase 2 study (NCT03482882). The primary endpoint was change from baseline to week 8 in Hamilton Depression Scale–17-item version (HAMD-17) score. Safety, including collection of adverse events and the Mini-Mental State Examination (MMSE
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Baraibar, Iosune, Francesc Salva, Raquel Comas, et al. "Young-onset colorectal cancer: A call for action." Journal of Clinical Oncology 39, no. 15_suppl (2021): 10563. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.10563.

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10563 Background: Young-onset colorectal cancer (YOCR) is defined as diagnosis below the age of 50. Over the past decades, the incidence of YOCRC has increased at an alarming rate, but causes and pathogenesis still remain unknown. Early detection of colorectal cancer (CRC) has demonstrated to improve survival. Despite these facts, adults < 50 years old are not yet included in screening programs and YOCRC is not well characterized. We aimed to characterize the clinical and molecular characteristics of YOCRC in patients (pts) diagnosed at our institution. Methods: Consecutive pts with a diagn
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Salmiati, Salmiati, Yustia Ningsi, and Ramlah Ramlah. "Pengaruh Penggunaan Instagram Terhadap Karakter Peserta Didik di Kelas X SMA Negeri 3 Parepare." JPPI (Jurnal Pendidikan Islam Pendekatan Interdisipliner) 3, no. 1 (2019): 73–85. http://dx.doi.org/10.36915/jpi.v3i1.53.

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The research consists of three research problems; (1) in what way is Instagram used, (2) what is the character of students, and (3) is there significant effect of Instagram toward the students’ character in class X at SMA Negeri 3 Parepare. The research applied survey research. The technique of data collection used questionnaire, interview, and observation. The population of the research involved as many as 46 class X students. The result of the research revealed (1) that the intensity of the use of Instagram by the students of class X of SMA Negeri 3 Parepare was in high category. It was show
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Martre, Anne-Marie, Virginia Danciu, and Guy Mousset. "Electroréduction de dérivés dinitrés aromatiques. III. Rôle du sulfate de titanyle comme médiateur redox." Canadian Journal of Chemistry 71, no. 8 (1993): 1136–46. http://dx.doi.org/10.1139/v93-150.

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The electrochemical behavior of titanium oxysulfate, used as a redox mediator in the reduction of 4,4′-dinitrodibenzyl, is studied in a 5 N H2SO4/EtOH 50:50 medium. The role played by electrogenerated Ti3+ ions in the chemical reduction of nitro groups is also defined. The results obtained allow the determination of the most suitable conditions leading to selective syntheses. Macroscale electrolyses at a constant potential in the presence of TiOSO4 give 4,4′-diaminodibenzyl with a great purity and a higher yield (93%) than without mediator (75%). The homogeneous chemical reduction of 4,4′-dini
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Ueberall, Michael A., Alice Eberhardt, and Gerhard H. H. Mueller-Schwefe. "Physicians Experience with and Expectations of the Safety and Tolerability of WHO-Step III Opioids for Chronic (Low) Back Pain: Post Hoc Analysis of Data from a German Cross-Sectional Physician Survey." Pain Research and Treatment 2015 (October 19, 2015): 1–8. http://dx.doi.org/10.1155/2015/745048.

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Objective. To describe physicians’ daily life experience with WHO-step III opioids in the treatment of chronic (low) back pain (CLBP). Methods. Post hoc analysis of data from a cross-sectional online survey with 4.283 Germany physicians. Results. With a reported median use in 17% of affected patients, WHO-step III opioids play a minor role in treatment of CLBP in daily practice associated with a broad spectrum of positive and negative effects. If prescribed, potent opioids were reported to show clinically relevant effects (such as ≥50% pain relief) in approximately 3 of 4 patients (median 72%)
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Jaelani, Jenal, Anita Setyowati Srie Gunarti, and Elma Yulius. "EVALUASI TEKNIS SISTEM DRAINASE DI KAWASAN KAMPUS UNIVERSITAS ISLAM “45” BEKASI." Bentang : Jurnal Teoritis dan Terapan Bidang Rekayasa Sipil 2, no. 1 (2014): 9–23. https://doi.org/10.33558/bentang.v2i1.356.

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Banjir yang terjadi di Universitas Islam “45” (UNISMA) Bekasi disebabkan oleh sistem drainase kampus yang kurang baik dan curah hujan yang tinggi serta bentuk/ kontur tanah. Lingkungan kampus yang baik merupakan kebutuhan dasar bagi para mahasiswa, dosen dan pegawainya. Tujuan dari penelitian ini adalah mencari solusi mencegah dan mengatasi banjir di UNISMA Bekasi. Penelitian ini dilakukan dengan metode observasi dan studi literatur dengan mengacu pada data primer dan data sekunder yang telah ada. Data curah hujan yang digunakan adalah data curah hujan Halim Perdana Kusuma yang di dapat dari B
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Aman, Kishor, Kumar Jwala, Ranjan Shrivastava Manish, and Anwar Zaman Zaki. "A Comparative Study of the Efficacy and Safety of 5% Minoxidil and 1 Mg Finasteride in Male Androgenetic Alopecia Patients at a Tertiary Centre in Bihar." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 1982–88. https://doi.org/10.5281/zenodo.12607392.

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<strong>Background:&nbsp;</strong>Androgenetic alopecia (AGA) is responsible for 95% of hair loss in males over 50. However, AGA is far less frequent in women, with around 40% of women experiencing some degree of hair loss, particularly after menopause. In a gradual process, alopecia is caused by the 5-reductase enzyme converting testosterone to dihydrotestosterone (DHT), which causes hair follicles to shrink.&nbsp;<strong>Aims and Objectives:&nbsp;</strong>A comparative study of the efficacy and safety of 5% minoxidil and 1 mg finasteride in male androgenetic alopecia patients.&nbsp;<strong>M
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Wier, A. T., J. S. Mink, D. J. Boethel, B. R. Leonard, and E. Burris. "Control of Soybean Loopers on Soybean, 1989." Insecticide and Acaricide Tests 16, no. 1 (1991): 229. http://dx.doi.org/10.1093/iat/16.1.229.

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Abstract Six tests were conducted to examine selected insecticides for soybean looper control. In Test I at Natchitoches, La., plots measuring 50 ft × 8 rows (36 inch row spacing) were arranged in a randomized complete block design (RCBD) with 4 replications. Insecticides were applied on 24 Aug to R6 growth stage Delta Pine 415 soybeans with a CO2-pressurized backpack sprayer calibrated to deliver 15 gal/acre at 21 psi through 8003 flat fan tips. Insecticides were evaluated by taking 2, 25 sweep samples/plot (15 inch diam sweep net) at 2 and 7 DAT. In Test II, test plots at Locust Ridge, La.,
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