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Journal articles on the topic '5-dihydro-1H-pyrazoles'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Chovatia, P. T., J. D. Akabari, P. K. Kachhadia, P. D. Zalavadia, and H. S. Joshi. "Synthesis and selective antitubercular and antimicrobial inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazole derivatives." Journal of the Serbian Chemical Society 71, no. 7 (2006): 713–20. http://dx.doi.org/10.2298/jsc0607713c.

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The new compounds 1-aryl-3-{1-phenyl-3-[p (methylthio)phenyl]pyrazol-4-yl}-2-propen-1-ones 2a?l were prepared by the condensation of 1-phenyl-3-[p (methylthio)phenyl]-4-formylpyrazole 1 with different aryl ketones. Compounds 2a?l in reaction with hydrazine hydrate yielded 3-aryl-5-{1-phenyl-3-[p-(methylthio)phenyl]pyrazol-4 yl}-4,5-dihydro-(1H)-pyrazoles 3a?l and in the presence of hydrazine hydrate in glacial acetic acid gave 1-acetyl-3-aryl 5-{1-phenyl-3-[p-(methylthio)phenyl]pyrazol-4-yl}-4,5 dihydro-(1H)-pyrazoles 4a?l. These compounds were tested in vitro for their antitubercular and anti

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2

Thirunarayanan, Ganesamoorthy, and K. Ravi. "Synthesis and Spectral Correlation Study of some 3-(3,4-dichlorophenyl)-5-(Substituted Phenyl)-4,5-dihydro-¹H-Pyrazole-1-yl-Ethanones." International Letters of Chemistry, Physics and Astronomy 19 (October 2013): 44–57. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.19.44.

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Some N-acetyl pyrazoles including 3-(3,4-dichlorophenyl)-5-(substituted phenyl)-4,5-dihydro-1H-pyrazole-1-yl-ethanones have been synthesised by solvent free cyclization cum acetylation of chalcones including substituted styryl 3,4-dichlorophenyl ketones using hydrazine hydrate and acetic anhydride in presence of catalytic amount of fly-ash: H2SO4 catalyst. The yield of these N-acetyl pyrazole derivatives are more than 75%. The synthesised N-acetyl pyrazoline derivatives were characterized by their physical constants and spectral data. The infrared spectral νC=N and C=O (cm-1) frequencies, NMR

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3

Altıntop, Mehlika Dilek. "Synthesis, In vitro and In silico Evaluation of a Series of Pyrazolines as New Anticholinesterase Agents." Letters in Drug Design & Discovery 17, no. 5 (2020): 574–84. http://dx.doi.org/10.2174/1570180816666190618111023.

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Background: Pyrazolines, electron-rich nitrogen carriers, are of great importance due to their potential applications for the treatment of many diseases including inflammation, infectious diseases and neurodegenerative disorders. Objectives: The purpose of this work was to synthesize new pyrazoline derivatives and evaluate their anticholinesterase effects. Methods: 1-Aryl-5-[4-(piperidin-1-yl)phenyl]-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazoles (1-7) were synthesized via the treatment of 1-(3,4-dimethoxyphenyl)-3-[4-(piperidin-1-yl)phenyl]prop-2- en-1-one with arylhydrazine hydrochloride d

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4

Dorn, Helmut, and R�diger Ozegowski. "LINK Synthesis with 3-Hydroxy-1H-pyrazoles: 3-Carboxyisoalkyloxy-1H-pyrazoles - bicyclic acylpyrazolium salts and ?-Lactams - 3-Carboxyisoalkyloxy-4,5-dihydro-1H-pyrazol-5-ones." Journal f�r Praktische Chemie/Chemiker-Zeitung 340, no. 5 (1998): 437–49. http://dx.doi.org/10.1002/prac.19983400506.

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5

Pasin, J. S. M., A. P. O. Ferreira, A. L. L. Saraiva, et al. "Antipyretic and antioxidant activities of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles in rats." Brazilian Journal of Medical and Biological Research 43, no. 12 (2010): 1193–202. http://dx.doi.org/10.1590/s0100-879x2010007500139.

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6

Odin, I. S., A. A. Golovanov, V. V. Bekin, and V. S. Pisareva. "Synthesis and Acylation of 3-Aryl-5-(2-phenylethynyl)-4,5-dihydro-1H-pyrazoles." Chemistry of Heterocyclic Compounds 49, no. 11 (2014): 1687–90. http://dx.doi.org/10.1007/s10593-014-1421-7.

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7

Burde, P. C., and A. M. Rahatgaonkar. "Facile Synthesis and Biological Evaluation of Cyclopropyl-Pyrazole Hybrids in [bmim][PF6]-Water Biphasic System as Antifungal Agents." Asian Journal of Organic & Medicinal Chemistry 4, no. 3 (2019): 152–58. http://dx.doi.org/10.14233/ajomc.2019.ajomc-p192.

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3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding chalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a library of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphate-water biphasic system at ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are immiscible, has been easily recycled and reused after separation of the products without any noticeable diminution in its activity.

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8

Venkata Narsimha Reddy, Chintalapani, Eligeti Rajanarendar, and Ananthula Krishnamurthy. "Synthesis of 3-methyl-1,5-diphenyl-7-aryl-7,8-dihydro-6H-pyrazolo[4,5-b]azepines." Collection of Czechoslovak Chemical Communications 55, no. 4 (1990): 1055–58. http://dx.doi.org/10.1135/cccc19901055.

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3,5-Dimethyl-4-nitro-1-phenylpyrazole (I) on treatment with chalcones II under phase transfer conditions gives the Michael adducts, 3-methyl-4-nitro-1-phenyl-5-(2-aryl-4-phenyl-4-oxo-1-butyl)pyrazoles (III). The Michale adducts on cycloreduction with stannous chloride-hydrochloric acid furnish 3-methyl-1,5-diphenyl-7-aryl-7,8-dihydro-6H-pyrazolo[4,5-b]azepines (IV). IR, 1H NMR, 13C NMR and mass spectra support the structures of III and IV.

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9

Agre, Neha, Mihir Khambete, Arundhati Maitra, et al. "Exploration of 5‐(5‐nitrothiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazoles as selective, multitargeted antimycobacterial agents." Chemical Biology & Drug Design 95, no. 1 (2019): 192–99. http://dx.doi.org/10.1111/cbdd.13624.

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10

Sviridova, L. A., A. N. Tavtorkin, N. A. Shalynina, et al. "Synthesis of 4,5-dihydro-1H-pyrazoles with chiral substituents at position 3 or 5." Russian Chemical Bulletin 64, no. 5 (2015): 1078–82. http://dx.doi.org/10.1007/s11172-015-0981-8.

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11

Pang, Wan, Shifa Zhu, Huanfeng Jiang, and Shizheng Zhu. "A novel synthesis of 5-perfluorophenyl 4,5-dihydro-1H-pyrazoles in THF or water." Journal of Fluorine Chemistry 128, no. 11 (2007): 1379–84. http://dx.doi.org/10.1016/j.jfluchem.2007.06.010.

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12

DORN, H., та R. OZEGOWSKI. "ChemInform Abstract: LINK Synthesis with 3-Hydroxy-1H-pyrazoles: 3-Carboxyisoalkyloxy-1H-pyrazoles - Bicyclic Acylpyrazolium Salts and γ-Lactams - 3-Carboxyisoalkyloxy-4,5-dihydro-1H-pyrazol-5-ones." ChemInform 29, № 46 (2010): no. http://dx.doi.org/10.1002/chin.199846136.

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13

Bharathi, R. "In vitro and molecular docking studies of an antiinflammatory scaffold with human peroxiredoxin 5 and tyrosine kinase receptor." Bioinformation 16, no. 11 (2020): 929–36. http://dx.doi.org/10.6026/97320630016929.

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A new series of 4-(3-(2-amino-3,5-dibromophenyl)-1-(4-substitutedbenzoyl)-4,5-dihydro-1H-pyrazol-5-yl)benzonitrile (4a-h) compounds were synthesized and evaluated for in-vitro anti-inflammatory activities. The spectral (IR, NMR) and elemental analyses data of the product indicated the formation of new pyrazoles 4a-h. Compound 4e exhibited potent anti-inflammatory property with 85.45 % inhibitions. This value was compared with standard diclofenac sodium. This data is explained using molecular docking analysis of receptor-ligand binding. These results demonstrated that pyrazole derivatives are p

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14

Ratković, Zoran, Jovana Muškinja, Adrijana Burmudžija, et al. "Dehydrozingerone based 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles: Synthesis, characterization and anticancer activity." Journal of Molecular Structure 1109 (April 2016): 82–88. http://dx.doi.org/10.1016/j.molstruc.2015.12.079.

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15

Odin, I. S., A. A. Golovanov, V. V. Bekin, and V. S. Pisareva. "ChemInform Abstract: Synthesis and Acylation of 3-Aryl-5-(2-phenylethynyl)-4,5-dihydro-1H-pyrazoles." ChemInform 45, no. 24 (2014): no. http://dx.doi.org/10.1002/chin.201424133.

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16

Moreira, Dayse N., Clarissa P. Frizzo, Kelvis Longhi, Nilo Zanatta, Helio G. Bonacorso, and Marcos A. P. Martins. "An efficient synthesis of 1-cyanoacetyl-5-halomethyl-4,5-dihydro-1H-pyrazoles in ionic liquid." Monatshefte für Chemie - Chemical Monthly 139, no. 9 (2008): 1049–54. http://dx.doi.org/10.1007/s00706-008-0874-8.

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17

Sauzem, Patricia D., Gabriela da S. Sant'Anna, Pablo Machado, et al. "Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats." European Journal of Pharmacology 616, no. 1-3 (2009): 91–100. http://dx.doi.org/10.1016/j.ejphar.2009.06.008.

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18

Schmidt, Arthur H., Timo Schreck, Ralf Rötz, and Sarah von Freytag-Loringhoven. "Oxokohlenstoffe und verwandte Verbindungen, 30 [1]. Über die Umsetzung von Quadratsäure mit Pyrazolinonen / Oxocarbons and Related Compounds, 30 [1]. On the Reaction of Squaric Acid with Pyrazolinones." Zeitschrift für Naturforschung B 61, no. 3 (2006): 311–19. http://dx.doi.org/10.1515/znb-2006-0311.

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Abstract Heating of squaric acid (1) with the 1-aryl-3-methyl-5-oxo-2,5-dihydro-1H-pyrazoles 3a - j and the 1,3-disubstituted pyrazolinones 7a - d in the molar ratio of 1:2 in a mixture of n-BuOH/toluene afforded the bis(pyrazolyl)-squaraines 4a - j and 8a - d, respectively. Reaction of an excess of 1 with the pyrazolinone 3j yielded 4j and the 3-hydroxy-4-pyrazolyl-cyclobutene-1,2-dione 6 as a byproduct. In contrast to disubstituted pyrazolinones, the trisubstituted pyrazolinones 9a - e reacted with squaric acid (1) to give the hydroxy-oxopyrazolyl-cyclobutenediones 10a - e.

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19

Waldo, Jesse P., Saurabh Mehta, and Richard C. Larock. "Room Temperature ICl-Induced Dehydration/Iodination of 1-Acyl-5-hydroxy-4,5-dihydro-1H-pyrazoles. A Selective Route to Substituted 1-Acyl-4-iodo-1H-pyrazoles." Journal of Organic Chemistry 73, no. 17 (2008): 6666–70. http://dx.doi.org/10.1021/jo800789p.

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20

Mitkidou, Sophia, Stelios Papadopoulos, Julia Stephanidou-Stephanatou, Aristides Terzis, and Demetrios Mentzafos. "Unusual reactions between some 1-aroyl-4,5-dihydro-4,4-dimethyl-5-methylene-1H-pyrazoles and ketenes." Journal of Organic Chemistry 55, no. 15 (1990): 4732–35. http://dx.doi.org/10.1021/jo00302a046.

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21

Buriol, Lilian, Clarissa P. Frizzo, Dayse N. Moreira, et al. "An E-factor minimized solvent-free protocol for the preparation of 4,5-dihydro-5-(trifluoromethyl)-1H-pyrazoles." Monatshefte für Chemie - Chemical Monthly 142, no. 5 (2011): 515–20. http://dx.doi.org/10.1007/s00706-011-0464-z.

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22

Dong, Heng-Shan, Yan-Fei Wang, Guo-Liang Shen, Bin Quan, and Wang-Jun Dong. "ChemInform Abstract: Synthesis of Some New 1-Acyl-5-aryl-3- (5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)-4,5-dihydro-1H-pyrazoles." ChemInform 43, no. 26 (2012): no. http://dx.doi.org/10.1002/chin.201226135.

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23

Papadopoulos, Stelios, and Julia Stephanidou-Stephanatou. "Notizen 1,3-Dipolar Cycloadditions of Benzonitrile Oxides to 1-Aroyl-4,5-dihydro-3,4,4-trimethyl-5-methylene-1H-pyrazoles." Liebigs Annalen der Chemie 1985, no. 8 (1985): 1697–703. http://dx.doi.org/10.1002/jlac.198519850815.

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24

MITKIDOU, S., S. PAPADOPOULOS, J. STEPHANIDOU-STEPHANATOU, A. TERZIS, and D. MENTZAFOS. "ChemInform Abstract: Unusual Reactions Between Some 1-Aroyl-4,5-dihydro-4,4-dimethyl-5- methylene-1H-pyrazoles and Ketenes." ChemInform 22, no. 1 (2010): no. http://dx.doi.org/10.1002/chin.199101184.

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25

Khudina, O. G., Ya V. Burgart, V. I. Saloutin, and M. A. Kravchenko. "One-pot synthesis of 5-fluoroalkyl-5-hydroxy-4-hydroxy-imino-1-isonicotinoyl-4,5-dihydro-1H-pyrazoles and their tuberculostatic activity." Russian Journal of Organic Chemistry 47, no. 6 (2011): 904–9. http://dx.doi.org/10.1134/s1070428011060121.

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26

Martins, Marcos A. P., Paulo H. Beck, Dayse N. Moreira, et al. "ChemInform Abstract: Straightforward Microwave-Assisted Synthesis of 1-Carboxymethyl-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazoles under Solvent-Free Conditions." ChemInform 41, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.201034136.

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27

Almeida da Silva, Pedro E., Daniela F. Ramos, Helio G. Bonacorso, et al. "Synthesis and in vitro antimycobacterial activity of 3-substituted 5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-1-(isonicotinoyl) pyrazoles." International Journal of Antimicrobial Agents 32, no. 2 (2008): 139–44. http://dx.doi.org/10.1016/j.ijantimicag.2008.03.019.

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28

Bertolasi, Valerio, Paola Gilli, Valeria Ferretti, Gastone Gilli, and Cristina Fernàndez-Castaño. "Self-assembly of NH-pyrazoles via intermolecular N—H...N hydrogen bonds." Acta Crystallographica Section B Structural Science 55, no. 6 (1999): 985–93. http://dx.doi.org/10.1107/s0108768199004966.

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The crystal structures of two NH-pyrazole derivatives forming intermolecular N—H...N hydrogen bonds are reported: 5-methyl-4-(3-methylpyrazol-5-yl)pyrazol-3-ol, C8H10N4O (P1), and 3-methyl-5-dihydro-1H-naphtho[1,2-d]pyrazole hemihydrochloride, C12H12N2.-C12H13N_{2}^{+}.Cl− (P2). 26 other structures are surveyed in order to obtain a deeper insight into the ways NH-pyrazoles self-assemble by means of intermolecular N—H...N hydrogen bonds in molecular crystals. A limited number of compounds form chains or dimers via homonuclear N+—H...N positive-charge-assisted hydrogen bonds, typical of proton s

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29

Singh, Nisha, Naresh K. Sangwan, and Kuldip S. Dhindsa. "Synthesis and fungitoxic activity of 5-aryl-1-formyl-4,5-dihydro-3-(2-hydroxyphenyl)-1H-pyrazoles and their complexes." Pest Management Science 56, no. 3 (2000): 284–88. http://dx.doi.org/10.1002/(sici)1526-4998(200003)56:3<284::aid-ps128>3.0.co;2-m.

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30

Buriol, Lilian, Clarissa P. Frizzo, Dayse N. Moreira, et al. "ChemInform Abstract: An E-Factor Minimized Solvent-Free Protocol for the Preparation of 4,5-Dihydro-5-(trifluoromethyl)-1H-pyrazoles." ChemInform 42, no. 38 (2011): no. http://dx.doi.org/10.1002/chin.201138118.

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31

Martins, Marcos A. P., Dayse N. Moreira, Clarissa P. Frizzo та ін. "X-ray structure, semi-empirical MO calculations and π-electron delocalization of 1-cyanoacetyl-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazoles". Journal of Molecular Structure 969, № 1-3 (2010): 111–19. http://dx.doi.org/10.1016/j.molstruc.2010.01.050.

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32

Sauzem, Patricia D., Pablo Machado, Maribel A. Rubin, et al. "Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: Novel agents with analgesic and anti-inflammatory properties." European Journal of Medicinal Chemistry 43, no. 6 (2008): 1237–47. http://dx.doi.org/10.1016/j.ejmech.2007.07.018.

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33

Chundawat, Tejpal Singh, Nutan Sharma, and Sunita Bhagat. "Synthesis and in vitro antimicrobial evaluation of novel fluorine-containing 3-benzofuran-2-yl-5-phenyl-4,5-dihydro-1H-pyrazoles and 3-benzofuran-2-yl-5-phenyl-4,5-dihydro-isoxazoles." Medicinal Chemistry Research 23, no. 3 (2013): 1350–59. http://dx.doi.org/10.1007/s00044-013-0735-9.

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34

Mitkidou, Sophia, and Julia Stephanidou-Stephanatou. "A study onm-chloroperbenzoic acid and lead tetraacetate oxidation of some 1-aroyl-4,5-dihydro-4,4-dimethyl-5-methylene-1H-pyrazoles." Journal of Heterocyclic Chemistry 28, no. 1 (1991): 49–53. http://dx.doi.org/10.1002/jhet.5570280109.

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35

Dong, Wang-Jun, Fu-Hong Cui, Zhong-Lian Gao, Rong-Shan Li, Guo-Liang Shen, and Heng-Shan Dong. "An efficient synthesis of 5-aryl-4,5-dihydro-3-(5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)-1-(4-phenylthiazol-2-yl)pyrazoles." Journal of Heterocyclic Chemistry 48, no. 5 (2011): 1154–60. http://dx.doi.org/10.1002/jhet.706.

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36

Dubovtsev, A. Yu, A. A. Moroz, M. V. Dmitriev, and A. N. Maslivets. "Reaction of methyl 3-aroyl-1-aryl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates with arylhydrazines. synthesis of isomeric 5-arylcarbamoyl-4-aroyl- and 5-aryl-4-aryloxamoyl-1H-pyrazoles." Russian Journal of Organic Chemistry 52, no. 4 (2016): 546–52. http://dx.doi.org/10.1134/s1070428016040126.

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37

Gökşen, Umut Salgın, Yelda Bingöl Alpaslan, Nesrin Gökhan Kelekçi, Şamil Işık, and Melike Ekizoğlu. "Synthesis, crystal structures and theoretical calculations of new 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-3,5-diphenyl-4,5-dihydro-(1H)-pyrazoles." Journal of Molecular Structure 1039 (May 2013): 71–83. http://dx.doi.org/10.1016/j.molstruc.2013.01.066.

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38

Bonacorso, Helio Gauze, Everton P. Pittaluga, Sydney H. Alves, et al. "Regioselective synthesis and antimicrobial evaluation of new 1-aryloxyacetyl-, 1-thiophenoyacetyl- and 1-phenylaminoacetyl-substituted 3-alkyl(aryl/heteroaryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazoles." Arkivoc 2012, no. 8 (2012): 62–75. http://dx.doi.org/10.3998/ark.5550190.0013.806.

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39

Dong, Wang-Jun, Fu-Hong Cui, Zhong-Lian Gao, Rong-Shan Li, Guo-Liang Shen, and Heng-Shan Dong. "ChemInform Abstract: An Efficient Synthesis of 5-Aryl-4,5-dihydro-3-(5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)-1- (4-phenylthiazol-2-yl)pyrazoles." ChemInform 43, no. 8 (2012): no. http://dx.doi.org/10.1002/chin.201208157.

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40

MITKIDOU, S., and J. STEPHANIDOU-STEPHANATOU. "ChemInform Abstract: A Study on m-Chloroperbenzoic Acid and Lead Tetraacetate Oxidation of Some 1-Aroyl-4,5-dihydro-4,4-dimethyl-5-methylene-1H-pyrazoles." ChemInform 22, no. 28 (2010): no. http://dx.doi.org/10.1002/chin.199128140.

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41

Bonacorso, Helio G., Ernesto S. Lang, Hilário Lewandowski, Marcos A. P. Martins, Clovis Peppe, and Nilo Zanatta. "Preparation and crystal structure determination of adducts of copper(II) chloride with 3-aryl-1-(imino-pyridin-2-yl-methyl)-5-hydroxy-5-trifluoromethyl-4,5-dihydro-1H-pyrazoles." Inorganic Chemistry Communications 6, no. 6 (2003): 646–49. http://dx.doi.org/10.1016/s1387-7003(03)00073-x.

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42

Erkin, A. V., O. S. Yuzikhin, and V. I. Krutikov. "5-Aryl-1-[pyrimidin-2(4)-yl]-3-phenyl-4,5-dihydro-1H-pyrazoles. Synthesis from substituted 2(4)-hydrazinopyrimidines and fragmentation under positive electrospray ionization." Russian Journal of Organic Chemistry 52, no. 8 (2016): 1173–78. http://dx.doi.org/10.1134/s1070428016080133.

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43

Ramírez, Juan, María Victoria Rodríguez, Jairo Quiroga, et al. "Efficient Synthesis of Novel 3-Aryl-5-(4-chloro-2-morpholinothiazol-5-yl)-4,5-dihydro-1H-pyrazoles and Their Antifungal Activity Alone and in Combination with Commercial Antifungal Agents." Archiv der Pharmazie 347, no. 8 (2014): 566–75. http://dx.doi.org/10.1002/ardp.201400084.

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44

Ben Soumane, Yahya, Abdesselam Baouid, El Mestafa El Hadrami, et al. "Synthesis, Characterization, Theoretical and Electrochemical Studies of Pyrazoline Derivatives." Mediterranean Journal of Chemistry 10, no. 9 (2020): 845. http://dx.doi.org/10.13171/mjc10902011121522ybs.

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<p class="Mabstract">The reaction of 1,3-dipolar cycloaddition of trans-anethole and three different diarylnitrilimines bearing different substituents X= {H, CH<sub>3</sub>, Cl} yield to the creation of three 1,3,4,5-tetrasubstituted pyrazoles. These reactions produce a single regioisomer. These compounds' structures were studied using diverse spectroscopic techniques such as <sup>1</sup>H, <sup>13</sup>C NMR, and HRMS. Afterwards, X-ray diffraction is performed at 5-(4-methoxyphenyl)-4-methyl-1,3-diphenyl-4,5-dihydro-1H-pyrazole. Also, Density Functio

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45

Papadopoulos, Stelios, and Julia Stephanidou-Stephanatou. "1,3-Dipolar cycloaddition reactions of nitrilimines with 1-aroyl-4,5-dihydro-3,4,4-trimethyl-5-methylene-1H-pyrazoles. Synthesis of 6-aroyl-8,9,9-trimethyl-1,2,6,7-tetrazaspiro[4.4]nona-2,7-dienes." Journal of Heterocyclic Chemistry 24, no. 2 (1987): 309–12. http://dx.doi.org/10.1002/jhet.5570240203.

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Thirunarayanan, G., and K. G. Sekar. "Solvent-free one-pot cyclization and acetylation of chalcones: Synthesis of some 1-acetyl pyrazoles and spectral correlations of 1-(3-(3,4-dimethylphenyl)-5-(substituted phenyl)-4,5-dihydro-1H-pyrazole-1-yl) ethanones." Journal of Saudi Chemical Society 20, no. 6 (2016): 661–72. http://dx.doi.org/10.1016/j.jscs.2013.12.002.

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Abdel-Wahab, Bakr F., Hatem A. Abdel-Aziz, and Essam M. Ahmed. "Synthesis and antimicrobial evaluation of 1-(benzofuran-2-yl)-4-nitro-3-arylbutan-1-ones and 3-(benzofuran-2-yl)-4,5-dihydro-5-aryl-1-[4-(aryl)-1,3-thiazol-2-yl]-1H-pyrazoles." European Journal of Medicinal Chemistry 44, no. 6 (2009): 2632–35. http://dx.doi.org/10.1016/j.ejmech.2008.09.029.

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Prešeren, Andrej, Jurij Svete, and Branko Stanovnik. "Oxidative ring-opening ofrel-(2R,3R,5S)-5-aryl-2-benzoylamino-6,7-bis(methoxycarbonyl)-2,3-dihydro-1-oxo-3-phenyl-1H,5H-pyrazolo[1,2-a]-pyrazoles. Synthesis ofrel-(2R,3R)-3-phenyl-3-[5-aryl-3,4-bis(methoxycarbonyl)pyrazolyl-1]alanine esters." Journal of Heterocyclic Chemistry 36, no. 3 (1999): 799–801. http://dx.doi.org/10.1002/jhet.5570360337.

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Preseren, Andrej, Jurij Svete, and Branko Stanovnik. "ChemInform Abstract: Oxidative Ring-Opening of rel-(2R,3R,5S)-5-Aryl-2-benzoylamino-6,7-bis (methoxycarbonyl)-2,3-dihydro-1-oxo-3-phenyl-1H,5H-pyrazolo [1,2-a]-pyrazoles. Synthesis of rel-(2R,3R)-3-Phenyl-3- [5-aryl-3,4-bis(methoxycarbonyl)pyrazolyl-1]ala." ChemInform 30, no. 43 (2010): no. http://dx.doi.org/10.1002/chin.199943190.

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Journal, Baghdad Science. "Synthesis and characterization of some heterocyclic including oxazoles,Thiazoles, Pyridazines, phthalizines and Pyrazoles with evaluating of biological activity." Baghdad Science Journal 10, no. 3 (2013): 818–27. http://dx.doi.org/10.21123/bsj.10.3.818-827.

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Abstract:

A series of new compounds including p-bromo methyl pheno acetate [2]. N-( aminocarbonyl)–p-bromo pheno acetamide [3] , N-( aminothioyl) -p-bromo phenoacetyl amide [4], N-[4-(p-di phenyl)-1,3-oxazol-2-yl]-p-bromopheno acetamide [5],N-[4-p-di phenyl]-1,3-thiazol-2-yl-p-bromo phenoacet amide [6], p-bromopheno acetic acid hydrazide [7] , 1-N-(p-bromo pheno acetyl)-1,2-dihydro-pyridazin-3,6- dione [8], 1-N-(p-bromo pheno acetyl)-1,2-dihydro-phthalazin-3,8- dione[ 9], 1-(p-bromo pheno acetyl)-3-methylpyrazol-5-one [10] and 1-(p-bromo phenol acetyl)- 3,5-dimethyl pyrazole [11] have been synthesized.

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