Academic literature on the topic '5-diketopiperazine'

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Journal articles on the topic "5-diketopiperazine"

1

Xu, Mao, Xue, et al. "Structures and Absolute Configurations of Diketopiperazine Alkaloids Chrysopiperazines A–C from the Gorgonian-Derived Penicillium chrysogenum Fungus." Marine Drugs 17, no. 5 (2019): 250. http://dx.doi.org/10.3390/md17050250.

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Three new diketopiperazine alkaloids, including two oxepine‐containing diketopiperazines, chrysopiperazines A and B (1 and 2), and one quinazoline‐containing diketopiperazine, chrysopiperazine C (5), together with three known analogues (3, 4, and 6), were isolated from the gorgonian-derived Penicillium chrysogenum fungus. The relative and absolute configurations of C-3 and C-15 in 1 and 2, C-3 and C-14 in 5 were established by NOE modified Marfey’s analysis and electronic circular dichroism (ECD) calculations. Particularly, the absolute configurations of C-19 in 1 and 3, which was very challen
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2

Pétry, Nicolas, Hafid Benakki, Eric Clot, et al. "A mechanochemical approach to access the proline–proline diketopiperazine framework." Beilstein Journal of Organic Chemistry 13 (October 19, 2017): 2169–78. http://dx.doi.org/10.3762/bjoc.13.217.

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Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides under solvent-free conditions. A deprotection–cyclization sequence yielded the corresponding diketopiperazines that were obtained with a high stereoselectivity which could be explained by DFT calculations. Using this method, an enantiopure disubstituted Pro–Pro diketopiperazine was synthesized in 4 steps, making 5 new bonds using a ball mill.
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3

Lee, Seoung Rak, Christine Beemelmanns, Leah M. M. Tsuma, Jon Clardy, Shugeng Cao, and Ki Hyun Kim. "A New Diketopiperazine, Cyclo(D-trans-Hyp-L-Leu) from a Kenyan Bacterium Bacillus licheniformis LB 8CT." Natural Product Communications 11, no. 4 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100410.

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Bacterially-produced small molecules demonstrate a wide range of structural and functional diversity. A new diketopiperazine, cyclo(D- trans-Hyp-L-Leu) (1), and five other known diketopiperazines (2–6), were isolated and purified from the fermented broth of a Kenyan bacterium Bacillus licheniformis LB 8CT. The structure of 1 was elucidated by a combination of extensive spectroscopic analyses, including 2D NMR and HR-MS, and the absolute configuration was determined by a combination of NOESY analysis and Marfey's method. The known compounds were identified as cyclo(D- cis-Hyp-L-Leu) (2), cyclo(
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4

Mohsenian Kouchaksaraee, Reza, Mahdi Moridi Farimani, Fengjie Li, Melika Nazemi, and Deniz Tasdemir. "Integrating Molecular Networking and 1H NMR Spectroscopy for Isolation of Bioactive Metabolites from the Persian Gulf Sponge Axinella sinoxea." Marine Drugs 18, no. 7 (2020): 366. http://dx.doi.org/10.3390/md18070366.

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The geographic position, highly fluctuating sea temperatures and hypersalinity make Persian Gulf an extreme environment. Although this unique environment has high biodiversity dominated by invertebrates, its potential in marine biodiscovery has largely remained untapped. Herein, we aimed at a detailed analysis of the metabolome and bioactivity profiles of the marine sponge Axinella sinoxea collected from the northeast coast of the Persian Gulf in Iran. The crude extract and its Kupchan subextracts were tested in multiple in-house bioassays, and the crude extract and its CHCl3-soluble portion s
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5

Lamm, Assaf, Igal Gozlan, Adi Rotstein, and Dror Avisar. "Detection of amoxicillin-diketopiperazine-2′, 5′ in wastewater samples." Journal of Environmental Science and Health, Part A 44, no. 14 (2009): 1512–17. http://dx.doi.org/10.1080/10934520903263306.

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6

Zhang, Geng, Zhang, et al. "Discovery of Bioactive Indole-Diketopiperazines from the Marine-Derived Fungus Penicillium brasilianum Aided by Genomic Information." Marine Drugs 17, no. 9 (2019): 514. http://dx.doi.org/10.3390/md17090514.

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Identification and analysis of the whole genome of the marine-derived fungus Penicillium brasilianum HBU-136 revealed the presence of an interesting biosynthetic gene cluster (BGC) for non-ribosomal peptide synthetases (NRPS), highly homologous to the BGCs of indole-diketopiperazine derivatives. With the aid of genomic analysis, eight indole-diketopiperazines (1−8), including three new compounds, spirotryprostatin G (1), and cyclotryprostatins F and G (2 and 3), were obtained by large-scale cultivation of the fungal strain HBU-136 using rice medium with 1.0% MgCl2. The absolute configurations
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7

Suciati and Mary J. Garson. "Isolation of the Tetrapeptide Apicidins G, H and I from the Fungus Fusarium semitectum." Natural Product Communications 9, no. 2 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900226.

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This study reports the isolation and characterization of three new tetrapeptides, apicidins G (1), H (2) and I (3), along with the known apicidin (4), apicidin A (5), apicidin C (6), diketopiperazine 7, equisetin (8) and 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (9). The structures of the new compounds were deduced by 2D NMR spectroscopic and MS data.
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8

Fu, Peng, Peipei Liu, Haijun Qu та ін. "α-Pyrones and Diketopiperazine Derivatives from the Marine-Derived Actinomycete Nocardiopsis dassonvillei HR10-5". Journal of Natural Products 74, № 10 (2011): 2219–23. http://dx.doi.org/10.1021/np200597m.

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9

Marcuccio, SM, and JA Elix. "Pyrazine Chemistry. V. Synthesis of Methylanhydropicroroccellin and Dimethylpicroroccellin." Australian Journal of Chemistry 38, no. 12 (1985): 1785. http://dx.doi.org/10.1071/ch9851785.

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The structure of the lichen diketopiperazine, picroroccellin, has been studied by the synthesis of several of its degradation products. The three possible formulations of methylanhydropicroroccellin (3), (4) and (5) were synthesized and from the physical and chemical properties, the former two compounds were shown to be dissimilar from the naturally derived material. Furthermore, the reactivity of the 3- methoxypiperazine-2,5-dione (5) entirely paralleled that reported for picroroccellin and was consistent with the oxygen functions being located at the 3- and 6-positions of the piperazine-2,5-
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10

Song, Yin-Ping, Feng-Ping Miao, Sheng-Tao Fang, Xiu-Li Yin, and Nai-Yun Ji. "Halogenated and Nonhalogenated Metabolites from the Marine-Alga-Endophytic Fungus Trichoderma asperellum cf44-2." Marine Drugs 16, no. 8 (2018): 266. http://dx.doi.org/10.3390/md16080266.

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One new bisabolane sesquiterpene, bisabolan-1,10,11-triol (1), one new norbisabolane sesquiterpene, 12-nor-11-acetoxybisabolen-3,6,7-triol (2), two new naturally occurring monoterpenes, (7S)- and (7R)-1-hydroxy-3-p-menthen-9-oic acids (3 and 4), one new naturally occurring trichodenone, dechlorotrichodenone C (5), one new chlorine-containing trichodenone, 3-hydroxytrichodenone C (6), one new diketopiperazine, methylcordysinin A (7), and one new naturally occurring oxazole derivative, 4-oxazolepropanoic acid (8), were isolated from the culture of a marine brown alga-endophytic strain (cf44-2) o
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