Relevant bibliographies by topics / 5-Hydroxyindoles

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  2. Dissertations / Theses
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Academic literature on the topic '5-Hydroxyindoles'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "5-Hydroxyindoles"

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RAGHAVENDRA, G. JOSHI, S. GADAGINAMATH GURU, and G. PUJAR BASAYYA. "Synthesis and Antimicrobial Activity of some New 4-Isogramines, 4-Arylthiomethyl and 4-Arylazo Derivatives of 5-Hydroxyindoles." Journal of Indian Chemical Society Vol. 71, April 1994 (1994): 175–78. https://doi.org/10.5281/zenodo.5894221.

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Department of Chemistry, Karnatak. University, Dharwad-580 003 <em>Manuscript received 22 March 1993. accepted 3 June 1993</em> Mannich reaction of 5-hydroxyindoles (1-10) .with formaldehyde and secondary amines produced the 4-isogramines (11-48). The nucleophilic displacement of dimethylamine from 4-dimethylaminomethyl-5-hydroxyindoles (11-15) was effected by heating them with thiophenols to get 4-arylthiomethyl-5-hydroxyindoles (49-58). The treatment of 5-hydroxyindoles (1-4 and 6-9) with aryldiazonium salt solution afforded exclusively 4-arylazo-5-hydroxyindoles (59-74). All the compounds w
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Yamazaki, Yoshimitsu, and Yasuhiro Kawano. "Inhibitory Effect of Hydroxyindoles and their Analogues on Human Melanoma Tyrosinase." Zeitschrift für Naturforschung C 65, no. 1-2 (2010): 49–54. http://dx.doi.org/10.1515/znc-2010-1-209.

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A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyindole and 11 related compounds such as 5-hydroxyindan and 6-hydroxyquinoline were tested for their inhibition of catecholase activity of tyrosinase from human HMVII melanoma cells. 6-Hydroxyindole (5) and 7-hydroxyindole (6) were potent inhibitors, while 5-hydroxyindole (4) was a weaker inhibitor than the above-mentioned compounds (IC50 = 20, 79, 366, and 342 μM for 5, 6, 4, and kojic acid, respec
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Lee, Jintae, Tarun Bansal, Arul Jayaraman, William E. Bentley, and Thomas K. Wood. "Enterohemorrhagic Escherichia coli Biofilms Are Inhibited by 7-Hydroxyindole and Stimulated by Isatin." Applied and Environmental Microbiology 73, no. 13 (2007): 4100–4109. http://dx.doi.org/10.1128/aem.00360-07.

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ABSTRACT Since indole is present at up to 500 μM in the stationary phase and is an interspecies biofilm signal (J. Lee, A. Jayaraman, and T. K. Wood, BMC Microbiol. 7:42, 2007), we investigated hydroxyindoles as biofilm signals and found them also to be nontoxic interspecies biofilm signals for enterohemorrhagic Escherichia coli O157:H7 (EHEC), E. coli K-12, and Pseudomonas aeruginosa. The genetic basis of EHEC biofilm formation was also explored, and notably, virulence genes in biofilm cells were repressed compared to those in planktonic cells. In Luria-Bertani medium (LB) on polystyrene with
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Yokoyama, Masataka, Satoshi Watanabe, and Hidekatsu Hatanaka. "Synthesis ofN-Substituted 5-Hydroxyindoles." Synthesis 1987, no. 09 (1987): 846–48. http://dx.doi.org/10.1055/s-1987-28100.

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Chirkova, Zhanna V. "SYNTHESIS OF N-HYDROXYINDOLES." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 4 (2017): 4. http://dx.doi.org/10.6060/tcct.2017604.5560.

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The basic synthetic methods for obtaining N-hydroxyindoles were studied. The first method is intramolecular reductive cyclization of ortho-substituted nitroaromatic compounds by various reducing agents. Nitrophenyl acetaldehydes (synthesis by Acheson), N,N-disubstituted amino-2-nitrostyrenes (synthesis by Somei), ortho-nitroketoetheres of different structure or 1-(o-nitroarene)-1-cyanoalkylnitroketones, ortho-nitrophenylacetonitriles were used as substrates for the synthesis of N-hydroxyindoles. Titanium chloride (III), zinc in THF solution of ammonium chloride or in acetic acid, stannous chlo
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Hanuszewska, Maria, Magdalena Prusik, and Bogdan Lewczuk. "Embryonic Ontogeny of 5-Hydroxyindoles and 5-Methoxyindoles Synthesis Pathways in the Goose Pineal Organ." International Journal of Molecular Sciences 20, no. 16 (2019): 3948. http://dx.doi.org/10.3390/ijms20163948.

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The aim of this study was to characterize the embryonic ontogeny of 5-hydroxyindoles and 5-methoxyindoles synthesis pathways in the goose pineal organ. The study was performed on embryos aged 14–28 days, which have been incubated under a 12L:12D cycle. The pineal organs were collected for measurements of indole content by HPLC every 6 h on embryonic day (ED) 14, ED 16, ED 18 and ED 22 or every 2 h on ED 24, ED 26 and ED 28. The level of tryptophan showed no significant changes during development and no day-night variations. The content of 5-hydroxytryptophan increased between ED 14 and ED 26.
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Ozaki, Yutaka, Kyouko Okamura, Ayako Hosoya, and Sang-Won Kim. "A New Approach to 5-Hydroxyindoles from 1,4-Cyclohexanedione." Chemistry Letters 26, no. 7 (1997): 679–80. http://dx.doi.org/10.1246/cl.1997.679.

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LaPorte, Matthew, Ki Bum Hong, Jie Xu, and Peter Wipf. "5-Hydroxyindoles by Intramolecular Alkynol–Furan Diels–Alder Cycloaddition." Journal of Organic Chemistry 78, no. 1 (2012): 167–74. http://dx.doi.org/10.1021/jo3022605.

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Panisheva, E. K., �. S. Krichevskii, I. S. Nikolaeva, et al. "Aminoalkyl-5- and -6-hydroxyindoles and their antiviral activity." Pharmaceutical Chemistry Journal 23, no. 2 (1989): 153–55. http://dx.doi.org/10.1007/bf00764467.

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Sharapov, Ainur D., Ramil F. Fatykhov, Igor A. Khalymbadzha, et al. "Fluorescent Pyranoindole Congeners: Synthesis and Photophysical Properties of Pyrano[3,2-f], [2,3-g], [2,3-f], and [2,3-e]Indoles." Molecules 27, no. 24 (2022): 8867. http://dx.doi.org/10.3390/molecules27248867.

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This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series. The synthesis of pyrano[3,2-f], [2,3-g], and [2,3-e]indoles involve a tandem of Bischler–Möhlau reaction of 3-aminophenol with benzoin to form 6-hydroxy- or 4-hydroxyindole followed by Pechmann condensation of these hydroxyindoles with β-ketoesters. Pyrano[2,3-f]indoles were synthesized through the Nenitzescu reaction of p-benzoquinone and ethyl aminocrotonates and subsequent Pechmann
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Dissertations / Theses on the topic "5-Hydroxyindoles"

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Němečková, Anna. "Voltametrické a amperometrické stanovení homovanilové, vanilmandlové a 5-hydroxy-3-indoloctové kyseliny." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-434498.

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Presented dissertation thesis is focused on the development of electrochemical methods for the determination of three important tumour biomarkers, namely homovanillic acid (HVA), vanillylmandelic acid (VMA), and 5-hydroxyindole-3-acetic acid (5-HIAA). First part of the study is focused on electrochemical behaviour of these analytes in batch arrangement using differential pulse voltammetry (DPV) at screen-printed carbon electrodes (SPCEs). It has been proved that presented method is sufficiently sensitive for monitoring above mentioned analytes. Moreover, it can be used for determination of HVA
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Book chapters on the topic "5-Hydroxyindoles"

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Iizuka, Hideaki, Takayuki Ishige, Yuri Ohta, and Takehiko Yajima. "Simultaneous Determination of 5-Hydroxyindoles and Catecholamines by Hplc with Fluorometric Precolumn Derivatization." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4709-9_104.

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Moroni, Flavio, Raffaella Carpenedo, Guido Mannaioni, et al. "Studies on the Pharmacological Properties of Oxindole (2-Hydroxyindole) and 5-Hydroxyindole: Are They Involved in Hepatic Encephalopathy?" In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5945-0_4.

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Winkelmann, Jochen. "Diffusion coefficient of 5-hydroxyindole-3-acetic acid in water." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_709.

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Davison, A. S., B. Norman, A. M. Milan, et al. "Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment." In JIMD Reports. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/8904_2017_72.

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"Nenitzescu 5-Hydroxyindole Synthesis." In Indole Ring Synthesis. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118695692.ch15.

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Spiegelaar, Nicole, and Sebastian Warma. "Insulin Impairment Disrupts Central Serotonin Synthesis: Implications for Stress Resilience." In Serotonin - Neurotransmitter and Hormone of Brain, Bowels and Blood [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1004045.

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This chapter reviews the important neurophysiological mechanisms that drive symptoms characteristic of comorbid depression and metabolic disease. It outlines how insulin impairment in the periphery1 interferes with central 5-hydroxyindole metabolism and ultimately restricts central2 serotonin synthesis. More specifically, peripheral insulin impairment disrupts i) peripheral and central tryptophan stores, ii) tryptophan uptake into the brain, and iii) tryptophan hydroxylase-2 function. Central serotonin availability appears to be increasingly restricted by higher degree and duration of insulin
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Lambert, Tristan H. "Synthesis of Heteroaromatics." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0069.

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Peter Wipf at the University of Pittsburgh utilized (J. Org. Chem. 2013, 78, 167) an alkynol-furan Diels-Alder reaction to convert 1 into the hydroxyindole 2. An intramolecular Larock indole synthesis was employed (Angew. Chem. Int. Ed. 2013, 52, 4902) by Yanxing Jia at Peking University for the conversion of aniline 3 to tricyclic indole 4. The reaction of boronodiene 5 with nitrosobenzene to produce pyrrole 6 was reported (Chem. Commun. 2013, 49, 5414) by Bertrand Carboni at CNRS University of Rennes and Andrew Whiting at Durham University. The merger of imine 7 with propargyl amine 8 in the
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