Academic literature on the topic '5]imidazo[1'

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Journal articles on the topic "5]imidazo[1"

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Slyvka, N. Yu, L. M. Saliyeva, M. B. Litvinchuk, A. M. Grozav, N. D. Yakovychuk, and M. V. Vovk. "Regioselective synthesis of new (imidazo[2,1-b] [1,3]-thiazin-6-yl)-1,2,3-triazole-5-carboxylates as potential antimicrobial agents." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 5 (October 2023): 114–22. http://dx.doi.org/10.32434/0321-4095-2023-150-5-114-122.

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The paper presents the results of the study on the interaction of azido(benz)imidazo[2,1-b][1,3]thiazines with acetylene carboxylates under non-catalytic conditions according to Huguesgen. It was established that the [3+2]-cyclocondensation of the specified reagents occurs regioselectively upon heating and without the use of a catalyst with the formation of a 1,4-addition product, alkyl 1-((benzo)imidazo[2,1-b][1,3]thiazine-6-yl)-1H-1,2,3-triazole-5-carboxylates 4a–g, the structure of which was thoroughly proved by the methods of 1H (13C) NMR spectroscopy and chromatography-mass spectrometry.
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Shukla, Upendra K., Raieshwar Singh, J. M. Khanna, et al. "Synthesis of trans-2-[N-(2-Hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)]iminothiazolidine and Related Compounds - A New Class of Antidepressants." Collection of Czechoslovak Chemical Communications 57, no. 2 (1992): 415–24. http://dx.doi.org/10.1135/cccc19920415.

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Antiparasitic and antidepressant activities exhibited by tetramisole (I) and its enantiomers prompted the study of its structural analogs trans-2-[N-(2-hydroxy-1,2,3,4-tetrahydronaphthalene/indane-1-yl)]iminothiazolidine (VIII/IX) and 2,3,4a,5,6,10b-hexahydronaphtho[1',2':4,5]-imidazo[2,1-b]thiazole (XII), 2,3,4a,5-tetrahydro-9bH-indeno[1',2':4,5]imidazo[2,1-b]thiazole (XIII), and 2,3,4a,5-tetrahydro-9bH-indeno[1',2':4,5]imidazo[2,1-b]thiazole (XVI), and a homolog 3,4,6,7-tetrahydro-7-phenyl-2H-imidazo[2,1-b]-1,3-thiazine (XX). While none of these compounds showed any noteworthy antiparasitic
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Bori, Jugal, Nibedita Behera, Satyajit Mahata, and Vadivelu Manivannan. "Synthesis of Imidazo[5, 1-a ]isoquinoline and Its 3-Substituted Analogues Including the Fluorescent 3-(1-Isoquinolinyl)imidazo[5, 1-a ]isoquinoline." ChemistrySelect 2, no. 35 (2017): 11727–31. http://dx.doi.org/10.1002/slct.201702420.

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JAG, MOHAN, S. R. ANJANBYULU G., and KIRAN. "Heterocyclic Systems containing Bridgehead Nitrogen Atom. Synthesis of Thiadiazolo[2′,3′: 2,1]imidazo[4,5-b]quinoxaline, Iiniclazo[2, 1 -1)]-1,3,4-thiadiazoles and their Brominated Products." Journal of Indian Chemical Society Vol. 66, Feb 1989 (1989): 118–19. https://doi.org/10.5281/zenodo.5959418.

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Department of Chemistry, Maharshi Dayanaud University, Rohtak-121 001 <em>Manuscript received 28 March 1988, accepted 2 November 1988</em> <strong>2-Amino-5-alkylthiadiazoles (1) condense with\(\propto\)-haloketones and 2,3-dichioro&shy;</strong><strong>quinoxalene to furnish respectively the cyclised </strong><strong>products, 2,6-disubstituted imidazo [2,1-b]-1,3,4-thiadiezoles (2) </strong><strong>and 2-substituted-thiadiazolo2</strong><strong>ʹ</strong><strong>,3</strong><strong><sup>&prime;</sup></strong><strong> : 2,1]imidazo[4,5-b</strong><strong>ʹ</strong><strong>- quinoxaline (4). Bro
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Demchenko, Sergii, Sergii Yarmoluk, Volodymyr Sukhovieiev, Oleksandr Golovchenko, Oleksandr Sukhovieiev, and Anatolii Demchenko. "Syntheses and evaluation of novel 3-hydroxy-1,3-diaryl-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromides as potential anticancer agents." Pharmacia 71 (November 27, 2024): 1–10. http://dx.doi.org/10.3897/pharmacia.71.e135992.

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New 3-hydroxy-1,3-diaryl-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromides have been designed, synthesized, and characterized by 1Н NMR, 13C NMR, and LCMS. The cyclic structure of the condensation products of aryl-(3,4,5,6-tetahydropyridin-2-yl)amines with α-bromoketones has been proven. It has been shown that heating 3-hydroxy-1,3-bis-(41-methoxyphenyl)-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromide in acetic anhydride accompanied by elimination of water to form 1,3-bis-(41-methoxyphenyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine-1-ium bromide. Antitumor activity of 1,3-
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Demchenko, Sergii, Sergii Yarmoluk, Volodymyr Sukhovieiev, Oleksandr Golovchenko, Oleksandr Sukhovieiev, and Anatolii Demchenko. "Syntheses and evaluation of novel 3-hydroxy-1,3-diaryl-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromides as potential anticancer agents." Pharmacia 71 (November 27, 2024): 1–10. https://doi.org/10.3897/pharmacia.71.e135992.

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New 3-hydroxy-1,3-diaryl-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromides have been designed, synthesized, and characterized by 1Н NMR, 13C NMR, and LCMS. The cyclic structure of the condensation products of aryl-(3,4,5,6-tetahydropyridin-2-yl)amines with α-bromoketones has been proven. It has been shown that heating 3-hydroxy-1,3-bis-(41-methoxyphenyl)-2,3,5,6,7,8-hexahydro-imidazo[1,2-a]pyridine-1-ium bromide in acetic anhydride accompanied by elimination of water to form 1,3-bis-(41-methoxyphenyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine-1-ium bromide. Antitumor activity of 1,3-
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JAG, MOHAN, S. R. ANJANBYULU G., and KIRAN. "Heterocyclic Systems containing Bridgehead Nitrogen Atom. Synthesis of Thiadiazolo[2',3', : 2,1 )imidazo[ 4,5-b)quinoxaline, Jmidazo[2,1-b ]-1,3,4-thiadiazoles and their Brominated Products." Journal of Indian Chemical Society Vol. 66, Feb 1989 (1989): 118–19. https://doi.org/10.5281/zenodo.6303535.

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Department of Chemistry, Maharshi Dayanand University, Rohtak-124&nbsp;001 <em>Manuscript received 25 March 1988, accepted 2 November 1988</em> 2-Amino-5-alkylthiadiazoles (1) condense with \(\propto\)-haloketones and 2,3-dichloroquinoxalene to furnish&nbsp;respectively the cyclised products, 2,6-disubstituted imidazo [2,1-b]-1,3,4-thiadiazoles (2) and 2-substituted-thiadiazolo(2<em>&#39;,</em>3<em>&#39;</em>: 2,1] imidazo[4,5-b]- quinoxaline (4). Bromination of 2 furnishes 5-bromo-2,6-disubstituted-imidazo[2,1-b]- thiadiazoles (3). The antimicrobial activities of some of the compounds have be
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Kubík, Richard, Stanislav Böhm, Iveta Ruppertová, and Josef Kuthan. "Sterically Crowded Heterocycles. III. A General Approach to Imidazo[1,2-a]pyridines by Ferricyanide Oxidation of Quaternary Pyridinium Salts." Collection of Czechoslovak Chemical Communications 61, no. 1 (1996): 126–38. http://dx.doi.org/10.1135/cccc19960126.

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Substituted 1-(pyridin-2-yl)-2,4,6-triphenylpyridinium perchlorates 1b-1e were converted with potassium ferricyanide and potassium hydroxide to sterically crowded 2-phenyl-3-[(Z)-1,3-diphenyl-3-oxopropenyl]imidazo[1,2-a]pyridines 2b-2e accompanied by minor isomeric 2-benzoyl-3,5-diphenyl-1-(pyridin-2-yl)pyrroles 3c-3e. 4-Phenyl-2,6-di(4-substituted phenyl)-1-(pyridin-2-yl)pyridinium salts 4a, 4b gave exclusively corresponding imidazo[1,2-a]pyridines 5a, 5b while the ferricyanide oxidation of 1-(5-iodo- and 5-cyanopyridin-2-yl)-2,4,6-triphenylpyridinium perchlorates 6a, 6b led to mixtures of ma
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JAG, MOHAN, S. R. ANJANBYULU G. та KIRAN. "Heterocyclic Systems containing Bridgehead Nitrogen Atom. Synthesis of Thiadiazolo[2ʹ3′: 2,1]imidazo[4,5-b]quinoxaline, Iiniclazo[2, 1 -b)]-1,3,4-thiadiazoles and their Brominated Products". Journal of Indian Chemical Society Vol. 66, Feb 1989 (1989): 118–19. https://doi.org/10.5281/zenodo.5995035.

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Department of Chemistry, Maharshi Dayanaud University, Rohtak-121 001 <em>Manuscript received 28 March 1988, accepted 2 November 1988</em> <strong>2-Amino-5-alkylthiadiazoles (1) condense with \(\propto\)-haloketones and 2,3-dichioro&shy;</strong><strong>quinoxalene to furnish respectively the cyclised </strong><strong>products, 2,6-disubstituted imidazo [2,1-b]-1,3,4-thiadiezoles (2) </strong><strong>and 2-substituted-thiadiazolo[2</strong><strong>ʹ</strong><strong>,3</strong><strong><sup>&prime;</sup></strong><strong> : 2,1]imidazo[4,5-b<sup>1</sup>- quinoxaline (4). Bromination of 2 </stron
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Semwal, Rashmi, Gaurav Badhani, and Subbarayappa Adimurthy. "Pd-catalyzed annulation of imidazo[1,2-a]pyridines with coumarins and indoles: synthesis of benzofuran and indole fused heterocycles." Chemical Communications 58, no. 10 (2022): 1585–88. http://dx.doi.org/10.1039/d1cc06803b.

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Palladium-catalyzed annulation of 2-arylimidazo[1,2-a]pyridines for the synthesis of benzofuro[3,2-a]imidazo[5,1,2-cd]indolizines and 6-methyl-6H-imidazo[5′,1′,2′:3,4,5]indolizino[1,2-b]indoles with coumarins and N-methyl indoles has been described.
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Dissertations / Theses on the topic "5]imidazo[1"

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Tber, Zahira. "L'imidazo[1,2-a]pyridine : fonctionnalisation et synthèse des nouveaux polyhétérocycles." Thesis, Orléans, 2016. http://www.theses.fr/2016ORLE2021.

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Les préparations de composés comportant un noyau imidazo[1,2-a]pyridinique constituent un thème de recherche important en synthèse organique, compte tenu des nombreuses activités biologiques qu’ils peuvent présenter. Dans la première partie, nous nous sommes concentrés sur le développement de nouvelles stratégies rapides et efficaces basées sur l’utilisation de cuivre et de fer pour fonctionnaliser la position 6 du cycle imidazo[1,2-a]pyridine avec diverses amines et divers thiols. Ensuite, nous avons appliqué avec succès cette procédure pour la préparation de thioéthers symétriques et dissymé
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Bou, Karroum Nour. "Synthèse et développement de nouvelles molécules hétérocycliques tricycliques : étude de leurs propriétés immunomodulatrices." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTT014/document.

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Les récepteurs Toll-like 7 et 8 jouent un rôle important dans l’activation de la réponse immunitaire innée et adaptative. Leur stimulation conduit à la production des cytokines pro-inflammatoires et d’interférons de type I. L’imiquimod et son dérivé le résiquimod sont les premières molécules de faible poids moléculaire décrites comme agonistes du TLR7 et TLR8. Ces deux molécules ont montré des activités anticancéreuses et adjuvantes très importantes. Récemment, les TLR 7 et 8 ont fait l’objet de plusieurs publications visant à développer de nouveaux agonistes TLR7 et/ou TLR8 dans la perspectiv
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Nordqvist, Anneli. "Hit Identification and Hit Expansion in Antituberculosis Drug Discovery : Design and Synthesis of Glutamine Synthetase and 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors." Doctoral thesis, Uppsala universitet, Avdelningen för organisk farmaceutisk kemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-155428.

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Since the discovery of Mycobacterium tuberculosis (Mtb) as the bacterial agent causing tuberculosis, the permanent eradication of this disease has proven challenging. Although a number of drugs exist for the treatment of tuberculosis, 1.7 million people still die every year from this infection. The current treatment regimen involves lengthy combination therapy with four different drugs in an effort to combat the development of resistance. However, multidrug-resistant and extensively drug-resistant strains are emerging in all parts of the world. Therefore, new drugs effective in the treatment o
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Ye, Tzuen-Yang, and 葉尊揚. "Copper-Catalysed Aerobic Oxidative Carbocyclization- Ketonization, One-Pot Synthesis of Imidazo[1,2-a]benzimidazole and 1H-pyrrol-1-yl-1H-benzo[d]imidazole-5-carboxylate." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/73013471742307853416.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>104<br>This thesis is divided into three parts, the first part is copper-catalysed aerobic oxidative carbocyclization- ketonization, one-pot synthesis of imidazo[1,2-a]benzimidazole, the second part is a single copper-catalysed aerobic oxidative carbocyclization- ketonization, one-pot synthesis of 1H-pyrrol-1-yl-1H-benzo [d] imidazole-5-carboxylates, the third part is a synthetic Rosoxacin. Part 1: Two copper metal-catalyzed alkyne-terminal addition to the imine derived from 2-aminobenzimidazole with an aromatic aldehyde formed in an oxygen system and accompanied b
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Book chapters on the topic "5]imidazo[1"

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"2,3,6,8,9,10,12,13-Octahydro-1H,5H-imidazo[1,2-d]imidazo[2',1:7,1][1,4]diazepino[6,5-f][1,4]diazepine (18) to 26,27-dinor-Cholest-5-ene (17)." In Substance Index Cyclic Compounds VIII, Polycyclic Compounds I, edited by Backes, Fröhlich, and Padeken. Georg Thieme Verlag, 2001. http://dx.doi.org/10.1055/b-0035-114399.

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Conference papers on the topic "5]imidazo[1"

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Nikhila, G. R., S. R. Batakurki, and B. C. Yallur. "Synthesis, characterization and antioxidant studies of benzo[4, 5]imidazo[2, 1-b]thiazole derivatives." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON ADVANCES IN MATERIALS RESEARCH (ICAMR - 2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0023101.

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Hosmane, Ramachandra, та Huan-Ming Chen. "Synthesis of 1-(2'-Deoxy-γ-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5 H,6H)-dion: a Potentially Beneficial Building Block for Antisense Applications". У The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01926.

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Marbello, O. D., A. G. Pelosi, L. H. Z. Cocca, et al. "Analysis of the nonlinear optical response in Imidazo[4,5-b]Pyridine derivatives." In Latin America Optics and Photonics Conference. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.w4a.1.

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In this work, the linear and nonlinear optical properties of three Imidazo[4-5,b]pyridine derivatives were investigated The results show an increase in the fluorescence quantum efficiency and 2PA cross-section due to substituent groups.
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