Relevant bibliographies by topics / 5-methylTHF

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic '5-methylTHF'

Author: Grafiati
Published: 11 March 2023

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Journal articles on the topic "5-methylTHF"

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Palmer, Ashley M., Elena Kamynina, Martha S. Field, and Patrick J. Stover. "Folate rescues vitamin B12 depletion-induced inhibition of nuclear thymidylate biosynthesis and genome instability." Proceedings of the National Academy of Sciences 114, no. 20 (2017): E4095—E4102. http://dx.doi.org/10.1073/pnas.1619582114.

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Clinical vitamin B12 deficiency can result in megaloblastic anemia, which results from the inhibition of DNA synthesis by trapping folate cofactors in the form of 5-methyltetrahydrofolate (5-methylTHF) and subsequent inhibition of de novo thymidylate (dTMP) biosynthesis. In the cytosol, vitamin B12 functions in the remethylation of homocysteine to methionine, which regenerates THF from 5-methylTHF. In the nucleus, THF is required for de novo dTMP biosynthesis, but it is not understood how 5-methylTHF accumulation in the cytosol impairs nuclear dTMP biosynthesis. The impact of vitamin B12 deple
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Pfeiffer, Christine M., Maya R. Sternberg, Zia Fazili, et al. "Folate status and concentrations of serum folate forms in the US population: National Health and Nutrition Examination Survey 2011–2." British Journal of Nutrition 113, no. 12 (2015): 1965–77. http://dx.doi.org/10.1017/s0007114515001142.

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Serum and erythrocyte (RBC) total folate are indicators of folate status. No nationally representative population data exist for folate forms. We measured the serum folate forms (5-methyltetrahydrofolate (5-methylTHF), unmetabolised folic acid (UMFA), non-methyl folate (sum of tetrahydrofolate (THF), 5-formyltetrahydrofolate (5-formylTHF), 5,10-methenyltetrahydrofolate (5,10-methenylTHF)) and MeFox (5-methylTHF oxidation product)) by HPLC–MS/MS and RBC total folate by microbiologic assay in US population ≥ 1 year (n approximately 7500) participating in the National Health and Nutrition Examina
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Taflin, Helena, Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, and Kristoffer Derwinger. "Folate Levels and Polymorphisms in the Genes MTHFR, MTR, and TS in Colorectal Cancer." Clinical Medicine Insights: Oncology 8 (January 2014): CMO.S12701. http://dx.doi.org/10.4137/cmo.s12701.

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Aim The aim of the study was to explore and describe the effect of polymorphisms in folate-associated genes regarding the levels of different folate forms and their distribution in tumors and mucosa in patients with colorectal cancer. Materials and Methods Tumor and mucosa tissues from 53 patients with colorectal cancer were analyzed. The concentrations of tetrahydrofolate (THF), 5-methylTHF, and 5,10-methyleneTHF were measured by liquid chromatography—mass spectrometry. Genotyping of polymorphisms in the folate-associated genes methylenetetrahydrofolate reductase ( MTHFR, C677T), methionine s
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Dattilo, Maurizio, Carolina Fontanarosa, Michele Spinelli, Vittorio Bini, and Angela Amoresano. "Modulation of Human Hydrogen Sulfide Metabolism by Micronutrients, Preliminary Data." Nutrition and Metabolic Insights 15 (January 2022): 117863882110653. http://dx.doi.org/10.1177/11786388211065372.

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Background: Hydrogen sulfide (H2S) is a pivotal gasotransmitter networking with nitric oxide (NO) and carbon monoxide (CO) to regulate basic homeostatic functions. It is released by the alternative pathways of transulfuration by the enzymes Cystathionine Beta Synthase (CBS) and Cystathionine Gamma Lyase (CSE), and by Cysteine AminoTransferase (CAT)/ 3-Mercaptopyruvate Sulfur Transferase (3MPST). A non-enzymatic, intravascular release is also in place. We retrospectively investigated the possibility to modulate the endogenous H2S release and signaling in humans by a dietary manipulation with su
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Mosnier, Hannah, Erin Kelly, Kamaya Lawrence, et al. "The Role of One-Carbon Metabolism After Ischemic Stroke in an Aged Mouse Model." Current Developments in Nutrition 4, Supplement_2 (2020): 1226. http://dx.doi.org/10.1093/cdn/nzaa057_042.

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Abstract Objectives Nutrition is a modifiable risk factor for stroke, which is one of the leading causes of death and disability world-wide. In humans deficiencies in one-carbon metabolism, including the methyltetrahydrofolate reductase (MTHFR) polymorphism, have been linked to increased risk of stroke. The Mthfr+/− mice mouse model mimics the phenotype of the MTHFR677C – >T polymorphism. In our work using in vitro and in vivo models of ischemic stroke we have observed decreased recovery after stroke through reduced neuronal and astrocyte viability and increased apoptosis in MTHFR-defic
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Sufrin, Janice R., Arthur J. Spiess, Debora L. Kramer, et al. "Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogs of 5'-deoxy-5'-(methylthio)adenosine." Journal of Medicinal Chemistry 34, no. 8 (1991): 2600–2606. http://dx.doi.org/10.1021/jm00112a039.

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SUFRIN, J. R., A. J. SPIESS, D. L. KRAMER, et al. "ChemInform Abstract: Targeting 5′-Epoxy-5′-(methylthio)adenosine Phosphorylase by 5′-Haloalkyl Analogues of 5′-Deoxy-5′-(methylthio)adenosine." ChemInform 23, no. 2 (2010): no. http://dx.doi.org/10.1002/chin.199202319.

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Alam, L. V., R. V. Kharbash, and G. I. Koldobskii. "2-Substituted 5-methylthio- and 5-methylsulfonyltetrazoles." Russian Journal of Electrochemistry 36, no. 6 (2000): 916–18. http://dx.doi.org/10.1007/bf02757456.

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Yu-Xiu, Liu, Cui Ming-Bo, Zhao Qi-Qi, Wang Qing-Min, Liu Ying, and Huang Run-Qiu. "Reduction of Pyrimidine Derivatives by LiAlH4." Journal of Chemical Research 2007, no. 8 (2007): 490–93. http://dx.doi.org/10.3184/030823407x240872.

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The reduction of ethyl 2-methylthio-(or 2-ethoxy)pyrimidine-5-carboxylate by LiAlH4 afforded ethyl 2-methylthio-(or 2-ethoxy)-1,6-dihydropyrimidine-5-carboxylate as the main product. Similarly, the reduction of 2-methylthio-(or 2-methoxy)pyrimidine-5-carboxamide by LiAlH4 gave 2-methylthio-(or 2-methoxy)-1,6-dihydropyrimidine-5-carbonitrile as main product.
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Singh, Okram Mukherjee, H. Junjappa, and H. Ila. "A Facile Synthesis of 3-Cyclopropyl- and 5-Cyclopropyl-isoxazoles." Journal of Chemical Research 23, no. 6 (1999): 398–99. http://dx.doi.org/10.1177/174751989902300627.

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Dissertations / Theses on the topic "5-methylTHF"

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GOMES, DE LIMA LUIS CARLOS. "Reactions d'alcynes cyanes (monocyanoacethylene et dicyanoacethylene), vis-a-vis de complexes organometalliques du fer, du cobalt, du molybdene et du tungstene." Brest, 1986. http://www.theses.fr/1986BRES2009.

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Etude de la reactivite de complexes thiolates du fer et du tungstene (cp(co)::(n) m(sch::(3))) vis a vis du mono et du dicyanoacetylene. Aptitude des complexes de co(i) a intervenir dans la formation de molecules organiques. Nature des liaisons m-pb(m=mo ou w) dans les complexes cp(co)::(3)m-pbr::(3) et (cp(co)::(3)m)::(2) pbr::(2). Donnes de rmn de **(95)mo et **(207)pb
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FRISO, Simonetta. "GENE-NUTRIENT INTERACTIONS AND EPIGENETICS. BIOCHEMICAL BASES OF THE ROLE OF PLASMA AND RED BLOOD CELL FOLATE, THE MTHFR C677T POLYMORPHISM AND GENOMIC DNA METHYLATION." Doctoral thesis, 2002. http://hdl.handle.net/11562/364225.

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La metilazione del DNA, una caratteristica epigenetica essenziale del DNA che modula l'espressione genica e l'integrità del genoma, è catalizzata da metiltrasferasi che utilizzano la S-adenosilmetionina (SAM) quale donatore universale di gruppi metilici. L'enzima metilenetetraidrofolato reduttasi (MTHFR) catalizza la sintesi del 5-metiltetraidrofolato (5-methylTHF), il donatore di gruppi metilici per la sintesi di metionina dall'omocisteina e precursore della SAM. Nel presente studio si è voluto determinare l'effetto dello status dei folati sulla metilazione genomica del DNA con particolare en
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Book chapters on the topic "5-methylTHF"

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Dombek, R. Duane, Robert J. Angelici, Ian S. Butler, and Daniel Cozak. "Dicarbonyl(η5 -Cyclopentadienylxthio-Carbonyl)Iron(1 +) Hexafluorophosphate(1 -) and Dicarbonyl(η 5 -Cyclopentadienyl)-[(Methylthio)Thiocarbonyl]Iron." In Inorganic Syntheses. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132487.ch29.

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Conference papers on the topic "5-methylTHF"

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Bosshard, Christian, Pan Feng, Man Shing Wong, Martin Bösch, Urs Meier, and Peter Günter. "Thiophene Based Hydrazones: a New Class of Nonlinear Optical Molecular Crystals." In Organic Thin Films for Photonic Applications. Optica Publishing Group, 1997. http://dx.doi.org/10.1364/otfa.1997.thd.2.

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Crystalline solids are often regarded as the best choice of material form for practical use as optical frequency converters because of the excellent long-term orientational stability and extremely high density of active components. Such materials can be combined with inexpensive diode lasers for optic parametric generation of a broad range of optical frequencies [1, 2]. We here report on our on-going efforts in the development of novel and highly efficient second-order nonlinear optical crystalline materials for frequency conversion, based on the hydrazone derivatives 5-(methylthio)-thiophenec
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Żołnowska, Beata, Jarosław Sławiński, and Anna Kawiak. "Synthesis of New N-Substituted N′-(2-methylthio-4-chloro-5-methylbenzenesulfonyl)guanidines with Anticancer Activity." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13255.

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Lyapustin, D. N., E. N. Ulomsky, E. K. Voinkov, and V. L. Rusinov. "Preparation of new 5-methylthio-6-nitro-1,2,4-triazolo[1,5-a]pyrimidine-7-ones as structural analogues of antiviral drugs." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087320.

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Smit, Biljana, Petar Stanic, and Marija Zivkovic. "Synthesis, characterization and an extensive biological evaluation of 5-​[2-​(methylthio)​ethyl]​-​3-​(2-​propen-​1-​yl)​-​2-​thioxo-4-​imidazolidinone." In 4th International Electronic Conference on Medicinal Chemistry. MDPI, 2018. http://dx.doi.org/10.3390/ecmc-4-05625.

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Sohrabi, Beheshteh, Mehdi Kiasadegh, and Javad Beheshtian. "Computational Studies of Optical Properties of (E)-2-(5-methacrylamido-2, 3-bis (methylthio) phenyl) Diazenesulfonate Dye for Solar Cell Using DFT and TD-DFT Methods." In The 16th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2012. http://dx.doi.org/10.3390/ecsoc-16-01158.

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