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Dissertations / Theses on the topic '5-one'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kalu, Chimdi, Austin Miller, and Abbas G. Shilabin. "SYNTHESIS AND BIOLOGICAL SIGNIFICANCE OF 1,2,4-OXADIAXOLIDIN-5-ONE." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/121.

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SYNTHESIS AND BILOGICAL SIGNIFICANCE OF 1,2,4-OXADIAXOLIDIN-5-ONE Chimdi kalu, Austin Miller and Dr. Abbas G. Shilabin Department of Chemistry, East Tennessee State University, Johnson City, TN 37614. ABSRTACT Due to the challenge posed by microbial resistance to broad spectrum of antibiotics, there has been a great need to synthesize of a novel compound which has a different mechanism of action on microbial activity. 1,2,4-oxadiaxolidin-5-One constitute an important class of compound with tremendous potential as pharmaceutical and otherwise biologically relevance substance due to the fact th

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2

Gumz, Thorsten. "5-Alkylidenthiophen-2-one aus 5-Phenoxythien-2-ylcarbinolen ein Beitrag zu Synthese und biologischen Eigenschaften /." [S.l. : s.n.], 1999. http://www.sub.uni-hamburg.de/disse/38/gumzdiss.pdf.

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3

Dhami, Archana. "Approaches to new DNA-repair inhibitors for applications in cancer therapy." Thesis, University of Bath, 2008. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512320.

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5-Aminoisoquinolin-1(2H)-one hydrochloride (5-AIQ.HCI) is a potent, water-soluble PARP-1 inhibitor that exhibits outstanding activity in a wide range of disease models in vivo. The aim of this project is the design and synthesis of derivatives with substituents at the 4-positoin of 5-AIQ. The modes of cyclisation of methyl 2-(substituted)alkynyl-3-nitrobenzoates with different electrophiles (ICI, PhSeCI, HgSO4) were studied. The exclusive formation of isocoumarins demonstrates the influence of the nitro group in directing electrophile-driven cyclisations towards the 6-endo-dig mode. The crysta

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Partlett, N. K. "The synthetic utility of 5-O-hydroxymethyl-(5H)-furan-2-one." Thesis, University of Reading, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233186.

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5

Wilkerson, Crystal Lynn. "Perceptions of School Leaders for One-to-One Device Implementation in K-5 Elementary Schools in One Division in Virginia." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/85262.

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New initiatives involving the use and implementation of technology are being put into place in many school systems across the country to help students acquire needed 21st century skills (Grady, 2011). The purpose of this study of the implementation of one-to-one devices was to examine school leaders' perceptions of changes in their leadership practices, teachers' instructional practices, and student engagement. A member of the central office staff and five elementary principals were asked to provide perceptions on the implementation process with their staff. School leaders also provided per

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Karmakar, S. "Synthetic studies towards pseudotheonamides, herbarium III, bicyclic thiohydantoins and oxazolidinone -5- one." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2006. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2479.

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7

Conde, Amanda Solis. "Synthesis of 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one derivatives by electrophilic aromatic substitution." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1547584724393162.

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8

Akuche, Christiana Ifeyinwa. "A novel antibacterial agent by design, 2-carboxymethyl-5-hydroxy-1,2-oxazin-3-one." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/mq24079.pdf.

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9

Schroer, Hunter William. "Biotransformation and photolysis of 2,4-dinitroanisole, 3-nitro-1,2,4-triazol-5-one, and nitroguanidine." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6274.

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Nitroaromatic explosives have contaminated millions of acres of soil and water across the globe since World War II with known mutagenic, carcinogenic, and ecotoxicological effects. Recently, the U.S. Army initiated a shift away from traditional explosive compounds, such as trinitrotoluene (TNT) and hexahydrotrinitrotriazine (RDX), towards new, insensitive high explosive formulations. The new formulations approved for use include “IMX-101” and “IMX-104,” which contain 2,4-dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine (NQ). These mixtures are less prone to accident

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10

Symer, Maryellen. "One-to-One Technology Device Integration in Grades 3-5 and the Beliefs & Actions of Teachers and District-Level Leaders." Thesis, Sage Graduate School, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=10981820.

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<p> One-to-One Technology Device Integration in Grades 3-5 and the Beliefs & Actions of Teachers and District-Level Leaders One-to-One technology initiatives began in the 1990’s and have expanded over time. It is not about distributing devices but rather how those devices transform teaching and learning. Educators need to harness the power of technology devices to engage students in learning, enhance teaching, and provide opportunities for personalized learning. The International Society for Technology in Education (ISTE) has developed student standards that provide a framework for

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11

Napolitano, Helena Cristina Assunção Santana. "\"Determinação da estrutura cristalina e molecular de três 3-fenil-2-izoxazolin-5-ona-4-benzilideno substituído\"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/75/75131/tde-05062007-170950/.

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Foram determinadas as estruturas cristalinas de três 3-fenil-2- izoxazolin-5-ona-4-benzilideno substituídas com potencial atividade antiinflamatória, a partir dos dados difratométricos de raios-X, usando os Métodos Diretos. O refinamento foi obtido pelo método dos Mínimos Quadrados. O composto C16H11NO2 cristalizou no sistema cristalino monoclínico, grupo espacial P21/a, a = 11,786(5) Å, b = 5,745(1) Å, c = 17,862(5) Å, ß = 95,988(5)º, Z = 4, V = 1202,8(12) Å3 . O composto C17H13NO3 cristalizou no sistema cristalino ortorrômbico, grupo espacial Pna21, a = 11,652(5) Å, b = 6,000(5) Å, c = 19,54

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12

CHOLLET, MARYLENE. "Contribution a l'etude des effets electroniques des restes 4 ou 5-1,2-dithiole-3-thione-yl et 4 ou 5-1,2-dithiole-3-one-yl." Rennes 1, 1997. http://www.theses.fr/1997REN10079.

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L'etude du sens et de l'intensite des effets electroniques des restes 5-1,2-dithiole-3-thione(one)-yl et 4-1,2-dithiole-3-thione(one)-yl fait l'objet de cette these. Elle a ete realisee en suivant deux voies de recherche. La premiere a consiste a determiner les valeurs de pka, en milieu aqueux par spectrophotometrie u. V. -visible, de plusieurs 4 ou 5-aminophenyldithiolethiones(ones) et de la 4-p-hydroxyphenyldithiolethione. Les resultats obtenus, entres dans des correlations de type hammett, permettent d'affirmer que : - les restes 5-1,2-dithiole-3-thione(one)-yl sont fortement attracteurs pa

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13

Howell, H. E. "Studies on the mechanisms of ovulatory blockade by 3beta-hydroxyandrost-5-en-17-one in the guinea pig." Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356798.

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14

Yuen, Wai-pui. "A comparison of the effects of 5-week traditional circuit training and 5-week plyometric circuit training on the physical fitness of secondary one male students in Hong Kong." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21305195.

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15

Bos, Maxence. "Synthèse de [gamma]-lactones polyfonctionnelles chirales par catalyse énantiosélective." Thesis, Reims, 2015. http://www.theses.fr/2015REIMS017.

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La mise au point de méthodologies de synthèse permettant d’obtenir des substances énantiopures présentant une diversité structurale importante est une préoccupation majeure de la chimie contemporaine. L’efficacité de ces approches doit être désormais évaluée au regard de critères tel que la pureté optique et l’analyse de l’impact écologique des processus mis en jeu. Au cours de ce travail nous avons développé de nouvelles méthodologies permettant d’accéder à des γ-lactones polyfonctionnelles chirales. La 5-hydroxyfuran-2(5H)-one, petite molécule bio-sourcée, a servi d’élément clé pour la const

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16

Yamada, Hisatsugu. "Studies on naphthoquinone-sensitized one-electron photooxidation at 5-methylcytosine in DNA and its application to DNA methylation analysis." 京都大学 (Kyoto University), 2008. http://hdl.handle.net/2433/136304.

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17

Oliver, E. John C. (Edward John Clavering). "Guacamayo's old song and dance : an opera in one act for 5 voices and amplified chamber ensemble." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=76520.

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The notion of identity between the ancient and the contemporary, which has its source in Mayan studies, informs the design principles of this work. Specific techniques are listed for the design of musical space and time in Guacamayo, which is "a musical drama that strives for synthesis." There follows an outline of the principle motivic material, approaches to melodic construction and text setting, techniques used to design space (or pitch) and time (or rhythm)--including traditional harmony, symmetrical modes, non-octaviating space and random number generation in the first case, and speech rh

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18

Ambeu, N'ta Christelle. "Synthèse d'analogues de la pentamidine porteurs de plateformes hétérocycliques (rhodanine, benzimidazole, pyrazole et imidazole) et leurs évaluations biologiques." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1S137/document.

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Ce manuscrit de thèse concerne le développement d'une stratégie de synthèse multi-étapes de nouveaux composés comportant plusieurs plateformes hétérocycliques (rhodanine, benzimidazole, pyrazole et imidazole) à visée thérapeutique multiple contre la malaria, la leishmaniose, le cancer et les maladies neurodégénératives. Les pharmacomodulations de ces composés ont été élaborées sur la base du modèle de la pentamidine 35 comportant 2 motifs benzamidines (parties « Ouest » et « Est »). En effet, la substitution de sa partie « Ouest » par une plateforme rhodanine ou benzimidazole et de sa partie «

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Mark, Noah William. "Batch and Column Transport Studies of Environmental Fate of 3-nitro-1,2,4-triazol-5-one (NTO) in Soils." Thesis, The University of Arizona, 2014. http://hdl.handle.net/10150/321539.

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NTO (3-nitro-1,2,4-triazol-5-one) is one of the new explosive compounds used in insensitive munitions (IM) and developed to replace traditional explosives, TNT and RDX. Data on NTO fate and transport is needed to determine its environmental behavior and potential for groundwater contamination. In this study, we measured how NTO in solution interacts with different types of soils and related soil properties to transport and fate behavior. We conducted a series of kinetic and equilibrium batch soil sorption experiments and saturated column transport studies under steady-state and transient condi

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20

LE, CAMPION LAURENCE. "Degradation microbiologique de l'onta ou 5-nitro-1,2,4-triazole-3-one, et comparaison avec le metabolisme chez les mammiferes." Paris 11, 1997. http://www.theses.fr/1997PA112248.

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Le 5-nitro-2,2,4-triazole-3-one (onta) est un explosif a haute performance et faible sensibilite. Certains processus industriels generent des dechets aqueux contenant l'onta a 15 g/l. Ceci interdit le rejet de ces eaux en l'etat, et necessite la mise au point d'un procede de destruction peu couteux et respectueux de l'environnement. Nous avons entrepris l'etude de la biodegradation de l'onta. Des methodes d'analyse de l'onta et de ses derives ont ete mises au point. L'analyse qualitative et quantitative a ete realisee soit par clhp sur une colonne de graphite poreux, soit par electrophorese ca

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21

Giere, Samuel D. "A new glimpse of Day One : an intertextual history of Genesis 1.1-5 in Hebrew and Greek texts up to 200 CE." Thesis, University of St Andrews, 2007. http://hdl.handle.net/10023/155.

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This thesis is an unconventional history of the interpretation of Day One, Genesis 1.1-5, in Hebrew and Greek texts up to c. 200 CE. Using the concept of ‘intertextuality’ as developed by Kristeva, Derrida, and others, the method for this historical exploration looks at the dynamic interconnectedness of texts. The results reach beyond deliberate exegetical and eisegetical interpretations of Day One to include intertextual, and therefore not necessarily deliberate, connections between texts. The purpose of the study is to gain a glimpse into the textual possibilities available to the ancient re

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Vickers, Richard John. "Diastereoselective additions to iminium ions in the synthesis of enantiopure Î± amino acids : stereocontrol using the (S) 5 phenylmorpholin 2 one template." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269730.

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23

Odelius, Karin. "Design of polyester and porous scaffolds." Licentiate thesis, Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-493.

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Agnus, Benoît. "Photodétection de la 5 β Pregnane 3 α ol 20 one sur une phase alkyle C4 et sur une phase β-cyclodextrine greffée". Paris 12, 1993. http://www.theses.fr/1993PA120065.

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La 5 beta pregnane 3 alpha ol-20 one ou pregnanolone, steroide endogene est issue du metabolisme de la progesterone. Elle ne presente pas de chromophore qui permette sa detection et sa quantification en hplc. L'etude de la photodetection indirecte de la pregnanolone sur deux supports differents, avec la progesterone et la testosterone comme revelateur, permet de detecter 2 nanomoles de preganolone injectees. Le premier support utilise est un gel de silice greffe avec de la beta cyclodextrine, le second rapport est une phase alkyle c4. Dans ce cas, il est necessaire d'ajouter a l'eluant un agen

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HEMONIC, DANIELE. "Etude cinetique et thermodynamique de l'extraction du cuivre par la 1-phenyl-3-methyl-4-stearoyl-pyrazol-5-one : comparaison a d'autres extractants." Paris, ENMP, 1987. http://www.theses.fr/1987ENMP0156.

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Etude de l'extraction du cuivre en milieu sulfate par une pyrazolone diluee dans le solvesso 150. Determination des constantes d'equilibre et de cinetique d'extraction, utilisation d'un modele thermodynamique

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Hemonic, Danielle. "Etude cinétique et thermodynamique de l'extraction du cuivre par la 1-phényl-3-méthyl-4-stéaroyl-pyrazol-5-one comparaison à d'autres extractants /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376059420.

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Srivastava, Rajiv. "Novel methods to synthesize aliphatic polyesters of vivid architectures." Licentiate thesis, KTH, Fibre and Polymer Technology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-511.

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<p>Cross-linked films of ε-caprolactone (CL) and 1,5-dioxepan-2-one (DXO) having various mole fractions of monomers and different cross-link densities were prepared using 2,2’-bis-(-caprolactone-4-yl) propane (BCP) as cross-linking agent and Sn(Oct)2 as catalyst. Reaction parameters were examined to optimize the film-forming conditions. Networks obtained were elastomeric materials, easy to cast and remove from the mould. Effect of CL content and cross-link density on the final properties of the polymer network was evaluated. Thermal, mechanical and surface properties of the films were control

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Gwachha, Kabita. "Solid State Characterization of 3-(5-methoxy, 2-methyl-1H-indol-3-yl)-1-(4-pyridinyl)-2-propen-1-one (MOMIPP) and its solvates." University of Toledo Health Science Campus / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=mco1556641812034105.

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29

Aquino, Estefania da Costa. "Aplicação de 5-bromo-1,1,1-trifluor-4-metoxipent-3-en-2-ona na síntese de pirróis, pirazóis, pirimidinas e 1,2,3-triazóis." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/4275.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>This thesis reports the synthesis of various series of trifluoromethyl substituted nitrogenated heterocycles, such as pyrroles, pyrazoles, pyrimidines and 1,2,3-triazoles, exploiting the synthetic versatility of 5-bromo-1,1,1-trifluoro-4-methoxypent-3-en-2-one in reactions with nitrogenated nucleophiles. In this way, synthesis of a novel series of 4-amino-3-trifluoromethyl-1H-N-substituted pyrroles was performed through two reaction steps. In the first stage is an addition reaction of primary or secondary amine in the 4-position

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30

Yuen, Wai-pui, and 袁偉培. "A comparison of the effects of 5-week traditional circuit training and5-week plyometric circuit training on the physical fitness ofsecondary one male students in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31961447.

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31

Bassoude, Ibtissam. "Synthèse de nouveaux dérivés pyrazolo[1,5-a]pyrimidiniques à visée biologique." Phd thesis, Université d'Orléans, 2012. http://tel.archives-ouvertes.fr/tel-00789954.

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Nos travaux de thèse portent sur la mise au point de nouvelles méthodes de synthèse permettant l'accès de façon rapide et efficace à différents dérivés pyrazolo[1,5-a]pyrimidiniques diversement fonctionnalisés.La première partie de ce travail concerne l'étude et l'application de la condensation de la pyran-2-one avec les 5(3)-amino-3(5)-arylpyrazoles que ce soit par chauffage classique ou sous irradiation micro-onde. Par la suite, un nouveau procédé d'(hétéro)arylation pallado-catalysé direct régiosélectif a été mis à profit pour élaborer des pyrazolo[1,5-a]pyrimidines fonctionnalisées tant en

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Mefetah, Hafid. "Benzo(b)-1,8-naphthyridine-5-one : synthese et activite antiparasitaire de nouveaux derives n-alkyles : synthese et caracterisation de tetracycles derives de la molecule-titre." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX22956.

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Claesson, Hans. "Synthesis and Properties of Branched Semi-Crystalline Thermoset Resins." Doctoral thesis, KTH, Fibre and Polymer Technology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3583.

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<p>This thesis describes the synthesis and characterization ofbranched semi-crystalline polymers. Included in this work isthe SEC characterization of a series of dendrimers. Thebranched semi-crystalline polymers were synthesized in order toinvestigate the concept of their use as powder coatings resins.This concept being that the use of branched semi-crystallinepolymers in a UV-cured powder coating system may offer a lowertemperature alternative thus allowing the use of heat sensitivesubstrates and the added benefit of a reduced viscositycompared to linear polymers.</p><p>A series of branched p

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Becker, Tobias [Verfasser], Wilhelm [Gutachter] Boland, Georg Gutachter] Pohnert, and Wittko [Gutachter] [Francke. "3-Nitropropanoic acid and isoxazolin-5-one derived glucosides in chrysomelina larvae : synthesis, biosynthesis, occurrence and toxicity / Tobias Becker ; Gutachter: Wilhelm Boland, Georg Pohnert, Wittko Francke." Jena : Friedrich-Schiller-Universität Jena, 2017. http://d-nb.info/1177602245/34.

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Misbahi, Houriya. "Synthèse de nouveaux dérivés de la benzo[b]-1,8-naphthyridine-5-one : étude de l'activité de réversion de la résistance aux anticancéreux et à la chloroquine." Aix-Marseille 2, 2003. http://www.theses.fr/2003AIX22952.

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Khatiwada, Raju, and Raju Khatiwada. "Mineral Surface-Mediated Transformation of Insensitive Munition Compounds." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/621565.

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Abiotic transformation of compounds in the natural environment by metal oxides plays a significant a role in contaminant fate and behavior in soil. The ability of birnessite, ferrihydrite and green rust to abiotically transform insensitive munitions compounds (IMCs) parent (2,4 dinitroanisole [DNAN] and 3-nitro-1,2,4-triazol-5-one [NTO]), and daughter products (2-methoxy-5-nitro aniline [MENA], 2,4-diaminoanisole [DAAN]of DNAN; and 5-amino-1, 2, 4-triazol-3-one [ATO] of NTO) was studied in batch reactors under strictly controlled pH and ionic strength. The objectives of the study were to (i) a

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Gelmini, Andrea. "Valorizzazione di molecole da materie prime rinnovabili: la trasformazione del 2,5-diidrossimetilfurano con catalisi acida." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/5727/.

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The present work is part of a larger project aimed at obtaining compounds of industrial interest from renewable sources. The work is particularly aimed to investigate the reactivity of 2,5-bis-hydroxymethylfuran (BHMF), an important building block of organic nature easily obtainable from biomass, with acid catalysis. Through the study of the reactivity of BHMF in water, in the presence of an heterogeneous acid catalyst (Amberlyst 15), has been developed a new synthetic method for the preparation of α-6-hydroxy-6-methyl-4-enyl-2H-pyran-3-one a derivative whose molecular skeleton is similar to t

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Zeinyeh, Waël. "Conception et synthèse d'hétérocycles azotés et de dérivés stéroïdiens, modulateurs potentiels de transporteurs ABC (glycoprotéine-P)." Phd thesis, Université Claude Bernard - Lyon I, 2010. http://tel.archives-ouvertes.fr/tel-00874305.

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La multichimiorésistance est caractérisée par une résistance simultanée à des agents chimiothérapeutiques de structures diverses, induite notamment par l'efflux des substances actives hors des cellules. Les transporteurs ABC (ATP-Binding Cassette) sont des protéines transmembranaires impliquées dans cet efflux et qui participent à l'échec du traitement de certains cancers. Par ailleurs, ce mécanisme d'efflux a également été évoqué dans le cadre de la résistance de certains microorganismes aux antimicrobiens. Dans cette étude, nous avons conçu et synthétisé des dérivés susceptibles d'inhiber ce

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Bihel, Frédéric. "Innovation moléculaire appliquée à la maladie d'Alzheimer : conception, synthèse, et évaluation biologique de nouveaux composés 3-Alkoxy-4-chloro-Isocoumarine et 3,4-Dihidro-5-Bromo-[1-4]Oxazin-2-One." Aix-Marseille 2, 2002. http://www.theses.fr/2002AIX22110.

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Höglund, Anders. "Controllable degradation product migration from biomedical polyester-ethers." Licentiate thesis, KTH, Fibre and Polymer Technology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4366.

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<p>The use of degradable biomedical materials has during the past decades indeed modernized medical science, finding applications in e.g. tissue engineering and drug delivery. The key question is to adapt the material with respect to mechanical properties, surface characteristics and degradation profile to suit the specific application. Degradation products are generally considered non-toxic and they are excreted from the human body. However, large amounts of hydroxy acids may induce a pH decrease and a subsequent inflammatory response at the implantation site.</p><p>In this study, macromolecu

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Knight, Julian Francis. "Folio of original compositions : Three to one; Earth to Air: Nico's piece; Four Frames; The Poles converge; Scenes of Sainte Victoire; Muted landscape; Isle of the Dead; Uncertain calm; 5 miniatures for piano." Thesis, Royal Holloway, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368928.

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Vasconcelos, Stanley Nunes Siqueira. "Síntese de 5-organoteluro-1H-1,2,3-triazóis-1,4-dissubstituídos, funcionalização via reação de acoplamento cruzado de Sonogashira e síntese one-pot de derivados do indol-3-glioxila e indol-3-glioxil-1,2,3-triazóis." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-16012014-141941/.

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No capítulo 1 apresentamos uma síntese eficiente de compostos 5-organoteluro-1H- 1,2,3-triazóis realizada via reação de cicloadição [3+2] entre azidas orgânicas e alquinos substituídos com organotelúrio. Além disso, os 5-organoteluro-1H-1,2,3-triazóis foram funcionalizados na posição 5 do anel triazólico por reação de acoplamento cruzado de Sonogashira. A regioquímica dos produtos de cicloadição foram descritas com base em experimentos de RMN, cálculos teóricos e cristalografia de raio-x. Apresentamos uma proposta mecanística para a cicloadição mediada por cobre, baseada em experimentos de esp

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Finne, Anna. "Novel Possibilities for Advanced Molecular Structure Design for Polymers and Networks." Doctoral thesis, KTH, Polymerteknologi, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3623.

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Synthetic and degradable polymers are an attractive choicein many areas, since it is possible to control the way in whichthey are manufactured; more specifically, pathways tomanipulate the architecture, the mechanical properties and thedegradation times have been identified. In this work,L-lactide, 1,5-dioxepan-2-one and ε-caprolactone were usedas monomers to synthesize polymers with different architecturesby ring-opening polymerization. By using novel initiators,triblock copolymers, functionalized linear macromonomers andstar-shaped aliphatic polyesters with well-defined structureshave been s

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Shepherd, Deborah Pamela. "The promotion of mental health and emotional wellbeing of children (5-13) through participatory partnership work with school communities in one local authority : a realistic evaluation of the 'treasure project', a three-year children's fund project." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/1613/.

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This is an evaluative study of an ecological, multi-faceted, multi-levelled school-based mental health and emotional wellbeing project , called the ‘Treasure Project’. The project team directly supported 3,452 children and trained 607 staff from 56 schools. Realistic Evaluation (Pawson & Tilley, 1997) informed the evaluation. Theories, developed from a review of literature, were used to derive a framework of hypotheses about effective work in the area of mental health and emotional wellbeing. Data collected about the project was checked against the framework leading to new theories and hypothe

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Fernandez, Anne-Marie. "Préparation de γ-butyrolactones γ-alkylées optiquement pures à partir de l'acide L-tartrique. Application à la synthèse totale de la L-bioptérine". Rouen, 1996. http://www.theses.fr/1996ROUES025.

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Une nouvelle méthode pour la préparation de gamma-butyrolactones optiquement pures est proposée. Une stratégie de synthèse donnant accès à deux types de chirons carbonylés (cétones et aldéhyde) a permis le développement de deux réactions hautement stéréosélectives créant ainsi un troisième centre stéréogénique : la réduction des cétones, (2R, 3R)-2,3-dipivaloxy-4-oxo alcanoates de méthyle par le borohydure de sodium dans le méthanol mène aux alcools correspondants (4R), avec des ee>98%, précurseurs des (2R,3S,4R)-2,3-dipivaloxy-4-alkylbutyrolactones. L'addition d'organomagnésiens sur l'aldéhyd

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LAKKIS, ZAHREDDINE ZEINAB. "Aspects thermodynamiques et cinetiques de l'extraction de metaux divalents par des acyl-4-pyrazolones-5." Strasbourg 1, 1986. http://www.theses.fr/1986STR13001.

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Extraction de cd et zn a partir des milieux aqueux, perchlorate, nitrate et sulfate par des melanges de phenyl-1 methyl-3 benzoyl-4 pyrazolone-5 et de sels d'ammonium lipophiles. Le pyrazolonate de nh::(4) est l'agent reel de synergie. Mecanisme de transport de cuivre par des acyl-4 pyrazolones-5 a travers une membrane liquide epaisse

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Gomes, Karina Santos. "Papel dos receptores 5-HT2a e 5-HT2c da matéria cinzenta periaquedutal nas reações de defesa em camundongos: influência da experiência prévia ao teste e do modelo empregado." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/59/59134/tde-30102009-172520/.

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A exposição de roedores ao labirinto em cruz elevado (LCE) aumenta a esquiva aos braços abertos e leva à perda do efeito de fármacos ansiolíticos numa reexposição ao aparelho, um fenômeno conhecido como one-trial tolerance (OTT). Dentre as hipóteses sugeridas para explicar a OTT estão a mudança qualitativa de estado emocional e a habituação da atividade locomotora. O presente estudo investigou os efeitos de exposições sucessivas de camundongos ao LCE sobre os níveis de corticosterona plasmática. Ainda, o estudo empregou injeção sistêmica de diazepam antes do teste e reteste para avaliar se a e

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Cohen, Victoria. "Tracking the early number skills performance of 5- to 7-year-old students : a longitudinal study." Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/3149.

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This longitudinal study tracks how 5- to 7-year-olds perform with early number skills. The aim of this study is to diagnose at-risk mathematics students by distinguishing the skills that, if not mastered by the end of Kindergarten, lead to greater difficulty in mathematics in 1st grade. This study’s methodology is mixed as it follows an exploratory and inductive path in light of its use of a hypothesis, an interpretive path in light of its interest in the individual student, and a positivist path in light of its focus on developing rules from analyzed data. An oral diagnostic test based on a c

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Duman, Isa. "Coke characterization on HZSM-5, Fe/ZSM-5, Ni/ZSM-5, and Fe-Ni/ZSM-5 from Catalytic Fast Pyrolysis of Biomass." Thesis, KTH, Skolan för kemi, bioteknologi och hälsa (CBH), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-226910.

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The combustion of fossil fuels has for a long time been a problem from an environmental and sustainability point of view, especially when it comes to the emissions of atmospheric carbon dioxide. The environmental concern has for instance shifted the attention towards finding new sustainable alternatives for producing chemicals and fuels, as a substitute to today’s dependence on fossil based crude oil. Catalytic Fast Pyrolysis of biomass is an excellent way to produce valuable chemicals and fuels using renewable resources. However, the process has some drawbacks, for example rapid deactivation

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Sahmoune, Amar. "Extractions synergiques de metaux divalents de transition par association d'une acyl-4-pyrazolone-5 avec des polyethers cycliques et acycliques." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13116.

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Extractions de co. Zu. Cd et cu divalents par les melanges phenyl-1 methyl-3 benzoyl-4 pyrazolone-5 ethers crown. La coextraction alcalins-alcalinoterreux complexes par les composes crown et des metaux divalents est possible quand la taille de la cavite de l'ether-crown est voisine de celle de l'alcalin (ou alcalino-terreux) et quand l'ion ml::(3)**(-) est suffisamment stable

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