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Journal articles on the topic '547/.05'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Chaix, Benjamin, Jean-Emmanuel Bibault, Rolland Romain, et al. "Assessing the performances of a chatbot to collect real-life data of patients suffering from primary headache disorders." DIGITAL HEALTH 8 (January 2022): 205520762210977. http://dx.doi.org/10.1177/20552076221097783.

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Background There are many scales for screening the impact of a disease. These scales are generally used to diagnose or assess the type and severity of a disease and are carried out by doctors. The chatbot helps patients suffering from primary headache disorders through personalized text messages. It could be used to collect patient-reported outcomes. Objective The aims of this study were (1) to study whether the collection and analysis of remote scores, without prior medical intervention, are possible by a chatbot, (2) to perform suggested diagnosis and define the type of headaches, and (3) to

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J, RAGHAVENDRA K., and A. SURESH. "An analysis of economic benefits from adoption of drought tolerant soybean (Glycine max) in Madhya Pradesh." Indian Journal of Agricultural Sciences 90, no. 10 (2020): 1888–93. http://dx.doi.org/10.56093/ijas.v90i10.107890.

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The research conducted to estimate the potential economic benefit from adoption of drought tolerant soybean (Glycine max (L.) Merr.) variety NRC-7 in Indore district of Madhya Pradesh, where majority of area is under rainfed system. In this study, the potential economic benefit in terms of economic surplus and risk reduction was estimated for NRC-7 and alternative varieties, JS-93-05 and JS 95-60. NRC-7 requires less cost of cultivation compared to other two varieties, and withstands stress condition. In normal condition, the economic surplus for NRC-7 was ₹ 686 million per year, and that of,

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Debora Valentina, Tience, Firmanto Adi Nurcahyo, and Dewi Puri Astiti. "Self-efficacy and well-being of youth during the COVID-19 pandemic in Indonesia." Salud mental 46, no. 4 (2023): 185–92. http://dx.doi.org/10.17711/sm.0185-3325.2023.023.

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Introduction. The impact of the COVID-19 pandemic on the well-being of young people has attracted the concerned of many parties. Self-efficacy, an individual’s belief to cope with various situations, is believed to have a relationship with individual’s psychological well-being. Objective. To explore the relationship between self-efficacy and well-being of young people in Indonesia during the COVID-19 pandemic. Method. A cross-sectional design with a convenience sample of high schools and universities students in Indonesia. The number of participants were 365 young people aged 15-23 years (M =

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Киселев, В. А., та З. В. Киселева. "Анализ стилей спортивного плавания для коррекции осанки". Тенденции развития науки и образования 97, № 10 (2023): 60–63. http://dx.doi.org/10.18411/trnio-05-2023-547.

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В статье рассматривается современная проблема, связанная с ухудшением осанки детей, которым предписано для коррекции осанки заниматься плаванием. Рассматриваются спортивные стили плавания с позиции корригирующих средств.

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Seyyar, Gulce Kallem, Bahar Aras, and Ozgen Aras. "Trunk Control in Children With Ataxic Cerebral Palsy." Perceptual and Motor Skills 126, no. 5 (2019): 815–27. http://dx.doi.org/10.1177/0031512519858275.

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This study aimed to investigate the clinical characteristics of trunk control in children with ataxic cerebral palsy (CP). We included 15 children with ataxic CP with a mean age of 9.46 years ( SD = 1.08 years, 5–17 years) and 15 healthy children with a mean age of 9.06 years ( SD = 0.84 years, 5–13 years). While the small sample size and large age range used here were not ideal for generalizability, they were made necessary by the rarity of this clinical sample. We used the Gross Motor Function Classification System Expanded and Revised (GMFCS-E&R) to classify the children’s functional le

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Liu, Liangchen, Di Yang, Shuanglin Zhao, Shiliang Ding, and Yuntao Ni. "Clinical Observation of Wound Fluid Extravasation after Shoulder Arthroscopy." Journal of Contemporary Medical Practice 6, no. 6 (2024): 23–27. http://dx.doi.org/10.53469/jcmp.2024.06(06).05.

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Fluid leakage to the outside of the wound after shoulder arthroscopy can present a risk of complications such as wound infection and delayed wound healing. Most relevant studies dealt with fluid leakage to the internal environment and did not focus on fluid leakage outside the body and its effect on the wound. We, therefore, focused on and investigated the significance of wound fluid leakage to the body surface after shoulder arthroscopy. Methods: Observational and analyzed patient data from 15 cases of shoulder arthroscopy were used to calculate the amount of fluid exudation by recording the

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Hatendi, P. R., F. M. Mulenga, S. Sibanda, and P. Ndlovu. "The effect of diet and frequency of watering on the performance of growing cattle given food at maintenance." Animal Science 63, no. 1 (1996): 33–38. http://dx.doi.org/10.1017/s1357729800028253.

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AbstractAn 18-week experiment investigated the effects of type of diet and frequency of watering on the performance of growing cattle given food at maintenance (metabolizable energy (ME) allowance (MJ) = 8·3 + 0·091 M where M = live weight of the animal). Three diets with 20: 80 (low, L), 50:50 (medium, M) and 80: 20 (high, H) roughage to concentrate ratios (10·2, 7·8 and 5·4 MJME per kg dry matter) were used in combination with free access to water for 2·5 h once daily or once every 3rd day. A completely randomized-block design with a 3 (diets) × 2 (watering frequencies) factorial arrangement

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Hecking, Julia, Pasha A. Davoudian, and Samuel T. Wilkinson. "Emerging Therapeutics Based on the Amino Acid Neurotransmitter System: An Update on the Pharmaceutical Pipeline for Mood Disorders." Chronic Stress 5 (January 2021): 247054702110204. http://dx.doi.org/10.1177/24705470211020446.

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Mood disorders represent a pressing public health issue and significant source of disability throughout the world. The classical monoamine hypothesis, while useful in developing improved understanding and clinical treatments, has not fully captured the complex nature underlying mood disorders. Despite these shortcomings, the monoamine hypothesis continues to dominate the conceptual framework when approaching mood disorders. However, recent advances in basic and clinical research have led to a greater appreciation for the role that amino acid neurotransmitters play in the pathophysiology of moo

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Kennedy, Katherine, John R. Bowblis, and Katherine M. Abbott. "ONE-TWO PUNCH OF HIGH WAGES AND EMPOWERING PRACTICES FOR MAINTAINING CARE NETWORKS IN NURSING HOMES." Innovation in Aging 3, Supplement_1 (2019): S559—S560. http://dx.doi.org/10.1093/geroni/igz038.2068.

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Abstract Stabilizing certified nursing assistant (CNA) employment is necessary for maintaining care networks and providing high quality of care for nursing home (NH) residents. This study’s objective was to examine the relationship of high wages and empowerment practices on CNA retention. We used the 2015 Ohio Biennial Survey to construct a facility-level dataset of 547 NHs and estimated multivariable linear regressions. NHs that provided both high wages and high empowerment were associated with a 12.95 percentage-point improvement in the CNA retention rate (SE = 4.53, t-value = 2.86, p = 0.00

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Morgan, Juliette, Martin I. Meltzer, Brian D. Plikaytis, et al. "Excess Mortality, Hospital Stay, and Cost Due to Candidemia: A Case-Control Study Using Data From Population-Based Candidemia Surveillance." Infection Control & Hospital Epidemiology 26, no. 6 (2005): 540–47. http://dx.doi.org/10.1086/502581.

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AbstractObjective:To determine the mortality, hospital stay, and total hospital charges and cost of hospitalization attributable to candidemia by comparing patients with candidemia with control-patients who have otherwise similar illnesses. Prior studies lack broad patient and hospital representation or cost-related information that accurately reflects current medical practices.Design:Our case-control study included case-patients with candidemia and their cost-related data, ascertained from laboratory-based candidemia surveillance conducted among all residents of Connecticut and Baltimore and

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Coogan, John J. "Pathogen Control in Complex Fluids with Water-coupled Excimer Lamps at 282 and 308 nm." Photochemistry and Photobiology 81, no. 6 (2005): 1511. http://dx.doi.org/10.1562/2005-05-27-ra-547.

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Goto, Heita, and James A. King. "High-Intensity Demands of 6-a-Side Small-Sided Games and 11-a-Side Matches in Youth Soccer Players." Pediatric Exercise Science 31, no. 1 (2019): 85–90. http://dx.doi.org/10.1123/pes.2018-0122.

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Purpose: The purposes of the present study were to examine high-intensity running distance during 6-a-side small-sided games (SSGs) and 11-a-side matches (11M) in youth soccer players using speed and metabolic power approaches and the magnitude of difference between the high-intensity running distance calculated with the 2 approaches. Method: A total of 11 outfield players (age = 16.3 [0.6] y) performed SSGs with 3 pitch sizes (small SSG [SSGS], medium SSG, and large SSG [SSGL]) and 11M. A Global Positioning System (15 Hz) was employed to calculate total distance covered, distance covered at a

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Chen, Qiong, Xin-lu Cheng, and Xiang-dong Yang. "Influence of New Interaction Potential on MD Simulation of MgSiO3 Perovskite Thermodynamic Properties." Chinese Journal of Chemical Physics 20, no. 5 (2007): 547–51. http://dx.doi.org/10.1088/1674-0068/20/05/547-551.

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Zhang, Ai-jie, and Guo-zhong He. "Quantum Mechanics Rate Constant for the N+ND Reaction." Chinese Journal of Chemical Physics 24, no. 5 (2011): 547–50. http://dx.doi.org/10.1088/1674-0068/24/05/547-550.

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Tao, Qian, Wei Chen, Yao Yao, Ammar Bin Yousaf, and Yan-xia Chen. "Study on Methanol Oxidation at Pt and PtRu Electrodes by Combiningin situInfrared Spectroscopy and Differential Electrochemical Mass Spectrometry." Chinese Journal of Chemical Physics 27, no. 5 (2014): 541–47. http://dx.doi.org/10.1063/1674-0068/27/05/541-547.

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16

Ueda, Sho, Daisuke Oryoji, Ken Yamamoto, et al. "Identification of Independent Susceptible and Protective HLA Alleles in Japanese Autoimmune Thyroid Disease and Their Epistasis." Journal of Clinical Endocrinology & Metabolism 99, no. 2 (2014): E379—E383. http://dx.doi.org/10.1210/jc.2013-2841.

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Background: Autoimmune thyroid disease (AITD) includes Graves disease (GD) and Hashimoto thyroiditis (HT), which partially share immunological features. Determining the genetic basis that distinguishes GD and HT is a key to understanding the differences between these 2 related diseases. Aim: The aims of this study were to identify HLA antigens that can explain the immunopathological difference between GD and HT and to elucidate epistatic interactions between protective and susceptible HLA alleles, which can delineate the distinct function of HLA in AITD etiology. Design: We genotyped 991 patie

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Boegemann, Martin, Michael Woike, Johanna Gillhaus, and Andres Jan Schrader. "Comparison of different prognostic scores versus physician’s subjective prognosis in patients with advanced/metastatic renal cell carcinoma treated with temsirolimus in regular clinical setting: An analysis of the STAR-TOR registry." Journal of Clinical Oncology 35, no. 6_suppl (2017): 441. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.441.

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441 Background: In treatment of metastatic renal cell carcinoma (mRCC) patients several prognostic scores are used: the MSKCC-, IMDC-, and for pts treated with Temsirolimus (TEMS) the Hudes-score. We assessed prognostic value of these scores in TEMS treated cohort and compared the results with physician’s prognosis. Methods: A German multicenter registry for pts with mRCC (NCT00700258) was established to evaluate the safety and efficacy of TEMS in clinical routine. We retrospectively analyzed the data to compare established prognostic scores with risk assessment by the treating physician and m

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Hauta-alus, Helena H., Liisa Korkalo, Riitta Freese, Carina Ismael, and Marja Mutanen. "Urban and rural dietary patterns are associated with anthropometric and biochemical indicators of nutritional status of adolescent Mozambican girls." Public Health Nutrition 21, no. 6 (2017): 1057–64. http://dx.doi.org/10.1017/s1368980017003676.

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AbstractObjectiveThe objective of the present study was to explore whether dietary patterns (DP) are associated with nutritional status indicators among adolescent Mozambican girls.Design/Setting/SubjectsIn this population-based cross-sectional study we used the FFQ data of 547 girls aged 14–19 years from Central Mozambique to derive dietary patterns by means of principal component analysis. We used two-level linear regression models to examine the associations between the DP and anthropometric and biochemical indicators of nutritional status.ResultsWe identified three DP: ‘Urban bread and fat

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Cakra, Cakra. "PENGARUH BUDAYA KERJA TERHADAP EFEKTIVITAS PELAYANAN PUBLIK KANTOR DESA TIMORENG PANUA KECAMATAN PANCA RIJANG KABUPATEN SIDENRENG RAPPANG." PRAJA: Jurnal Ilmiah Pemerintahan 8, no. 2 (2020): 148–54. http://dx.doi.org/10.51817/prj.v8i2.246.

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Abstract  The purpose of this research is to determinate the effect of work culture on the effectiness of public service in the office village of Timoreng Panua, Panca Rijang district, Sidenreng Rappang Regency. The populations of this research is the whole of Family card as much as 547 of 2 hamlets at Timoreng Panua village. The Collecting of Samples using Random Sampling technique and Yount Formula with 10% Standar error, resulting in a sample as much as 55 55 respondents.The data collecting technique of this research is observation, questionnaire, interview and library research.

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Cakra, Cakra. "PENGARUH BUDAYA KERJA TERHADAP EFEKTIVITAS PELAYANAN PUBLIK KANTOR DESA TIMORENG PANUA KECAMATAN PANCA RIJANG KABUPATEN SIDENRENG RAPPANG." PRAJA: Jurnal Ilmiah Pemerintahan 8, no. 2 (2020): 148–54. http://dx.doi.org/10.55678/prj.v8i2.246.

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Abstract  The purpose of this research is to determinate the effect of work culture on the effectiness of public service in the office village of Timoreng Panua, Panca Rijang district, Sidenreng Rappang Regency. The populations of this research is the whole of Family card as much as 547 of 2 hamlets at Timoreng Panua village. The Collecting of Samples using Random Sampling technique and Yount Formula with 10% Standar error, resulting in a sample as much as 55 55 respondents.The data collecting technique of this research is observation, questionnaire, interview and library research.

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Savitri, Ary I., Nasim Yadegari, Julia Bakker, et al. "Ramadan fasting and newborn's birth weight in pregnant Muslim women in The Netherlands." British Journal of Nutrition 112, no. 9 (2014): 1503–9. http://dx.doi.org/10.1017/s0007114514002219.

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Many Muslim women worldwide are pregnant during Ramadan and adhere to Ramadan fasting during pregnancy. In the present study, we determined whether maternal adherence to Ramadan fasting during pregnancy has an impact on the birth weight of the newborn, and whether the effects differed according to trimester in which Ramadan fasting took place. A prospective cohort study was conducted in 130 pregnant Muslim women who attended antenatal care in Amsterdam and Zaanstad, The Netherlands. Data on adherence to Ramadan fasting during pregnancy and demographics were self-reported by pregnant women, and

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Hewitt, David J., Sheena K. Aurora, David W. Dodick, et al. "Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine." Cephalalgia 31, no. 6 (2011): 712–22. http://dx.doi.org/10.1177/0333102411398399.

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Background: This study evaluated the CGRP receptor antagonist MK-3207 for acute treatment of migraine. Methods: Multicenter, double-blind, randomized, placebo-controlled, parallel-group, two-stage adaptive study with two interim efficacy analyses to facilitate optimal dose selection. Migraine patients were initially randomized to MK-3207 2.5, 5, 10, 20, 50 and 100 mg or placebo to treat a moderate/severe migraine. One or more doses were to be discontinued based on the first interim analysis and a lower or higher dose could be added based on the second interim analysis. The primary endpoint was

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D'ANGELINO, JOSÉ LUIZ, MAURÍCIO GARCIA, and EDUARDO HARRY BIRGEL. "Productive and reproductive performance in cattle infected with bovine leukosis virus." Journal of Dairy Research 65, no. 4 (1998): 693–95. http://dx.doi.org/10.1017/s0022029998003124.

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Economic losses caused by enzootic bovine leukosis (EBL) have been of interest since World War II, when the neoplastic form of EBL increased dramatically in Europe. Olson (1974) and House et al. (1975) showed that animals with lymphosarcoma caused by the bovine leukosis virus (BLV) had reduced milk yields, a less efficient reproductive performance and high veterinary costs and mortality rates, while many carcasses were rejected at slaughter. However, the actual impact of BLV infection in cattle without lymphosarcoma is not clear. The purpose of the study reported here was to compare some produ

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Hernandez, Christina S., Michael C. Monuteaux, Richard G. Bachur, Jeanine E. Hall, and Pradip P. Chaudhari. "Trends in ED Resource Use for Infants 0 to 60 Days Evaluated for Serious Bacterial Infection." Hospital Pediatrics 11, no. 12 (2021): 1377–85. http://dx.doi.org/10.1542/hpeds.2021-005966.

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OBJECTIVES We examined trends in resource use for infants undergoing emergency department evaluation for serious bacterial infection, including lumbar puncture (LP), antibiotic administration, hospitalization, and procalcitonin testing, as well as the association between procalcitonin testing and LP, administration of parenteral antibiotics, and hospitalization. METHODS We performed a cross-sectional study of infants aged 0 to 60 days who underwent emergency department evaluation for serious bacterial infection with blood and urine cultures from 2010 to 2019 in 27 hospitals in the Pediatric He

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Bhattacharya, A. N., S. Al-Mutairi, A. Hashimi, and S. Economides. "Energy and protein utilization of lucerne hay and barley grain by yearling camel calves." Animal Science 47, no. 3 (1988): 481–85. http://dx.doi.org/10.1017/s0003356100003639.

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ABSTRACTTwo trials were conducted with eight yearling camels with an average intial body weight of 300 kg, to evaluate protein and energy values of lucerne hay and barley grains. In each trial, eight animals were randomly allotted to two different dietary treatments of coarsely ground lucerne hay or lucerne hay + barley grain (50:50) in such a way that two animals in each of the two blocks received the same ration. Each trial consisted of a 10-day preliminary period followed by a 7-day collection period during which total urine and faeces collections were made, and samples were processed and c

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Johnston, E. A., K. S. Petersen, and P. M. Kris-Etherton. "Daily intake of non-fried potato does not affect markers of glycaemia and is associated with better diet quality compared with refined grains: a randomised, crossover study in healthy adults." British Journal of Nutrition 123, no. 9 (2020): 1032–42. http://dx.doi.org/10.1017/s0007114520000252.

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AbstractEpidemiological studies suggest that consumption of potatoes is associated with increased risk of cardiometabolic diseases. However, few clinical trials have empirically tested this. The aim of this single-blind, randomised, crossover study was to evaluate the effect of daily potato consumption, compared with refined grains, on risk factors for cardiometabolic diseases. It was hypothesised that no difference in cardiometabolic endpoints would be detected between conditions, but diet quality would improve with potato consumption. Healthy participants on self-selected diets received one

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Fonseca, A. J. M., A. A. Dias-da-Silva, and A. L. G. Lourenço. "Effects of maize and citrus-pulp supplementation of urea-treated wheat straw on intake and productivity in female lambs." Animal Science 73, no. 1 (2001): 123–36. http://dx.doi.org/10.1017/s1357729800058124.

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AbstractTwo experiments with lambs given food indoors and individually penned were designed to study the effects of different levels of ground maize and citrus pulp as supplements of a diet based on urea-treated straw (5 kg urea per 100 kg straw) offered ad libitum over a period of 16 weeks (experiment 1) or 10 weeks (experiment 2). The voluntary intake, live-weight gain (LWG), organic matter digestibility (OMD), urinary allantoin-nitrogen (UAN) excretion and acetate clearance rate were measured. The lambs were blocked on weight and randomly assigned to the treatments described below. Ruminal

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Alexander, S. L., C. H. G. Irvine, J. H. Livesey та R. A. Donald. "Effect of isolation stress on concentrations of arginine vasopressin, α-melanocyte-stimulating hormone and ACTH in the pituitary venous effluent of the normal horse". Journal of Endocrinology 116, № 3 (1988): 325–34. http://dx.doi.org/10.1677/joe.0.1160325.

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ABSTRACT A non-surgical, non-stressful technique was used for collection of pituitary venous blood from five conscious horses every minute for two 10-min periods before and during isolation from the herd, which caused a predictable, yet humane and physiological, emotional stress. Pituitary blood was also sampled every 5 min for two approximately 90-min periods before and after isolation, while jugular blood was sampled every 15 min throughout the experiment. During isolation, all horses became agitated, hyperventilating and sweating. Packed red cell volume increased, as did pituitary venous co

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Krzakowski, M., J. Douillard, R. Ramlau, et al. "Phase III study of vinflunine versus docetaxel in patients (pts) with advanced non-small cell lung cancer (NSCLC) previously treated with a platinum-containing regimen." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7511. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7511.

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7511 Background: Vinflunine (VFL) is a new microtubule inhibitor of the vinca alkaloid class with clinical activity in NSCLC (J. Bennouna, BJC, 2006). Single-agent efficacy and safety of VFL and docetaxel (DTX) were compared in the 2nd line chemotherapy. Methods: Open-label, multi-center, randomised, phase III study in platinum pre-treated locally advanced/metastatic NSCLC pts. At least 275 pts were to be randomized by arm to receive VFL (320 mg/m2, 20-min IV infusion) or DTX (75 mg/m2, 1-hour IV infusion with dexamethasone over 3 days) every 3 weeks. The primary endpoint was progression free

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Shingfield, K. J., and N. W. Offer. "Evaluation of the spot urine sampling technique to assess urinary purine derivative excretion in lactating dairy cows." Animal Science 66, no. 3 (1998): 557–68. http://dx.doi.org/10.1017/s1357729800009139.

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AbstractThe potential of the spot urine sampling technique as an alternative to performing a total urine collection was evaluated. Twelve multiparous Holstein-Friesian cows were given two experimental diets in a complete change-over design using two 14-day experimental periods. Experimental diets were either silage offeredad libitumwith 7 kg fresh weight concentrate supplement as a single meal (SF), or a complete diet formulated from the same ingredients with a similar foragexoncentrate ratio (CD). Total urine collections were performed every 2 h on days 11 and 14 of each experimental period.

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N., C. Hiragond. "Avifauna diversity of Sadashiv Nagar: Belgaum city, Karnataka, India." Biolife 3, no. 3 (2022): 763–68. https://doi.org/10.5281/zenodo.7297971.

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<strong>ABSTRACT</strong> This paper deals with an assessment of avifauna diversity and their migratory status in Sadashiv nagar of Belagavi city in North Karnataka, India. A weekly observation from September 2011 to August 2013 for the period of 2 years resulted in documentation of 75 bird species belongs to 16 orders, 39 families and 65 genera. Passeriformes alone represent 59% of the total bird species recorded followed by Ciconiformes (5%) and Columbiformes (5%). Among the families Cistcolidae and Motacillidae consists maximum (5 species each) number of bird species followed by Ardeidae, C

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Delgado, Estefan. "EVENTO CEREBROVASCULAR ISQUÉMICO ATEROTROMBÓTICO: ESTUDIO DE CASO." Universidad Ciencia y Tecnología 24, no. 103 (2020): 28–34. http://dx.doi.org/10.47460/uct.v24i103.354.

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Los eventos cerebrovasculares componen una de las principales causas de defunción en el Ecuador, pese a que la prevención de estas condiciones son conocidas, los factores de riesgos prexistentes coadyuvan a su aparición, conocido como un gran desencadenante de discapacidad, éstos eventos conllevan a padecer trastornos de lenguaje, habla, deglución y voz. La fonoaudiología es la rama de la salud que se dedica a tratar estos trastornos. En la presente investigación se expone un caso, sus manifestaciones y valoraciones clínicas. El caso corresponde a una persona de sexo femenino de 85 años de eda

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Montard, R., B. Clement, C. Putz, M. Barrali, B. Delbosc, and M. Montard. "547 Manifestations ophtalmologiques de la maladie de Lyme." Journal Français d'Ophtalmologie 28 (March 2005): 300. http://dx.doi.org/10.1016/s0181-5512(05)73667-6.

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Mamounas, Eleftherios, Hanna Bandos, Priya Rastogi, et al. "Abstract PD15-05: Assessment of estrogen receptor (ESR1) mRNA expression for prediction of extended aromatase inhibitor benefit in HR-positive breast cancer using NRG Oncology/NSABP B-42." Cancer Research 82, no. 4_Supplement (2022): PD15–05—PD15–05. http://dx.doi.org/10.1158/1538-7445.sabcs21-pd15-05.

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Abstract Background: In NSABP B-14, the quantitative levels of ESR1 mRNA, assessed using the standardized 21-gene assay and qRT-PCR platform predicted tamoxifen benefit (interaction p-value &lt;0.001). NSABP B-42 evaluated the effect of extended letrozole in postmenopausal women with hormone receptor-positive breast cancer who have completed 5 years of hormonal therapy with either an aromatase inhibitor or tamoxifen followed by an aromatase inhibitor. We proposed to determine if ESR1 mRNA, reported as the quantitative ER single gene score, is predictive of the magnitude of benefit from ext

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Papadakis, Emmanouil, Valia Papageorgiou, Konstantinos Tsepanis, et al. "Impact of Inherited Thrombophilia Factors On Thrombotic Risk in Patients with Newly Diagnosed BCR- Abl (-) Myeloproliferative Disorders; Finally a Role of MTHFR- C677T Polymorphism?" Blood 120, no. 21 (2012): 5065. http://dx.doi.org/10.1182/blood.v120.21.5065.5065.

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Abstract Abstract 5065 Introduction: Myeloproliferative Neoplasms (MPN) are commonly associated with thrombotic complications, which constitute the major cause for morbidity and mortality in these patients. While the pathogenesis of Thrombosis is not yet fully elucidated, the impact of inherited thrombophilia on MPN patients is unknown. MTHFR-C677T polymorphism is a usual variation of the MTHFR gene and exerts weak, if any, prothrombotic role mainly through increased homocysteine levels. Up to date there are no specific guidelines for treatment of thrombotic events in MPN patients. Objectives:

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Thomas, Deborah A., Stefan Faderl, Jorge Cortes, et al. "Update of the Hyper-CVAD and Imatinib Mesylate Regimen in Philadelphia (Ph) Positive Acute Lymphocytic Leukemia (ALL)." Blood 104, no. 11 (2004): 2738. http://dx.doi.org/10.1182/blood.v104.11.2738.2738.

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Abstract The intensive combination chemotherapy program hyper-CVAD in newly diagnosed Ph+ ALL yields complete remission (CR) rates of 90%, but remissions are brief with median CR duration of 16 months [Kantarjian et al, JCO 18:547, 2000]. The activity of the tyrosine kinase inhibitor imatinib given as a single agent in relapsed or refractory Ph+ ALL or chronic myelogenous leukemia in lymphoid blast phase was 20% [Druker et al, NEJM 344:1084, 2001]. A phase II trial of imatinib and hyper-CVAD was conducted in newly diagnosed Ph+ ALL. Imatinib was given 400 mg days 1–14 of each course of therapy

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Amiri-Kordestani, Laleh, Xin Gao, Shrujal Baxi, et al. "Abstract P2-11-05: Generating real-world external comparators for randomized clinical trials (RCTs) in metastatic breast cancer (mBC) using electronic health records (EHRs)." Cancer Research 82, no. 4_Supplement (2022): P2–11–05—P2–11–05. http://dx.doi.org/10.1158/1538-7445.sabcs21-p2-11-05.

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Abstract Objectives: Real-world data (RWD) from the routine care of patients with cancer captured through EHRs is a valuable resource for research. Understanding the relationship between characteristics and outcomes of patients treated in the real world and those treated in clinical trials is essential to produce evaluable trial-like populations using RWD in oncology for research and regulatory purposes. Methods: This study used: a) RWD from the Flatiron Health EHR-derived, de-identified, longitudinal database (comprising patient-level structured and unstructured data, curated via technology-e

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Debus, J. "P-547 Epoetin alfa and survival in patients with non-resectable NSCLC-Interimresults." Lung Cancer 49 (July 2005): S261. http://dx.doi.org/10.1016/s0169-5002(05)81040-2.

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Cipriano, Jailson Araujo, and Lívia da Conceição Costa Zaqueu. "A dupla excepcionalidade altas habilidades/superdotação associada ao transtorno do espectro autista: compreendendo as especificidades." Conjecturas 22, no. 1 (2022): 1023–41. http://dx.doi.org/10.53660/conj-547-802.

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RESUMO Este artigo científico teve como objetivo produzir um Estado da Arte sobre a temática da Dupla Excepcionalidade (D.E) em pessoas com altas habilidades com transtorno do espectro autista nível 1. Trata-se de uma pesquisa bibliográfica, qualitativa e de cunho exploratório. Foi utilizada a técnica de análise de conteúdo de Bardin (2011) para a análise de dados. À luz dos autores até aqui estudados podemos verificar que dos 09 (nove) artigos, 05 (cinco) deles são de revisão e 04 (quatro) são de pesquisa aplicada, o que coaduna com a literatura que aponta a necessidade de mais pesquisa

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Vachiramon, Vasanop, Kanchana Leerunyakul, Chaninan Kositkuljorn, Pamela Chayavichitsilp, and Daniel Romanowitz. "Combined Thiamidol and Low-fluence Q-switched Nd:YAG Laser for the Treatment of Facial Hyperpigmentation." SKIN The Journal of Cutaneous Medicine 9, no. 2 (2025): s547. https://doi.org/10.25251/skin.10.supp.547.

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Background: Thiamidol (isobutylamido thiazolyl resorcinol) is a novel human tyrosinase inhibitor recently shown to be effective in the treatment of hyperpigmentation. Low-fluence Q-switched Nd:YAG 1064-nm laser (LFQS) has proven to be effective for various hyperpigmentary conditions. However, there have been no studies to date on the efficacy and safety of combined Thiamidol and LFQS treatment. Objectives: To compare the efficacy and safety of combined Thiamidol-based serum and LFQS with LFQS monotherapy for facial hyperpigmentation. Materials and Methods: Patients with symmetrical facial hype

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Thomas, Deborah A., Susan O'Brien, Michael Rytting, et al. "Incidence of Central Nervous System (CNS) Relapse in De Novo Adult Acute Lymphoblastic Leukemia (ALL)." Blood 124, no. 21 (2014): 940. http://dx.doi.org/10.1182/blood.v124.21.940.940.

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Abstract In the era of improved outcomes with systemic chemotherapy for de novo adult ALL, prevention of CNS relapse becomes even more paramount. Isolated CNS relapse may herald eventual marrow relapse in the absence of definitive CNS-directed and systemic chemotherapy strategies. CNS prophylaxis can be successfully achieved with intrathecal chemotherapy treatments (IT) in conjunction with systemic chemotherapy inclusive of high-dose methotrexate (MTX) and/or high-dose cytarabine (ara-C) without use of radiation therapy (XRT). The hyper-CVAD regimen (cycles of fractionated cyclophosphamide, vi

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Singh, Manjula, Sanjay Mehendale, Randeep Guleria, et al. "PreVenTB trial: protocol for evaluation of efficacy and safety of two vaccines VPM1002 and Immuvac (Mw) in preventing tuberculosis (TB) in healthy household contacts of newly diagnosed sputum smear-positive pulmonary TB patients: phase III, randomised, double-blind, three-arm placebo-controlled trial." BMJ Open 14, no. 8 (2024): e082916. https://doi.org/10.1136/bmjopen-2023-082916.

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IntroductionTuberculosis (TB) continues to be one of the deadliest infectious diseases over the centuries, killing more people worldwide than any other single infectious disease. There is an urgent need for additional strategies which can expedite efforts to combat TB including a preventive vaccine. In this endeavour, we have developed a protocol for a multisite, double-blind, placebo-controlled clinical trial in India that aims to evaluate the efficacy and safety of two TB vaccines; namely, VPM1002 and Immuvac (M.w) (Mycobacterium Indicus Pranii) (MIP) among healthy household contacts (HHCs)

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Thomas, Deborah A., Hagop M. Kantarjian, Jeffrey L. Jorgensen, et al. "Outcomes Continue to Be Favorable for De Novo Philadelphia Chromosome Negative B-Lymphoblastic Leukemia (ALL) After Therapy with Hyper-CVAD (with or without Rituximab) Regimen." Blood 120, no. 21 (2012): 3572. http://dx.doi.org/10.1182/blood.v120.21.3572.3572.

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Abstract Abstract 3572 The hyper-CVAD regimen [Kantarjian, JCO 18: 547, 2000; Kantarjian, Cancer 101: 2788, 2004] includes intensive cycles of hyper-CVAD (fractionated cyclophosphamide, vincristine [VCR], doxorubicin, dexamethasone) alternating with high dose methotrexate (MTX) and cytarabine every 21 days for 8 courses, followed by maintenance therapy with POMP (6-mercaptopurine, MTX, VCR, prednisone) interrupted by early and late intensifications. The regimen was modified in 1999 to include use of laminar air flow rooms during the induction phase for patients (pts) aged 60 years or older. Th

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Farinha Rodrigues, Célia Regina, and Samara Jamile Mendes. "Implicações do financiamento do tratamento oncológico no SUS e a sua judicialização." JMPHC | Journal of Management & Primary Health Care | ISSN 2179-6750 14, spec (2022): e014. http://dx.doi.org/10.14295/jmphc.v14.1220.

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No contexto recente, o financiamento do Sistema Único de Saúde – SUS tem gerado inúmeros debates acerca de sua tendência de tornar-se cada vez mais insuficiente, sendo considerado por muitos como subfinanciamento ou desfinanciamento, o que poderá acarretar em um aniquilamento da manutenção de um sistema universal de saúde. Esse processo de desfinanciamento tem como principal símbolo a Emenda Constitucional – EC n. 95/2016, que limita a expansão dos gastos públicos pelos próximos 20 anos, baseada no valor das despesas de 2017. Pesquisa publicada em 2016 estimou uma diminuição do recurso em cerc

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MARTINELI, Telma Adriana Pacifico, Carolina De Moura VASCONCELOS, and Eliane Maria de ALMEIDA. "CONCEPÇÃO PEDAGÓGICA E CURRICULAR PARA O ESPORTE NA BASE NACIONAL COMUM CURRICULAR." Trama 14, no. 33 (2018): 106–17. http://dx.doi.org/10.48075/rt.v14i33.19528.

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O estudo teve objetivo analisar a BNCC para o Ensino Fundamental, em seus aspectos pedagógicos e curriculares, com foco na Educação Física e na concepção e classificação do esporte. Tratou-se de um estudo bibliográfico e documental fundamentado em uma perspectiva histórica- crítica. No documento, a Educação Física é um componente curricular que permite a aprendizagem de práticas corporais: brincadeiras e jogos, ginásticas, dança, lutas, práticas corporais de aventura e esportes. Essa concepção fundamenta-se na Praxiologia Motriz, que estuda a lógica interna e externa dos jogos e esportes, a pa

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SUASSUNA, Lívia, and Sabrina Leite FELIX. "SABERES EM MOVIMENTO NO ESTÁGIO DE REGÊNCIA DE TURMA: O ENSINO DE ANÁLISE LINGUÍSTICA POR GRADUANDOS DE LETRAS." Trama 17, no. 41 (2021): 09–27. http://dx.doi.org/10.48075/rt.v17i41.26732.

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Neste estudo pretendemos analisar o modo como alunos da licenciatura em Letras-Português da Universidade Federal de Pernambuco, durante o estágio curricular, atuam para ensinar seus alunos a refletir sobre a língua, concretizando um dos eixos de ensino desse componente curricular que é a análise linguística. A pesquisa, do tipo qualitativo-descritiva, teve como corpus projetos e relatórios de estágio, além de depoimentos dos estagiários, captados no seminário de encerramento das atividades de regência de turma do ensino fundamental. Para montar o referencial teórico, buscamos autores que trata

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Thomas, Deborah A., Hagop M. Kantarjian, Jeffrey L. Jorgensen, et al. "Outcomes for Adult Lymphoblastic Leukemia (ALL) Are Mainly Influenced by Age and Status of Minimal Residual Disease (MRD) by Multiparameter Flow Cytometry (MFC) After Therapy with the Modified Hyper-CVAD (with or without Rituximab) Regimen." Blood 118, no. 21 (2011): 1524. http://dx.doi.org/10.1182/blood.v118.21.1524.1524.

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Abstract Abstract 1524 The hyper-CVAD regimen is an effective frontline program for de novo adult ALL [Kantarjian, JCO 18: 547, 2000; Kantarjian, Cancer 101: 2788, 2004]. Intensive cycles of hyper-CVAD (fractionated cyclophosphamide, vincristine [VCR], doxorubicin, dexamethasone) alternate with high dose methotrexate (MTX) and cytarabine every 21 days for 8 courses, followed by maintenance therapy with POMP (6-mercaptopurine, MTX, VCR, prednisone) interrupted by early and late intensifications. The regimen was modified in 1999 to include use of laminar air flow rooms during the induction phase

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Kuzmin, Sergey V., and Natalia Yu Samodurova. "Hygienic assessment of occupational conditions and schedule of railway employees." Hygiene and sanitation 103, no. 6 (2024): 541–47. http://dx.doi.org/10.47470/0016-9900-2024-103-6-541-547.

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Introduction. Railway transport is one of the leading branches of the national economy, though more than 50% of the railway employees have to undergo some occupational hazards [1]. In recent years, with the introduction of new technologies, significant changes have occurred in the rolling stock. Up to date research on the hygienic assessment of occupational conditions and schedule of railway employees is needed. The purpose of the study is to investigate the occupational conditions and schedule of railway employees, and to identify the principal occupational hazards. Materials and methods. The

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Nja, Cecilia Obi, Kimson Joseph Idiege, Uduak Edet Uwe, et al. "Adoption of artificial intelligence in science teaching: From the vantage point of the African science teachers." Smart Learning Environments 10, no. 1 (2023). http://dx.doi.org/10.1186/s40561-023-00261-x.

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AbstractThis study investigated the factors influencing science teachers' 'Artificial Intelligence' (AI) utilization by using the 'Technology Acceptance Model' (TAM). The factors investigated alongside TAM variables were teachers' data like; age, sex, and residence type. TAM items that were correlated in this study included; self-esteem, stress and anxiousness, ease of utilization, behavioural intention, attitude towards AI usage, and expected benefits. The population of this study comprised all science teachers (170) in the Calabar Education Zone of Cross River State, Nigeria. The sample was

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Sun, Guang-Yi, Hao Jing, Shu-Lian Wang, et al. "Trastuzumab Provides a Comparable Prognosis in Patients With HER2-Positive Breast Cancer to Those With HER2-Negative Breast Cancer: Post Hoc Analyses of a Randomized Controlled Trial of Post-Mastectomy Hypofractionated Radiotherapy." Frontiers in Oncology 10 (January 26, 2021). http://dx.doi.org/10.3389/fonc.2020.605750.

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Background and PurposeWe investigated the locoregional effect of trastuzumab, and determined whether patients with human epidermal growth factor receptor (HER)2-positive breast cancer (BC) treated with trastuzumab could achieve comparable efficacy to that of patients with HER2-negative BC.Materials and MethodsThis was post hoc analyses of data of 793 BC patients from a randomized controlled trial comparing post-mastectomy hypofractionated radiotherapy with conventional fractionated radiotherapy. Survival rates were analyzed by the Kaplan–Meier method and compared by the log-rank test.ResultsPa

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