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1

Castro, Selma Barros Daltro de, José Wellington Marinho Aragão, Solange Mary Moreira Santos, and Ivonete Barreto de Amorim. "O CONTEXTO DO CME EM FEIRA DE SANTANA: REVELANDO AS INTERSEÇÕES ENTRE O CENÁRIO NACIONAL E LOCAL." Interfaces Científicas - Educação 7, no. 3 (2019): 9–26. http://dx.doi.org/10.17564/2316-3828.2019v7n3p9-26.

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A origem dos CME no Brasil tem relação direta com acontecimentos políticos e sociais de caráter mundial, nacional e local, o que exige considerar as relações existentes entre contexto nacional e local. O presente artigo problematizou a criação do Conselho Municipal de Educação, apresentando as relações existentes entre os contextos nacional e local. Para tanto, objetivou 1) contextualizar o surgimento do CME no contexto brasileiro, 2)analisar a criação do Conselho Municipal de Educação de Feira de Santana até o ano de 1996, apresentando as relações políticas estabelecidas no contexto nacional
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2

Zoughbie, Daniel E., Tin Lok James Ng, Jacqueline Y. Thompson, Kathleen T. Watson, Rami Farraj, and Eric L. Ding. "Ramadan fasting and weight change trajectories: Time-varying association of weight during and after Ramadan in low-income and refugee populations." PLOS Global Public Health 2, no. 10 (2022): e0000371. http://dx.doi.org/10.1371/journal.pgph.0000371.

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Obesity is a significant driver of the global burden of non-communicable diseases. Fasting is one approach that has been shown to improve health outcomes. However, the effects of Ramadan fasting differ in that the type, frequency, quantity, and time of food consumption vary. This phenomenon requires in-depth evaluation considering that 90% of Muslims (~2 billion people) fast during Ramadan. To address this issue, we evaluated the pattern of weight change during and following Ramadan for a total of 52 weeks. The study was conducted in Amman, Jordan. Between 2012 and 2015, 913 participants were
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3

Joshi, Y. N., and M. Mazzoni. "3d-Shell excitation in photoabsorption of atomic selenium." Canadian Journal of Physics 66, no. 4 (1988): 326–29. http://dx.doi.org/10.1139/p88-051.

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The photoabsorption spectrum of the inner 3d-shell excitation of atomic selenium was observed in the 500–170 Å region using the flash-pyrolysis technique. The observations, aided by the Hartree–Fock ab initio calculations and least squares fitted parametric calculations, have lead to the classification of 15 lines in the 4p4–3d94s24p5 transition array and 26 lines in the 4p4–3d94s24p4np transitions. Two series ionization limits have been calculated as 517 500 cm−1 (64.15 eV) and 530 000 cm−1 (67.70 eV).
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4

Boadi, Dinah, and M. A. Price. "The effects of pre- and early post-calving management on reproductive performance of beef cows." Canadian Journal of Animal Science 76, no. 3 (1996): 337–42. http://dx.doi.org/10.4141/cjas96-050.

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One hundred and thirty-four pregnant beef cows (liveweight = 544.3 kg ± 73 3 kg SD; condition score = 3.5 ± 0.3 SD), were randomly assigned in January to five management treatments (combinations of feed restriction and weaning time) to study the effects on calving and rebreeding performance. Twenty-seven were feed-restricted (54.7 MJ DE d−1) for the last 3 mo of pregnancy then realimented (3REST); their calves were weaned in October. Thirty were feed-restricted for the last 3 mo of pregnancy (54.7 MJ DE d−1) and the first 2 mo of lactation (99.6 MJ DE d−1), then their calves were weaned and tu
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5

Haneen Farhan Abbas and Sareaa Maseer Gatya Al-Mayahie. "High Prevalence of Coagulase Negative Staphylococci Among Outpatient Women with Acute Urinary Tract Infection." Journal of Wasit for Science and Medicine 18, no. 2 (2025): 20–29. https://doi.org/10.31185/jwsm.542.

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Urinary tract infections (UTIs) caused by coagulase-negative staphylococci (CoNS) represent a major public health challenge worldwide. The current research focused on the isolation and identification of CoNS' species from pregnant and nonpregnant outpatient women with acute UTI and measuring their antibiogram. From a total number of 137 positive cultures, a 111 (81.0 %) were identified as Staphylococcus spp., a 70.2 % of them were CoNS. Eight species of CoNS were detected by two multiplex PCR protocols. Staphylococcus epidermidis was the most prevalent (36/137: 26.2 %), followed by S. haemolyt
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6

Dev, Alka, Willi Horner-Johnson, Andrew Schaefer, et al. "Identifying Pregnant Women With Disabilities and Maternal and Newborn Outcomes." JAMA Network Open 8, no. 3 (2025): e252159. https://doi.org/10.1001/jamanetworkopen.2025.2159.

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ImportancePregnant women with disabilities are at higher risk of poor pregnancy and birth outcomes. Different methods for identifying disability may affect estimates of health disparities in this population.ObjectiveTo compare pregnancy and birth outcomes among pregnant women using different ways of identifying maternal disability.Design, Setting, and ParticipantsRetrospective cohort study of linked vital records and maternal and newborn claims for Medicaid-insured live births from January 2010 to December 2014 in Texas. Data analysis was conducted from October 2023 to May 2024.ExposureBirths
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7

Loh, Ee Wen, and Florence Hui Sieng Tan. "REMISSION OF SURGICAL HYPOPARATHYROIDISM POST ADRENALECTOMY FOR CUSHING'S SYNDROME." Journal of the ASEAN Federation of Endocrine Societies 37, no. 2 (2022): 23. https://doi.org/10.15605/jafes.037.afes.26.

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BACKGROUNDAdrenal insufficiency (AI) is a well-recognized cause of hypercalcemia. In patients with hypoparathyroidism, the effect of coexisting AI on calcium level has not been well- described. CASEWe report a case of a patient with hypoparathyroidism who was able to discontinue her long-term calcium and calcitriol replacement after adrenalectomy for Cushing’s syndrome. A 63-year-old female with post-operative hypopara- thyroidism after total thyroidectomy for papillary thyroid carcinoma (in 2005) was maintained on a stable dose of calcium carbonate 1 g BID and calcitriol 0.5 mcg BID. In 2015,
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8

CUTCLIFFE, J. A. "EFFECTS OF LIME AND GYPSUM ON YIELDS AND NUTRITION OF TWO CULTIVARS OF BRUSSELS SPROUTS." Canadian Journal of Soil Science 68, no. 3 (1988): 611–15. http://dx.doi.org/10.4141/cjss88-059.

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Field experiments were carried out at different locations in Prince Edward Island each year for 3 consecutive years to determine the effects of calcific limestone, dolomitic limestone, and gypsum on yields and nutrition of two cultivars of Brussels sprouts (Brassica oleracea var. gemmifera). The soils at the sites selected had initial pH levels of 4.9–5.7. Preplant, broadcast applications of gypsum at 5.5 t ha−1 resulted in yield increases of about 30% at all locations. Analysis of leaf tissue collected when the sprouts began to form indicated that Ca, Mg, Mn and Zn concentrations of approxima
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9

Vladimirov, Vladimir, Antonina Mostyakova, Leonid Egorov, and Filus Agiev. "POTATO PRODUCTIVITY DEPENDING ON THE METHOD OF APPLICATION OF GROWTH REGULATOR AND CALCULATED BACKGROUND OF MINERAL NUTRITION ON THE GRAY FOREST STEPPE SOIL OF MIDDLE VOLGA REGION." Vestnik of Kazan State Agrarian University 14, no. 4 (2020): 21–26. http://dx.doi.org/10.12737/2073-0462-2020-21-26.

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The reaction of the early ripening potato of Vineta variety to different methods of using growth regulators against the calculated background of mineral nutrition on the gray forest-steppe soil of middle Volga was studied. The effectiveness of processing planting tubers and foliar treatment of plants during their vegetation has been established. The experiments were carried out on the control without the introduction of NPK and on a fertilized background, designed to obtain a tuber crop of 40 tons per hectare. The studies were conducted on gray forest medium loam granulometric composition soil
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10

Santos, Elsom José Gomes, Alessandra Sampaio Couto Santos, Wesdney dos Santos Melo, et al. "Uso do smartphone como instrumento de medida das variáveis termofísicas das salas de aula do Iema-Itaqui Bacanga." Brazilian Journal of Health Review 8, no. 2 (2025): e78798. https://doi.org/10.34119/bjhrv8n2-235.

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Diversos estudos comprovam que quando o ambiente escolar é confortável, ou seja, quando garante a espontaneidade das atividades executadas, a produtividade dos alunos e professores tende a elevar-se consideravelmente. Para avaliar esta situação, esse trabalho tem como objetivo analisar as variáveis termofísicas nas salas de aulas da 1º série do Instituto Estadual de Educação, Ciência e Tecnologia do Maranhão Unidade Itaqui Bacanga (IEMA-Itaqui Bacanga) a nível de conforto térmico por intensidade luminosa, temperatura e umidade relativa do ar. Temos como propósito justificar que o uso do celula
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11

Christian Louis, Kouakou Ehaulier Soh, Same Bebey Francine, Sougué Charles, et al. "Apport de la Rééducation dans la Prise en Charge de la Lombalgie/Lomboradiculalgie Commune Chronique à Abidjan : Amélioration de la Douleur et de la Capacité Fonctionnelle dans 95% des Cas." European Scientific Journal, ESJ 19, no. 27 (2023): 97. http://dx.doi.org/10.19044/esj.2023.v19n27p97.

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Objectif : Evaluer l’apport de la rééducation dans la prise en charge de la lombalgie/lomboradiculalgie commune chronique (LRCC). Patients et méthodes : Il s’est agi d’une étude prospective transversale allant du 1er janvier 2015 au 1er mai 2016 (16 mois), portant sur des cas de LRCC vu en rééducation au CHU de Cocody à Abidjan en Côte d’ivoire. L’échelle Eifel a permis d’évaluer la capacité fonctionnelle des patients. Il s’agissait de comparer l’intensité de la douleur et de son retentissement fonctionnel avant et après rééducation. Résultats : Sur 1380 patients vus, 86 souffraient de LRCC (6
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12

Brinkworth, Grant D., Thomas P. Wycherley, Pennie J. Taylor, and Campbell H. Thompson. "A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis." Nutrients 14, no. 20 (2022): 4406. http://dx.doi.org/10.3390/nu14204406.

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This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017–August 2021 for ≥30 days with pre-post data collected for ≥1 key outcome variable (body weight and HbA1c) were included in the analysis. Average participation duration was 218 ± 207 days with 5.4 ± 3.9 reported consultation visits. Body weight reduced from 92.3 ± 23.0 to 86.3 ± 21.1 kg (n = 506, p < 0.
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13

Laseter, Isaac H., Steven L. Finkelstein, Micaela J. Bagley та ін. "A Search for Lensed Lyα Emitters within the Early HETDEX Data Set". Astrophysical Journal 940, № 1 (2022): 9. http://dx.doi.org/10.3847/1538-4357/ac9186.

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Abstract The Hobby–Eberly Telescope Dark Energy Experiment (HETDEX) is a large-volume spectroscopic survey without preselection of sources, searching ∼540 deg2 for Lyα emitting galaxies (LAEs) at 1.9 < z < 3.5. Taking advantage of such a wide-volume survey, we perform a pilot study using early HETDEX data to search for lensed Lyα emitters (LAEs). After performing a proof of concept using a previously known lensed LAE covered by HETDEX, we perform a search for previously unknown lensed LAEs in the HETDEX spectroscopic sample. We present a catalog of 26 potential LAEs lensed by foreground,
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14

Firmansyah, Awang, Hapsari Peni Agustin Tjahyaningtijas, Ahmad Hafizh Ainur Rasy, Agung Prijo Budijono, Andika Bayu Putro, and I. Wayan Valentino Eka Putra. "Correlation Between Limb Length and Muscle Mass of The Lower Extremity." ACPES Journal of Physical Education, Sport, and Health (AJPESH) 4, no. 2 (2024): 150–54. https://doi.org/10.15294/ajpesh.v4i2.21461.

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Introduction: Muscle mass has a contribution to body strength. One third of the human body is part of the lower extremity. The limbs are part of the lower extremity. This study aims to investigate the length of the limb with muscle mass. Methods: Cross-sectional study with the subjects of this study were 39 students (12 females and 27 males) with male characteristics (age 20.03±0.7, height 168±5.46, weight 61.92±10.98, BMI 22±4.24) while in women (age 20.16±0.83, height 158.83.3±5.13, weight 54.7±12.02, BMI 21.65±4.51). Pearson correlation from SPSS version 26 with a significance level of P-va
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15

Mukherjee, Akash, Denai R. Milton, Elias Jabbour, et al. "Allogeneic stem cell transplantation (AlloSCT) for patients (pts) with acute leukemia following venetoclax-based therapy." Journal of Clinical Oncology 37, no. 15_suppl (2019): 7047. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.7047.

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7047 Background: BCL-2 inhibitor Ven has shown a promising benefit in pts with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). There is paucity of information about the safety and efficacy of alloSCT post Ven. Methods: We conducted a retrospective analysis of 35 AML/ALL pts who received alloSCT following Ven-based therapies between 2013-2018 at MDA. Results: Median age at alloSCT was 60 years and 15 (43%) pts had an age-adjusted HCT-CI score ≥ 4. Disease diagnosis – AML (n = 31; 89%), ALL (n = 4; 11%). Disease status at transplant was CR1 (n = 17; 49%), CR2/CR3 (n = 9; 26%
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16

Polupanov, A. G., T. B. Zalova, F. T. Rysmatova, M. T. Duishenalieva, T. A. Romanova, and A. S. Dzhumagulova. "Relationship of tumor necrosis factor-alpha and interleukin-10 with the development of fatal and non-fatal complications in patients with essential hypertension during mid-term follow-up." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 25, no. 5 (2020): 540–48. http://dx.doi.org/10.18705/1607-419x-2019-25-5-540-548.

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Objective. To study the association of tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) with the development of fatal and non-fatal complications in patients with essential hypertension (EHTN) in the process of mid-term follow-up.Design and methods. 90 patients with EHTN aged 40 to 75 years (average age 56,4 ± 8,1 years) were observed, including 47 women and 43 men. The follow-up period ranged from 20 to 26 months (median observation — 24 months). At baseline, we assessed height, weight, body mass index, waist circumference, blood pressure and heart rate, fasting glucose, serum c
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17

Brandenburg, R. L., and P. T. Hertl. "Alfalfa Weevil Control on Alfalfa, North Carolina, 1990." Insecticide and Acaricide Tests 16, no. 1 (1991): 126–27. http://dx.doi.org/10.1093/iat/16.1.126a.

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Abstract A 6-yr-old stand of Cimmaron alfalfa located 15 miles south of Raleigh was used as a test site. Soil type was a sandy loam with 0.7% humic matter and a pH of 5.7. Plots were 20 × 20 and arranged in a randomized complete block with 4 replicates for each treatment. Treatments were applied on 6 Mar using a CO2-pressurized backpack sprayer using 8002 nozzles mounted on a hand-held boom delivering 30 gal/acre at 40 psi. Conditions at time of application were sunny and 70°F. Pretreatment counts were taken on 6 Mar and averaged 6.67 larvae/stem. Treatments were evaluated on 9, 12, 16, 23, 26
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18

Rutschman, D. H., W. Olivera, and J. I. Sznajder. "Active transport and passive liquid movement in isolated perfused rat lungs." Journal of Applied Physiology 75, no. 4 (1993): 1574–80. http://dx.doi.org/10.1152/jappl.1993.75.4.1574.

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The isolated perfused liquid-filled rat lung in a "pleural bath" was the model used to study liquid exchange across the lung epithelium. Active transport and passive solute movement between the air space, the vascular perfusate, and the bath result in concentration changes of the three markers (Evans blue-tagged albumin, 22Na+, and [3H]mannitol) instilled in the air space. A mathematical model was developed to estimate the active and passive solute transports and to interpret the results. Rat lungs were perfused at left atrial and pulmonary arterial pressures of 0 and 8 mmHg, respectively. Six
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Amin, A., V. DePril, O. Hamid, et al. "Evaluation of the effect of systemic corticosteroids for the treatment of immune-related adverse events (irAEs) on the development or maintenance of ipilimumab clinical activity." Journal of Clinical Oncology 27, no. 15_suppl (2009): 9037. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.9037.

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9037 Background: Ipilimumab, a fully human monoclonal antibody that inhibits cytotoxic T-lymphocyte antigen-4, has clinical activity at 10 mg/kg in patients (pts) with advanced melanoma. Most grade 3/4 immune-related adverse events (irAEs) associated with ipilimumab can be managed with systemic corticosteroids following established treatment guidelines. However, little has been reported about the effects of corticosteroids used to treat irAEs on ipilimumab antitumor responses. Methods: Across 3 phase II studies with 10 mg/kg ipilimumab monotherapy in advanced melanoma (CA184008, 022, and 007;
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Abdullah, Hend H. A. M., Nadia Amanzougaghene, Handi Dahmana, Meriem Louni, Didier Raoult, and Oleg Mediannikov. "Multiple vector-borne pathogens of domestic animals in Egypt." PLOS Neglected Tropical Diseases 15, no. 9 (2021): e0009767. http://dx.doi.org/10.1371/journal.pntd.0009767.

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Vector Borne Diseases (VBDs) are considered emerging and re-emerging diseases that represent a global burden. The aim of this study was to explore and characterize vector-borne pathogens in different domestic animal hosts in Egypt. A total of 557 blood samples were collected from different animals using a convenience sampling strategy (203 dogs, 149 camels, 88 cattle, 26 buffaloes, 58 sheep and 33 goats). All samples were tested for multiple pathogens using quantitative PCR and standard PCR coupled with sequencing. We identified Theileria annulata and Babesia bigemina in cattle (15.9 and 1.1%,
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Douglass, Caitlin H., Cassandra J. C. Wright, Angela C. Davis, and Megan S. C. Lim. "Correlates of in-person and technology-facilitated sexual harassment from an online survey among young Australians." Sexual Health 15, no. 4 (2018): 361. http://dx.doi.org/10.1071/sh17208.

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Background Technology-facilitated sexual harassment is an emerging phenomenon. This study investigates correlates of sexual harassment among young Australians. Methods: Participants aged 15-29 were recruited for an online survey. Participants reported how often in the past year they experienced sexual harassment in person, via phone, social media and dating apps. Correlates of in-person and technology-facilitated sexual harassment were identified using logistic regression. Results: Of all participants (n = 1272, 70% female), two-thirds reported sexual harassment in person, 34% through social m
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Schindler, Jan-Torge, Eduardo Bañados, Thomas Connor, et al. "The Pan-STARRS1 z > 5.6 Quasar Survey. III. The z ≈ 6 Quasar Luminosity Function." Astrophysical Journal 943, no. 1 (2023): 67. http://dx.doi.org/10.3847/1538-4357/aca7ca.

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Abstract We present the z ≈ 6 type-1 quasar luminosity function (QLF), based on the Pan-STARRS1 (PS1) quasar survey. The PS1 sample includes 125 quasars at z ≈ 5.7–6.2, with −28 ≲ M 1450 ≲ −25. With the addition of 48 fainter quasars from the SHELLQs survey, we evaluate the z ≈ 6 QLF over −28 ≲ M 1450 ≲ −22. Adopting a double power law with an exponential evolution of the quasar density (Φ(z) ∝ 10 k(z−6); k = −0.7), we use a maximum likelihood method to model our data. We find a break magnitude of M * = − 26.38 − 0.60 + 0.79 mag , a faint-end slope of α = − 1.70 − 0.19 + 0.29 , and a steep bri
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Komrokji, Rami S., Amy E. DeZern, Katrina Zell, et al. "Validation of International Working Group (IWG) Response Criteria in Higher-Risk Myelodysplastic Syndromes (MDS): A Report on Behalf of the MDS Clinical Research Consortium (MDS CRC)." Blood 126, no. 23 (2015): 909. http://dx.doi.org/10.1182/blood.v126.23.909.909.

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Introduction The primary goal for treatment of higher-risk MDS patients (pts) is to improve overall survival (OS) and delay acute myeloid leukemia (AML) evolution. The IWG 2006 response criteria are used in clinical trials and in clinical practice for assessing efficacy of MDS therapies. These criteria were originally proposed by an international group of experts based on available data and consensus. In an ad hoc landmark analysis of the AZA-001 study using the 2006 IWG criteria, pts who achieved hematological improvement (HI), complete response (CR), marrow CR (mCR), or partial response (PR)
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Zhang, Peiyang, Baicheng Wang, Xiaowei Zhang, et al. "Suprapubic Liposuction With a Modified Devine’s Technique for Buried Penis Release in Adults." Plastic Surgery 28, no. 3 (2020): 172–78. http://dx.doi.org/10.1177/2292550320903440.

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Background: With the increasing prevalence of overweight and obesity, adult-acquired buried penis is more common in recent years. Many surgical techniques have been reported. However, none is the gold standard. Objective: To evaluate the safety and efficacy of combining suprapubic liposuction and modified Devine’s technique for penile lengthening in adult patients with buried penis due to obesity Methods: From September 2015 to June 2018, 26 consecutive suitable patients (mean age: 33 ± 5.7 years, mean body mass index: 29 ± 5.4 kg/m2) with a buried penis received suprapubic liposuction and mod
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Gebrekidan, Gebreabzgi Teklay, and Abiye Mulugeta Alemu. "Profile of secondary glaucoma in a resource-limited setup: institution-based cross- sectional study." Ethiopian Medical Journal 62, no. 3 (2024): 173–79. http://dx.doi.org/10.4314/emj.v62i3.4.

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Background: Prevalence and types of secondary glaucoma varies between countries. This study aims to determine the current clinical profile, proportion, and causes of various types of secondary glaucoma in newly diagnosed glaucoma patients at Menelik II Specialized Hospital.Methods: This hospital-based cross-sectional descriptive study was conducted at a glaucoma clinic between May 1 and July 31, 2022. All newly diagnosed secondary glaucoma patients aged 18 years and above were included. A structured questionnaire comprising socio-demographic data, history, visual acuity, intraocular pressure,
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Andrioli, Kleber Gustavo, and Paulo Cesar Sentelhas. "Brazilian maize genotypes sensitivity to water deficit estimated through a simple crop yield model." Pesquisa Agropecuária Brasileira 44, no. 7 (2009): 653–60. http://dx.doi.org/10.1590/s0100-204x2009000700001.

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The objective of this work was to determine the sensitivity of maize (Zea mays) genotypes to water deficit, using a simple agrometeorological crop yield model. Crop actual yield and agronomic data of 26 genotypes were obtained from the Maize National Assays carried out in ten locations, in four Brazilian states, from 1998 to 2006. Weather information for each experimental location and period were obtained from the closest weather station. Water deficit sensitivity index (Ky) was determined using the crop yield depletion model. Genotypes can be divided into two groups according to their resista
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Wenk, Manuel, Christina Massoth, Daniel M. Pöpping, and Michael Möllmann. "Feasibility of Cervical Epidural Anesthesia for Breast Cancer Surgery." Anesthesiology Research and Practice 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/7024924.

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Background. Effects of perioperative cervical level neuraxial blocks on the dissemination of cancer metastases have become a matter of substantial interest. However, experience with these catheters has been limited and data on feasibility and efficacy is sparse. Methods. Data from 39 patients scheduled to undergo breast cancer surgery while awake with a cervical epidural alone was retrospectively analyzed. Results. In 26 patients (66,7%, 95% CI 51,7–81,7) the cervical epidural catheter was sufficient for surgery. In one patient (2.6%, 95% CI 0–7.6) identification of the epidural space was not
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Kolosov, Alexey V., S. I. Achkasov, E. S. Surovegin, R. Yu Khryukin, A. A. Likutov, and O. I. Sushkov. "Efficacy and safety of hybrid laparo-endoscopic surgery for colon tumors (systematic review and meta-analysis)." Koloproktologia 22, no. 4 (2023): 135–46. http://dx.doi.org/10.33878/2073-7556-2023-22-4-135-146.

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Aim: to compare the efficacy and safety of hybrid laparo-endoscopic operations and laparoscopic segmental colectomy for benign endoscopically non-removable colorectal tumors.Materials and Methods: systematic review and meta-analysis included 17 studies which evaluate the results of hybrid laparo-endoscopic procedure (main group) and laparoscopic segmental colectomy (control group). The study included 835 patients — 517 in main group and 318 controls.Results: operation time was significantly lower in main than in control group (mean difference = −38,7 minutes; 95% CI: −51,4 — −26, p < 0,0000
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Powles, Thomas, Ajjai Shivaram Alva, Mustafa Ozguroglu, et al. "Post hoc pooled analysis of first-line (1L) pembrolizumab (pembro) for advanced urothelial carcinoma (UC): Outcomes by response at week nine in KEYNOTE-052 and KEYNOTE-361." Journal of Clinical Oncology 40, no. 6_suppl (2022): 519. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.519.

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519 Background: Pembro is a 1L treatment for cisplatin-ineligible pts with UC. This post hoc landmark analysis evaluated clinical outcomes by response at 9 wk to 1L pembro monotherapy in pts with advanced/unresectable or metastatic UC from the single-arm phase 2 KEYNOTE-052 (NCT02335424) and the randomized phase 3 KEYNOTE-361 (NCT02853305) trials. Methods: Cisplatin-ineligible pts with advanced UC were enrolled in KEYNOTE-052 and received pembro (200 mg Q3W for ≤2 y). Platinum-eligible pts with advanced UC who had not previously received systemic chemotherapy (chemo) were enrolled in KEYNOTE-3
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Reichert, Dorothea, Nikolaus Scheper, Dirk Müller-Wieland, et al. "Ambulante Diabetesversorgung in Deutschland – Ergebnisse einer Strukturerhebung in diabetologischen Praxen und Einrichtungen." Diabetologie und Stoffwechsel 13, no. 02 (2018): 167–73. http://dx.doi.org/10.1055/a-0578-8296.

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Zusammenfassung Hintergrund Die Zahl der Erkrankungen an Diabetes mellitus nimmt in Deutschland zu. Um den Status quo der ambulanten spezialisierten Diabetesversorgung bundesweit zu untersuchen, wurde eine Umfrage in diabetologischen Praxen und Einrichtungen bezüglich ihrer Strukturen, der Organisation und der Qualifikation der ärztlichen sowie nichtärztlichen Mitarbeiter durchgeführt. Methode Ärzte des Bundesverbandes Niedergelassener Diabetologen (BVND) und der Deutschen Diabetes Gesellschaft (DDG) erhielten einen Fragebogen. Der Befragungszeitraum umfasste 3 Monate. Die Auswertung der Frage
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Bailey, Stephen J., Jonathan Fulford, Anni Vanhatalo, et al. "Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans." Journal of Applied Physiology 109, no. 1 (2010): 135–48. http://dx.doi.org/10.1152/japplphysiol.00046.2010.

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The purpose of this study was to elucidate the mechanistic bases for the reported reduction in the O2cost of exercise following short-term dietary nitrate (NO3−) supplementation. In a randomized, double-blind, crossover study, seven men (aged 19–38 yr) consumed 500 ml/day of either nitrate-rich beetroot juice (BR, 5.1 mmol of NO3−/day) or placebo (PL, with negligible nitrate content) for 6 consecutive days, and completed a series of low-intensity and high-intensity “step” exercise tests on the last 3 days for the determination of the muscle metabolic (using31P-MRS) and pulmonary oxygen uptake
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32

Teplenky, M. P., E. V. Oleinikov, and V. S. Bunov. "Hip reconstruction in patients with ischemic deformity of the proximal femur and associated acetabular dysplasia." Genij Ortopedii 26, no. 4 (2020): 502–7. http://dx.doi.org/10.18019/1028-4427-2020-26-4-502-507.

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Introduction Acetabular dysplasia associated with ischemic deformity of the proximal femur leads to significant functional limitations and progressive hip osteoarthritis (OA). The best surgical approach, the timing and the volume of surgery are still controversial. Material and methods Outcomes of 32 patients with ischemic hip deformity were reviewed. The mean age at the time of surgery was 15.8 ± 0.7 (range, 12–24) years. The mean follow-up period was 4.2 ± 0.4 years. Clinical outcomes were measured using the Merle d'Aubigné-Postel, Tönnis, Severin scoring scales and the grading system develo
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33

Barinov, Sergey Vladimirovich, Oksana Vyacheslavovna Lazareva, Boris Vasil’yevich Korneev, et al. "To the matter about operational treatment of benign neoplasms of ovaries during pregnancy." Journal of obstetrics and women's diseases 64, no. 4 (2015): 13–20. http://dx.doi.org/10.17816/jowd64413-20.

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Purposes and tasks. To improve the result of treatment of benign ovarian tumor during pregnancy using information of a complex comparative analysis of surgical interventions performed by laparoscopy and laparotomy. Materials and methods. We examined 69 pregnant women who undergoing treatment of benign ovarian tumors by laparoscopic and laparotomic surgery. The analysis of clinical data, postoperative pain, postoperative complications and statistic assess were performed. Results. The average age of pregnant women in laparoscopy group was 26 ± 0,5 years and 29 ± 0,7 years in laparotomy group. Th
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Upadhyaya, Santhosh, Olivia Campagne, Giles W. Robinson, et al. "Phase II study of alisertib as a single agent in recurrent or progressive atypical teratoid rhabdoid tumors." Journal of Clinical Oncology 38, no. 15_suppl (2020): 10542. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.10542.

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10542 Background: We conducted a Phase II study of alisertib, small-molecule inhibitor of Aurora A kinase, as single-agent treatment in patients < 22 y with recurrent or progressive atypical teratoid rhabdoid tumors (ATRT) (NCT02114229). Methods: Patients received alisertib once daily [80 mg/m2 (enteric-coated tablets) or 60 mg/m2 (liquid)] on Days 1–7 of a 21-day cycle for 2 y or until progressive disease (PD). Therapy was considered promising if ≥10 patients were without PD by MR imaging at 12 wk. Molecular groups were determined using Infinium Methylation EPIC BeadChips and the Heidelber
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35

Wei, Chiming, and John C. Burnett. "Inhibition by calcium antagonism of circulating and renal endothelin in experimental congestive heart failure." American Journal of Physiology-Heart and Circulatory Physiology 278, no. 1 (2000): H263—H268. http://dx.doi.org/10.1152/ajpheart.2000.278.1.h263.

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Endothelin (ET) is a potent vasoconstrictor and sodium-regulating peptide whose tissue and plasma concentrations are increased in congestive heart failure (CHF). ET may mediate its vasoconstrictor and sodium-regulatory actions secondary to an increase in intracellular calcium. Calcium influx may augment ET synthesis. Although felodipine, a dihydropyridine calcium-channel antagonist, is effective in reducing vascular resistance in generalized vasoconstriction, its actions in CHF on circulating and local tissue ET remain undefined. The current studies were designed to determine the modulating ac
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Galanis, Evanthia, Kurt A. Jaeckle, Matthew J. Maurer, et al. "Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study." Journal of Clinical Oncology 27, no. 12 (2009): 2052–58. http://dx.doi.org/10.1200/jco.2008.19.0694.

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PurposeVorinostat, a histone deacetylase inhibitor, represents a rational therapeutic target in glioblastoma multiforme (GBM).Patients and MethodsPatients with recurrent GBM who had received one or fewer chemotherapy regimens for progressive disease were eligible. Vorinostat was administered at a dose of 200 mg orally twice a day for 14 days, followed by a 7-day rest period.ResultsA total of 66 patients were treated. Grade 3 or worse nonhematologic toxicity occurred in 26% of patients and consisted mainly of fatigue (17%), dehydration (6%), and hypernatremia (5%); grade 3 or worse hematologic
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Baines, A. D., R. Drangova, and C. Hatcher. "Dopamine production by isolated glomeruli and tubules from rat kidneys." Canadian Journal of Physiology and Pharmacology 63, no. 2 (1985): 155–58. http://dx.doi.org/10.1139/y85-027.

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To locate the sites of dopamine (D) production in rat renal cortex, we separated glomeruli and proximal tubules by sieving or centrifugation in Percoll after collagenase digestion. After centrifugation layer I contained 60–80% glomeruli and 20–40% tubule fragments, half of which did not stain with alkaline phosphatase, layer II contained 0–5% glomeruli, 10–25% tubule fragments other than proximal tubules, and 70–85% proximal tubule fragments. Layer IV contained 85–95% proximal tubules. Gluconeogenic rates were (micromoles per hour per gram wet weight) as follows: I, 4 ± 1; II, 7 ± 2; and IV, 1
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38

Wennström, Ulfstand, Urban Bergsten, and Jan-Erik Nilsson. "Early seedling growth of Pinus sylvestris after sowing with a mixture of stand and orchard seed in dense spacings." Canadian Journal of Forest Research 31, no. 7 (2001): 1184–94. http://dx.doi.org/10.1139/x01-050.

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Effects on early seedling growth of seeding stand and orchard seed of Pinus sylvestris L. in different mixtures (100, 75, 50, 25, and 0% of orchard seed) at 4-cm target spacing were quantified in one nursery and one field experiment during a 2- and 5-year period, respectively. In the field experiment, 50% mixtures at 8- and 12-cm target spacing were also studied. Seedlings from orchard seeds (OS) had in general higher growth rate than seedlings from stand seed (SS). In the nursery experiment, OS were 25% taller, had 41% larger above-soil biomass, and 18% larger root biomass than SS after 2 yea
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39

Diker, Gürkan, Artur Struzik, Sadi Ön, and Raif Zileli. "The Relationship between the Hamstring-to-Quadriceps Ratio and Jumping and Sprinting Abilities of Young Male Soccer Players." International Journal of Environmental Research and Public Health 19, no. 12 (2022): 7471. http://dx.doi.org/10.3390/ijerph19127471.

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The correct torque ratio between the knee joint extensor and flexor muscle groups can effectively prevent injuries to the anterior cruciate ligament and hamstring strain. However, it is unclear whether a high torque ratio of the knee joint flexor muscles to the extensor muscles is beneficial for sport performance. Therefore, the aim of the study was to investigate the relationship between the hamstring-to-quadriceps (H/Q) ratio and sprint times (10- and 30-m) and jump heights (CMJ—countermovement jump and SJ—squat jump) in soccer players. The study examined 26 young elite soccer players (age:
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Palacios-Serna, Lina Iris, Carlos Alberto Santana-Mora, David Martin Perales-Ulfe, Carlos Esteban Borrego-Rosas, and Carmen Consuelo Jaramillo-Carrion. "Psychometric analysis of the Marc Leary Social Anxiety Scale in Peruvian university students." International Journal of Innovative Research and Scientific Studies 8, no. 1 (2025): 977–85. https://doi.org/10.53894/ijirss.v8i1.4499.

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Social anxiety is currently considered a public health crisis, largely affecting several adolescents and young adults. The situation has caused worldwide concern due to the mental health of these individuals. The objective of this study is to establish the psychometric evidence of the Social Anxiety Scale in Peruvian university students. The type of study is instrumental and non-experimental. The subjects were 517 university students between the ages of 18 and 38 who participated in total (M = 20.7; SD = 2.50). The instrument used was the Marc Leary Social Anxiety Scale. The results are based
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41

Nicolini, Franck Emmanuel, Grzegorz W. Basak, Simona Soverini, et al. "Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias." Blood 118, no. 20 (2011): 5697–700. http://dx.doi.org/10.1182/blood-2011-07-367326.

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Abstract T315I+ Philadelphia chromosome–positive leukemias are inherently resistant to all licensed tyrosine kinase inhibitors, and therapeutic options remain limited. We report the outcome of allogeneic stem cell transplantation in 64 patients with documented BCR-ABLT315I mutations. Median follow-up was 52 months from mutation detection and 26 months from transplantation. At transplantation, 51.5% of patients with chronic myeloid leukemia were in the chronic phase and 4.5% were in advanced phases. Median overall survival after transplantation was 10.3 months (range 5.7 months to not reached [
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Rosenthal, Leon, and Raúl Aguilar Roblero. "507 Clinical Impression of Excessive Daytime Sleepiness (EDS) at initial Sleep Medicine (SM) consultation and its clinical correlates." Sleep 44, Supplement_2 (2021): A199—A200. http://dx.doi.org/10.1093/sleep/zsab072.506.

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Abstract Introduction EDS represents a cardinal symptom in SM. Use of subjective scales are prevalent, which have a modest correlation with the MSLT. While the Clinical Global Impression has been used in research, reports of clinical impression (CI) in medical practice are lacking. We report on the CI of EDS in a convenience sample of patients undergoing initial consultation. Methods Patients reported primary, secondary symptoms and completed the Sleep Wake Activity Inventory (SWAI) prior to Tele-Medicine consultation. A SM physician completed the assessment which included ascertainment of CI
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Tillett, W., V. Navarro-Compán, N. Booth, et al. "AB0548 EFFECTIVENESS OF IXEKIZUMAB IN PATIENTS WITH PSORIATIC ARTHRITIS: RESULTS FROM A REAL-WORLD EUROPEAN SURVEY." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1307–8. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2001.

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Background:Limited real world (RW) data are available for IL-17A blocker ixekizumab (Ixe), approved for psoriatic arthritis (PsA) in EU Feb 2018.Objectives:Describe RW outcomes for PsA patients (pts) receiving Ixe.Methods:Cross-sectional, observational study of PsA pts treated with Ixe in the 2020 Adelphi PsA Plus Program (FR, DE, ES & UK). Rheumatologists recruited the first 6 consecutive consulting Ixe pts and provided demographics, PsA manifestations, clinical measures (66 swollen joint count (SJC), 68 tender joint count (TJC), psoriasis area and severity index [PASI], body surface area
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44

Obando Camino, Maritza, Felipe Matamala, and Juan Carlos Carmona Sepúlveda. "Desarrollo morfogénico en micropropagación de semillas de Eucalyptus nitens mejoradas genéticamente." Ciencia & Investigación Forestal 19, no. 2 (2013): 29–38. http://dx.doi.org/10.52904/0718-4646.2013.403.

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Esta investigación analizó respuestas morfogénicas de semillas de cruzamientos controlados en micropropagación de Eucalyptus nitens. Se utilizó semillas de E. nitens de 6 cruzamientos controlados, para el control se utilizó mezcla familiar. Semillas estériles fueron sembradas en medio MS (1962) modificado, 100 mg/L inositol, 2% sacarosa, 0,7% agar, pH 5,7. Para la inducción de brotes múltiples y elongación utilizó medio MS (1962) modificado, 0.25 mg/L BAP y 0,01 mg/L ANA. El enraizamiento se realizó en medio MS (1962) modificado, con regulador hormonal. Las vitroplántulas fueron mantenidas a 2
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Hanhart, Joel, and Itay Chowers. "Evaluation of the Response to Ranibizumab Therapy following Bevacizumab Treatment Failure in Eyes with Diabetic Macular Edema." Case Reports in Ophthalmology 6, no. 1 (2015): 44–50. http://dx.doi.org/10.1159/000375230.

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Background/Aims: Bevacizumab and ranibizumab are routinely used to treat diabetic macular edema (DME). We aim to evaluate the usefulness of switching to ranibizumab therapy following bevacizumab treatment failure in eyes with DME. Methods: We performed a retrospective analysis of a consecutive group of patients with DME who received ranibizumab injections following the failure of bevacizumab injections. The injections were delivered following a pro re nata protocol every 4-6 weeks. The data collected included demographics, systemic and ophthalmic findings, as well as the central subfield thick
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46

Cabri, L. J., A. M. McDonald, C. J. Stanley, et al. "Palladosilicide, Pd2Si, a new mineral from the Kapalagulu Intrusion, Western Tanzania and the Bushveld Complex, South Africa." Mineralogical Magazine 79, no. 2 (2015): 295–307. http://dx.doi.org/10.1180/minmag.2015.079.2.08.

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AbstractPalladosilicide, Pd2Si, is a new mineral (IMA 2014-080) discovered in chromite-rich samples from the Kapalagulu intrusion, western Tanzania (30°03′51′′E 5°53′16′′S and 30°05′37′′E 5°54′26′′S) and from the UG-2 chromitite, Bushveld complex, South Africa. A total of 13 grains of palladosilicide, ranging in size from 0.7 to 39.1 μm (equivalent circle diameters), were found. Synthetic Pd2Si is hexagonal, space group P62m, with a = 6.496(5), c = 3.433(4) Å, V = 125.5(1) Å3, c:a = 0.529 with Z = 3. The strongest lines calculated from the powder pattern (Anderko and Schubert, 1953) are [d in
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Song, Yu-Ri, and Yun Ju Ha. "Factors influencing nursing students’ competency in nursing handover." Korean Association For Learner-Centered Curriculum And Instruction 24, no. 19 (2024): 47–58. http://dx.doi.org/10.22251/jlcci.2024.24.19.47.

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Objectives This study attempted to investigate the factors affecting nursing students' nursing handover competence and to identify the relationship between clinical decision-making ability, clinical reasoning ability, and handover self-efficacy to serve as a basis for future handover education courses for nursing students. Methods This study is a descriptive survey study. 145 nursing students The data were collected from September 26, 2023 to October 13, 2023 from 145 nursing students at a university. The data were analyzed by frequency and percentage, independent t-test, one-way ANOVA, and Pe
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48

Lazow, Margot, Andrew Trout, Christine Fuller, et al. "BIOM-42. IMMUNOHISTOCHEMICAL ASSESSMENT OF MEMBRANOUS SOMATOSTATIN TYPE 2A RECEPTOR (SST2A) EXPRESSION ACROSS HIGH-RISK PEDIATRIC CENTRAL NERVOUS SYSTEM (CNS) TUMORS." Neuro-Oncology 23, Supplement_6 (2021): vi20. http://dx.doi.org/10.1093/neuonc/noab196.073.

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Abstract INTRODUCTION 77Lu-DOTATATE, a radionuclide therapy which binds SST2A, has demonstrated efficacy in neuroendocrine tumors and evidence of CNS penetration, supporting potential expansion within pediatric neuro-oncology. Understanding the prevalence of SST2A expression across pediatric CNS tumors is essential to identify patients who may benefit from somatostatin receptor-targeted therapy and to further elucidate the oncogenic role of SST2A. METHODS SST2A immunohistochemistry (IHC) was performed on tumor specimens and interpreted by two experienced pathologists (blinded), utilizing semi-
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Goodman, Elizabeth K., Yimei Li, Alix E. Seif, et al. "Treatment Toxicity and Supportive Care Utilization in Children with Down Syndrome and Acute Lymphoid Leukemia at Free-Standing Pediatric Hospitals in the United States." Blood 124, no. 21 (2014): 553. http://dx.doi.org/10.1182/blood.v124.21.553.553.

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Abstract Introduction: Children with Down syndrome (DS) and acute lymphoid leukemia (ALL) have inferior outcomes due to increased treatment-related toxicity. In 2005 and 2006, multiple clinical trial protocols were modified to increase supportive care measures for these children; however, national supportive care utilization patterns for these patients have not been subsequently evaluated. Methods: A validated retrospective cohort of pediatric patients with ALL admitted from 1999 to 2011 was assembled from the Pediatric Health Information System (PHIS) database to examine organ toxicity, sepsi
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Ingle, J., D. Tu, L. Shepherd, M. Palmer, J. Pater, and P. Goss. "NCIC CTG MA.17: Intent to treat analysis (ITT) of randomized patients after a median follow-up of 54 months." Journal of Clinical Oncology 24, no. 18_suppl (2006): 549. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.549.

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549 Background: MA.17 evaluated letrozole (LET) or placebo (PLAC) after 5 years of tamoxifen (Tam) and showed [median follow-up 30 months (mos)] significant improvement in disease-free survival (DFS) for LET [hazard ratio (HR) 0.57, p = 0.00008]. The trial was unblinded and PLAC patients (pts) were offered LET. An ITT analysis of all outcomes, before and after unblinding, based on the original randomization was performed. Methods: A stratified log-rank test was used to compare DFS, distant (D)DFS, overall survival (OS) and incidence of contra-lateral breast cancer (CBC). The Cox regression mod
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