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1

Fisher, A. J., N. W. Schrader, and B. Klitzman. "Effects of chronic hypoxia on capillary flow and hematocrit in rat skeletal muscle." American Journal of Physiology-Heart and Circulatory Physiology 262, no. 6 (1992): H1877—H1883. http://dx.doi.org/10.1152/ajpheart.1992.262.6.h1877.

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The cremasteric microcirculation was studied in rats exposed to chronic hypoxia. Control male weanling Sprague-Dawley rats (n = 8) were raised for 42-49 days at 752 mmHg. Hypoxic rats (n = 9) were reared for 3 days at 551 mmHg, 4 days at 461 mmHg, 3 days at 371 mmHg, and 31-38 days at 311 mmHg (6,000 m). Red blood cells labeled with fluorescein isothiocyanate were injected. The exposed cremaster was observed using fluorescence microscopy. Rats acutely breathed 10, 21, and 30% O2 spontaneously in random order. Hypoxia-adapted animals had greater (P less than 0.01) red cell flux (10.6 +/- 1.0 vs
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2

Mullikin, Trey Carlton, S. Vincent Rajkumar, Angela Dispenzieri, et al. "Progression and Outcome in Patients with Biclonal Gammopathies." Blood 124, no. 21 (2014): 5699. http://dx.doi.org/10.1182/blood.v124.21.5699.5699.

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Abstract Background: Patients with monoclonal gammopathies typically have a single clone making a unique type of monoclonal protein, one heavy chain and one light chain. In a small proportion of patients, more than one (typically two) types of monoclonal protein can be seen and differ with respect to the heavy chain or light chain or both. There is limited information on the clinical course of patients with more than one monoclonal protein identified in their serum or urine. Objectives: We report outcomes of patients with more than one monoclonal protein at our institution over the past thirty
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3

Mustafa, Abu S., Knut E. A. Lundin, Robert H. Meloen, Thomas M. Shinnick, and Fredrik Oftung. "Identification of Promiscuous Epitopes from the Mycobacterial 65-Kilodalton Heat Shock Protein Recognized by Human CD4+ T Cells of the Mycobacterium lepraeMemory Repertoire." Infection and Immunity 67, no. 11 (1999): 5683–89. http://dx.doi.org/10.1128/iai.67.11.5683-5689.1999.

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ABSTRACT By using a synthetic peptide approach, we mapped epitopes from the mycobacterial 65-kDa heat shock protein (HSP65) recognized by human T cells belonging to the Mycobacterium leprae memory repertoire. A panel of HSP65 reactive CD4+ T-cell lines and clones were established from healthy donors 8 years after immunization with heat-killed M. leprae and then tested for proliferative reactivity against overlapping peptides comprising both the M. leprae and Mycobacterium tuberculosisHSP65 sequences. The results showed that the antigen-specific T-cell lines and clones established responded to
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4

Al-Hermezi, H. M. "Qandilite, a new spinel end-member, Mg2TiO4, from the Qala-Dizeh region, NE Iraq." Mineralogical Magazine 49, no. 354 (1985): 739–44. http://dx.doi.org/10.1180/minmag.1985.049.354.15.

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AbstractQandilite, a new species of the spinel group, has been found in a forsterite-rich rock in contact with a kaersutite-rich banded diorite from the Qala-Dizeh region, NE Iraq. Chemical analysis yielded MgO 29.62, FeO 10.32, MnO 0.76, Fe2O3 28.27, Al2O3 4.83, TiO2 26.41, SiO2 0.02, sum 100.23 wt. %. This analysis calculates to [(Mg1.20Ti0.60)][Mg0.12Mn0.02)(Al0.17)]O4 with a composition of Mg2TiO4 63.8, MgFe2O4 12.8, FeFe2O4 23.4 mole %. Qandilite is cubic with a = 8.4033±0014 Å; cell volume 593.40 Å3 and space group Fd3m; Z = 8. The seven strongest lines in the X-ray diffraction pattern a
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5

Pedersen, Susanne B., Steen D. Kristensen, and Anne-Mette Hvas. "Measurement of Whole Blood Platelet Aggregation by Multiplate® Aggregometry Before and during Aspirin Treatment." Blood 110, no. 11 (2007): 3895. http://dx.doi.org/10.1182/blood.v110.11.3895.3895.

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Abstract The inhibition of platelet aggregation by aspirin (ASA) is fundamental in treatment of ischemic heart disease (IHD). Several studies report findings of normal platelet aggregation despite ASA treatment in some individuals, referred to as ASA resistance (AR). It has been hypothesized that AR increases the risk of a future ischemic event. We evaluated a new impedance method for measurement of platelet aggregation, Multiplate® aggregometry (MA), and compared this method to light aggregometry ad modum Born (OPA), with reference to repeatability and detection of AR. Blood samples from 43 I
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6

Zhao, Dong-feng, Cheng-bing Qin, Qun Zhang, and Yang Chen. "Cavity Ringdown Spectroscopy of PH2Radical in 465–555 nm." Chinese Journal of Chemical Physics 24, no. 1 (2011): 8–15. http://dx.doi.org/10.1088/1674-0068/24/01/8-15.

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7

Mohand Said, M., K. Bendeddouche, F. Forestier, M. Halhal, A. Barjol, and A. Salvanet-Bouccara. "431 Des bulles sans conséquence." Journal Français d'Ophtalmologie 28 (March 2005): 272. http://dx.doi.org/10.1016/s0181-5512(05)73551-8.

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8

Xu, Yumei, Daniel Leduc, Weimin Ye, and Zengqi Zhao. "Description of Tripylella jianjuni sp. n. (Nematoda: Tripylidae) from New Zealand." Nematology 20, no. 8 (2018): 795–810. http://dx.doi.org/10.1163/15685411-00003176.

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Summary Tripylella jianjuni sp. n. (Tripylidae) is described from New Zealand. Females are characterised by a relatively long body (1743 (1675-1860) μm in the female and 1747 (1576-1979) μm in the male), outer labial setae (8-9 μm long) and cephalic setae (4-5 μm long) in a single circle, two large subventral teeth in two adjacent stomatal chambers, relatively short pharynx (b = 5.5 (5.4-5.6) in the female and 5.7 (5.3-6.1) in the male), vulva located slightly anterior to mid-body (V = 44 (43-46)), protuberant lips, and long filiform tail (461 (398-531) μm, c = 3.8 (3.3-4.2) and c′ = 23.2 (18-
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9

Zongo, P. D., J. Boutaalla, S. Bhalil, I. Masbahi, K. Daoudi, and H. Tahri. "441 Maladie de Eales : à propos de 3 cas." Journal Français d'Ophtalmologie 31 (April 2008): 145. http://dx.doi.org/10.1016/s0181-5512(08)71039-8.

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10

Benharbit, M., N. Boutimzine, B. Tnacheri Ouazzani, et al. "462 Le kyste irien congénital : à propos d’un cas." Journal Français d'Ophtalmologie 28 (March 2005): 279–80. http://dx.doi.org/10.1016/s0181-5512(05)73582-8.

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11

Ged, Yasser, Joshua Chaim, Andrea Knezevic, et al. "Alterations in DNA damage repair (DDR) genes and outcomes to systemic therapy in 225 immune-oncology (IO) versus tyrosine kinase inhibitor (TKI) treated metastatic clear cell renal cell carcinoma (mccRCC) patients (pts)." Journal of Clinical Oncology 37, no. 7_suppl (2019): 551. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.551.

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551 Background: Loss of function alterations in DDR genes including core components of mismatch repair and homologous recombination deficiency pathways are associated with tumorigenesis and may determine benefit from IO therapies as shown in colon cancer. The significance for standard IO and TKI treatments in mccRCC is unknown. Methods: Genomic data and treatment outcomes were retrospectively collected for two large cohorts of mccRCC: pts treated with pure IO therapy (cohort 1); and pts receiving first-line TKI (cohort 2). Tumor and germline DNA was subject to targeted panel testing across &gt
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12

Romano, Fred D., Stephen J. Kopp, June T. Daar, and Cynthia A. Smith. "The antiadrenergic effect of cyclopentyladenosine on myocardial contractility is reduced in vivo in diabetic rats." Canadian Journal of Physiology and Pharmacology 72, no. 10 (1994): 1245–51. http://dx.doi.org/10.1139/y94-177.

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The aim of this study was to test the hypothesis that the antiadrenergic action of adenosine is reduced in diabetes. This was determined by evaluating the effect of experimental diabetes mellitus on the in vivo myocardial antiadrenergic action of cyclopentyladenosine, an adenosine A1- receptor agonist. Changes in heart rate and ventricular performance in response to infusion of dobutamine, a β1-adrenergic agonist, were determined in the absence and presence of cyclopentyladenosine, in anesthetized, 10- to 12-week male diabetic (60 mg/kg streptozotocin), insulin-treated diabetic and control rat
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13

Burelle, X., C. Dot, O. Henckes, P. Wary, D. Meurie, and F. May. "421 Vasculopathie polypoïdale choroïdienne idiopathique et difficultés thérapeutiques : à propos d’un cas." Journal Français d'Ophtalmologie 30 (April 2007): 2S273. http://dx.doi.org/10.1016/s0181-5512(07)80234-8.

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14

Leversha, Gerry. "Music, a mathematical offering, by David J. Benson. Pp. 411. £25.99. 2007. ISBN 0-521-61999-8 (Cambridge University Press)." Mathematical Gazette 94, no. 531 (2010): 571–72. http://dx.doi.org/10.1017/s0025557200002187.

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15

Phung, Linh Dieu. "Building a stemmas with Paup v4.0 software the case of eight text variants of Ngon chi thi tap by Phung Khac Khoan." Science and Technology Development Journal 19, no. 1 (2016): 79–89. http://dx.doi.org/10.32508/stdj.v19i1.558.

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The inconsistency of the eight variants of Ngon chi thi tap by Phung Khac Khoan, (namely VHv. 1951, VHv. 1442, VHb. 264, A. 555, A. 1364, A. 431, VHv. 2163 and R 7) and the lack of copying information do not provide us with knowledge to construct a transmission diagram of variants. This study investigates the following research question: Could we construct a stemma which represents close relations among its variants? The theoretical foundation of New-Stemmatics and the support of PAUP software help us address this question. Namely, 8 variants could be categorised into 4 groups: Group 1 includi
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16

Williamson, H. G. M., and H. M. Barstad. "The Religious Polemics of Amos. Studies in the Preaching of Am 2, 7B-8; 4,1-13; 5,1-27; 6,4-7; 8,14." Vetus Testamentum 35, no. 1 (1985): 117. http://dx.doi.org/10.2307/1517873.

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17

Cooper, Helen J., Kristina Håkansson, Alan G. Marshall, et al. "Letter: The Diagnostic Value of Amino Acid Side-Chain Losses in Electron Capture Dissociation of Polypeptides. Comment on: “Can the (M.−X) Region in Electron Capture Dissociation Provide Reliable Information on Amino Acid Composition of Polypeptides?”, Eur. J. Mass Spectrom. 8, 461–469 (2002)." European Journal of Mass Spectrometry 9, no. 3 (2003): 221–22. http://dx.doi.org/10.1255/ejms.555.

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18

Schönwald, Matthias. "New Friends – Difficult Friendships: Germany and its Western Neighbours in the Postwar Era." Contemporary European History 11, no. 2 (2002): 317–32. http://dx.doi.org/10.1017/s0960777302002096.

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Daniel Gossel, Briten, Deutsche und Europa. Die Deutsche Frage in der britischen Außenpolitik 1945–1962 (Stuttgart: Steiner, 1999), 259pp., DM 88.00, ISBN 3-515-07159-8. Klaus Larres, ed., Uneasy Allies: British-German Relations and European Integration Since 1945 (Oxford:Oxford University Press, 2000) 344pp., $85.00, ISBN 0-19-829383-6. Werner Rouget, Schwierige Nachbarschaft am Rhein: Frankreich–Deutschland, ed. Ernst Weisenfeld and Joachim Bitterlich (Bonn: Bouvier, 1998), 160pp., DM 29.80 ISBN 3-416-02762-0. Friso Wielenga, Vom Feind zum Partner. Die Niederlande und Deutschland seit 1945.
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19

Brault, Gerard J. "A French Source of the Lord Marshal's Roll (1295–6)." Antiquaries Journal 73 (September 1993): 27–36. http://dx.doi.org/10.1017/s0003581500071663.

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The only surviving manuscript of the Lord Marshal's Roll (LM) is preserved in the Library of the Society of Antiquaries of London (MS 664, vol. 3, fols 19–25 [Roll 15]; Wagner 1950, 38). The original was no doubt in poor condition when this copy, a Hatton-Dugdale facsimile, was executed c. 1640. Many shields are defective, often showing silver instead of gold (e.g., LM 59, 60, 64, 68, 71, 73, 79, 82, 87, 304; similarly, silver instead of vair, LM 127, 331, 463, 554), omitting charges (LM 58, 90, 103, 434 (see below), 585), and reversing tinctures (LM 322). Other shields are blank and/or bear n
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20

Walker, Kristoffer, Patrick Taylor, and William L. Rodi. "Reviews." Leading Edge 38, no. 9 (2019): 728–30. http://dx.doi.org/10.1190/tle38090728.1.

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Subsurface Fluid Flow and Imaging with Applications for Hydrology, Reservoir Engineering, and Geophysics, by Donald Wyman Vasco and Akhil Datta-Gupta, ISBN 978-0-521-51633-4, 2016, Cambridge University Press, 364 p. Principles of Seismology, by Agustín Udías and Elisa Buforn, ISBN 978-1-107-13869-8, 2018, Cambridge University Press, 558 p. Velocities, Imaging and Waveform Inversion - The Evolution of Characterizing the Earth's Subsurface, by Ian F. Jones, ISBN 978-9-462-82253-5, 2018, EAGE, 238 p.
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21

Moudgil, Kamal D., Tammy T. Chang, Herbert Eradat, et al. "Diversification of T Cell Responses to Carboxy-terminal Determinants within the 65-kD Heat-shock Protein Is Involved in Regulation of Autoimmune Arthritis." Journal of Experimental Medicine 185, no. 7 (1997): 1307–16. http://dx.doi.org/10.1084/jem.185.7.1307.

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The T cell response to the 65-kD mycobacterial heat-shock protein (Bhsp65) has been implicated in the pathogenesis of autoimmune arthritis. Adjuvant arthritis (AA) induced in the Lewis rat (RT-1l) by injection of Mycobacterium tuberculosis serves as an experimental model for human rheumatoid arthritis (RA). However, the immunological basis of regulation of acute AA, or of susceptibility/resistance to AA is not known. We have defined the specificity of the proliferative T cell responses to Bhsp65 during the course of AA in the Lewis rat. During the early phase of the disease (6–9 d after onset
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22

Li, Xican, Xiaojian Ouyang, Rongxin Cai, and Dongfeng Chen. "3′,8″-Dimerization Enhances the Antioxidant Capacity of Flavonoids: Evidence from Acacetin and Isoginkgetin." Molecules 24, no. 11 (2019): 2039. http://dx.doi.org/10.3390/molecules24112039.

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To probe the effect of 3′,8″-dimerization on antioxidant flavonoids, acacetin and its 3′,8″-dimer isoginkgetin were comparatively analyzed using three antioxidant assays, namely, the ·O2− scavenging assay, the Cu2+ reducing assay, and the 2,2′-azino bis(3-ethylbenzothiazolin-6-sulfonic acid) radical scavenging assay. In these assays, acacetin had consistently higher IC50 values than isoginkgetin. Subsequently, the acacetin was incubated with 4-methoxy-2,2,6,6-tetramethylpiperidine-1-oxy radicals (4-methoxy-TEMPO) and then analyzed by ultra-performance liquid chromatography coupled with electro
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23

Bilal, Muhammad, Muhammad Tariq, Shafqat Ali Shah, Ammad Ali, Saad Ali, and Muhammad Ayub. "Visual Outcome of Ocular Trauma in Patients Managed at Tertiary Care Hospital." Journal of Gandhara Medical and Dental Science 8, no. 3 (2021): 35–39. http://dx.doi.org/10.37762/jgmds.8-3.193.

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 OBJECTIVES:
 To determine the visual outcome of ocular trauma in patients admitted in the ophthalmology unit.
 METHODOLOGY:
 This descriptive cross sectional study was conducted after approval of ethical committee, from June 2017 till June 2019 at Ophthalmology Department, Medical Teaching Institution, Mardan Medical Complex, Mardan (MTI-MMC). A total of 501 patients of either gender having ocular trauma were enrolled in study. Following informed written consent, detailed history, ocular examination and investigations the surgical procedure was carrie
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24

Yadava, Umedi L. "724 PB 462 PHYSICOCHEMICAL PROPERTIES OF GUAVA PRODUCED IN GEORGIA." HortScience 29, no. 5 (1994): 536g—537. http://dx.doi.org/10.21273/hortsci.29.5.536g.

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Fully developed and ripe guava (Psidium guajava L.) fruits harvested during Sept-Dec 1993, from field-grown trees which were winter protected by 6-mil clear polyethylene, were examined for physical characteristics and nutrient contents. The purpose of this study was to establish optimum harvest time, fruit yield and physical characters, and nutritional fluctuations over a five week storage time. Fruits picked at turning stage, were observed for fresh weight, fruit girth (horizontal) and height (vertical), fruit volume, and fruit surface & flesh color evaluation (L* a* b* values by chromame
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25

FAEGRI, K. "GOODY, J. The culture of flowers. Cambridge University Press, Cambridge: 1993. Pp xviii, 462 + 8 pp colour illustrations. Price: £ 13.95. ISBN: 0-521-12484-4." Archives of Natural History 21, no. 2 (1994): 255–57. http://dx.doi.org/10.3366/anh.1994.21.2.255b.

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26

Harris, Howell J. "Philip Scranton, Proprietary Capitalism: The Textile Manufacture at Philadelphia, 1800–1885 (Cambridge: Cambridge University Press, 1983, £27.50). Pp. xiii, 431. ISBN 0 521 25245 8." Journal of American Studies 19, no. 3 (1985): 448. http://dx.doi.org/10.1017/s0021875800015607.

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27

Bandres, E., N. Bitarte, F. Arias, et al. "501 POSTER Expression of microRNA-451 is associated with disease-free survival in gastric cancer patients treated with chemoradiotherapy after gastric resection." European Journal of Cancer Supplements 5, no. 4 (2007): 90. http://dx.doi.org/10.1016/s1359-6349(07)70440-8.

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28

Pokhodnya, G. S., Yu P. Breslavets, V. M. Breslavets, A. V. Kosov, and N. V. Perevozchikov. "Rearing gilts breeding with the introduction of “Elevit” feed additive into their diet." E3S Web of Conferences 282 (2021): 04010. http://dx.doi.org/10.1051/e3sconf/202128204010.

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Our studies have shown that additional introduction of feed additive “Elevit” into the rearing gilts’ diet at a dosage of 1.0; 1.5; 2.0% during their breeding from 4 to 8 months allows to increase the gilts’ live weight by 3.9; 7.0; 9.5%, respectively, with average daily gains also increasing in comparison to the control group by 6.4; 11.6; 15.7%. Also, when reaching 8 months, gilts of experimental groups exceeded their peers from the control group in heart mass by 3.2; 4.1; 6.3%; lungs - by 3.7; 4.0; 4.2%; liver - by 5.1; 5.8; 6.2%, respectively. When rearing gilts reached the age of 8 months
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29

Hewitt, Owen, Carter, et al. "The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome." Geriatrics 4, no. 4 (2019): 57. http://dx.doi.org/10.3390/geriatrics4040057.

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Background: With an ageing population, an increasing number of older adults are admitted for assessment to acute surgical units. Older adults have specific factors that may influence outcomes, one of which is delirium (acute cognitive impairment). Objectives: To establish the prevalence of delirium on admission in an older acute surgical population and its effect on mortality. Secondary outcomes investigated include hospital readmission and length of hospital stay. Method: This observational multi-centre study investigated consecutive patients, ≥65 years, admitted to the acute surgical units o
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30

Lanehart, Sonja L. "Reviews : A Biography of the English Language. 2d ed. By C. M. Millward. Fort Worth, TX: Harcourt Brace, 1996. xvi + 441. ISBN: 01-550-1645-8." Journal of English Linguistics 26, no. 1 (1998): 72–75. http://dx.doi.org/10.1177/007542429802600105.

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31

Konopleva, Marina, Damian R. Handisides, Mary Ann Richie, et al. "A Phase 1 Study Of TH-302, An Investigational Hypoxia-Targeted Drug, In Patients With Advanced Leukemias." Blood 122, no. 21 (2013): 3920. http://dx.doi.org/10.1182/blood.v122.21.3920.3920.

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Abstract Background TH-302 is a 2-nitroimidazole prodrug of the DNA alkylator bromo-isophosphoramide mustard designed to be selectively activated in hypoxic conditions. Preclinical data in mice with acute lymphoblastic leukemia (ALL) have demonstrated marked expansion of hypoxia in areas of marrow leukemia infiltrates (Benito et al., PLoS One 2011). TH-302 also exhibited specific hypoxia-dependent cytotoxicity when tested against primary ALL and acute myelogenous leukemia (AML) samples in vitro (Benito et al., ASH 2012). Based on these findings, a phase 1 study of TH-302 was designed for advan
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32

Galimova, L. F., D. I. Sadykova, E. S. Slastnikova, and D. I. Marapov. "Change in the aortic pulse wave velocity in children with familial hypercholesterolemia." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 26, no. 6 (2021): 640–47. http://dx.doi.org/10.18705/1607-419x-2020-26-6-640-647.

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Background. Familial hypercholesterolemia (FH) is the genetic disease characterized by an increase in the levels of total cholesterol and low density lipoproteins since childhood. The aim of the study was to assess arterial stiffness in children with heterozygous FH by measuring pulse wave velocity (PWV) in the aorta. Design and methods. The study involved 118 children. Of these, 60 healthy children were in the control group and 58 children with the diagnosis of heterozygous FH were included in the main group. Both groups were divided into 3 age subgroups: from 5 to 7 years old, from 8 to 12 y
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Brandstetter, Viktoria, Viktoria Neubauer, Elke Humer, Iris Kröger, and Qendrim Zebeli. "Chewing and Drinking Activity during Transition Period and Lactation in Dairy Cows Fed Partial Mixed Rations." Animals 9, no. 12 (2019): 1088. http://dx.doi.org/10.3390/ani9121088.

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Dairy cows need sufficient physically effective fibre (peNDF) in their diet to induce chewing with the latter stimulating salivation and maintaining rumen health. Thus, monitoring of chewing activity can be a non-invasive tool to assess fibre adequacy, and thus helping in the optimization of the diet. The objective of this study was to investigate and compare chewing activities of cows during transition period and in the course of lactation. Simmental dairy cows, in four different production groups such as dry period (from 8 to 6 weeks ante-calving), calving (24 h before and after calving), ea
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34

Fayad, Lea, Arvind J. Trindade, Petros C. Benias, et al. "Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass." Endoscopy 52, no. 03 (2020): 227–30. http://dx.doi.org/10.1055/a-1086-3433.

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Abstract Background Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. Methods A retrospective chart review (January – November 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch > 4 cm and/or outlet > 15 mm. Patients were scheduled for surveillance endoscopies at 8 weeks. Results 22 patients presented 10.5 years (SD 4.42) post-RYGB with w
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35

Saura Casanova, Geo. "[Reseña] Jóvenes. Inserciones y exclusiones a la escolarización y al trabajo remunerado." Revista Iberoamericana de Educación 60, no. 4 (2012): 13. http://dx.doi.org/10.35362/rie6041298.

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Silvia Vázquez y Sagrario Garay (coords.). Jóvenes. Inserciones y exclusiones a la escolarización y al trabajo remunerado. Miguel Ángel Porrúa, uat-uanl, 2011, 216 pp. isbn: 978-607-401-521-8.
 La simbiosis compuesta entre la educación y el trabajo de los jóvenes ha sido una temática abordada desde numerosas disciplinas de estudio debido a su transcendencia e interés social. La excepcionalidad de este libro que nos ocupa recae en un matiz que los diferencia de los restantes, ya que esta unión terminológica es atendida desde la conceptualización de otros dos términos aunados por la recipro
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36

Ndeye, Maurice. "Marine Reservoir Ages in Northern Senegal and Mauritania Coastal Waters." Radiocarbon 50, no. 2 (2008): 281–88. http://dx.doi.org/10.1017/s0033822200033580.

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In order to estimate the modern reservoir age of the seawater (R) and the corresponding local offset from the global marine radiocarbon calibration curve (δR) for coastal sites of Senegal and Mauritania, we analyzed pre-bomb mollusk shells collected between AD 1837 and 1945. In total, 27 shell samples were measured, including 19 from Senegal and 8 from Mauritania. The results for Senegal for the weighted mean of R is 511 ± 50 BP and δR is 176 ± 15 BP; for Mauritania, R is 421 ± 15 BP and δR is 71 ± 13 BP. While these values indicate a significant difference from the global mean value of R for
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37

Stadler, Zsofia Kinga, Anna Maio, Yelena Kemel, et al. "Targeted therapy based on germline analysis of tumor-normal sequencing (MSK-IMPACT) in a pan-cancer population." Journal of Clinical Oncology 38, no. 15_suppl (2020): 1500. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1500.

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1500 Background: Tumor mutational profiling for identification of somatic alterations for targeted treatment is increasingly being performed in advanced cancer patients (pts). We sought to assess the clinical utility of germline mutation profiling for targeted therapeutic interventions in a pan-cancer patient population. Methods: All pts who had germline genetic testing through a prospective protocol via a next-generation sequencing panel (MSK-IMPACT) were identified (N=11,975) from 2015-5/2019. The medical record of pts with likely pathogenic/pathogenic germline (LP/P) alterations in genes wi
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Peters, L. "Joseph J. Norton /Mads Andenas (eds.), Emerging Financial Markets and Secured Transactions, Kluwer Law International, London/The Hague/Boston, 1998, pp. xxviii + 559, ISBN 90-411-0675-8." Uniform Law Review - Revue de droit uniforme 5, no. 3 (2000): 634–35. http://dx.doi.org/10.1093/ulr/5.3.634-a.

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Igarashi, K., H. Ohtani, and J. Mochinaga. "Phase Diagram of the System LaCl3-CaCl2-NaCl." Zeitschrift für Naturforschung A 42, no. 12 (1987): 1421–24. http://dx.doi.org/10.1515/zna-1987-1212.

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The phase diagram of ternary system LaCl3-CaCl2-NaCl has been constructed from the phase diagrams of the three binary systems and of thirteen quasi-binary systems determined by DTA. For the binaries LaCl3-CaCl2 and CaCl2-NaCl eutectic points were observed at 651 °C , 35.1 mol% LaCl3 and at 508 °C , 49.9 mol% NaCl, respectively. For LaCl3-NaCl, a peritectic point besides the eutectic point at 545 °C , 36.1 mol% LaCl3 was found at 690 °C , 57.5 mol%, which is attributable to the formation of the peritectic compound 3 LaCl3 · NaCl. The phase diagram of the ternary system has a ternary eutetic poi
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40

Du, Chao, Yu Chun Zou, Zhi Qing Chen, Wen Kui Li, and Shan Shan Luo. "Effects of Annealing Temperature and Coating Layers on Properties of ZnO Thin Films Prepared by Sol-Gel Immerse Technique." Key Engineering Materials 697 (July 2016): 718–22. http://dx.doi.org/10.4028/www.scientific.net/kem.697.718.

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ZnO thin films is a kind of very potential semiconductor materials, due to their excellent chemical, electrical and optical properties. The effects of annealing temperature and coating layers on properties of ZnO thin films prepared by sol-gel immerse technique is studied in this work. The structure properties and optical properties were investigated by XRD, SEM and UV-Vis spectrophotometry respectively. It is found that the thin films were composed of better hexagonal wurtzite crystals with the c-axis preferred orientation by thermal annealing 550°C. With coating layers increasing from 2 laye
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Dotan, Z. A., K. Sathyamoorthy, F. J. Bianco, et al. "The probability of a positive bone scan in patients who were treated with adrogen ablasio therapy for rising PSA after radical prostatectomy." Journal of Clinical Oncology 24, no. 18_suppl (2006): 4574. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.4574.

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4574 Background: Physicians often order periodic bone scans to check for metastases in patients treated with androgen ablation therapy (ADT) for rising PSA (biochemical recurrence; BCR) following radical prostatectomy. However, most of these scans are negative. We studied patient characteristics to build a predictive model for a positive scan (+BS) in that setting. Methods: From our prostate cancer database we identified all patients with detectable PSA after radical prostatectomy that were treated by ADT for BCR only. There were 511 BS performed in patients treated with ADT for BCR. Among the
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Farooq, Saleem, Aashiq Hussain, Mushtaq A. Qurishi, Abid Hamid, and S. Koul. "Synthesis and Biological Evaluation of Novel Triazoles Linked 7-hydroxycoumarin as Potent Cytotoxic Agents." Anti-Cancer Agents in Medicinal Chemistry 18, no. 11 (2019): 1531–39. http://dx.doi.org/10.2174/1871520618666171229222956.

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Background: BacCancer is regarded as second leading cause of death worldwide. Therefore, there is a high demand for the discovery, development and improvement of novel anti-cancer agents which could efficiently prevent proliferative pathways and clonal expansion of cells. Objective: In view of this, a new series of bioactive scaffolds viz triazoles linked 7-hydroxycoumarin (1) were synthesized using click chemistry approach. Method: All the synthesized compounds were screened for cytotoxicity against a panel of seven different human cancer cell lines viz. Colon (Colo-205 and HCT-116), breast (
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Ivanovic, Milovan, I. V. Micovic, Sonja Vuckovic, et al. "The synthesis and preliminary pharmacological evaluation of racemic cis and trans 3-alkylfentanyl analogues." Journal of the Serbian Chemical Society 69, no. 7 (2004): 511–26. http://dx.doi.org/10.2298/jsc0407511i.

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A general, five step method for the synthesis of 3-alkylfentanyl analogues (i.e., cis and trans 3-alkyl-4-anilidopiperidines 6.1?6.6) has been developed. The starting N-phenethyl- 4-piperidone 1 was first converted into the cyclohexylimine derivative 2, ?-deprotonated with butyllithium and the resulting imine anion efficiently monoalkylated with primary and secondary alkyl halides. After mild acid hydrolysis, the obtained 3-alkyl-4-piperidones 3.1?3.6 were isolated in good yields (79?85 %), then condensed with aniline to form imines 4.1?4.6. Subsequent reduction of the imines (LiAlH4/THF) yiel
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Tafreshi, Alireza, Eddy Thientosapol, Mun Sem Liew, et al. "Efficacy of sorafenib in advanced renal cell carcinoma (RCC) independent of prior treatment, histology, or prognostic group." Journal of Clinical Oncology 31, no. 6_suppl (2013): 465. http://dx.doi.org/10.1200/jco.2013.31.6_suppl.465.

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465^ Background: Multiple targeted therapies have become available for RCC over the past decade. Sorafenib is an orally active multikinase inhibitor which has been shown to improve progression free survival in low-risk and intermediate-risk status advanced clear-cell RCC after previous systemic therapy. Methods: Between May 2006 and December 2010, patients with advanced RCC with either clear cell or non-clear cell histopathology who had progressed on prior systemic chemotherapy or were treatment naïve, ECOG performance status 0-2, commenced treatment with sorafenib (400-mg twice daily continuo
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MAHAFFEY, JAMES W., and IAN DWORKIN. "Imaginal Discs, the Genetic and Cellular Logic of Pattern Formation. Lewis I Held, Jr. Cambridge University Press. 2005. 461 pages. ISBN 0 521 01835 8. Price £38. (paperback). (ISBN 0521 58445 0. Price £120. (hardback) published 2002)." Genetical Research 87, no. 3 (2006): 219. http://dx.doi.org/10.1017/s0016672306238254.

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Özcan, M., C. Koolman, A. Aladag, and M. Dündar. "Effects of Different Surface Conditioning Methods on the Bond Strength of Composite Resin to Amalgam." Operative Dentistry 36, no. 3 (2011): 318–25. http://dx.doi.org/10.2341/10-294-l.

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SUMMARY Repairing amalgam restorations with composite resins using surface conditioning methods is a conservative treatment approach. This study investigated the effects of different conditioning methods that could be used for repair of amalgam fractures. Amalgam (N=96) was condensed into cavities within autopolymerizing polymethylmethacrylate (PMMA), and the exposed surface of each specimen (diameter, 6 mm; thickness, 2 mm) was ground finished. The specimens were randomly divided into nine experimental groups (n=12 per group), depending on the conditioning method used. The control group had n
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Peuskens, J. "Risperidone in the Treatment of Patients with Chronic Schizophrenia: a Multi-National, Multi-Centre, Double-Blind, Parallel-Group Study versus Haloperidol." British Journal of Psychiatry 166, no. 6 (1995): 712–26. http://dx.doi.org/10.1192/bjp.166.6.712.

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BackgroundThis study was performed in order to evaluate the short-term efficacy and safety of fixed risperidone doses compared to haloperidol.MethodIn a multi-national, parallel-group, double-blind study, patients with chronic schizophrenia (DSM–III–R) were randomly assigned to risperidone 1, 4, 8, 12 or 16 mg or haloperidol 10 mg daily for 8 weeks. Efficacy was assessed by the Positive and Negative Syndrome Scale for schizophrenia (PANSS) and clinical global impression (CGI), and safety primarily by the Extrapyramidal Symptom Rating Scale (ESRS).ResultsOne thousand three hundred and sixty-two
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Coimbra, C. R., and V. Plourde. "Abdominal surgery-induced inhibition of gastric emptying is mediated in part by interleukin-1 beta." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 270, no. 3 (1996): R556—R560. http://dx.doi.org/10.1152/ajpregu.1996.270.3.r556.

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The role of interleukin-1 beta (IL-1 beta) in abdominal surgery-induced inhibition of gastric emptying was investigated. Abdominal surgery was performed under halothane anesthesia, and 5 min later, the 20-min rate of gastric emptying was measured by the phenol red method in conscious animals. In nonoperated animals, intravenous IL-1 beta dose dependently decreased gastric emptying from 55.1 +/- 1.7% in controls to 8.0 +/- 3.5% (P < 0.05) after treatment with 1 microgram IL-1 beta. Prior administration of IL-1 beta receptor antagonist (IL-1 beta ra; 200 micrograms) completely abolished the i
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Applegate, Celia. "National Romanticism and Modern Architecture in Germany and the Scandinavian Countries. By Barbara Miller Lane. New York: Cambridge University Press. 2000. Pp. xvi + 416. $95.00. ISBN 0-521-58309-8." Central European History 35, no. 4 (2002): 627–30. http://dx.doi.org/10.1017/s0008938900002028.

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Harrison, Alan. "Book review of Assessing Business Excellence, 2nd edn, by L. J. PORTER and S. J. TANNER. (Butterworth-Heinemann, Oxford, 2003), x + 451 pp., £24.99 (paperback), ISBN 0 7506 5517 8." International Journal of Production Research 42, no. 23 (2004): 5077. http://dx.doi.org/10.1080/00207540412331299738.

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