Log in

Relevant bibliographies by topics / 559.4 21 / Journal articles

To see the other types of publications on this topic, follow the link: 559.4 21.

Journal articles on the topic '559.4 21'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic '559.4 21.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Wells, J. M., and C. Pring. "Letter to the Editor re the paper: Laparoscopic versus open incisional hernia repair. Olmi S, Scaini GC, Erba L, Croce E. Surg Endosc (2007) 21:555–559." Surgical Endoscopy 22, no. 1 (2007): 266. http://dx.doi.org/10.1007/s00464-007-9590-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Vasilieva, Lyudmila V., Yuliya V. Tatarintseva, Elena V. Gosteva, and Sergej Y. Popov. "Relationship of arterial hypertension, metabolic syndrome with vitamin D deficiency in women." Актуальные проблемы медицины 43, no. 4 (2020): 549–59. http://dx.doi.org/10.18413/2687-0940-2020-43-4-549-559.

Full text

Abstract:

Objective: To assess the relationship between vitamin D deficiency (VD) and risk factors for metabolic syndrome (MS) in postmenopausal women with arterial hypertension (AH). Materials and methods of research. The study included 46 women aged 45–65 years with amenorrhea > 12 months, having grade 1 hypertension and metabolic syndrome. Anthropometric, laboratory and instrumental data were studied. Biochemical parameters included total cholesterol (OH), HDL, triglycerides, glucose, insulin, and 25-hydroxyvitamin-D [25 (OH)D]. Daily blood pressure monitoring was performed according to the standa

APA, Harvard, Vancouver, ISO, and other styles

3

Laurita, C., and G. Mastroianni. "Projection methods for Fredholm integral equations on the real semiaxis." Journal of Integral Equations and Applications 21, no. 4 (2009): 559–96. http://dx.doi.org/10.1216/jie-2009-21-4-559.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Olarte, G. E., G. R. Arango, G. G. López, et al. "Detección precoz del cáncer de cuello uterino mediante colposcopia. Informe de 559 casos." Revista Colombiana de Obstetricia y Ginecología 46, no. 3 (1995): 201–4. http://dx.doi.org/10.18597/rcog.1680.

Full text

Abstract:

Con el propósito de efectuar diagnóstico precoz y tratamiento del cáncer de cuello uterino en el Departamento de Caldas, Colombia, S.A., se creó un grupo interdisciplinario o institucional descentralizado, que desde junio de 1989 se desplaza periódicamente y en forma continua a los Hospitales Regionales del Departamento de Caldas, para hacer actividades de prevención, educación a población de riesgo, adolescentes y detección del cáncer del cuello uterino. El ginecólogo practica colposcopia a todas las mujeres con citología anormal compatible con NIC o infección por VPH. Entre junio de 1989 y j

APA, Harvard, Vancouver, ISO, and other styles

5

Zhuravlev, A. V., and Ya A. Vevel. "Sequence composition of the Izyayu Formation (Upper Devonian–Lower Carboniferous) in the type area – the south of Tchernyshev Uplift." LITHOSPHERE (Russia) 21, no. 4 (2021): 546–59. http://dx.doi.org/10.24930/1681-9004-2021-21-4-546-559.

Full text

Abstract:

Research subject. The article considers the Famennian‑Tournaisian sequence of the South-Eastern part of the Tchernyshev Uplift (North Cis-Uralian). The sequence corresponds to the Izyayu Formation.Materials and methods. The article is focused on the clarification of the stratigraphy, composition and depositional environment of this formation. Research data about the Izyayu Formation in the type area (Izyayu River) were used. The stratigraphic framework of this study included data on conodonts, foraminifers and carbonate carbon isotopic shifts.Results. In the type area under study, the Izyayu F

APA, Harvard, Vancouver, ISO, and other styles

6

Lee, C. H., E. Y. L. Hui, Y. C. Woo, et al. "Circulating Fibroblast Growth Factor 21 Levels Predict Progressive Kidney Disease in Subjects With Type 2 Diabetes and Normoalbuminuria." Journal of Clinical Endocrinology & Metabolism 100, no. 4 (2015): 1368–75. http://dx.doi.org/10.1210/jc.2014-3465.

Full text

Abstract:

Background: Elevated fibroblast growth factor 21 (FGF21) levels have been suggested, from cross-sectional studies, as an indicator of subclinical diabetic nephropathy. We investigated whether serum FGF21 was predictive of the development of diabetic nephropathy. Method: Baseline serum FGF21 levels were measured in 1136 Chinese type 2 diabetic subjects recruited from the Hong Kong West Diabetes Registry. The role of serum FGF21 in predicting decline in estimated glomerular filtration rate (eGFR) over a median follow-up of 4 years was analyzed using Cox regression analysis. Results: At baseline,

APA, Harvard, Vancouver, ISO, and other styles

7

Barker, Alexander B., Magdalena Opazo Breton, Jo Cranwell, John Britton, and Rachael L. Murray. "Population exposure to smoking and tobacco branding in the UK reality show ‘Love Island’." Tobacco Control 27, no. 6 (2018): 709–11. http://dx.doi.org/10.1136/tobaccocontrol-2017-054125.

Full text

Abstract:

BackgroundReality television shows are popular with children and young adults; inclusion of tobacco imagery in these programmes is likely to cause smoking in these groups. Series 3 of the UK reality show Love Island, broadcast in 2017, attracted widespread media criticism for high levels of smoking depicted. We have quantified this tobacco content and estimated the UK population exposure to generic and branded tobacco imagery generated by the show.MethodsWe used 1-min interval coding to quantify actual or implied tobacco use, tobacco paraphernalia or branding, in alternate episodes of series 3

APA, Harvard, Vancouver, ISO, and other styles

8

Berthelot, Deborah, L. G. Leduc, and G. D. Ferroni. "Temperature studies of iron-oxidizing autotrophs and acidophilic heterotrophs isolated from uranium mines." Canadian Journal of Microbiology 39, no. 4 (1993): 384–88. http://dx.doi.org/10.1139/m93-056.

Full text

Abstract:

Iron-oxidizing autotrophs and acidophilic heterotrophs were quantified at an incubation temperature of 18 °C in several samples obtained from the bioleaching areas of two uranium mines in Ontario, Canada. All samples were mine-water samples with temperatures in the range 13–18 °C. Iron-oxidizing autotrophs ranged from 2683 ± 377 to 245 000 ± 20 205 colony-forming units∙mL−1 and were always numerically superior to acidophilic heterotrophs, which ranged from 40 ± 8 to 9650 ± 161 colony-forming units∙mL−1. For each sample, approximately 20 isolates of each nutritional group were examined for the

APA, Harvard, Vancouver, ISO, and other styles

9

Smalley, Stephen R., Jacqueline K. Benedetti, Daniel G. Haller, et al. "Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection." Journal of Clinical Oncology 30, no. 19 (2012): 2327–33. http://dx.doi.org/10.1200/jco.2011.36.7136.

Full text

Abstract:

Purpose Surgical resection of gastric cancer has produced suboptimal survival despite multiple randomized trials that used postoperative chemotherapy or more aggressive surgical procedures. We performed a randomized phase III trial of postoperative radiochemotherapy in those at moderate risk of locoregional failure (LRF) following surgery. We originally reported results with 4-year median follow-up. This update, with a more than 10-year median follow-up, presents data on failure patterns and second malignancies and explores selected subset analyses. Patients and Methods In all, 559 patients wi

APA, Harvard, Vancouver, ISO, and other styles

10

Fidler, M. J., A. Argiris, J. D. Patel, et al. "Gastrointestinal hemorrhage in advanced non-small cell lung cancer (NSCLC) patients treated with erlotinib and celecoxib." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7172. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7172.

Full text

Abstract:

7172 Background: Erlotinib (E) was associated with superior survival in a phase III trial of previously treated advanced NSCLC patients (pts). Celecoxib (C) has been shown to potentiate the apoptotic and growth inhibitory effects of E in pre-clinical models. Methods: This was a phase II trial of E plus C in advanced NSCLC pts that failed one prior chemotherapy regimen. Primary endpoint: efficacy; secondary endpoint: toxicity. Pts received C (400mg b.i.d.) and E (150mg daily) until disease progression. Planned accrual: 40 pts. Results: 26 pts with stage IIIB/IV NSCLC were enrolled. Patient (pt)

APA, Harvard, Vancouver, ISO, and other styles

11

Schjesvold, Fredrik, Meletios A. Dimopoulos, Meral Beksac, et al. "Pomalidomide, bortezomib, and dexamethasone (PVd) in lenalidomide (LEN)-pretreated relapsed refractory multiple myeloma: Subanalysis of patients with renal impairment in OPTIMISMM." Journal of Clinical Oncology 38, no. 15_suppl (2020): e20562-e20562. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e20562.

Full text

Abstract:

e20562 Background: Upfront LEN until disease progression is a standard treatment (Tx) in multiple myeloma (MM). Data are limited on optimal Tx after first-line LEN, especially in LEN-refractory patients (pts), a growing population. In OPTIMISMM (phase 3, NCT01734928), PVd significantly improved median PFS at first relapse in relapsed refractory MM (RRMM) pts, of whom 100% were LEN pretreated and 57% were LEN refractory (median, 20.7 vs 11.6 mos; HR = 0.54 [95% CI, 0.36-0.82]; P = .0027) vs Vd (Richardson, 2019). Pd has shown efficacy and safety in RRMM pts with moderate or severe renal impairm

APA, Harvard, Vancouver, ISO, and other styles

12

Siyadatpanah, Abolghasem, Davood Anvari, Amir Emami Zeydi, et al. "A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country." Epidemiology and Health 41 (June 15, 2019): e2019024. http://dx.doi.org/10.4178/epih.e2019024.

Full text

Abstract:

Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp. hosts, as well as variation in geographical, climatic, and socio-ethnic conditions, the question of the strains or genotypes of Echinococcus spp. that are involved in human infections is important. The aim of this study was to provide a summary of the available data on genotypes of Echinococcus obtained from the Iranian populat

APA, Harvard, Vancouver, ISO, and other styles

13

Elizondo, Maria, Carlos Doti, Julio Bruetman, et al. "Efficacy of extended thrombo-prophylaxis in major abdominal surgery: What does the evidence show?" Thrombosis and Haemostasis 99, no. 06 (2008): 1104–11. http://dx.doi.org/10.1160/th07-12-0759.

Full text

Abstract:

SummaryVenous thromboembolism (VTE) is a frequent complication following major abdominal surgery. The use of low-molecular-weight heparins (LMWH) to prevent thrombotic events in these patients is a common and well documented practice. However, there is some controversy surrounding the duration of the prophylaxis, as it has been suggested that the risk persists for several weeks after surgery.The objective of this meta-analysis is to systematically review the clinical studies that compared safety and efficacy of extended use of LMWH (for three to four weeks after surgery) versus conventional in

APA, Harvard, Vancouver, ISO, and other styles

14

Kumar, Arvind, Sanjeev Lalwani, Deepak Agrawal, Ravi Rautji, and TD Dogra. "Fatal road traffic accidents and their relationship with head injuries: An epidemiological survey of five years." Indian Journal of Neurotrauma 05, no. 02 (2008): 63–67. http://dx.doi.org/10.1016/s0973-0508(08)80002-0.

Full text

Abstract:

AbstractIn depth studies of fatal vehicular accidents provide valuable data for implementing effective emergency services to reduce the trauma related mortality and strengthening legal measures in peak hours of fatal accidents. We aimed to study, pattern of injuries especially fatal traumatic brain injuries occurring in vehicular accidents. Postmortem reports and clinical records of victims of road traffic accident autopsied during the period of 2001–2005 at Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, were analyzed retrospectively. Out of

APA, Harvard, Vancouver, ISO, and other styles

15

Dziadziuszko, R., D. T. Merrick, S. E. Witta, et al. "Insulin-like growth factor receptor 1 (IGF1R) protein expression, mRNA expression and gene copy number in operable non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 7524. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.7524.

Full text

Abstract:

7524 Background: IGF1R is a promising target for NSCLC therapy. We have evaluated IGF1R protein expression, mRNA expression and gene copy number in primary tumors from surgically treated NSCLC patients (pts) as a reference for correlative biomarker studies in trials using IGF1R inhibitors. Methods: The study included 189 consecutive NSCLC pts who underwent curative pulmonary resection. There were 24% females, 54% squamous cell carcinomas (SCC), 29% adenocarcinomas (AC), 3% large cell carcinomas, 14% other histologies; p stage I: 41%, pII: 22%, pIII: 32% and pIV: 4%. IGF1R expression was evalua

APA, Harvard, Vancouver, ISO, and other styles

16

Terlizzi, F., A. R. Babini, and R. Credi. "First Report of Stolbur Phytoplasma (16SrXII-A) on Strawberry in Northern Italy." Plant Disease 90, no. 6 (2006): 831. http://dx.doi.org/10.1094/pd-90-0831a.

Full text

Abstract:

Strawberry (Fragaria × ananassa Duch.) is one of the most important small-fruit crops in northern Italy. During the autumn of 2003, in nurseries located in Ravenna Province (Emilia-Romagna Region), a disease characterized by pronounced stunting and a very poor root system was observed in plants of the cv. Tethis. Older leaves of diseased plants were rolled upward and displayed a marked premature purple discoloration; new leaves showed size reduction, shortened petioles, chlorosis, and were generally cupped. Some of these plants were potted and kept in greenhouse conditions; the following sprin

APA, Harvard, Vancouver, ISO, and other styles

17

Michael, M., R. J. Booth, A. Milner, et al. "The utility of a specific hepatic CYP-3A4 probe (C14-Erythromycin breath test [EBT]) versus the general CYP-P450 probe (antipyrine clearance [ACL] test), for the prediction of docetaxel (D) pharmacokinetics (PK)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 2523. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.2523.

Full text

Abstract:

2523 Background: BSA-based cytotoxic dosing does not account for the individual variability in drug disposition. In the case of D, CYP 3A4 probes such as the EBT have been assessed to individualise dosing, but inconsistently. This report is the first study comparing the EBT directly with the widely available general P450 probe, the ACL test, for the prediction of D PK when given either q 21 days or weekly. Methods: Patients (pts) with pre-treated advanced malignancy suitable for D therapy, Se bilirubin≤1.0xUNL, AST≤1.5xUNL & ALP≤2.5xUNL, were entered. Prior to D therapy, pts underwent EBT

APA, Harvard, Vancouver, ISO, and other styles

18

Almhanna, Khaldoun, Jill M. Weber, Ravi Shridhar, Sarah E. Hoffe, Richard C. Karl, and Kenneth Meredith. "Effect of lymphadenectomy on survival in patients with esophageal cancer." Journal of Clinical Oncology 30, no. 4_suppl (2012): 65. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.65.

Full text

Abstract:

65 Background: The number of resected lymph nodes is associated with overall and disease-free survival in some gastrointestinal malignancies. The impact of nodal harvest during esophagectomy remains to be determined. We examined the influence of lymphadenectomy on overall survival in patients with esophageal cancer. Methods: Utilizing a prospectively maintained comprehensive esophageal cancer database we identified patients who underwent esophagectomy with between 1994 and 2011. The association between disease free survival (DFS), overall survival (OS) and nodal harvest was evaluated using mul

APA, Harvard, Vancouver, ISO, and other styles

19

Abla, Oussama, M. F. Khanani, J. K. Hitzler, et al. "Complications of Hyperleukocytosis and Leukapheresis in Pediatric Acute Leukemias." Blood 104, no. 11 (2004): 1963. http://dx.doi.org/10.1182/blood.v104.11.1963.1963.

Full text

Abstract:

Abstract Leukapheresis is commonly used in children with acute leukemia and hyperleukocytosis (WBC >100 x 109/L). We analyzed the frequency of early complications of hyperleukocytosis in children with acute lymphoblastic leukemia(ALL) and acute myeloid leukemia(AML) and the frequency of complications attributed to leukapheresis. We included all children with acute leukemia and hyperleukocytosis, presenting to HSC between January 1992 and May 2002. ICH/stroke, pulmonary leukostasis, acute renal failure (ARF) and death were considered severe complications of hyperleukocytosis. 61 ALL and 8 AM

APA, Harvard, Vancouver, ISO, and other styles

20

Eni, A. O., P. Lava Kumar, R. Asiedu, et al. "First Report of Cucumber mosaic virus in Yams (Dioscorea spp.) in Ghana, Togo, and Republic of Benin in West Africa." Plant Disease 92, no. 5 (2008): 833. http://dx.doi.org/10.1094/pdis-92-5-0833b.

Full text

Abstract:

Yam (Dioscorea spp., family Dioscoreaceae) is one of the most important food crops cultivated in the West African yam zone comprising the forest and savannah areas of Nigeria, Ghana, Côte d'Ivoire, Republic of Benin, and Togo, which account for more than 90% of the 4.59 million ha of yam cultivation worldwide (1). A survey was conducted in 2005 to document viruses in yams in Ghana, Togo, and the Republic of Benin. Samples (1,405) from five species of yam showing mosaic, chlorosis, and stunting as well as asymptomatic plants were tested for Dioscorea bacilliform virus (DBV, genus Badnavirus), Y

APA, Harvard, Vancouver, ISO, and other styles

21

Silva, F. N., R. B. Queiroz, A. N. Souza, et al. "First Report of a 16SrII-C Phytoplasma Associated with Asymptomatic Acid Lime (Citrus aurantifolia) in Brazil." Plant Disease 98, no. 11 (2014): 1577. http://dx.doi.org/10.1094/pdis-04-14-0431-pdn.

Full text

Abstract:

At present, the principal bacterial disease of citrus in Brazil is Huanglongbing, caused by the alpha-proteobacterium ‘Candidatus Liberibacter spp.’ (although a phytoplasma of the 16SrIX group is also associated with this disease [4]). While there is a wide diversity of phytoplasmas in crop species in Brazil (3), there have been no reports of symptoms associated with phytoplasma in Brazilian citrus. Asymptomatic infections of citrus cannot be excluded as a possibility and such plants could serve as a reservoir of phytoplasma inoculum. The aim of this study was to assess the presence of phytopl

APA, Harvard, Vancouver, ISO, and other styles

22

Mendes, Catarina, Inês Vaz Matos, Luís Ribeiro, Maria João Oliveira, Helena Cardoso, and Teresa Borges. "Hiperplasia Congénita da Suprarrenal por Deficiência de 21-Hidroxílase: Correlação Genótipo-Fenótipo." Acta Médica Portuguesa 28, no. 1 (2015): 56. http://dx.doi.org/10.20344/amp.5579.

Full text

Abstract:

<strong>Introduction:</strong> Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is one of the most frequent inborn conditions. It is caused by distinct mutations in the CYP21A2 gene and in the majority of cases the disease’s severity correlates with CYP21A2 allelic variation Our aim was to describe the mutational spectrum of CYP21A2 and evaluate genotype-phenotype correlation in a cohort of portuguese patients with 21-hydroxylase deficiency.<br /><strong>Material and Methods</strong>: Retrospective study of 22 patients with clinical diagnosis of 21-

APA, Harvard, Vancouver, ISO, and other styles

23

Agarev, Aleksey Evgenievich, Maksim Sergeevich Kovalenko, and Tatyana Davydovna Zdolnik. "RISK FACTORS OF THE DEVELOPMENT OF PRENOSOLOGICAL FORMS OF POSTPARTUM PYOINFLAMMATORY DISEASES." Avicenna Bulletin 21, no. 4 (2019): 550–54. http://dx.doi.org/10.25005/2074-0581-2019-21-4-550-554.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Danilenko, E. G., and S. V. Telegin. "LABORATORY SEPARATOR OF BULK MATERIALS." Siberian Journal of Science and Technology 21, no. 4 (2020): 550–55. http://dx.doi.org/10.31772/2587-6066-2020-21-4-550-555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Walbank, Michael B. "Notes on Attic Decrees." Annual of the British School at Athens 85 (November 1990): 435–47. http://dx.doi.org/10.1017/s0068245400015781.

Full text

Abstract:

Several fragments of 4th-century BC Athenian decree-inscriptions are discussed. Joins are made betweenIGii2. 13a and 68 andHesperia, 40, no. 3;IGii2. 257 and 300; 242 and 373; 407 andSEG32. 94;IGii2. 309 and 552; 530 and 590. Attributed to the same stele, but not joining, areIGii2. 139 and 289; 277 and 428; 540a andSEG24. 117;IGii2. 540b andHesperia, 21, no. 17;IGii2. 286 and 625; 414a and 403; 398a (+ 438) and 612; 484 and 558; 489 and 532; 495 and 709; 405 andHesperia, 4, no. 32. Other decrees discussed, mainly in light of the work of A.S. Henry on the formulae of Athenian decrees, areIGii2.

APA, Harvard, Vancouver, ISO, and other styles

26

Milic, Marina, Anand Sharma, Andrew Gogbashian, Annette Hawkins, Gordon J. S. Rustin, and Marcia Hall. "A qualitative analysis of the impact of Carboplatin AUC 10 on physical, work functioning, and bone marrow toxicity, in patients with metastatic seminoma: A single centre experience." Journal of Clinical Oncology 36, no. 6_suppl (2018): 558. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.558.

Full text

Abstract:

558 Background: We studied the efficacy, safety and tolerability of dose dense Carboplatin AUC10 chemotherapy and explored the HRQoL (health-related quality of life) in metastatic seminoma patients receiving this regimen. Methods: 46 patients with metastatic seminoma treated with Carboplatin AUC10 were identified in our centre. Carboplatin dosing at AUC 10 was used and calculated based on Calvert formula and EDTA clearance. Treatment was administered as a single dose every 21 days for 3 or 4 cycles. Response to treatment was determined by radiological imaging and serum tumour markers. Toxiciti

APA, Harvard, Vancouver, ISO, and other styles

27

Mahmodi, F., J. B. Kadir, A. Puteh, M. Y. Wong, and A. Nasehi. "First Report of Pod and Stem Blight of Lima Bean Caused by Diaporthe phaseolorum var. sojae in Malaysia." Plant Disease 97, no. 2 (2013): 287. http://dx.doi.org/10.1094/pdis-08-12-0756-pdn.

Full text

Abstract:

In July 2011, a severe outbreak of pod and stem blight was observed on lima bean (Phaseolus lunatus L.) plants grown in the Cameron Highlands, located in Pahang State, Malaysia. Disease incidence varied from 33 to 75% in different fields. Pods and stems exhibited withered, light brown to reddish brown necrotic areas. Sub-circular and brown lesions were produced on the leaves. These lesions varied in size, often reaching a diameter of 1 to 2 cm. After tissue death, numerous pycnidia were observed on the surface of the pod or stem. The pycnidia diameter varied from 155 to 495 μm, averaging 265.4

APA, Harvard, Vancouver, ISO, and other styles

28

Baklagin, V. N. "Variability of the Lake Onega ice coverage in the period 2000-2018 according to the satellite data." Ice and Snow 58, no. 4 (2018): 552–58. http://dx.doi.org/10.15356/2076-6734-2018-4-552-558.

Full text

Abstract:

Studying of characteristics of the Lake Onega ice regime and investigating of the climate inﬂuence on the formation and destruction of the ice cover requires a continuous chronological series of data on the Lake ice coverage. Ice cover is the percentage of the ice area to the total area of the lake. In 1955–1990, calculations of the ice coverage of the Lake were based on the use of the results of airborne ice reconnaissance. On average for this period, from 5 to 15 values were annually obtained, which was not enough for a comprehensive analysis of the ice coverage variability. In this paper, f

APA, Harvard, Vancouver, ISO, and other styles

29

Hughes, H., L. Hagen, and R. A. Sutton. "Liquid-chromatographic determination of 4-hydroxyproline in urine." Clinical Chemistry 32, no. 6 (1986): 1002–4. http://dx.doi.org/10.1093/clinchem/32.6.1002.

Full text

Abstract:

Abstract In this method for 4-hydroxyproline in urine, hydroxyproline is derivatized with 4-chloro-7-nitrobenzofurazan, with subsequent estimation by reversed-phase "high-performance" liquid chromatography. The ranges for excretion of free and total hydroxyproline while the subjects were ingesting unrestricted diets were 2-29 and 122-374 mumol/24 h (n = 21), respectively, with no significant sex-related difference. A comparison with results by colorimetry indicated no significant differences: mean (n = 18) concentrations (mumol/L) of hydroxyproline in urine were 180 (SD 149) by the present met

APA, Harvard, Vancouver, ISO, and other styles

30

DeMichele, Angela, Amy Sanders Clark, Daniel Heitjan, et al. "A phase II trial of an oral CDK 4/6 inhibitor, PD0332991, in advanced breast cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): 519. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.519.

Full text

Abstract:

519 Background: The G1/S checkpoint of the cell cycle is frequently dysregulated in breast cancer (BC). Initial efficacy of PD0332991, a potent oral inhibitor of cyclin-dependent kinases (CDKs) 4/6 was shown in a variety of solid tumors and in combination with letrozole in a randomized phase II trial. Methods: We performed a phase II, single arm trial of PD0332991 in women with advanced BC. The primary objectives were safety and efficacy. Eligible patients had histologically-confirmed, stage IV BC with primary or metastatic tumor positive for retinoblastoma (Rb) protein expression, measureable

APA, Harvard, Vancouver, ISO, and other styles

31

Goodsell, David S. "The Molecular Perspective: Ubiquitin and the Proteosome." Stem Cells 21, no. 4 (2003): 509–10. http://dx.doi.org/10.1634/stemcells.21-4-509.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Zhang, Li, Zheng G. Zhang, Michael Chopp, Peter J. Elliott, and Julian Adams. "Effects of PS-519 combined with thrombolytic therapy in embolic stroke in rat." Stroke 32, suppl_1 (2001): 351. http://dx.doi.org/10.1161/str.32.suppl_1.351-a.

Full text

Abstract:

P67 We evaluated the effect of a proteasome inhibitor (PS-519) which blocks the activation of NF-kB, alone or combination with thrombolysis, on ischemic cell damage after embolic stroke in rat. Male Wistar rats (n=44) were subjected to embolic middle cerebral artery (MCA) occlusion. Animals were randomly assigned into seven groups: PS-519 treatment groups (n=6 each group) were infused intravenously with PS-519(1.0 mg/kg) at 2 h, 4 h, or 6 h after MCA occlusion, respectively. Combination treatment groups (n=6 each group) PS-519(1.0 mg/kg) followed by rtPA (10 mg/kg) were administered at 2 h, 4

APA, Harvard, Vancouver, ISO, and other styles

33

Miller, Rowan, Michael-John Devlin, Nicholas Fraser Brown, et al. "Outcome of patients with advanced endometrial and cervical cancer treated in a phase 1 unit." Journal of Clinical Oncology 35, no. 15_suppl (2017): 5597. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.5597.

Full text

Abstract:

5597 Background: Patients (pts) with advanced endometrial (EC), cervical and vulval (CVC) cancer have limited therapeutic options and poor prognosis. Early phase trials may be a suitable option for pts with good performance status aided by molecular selection. We sought to determine the outcome of EC and CVC pts treated in a phase 1 unit. Methods: Medical records of pts with EC and CVC treated within an early phase trial between 2010 and 2016 were reviewed. Data comprised pt and tumor characteristics, prior therapy, trial therapy and outcome. Results: 38 pts, median age 59 years (21-74) with E

APA, Harvard, Vancouver, ISO, and other styles

34

Kuo, D. Y., S. V. Blank, B. Kobrinsky, et al. "Oxaliplatin plus paclitaxel for recurrent and metastatic cervical cancer (CC): New York Cancer Consortium Trial P5840." Journal of Clinical Oncology 25, no. 18_suppl (2007): 5549. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5549.

Full text

Abstract:

5549 Background: Although cisplatin (cis) is an effective radiosensitizer, its activity in patients (pts) with advanced and recurrent CC is disappointing. Oxaliplatin (O) might exhibit greater activity and be suitable for combination with paclitaxel (P). Methods: Pts with advanced and recurrent CC who had not received prior chemotherapy except radiosensitizing cis were treated with P 175 mg/m2 IV and O 130 mg/m2 IV every 21 d. Response (R), as determined by RECIST criteria and confirmed at 9 weeks (wk), and toxicity were primary outcomes. If R in = 8 patients (pts) of 18, accrual to 46 could e

APA, Harvard, Vancouver, ISO, and other styles

35

Koskenvesa, Perttu, Satu Mustjoki, Anu Räsänen, et al. "Imatinib Discontinuation Following a Major Molecular Response: Impact of Interferon Alpha and Leukemia Stem Cell Burden (The STOP Study)." Blood 112, no. 11 (2008): 2121. http://dx.doi.org/10.1182/blood.v112.11.2121.2121.

Full text

Abstract:

Abstract Tyrosine kinase inhibitor (TKI) imatinib mesylate (IM) is the standard of care for patients with chronic myeloid leukemia (CML). Leukemia-initiating CML stem cells are resistant to TKIs and thus it is unlikely that CML patients will be cured with IM monotherapy. Recent data indicate that in a proportion of CML patients primed with preceding interpheron alpha (IFNα) therapy, IM may be discontinued without rapid leukemia re-expansion. In the Nordic CML study group intermediate and low risk study (IR/LR, NordCML002), newly diagnosed CML patients were randomized after 3 months of IM induc

APA, Harvard, Vancouver, ISO, and other styles

36

Di Stasi, Antonio, Siok K. Tey, Yuriko Fujita, et al. "CASPALLO: Phase I Clinical Trial of Allodepleted T Cells Transduced with Inducible Caspase 9 Suicide Gene After Haploidentical Stem Cell Transplantation." Blood 116, no. 21 (2010): 559. http://dx.doi.org/10.1182/blood.v116.21.559.559.

Full text

Abstract:

Abstract Abstract 559 Adverse effects from cellular therapies may be prolonged and progressively worsen as cells expand and persist long-term, unlike most small molecule toxicities, which diminish following drug withdrawal. “Suicide genes” can be introduced into administered cells and activated – generally by a small molecule pro-drug - in the event of adverse effects. Although one such approach using a transferred Herpes Simplex Virus thymidine kinase (HSV-tk) gene may provide effective control, its mechanism of action requires interference with DNA synthesis. As a consequence, cell killing m

APA, Harvard, Vancouver, ISO, and other styles

37

Kálmán, Alajos, László Fábián, Gyula Argay, Gábor Bernáth, and Zsuzsanna Cs. Gyarmati. "Different forms of antiparallel stacking of hydrogen-bonded antidromic rings in the solid state: polymorphism with virtually the same unit cell and two-dimensional isostructurality with alternating layers." Acta Crystallographica Section B Structural Science 60, no. 6 (2004): 755–62. http://dx.doi.org/10.1107/s0108768104024553.

Full text

Abstract:

As a continuation of a systematic structural analysis of 2-hydroxycycloalkanecarboxylic acids and their carboxamide analogs, the effects of antidromic rings [Jeffrey & Saenger (1991). Hydrogen Bonding in Biological Structures. Berlin, Heidelberg: Springer Verlag] upon the layer stacking of cyclopentane and cycloheptane derivatives are compared. Determination of the structure of trans-2-hydroxycycloheptanecarboxylic acid (2) led to the discovery of two polymorphs with virtually the same unit cell [Kálmán et al. (2003). J. Am. Chem. Soc. 125, 34–35]. (i) The layer stacking of the antidromic

APA, Harvard, Vancouver, ISO, and other styles

38

Ширинян, Валерий Зармикович, А. И. Маркосян, М. А. Барышникова, Л. В. Яминова, А. Г. Львов та С. А. Габриелян. "Синтез и оценка антипролиферативной активности арил(гетарил)производных циклопентенона — аналогов комбретастатина A-4". Химико-фармацевтический журнал 51, № 10 (2017): 16–21. http://dx.doi.org/10.30906/0023-1134-2017-51-10-16-21.

Full text

Abstract:

На основе удобного синтетического протокола получен ряд ранее неизвестных ди- и три-арил(гетарил)производных циклопентенона и проведен первичный скрининг на противоопухолевую активность на 4 линиях клеток человека: Т-клеточного лейкоза (Jurkat), карциномы легких (A-549), рака кишечника (HCT-116) и аденокарциномы молочной железы (MCF-7). Найдено, что среди исследованных веществ наибольшей цитотоксичностью обладает 2-(3,4,5-триметоксифенил)-3-(4-метоксифенил)циклопент-2-ен-1-он. Однако, несмотря на его цитотоксическую активность в опытах in vitro, противоопухолевая активность на лимфоцитарный ле

APA, Harvard, Vancouver, ISO, and other styles

39

Gaziev, Javid, Antonella Isgrò, Pietro Sodani та ін. "Long-Term Outcome after Haploidentical Hematopoietic Cell Transplantation Utilizing CD34+ Selected/CD3CD19+ Depleted or Tcrαβ+/CD19+ Depleted Grafts in Pediatric Patients with Hemoglobinopathies". Blood 130, Suppl_1 (2017): 663. http://dx.doi.org/10.1182/blood.v130.suppl_1.663.663.

Full text

Abstract:

Abstract Introduction. Limited data exist regarding the role of haploidentical HCT (haplo-HCT) in hemoglobinopathies, whereas long-term outcomes and late effects among these patients are largely unknown. We compared long-term outcomes in two groups of patients underwent halpo-HCT using different in vitro depletion strategies. Methods . Fifty four consecutive patients, aged &lt;17 years, received a haploidentical (≥2 HLA-mismatched antigens) transplant for thalassemia (n=45) or sickle cell disease-SCD (Hb SS, n=7 and HbS/beta thalassemia, n=2). Among these patients 32 received CD34+ selecte

APA, Harvard, Vancouver, ISO, and other styles

40

Calais, Jeremie, Jeannine Gartmann, Wesley R. Armstrong, et al. "Overall survival after 177Lu-PSMA-617 molecular radiotherapy in patients with metastatic castrate-resistant prostate cancer: Post-hoc analysis of a prospective phase II trial." Journal of Clinical Oncology 38, no. 15_suppl (2020): 5549. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5549.

Full text

Abstract:

5549 Background: This was an open-label randomized prospective bi-centric single-arm phase II clinical trial of 177Lu-PSMA-617 molecular radiotherapy in patients with progressive metastatic castrate-resistant prostate cancer (mCRPC) conducted at University of California Los Angeles (USA) and Excel Diagnostics & Nuclear Oncology Center (Houston, TX, USA) (NCT03042312). The study was investigator-initiated under an investigational new drug approval protocol (IND#133661) with authorization of charging for investigational drug (cost-recovery, Title 21 CFR 312.8). We report here the post-hoc an

APA, Harvard, Vancouver, ISO, and other styles

41

Scott, A. P., Nancy M. Sherwood, A. V. M. Canario та Carol M. Warby. "Identification of free and conjugated steroids, including cortisol and 17α,20β-dihydroxy-4-pregnen-3-one, in the milt of Pacific herring, Clupea harengus pallasi". Canadian Journal of Zoology 69, № 1 (1991): 104–10. http://dx.doi.org/10.1139/z91-015.

Full text

Abstract:

Milt from Pacific herring (Clupea harengus pallasi) was extracted and purified on reversed-phase high-performance liquid chromatography. The fractions were radioimmunoassayed for the following free and conjugated steroids: cortisol; 17α,20β-dihydroxy-4-pregnen-3-one; 17α,20α-dihydroxy-4-pregnen-3-one; 17α,21-dihydroxy-4-pregnene-3,20-dione; 17α,20β,21-trihydroxy-4-pregnen-3-one; 17α-hydroxy-4-pregnene-3,20-dione; 3α,17α,21-trihydroxy-5β-pregnan-20-one; testosterone; 11-ketotestosterone. Fractions containing significant amounts of immunoreactive material were subjected to further purification o

APA, Harvard, Vancouver, ISO, and other styles

42

Hannah, Sean T., Bruce J. Avolio, and Fred O. Walumbwa. "Addendum to “Relationships between Authentic Leadership, Moral Courage, and Ethical and Pro-Social Behaviors”." Business Ethics Quarterly 24, no. 2 (2014): 277–79. http://dx.doi.org/10.5840/beq201453011.

Full text

Abstract:

ABSTRACT:The authors provide this addendum to the following article to provide corrections to the results reported and further explanation of the structural equation modeling techniques utilized: Sean T. Hannah, Bruce J. Avolio, and Fred O. Walumbwa, “The Relationships between Authentic Leadership, Moral Courage, and Ethical and Pro-Social Behaviors,” Business Ethics Quarterly 21:4 (October 2011): 555–78.

APA, Harvard, Vancouver, ISO, and other styles

43

Welch, S., H. Hirte, L. Elit, et al. "CA-125 response as a marker of clinical benefit in patients with recurrent ovarian cancer treated with gemcitabine and sorafenib—A trial of the PMH Phase II Consortium." Journal of Clinical Oncology 25, no. 18_suppl (2007): 5519. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5519.

Full text

Abstract:

5519 Background: Molecularly targeted agents are expected to have a cytostatic effect on cancers, thus traditional radiographic criteria for objective response may not be optimal in evaluating these agents. There is considerable preclinical rationale for the use of angiogenesis inhibitors in ovarian cancer (OC), and early phase trials of these agents have suggested activity. We have completed a phase II trial evaluating the efficacy of the combination of gemcitabine (GEM), a cytotoxic agent with activity in OC, and sorafenib (SOR), a novel mutitargeted kinase inhibitor with antiangiogenic acti

APA, Harvard, Vancouver, ISO, and other styles

44

Villarino, Elsa, Xianding Deng, Carol A. Kemper, et al. "Introduction, Transmission Dynamics, and Fate of Early Severe Acute Respiratory Syndrome Coronavirus 2 Lineages in Santa Clara County, California." Journal of Infectious Diseases 224, no. 2 (2021): 207–17. http://dx.doi.org/10.1093/infdis/jiab199.

Full text

Abstract:

Abstract We combined viral genome sequencing with contact tracing to investigate introduction and evolution of severe acute respiratory syndrome coronavirus 2 lineages in Santa Clara County, California, from 27 January to 21 March 2020. From 558 persons with coronavirus disease 2019, 101 genomes from 143 available clinical samples comprised 17 lineages, including SCC1 (n = 41), WA1 (n = 9; including the first 2 reported deaths in the United States, with postmortem diagnosis), D614G (n = 4), ancestral Wuhan Hu-1 (n = 21), and 13 others (n = 26). Public health intervention may have curtailed the

APA, Harvard, Vancouver, ISO, and other styles

45

Czekała, F. "The asymptotic distributions of statistics based on logarithms of spacings." Applicationes Mathematicae 21, no. 4 (1991): 511–19. http://dx.doi.org/10.4064/am-21-4-511-519.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Trybuła, S. "An m-vs.-n-bullets silent duel with arbitrary motion and arbitrary accuracy functions." Applicationes Mathematicae 21, no. 4 (1991): 545–54. http://dx.doi.org/10.4064/am-21-4-545-554.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Trybuła, S. "Minimax estimation of a cumulative distribution function for a special loss function." Applicationes Mathematicae 21, no. 4 (1991): 555–60. http://dx.doi.org/10.4064/am-21-4-555-560.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Fan, Hong-Yi. "A Possible Generalization of the Bargmann Space." Communications in Theoretical Physics 21, no. 4 (1994): 509–12. http://dx.doi.org/10.1088/0253-6102/21/4/509.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Cribiu, EP, M. Matejka, R. Darre, V. Durand, HM Berland, and A. Bouvet. "Identification of chromosomes involved in a Robertsonian translocation in cattle." Genetics Selection Evolution 21, no. 4 (1989): 555. http://dx.doi.org/10.1186/1297-9686-21-4-555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Ulloa-Aguirre, A., J. J. Mejia, R. Dominguez, J. Guevara-Aguirre, V. Diaz-Sánchez, and F. Larrea. "Microheterogeneity of anterior pituitary FSH in the male rat: isoelectric focusing pattern throughout sexual maturation." Journal of Endocrinology 110, no. 3 (1986): 539–49. http://dx.doi.org/10.1677/joe.0.1100539.

Full text

Abstract:

ABSTRACT Anterior pituitary glands were removed from male rats at 5, 10, 15, 18, 21, 28, 30, 40, 45, 50 and 90 days of age, and the multiple forms of FSH present within them were separated by polyacrylamide gel–isoelectric focusing (PAGE–IEF; pH range 3·0–8·0). Gel eluents were analysed for FSH content by radioimmunoassay (RIA) and a specific radioreceptor assay (RRA). All pituitaries studied exhibited one or more peaks of immunoactive FSH within a pH range of 7·0–3·0; the major peak exhibited an isoelectric point (pi) of 4·9–4·0. Between 25 and 56% of anterior pituitary FSH obtained from rats

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!