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Dissertations / Theses on the topic '55P47'

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Published: 4 June 2021
Last updated: 6 February 2022

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1

Jovanović, Dus̆ko. "Designing dependable process-oriented software a CSP-based approach /." Enschede : University of Twente [Host], 2006. http://doc.utwente.nl/55447.

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2

Rogers, Stephen Colin. "Significance of a nitric oxide reserve and its utilisation in the human circulation." Thesis, Cardiff University, 2006. http://orca.cf.ac.uk/55447/.

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Historically nitric oxide (NO) was viewed as playing a purely paracrine role in the vasculature, acting within the vicinity of its release. Today an endocrine role of NO metabolites is widely accepted, although the species accounting for the vascular regulatory function still remains in contention. The original aim of this thesis was to analyse the two main NO metabolite hypotheses (i.e., SNO-Hb and nitrite hypotheses) to provide a more comprehensive understanding of their potential significance in the human circulation. Initially this involved developing methods capable of measuring baseline
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3

Berger, Thomas. "Regional development and competitiveness : an analysis of indices of regional competitiveness." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55847/.

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There is a growing debate on the theoretical basis, how it could be conceptualised, as well as the utility and meaning of regional competitiveness. This is associated with various attempts to measure regional competitiveness with the help of composite indices for coming-up with league tables. However the measurement of regional performance has run ahead of the academic debate, such indices receive a lot of media attention, and in some cases are even used by policy-makers to support their arguments. It is therefore instructive to look at such indices in more detail to evaluate their utility fro
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4

Wrench, Christopher G. "Collisional transport of trace impurity ions and the role of the radial electric field in spherical tokamak plasmas." Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/55347/.

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The mitigation and control of impurities, or non-fuel ions, in tokamak plasmas is vital for reducing energy losses and an understanding of impurity transport is required in order to predict the performance of present and future tokamak devices. The development and application of a full orbit, test particle code to the study of the collisional transport of test impurity ions in spherical tokamak plasmas is presented. This code is tested against the standard analytic description of collisional transport in magnetised plasmas and is demonstrated to be particularly suited to the study of the tight
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5

Herbert, Amy Angharad. "Bone grafting : tissue treatment and osseointegration." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55547/.

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Bone grafts fill skeletal defects and provide a structure upon which new bone can be deposited. There is no standard method of storing bone prior to grafting, the three main storage regimes being stored fresh frozen at -80°C, gamma irradiated or freeze dried. The initial aim of this project was to determine how osteoblastic cells behaved when exposed to bone treated in the above ways. It was found that sterilisation of bone with gamma irradiation caused cell death in a number of the cells that came into contact with it. Therefore the use of gamma irradiation for grafting is contraindicated, a
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6

Urch, Jonathan Edward. "Fatty acid synthesis as a target for new antimalarials." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55947/.

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Malaria can be regarded as one of the world's worst health problems and its incidence is rising inexorably. It already accounts for the deaths of approximately three children every minute. This situation is exacerbated by the increased frequency of parasite resistance to current antimalarial agents and necessitates the development of new drugs to combat this disease P. falciparum possesses a plastid-like organelle, termed the apicoplast, which contains a small, highly reduced 35kb genome encoding tRNA, DNA polymerases and ribosomal proteins. Nuclear proteins are targeted to the apicoplast usin
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7

Schipani, Alessandro. "In silico study to understand the factors which are important for the rational design of novel inhibitors of dUTPase, an antimalarial drug target." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55647/.

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Inhibition of deoxyuridine triphosphate dUTPase, a ubiquitous enzyme and 'first line' of defence against misincorporation of uracil into DNA, is lethal in E. coll, S. cerevisiae and is also probably in a variety of other organisms including, Plasmodium spp., the causative agent of malaria. dUTPase is a potential chemotherapeutic target. An assortment of molecular modelling tools was used to take advantage of the available structural information to identify differences between the human and protozoan dUTPase enzymes. A major objective of this study was to develop, rationally, the available lead
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8

Liu, Haoling. "Self-pulsing 1050 nm quantum dot edge emitting laser diodes for optical coherence tomography." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/55047/.

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Self pulsed quantum dot lasers are proposed as a means to generate broadband emission in the 1050 nm region for optical coherence tomography applications. Existing quantum dot materials which are not intentionally designed for broad band emission are examined. Devices for self pulsation are configured with sr. it contacts. When operated without a saturable absorber the laser emits a number of discrete narrow (1 nm) modes, which merge to form a broad continuous lasing spectrum (10 nm) on application of the saturable absorber. Under a continuous drive current, a single mode ridge waveguide laser
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9

Morgan, Selyf Lloyd. "Developing the Welsh organic sector : knowledge generation and learning." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55747/.

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This research study is concerned with the role and influence of knowledge generation and learning processes in the development of Organic Agriculture in Wales. It builds on previous work which suggested that barriers to the generation and exchange of knowledge about organic agriculture between farmers and other actors in the sector were significant in inhibiting development. The thesis is predicated on the view that organic farming demands a complex treatment of knowledge and processes of learning, and that organic agriculture represents a synthesis of knowledge from a wide range of actors, kn
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10

Maddison, Kathryn. "In vivo consequences of removal of methyl CPG binding domain proteins." Thesis, Cardiff University, 2005. http://orca.cf.ac.uk/55147/.

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11

Banterle, Francesco. "Inverse tone mapping." Thesis, University of Warwick, 2009. http://wrap.warwick.ac.uk/55447/.

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The introduction of High Dynamic Range Imaging in computer graphics has produced a novelty in Imaging that can be compared to the introduction of colour photography or even more. Light can now be captured, stored, processed, and finally visualised without losing information. Moreover, new applications that can exploit physical values of the light have been introduced such as re-lighting of synthetic/real objects, or enhanced visualisation of scenes. However, these new processing and visualisation techniques cannot be applied to movies and pictures that have been produced by photography and cin
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12

Berardi, Giuseppe. "La variabilità della ripolarizzazione nelle aritmie cardiache: analisi modellistica." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/5547/.

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13

Renna, Cristiano <1983&gt. "Effetti dell'inibizione di Tanchirasi in linee cellulari di Medulloblastoma umano." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5547/.

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Tanchirasi (TNKS) è un membro della superfamiglia delle PARP (Poli ADP-Ribosio Polimerasi). TNKS è coinvolta nella stabilizzazione della subunità catalitca del complesso proteico DNA-PK (protein chinasi DNA-dipendente), la DNA-PKcs. Questa proteina è fondamentale per il corretto funzionamento del meccanismo di riparo del DNA chiamato "Saldatura Non Omologa delle Estremità" (NHEJ). La deplezione di TNKS induce una degradazione della DNA-PKcs e una maggiore sensibilità alle radiazioni ionizzanti (RI). TNKS è inoltre un regolatore negativo di axina e di conseguenza un attivatore del pathway di WN
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14

Longhi-Browne, Cassandra W. "Using Caenorhabditis elegans as a novel expression system for the generation of recombinant Teladorsagia circumcincta vaccine candidates." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5547/.

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Teladorsagia circumcincta is a common abomasal parasite of sheep in temperate regions and is one of the major causes of parasitic gastroenteritis (PGE) in growing lambs. Control of infection is achieved using anthelmintic drugs; however, this practice is rapidly becoming unsustainable due to widespread anthelmintic resistance within the T. circumcincta population. Sheep can acquire protective immunity against this parasite; immunity involves local and systemic antibodies and immune cells which can impair worm growth and fecundity and lead to expulsion of the parasites from the abomasum. Vaccin
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15

Bogaerde, Elizabeth Marie van den. "Input and interaction in deaf families." Utrecht : Amsterdam : LOT ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/55947.

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Proefschrift Universiteit van Amsterdam.<br>Omslag vermeldt: :LOT, Netherlands Graduate School of Linguistics, Landelijk[e] Onderzoekschool Taalwetenschap, en: IFOTT. - Auteursnaam op omslag: Beppie van den Bogaerde. Met lit. opg. - Met samenvatting in het Nederlands.
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16

Abreu, Estela Maria Ribeiro Gonçalves de. "Hiperuricemia e a resistência à insulina." Dissertação, Faculdade de Medicina da Universidade do Porto, 2009. http://hdl.handle.net/10216/55447.

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17

Chang, Jason Ph D. Massachusetts Institute of Technology. "Extracting orientation and scale from smoothly varying textures with application to segmentation." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/55147.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 109-112).<br>The work in this thesis focuses on two main computer vision research topic: image segmentation and texture modeling. Information theoretic measures have been applied to image segmentation algorithms for the past decade. In previous work, common measures such as mutual information or J divergence have been used. Algorithms typically differ by the measure they use and the features they us
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18

Ustun, Teoman Emre 1976. "A study of commercialization factors in a Small Business Innovation Research (SBIR) funded company." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/55247.

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Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 51-52).<br>A nation's ability to innovate is paramount for its success and survival among other nations. But capitalizing on these innovations and bringing them to the marketplace are what gives a nation its competitive edge and provide sustainable growth over time in this highly dynamic global economy. In the United States' complex innovation ecosystem, small businesses and entrepreneurs play a crucial role in inn
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19

Mahowald, Natalie Marie. "Development of a 3-dimensional chemical transport model based on observed winds and use in inverse modeling of the sources of CCl₃F." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/55047.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 1996.<br>Includes bibliographical references (p. 193-199).<br>Natalie Marie Mahowald.<br>Ph.D.
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20

Dornelles, Roberto Anderson. "Acontecimento e história nas páginas da revista Veja : uma análise das reportagens sobre o primeiro governo da ditadura civil-militar argentina (1976-1981)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/55347.

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Este trabalho procura analisar as relações entre jornalismo impresso e política numa perspectiva histórica. Especificamente, o tema da pesquisa é a cobertura jornalística de uma revista brasileira de periodicidade semanal e de circulação nacional, a revista Veja, sobre os acontecimentos sociais, políticos e militares, ocorridos durante o primeiro governo da ditadura civil-militar argentina entre os anos de 1976 e 1981. Este tema surge da constatação da importância do jornalismo impresso no processo de divulgação de informações ligadas à política, principalmente no período contemporâneo da hist
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21

Salazar, Josiane Bueno. "Modificação do efeito de exchange bias por inserção de Fe na interface IrMn/Co: tratamento térmico e irradiação iônica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/55447.

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Neste trabalho é apresentado um estudo sistemático sobre as modificações do fenômeno exchange bias (EB) quando ha a inserção de uma camada espaçadora magnética no sistema IrMn/Co, com o objetivo de melhor entender a relação interfacial deste. Foram fabricadas, via magnetron sputtering, tricamadas do tipo IrMn/Fe(tFe)/Co, onde a espessura da camada de Fe varia entre 0,25 e 1,50nm. Para a otimização do efeito de EB, as amostras foram submetidas a dois tipos de tratamento post-situ: tratamento térmico, em uma temperatura de 210 _C, na presença de um campo magnético externo de 2,1 kOe; e irradiaçã
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22

Garriga, Inarejos Rocío. "EL SILENCIO COMO LÍMITE COMPRENSIVO, COGNITIVO Y ESTRUCTURAL: UNA LECTURA ESTÉTICA EN TORNO AL ARTE CONTEMPORÁNEO." Doctoral thesis, Universitat Politècnica de València, 2015. http://hdl.handle.net/10251/55047.

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[EN] SILENCE AS UNDERSTANDING, COGNITIVE AND STRUCTURAL LIMIT: AN AESTHETIC READING ON CONTEMPORARY ART. In short, this thesis studies the concept of silence as limit of agreement after the impact caused by the two World Wars of the 20th century with the main objective of verifying the relevance of the role of this view of silence for the contemporary artistic production of the last decades of the 20th century and beginning of the 21st. In order to reach that objective, we have divided the exposition into four parts: study and taking a stance as concerns silence, silence as understanding lim
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23

Hernández, Navarro Yolanda. "PATRIMONIO INDUSTRIAL DEL EMBALSE DE BENAGÉBER:POBLADO Y COLONIA OBRERA. ANÁLISIS HISTÓRICO Y ARQUITECTÓNICO PARA SU PROTECCIÓN Y CONSERVACIÓN." Doctoral thesis, Universitat Politècnica de València, 2015. http://hdl.handle.net/10251/55847.

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[EN] Benagéber's Reservoir is a place of memory. The memory of those who suffered the loss of their homes, underwater today, the memory of who saw in the construction process the opportunity to improve their lives, who were subjected to forced works as a method of political purging. The memory of the Valencian society who saw how its thirsty soil became rich farmland, in summary, the memory of everybody. This work picks the retrospective journey through the buildings study of the village and workers colony of Benagéber, understood as marks of the past, to reconstruct part of the local history,
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24

Cornum, Lindsey Catherine. "The outer space future of blackness and indigeneity in Midnight Robber and The Moons of Palmares." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/55147.

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This thesis explores ways in which Afrofuturist and Indigenous Futurist works complicate and trouble what constitutes Indigeneity in the Americas and specifically how that Indigeneity is posed in relation to Blackness and the Black diaspora. Nalo Hopkinson’s Midnight Robber and Zainab Amadahy’s The Moons of Palmares are two texts that represent Blackness and Indigeneity in outer space settings creatively constructed from earthly histories of settler colonialism and the trans-Atlantic slave trade. By demonstrating the complex ways in which these violent processes have created the material, soci
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25

Crover, Sarah Margaret. "Stage and street : the cultural history of the early modern Thames." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/55747.

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26

Khameneifar, Farbod. "Section-specific geometric error evaluation of airfoil blades based on digitized surface data." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/55847.

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Manufactured aero-engine blades are normally inspected in sections. Given discrete section-specific data points, the related geometric error evaluation task for three-dimensional tolerances of the blades is challenging and not yet well studied by researchers. Particularly, the existing method shows limited effectiveness in detecting position error and difficulty in accurate estimation of orientation error of airfoil sections. Moreover, touch-probes on a coordinate measuring machine are traditionally used to collect sectional coordinate data, which is a lengthy process as the data is collect
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27

Narkhede, Yashdeep. "Simscape modeling of motor generator unit component for hybrid electric vehicle." Thesis, Georgia Institute of Technology, 2016. http://hdl.handle.net/1853/55047.

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The thesis introduces the user to programming in Simscape language. A permanent magnet synchronous machine torque control drive system for hybrid electric vehicles has been analyzed, programmed, using Simscape language, and tested in this thesis. The thesis walks the reader through the process of creating custom components in Simscape language explaining details and syntax of the language at every step. Important excerpts of code for all the components designed, created and used in the process are explained in the thesis and the complete code for the same is provided in the Appendix. ix
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28

Abreu, Estela Maria Ribeiro Gonçalves de. "Hiperuricemia e a resistência à insulina." Master's thesis, Faculdade de Medicina da Universidade do Porto, 2009. http://hdl.handle.net/10216/55447.

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29

Guerra, Maria Cristina Gonçalves. "O oral na sala de aula : contributos para o seu ensino em língua materna e em língua estrangeira." Master's thesis, Porto : [Edição do Autor], 2010. http://hdl.handle.net/10216/55047.

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Quer na língua materna quer na língua estrangeira, o oral tomou-se objecto de ensino. É importante que os alunos saibam expressar-se linguisticamente em distintos contextos de forma correcta e eficaz, seja em língua materna, seja em língua estrangeira. Para tal, cabe à Escola e, em particular, às aulas de língua trabalhar esta modalidade com os alunos. Todavia, não é suficiente ter um conhecimento da língua e utilizá-la, é necessário que possuam uma Competência Comunicativa, alcançada através de outras competências (competência linguística, competência sociolinguística, competência discursiva
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30

早川, 庄八, та Shohachi Hayakawa. "続日本紀宣命詔・三題について". 名古屋大学文学部, 1996. http://hdl.handle.net/2237/5547.

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31

Castellano, i. Tresserra Anna. "Origen i formació d'un monestir femení. Pedralbes al segle XIV (1327-1411)." Doctoral thesis, Universitat Autònoma de Barcelona, 1996. http://hdl.handle.net/10803/5547.

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32

Sanabria, Gaitan Gerardo D. "Alternatives impact in combatant-ship design." Thesis, Monterey, California. Naval Postgraduate School, 2011. http://hdl.handle.net/10945/5547.

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Approved for public release; distribution is unlimited.<br>This thesis continues the development of a systems methodology for the conceptual design of a medium-tonnage combatant ship for the Colombian navy. The purpose is to demonstrate the impact that different systems and operational capabilities have on overall design. The objective is to demonstrate new tools for studying tradeoffs in ship design, based on ship capability, allowing informed design-configuration decisions that enhance warfighting effectiveness over multiple missions, with explicit consideration given to combat and weapo
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33

Meyer, Francois. "Exploring the relationship between emotional intelligence, burnout and absenteeism of bus drivers in the sheduled public bus services industry." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/5547.

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Thesis (MBA (Business Management))--Stellenbosch University, 2008.<br>ENGLISH ABSTRACT: The aim of this study was to explore the relationships between emotional intelligence, burnout and absenteeism of bus drivers in the scheduled public bus services industry. A controlled inquiry of non-experimental research was used. In addition, correlational and multivariate research, as a form of relational research, was employed to explore the relationships between the three constructs. The constructs were defined as follows: emotional intelligence as the basic capacity of a person to identify and
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34

Bornman, Mathys Johannes. "Adolessente se geloofsoortuiging en etiese besluitnemingsraamwerk met betrekking tot seksuele aktiwiteit : Christelik-etiese studie / Mathys Johannes Bornman." Thesis, North-West University, 2011. http://hdl.handle.net/10394/5547.

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The primary objective of this study was to investigate whether adolescents make use of an ethical decision–making framework when they make choices in relation to sexual activities and the elements that make up this ethical decision–making framework. The adolescent stage of development is characterized by physical and cognitive changes, of which the development of sexual characteristics and morality are only parts. Both these developments are discussed at length within the context of adolescent sexual activity, and cognitive and moral development. Different influences on the morality of adolesc
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35

Bossaller, Jenny S. "A phenomenological study of a of new adult reader's participation in a community reading program." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/5547.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2008.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on June 2, 2009). Vita. Includes bibliographical references.
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Rusli, Yetti. "The Indonesian plywood industry, environmental conservation policy, and the long-run market adjustment /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/5547.

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37

Perkins, Richard Mark. "PIV Measurements of Turbulent Flow in a Rectangular Channel over Superhydrophobic Surfaces with Riblets." BYU ScholarsArchive, 2014. https://scholarsarchive.byu.edu/etd/5547.

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In this thesis I investigate characteristics of turbulent flow in a channel where one of the walls has riblets, superhydrophobic microribs, or a hybrid surface with traditional riblets built on a superhydrophobic microrib surface. PIV measurements are used to find the velocity profile, the turbulent statistics, and shear stress profile in the rectangular channel with one wall having a structured test surface. Both riblets and superhydrophobic surfaces can each provide a reduction in the wall shear stress in a turbulent channel flow. Characterizing the features of the flow using particle image
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Camargo, Fernanda Ferreira de. "Efeito do plasma rico em plaquetas e da fibrina rica em plaquetas na cicatrização de feridas cutâneas em ratos." Pontifícia Universidade Católica do Rio Grande do Sul, 2013. http://hdl.handle.net/10923/5547.

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Made available in DSpace on 2013-11-12T11:38:40Z (GMT). No. of bitstreams: 1 000452038-Texto+Completo-0.pdf: 5927941 bytes, checksum: d7c697db12eaa2a93c2f82acbfe45c20 (MD5) Previous issue date: 2013<br>Objective: To evaluate the effect of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) on cutaneous wound healing in rats by comparing treated and control wounds. Material and Methods: Forty-eight Wistar rats were used in the study. Two wounds with 1-cm diameter, of total skin thickness, were excised from the back of the animals and treated with either PRP or PRF and saline (paired mod
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Aquino, Valério Rodrigues. "Distribuição de espécies, perfil de suscetibilidades ao fluconazol e fatores de risco para candidemia no Hospital de Clínicas de Porto Alegre." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/5547.

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Santos, Marcio Cesar dos. "Identificar as principais fontes de incerteza na cadeia de suprimentos para exportação de açúcar e seu impacto no desempenho: estudo de múltiplos casos." reponame:Repositório Institucional do FGV, 2009. http://hdl.handle.net/10438/5547.

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Made available in DSpace on 2010-04-20T20:20:00Z (GMT). No. of bitstreams: 1 68070200642.pdf: 1534084 bytes, checksum: 41dee5b96ccc619065221be8b71e25d4 (MD5) Previous issue date: 2009-12-03T00:00:00Z<br>As empresas estão cada vez mais conscientes de que a competição se dá entre cadeias de suprimentos e que a integração e o gerenciamento bem sucedidos dos processos de negócio entre os membros da cadeia de suprimentos determinará o sucesso final das empresas (SIMON, 2005). Segundo dados da UNICA (2009) o Brasil lidera o mercado mundial de açúcar com 38% do mesmo na safra 2008/09, exportando
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41

Noche-Dowdy, Liotta Desiree. "Multi-Isotope Analysis to Reconstruct Dietary and Migration Patterns of an Avar Population from Sajópetri, Hungary, AD 568-895." Scholar Commons, 2015. https://scholarcommons.usf.edu/etd/5547.

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The Avar were nomadic people from Central Asia who migrated into the Carpathian Basin in Central-Eastern Europe during the mid to late Migration Period (AD 568 - 895). Archaeological evaluation of grave goods and documentation of mortuary practices have been the primary means of understanding the Avar. However, this approach has largely neglected skeletal and biochemical analysis, in particular as these approaches relate to the biological variation, ancestry, and dietary patterns of the Avar. There remains debate as to whether disparities existed among the socially stratified Avar population o
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42

Lee, John Hung. "Altered mTOR signaling in Huntington's Disease." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/5547.

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Huntington's Disease (HD) is caused by a polyglutamine tract expansion in huntingtin (HTT). Despite HTTs ubiquitous expression, there is selective vulnerability in a specific brain region known as the striatum, the cause of which is poorly understood. Here, we provide evidence that impaired striatal mTORC1 activity underlies varied metabolic and degenerative phenotypes in striatal tissues from HD mouse models and patients, and show that further mTORC1 impairment in mouse models, achieved through the knockdown of Rhes, a striatum-enriched mTORC1 activator, exacerbates disease phenotypes. In con
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Ruiz, Brian A. "Utilizing Voltage-gated Calcium Channels to Assess the Activity of Cathinone Derivatives at Human Monoamine Transporters." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5547.

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Cathinones are psychostimulant compounds heavily implicated as drugs of abuse. They exert their physiological actions at the monoamine transporters, which are responsible for maintaining synaptic neurotransmitter homeostasis. Monoamine transporters produce currents during transport and have been shown to depolarize cell membranes and activate voltage-gated calcium channels in mammalian expression systems. This phenomenon is harnessed in an assay which measures these induced calcium transients, allowing for quantification of pharmacodynamic effects of compounds at monoamine transporters. It is
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Cort-Blackson, Maureen. "The Effects of Sleep Deprivation on Online University Students' Performance." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5547.

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Sleep deprivation affects the academic performance of online university students, and students who have family responsibilities and a full-time job have a higher prevalence of sleep deprivation. This phenomenological study examined the lived experiences of online university students regarding sleep patterns, sleep deprivation, and the impact on their academic performance. The theoretical foundation for this study was based on the opponent processing model that explains the 2 fundamental processes necessary for individuals to function at their optimum ability: the sleep-wake homeostatic process
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45

Aphane, Abraham Kalaudia. "Effect of thermomechanical processing on the surface roughening of AA6061." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/5547.

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Includes bibliographical references.<br>Surface roughening is an undesirable feature in materials. This work investigates the cause of surface roughening in four plates of AA6061 with different thicknesses (Le. 6 mm, 9 mm and two 12 mm). Production of these plates requires thermomechanical processing of the cast slab via a two stage process, namely the initial rolling stage on a hot roughing mill (HRM) and final rolling on the hot finishing mill (HFM). After rolling. the plates are levelled by a tensile stretching process and it is during this process that surface roughening of the plates can
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46

Tendwa, Maureen Bilinga. "Investigating effects of aqueous root extract of Mondia whitei on sperm functionality." University of the Western Cape, 2016. http://hdl.handle.net/11394/5547.

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Magister Scientiae (Medical Bioscience) - MSc(MBS)<br>Introduction: Mondia whitei commonly known as "White Ginger" is a highly acclaimed medicinal plant that is extensively used across Africa. M. whitei is used as treatment for sexual dysfunction and is considered to be an aphrodisiac by traditional medicine practitioners. Yet, scientific evidence to support these claims are minimal and those that are published possess ambiguity. To date, only one study reporting the in vitro effect of the aqueous rhizome extract of M. whitei on human sperm motility is available. Therefore, the aim of the stud
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47

Graf, Gary C. "Carbonate mudmound complexes of the Upper Silurian Douro and Barlow Inlet Formations at Gascoyne Inlet, Devon Island, Arctic Canada." Thesis, University of Ottawa (Canada), 1988. http://hdl.handle.net/10393/5547.

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Sirard, Stéphanie. "Analyse génotypique et phénotypique d'isolats cliniques de Clostridium difficile et comparaison en fonction de la sévérité des symptômes." Mémoire, Université de Sherbrooke, 2011. http://hdl.handle.net/11143/5547.

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Clostridium difficile est la principale cause de diarrhées nosocomiales liées à la prise d'antibiotiques. La souche hypervirulente NAP1/027 est apparue récemment et a causé de nombreuses épidémies en Amérique du Nord et en Europe. On considère généralement que cette souche produit plus de toxines, sporule davantage, provoque des infections plus sévères menant à des complications et est souvent associée aux cas de récurrence. Toutefois, des études récentes ont montré des données contradictoires à ce sujet. L'objectif de mes travaux de recherche est donc de déterminer si l'issue clinique des inf
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49

Luo, Honglin. "Experimental DNA vaccine against filariasis." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5547.

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Filarial infections are major causes of morbidity in the tropics and sub-tropics, afflicting over 150 million people in about 80 countries, causing debilitating symptoms such as elephantiasis (lymphatic filariasis), dermatitis and blindness (onchocerciasis or river blindness). Current control of lymphatic filariais relies on mass drug treatment with diethylcarbamazine（DEC) and albendazole while ivermectin is used against onchocerciasis. Repeat treatment is frequently required and this highlights the possibility of development of drug resistance. In addition, risk of adverse reactions following
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Cunha, Sofia Isabel Rasgado Rodrigues Monteiro da. "Planear e inovar : contributo para o planeamento de recursos com base nas necessidades auto-avaliadas pela população com 65 e mais anos." Master's thesis, Escola Nacional de Saúde Pública. Universidade Nova de Lisboa, 2010. http://hdl.handle.net/10362/5547.

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RESUMO - Enquadramento: O envelhecimento da população ocorre em todas as sociedades desenvolvidas, resultando num aumento da prevalência da dependência funcional, associado recorrentemente à presença de doenças crónicas. Estes novos padrões demográficos, epidemiológicos, implicando populações vulneráveis com necessidades específicas, resultam em desafios incontestáveis. Como resposta a este novo paradigma, em 2006, Portugal implementa a Rede Nacional de Cuidados Continuados Integrados (RNCCI). Finalidade/objectivos: Caracterização da população com base no perfil das necessidades auto-refe
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