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1

Uno, Yuji, Naoko Akiyama, Sayaka Yuzawa, Masahiro Kitada, and Hidehiro Takei. "The value and practical utility of intraoperative touch imprint cytology of sentinel lymph node(s) in patients with breast cancer: A retrospective cytology-histology correlation study." Cytojournal 17 (May 12, 2020): 11. http://dx.doi.org/10.25259/cytojournal_80_2019.

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Objective: Intraoperative evaluation of sentinel lymph nodes (SLNs) for patients with breast cancer is widely performed with frozen section (FS), cytology, or a combination of both. Touch imprint cytology (TIC) reportedly has an equivalent sensitivity to FS. We studied its diagnostic utility to detect SLN metastases. Materials and Methods: Cases of 367 patients with breast cancer who underwent intraoperative valuation of SLNs (507 LNs) were evaluated. All FS and corresponding TIC slides of SLNs of each case were reviewed microscopically for the presence of metastases of any size. If present, t
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2

Galvis Rojas, Giovanni, Magnus Husberg, and Lars-Ake Levin. "Cost-effectiveness analysis of population-based screening for 6-gene panel testing for hereditary breast and ovarian cancer." Journal of Clinical Oncology 43, no. 16_suppl (2025): 10541. https://doi.org/10.1200/jco.2025.43.16_suppl.10541.

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10541 Background: Genetic testing for hereditary breast and ovarian cancer (HBOC) has relied on clinical and family history criteria. This approach, has been shown to overlook a significant number of mutation carriers who could benefit from preventative measures. Increasing evidence supports genetic testing in an unselected population, which facilitates the identification of more carriers and allows for the implementation of risk reduction strategies. The aim of this study is to evaluate the cost-effectiveness of utilising an expanded gene-panel in an unselected female population. Methods: A M
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Sasaki, Koji, Ildefonso Ismael Rodriguez-Rivera, Hagop M. Kantarjian, et al. "Correlation of Lymphocyte Count with Treatment Response to Tyrosine Kinase Inhibitors in Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase." Blood 124, no. 21 (2014): 4538. http://dx.doi.org/10.1182/blood.v124.21.4538.4538.

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Abstract Background: Total lymphocyte count (TLC) has been shown to correlate with outcomes in patients (pts) with acute leukemia. The clinical correlation to TLC in pts with chronic myeloid leukemia in chronic phase (CML-CP) who were treated with a tyrosine-kinase inhibitor (TKI) is unclear. Methods: Lymphocyte data in pts with newly diagnosed CML-CP who were enrolled in consecutive or parallel clinical trials with front-line imatinib (IM), nilotinib (Nilo), or dasatinib (Dasa) were collected at the time of diagnosis, and 3 and 6 months (M) after the start of TKI. Relative lymphocytrosis (RLC
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4

Miranda, Vanessa Costa, Angelo Bezerra de Sousa Fede, Carlos Henrique Dos Anjos, et al. "Neoadjuvant chemotherapy with six cycles of carboplatin and paclitaxel in advanced ovarian cancer patients not candidates for optimal primary surgery: Safety and effectivenes." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5540. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5540.

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5540 Background: Primary debulking surgery (PDS) has been considered the standard of treatment in advanced ovarian cancer, while neoadjuvant chemotherapy, three cycles followed by interval debulking (ID) surgery, is a valid treatment alternative for patients with non-resectable disease. This study aimed to show the efficacy and safety of six cycles of neoadjuvant chemotherapy (N-CT) followed by cytoreduction, a single institution experience. Methods: Aretrospective analysis was performed of all patients (pts) with advanced ovarian cancer treated with platinum based N-CT, between January/2004 a
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5

Tillett, W., V. Navarro-Compán, N. Booth, et al. "AB0548 EFFECTIVENESS OF IXEKIZUMAB IN PATIENTS WITH PSORIATIC ARTHRITIS: RESULTS FROM A REAL-WORLD EUROPEAN SURVEY." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1307–8. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2001.

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Background:Limited real world (RW) data are available for IL-17A blocker ixekizumab (Ixe), approved for psoriatic arthritis (PsA) in EU Feb 2018.Objectives:Describe RW outcomes for PsA patients (pts) receiving Ixe.Methods:Cross-sectional, observational study of PsA pts treated with Ixe in the 2020 Adelphi PsA Plus Program (FR, DE, ES & UK). Rheumatologists recruited the first 6 consecutive consulting Ixe pts and provided demographics, PsA manifestations, clinical measures (66 swollen joint count (SJC), 68 tender joint count (TJC), psoriasis area and severity index [PASI], body surface area
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Mamyrko, Yu V., A. S. Bushnev, D. A. Kuriliva, and I. А. Kotlyarova. "Features of the formation of highly productive crops of a new sunflower hybrid Fogor." Oil Crops 1, no. 197 (2024): 76–82. http://dx.doi.org/10.25230/2412-608x-2024-1-197-76-82.

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Influence of seed sowing rates (40, 60 as control and 80 thousand seeds/ha) on productivity of sunflower hybrid Fogor was studied on leached black soils of the Western Ciscaucasia (Korenovsk district, Kranodar region) in 2022–2023. It is established the highest seed (3.62 t/hа) and oil (1.46 t/hа) yields are reached at the seed-sowing rate of 80 thousand seeds/ha under sufficient moisture supply. Under weather conditions of 2022–2023, the less prevalence of bacteriosis (by 2 and 13%) and rust (by 6 and 8%, respectively) in the crops were observed. In 2023, population of fungal micoflore in rhi
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7

Nguyễn, Thị Thu Hằng, Thụy Mai Thy Đặng, Thị Mỹ Duyên Trần, Bảo Trung Nguyễn, Tài Tảo Châu та Thị Tuyết Hoa Trần. "Khảo sát thành phần ký sinh trùng trên cua biển (Scylla paramamosain) nuôi quảng canh ở tỉnh Cà Mau". CTU Journal of Science 60, № 6 (2024): 190–202. https://doi.org/10.22144/ctujos.2024.484.

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Nghiên cứu được tiến hành nhằm tìm hiểu mầm bệnh ký sinh trùng trên cua biển nuôi quảng canh ở tỉnh Cà Mau. Kết quả đã xác định được 7 giống ký sinh trùng trong mang, máu, gan tụy và khoang cơ thể cua biển: Acineta, Epistylis, Hematodinium, Octolasmic, trùng lông Peniculida, giun tròn Nematoda và Portunion. Các giống ký sinh trùng có chỉ số đa dạng Shannon: 0,8. Giống Portunion ký sinh trong khoang cơ thể của cua biển làm cho cơ bị tiêu biến và làm thay đổi đặc điểm sinh dục thứ cấp. Kết quả kiểm tra 83 mẫu có 82 mẫu bị nhiễm ký sinh trùng. Ấu trùng Portunion có tỷ lệ nhiễm cao nhất (86,7%) tr
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8

Kurta, Allen, and Steven M. Smith. "Hibernating Bats and Abandoned Mines in the Upper Peninsula of Michigan." Northeastern Naturalist 21, no. 4 (2014): 587–605. https://doi.org/10.5281/zenodo.13448704.

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(Uploaded by Plazi for the Bat Literature Project) Prior to arrival of white-nose syndrome, we found bats hibernating in 82 of 119 abandoned mines in northern Michigan. Unoccupied sites typically were short (19 ± 17 m 6' DQG RU H[SHULHQFHG FKLPQH\ HIIHFW DLUÀRZ ZKLFK OHG WR WHPSHUDWXUHV QHDU RU EHORZ freezing (-0.8 ± 2.9 ºC). Overall, occupied sites were more structurally complex, longer (307 ± 865 m), and warmer (5.7 ± 3.0 ºC) than unoccupied mines. Number of bats varied from 1 to > 55,000, although the median was 115. 3HULP\RWLV VXEÀDYXV (Eastern Pipistrelle) and Eptesicus fuscus (Big Bro
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Kurta, Allen, and Steven M. Smith. "Hibernating Bats and Abandoned Mines in the Upper Peninsula of Michigan." Northeastern Naturalist 21, no. 4 (2014): 587–605. https://doi.org/10.5281/zenodo.13448704.

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(Uploaded by Plazi for the Bat Literature Project) Prior to arrival of white-nose syndrome, we found bats hibernating in 82 of 119 abandoned mines in northern Michigan. Unoccupied sites typically were short (19 ± 17 m 6' DQG RU H[SHULHQFHG FKLPQH\ HIIHFW DLUÀRZ ZKLFK OHG WR WHPSHUDWXUHV QHDU RU EHORZ freezing (-0.8 ± 2.9 ºC). Overall, occupied sites were more structurally complex, longer (307 ± 865 m), and warmer (5.7 ± 3.0 ºC) than unoccupied mines. Number of bats varied from 1 to > 55,000, although the median was 115. 3HULP\RWLV VXEÀDYXV (Eastern Pipistrelle) and Eptesicus fuscus (Big Bro
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10

Kurta, Allen, and Steven M. Smith. "Hibernating Bats and Abandoned Mines in the Upper Peninsula of Michigan." Northeastern Naturalist 21, no. 4 (2014): 587–605. https://doi.org/10.5281/zenodo.13448704.

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(Uploaded by Plazi for the Bat Literature Project) Prior to arrival of white-nose syndrome, we found bats hibernating in 82 of 119 abandoned mines in northern Michigan. Unoccupied sites typically were short (19 ± 17 m 6' DQG RU H[SHULHQFHG FKLPQH\ HIIHFW DLUÀRZ ZKLFK OHG WR WHPSHUDWXUHV QHDU RU EHORZ freezing (-0.8 ± 2.9 ºC). Overall, occupied sites were more structurally complex, longer (307 ± 865 m), and warmer (5.7 ± 3.0 ºC) than unoccupied mines. Number of bats varied from 1 to > 55,000, although the median was 115. 3HULP\RWLV VXEÀDYXV (Eastern Pipistrelle) and Eptesicus fuscus (Big Bro
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11

Kurta, Allen, and Steven M. Smith. "Hibernating Bats and Abandoned Mines in the Upper Peninsula of Michigan." Northeastern Naturalist 21, no. 4 (2014): 587–605. https://doi.org/10.5281/zenodo.13448704.

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(Uploaded by Plazi for the Bat Literature Project) Prior to arrival of white-nose syndrome, we found bats hibernating in 82 of 119 abandoned mines in northern Michigan. Unoccupied sites typically were short (19 ± 17 m 6' DQG RU H[SHULHQFHG FKLPQH\ HIIHFW DLUÀRZ ZKLFK OHG WR WHPSHUDWXUHV QHDU RU EHORZ freezing (-0.8 ± 2.9 ºC). Overall, occupied sites were more structurally complex, longer (307 ± 865 m), and warmer (5.7 ± 3.0 ºC) than unoccupied mines. Number of bats varied from 1 to > 55,000, although the median was 115. 3HULP\RWLV VXEÀDYXV (Eastern Pipistrelle) and Eptesicus fuscus (Big Bro
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12

Kurta, Allen, and Steven M. Smith. "Hibernating Bats and Abandoned Mines in the Upper Peninsula of Michigan." Northeastern Naturalist 21, no. 4 (2014): 587–605. https://doi.org/10.5281/zenodo.13448704.

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(Uploaded by Plazi for the Bat Literature Project) Prior to arrival of white-nose syndrome, we found bats hibernating in 82 of 119 abandoned mines in northern Michigan. Unoccupied sites typically were short (19 ± 17 m 6' DQG RU H[SHULHQFHG FKLPQH\ HIIHFW DLUÀRZ ZKLFK OHG WR WHPSHUDWXUHV QHDU RU EHORZ freezing (-0.8 ± 2.9 ºC). Overall, occupied sites were more structurally complex, longer (307 ± 865 m), and warmer (5.7 ± 3.0 ºC) than unoccupied mines. Number of bats varied from 1 to > 55,000, although the median was 115. 3HULP\RWLV VXEÀDYXV (Eastern Pipistrelle) and Eptesicus fuscus (Big Bro
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13

Lebedeva, N. B., P. G. Parfenov, A. P. Egle, et al. "External validation of a multivariate model for predicting the risk of death in patients with chronic heart failure and an implantable cardioverter – defibrillator." Bulletin of Siberian Medicine 23, no. 2 (2024): 74–82. http://dx.doi.org/10.20538/1682-0363-2024-2-74-82.

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Aim. To perform external validation of a multivariate model for predicting the risk of death in patients with an implantable cardioverter – defibrillator (ICD) in an independent sample. Materials and methods. The group for model development included 260 patients from the Implantable Cardioverter – Defibrillator Patient Registry who had an ICD implanted between 2015 and 2019. External validation of the model was carried out in an independent, prospective, observational cohort study of patients from the same registry, in whom an ICD was implanted between 2020 and 2021, a total of 94 patients, me
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14

Omelchenko, T., O. Burianov, A. Liabakh, E. Levitskyi, and O. Turchin. "AB1226 AUTOLOGOUS MOSAIC OSTEOCHONDROPLASTY IN THE TREATMENT OF TALAR OSTEOCHONDRAL DEFECTS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1725.3–1726. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4901.

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BackgroundOsteochondral defects of the talus (ODT) is a relatively rare, mostly traumatic pathology, in 6.5 % of cases complicate the course of inversion and eversion injuries of the foot and ankle [1].ObjectivesTo conduct a clinical analysis of the effectiveness of autologous mosaic osteochondroplasty in the treatment of patients with osteochondral defects of the talus on the basis of determining the dynamics of pain and restoring the amplitude of ankle movements.MethodsThe study included 34 patients with post-traumatic osteochondral defects of the talus (27 men, 7 women, mean age 24.8 ± 2.1
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15

Manolakis, Al, C. Ionescu, M. Cambrea, P. Bordei, and D. Iliescu. "Relations between the tracheal and pulmonary trunk bifurcations." ARS Medica Tomitana 20, no. 2 (2014): 110–14. http://dx.doi.org/10.2478/arsm-2014-0020.

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Abstract The bifurcation of the pulmonary trunk and trachea were followed on 52 cases being appreciated on the dissection and corrosion pieces and CT examinations, the arterial bifurcation being made under an very variable angle, its value ranging from 30-1080. In 82% of cases the tracheal bifurcation was done under an acute angle, with lower value than the arterial bifurcation angle. In 41 cases (78.85% of cases) the pulmonary trunk bifurcation is done under the bifurcation of the trachea, at a distance of between 0,4 - 2,8 cm, and in 8 patients (15.38% of the cases) the two bifurcations was
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16

MacIntyre, C. Raina, Marianne Empson, Claire Boardman, Doungkamol Sindhusake, Julie Lokan, and Graham V. Brown. "Risk Factors for Colonization With Vancomycin-Resistant Enterococci in a Melbourne Hospital." Infection Control & Hospital Epidemiology 22, no. 10 (2001): 624–29. http://dx.doi.org/10.1086/501833.

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AbstractObjective:To determine risk factors for colonization with vancomycin-resistant enterococci (VRE) in a hospital outbreak.Design:Outbreak investigation and case-control study.Setting:A referral teaching hospital in Melbourne, Australia.Participants:Cases were inpatients colonized (with or without clinical disease) with VRE between July 26 and November 28, 1998; controls were hospitalized patients without VRE.Methods:Five cases of VRE were identified between July 26 and November 8, 1998, by growth of VRE from various sites. Active case finding by cultures of rectal swabs from patients sur
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Kamal, Mustafa, Abdur Rahim, Muhammad Tanvir Muhith, Shaoun Barua, Md Abdullah Yusuf, and Hafez Muhammad Nazmul Ahsan. "Clinical Profiles of Chikungunya Fever Patients Attending at OPD of a Teaching Hospital in Dhaka City." Journal of National Institute of Neurosciences Bangladesh 5, no. 2 (2019): 148–51. http://dx.doi.org/10.3329/jninb.v5i2.43020.

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Background: Chikungunya virus was introduced into the Dhaka city of Bangladesh and triggered a massive outbreak which affected millions of lives and forced upon significant damages in socioeconomic factors.
 Objectives: This community based descriptive study was conducted in selected area of Dhaka city to see the clinical profiles of chikungunya patients in Dhaka city.
 Methodology: This prospective observational study was carried out in the Department of Medicine OPD at Shaheed Suhrawardy Medical College & Hospital (ShSMC), Dhaka, Bangladesh. This cross-sectional study was condu
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Özdem, Tayfun, Furkan Burak Akyol, Cahit Murat Balaman, et al. "[MSB-33] Postoperative Early- to Mid-Term Results of the Ozaki Procedure Applied to Aortic Valve Pathologies." Turkish Journal of Thoracic and Cardiovascular Surgery 32, no. 4 (2024): 57. https://doi.org/10.5606/tgkdc.dergisi.2024.msb-33.

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Objective: This study aimed to evaluate our early- to mid-term results with the aortic valve neocuspidization technique (Ozaki procedure) in aortic valve pathologies. METHOD: This study retrospectively examined the data of 243 patients (172 males, 71 females; mean age: 53.11±18.3 years; range, 17 to 82 years) who underwent the Ozaki procedure between February 2019 and August 2024. Results: The primary pathology was aortic insufficiency in 52 (21.3%) patients and aortic stenosis in 201 (82.7%) patients. The aortic valve morphology was trileaflet in 196 (80.6%) patients, bileaflet in 44 (18.1%)
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Özdem, Tayfun, Furkan Burak Akyol, Cahit Murat Balaman, et al. "[MSB-33] Postoperative Early- to Mid-Term Results of the Ozaki Procedure Applied to Aortic Valve Pathologies." Cardiovascular Surgery and Interventions 11, no. 100 (2024): 38. https://doi.org/10.5606/e-cvsi.2024.msb-33.

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Objective: This study aimed to evaluate our early- to mid-term results with the aortic valve neocuspidization technique (Ozaki procedure) in aortic valve pathologies. METHOD: This study retrospectively examined the data of 243 patients (172 males, 71 females; mean age: 53.11±18.3 years; range, 17 to 82 years) who underwent the Ozaki procedure between February 2019 and August 2024. Results: The primary pathology was aortic insufficiency in 52 (21.3%) patients and aortic stenosis in 201 (82.7%) patients. The aortic valve morphology was trileaflet in 196 (80.6%) patients, bileaflet in 44 (18.1%)
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20

O.О. Сікорин та Н.В. Скрипник. "Порушення вуглеводного та ліпідного обміну у пацієнтів із гіпотиреозом". Прикарпатський вісник наукового товариства імені Шевченка ПУЛЬС, № 22 (75) (26 грудня 2024): 82–94. https://doi.org/10.21802/2304-7437-2024-22(75)-82-94.

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Резюме. У статті представлені результати обстеження 80 пацієнтів із гіпотиреозом, які проходили амбулаторне та стаціонарне лікування в ендокринологічному відділенні КНП «Івано-Франківська обласна клінічна лікарня Івано-Франківської обласної ради» протягом 2023–2024 років. Основна мета дослідження – вивчення порушень вуглеводного обміну, інсулінорезистентності (ІР), гормонального профілю, ліпідного обміну у пацієнтів із гіпотиреозом. Гіпотиреоз супроводжується комплексом метаболічних порушень, зокрема, інсулінорезистентністю (ІР), дисліпідемією, абдомінальним ожирінням і порушенням функції печі
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Cintean, Raffael, Alexander Eickhoff, Carlos Pankratz, Beatrice Strauss, Florian Gebhard, and Konrad Schütze. "Radial vs. Dorsal Approach for Elastic Stable Internal Nailing in Pediatric Radius Fractures—A 10 Year Review." Journal of Clinical Medicine 11, no. 15 (2022): 4478. http://dx.doi.org/10.3390/jcm11154478.

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Background: Forearm fractures are one of the most common fractures in children. Over the last years, a tendency towards surgical treatment was seen, especially closed reduction and internal fixation with elastic stable internal nailing (ESIN). Despite an overall low complication rate being described, a risk of intraoperative complications remains. Material and Methods: A total of 237 patients (mean age 8.3 ± 3.4 (1–16) years) with forearm or radius fractures treated with ESIN between 2010 and 2020 were included in the study. The retrospective review of 245 focused on fracture pattern, pre- and
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22

Alsaadi, Khalid, Khalid Algaali, Eman Elsayed Abd-Ellatif, et al. "Anxiety and Depression Symptoms among Quarantined Adults and Related Risk Factors During COVID-19 Pandemic: A Cross-Sectional Study." Dr. Sulaiman Al Habib Medical Journal 7, no. 1 (2025): 8–15. https://doi.org/10.4103/dshmj.dshmj_88_24.

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Abstract Background: Quarantine, characterized as isolation, may either initiate or intensify mental health disorders such as anxiety or depression. Researchers have assessed the risk variables related to these diseases during the coronavirus (COVID-19) pandemic. We assessed the prevalence of anxiety and depression, in addition to identifying related risk variables, among confined Omani adult citizens in northern Oman. Methods: We performed cross-sectional research among citizens of ages 18 and higher who were quarantined for a minimum of 10 days owing to travel or contact with infected person
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Dimian, Caroline O., Michael J. O'Doherty, David Asboe, Christopher J. Page, Kate Entwisle, and James S. Bingham. "Radioactively labelled diethylene triamine penta acetate lung scan in Pneum ocystis carinii pneumonia and asymptomatic HIV-positive patients." International Journal of STD & AIDS 8, no. 8 (1997): 482–88. http://dx.doi.org/10.1258/0956462971920622.

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The objective of this study is to establish normal ranges for the assessment of lung permeability, using 99mTc DTPA (diethylene triamine penta acetate) aerosol by measuring the half-time of transfer from the lung in asymptomatic HIV-positive patients. Also to audit the use of the test in the clinical management of outpatients with symptoms suggestive of Pneumocystis carinii pneumonia (PCP). A retrospective analysis of data from outpatients' notes for the audit of symptomatic patients, and prospective acquisition of 'normal' data for HIVpositive asymptomatic patients who were non-smokers and sm
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Vuillard, Constance, Fadia Dib, Jallal Achamlal, et al. "Longer symptom onset to aspiration time predicts success of needle aspiration in primary spontaneous pneumothorax." Thorax 74, no. 8 (2019): 780–86. http://dx.doi.org/10.1136/thoraxjnl-2019-213168.

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BackgroundNeedle aspiration (NA) is recommended as first-line treatment of primary spontaneous pneumothorax (PSP). We aimed to assess NA success and the effect of a longer symptom onset to NA time.MethodsA discovery phase was retrospectively conducted in the intensive care unit of Louis Mourier Hospital (January 2000 to December 2011) followed by a prospective validation cohort (January 2012 to August 2015). The primary outcome was immediate NA success defined by the absence of need for chest tube insertion within 24 hours of the procedure.ResultsIn the discovery phase, 130 patients were admit
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Lohankova, L. A., Yu V. Kotovskaya, A. S. Milto, and Zh D. Kobalava. "The structural and functional features of the microcirculatory bed in patients with arterial hypertension and type 2 diabetes mellitus." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 11, no. 3 (2005): 177–80. http://dx.doi.org/10.18705/1607-419x-2005-11-3-177-180.

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The structural and functional features of the microcirculatory heel (MCB) were studied in patients with arterial hypertension (AH) in relation to the presence or absence of type 1 diabetes mellitus (DM). Two hundred and twelve patients were examined. These included 110 patients with grades 1 and 2 arterial hypertension (AH) and type 2 DM, 82 patients with AH without type 2 DM, and 20 apparently healthy individuals. Laser Doppler flowmetry (LDF) was used to estimate basal blood flow, the loading test parameters characterizing the structural and functional status of MCB, and the incidence of hem
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Ohji, Madoka, Hiroya Harino, and William John Langston. "Differences in bioaccumulation and transfer ability between tributyltin and triphenyltin from parental female to offspring in viviparous surfperch Ditrema temmincki." Journal of the Marine Biological Association of the United Kingdom 98, no. 8 (2017): 2113–20. http://dx.doi.org/10.1017/s0025315417001436.

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To examine the risk of transgenerational transfer of organotin compounds (OTs) in fish, tributyltin (TBT) and triphenyltin (TPT) compounds and their breakdown products were determined in both parental females and offspring of viviparous surfperch Ditrema temmincki collected from Japanese coastal waters. TBT concentrations (Mean ± SD) in the offspring (34 ± 5.7 ng Sn g−1 wet wt) were significantly higher (10–17 times) than in the parental females (2.8 ± 1.0 ng Sn g−1 wet wt). In the offspring, TBT was the predominant butyltin compound (82 ± 1.6% ∑BTs = TBT + DBT + MBT), and represented a greate
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Filippov, E. G., A. A. Dontsova, D. P. Dontsov, E. S. Doroshenko, R. N. Bragin, and I. M. Zasypkina. "Spring barley variety ‘Azimut’." Grain Economy of Russia, no. 5 (November 16, 2022): 91–97. http://dx.doi.org/10.31367/2079-8725-2022-82-5-91-97.

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Improvement of feed grain production is an important link in Russia’s food security. Considerable opportunities for solving this problem lie in the cultivation of new domestic varieties of barley. Breeding work in this direction has been carried out for a long time in the Don area by the FSBSI “ARC “Donskoy” (Department of winter and spring barley breeding and seed production). The purpose of the study was to breed a new spring barley variety for regions with high signs of aridy, which has fairly large productivity and its stability in different years. The result of the breeding program 0706-2
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Li, Yahan, Xue Sun, Xin Wang, and Xiaosheng Fang. "Combination of NCCN Risk Stratification System and Pre-Transplant Minimal Residual Disease Levels for the Prognosis of Acute Myeloid Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation." Blood 138, Supplement 1 (2021): 3434. http://dx.doi.org/10.1182/blood-2021-149479.

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Abstract Background Numerous studies have confirmed that National Comprehensive Cancer Network (NCCN) risk stratification or pre-transplant minimal residual disease (MRD) levels can predict the risk of recurrence and survival after transplantation. But it is unclear whether combining these two parameters can more accurately predict prognosis. Methods We retrospectively analyzed 85 patients with acute myeloid leukemia (AML) who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) and constructed a new risk stratification tool combining NCCN risk stratification and pre-MRD le
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Bazylev, V. V., R. M. Babukov, F. L. Bartosh, and A. V. Gorshkova. "Comparison of the hemodynamic parameters of transaortic blood flow in patients with aortic stenosis depending on the bicuspid or tricuspid valve structure." Medical Visualization 24, no. 4 (2020): 74–80. http://dx.doi.org/10.24835/1607-0763-2020-4-74-80.

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Purpose: comparison of hemodynamic parameters of transaortic blood flow in patients with aortic stenosis depending on the bivalve or tricuspid structure of the aortic valve.Materials and methods. A study of 180 patients with isolated aortic valve stenosis (AC) with two – and threeleaf structure was conducted. Patients were ranked into 3 comparison subgroups by the area of the effective AC opening from 4 to 1.5 cm2; 1.5 to 1 cm2 and less than 1 cm2. An echocardiographic study was performed with the calculation of all the necessary parameters for the study.Results. The comparison subgroups were
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Szewczyk, Adam, Janina Kaniuczak, Edmund Hajduk, and Renata Knap. "Physical and chemical properties of selected soils from the surroundings of the Magura National Park (southern Poland) / Właściwości fizykochemiczne i chemiczne wybranych gleb z otoczenia Magurskiego Parku Narodowego." Soil Science Annual 66, no. 1 (2015): 36–44. http://dx.doi.org/10.1515/ssa-2015-0017.

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Abstract The aim of the study was to investigate the basic physicochemical and chemical properties of six soil profiles located in the surrounding of the Magura National Park (S Poland). The type of agricultural use and terrain relief were the main criteria for choosing the soil profiles. The research identified the following types or sub-types of soils: Eutric Gleysols, Dystric Cambisols, Eutric Cambisols, Gleyic Luvisols. The analyzed soils were characterized by particle size distribution of a silty clay or silt. They were usually strongly acidified as evidenced by low pH (in 1M KCl, values
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Rose, P. G., J. A. Blessing, A. R. Mayer, and H. D. Homesley. "Prolonged oral etoposide as second-line therapy for platinum-resistant and platinum-sensitive ovarian carcinoma: a Gynecologic Oncology Group study." Journal of Clinical Oncology 16, no. 2 (1998): 405–10. http://dx.doi.org/10.1200/jco.1998.16.2.405.

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PURPOSE A phase II trial was conducted to determine the activity of prolonged oral etoposide in platinum-resistant and platinum-sensitive ovarian carcinoma. PATIENTS AND METHODS Platinum-resistant disease was defined as progression on platinum-based chemotherapy or recurrence within 6 months of completing therapy. The starting dose was 50 mg/m2/d (30 mg/m2/d for prior radiotherapy) for 21 days, every 28 days. A dose escalation to a maximum dose of 60 mg/m2/d was prescribed. RESULTS Of 99 patients entered, 97 were assessable for toxicity and 82 were assessable for response. Among 41 platinum-re
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Nadali, G., F. Vinante, A. Ambrosetti, et al. "Serum levels of soluble CD30 are elevated in the majority of untreated patients with Hodgkin's disease and correlate with clinical features and prognosis." Journal of Clinical Oncology 12, no. 4 (1994): 793–97. http://dx.doi.org/10.1200/jco.1994.12.4.793.

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PURPOSE To evaluate the serum levels of the soluble form of the CD30 molecule (sCD30) in patients with Hodgkin's disease (HD) to establish whether there is a correlation with clinical features at presentation and prognosis. PATIENTS AND METHODS The sCD30 serum levels of 117 patients were measured at diagnosis with a commercial sandwich enzyme-linked immunoadsorbent assay (ELISA) test kit, and in 78 of these patients the sCD30 levels were also recorded during the follow-up period. RESULTS sCD30 levels at diagnosis were increased (> 20 U/mL) in a high proportion of patients (87.2%; mean +/- S
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Ho, Kay Woon, Ru San Tan, Keng Yean Wong, Teng Hong Tan, Sriram Shankar, and Ju Le Tan. "Late Complications Following Tetralogy of Fallot Repair: The Need for Long-term Follow-Up." Annals of the Academy of Medicine, Singapore 36, no. 11 (2007): 947–53. http://dx.doi.org/10.47102/annals-acadmedsg.v36n11p947.

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Introduction: We report a series of operated tetralogy of Fallot (TOF) patients focusing on complications and outcomes. Materials and Methods: Data from TOF patients seen at our centre’s adult congenital heart disease clinic was analysed. Results: There were 21 patients: the mean age was 32.2 ± 12.4 years; the age at first operation was 9.0 ± 7.9 years; the mean postoperative follow-up duration was 23.5 ± 12.1 years; and the current New York Heart Association (NYHA) status: I, 82%; II, 4%; III, 14%. Fourteen patients had complete operative notes. All these patients underwent total TOF correcti
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Rhee, Chanu, Tom Chen, Sameer S. Kadri, et al. "Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals." JAMA Network Open 7, no. 6 (2024): e2418923. http://dx.doi.org/10.1001/jamanetworkopen.2024.18923.

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ImportanceLittle is known about the degree to which suspected sepsis drives broad-spectrum antibiotic use in hospitals, what proportion of antibiotic courses are unnecessarily broad in retrospect, and whether these patterns are changing over time.ObjectiveTo describe trends in empiric broad-spectrum antibiotic use for suspected community-onset sepsis.Design, Setting, and ParticipantsThis cross-sectional study used clinical data from adults admitted to 241 US hospitals in the PINC AI Healthcare Database. Eligible participants were aged 18 years or more and were admitted between 2017 and 2021 wi
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Buda, Gabriele, Alessandro Martino, Daniele Campa, et al. "Polymorphisms in Regulators of Xenobiotic Transport and Metabolism Genes NR1I2 and NR1I3 and Multiple Myeloma Risk: A Case-Control Study in the Context of IMMEnSE Consortium." Blood 118, no. 21 (2011): 5014. http://dx.doi.org/10.1182/blood.v118.21.5014.5014.

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Abstract Abstract 5014 Exposure to toxic compounds and pesticides leads to an increased risk to develop Multiple Myeloma (MM). The metabolism and the excretion of xenobiotics are mediated by the enzymes and transporters acting in the detoxifying/elimination process. The nuclear receptors NR1I2 (or PXR) and NR1I3 (or CAR) act as xenosensor activating the detoxifying/elimination process in response to the intracellular levels of xenobiotics. It has been hypothesized that part of the individual variability in drug metabolism efficiency could be due to the genetic variations within these regulator
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Weber, Myriam C., Martin Risch, Sarah L. Thiel, et al. "Characteristics of Three Different Chemiluminescence Assays for Testing for SARS-CoV-2 Antibodies." Disease Markers 2021 (January 6, 2021): 1–13. http://dx.doi.org/10.1155/2021/8810196.

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Several tests based on chemiluminescence immunoassay techniques have become available to test for SARS-CoV-2 antibodies. There is currently insufficient data on serology assay performance beyond 35 days after symptoms onset. We aimed to evaluate SARS-CoV-2 antibody tests on three widely used platforms. A chemiluminescent microparticle immunoassay (CMIA; Abbott Diagnostics, USA), a luminescence immunoassay (LIA; Diasorin, Italy), and an electrochemiluminescence immunoassay (ECLIA; Roche Diagnostics, Switzerland) were investigated. In a multigroup study, sensitivity was assessed in a group of pa
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Seah, Xue Fen Valerie, Yue Ling Rina Ong, Wei Ming Cedric Poh, Shahul Hameed Mohamed Siraj, Kai-Qian Kam, and Koh Cheng Thoon. "137. Impact of Antimicrobial Stewardship Interventions on Post-Elective Caesarean Antibiotic Prophylaxis and Surgical Site Infections." Open Forum Infectious Diseases 8, Supplement_1 (2021): S182. http://dx.doi.org/10.1093/ofid/ofab466.339.

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Abstract Background Antimicrobial stewardship programs (ASP) aim to improve appropriate antimicrobial use. Post-operative antibiotics are generally not necessary, especially those without surgical site infections risk factors (e.g. obesity). Few studies have described the impact of ASP interventions on patient outcomes especially in unique populations such as obstetrics. This study aims to evaluate the impact of ASP interventions on post-elective caesarean (eLSCS) oral antibiotic prophylaxis use and patient outcomes including SSI rates. Methods This pre-post quasi-experimental study was conduc
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Jack, Darby W., Kenneth Ayuurebobi Ae-Ngibise, Carlos F. Gould, et al. "A cluster randomised trial of cookstove interventions to improve infant health in Ghana." BMJ Global Health 6, no. 8 (2021): e005599. http://dx.doi.org/10.1136/bmjgh-2021-005599.

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IntroductionHousehold air pollution from solid fuel combustion for cooking and heating is a leading cause of childhood morbidity and mortality worldwide. We hypothesised that clean cooking interventions delivered during pregnancy would improve child health.MethodsWe conducted a cluster randomised trial in rural Ghana to test whether providing pregnant women liquefied petroleum gas (LPG) cookstoves or improved biomass cookstoves would reduce personal carbon monoxide and fine particulate pollution exposure, increase birth weight and reduce physician-assessed severe pneumonia in the first 12 mont
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Мирсаева, G. Mirsaeva, Камаева, et al. "Effective treatment of obesity in women of reproductive age." Journal of New Medical Technologies. eJournal 9, no. 4 (2015): 0. http://dx.doi.org/10.12737/16777.

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The study included 82 women aged from 18 to 49 years old (mean age 29,7±5,7 years). A clinical examination, the study of body composition by bioimpedance measuring, questioning were carried out. Statistical analysis was performed using the program Microsoft Exel, "Statistica 7,0". Analysis of the diet revealed the excess of the daily energy value of food intake over energy requirements of 650±250 kcal/day in the group of persons with obesity in comparison with healthy. Disorders of balanced daily diet were noted. To improve motivation and compliance in the "School of ov
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Murias, Juan M., Kenneth N. Grise, Mao Jiang, Hana Kowalchuk, C. W. James Melling, and Earl G. Noble. "Acute endurance exercise induces changes in vasorelaxation responses that are vessel-specific." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 304, no. 7 (2013): R574—R580. http://dx.doi.org/10.1152/ajpregu.00508.2012.

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The dynamic adjustment and amplitude of the endothelium-dependent vasorelaxation of the carotid, aorta, iliac, and femoral vessels were measured in response to acute low- (LI) or high-intensity (HI) endurance exercise. Vasorelaxation to 10−4 M ACh was evaluated in 10 control, 10 LI, and 10 HI rats. Two-millimeter sections of carotid, aorta, iliac, and femoral arteries were mounted onto a myography system. Vasorelaxation responses were modeled as a monoexponential function. The overall τ (control, 10.5 ± 6.0 s; LI, 10.4 ± 5.7 s; HI, 11.0 ± 6.9 s) and time-to-steady-state (control, 47.6 ± 24.0 s
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Dr., Hira Shahzad Dr. Salman Falak Dr. Tooba Jalees. "A CROSS-SECTIONAL RESEARCH ON PCI (PERCUTANEOUS CORONARY INTERVENTION, BLEEDING SITE & ASSOCIATED RISK FACTORS IN CONTEXT TO MAJOR & MINOR BLEEDING & BLEEDING DEFINITIONS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 06 (2018): 5892–97. https://doi.org/10.5281/zenodo.1301256.

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Objectives: This research aimed to find out the risk factors and bleeding association in the patients experiencing PCI (Percutaneous Coronary Intervention). Methodology: We included 500 consecutive cases in our cross-sectional research who experienced PCI at Allied Hospital, Faisalabad (October, 2016 to December, 2017). We defined bleeding in per the criteria of “REPLACE – 2”. Results: Male to female proportion in our research was respectively 82 and 418 with respective percentage of 16.4% & 83.6% with a dominance of male over female. The factor of mean age was observed a
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Gomes, Tiago Halyson de Oliveira, Welleson Feitosa Gazel, Emanuela Ferreira Goulart, Jennifer Lee Gonçalves, Gabriel Vargas Maia Chaves, and Lígia Luana Freire da Silva. "ÓBITOS DEVIDOS À SEPSE ESTREPTOCÓCICA NO BRASIL: ANÁLISE DE 13 ANOS." Revista ft 29, no. 143 (2025): 45–46. https://doi.org/10.69849/revistaft/ch10202502210945.

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Introdução: A sepse é uma síndrome caracterizada por uma resposta inflamatória exacerbada a uma infecção, levando à disfunção orgânica e risco elevado de morte. Fatores de risco como o uso de cateteres, sonda uretral, imunossupressão, comorbidades, infecções pré-existentes, resistência antimicrobiana e estado nutricional comprometido são determinantes importantes para o desenvolvimento da doença. Objetivos: O objetivo do presente trabalho é realizar o levantamento epidemiológico acerca dos óbitos por casos de septicemia estreptocócica no Brasil, em um período de 13 anos. Bem como realizar o le
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Rivera Teran, V., D. Alpizar-Rodriguez, S. Sicsik, et al. "FRI0546 GENDER DIFFERENCES OF RHEUMATIC DISEASES IN MEXICAN POPULATION: DATA FROM THE MEXICAN BIOLOGICS REGISTRY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 874–75. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6091.

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Background:Most autoimmune diseases are more prevalent in women. Symptom severity, disease progression, response to therapy and overall survival differ between males and females with rheumatic diseases.Objectives:To identify the characteristics of autoimmune diseases presentation and treatment between male and female population using information from the Mexican Adverse Events Registry (BIOBADAMEX).Methods:BIOBADAMEX is a Mexican ongoing cohort that collects the information of patients using biologic and biosimilar drugs since 2016. For this study we included all patients enrolled in the regis
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Vose, Julie, Umberto Vitolo, Pieternella Lugtenburg, et al. "EPCORE NHL-1 follicular lymphoma (FL) cycle (C) 1 optimization (OPT) cohort: Expanding the clinical utility of epcoritamab in relapsed or refractory (R/R) FL." Journal of Clinical Oncology 42, no. 16_suppl (2024): 7015. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.7015.

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7015 Background: Improving the safety of epcoritamab by reducing the incidence and severity of CRS and ICANS may enhance its accessibility and reduce healthcare resource utilization. In the pivotal EPCORE NHL-1 study (phase 1/2; NCT03625037), epcoritamab treatment (tx) led to high overall (ORR) and complete response (CR) rates of 82% and 63%, respectively, in a cohort of patients (pts) with R/R FL. Safety was manageable, with CRS events being primarily low grade. Here we report the first results from the fully enrolled EPCORE NHL-1 FL C1 OPT cohort investigating mitigation strategies for CRS w
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Humphreys, J., K. Dempsey, O. Phelan, L. Boothman, L. Cook, and W. Dixon. "THU0551 SOCIAL CARE USE IN PEOPLE WITH CHRONIC PAIN IN THE UNITED KINGDOM." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 516–17. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2321.

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Background:Chronic pain is a common and disabling health problem and those affected may need support with their activities of daily living (ADLs). Currently there are no data quantifying how much social care support people with chronic pain need.Objectives:To describe formal and informal social care use in people with chronic painMethods:Between June-July 2019, previous participants of theCloudy with a Chance of Painstudy were invited to take part in an online survey, adapted from a validated Personal Social Services Research Unit interview survey. It collected data on whether participants wit
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Abro, Brooj, and Ronald Jackups. "Establishing a Nucleated Count Reflex Trigger for Performing Cell Differential on Cerebrospinal Fluid in Pediatric Patients." American Journal of Clinical Pathology 154, Supplement_1 (2020): S9—S10. http://dx.doi.org/10.1093/ajcp/aqaa137.016.

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Abstract Introduction Analysis of cerebrospinal fluid (CSF) assists in the diagnosis of several disease processes affecting the central nervous system (CNS). Nucleated cell (NC) count and cell differential are two important components of laboratory testing performed to analyze CSF samples. These tests can help diagnose conditions such as infection, inflammation, and malignancy involving the CNS; however, the cell differential, performed manually on a cytospin, is labor-intensive and may divert laboratory resources. Currently, the laboratory at our tertiary care pediatric hospital performs both
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Meadows, Meghan, Meredith Ray, Matthew Smeltzer, et al. "A comparison of two models of multidisciplinary lung cancer care within a community-based healthcare system." Journal of Clinical Oncology 38, no. 29_suppl (2020): 36. http://dx.doi.org/10.1200/jco.2020.38.29_suppl.36.

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36 Background: The Multidisciplinary Thoracic Oncology Conference (MTOC) model is easier to implement than the Multidisciplinary Clinic (MDC) model, but does not directly involve patients in decision-making. We compared the processes and outcomes of lung cancer care between patients discussed in a weekly MTOC versus those seen in a MDC. Methods: Prospective observational study of thoroughness of staging, stage confirmation (defined as biopsy of the stage-defining lesion), National Comprehensive Cancer Network guideline-concordant treatment, overall (OS) and event-free (EFS) survival of lung ca
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Barzi, Afsaneh, Mariana C. Stern, Juanjuan Zhang, Heinz-Josef Lenz, Syma Iqbal, and Lihua Liu. "Gastric cancer (GC) in California Cancer Registry (CCR): One disease, many faces." Journal of Clinical Oncology 32, no. 3_suppl (2014): 30. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.30.

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30 Background: In the US there are approximately 21,000 newly diagnosed GCs with California having the highest number of reported cases per year. Given the disparity in the incidence of the disease among Asians and Hispanics we conducted an analysis of GCs in the CCR to assess the differences in the presentation and outcome of the reported cases from 2000 to 2010. Methods: We identified 26,645 GCs inclusive of Asian, Hispanic, and non-Hispanic whites (NHW); 20% of our population is Asian and 30% of is Hispanic. We examined the tumor characteristics (demographics, stage, anatomical subsite), ag
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Hua, Sophia V., Joshua Petimar, Nandita Mitra, et al. "Philadelphia Beverage Tax and Association With Prices, Purchasing, and Individual-Level Substitution in a National Pharmacy Chain." JAMA Network Open 6, no. 7 (2023): e2323200. http://dx.doi.org/10.1001/jamanetworkopen.2023.23200.

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ImportanceTaxes on sweetened beverages are being implemented around the globe; an understanding of these taxes on individual-level behavior is necessary.ObjectiveTo evaluate the degree to which the sweetened beverage tax in Philadelphia, Pennsylvania, was associated with changes in beverage prices and individual-level purchasing over time at a national pharmacy chain in Philadelphia compared with Baltimore, Maryland.Design, Setting, and ParticipantsUsing a difference-in-differences approach and generalized linear mixed models, this cohort study examined beverage purchases made by loyalty cardh
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Dr., Hira Shahzad Dr. Salman Falak Dr. Tooba Jalees. "A CROSS-SECTIONAL RESEARCH ON PCI (PERCUTANEOUS CORONARY INTERVENTION, BLEEDING SITE & ASSOCIATED RISK FACTORS IN CONTEXT TO MAJOR & MINOR BLEEDING & BLEEDING DEFINITIONS." Indo American Journal of Pharmaceutical Sciences 05, no. 06 (2018): 5892–97. https://doi.org/10.5281/zenodo.1301139.

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<strong><em>Objectives: </em></strong><em>This research aimed to find out the risk factors and bleeding association in the </em><em>patients experiencing PCI (Percutaneous Coronary Intervention). </em> <strong><em>Methodology: </em></strong><em>We included 500 consecutive cases in our </em><em>cross-sectional research who experienced PCI at Allied Hospital, Faisalabad (October, 2016 to December, 2017). We defined bleeding in per the criteria of &ldquo;REPLACE &ndash; 2&rdquo;. </em> <strong><em>Results: </em></strong><em>Male to female proportion in our research was respectively 82 and 418 wit
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