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Journal articles on the topic '579.307 2'

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Published: 4 June 2021
Last updated: 22 June 2024

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1

Cunningham-Smith, K. A., R. Witherdin, L. Hetherington, M. A. Baker, and R. Aitken. "277.The role of pp60c-src tyrosine kinase in sperm capacitation." Reproduction, Fertility and Development 16, no. 9 (2004): 277. http://dx.doi.org/10.1071/srb04abs277.

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A protein kinase A-dependent tyrosine phosphorylation pathway in mammalian spermatozoa has been demonstrated to exist, and is unique to this cell type. As PKA is incapable of directly phosphorylating substrates on tyrosine residues, much research has focused on the identification of an intermediary tyrosine kinase which can be activated by serine/threonine phosphorylation via PKA. Inhibitory studies using genistein, tryphostin, erbstatin and herbimycin A, have demonstrated that the src family of kinases may be responsible for the tyrosine phosphorylation events seen during capacitation (1). Al
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2

Kraggerud, Egil. "Further Textual Issues in theAeneid(2. 749; 5. 300; 9. 539)." Symbolae Osloenses 86, no. 1 (2012): 102–10. http://dx.doi.org/10.1080/00397679.2012.691357.

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3

Maulana, Ucup, Fauziah Fauziah, and Ira Diana Sholihati. "Forward Chaining Algorithm and Simple Additive Weighting (SAW) in Smart HelpDesk Ticketing Information System." CESS (Journal of Computer Engineering, System and Science) 7, no. 1 (2022): 195. http://dx.doi.org/10.24114/cess.v7i1.29750.

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Tujuan dari penelitian ini adalah menjadi solusi membantu tim helpdesk dalam mengelola proses dari membuat tiket hingga penyelesaiannya. Penelitian ini menggunakan algoritma kombinasi Forward Chaining untuk mengelola SLA (Service Level Agreement) pengerjaan tiket dan Simple Additive Weighting (SAW) untuk prioritas pengerjaan tiket. Pengujian telah dilakukan sebanyak 600 data, metode forward chaining mencatat SLA pengerjaan tiket seperti urutan 1 sampai 20 berdurasi 7.9 jam indikator warna hijau, 21 sampai 40 durasi 6 jam berindikator kuning, 41 sampai 70 berdurasi 3 jam indikator hijau, 71 sam
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Yuasa, Mitsuhiro, Kosei Kageyama, Daisuke Kaji, et al. "Low Lymphocyte Count at Day 30 after Single Cord Blood Transplantation Had Negative Impact on Survival, Because of Higher NRM Rate." Blood 134, Supplement_1 (2019): 4482. http://dx.doi.org/10.1182/blood-2019-130662.

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<Introduction> Delayed immune reconstitution after allogeneic transplantation increases the risk of treatment-related mortality, and chronic GVHD. Previous reports showed that absolute lymphocyte count at day 30 (ALC30) was a significant prognostic factor of transplantation, and lower numbers of total CD4+ T cells and naïve CD4+ T cells in particular were associated significantly with higher mortality. However, there is little knowledge about the factors associated with low lymphocyte recovery, especially in cord blood transplantation (CBT). The cut-off value of lymphocyte recove
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Tatte, S. P., N. S. Dhoble, G. C. Mishra, and S. J. Dhoble. "Synthesis characterization and Luminescence Properties of B2BiMg2V3O12 based phosphors with rare earth activated Dy3+ phosphor for solid state lighting." IOP Conference Series: Materials Science and Engineering 1258, no. 1 (2022): 012016. http://dx.doi.org/10.1088/1757-899x/1258/1/012016.

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Highly new efficient vanadate based phosphor B2BiMg2V3O12 (B= K & Na) material incapacitated through rare-earth Dysprosium (Dy) and it was characterized by high temperature solid-state synthesis. Equipped phosphor was established by X-ray diffraction method. In Photo-luminescence measurements shows that the prepared phosphors doped by Dy is excited by near UV ultraviolet light reaching after 300 nm to 380 nm efficiently acceptable to recognize the emission in visible spectrum (in the range 400 nm –570 nm. The highly efficient prepared phosphor doped with lanthanide doped with Dy phosphor l
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Rodrigues, Ariana Larissa de Moura, Ana Carolina de Sá Gomes Cruz Souza, Jéssica Gomes Alcoforado de Melo, and Diego Moura Soares. "Lesões em áreas de furca: fatores etiológicos, diagnóstico e tratamento." ARCHIVES OF HEALTH INVESTIGATION 9, no. 6 (2020): 635–40. http://dx.doi.org/10.21270/archi.v9i6.5110.

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As lesões de furca ocorrem quando a doença periodontal atinge a área de bifurcação dos dentes multirradiculares causando a destruição óssea e perda de inserção no espaço inter-radicular. Existem diversos fatores etiológicos que influenciam no aparecimento dessas lesões e até os dias de hoje o tratamento desse tipo de injúria ainda é um desafio na clínica odontológica. O objetivo deste artigo foi listar, através de uma revisão da literatura, os fatores que influenciam na etiologia da lesão de furca, bem como o seu diagnóstico, prognóstico e tratamento. Fatores como características morfológicas
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7

Stal, Julia, Kimberly A. Miller, Joel E. Milam, et al. "Abstract 2253: Cancer-related follow-up health care utilization and fertility discussion, preservation, and reproductive concerns among diverse adolescent and young adult cancer survivors: A population-based study." Cancer Research 84, no. 6_Supplement (2024): 2253. http://dx.doi.org/10.1158/1538-7445.am2024-2253.

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Abstract Purpose: To examine cancer-related follow-up (CRFU) health care utilization associated with fertility experiences among diverse adolescent and young adult (AYA) cancer survivors. Methods: Project Milestones is an ongoing survey study evaluating life outcomes among AYAs diagnosed with cancer at age 21-39 in Los Angeles (LA) County. AYAs had an initial 5-year survival probability of ≥50% and are currently 3-10 years post-diagnosis. A registry-based recruitment strategy through the SEER-affiliated LA Cancer Surveillance Program was used. Results: Overall, 1442 AYAs responded (Table 1). C
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SEKHAR, M. CHANDRA, B. GOPALA KRISHNA, M. MAHESH KUMAR, and S. V. SURYANARAYANA. "HIGH DIELECTRIC CONSTANT AND NONLINEAR ELECTRIC RESPONSE IN Bi2Sr2SmCu2Oy." Modern Physics Letters B 10, no. 27 (1996): 1365–77. http://dx.doi.org/10.1142/s0217984996001541.

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Samples with the nominal composition Bi 2 Sr 2 SmCu 2 O y were prepared by solid state reaction method. From the room temperature X-ray diffraction data, it was found that the sample is similar to the Bi-2212 structure. DC electrical resistivity was done from 80 K to 573 K and the impedance measurements were performed from 80 K to 573 K at different frequencies in the range of 10 kHz to 800 kHz. The sample Bi 2 Sr 2 SmCu 2O y has exhibited semiconducting behavior in the low temperature region (80 K to 343 K), metallic behavior in the temperature range of 343 K to 443 K and again semiconducting
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9

Ntemgwa, Michel, Mark A. Wainberg, Maureen Oliveira, et al. "Variations in Reverse Transcriptase and RNase H Domain Mutations in Human Immunodeficiency Virus Type 1 Clinical Isolates Are Associated with Divergent Phenotypic Resistance to Zidovudine." Antimicrobial Agents and Chemotherapy 51, no. 11 (2007): 3861–69. http://dx.doi.org/10.1128/aac.00646-07.

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ABSTRACT Mutations in the RNase H domain of human immunodeficiency virus type 1 RT have been reported to cause resistance to zidovudine (ZDV) in vitro. However, very limited data on the in vivo relevance of these mutations in patients exist to date. This study was designed to determine the relationship between mutations in the RNase H domain and viral susceptibility to nucleoside analogues. Viruses harboring complex thymidine analogue mutation (TAM) and nucleoside analogue mutation (NAM) profiles were evaluated for their phenotypic susceptibilities to ZDV, tenofovir (TNF), and the nonapproved
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10

Keane, M. G., G. J. More O'Ferrall, J. Connolly, and P. Allen. "Carcass composition of serially slaughtered Friesian, Hereford × Friesian and Charolais × Friesian steers finished on two dietary energy levels." Animal Science 50, no. 2 (1990): 231–43. http://dx.doi.org/10.1017/s0003356100004682.

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ABSTRACTThe carcass composition of Hereford × Friesian (HE), Friesian (FR) and Charolais × Friesian (CH) steers finished on diets of high (H) and medium (M) dietary metabolizable energy (ME) concentrations and slaughtered at low (L), normal (N) and heavy (W) carcass weights was examined in a 3 × 2 × 3 (no. = 9 per individual treatment) factorial experiment. A pre-finishing slaughter group of nine animals of each breed type was also included, giving a total 189 animals in 21 experimental groups. ME concentrations of the H and M diets which were offered ad libitum were 12·6 and 10·4 MJ/kg dry ma
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Yang, Qi, Xiao-Lei Zhu, Ting-Ting Lu, Jian Ma, Yin Hang, and Wei-Biao Chen. "A 5.9-mJ 500-Hz Electro-Optic Q -Switched 1053 nm Nd:LiLuF 4 Laser." Chinese Physics Letters 31, no. 2 (2014): 024205. http://dx.doi.org/10.1088/0256-307x/31/2/024205.

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12

Oganesyan, Oganes G., A. A. Grdikanyan, S. S. Yakovleva, and V. R. Getadaryan. "THE PARTIAL DISCEMETOREXIS WITHOUT TRANSPLANTATION IN CASE OF ENDOTHELIAL DYSTROPHY OF CORNEA." Medical Journal of the Russian Federation 23, no. 6 (2017): 302–7. http://dx.doi.org/10.18821/0869-2106-2017-23-6-302-307.

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During the last 20 years, the penetrating keratoplasty gave in its leading place to selective lamellar keratoplasty when pathologically altered layers of cornea are selectively replaced, including endothelium. The main technical task of all procedures of endothelial keratoplasty is an obligatory complete or almost complete post-operative adjacency of endothelial transplant to stroma of recipient. However, there are publications concerning resorption of edema in case of separation of endothelial transplant and even at its absence. The purpose of study. To analyze, on the basis of limited clinic
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13

Shavlovskaya, O. A., I. A. Bokova, I. D. Romanov, and N. I. Shavlovsky. "Efficacy of undenatured and hydrolyzed type II collagen in the treatment of pain syndrome." Russian Medical Inquiry 6, no. 10 (2022): 571–75. http://dx.doi.org/10.32364/2587-6821-2022-6-10-571-575.

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Collagens play an important structural role and contribute to the mechanical properties, organization and shape of tissues. In musculoskeletal system diseases (MSD), the amount of type II collagen in the cartilage extracellular matrix significantly decreases. Degradation and reduction of type II collagen are associated with osteoarthritis (OA). At present, SYSADOA (Symptomatic Slow Acting Drugs for Osteoarthritis) are widely used in the treatment of OA for oral and parenteral use. Besides, increased attention has been paid to the new treatment methods for OA based on a new promising type II co
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14

Xue, I. B., P. G. Davey, and G. Phillips. "Variation in postantibiotic effect of clindamycin against clinical isolates of Staphylococcus aureus and implications for dosing of patients with osteomyelitis." Antimicrobial Agents and Chemotherapy 40, no. 6 (1996): 1403–7. http://dx.doi.org/10.1128/aac.40.6.1403.

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Initial measurements of postantibiotic effect (PAE) were made by a standard laboratory method (exposure to 1 mg of clindamycin per liter for 1 h). The range of PAE for 21 strains of Staphylococcus aureus isolated from osteomyelitis patients was 0.4 to 3.9 h, which markedly exceeded the coefficient of variation for the method (6 to 19%). Exposure of S. aureus to three doses of clindamycin at 8-h intervals had no consistent effect on either PAE or MIC. The PAE was dependent on both concentration and duration of exposure to clindamycin: for example, the PAEs for one strain were 1.7 h after exposu
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15

Prueksaritanond, Suartcha, Aram Barbaryan, Aibek E. Mirrakhimov, Palacci Liana, Alaa M. Ali, and Alan D. Gilman. "A Puzzle of Hemolytic Anemia, Iron and Vitamin B12 Deficiencies in a 52-Year-Old Male." Case Reports in Hematology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/708489.

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A 52-year-old male with no significant past medical history reports increasing generalized fatigue and weakness for the past 2 weeks. Physical examination reveals jaundice and pallor without organomegaly or lymphadenopathy. His hemoglobin was 5.9 g/dL with a mean corpuscular volume of 87.1 fL and elevated red blood cell distribution width of 30.7%. His liver function test was normal except for elevated total bilirubin of 3.7 mg/dL. Serum LDH was 701 IU/L, and serum haptoglobin was undetectable. Further investigation revealed serum vitamin B12 of <30 pg/mL with elevated methylmalonic acid an
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16

Christopherson, Kent W., Laura A. Paganessi, Darilyn R. Rhoades, et al. "Abnormally High Levels of Circulating CD34+CD38−, CD34+CD38+, and CD10+ Hematopoietic Stem and Progenitor Cells in the Peripheral Blood of B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients Suggest the Presence of Additional Therapeutic Target Cells." Blood 110, no. 11 (2007): 4711. http://dx.doi.org/10.1182/blood.v110.11.4711.4711.

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Abstract Chronic Lymphocytic Leukemia (CLL) is a lymphoproliferative disorder manifested by a clonal expansion of mature long-lived functionally defective lymphocytes that are predominantly of B-cell origin (>95% of cases). CLL cells typically express the pan-B-cell antigens CD19 and CD20 as wells as CD5, an antigen of mature T-cells, which is present in 95% of B-CLL patients and is helpful for diagnosis. The disease has a median survival of 8–10 years. Asymptomatic patients (RAI stages 0–2) are often not treated. RAI stages 3 & 4 are generally treated. Current therapies for CLL include
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17

Hambley, Trevor W., Keith G. Lewis, David J. Tucker та Peter Turner. "Stereochemical Study of a 13β,28-Epoxyoleanane". Australian Journal of Chemistry 51, № 4 (1998): 343. http://dx.doi.org/10.1071/c97109.

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The stereochemistry of 3β-acetoxy-12α-bromo-13β,28-epoxyoleanan-16α-ol (2b) has been examined by n.m.r. methods and established by an X-ray crystallographic examination. Steric hindrance of the 16α-hydroxy group is shown not to be as great as previously reported. The bromo epoxide (2b), C32H51BrO4, M 579·66, crystallized in the orthorhombic space group P 212121 with a 16·118(2), b 16·615(3), c 11·024(7) Å, V 2952(1) Å3 , Dc(Z = 4) 1·304 g cm-3 , N = N(unique) = 1954, No 1731 [I > 2·5σ(I)], Nvar = 335, conventional R 0· 039, Rw 0·038.
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18

Ozdanova, Jitka, Helena Ticha, and Ladislav Tichy. "Some Physical Properties of Li2O-TiO2-TeO2 and BaO-TiO2-TeO2 Glasses." Advanced Materials Research 39-40 (April 2008): 185–88. http://dx.doi.org/10.4028/www.scientific.net/amr.39-40.185.

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Homogeneous yellowish and well transparent glasses (Li2O)x(TiO2)x(TeO2)1-2x and (BaO)x(TiO2)x(TeO2)1-2x , (x = 0.075, 0.1, 0.125) were prepared from corresponding oxides (purity 99+%). For prepared glasses the optical gap values were found in the region 3.2 eV – 3.4 eV and the temperature (T) coefficient of the optical gap (γ) varies in the narrow region 5.3×10-4 eV/K to 5.9×10-4 eV/K for 300 K < T < 580 K. Estimated values of non-linear refractive index (n2) were found in the region n2 [m2W-1] = 2.7×10-18 – 3.5×10-18 close to n2 values for similar glasses. Raman spectra measured indicat
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Di Veroli, Ambra, Marianna De Muro, Alessandro Andriani, et al. "Incidence of Early Thrombosis in Myeloproliferative Neoplasms (MPN): A Prospective Analysis from the Gruppo Laziale of Ph-Negative MPN." Blood 128, no. 22 (2016): 1951. http://dx.doi.org/10.1182/blood.v128.22.1951.1951.

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Abstract Background Thrombotic episodes are the major complication in the follow-up of Philadelphia negative Myeloproliferative Neoplasms (MPN), with high morbidity and mortality, as reported in several retrospective studies. At present, however, few prospective data are available on the early incidence of these complications. Methods To address this issue, we report on 1087 patients [M/F 508/579, median age 67.6 years, interquartile range (IQR) 55.2 - 75.9] with newly diagnosed MPN enrolled in the prospective database of our regional cooperative group since January 2011. Of them, 571 (52.5%)
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Ghosh, D., S. Hussain, B. Ghosh, R. Bhar, and A. K. Pal. "Stress and Grain Boundary Properties of GaN Films Prepared by Pulsed Laser Deposition Technique." ISRN Materials Science 2014 (March 17, 2014): 1–10. http://dx.doi.org/10.1155/2014/521701.

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Polycrystalline gallium nitride films were successfully deposited on fused silica substrates by ablating a GaN target using pulsed Nd-YAG laser. Microstructural studies indicated an increase in the average crystallite size from ~8 nm to ~70 nm with the increase in substrate temperature from 300 K to 873 K during deposition. The films deposited here were nearly stoichiometric. XPS studies indicated two strong peaks located at ~1116.6 eV and ~395 eV for Ga2p3/2 and a N1s core-level peak, respectively. The films deposited at substrate temperature above 573 K are predominantly zinc blende in natur
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Singh, Khushwant, Matthew Huff, Jianyang Liu, et al. "Chromosome-Scale, De Novo, Phased Genome Assemblies of Three Australian Limes: Citrus australasica, C. inodora, and C. glauca." Plants 13, no. 11 (2024): 1460. http://dx.doi.org/10.3390/plants13111460.

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Huanglongbing (HLB) is a severe citrus disease worldwide. Wild Australian limes like Citrus australasica, C. inodora, and C. glauca possess beneficial HLB resistance traits. Individual trees of the three taxa were extensively used in a breeding program for over a decade to introgress resistance traits into commercial-quality citrus germplasm. We generated high-quality, phased, de novo genome assemblies of the three Australian limes using PacBio long-read sequencing. The genome assembly sizes of the primary and alternate haplotypes were determined for C. australasica (337 Mb/335 Mb), C. inodora
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Röhling, Martin, Kerstin Kempf, Winfried Banzer, et al. "A High-Protein and Low-Glycemic Formula Diet Improves Blood Pressure and Other Hemodynamic Parameters in High-Risk Individuals." Nutrients 14, no. 7 (2022): 1443. http://dx.doi.org/10.3390/nu14071443.

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Low-caloric formula diets can improve hemodynamic parameters of patients with type 2 diabetes. We, therefore, hypothesized that persons with overweight or obesity can benefit from a high-protein, low-glycemic but moderate-caloric formula diet. This post-hoc analysis of the Almased Concept against Overweight and Obesity and Related Health Risk- (ACOORH) trial investigated the impact of a lifestyle intervention combined with a formula diet (INT, n = 308) compared to a control group with lifestyle intervention alone (CON, n = 155) on hemodynamic parameters (systolic and diastolic blood pressure (
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Hagiwara, Yoshiaki, Christian Henkel, and William A. Sherwood. "Monitoring of extragalactic water masers with the MPIfR 100-m telescope." Symposium - International Astronomical Union 206 (2002): 392–95. http://dx.doi.org/10.1017/s0074180900222766.

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We present single-dish monitoring of the 22 GHz water maser lines from the Seyfert 2 galaxies NGC 3079, M51(NGC 5194), NGC 5793, and the radio galaxy NGC 315 with the Effelsberg 100-m radio telescope. During the monitoring period of 1995 − 2001, the H2O masers flared in M51 and NGC 5793, while maser emission from NGC 315 was not detected in 1996 and 2000. During 2000, we discovered new red-shifted velocity features in NGC 3079 and blue-shifted features in M51. These velocity components are crucial to model the distribution of maser emission in each galaxy.
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24

Silverberg, Nanette, Harry M. Meister, and Mark Lebwohl. "571 - Case series of topical 1.5% ruxolitinib cream for pediatric vitiligo." British Journal of Dermatology 190, Supplement_2 (2024): ii71—ii72. http://dx.doi.org/10.1093/bjd/ljad498.073.

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Abstract Introduction/Background Pediatric Vitiligo affects 1.52% of 4-11-year-olds within the United States and 2.16% of 12-17-year-olds with non-segmental disease affecting 65% and 69% respectively (1). The FDA has not approved any medications for vitiligo for children younger than 12 years of age. Additionally, about one-third of pediatric vitiligo is segmental (1), and there is no FDA-approved topical agent for segmental vitiligo in any pediatric age group (2). Objectives To identify the efficacy of 1.5% ruxolitinib cream for pediatric vitiligo in clinical practice. Methods An IRB-exempted
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Shi, Feng, Yu Fen Gu та Cui Xia Li. "Growth of β-Ga2O3 Nanoparticles Doped with Tin by Ni2+ Catalyzed Chemical Vapor Deposition". Advanced Materials Research 873 (грудень 2013): 200–205. http://dx.doi.org/10.4028/www.scientific.net/amr.873.200.

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Sn-doped monoclinic β-Ga2O3 nanoparticles were successfully fabricated on Si (111) substrates with NiCl2 as a catalyst by chemical vapor deposition using metallic gallium and oxygen as sources. The composition, crystal structure, morphology, and optical properties were characterized by X-ray diffraction, scanning electron microscopy, Fourier-transform infrared spectrophotometry (FTIR), and photoluminescence, respectively. The results demonstrate that the sample was monoclinic β-Ga2O3 nanoparticles with diameters approximately ranging from 200~300 nm. Well-defined prominent absorption bands loc
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Depauw, R. M., R. E. Knox, A. K. Singh, T. N. Mccaig, J. M. Clarke, and R. D. Cuthbert. "NRG010 General Purpose spring wheat." Canadian Journal of Plant Science 93, no. 3 (2013): 549–55. http://dx.doi.org/10.4141/cjps2012-309.

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DePauw, R. M., Knox, R. E., Singh, A. K., McCaig, T. N., Clarke, J. M. and Cuthbert, R. D. 2013. NRG010 General Purpose spring wheat. Can. J. Plant Sci. 93: 549–555. Based on 26 trials over 2 yr, the cultivar NRG010 yielded similar to the General Purpose checks Hoffman and AC Andrew. NRG010 had significantly shorter stature than Hoffman. NRG010 had a large white kernel intermediate in size to AC Andrew and Hoffman. NRG010 expressed resistance to prevalent races of leaf rust, stem rust and common bunt, and moderate susceptibility to prevalent races of loose smut and fusarium head blight. NRG010
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Bunak, M. S., M. V. Vishnyakova, G. A. Stashuk, and R. G. Biktimirov. "Using the arterial spins labeling method (ASL-perfusion) for evaluation of glioblastoma residual tissue." Journal of radiology and nuclear medicine 99, no. 6 (2019): 305–9. http://dx.doi.org/10.20862/0042-4676-2018-99-6-305-309.

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Objective. To evaluate the efficiency of ASL-perfusion as a method of estimating of hemodynamics and detection of residual tumor tissue after surgical treatment of glioblastoma.Material and methods. 56 patients after brain tumor’s surgical resection of glioblastoma (GRADE IV). CBF values were determined in 3 different areas - in the presumed tumor tissue with maximum perfusion, in the postoperative scar tissue and in the deep white matter of the opposite hemisphere. All patients were divided into 2 groups according to CBF value.Results. 1st group: 38 (67.9%) patients - the average CBF in suspe
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Nguyen Van, Long, and Hoang Son Tong Phuoc. "Temporal changes of key marine habitats in the World Biosphere Reserve of Cu Lao Cham - Hoi An, Quang Nam province." Tạp chí Khoa học và Công nghệ Biển 21, no. 2 (2021): 191–200. http://dx.doi.org/10.15625/1859-3097/15063.

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Assessments of marine habitats have played an essential role in the management and sustainable uses of marine biodiversity resources. Spatial and temporal changes in distribution and area of crucial marine habitats in the World Biosphere Reserve of Cu Lao Cham - Hoi An were assessed using remote sensing technology (Landsat 5-TM, SPOT4, and AVNIR2 Sentinel 2-MS) and aerial images in combination with ground-truthing at 60 key sites in the year of 2016 and back-interpretation for the years of 2004 and 2008. This study shows some 579 ha of coral reefs, 117 ha of mangrove forest (mainly by Nypa pal
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Ahn, Hee Kyung, Jee Hung Kim, Mirae Kim, et al. "Abstract P5-03-14: Prevalence of germline BRCA mutations in unselected Korean patients with HER2-negative breast cancer: A Prospective cohort study." Cancer Research 83, no. 5_Supplement (2023): P5–03–14—P5–03–14. http://dx.doi.org/10.1158/1538-7445.sabcs22-p5-03-14.

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Abstract Backgrounds Since OlympiAD study, National Comprehensive Cancer Network guideline recommends assessment of germline BRCA1/2 mutation in all patients with recurrent or metastatic breast cancer to identify candidates for PARP inhibitor therapy, which is not always possible in clinical practice due to limited resources for testing. Data on the prevalence of gBRCA mutation is still lacking, especially in patients with non-high risk for hereditary breast and ovarian cancer syndrome. In this study, we investigated prevalence of gBRCA mutation in unselected Korean patients with HER2-negative
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Zsolt, Szentkereszty, Trungel Enikő, Pósán János, Sápy Péter, Szerafin Tamás, and Sz Kiss Sándor. "Áthatoló mellkassérülések diagnózisának és kezelésének időszerű kérdéseir." Magyar Sebészet 60, no. 4 (2007): 199–204. http://dx.doi.org/10.1556/maseb.60.2007.4.1.

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Absztrakt Bevezetés: Az áthatoló mellkasi sérülések sikeres kezelése a korrekt, gyors diagnózisban és az adekvát sebészi kezelésben rejlik. A szerzők 109 mellkassérült beteg kapcsán értékelik a diagnózis és a kezelés aktuális kérdéseit a szövődmények és az eredmények tükrében. Betegek és módszerek: A 82 férfi és 27 nő sérült átlagos életkora 37,8 év volt. A sérülést 104 (95,4%) esetben szúrás, 4 (3,7%) esetben lövés és 1 (0,9%) esetben robbanás okozta. A 41 szív- és szívburoksérültnél 19 (46,3%) mellkas-rtg, 9 (22%) echocardiographia és 2-2 CT-vizsgálat, illetve diagnosztikus VATS történt. A 4
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31

Family, Leila, Su-Jau Yang, Zandra Klippel, et al. "Risk of Febrile Neutropenia (FN) in Select Myelosuppressive Chemotherapy Regimens." Blood 126, no. 23 (2015): 3257. http://dx.doi.org/10.1182/blood.v126.23.3257.3257.

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Abstract Introduction Febrile neutropenia (FN) is a serious adverse effect of myelosuppressive chemotherapy, which often results in hospitalization and chemotherapy dose modification. FN risk depends on patient characteristics and chemotherapy regimen risk. Understanding the FN risk associated with individual chemotherapy regimens can help guide the use of prophylactic granulocyte colony-stimulating factor (G-CSF) and patient monitoring. To this end, the NCCN has classified regimens into high (≥20%), intermediate (10%-20%), or low (<10%) FN risk based primarily on clinical trial data. Howev
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32

Schmickler, Wolfgang. "Rundum nützlich: Elektrochemisches Praktikum. Von Rudolf Holze. B. G. Teubner, Stuttgart 2001. 302 Seiten, brosch. 32,72 Euro. ISBN 3-519-03614-2." Nachrichten aus der Chemie 50, no. 2 (2002): 192. http://dx.doi.org/10.1002/nadc.20020500226.

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33

Martín Riego, Manuel. "María Antonia Bel Bravo, La familia en la historia (Madrid, Encuentro, 2000) 302 pp. 230 X 150. ISBN 84-7490-570-2." Isidorianum 10, no. 19 (2001): 271–72. http://dx.doi.org/10.46543/isid.0210.1014.

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34

Hafeez, Shaista, Karole Warren-Oseni, Helen McNair, et al. "Prospective phase 1 study assessing feasibility of IMRT and IGART to deliver simultaneous integrated high-dose tumor boost (up to 70 Gy) for the radical treatment of localized muscle-invasive bladder cancer." Journal of Clinical Oncology 33, no. 7_suppl (2015): 307. http://dx.doi.org/10.1200/jco.2015.33.7_suppl.307.

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307 Background: Advances in IGART offer individualized solutions to improve target coverage and reduce normal tissue irradiation allowing opportunity to increase radiation tumour dose and spare normal bladder. Methods: A library of 3 IMRT plans were created (small, medium and large) from planning CT scans performed at 30 and 60 minutes; treating whole bladder to 52 Gy and tumour to 70 Gy in 32 fractions. Where normal tissue dose constraints were not met consideration was made to boosting tumour to lower dose (68 Gy-64 Gy). Cone beam CT (CBCT) imaging was performed prior to each fraction. Appro
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35

Schlegelmilch, Michael, Salima Punja, Hsing Jou, et al. "Observational Study of Pediatric Inpatient Pain, Nausea/Vomiting and Anxiety." Children 6, no. 5 (2019): 65. http://dx.doi.org/10.3390/children6050065.

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Background: The prevalence and severity of pain, nausea/vomiting, and anxiety (PNVA) among hospitalized children is not well established. We describe the prevalence and severity of PNVA among hospitalized patients from oncology, general pediatrics, and cardiology services in a tertiary care center. Methods: Patients were recruited on admission and enrolled if their caregiver consented, spoke English, and were anticipated to stay 2–30 days. Symptoms were measured weekdays using age-validated tools. PNVA symptoms were described and compared. Results: We enrolled 496 (49.4%) patients of 1005 admi
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36

Lambert-Falls, R., M. A. Deutsch, C. Desch, K. Zhou, and E. Perez. "Phase III adjuvant trial of concurrent epirubicin/taxane vs. sequential epirubicin/cyclophosphamide followed by taxane for node positive breast cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 573. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.573.

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573 Background: This study evaluates whether concurrent epirubicin/taxane (ET) improves disease-free survival (DFS) at 3 yrs compared to the sequential combination of epirubicin/cyclophosphamide followed by a taxane (EC>T) in pts with operable node (+) breast cancer. Methods: Eligible pts were randomized to receive either ET (E 75 mg/m 2) for 8 cycles q21 days or EC>T (E 90 mg/m 2, C 600 mg/m2) for 4 cycles, followed by 4 cycles of a taxane q21 days. Choice of T (paclitaxel 175 mg/m2 or docetaxel 75 mg/m 2) was at the physician’s discretion. The primary endpoint is DFS. A 0.10 increase i
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37

Pronzato, Paolo, Giorgio Mustacchi, Daniele Giulio Generali, and Alberto Bottini. "Complementary role of Ki67 index and 70-gene signature (MammaPrint) high-risk patients in the St Gallen risk group with uncertain chemotherapy suggestion." Journal of Clinical Oncology 30, no. 15_suppl (2012): 579. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.579.

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579 Background: St Gallen (SG) Consensus Panel on adjuvant treatment recommends the use of proliferation markers and multigene assays when choosing the appropriate treatment in addition to traditional parameters. Ki67 predictive/prognostic value is widely accepted; we tested its role in increasing the accuracy of risk prediction among Mammaprint (MP) /High(HR) or /Low Risk (LR) breast cancer patients with a SG risk uncertain for chemotherapy selection. Methods: MP was determined (courtesy of Agendia, Amsterdam) in 3 Italian Hospitals on 305 consecutive samples of breast cancer patients. We foc
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38

Guralnick, R. M., and G. R. Robinson. "Addendum to paper “On the commuting probability in finite groups” by R.M. Guralnick and G.R. Robinson [J. Algebra 300 (2) (2006) 509–528]." Journal of Algebra 319, no. 4 (2008): 1822. http://dx.doi.org/10.1016/j.jalgebra.2007.06.014.

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39

Panswad, Thongchai, and Somkid Wongchaisuwan. "Mechanisms of Dye Wastewater Colour Removal by Magnesium Carbonate-Hydrated Basic." Water Science and Technology 18, no. 3 (1986): 139–44. http://dx.doi.org/10.2166/wst.1986.0045.

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The effects of alkaline magnesium carbonate-hydrated basic as a coagulant, have been investigated in colour reduction experiments using Jar Test apparatus. The raw wastewater was synthetic containing 300 mg/dm3 reactive red dye 519. It has been found that no single flocculant (Mg(OH)2, Ca(OH)2 or CaCO3) can satisfactorily effect colour removal. The effective colour reduction achieved using alkaline magnesium carbonate-hydrated basic has been attributed to the synergistic sorbing capacity of the flocculants Mg(OH)2 and CaCO3.
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40

Richters, Lisa Katharina Katharina, Oleg Gluz, Nana Weber-Lassalle, et al. "Pathological complete response rate and survival in patients with BRCA-associated triple-negative breast cancer after 12 weeks of de-escalated neoadjuvant chemotherapy: Translational results of the WSG-ADAPT TN randomized phase II trial (NCT01815242)." Journal of Clinical Oncology 39, no. 15_suppl (2021): 579. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.579.

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579 Background: The phase II trial WSG-ADAPT TN randomized triple-negative breast cancer (TNBC) patients to receive 12 weeks of neoadjuvant nab-paclitaxel (nab-pac) combined with carboplatin (carbo) vs gemcitabine (gem) and showed a substantial improvement of pathological complete response (pCR: ypT0/is, ypN0) with carbo (45.9% vs 28.7%). pCR had a strong favorable impact on iDFS after 3-year follow-up. Distribution of tumor mutations in BC-associated genes and impact of BRCA mutation status on pCR and outcome are analyzed here. Methods: NGS-based mutational analysis of BRCA1/2 and 18 further
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41

Giordano, Federica, Stefania Lenna, Riccardo Rampado, et al. "Abstract 307: Ponatinib loaded leukocyte-based nanoparticles: A new platform for treating osteosarcoma." Cancer Research 82, no. 12_Supplement (2022): 307. http://dx.doi.org/10.1158/1538-7445.am2022-307.

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Abstract The introduction of targeted anticancer drugs has revolutionized treatment. Multi-tyrosine kinase inhibitors (TKIs) are potential therapeutics targeting specific signaling pathways that contribute to cancer progression, including sarcomas. Osteosarcoma is the most common pediatric tumor with a worldwide incidence of 3.4 cases/million annually but without effective treatment. Of the TKIs, Ponatinib demonstrated potent anti-tumor activity; however, it received an FDA black box warning for potential side effects. New treatment and delivery systems must be identified to use Ponatinib clin
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42

Wang, W., T. Zhang, L. Wang, and H. Song. "FRI0472 DIAGNOSIS AND MANAGEMENT OF ADENOSINE DEAMINASE 2 DEFICIENCY CHILDREN: THE EXPERIENCE FROM CHINA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 833.1–833. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3481.

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Background:Adenosine deaminase 2 deficiency (DADA2) is a rare antoinflammatory disease caused by mutations in ADA2 gene, few Chinese cases have been reported.Objectives:To describe and compare the clinical features, genotypes, and treatments of Chinese DADA2 patients and foreign cases.Methods:Primary immunodeficiency disease Panel or Whole Exome Sequencing was performed to suspected subjects, and assays for adenosine deaminase 2(ADA2) enzyme activity were also carried out to them and their parents. Case reports of Chinese and foreign patients with DADA2 were searched from PubMed and Chinese do
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43

Rathkopf, Dana E., Michael J. Morris, Daniel Costin Danila, et al. "A phase I study of the androgen signaling inhibitor ARN-509 in patients with metastatic castration-resistant prostate cancer (mCRPC)." Journal of Clinical Oncology 30, no. 15_suppl (2012): 4548. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.4548.

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4548 Background: ARN-509 is a novel small molecule AR antagonist that impairs AR nuclear translocation and binding to DNA, inhibiting tumor growth and promoting apoptosis, with no partial agonist activity. (Clegg et al., 2012) We conducted a phase I trial to assess safety, pharmacokinetics (PK), and determine the recommended phase II dose (RP2D). Methods: Eligible patients with mCRPC received ARN-509 orally on a continuous daily dosing schedule. Seven doses (30, 60, 90, 120, 180, 240, and 300 mg) were tested using standard 3x3 dose escalation criteria. Once drug concentrations were achieved th
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44

Mittra, Joy, Geogy Jiju Abraham, Manoj Kesaria, et al. "Role of Substrate Temperature in the Pulsed Laser Deposition of Zirconium Oxide Thin Film." Materials Science Forum 710 (January 2012): 757–61. http://dx.doi.org/10.4028/www.scientific.net/msf.710.757.

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Thin films of zirconium oxide have been deposited using pulsed laser deposition on Zr-base alloy substrates, held at 300 K, 573 K and 873 K, in order to understand the effect of substrate temperature on the deposited film. In this study, a KrF excimer laser having 30 ns pulse width and 600 mJ energy at source has been used for depositing the films from a sintered ZrO2 target using a laser fluence of 5 J.cm-2. After visual observation, deposited thin films were examined using Raman Spectroscopy (RS) and X-ray Photo-electron Spectroscopy (XPS). It has been found that the oxide deposited at 300 K
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45

Grijalba-Bendeck, Marcela, Jorge Paramo, and Matthias Wolff. "Catch composition of deep-sea resources of commercial importance in the Colombian Caribbean." Revista de Biología Marina y Oceanografía 54, no. 2 (2019): 194. http://dx.doi.org/10.22370/rbmo.2019.54.2.1891.

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Recent studies in the Colombian Caribbean Sea describe the potential for a new deep-sea crustacean fishery between 200 a 550-m depth. In order to support appropriate management plans for their sustainable utilization, the goal of the present study was to identify the catch composition and to detect general trends in the bathymetric distribution of the main four biological categories (crustaceans, teleostean, chondrichthyes and molluscs), in relation to depth strata. A total catch per unit area of 8,759 ind. km-2 and 226 kg km-2 was reported and the major contribution was supported by teleostea
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46

Ueno, Takayuki, XiWen Bi, Guangyu Liu, et al. "International retrospective cohort study of locoregional and systemic therapy in oligometastatic breast cancer (OLIGO-BC1)." Journal of Clinical Oncology 38, no. 15_suppl (2020): 1025. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1025.

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1025 Background: Systemic therapy is the standard care in metastatic breast cancer (BC). However, retrospective studies demonstrated survival benefits of locoregional and systemic (combination) therapy in oligometastatic BC. To clarify it, the Federation of Asian Clinical Oncology conducted an international retrospective cohort study (OLIGO-BC1) (UMIN No.000030047). Methods: Oligometastatic BC patients diagnosed from 2007 to 2012 were registered. “Oligometastases” is defined as low volume metastatic disease with limited number and size of metastatic lesions up to five and not necessarily in th
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47

Huuskonen, Arto, Maiju Pesonen, and Maarit Hyrkäs. "Liharotuisten sonnien ja hiehojen kasvu- ja teurasominaisuudet." Suomen Maataloustieteellisen Seuran Tiedote, no. 28 (January 31, 2012): 1–7. http://dx.doi.org/10.33354/smst.75461.

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Tutkimuksella haluttiin selvittää liharotuisten nautojen kasvu- ja teurasominaisuuksia. Tutkimusaineistona oli teurastamoilta saatu naudan ruhojen teurasaineisto, johon yhdistettiin ProAgria Maatalouden Laskentakeskuksen kautta saadut rotutiedot. Teurastamoaineistoa oli käytössä HK Agri Oy:ltä ja Snellman Lihanjalostus Oy:ltä vuodesta 2007 lähtien, A-Tuottajat Oy:ltä vuodesta 2008 lähtien ja Saarioinen Lihanjalostus Oy:ltä vuodesta 2010 lähtien. Hiehojen osalta alle 300 ja yli 550 vrk:n ikäiset eläimet jätettiin datasta pois. Vastaavasti sonnien osalta alle 365 ja yli 660 vrk:n ikäiset eläimet
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48

Zhevnenko, Sergei, Danil V. Vaganov, and Eugene Gershman. "The Liquid Bismuth Penetration from Solid Bi2Te3: Grain Boundary Embrittlement and Effect of Impurities." Defect and Diffusion Forum 309-310 (March 2011): 265–70. http://dx.doi.org/10.4028/www.scientific.net/ddf.309-310.265.

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The liquid bismuth penetration from solid bismuth telluride (Bi2Te3) into grain boundaries of copper and copper-based solid solutions was studied. The experiments were performed at 570 oC in hydrogen atmosphere. The copper specimens were annealed from 10 to 90 minutes. Solid Bi2Te3 didn’t contact with copper specimens during experiments, so copper was covered by the decay products of Bi2Te3 through the gas phase. Liquid Bi penetration leads to grain boundary embrittlement of copper. We assumed that the depth of penetration is equal to the length of cracks which are formed after sample bending.
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49

Rathkopf, Dana E., Daniel Costin Danila, Michael J. Morris, et al. "Phase I/II safety and pharmacokinetic (PK) study of ARN-509 in patients with metastatic castration-resistant prostate cancer (mCRPC): Phase I results of a Prostate Cancer Clinical Trials Consortium study." Journal of Clinical Oncology 30, no. 5_suppl (2012): 43. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.43.

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43 Background: In CRPC, androgen receptor (AR) overexpression is associated with resistance to first-generation anti-androgen therapy such as bicalutamide. ARN-509 is a novel small molecule AR antagonist that impairs AR nuclear translocation and binding to DNA, inhibiting tumor growth and promoting apoptosis, with no partial agonist activity. Preclinical data shows that ARN-509 binds AR with 5-fold greater affinity than bicalutamide, and induces tumor regression in hormone-sensitive and CRPC xenograft models. Methods: In this open-label, Phase 1/2 study, mCRPC patients received ARN-509 orally
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50

Galstyan, Irina A., Nelya A. Metlyaeva, Mikhail V. Konchalovsky, et al. ""Subacute" course of chronic radiation syndrome." Russian Journal of Occupational Health and Industrial Ecology 61, no. 9 (2021): 572–79. http://dx.doi.org/10.31089/1026-9428-2021-61-9-572-579.

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Introduction. The use of ionizing radiation as a production factor in the late 1940s - early 1950s. began in the absence of a clear understanding of the permissible radiation doses for workers, as well as knowledge of diagnostic criteria and developed therapeutic measures for developing chronic radiation sickness (CRS). Since then, a great deal of experience has been accumulated in the diagnosis and treatment of CRS. Currently, there are no conditions at the workplace for chronic exposure of workers in doses exceeding the permissible ones. However, taking into account the constant expansion of
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