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Journal articles on the topic "580.956 93"
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Rodríguez, Odile, Benito Faure, Roberto Benitez, Rita M. Carballo, and Jeny Capote. "Avances en el estudio de la resistencia a bacteriosis común del frijol en Cuba." Agronomía Mesoamericana 10, no. 1 (2015): 55. http://dx.doi.org/10.15517/am.v10i1.19413.
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An experiment was carried out at the Lilliana Dimitrova Horticultural Research Institute in order to evaluate several advanced lines from the National Hybridization Program, and from the Nursery of Regional Resistance Sources of common bean, which were springled with Xanthomonas campestris (Xcp 530) – a highly aggressive bacterial strain. Fifteen varieties with intermediate resistance to the bacteria were selected. The CUT54, XAN 280, and 9356-26 lines were outstanding, showing better results than the control BAT 93.
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Abdulrazzaq, Najiba, Kashif Bin Naeem, Abdalla Alhajiri, et al. "Multiple Organ Dysfunction Reduces In-Hospital Survival in COVID-19 Patients." International Journal of Innovative Research in Medical Science 5, no. 09 (2020): 389–94. http://dx.doi.org/10.23958/ijirms/vol05-i09/951.
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Background: Although primarily a respiratory illness, COVID-19 involves multiple organs when the disease is severe or critical. Hence, we conducted this study to evaluate the incidence of multiple organ dysfunction in COVID-19 patients and its implications on survival. Methods: A retrospective analysis of laboratory-confirmed COVID-19 patients presenting to our center in Dubai, UAE between April 2020 and July 2020. Data was collected from the electronic medical records and analyzed to evaluate multiple organ damage observed during hospital admission. Findings: Five-hundred patients were studied. Overall mean age was 49.5 years (range 13-94), 76% males, 33% diabetics, 31% hypertensives. 97/500 (19.4%) had evidence of single organ damage; 37/500 (7.4%) had two organ damage; and 105/500 (21%) had more than two organ damage. Acute respiratory distress syndrome was the most prevalent organ damage,153/500 (30.6%); followed by acute cardiac injury, 120/500 (24%); acute kidney injury 107/500 (21.4%); acute liver injury 96/500 (19.2%); septic shock 93/500 (18.6%); disseminated intravascular coagulation 27/500 (5.4%), and heart failure 17/500 (3.4%). We found that in-hospital survival reduced as the number of organs involved increased; only 20% patients survived who had more than 2 organ damage. Also, the chances of survival reduced considerably once other organs were involved in addition to the acute respiratory distress syndrome (91.6% survival in ARDS alone vs. 28.6% survival in ARDS with acute kidney injury vs. 10.4% survival in ARDS with shock/acute cardiac injury/acute kidney injury). Conclusion: Multiple organ dysfunction is common in COVID-19 as 21% had evidence of more than two organ damage in our study. The survival in COVID-19 reduces significantly once multiple organs are involved. Early monitoring and recognition of multiple organ dysfunction is necessary to prevent adverse outcomes and improve survival.
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Chupong, Pudsadee, Pijan Jornsanoh, Karuna Tuchinda, and Anantawit Tuchinda. "Improvement Corrosion Resistance of Gray Cast Iron Grade FC220 on Chromizing Process by Separate Cr Powder and NH4Cl Powder System." Applied Mechanics and Materials 799-800 (October 2015): 397–401. http://dx.doi.org/10.4028/www.scientific.net/amm.799-800.397.
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A new configuration of chromizing process was developed by separating Cr powder from NH4Cl. FC220 gray cast iron specimens were chromized in this new experimental setup at 450, 550, 650,750, 850 and 950°C during 13 hours in order to study the possibility of chromizing at “low” temperature. The chromized specimens were examined using Scanning Electron Microscopy (SEM), macro-hardness, micro-hardness, compression test and salt spray test. The results shows that the specimen chromized at 650°C gives the best compromise between the corrosion resistance and the hardness of the FC220 with 1.73 ڌm of thickness of the chromized layer. However, after 13 hours of the process, the hardness of the FC220 specimens decreased considerably from 93 HRB to 64.2 HRB (31%).
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Fanning, P., and L. Hollaway. "A case study in the design and analysis for a 5.0 m deployable composite antenna." Composites Engineering 3, no. 11 (1993): 1007–23. http://dx.doi.org/10.1016/0961-9526(93)90017-e.
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Santos, Jucélia Stadinicki dos, Alice Fernandes Alfieri, José Paulo Gagliardi Leite, Irene Skraba, and Amauri Alcindo Alfieri. "Molecular epidemiology of the human group A rotavirus in the Paraná State, Brazil." Brazilian Archives of Biology and Technology 51, no. 2 (2008): 287–94. http://dx.doi.org/10.1590/s1516-89132008000200008.
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From January/2000 to December/2003, 550 diarrheic fecal samples from the children and adults were collected in several geographical regions of Paraná State, Brazil. The enzyme immunoassay showed 120 (21.8%) samples positive for the group A rotaviruses. One hundred and fourteen samples were genotyped by multiplex-nested-PCR assay. The highest frequency (77.5%) of the positive samples (n=93) was observed in the children under 5 years old. Rotavirus diarrhea was more frequent in the cold and dry seasons of the four evaluated years. The most frequent genotypes were: G1 (50.9%), G4 (9.6%), G9 (7.0%), G2 (1.7%), G3 (0.9%), P[ 8] (71.9%), and P[ 4] (3.5%). The P[ 8] G1 (46.5%) and P[ 8] G4 (9.6%) were the main combinations found to P and G genotypes. The mixed infections, characterized by the rotaviruses with more than one genotype G or P, and nontypeable rotavirus were observed in 8.8, 3.5, and 16.7% of the samples, respectively. The identification of the G9 genotype in the rotavirus strains tested along the four years of studies ratifies the emergency of this genotype also in Paraná State, South region of Brazil, as the worldwide.
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Chainok, Piyamas, Thanarat Khuntak, Supphadate Sujinnapram, et al. "Some properties of YBamCu1+mOy(m = 2, 3, 4, 5) superconductors." International Journal of Modern Physics B 29, no. 09 (2015): 1550060. http://dx.doi.org/10.1142/s0217979215500605.
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We synthesized the YBa m Cu 1+m O y superconductors; m = 2, 3, 4, 5 that were Y123 ( YBa 2 Cu 3 O 7-x), Y134 ( YBa 3 Cu 4 O 9-x), Y145 ( YBa 4 Cu 5 O 11-x), Y156 ( YBa 5 Cu 6 O 13-x), by solid state reaction with the Y 2 O 3, BaCO 3 and CuO as the beginning materials. The calcination temperature was 950°C and varied the sintering temperature to be 950°C and 980°C. The resistivity measurement by four-point-probe technique showed that the Tconset of Y123, Y134, Y145, Y156 were at 97, 93, 91, 85 K, respectively. The XRD and Rietveld full-profile analysis method were used and found that the crystal structure was in the orthorhombic with Pmmm space group with the ratio c/a were 3.0, 4.0, 5.0 and 6.0 for Y123, Y134, Y145 and Y156, respectively. The oxygen content was characterized by Iodometric titration. The ( Cu 3+/ Cu 2+ and Oxygen content) were (0.28, 6.83), (0.19, 8.81), (0.13, 10.79), (0.16, 12.92) of Y123, Y134, Y145, Y156, respectively. We also found that the increasing of sintering temperature has reduced the oxygen content and the critical temperature of all samples.
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Martin, Miguel, Ana Lluch, Amparo Ruiz, et al. "Randomized phase III study of adjuvant chemotherapy for high-risk, node-negative breast cancer (BC) comparing FAC with FAC followed by weekly paclitaxel: First efficacy analysis of the GEICAM/2003-02 trial." Journal of Clinical Oncology 30, no. 15_suppl (2012): 1001. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.1001.
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1001 Background: Adjuvant weekly paclitaxel (wP) sequential to anthracyclines improves the outcome of operable node-positive BC patients (pts) [Sparano NEJM 2008, Martin BCRT 2009]; however, most BC pts are currently node-negative at diagnosis. The role of wP in these pts is not well established yet. Methods: Pts aged 18-70, with T1-T3/N0 operable BC and at least one high-risk St Gallen 1998 criteria (size >2 cm, hormone-receptor [HR] negative, grade 2/3, age <35 years,) were eligible. HER2+ pts were allowed, after 792 entered the trial, the study was amended to exclude them. Pts were stratified by site, menopausal status, nodal status diagnostic method (sentinel-node biopsy versus lymphadenectomy) and HR status and randomized to receive FAC x6 (500/50/500 mg/m2 every 3w) or FAC x4→wP x8 (paclitaxel 100 mg/m2 weekly). The primary endpoint was DFS. The trial was designed to detect an absolute 5-y DFS increase of 5% (80% FAC, 85% FAC→wP); a sample size of 1812 evaluable patients (906 per arm) was required to detect this difference (α=0.05, β= 80%). Assuming a drop-out rate of 6%, 1929 pts were required. The first analysis of DFS was planned when a median follow-up of 5 years was reached. Results: Between September 2003 and October 2008, 1925 pts (FAC 974, FAC→wP 951) were randomized. Patient characteristics were well balanced between arms, median age was 50, 73% of pts were HR positive and 9% HER2 positive. 97% of pts with FAC and 85% of pts with FAC→wP completed all treatment as planned. The median dose intensity was 98% with FACx6, 99% with FACx4 and 98% with wP. The most frequent grade 3-4 toxicities (>3% in either arm) with FAC vs FAC→wP were neutropenia (25% vs 22%) with 4% vs 3% of febrile neutropenia, fatigue (3% vs 8%), sensory neuropathy (0 vs 5%), and vomiting (4% in each arm). After a median follow-up of 5.3 years, the proportion of patients disease free is 93% and 90% with FAC→wP and FAC (HR for relapse 0.732, 95% CI: 0.542 to 0.990; log-rank p-value=0.0423). Conclusions: For pts with high-risk node-negative BC, adjuvant FAC→wP was associated with a small but significant improvement in DFS compared with FAC, with manageable toxicity.
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Doreswamy, Ramesh, Mohini Saini, Devendra Swarup, et al. "Interferon Alpha Characterization and Its Comparative Expression in PBM Cells of Capra hircus and Antelope cervicapra Cultured in the Presence of TLR9 Agonist." Molecular Biology International 2010 (June 3, 2010): 1–6. http://dx.doi.org/10.4061/2010/573426.
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TLR9 plays pivotal role in innate immune responses through upregulation of costimulatory molecules and induction of proinflammatory cytokines like type I interferons including interferon alpha (IFNA). The present study characterized IFNA cDNA and predicted protein sequences in goat and black buck. Response of the PBM cells to TLR9 agonist CpG ODN C and Phorbol Myristate Acetate (PMA) was evaluated by realtime PCR. IFNA coding sequences were amplified from leukocyte cDNA and cloned in pGEMT-easy vector for nucleotide sequencing. Sequence analysis revealed 570 bp, IFNA ORF encoding 189 amino acids in goat and black buck. Black buck and goat IFNA has 92.1% to 94.7% and 93% to 95.6% similarity at nucleotide level, 86.3% to 89.5% and 70.9% to 91.6% identity at amino acid level with other ruminants, respectively. Nonsynonymous substitutions exceeding synonymous substitutions indicated IFNA evolved through positive selection among ruminants. In spite of lower total leukocyte count, the innate immune cells like monocytes and neutrophils were more in black buck compared to goat. In addition, CpG ODN C-stimulated PBM cells revealed raised IFNA transcript in black buck than goat. These findings indicate sturdy genetically governed immune system in wild antelope black buck compared to domestic ruminant goat.
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Mirmiran, Hajipour, and Azizi. "Iodized Salt Consumption Maintains Euthyroidism in Iodine-Deficient Hypothyroid Subjects." International Journal for Vitamin and Nutrition Research 73, no. 3 (2003): 187–91. http://dx.doi.org/10.1024/0300-9831.73.3.187.
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Following previous reports of impaired physical and intellectual growth, hearing deficit, hypothyroidism, and hyperendemic goiter in Kiga, and the administration of iodized oil injection, this study was conducted to evaluate whether or not the effect of the injection could be sustained by iodized salt supplementation. In 1989, one mL of iodized oil solution containing 480 mg of iodine was injected in 198 schoolchildren aged 8 to 14 years. Four years later, in 1993, iodized salt consumption was begun and has since been continued. Serum thyroid hormones, RT3 uptake and thyroid-stimulating hormone (TSH) were measured before, and three, four, and six years after intervention (1989, 1992, 1993, and 1995). Assessment of urinary iodine was performed by the Foss method at the same intervals mentioned above. Prior to the injection, 94% had grade 2 goiters; four years after injection, 26% and 41% had grades 2 and 1 respectively, and 30% had no goiter (p < 0.001). Two years after the introduction of iodized salt consumption, 5 and 39% had grades 2 and 1 goiter, and 56% were not goiterous. Urinary iodine was 11.4 ± 19.8 mug/L before intervention, and was increased to 93 ± 66 and 92 ± 34 mug/L, three and four years, respectively, after intervention. Two years after iodized salt consumption it was 161 ± 34 mug/L. Mean serum T4 was 5.0 ± 2.0, 9.6 ± 2.0, 9.6 ± 2.0 and 9.2 ± 1.5 mug/dL; serum TSH was 20.3 ± 22.8, 2.1 ± 1.9, 2.5 ± 1.6 and 2.9 ± 1.7 mU/L; before and three, four, and six years after the beginning of the study. All children were euthyroid after three, four, and six years of study. Findings show the benefits of iodized oil administration in decreasing goiter size and in reversing abnormal thyroid function. These effects are sustained by iodized salt consumption in schoolchildren who had been previously hypothyroid due to iodine deficiency.
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Le Bel, Sébastien, Michel Salas, and Dominique Dulieu. "Typologie des élevages de cerfs en Nouvelle-Calédonie et impact d'un suivi des performances d'abattage." Revue d’élevage et de médecine vétérinaire des pays tropicaux 50, no. 4 (1997): 335–42. http://dx.doi.org/10.19182/remvt.9565.
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Une typologie des élevages de cerfs a été réalisée grâce à la méthode graphique de Bertin. Quatre grands types d'élevage qui se différenciaient essentiellement selon la superficie des pâturages, le chargement moyen et l'intensification des pratiques d'élevage ont pu être distingués. La campagne d'abattage de 1994 totalisait 1 053 têtes dont 927 ont été concernées par le suivi. Les cerfs abattus étaient des mâles entiers (93 %). Trente-cinq pour cent de l'effectif étaient âgés entre 1 et 2 ans et 48 % avaient plus de 2 ans. Le pourcentage de carcasses déclassées était de 1,6 % chez les éleveurs ayant opté pour la pesée comme outil de tri ; chez les autres éleveurs, il était sept fois plus important (12 % ; différence significative p < 0,001). Le poids vif (PV) moyen des cerfs abattus (n = 510) était de 49,0 + ou - 0,6 kg, le poids carcasse (PC) moyen (n = 927) à chaud après égouttage était de 28,4 + ou - 0,3 kg et le rendement à chaud (RD) moyen était de 56,8 + ou - 0,3 %. Des analyses de la variance conduites sur les variables PV, PC et RD montrent que les facteurs types d'élevage, âge et saison d'abattage avaient un effet significatif. L'effet type d'élevage ne permet pas de discriminer un type d'exploitation plus performant. Les élevages extensifs (type 4) avaient des performances plus faibles par manque de finition de leurs animaux. De 1 à 2 ans, le PC a augmenté de 6 kg (25 kg/31 kg) mais le RD a diminué de 2 %, de 58 à 56 %. La meilleure saison d'abattage était la saison fraîche avec des carcasses de 30 kg et un rendement de 57 %. Une équation de régression significative (p < 0,001) permet de prédire le PC en fonction de PV [PC(kg) = 0,5 PV(kg) + 3,4]. Vis-à-vis des autres pays éleveurs de cerfs rusa, les performances d'abattage obtenues en Nouvelle-Calédonie étaient moins bonnes. Cette différence de niveau de performance est à rattacher au mode d'élevage plus extensif du cerf rusa en Nouvelle-Calédonie. L'amélioration du niveau de production semble liée à une meilleure stratégie alimentaire pendant la saison sèche et à la finition des jeunes mâles abattus avant deux ans.
Dissertations / Theses on the topic "580.956 93"
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Stodieck, Sophia Katharina [Verfasser], Siegrid [Akademischer Betreuer] [Gutachter] Loewel, Tim [Gutachter] Gollisch, and Oliver M. [Gutachter] Schlueter. "The role of postsynaptic density (PSD) proteins PSD-95 and PSD-93 for mouse visual cortical plasticity and vision / Sophia Katharina Stodieck ; Gutachter: Siegrid Loewel, Tim Gollisch, Oliver M. Schlueter ; Betreuer: Siegrid Loewel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1140641999/34.
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Stodieck, Sophia Katharina. "The role of postsynaptic density (PSD) proteins PSD-95 and PSD-93 for mouse visual cortical plasticity and vision." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0023-3F15-A.
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Duda, Joana-Kristin. "The role of DLG-MAGUKs in mediating signaling specificity at the postsynaptic density." Doctoral thesis, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E570-E.
Full textBook chapters on the topic "580.956 93"
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Su, Chunming, Robert W. Puls, Thomas A. Krug, et al. "Long-Term Performance Evaluation of Groundwater Chlorinated Solvents Remediation Using Nanoscale Emulsified Zerovalent Iron at a Superfund Site." In Waste Management. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1210-4.ch061.
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This chapter addresses a case study of long-term assessment of a field application of environmental nanotechnology. Dense Non-Aqueous Phase Liquid (DNAPL) contaminants such as Tetrachloroethene (PCE) and Trichloroethene (TCE) are a type of recalcitrant compounds commonly found at contaminated sites. Recent research has focused on their remediation using environmental nanotechnology in which nanomaterials such as nanoscale Emulsified Zerovalent Iron (EZVI) are added to the subsurface environment to enhance contaminant degradation. Such nanoremediation approach may be mostly applicable to the source zone where the contaminant mass is the greatest and source removal is a critical step in controlling the further spreading of the groundwater plume. Compared to micro-scale and granular counterparts, NZVI exhibits greater degradation rates due to its greater surface area and reactivity from its faster corrosion. While NZVI shows promise in both laboratory and field tests, limited information is available about the long-term effectiveness of nanoremediation because previous field tests are mostly less than two years. Here an update is provided for a six-year performance evaluation of EZVI for treating PCE and its daughter products at a Superfund site at Parris Island, South Carolina, USA. The field test consisted of two side-by-side treatment plots to remedy a shallow PCE source zone (less than 6 m below ground surface) using pneumatic injection and direct injection, separately in October 2006. For the pneumatic injections, a two-step injection procedure was used. First, the formation was fluidized by the injection of nitrogen gas alone, followed by injection of the EZVI with nitrogen gas as the carrier. In the pneumatic injection plot, 2,180 liters of EZVI containing 225 kg of iron (Toda RNIP-10DS), 856 kg of corn oil, and 22.5 kg of surfactant were injected to remedy an estimated 38 kg of chlorinated volatile compounds (CVOC)s. Direct injections were performed using a direct push rig. In the direct injection plot, 572 liters of EZVI were injected to treat an estimated 0.155 kg of CVOCs. Visual inspection of collected soil cores before and after EZVI injections shows that the travel distance of EZVI was dependent on the method of delivery with pneumatic injection achieving a greater distance of 2.1 m than did direct injection reaching a distance of 0.89 m. Significant decreases in PCE and TCE concentrations were observed in downgradient wells with corresponding increases in degradation products including significant increases in ethene. In the pneumatic injection plot, there were significant reductions in the downgradient groundwater mass flux values for chlorinated ethenes (>58%) and a significant increase in the mass flux of ethene (628%). There were significant reductions in total CVOCs mass (78%), which was less than an estimated 86% decrease in total CVOCs made at 2.5 years due to variations in soil cores collected for CVOCs extraction and determination; an estimated reduction of 23% (vs.63% at 2.5 years) in the sorbed and dissolved phases and 95% (vs. 93% at 2.5 years) reduction in the PCE DNAPL mass. Significant increases in dissolved sulfide, volatile fatty acids (VFA), and total organic carbon (TOC) were observed and dissolved sulfate and pH decreased in many monitoring wells. The apparent effective destruction of CVOC was accomplished by a combination of abiotic dechlorination by nanoiron and biological reductive dechlorination stimulated by the oil in the emulsion. No adverse effects of EZVI were observed for the microbes. In contrast, populations of dehalococcoides showed an increase up to 10,000 fold after EZVI injection. The dechlorination reactions were sustained for the six-year period from a single EZVI delivery. Repeated EZVI injections four to six years apart may be cost-effective to more completely remove the source zone contaminant mass. Overall, the advantages of the EZVI technology include an effective “one-two punch” of rapid abiotic dechlorination followed by a sustained biodegradation; contaminants are destroyed rather than transferred to another medium; ability to treat both DNAPL source zones and dissolved-phase contaminants to contain plume migration; ability to deliver reactants to targeted zones not readily accessible by conventional permeable reactive barriers; and potential for lower overall costs relative to alternative technologies such as groundwater pump-and-treat with high operation and maintenance costs or thermal technologies with high capital costs. The main limitations of the EZVI technology are difficulty in effectively distributing the viscous EZVI to all areas impacted with DNAPL; potential decrease in hydraulic conductivity due to iron corrosion products buildup or biofouling; potential to adversely impact secondary groundwater quality through mobilization of metals and production of sulfides or methane; injection of EZVI may displace DNAPL away from the injection point; and repeated injections may be required to completely destroy the contaminants.
Conference papers on the topic "580.956 93"
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Selverian, J. H., Dave A. ONeil, and Shinhoo Kang. "Performance Testing and Strength Prediction of Ceramic-to-Metal Joints." In ASME 1993 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/93-gt-412.
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Brazed joints were made between silicon nitride and Ni-based and Fe-based super alloys. Room temperature shear (torsion) strengths ranged from 75–242 MPa for Si3N4-to-Incoloy 909 joints and from 30–127 MPa for the Si3N4-to-Inconel 718 joints. At 500 °C the joint strength was 120 MPa while at 650°C and 950°C the joints strengths were less than 20 MPa. These low strengths at 650°C and 950°C were attributed to a reduction in the shrink-fit and to low braze strength at these high temperatures. Finite element analysis (FEA) and a probabilistic failure theory (CARES) were used to predict the joint strengths. The predicted joint strengths agreed well with measured joint strengths in torsional loading at 20°C. Torsion tests were also performed at 650°C. Aspects of the material systems, residual stresses, mechanical behavior, and strength predictions are presented. Two new braze alloys based on the Au-Ni-Cr-Fe system were used to overcome the poor high temperature strength. Joints made with these brazes had good strength (85 MPa and 35 N-m) at 650°C.
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Amrani, D. L., та M. W. Mosesson. "THE CONTRIBUTION OF FIBRINOGEN Aα, γn, AND γ’ CHAINS IN SUPPORTING ADP-INDUCED PLATELET AGGREGATION". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643637.
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Human plasma fibrinogen (ϕ) is heterogeneous with respect to its γ’ chain population (γn 93%; γ’ 7%) which differ in that C-terminal residues 407-411 of γn are replaced in γ’ by a unique 20 amino acid sequence. DEAE-cellulose chromatography yields two major $ peaks (peak 1 and peak 2 ϕ). Peak 1 ϕ molecules each contain two γn chains whereas peak 2 ϕ molecules are heterodimeric with respect to γn and γ’ chains. Using washed human platelets (PL), we confirmed that the number of peak 2 ϕ molecules binding to PL in the presence of ADP is about half the number of peak 1 ϕ molecules (18,962 ± 2,298 vs. 44,366 ± 16,096 molecules per PL) although Kds were similar − 0.20 µM and 0.26 µM, respectively. We also confirmed that isolated S-carboxymethyl (SCM)γn chains supported PL aggregation well (85% of peak 1 ϕ @ 0.94 mg/ml). In contrast to γn chains, SCM γ’ chains supported aggregation poorly (12% of peak 1 ϕ), and a 50:50 mixture of γn and γ’ supported aggregation to only 65%. Nevertheless, we found that peak 2 ϕ (n=15) supported aggregation well in the presence of ADP (5-20 mM) to an extent that was ≥ 93% of that of peak 1 ϕ (n=8). Since the C-terminal region of the Aγ chain has been shown to play a role in ϕ-PL interactions, we evaluated whether this region in peak 2 ϕ molecules was particularly important for maintaining its ability to support PL aggregation. Peak 2 ϕ from which C-terminal Aγ chain fragments had been removed by digestion with plasmin from >96% to 93 or 90% coagulability, showed decreased PL aggregation potential (71% and 54%, respectively) compared to comparably digested peak 1 ϕ (90% coagulable; 90% aggregation). In contrast to plasmin digested peak 2 ϕ, an unchromatographed plasma ϕ fraction (I-9) lacking C-terminal regions of Aγ chains but rich in γn chains, supported PL aggregation to the same extent as did intact peak 2 ϕ. These findings indicate that ϕ molecules containing Yγn chains can approach the aggregation potential of ϕ molecules containing 100% γn only if intact Aγ chains are also present.
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Hamdan, Abeer, and Manar Abdel-Rahman. "Child Disciplinary Practices in relation to Household Head Education and beliefs in Five Middle East and North African (MENA) countries: Cross Sectional study-Further analysis of Multiple Indicator Cluster survey data." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0168.
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Introduction:Internationally, eight out of ten children are exposed to violent discipline by their caregivers. To reduce the prevalence of violent discipline against children, we should understand the social and economic factors that affect the choice of disciplinary methods. Despite the high prevalence of violent discipline in the Middle East and North African (MENA) region, only a few studies explored disciplinary methods in this region. Aim: This study aims to determine the prevalence of positive and violent disciplinary practices in five selected MENA countries and assess their association with household head education and beliefs of physical punishment. Methods: This is a cross-sectional study design based on available secondary data from the Multiple Indicator Cluster Survey on its fourth round (MICS-4). A child was selected randomly from the household, and the Parent-Child Conflict Scale (CTSPC) tool was used to report disciplinary methods the child encountered during the last month period preceding the survey. Univariate and multivariable logistic regression were used to investigate the association between disciplinary practices with household head education and respondent's beliefs of physical punishment. The analysis was conducted using pooled data from all selected surveys and also for individual countries. Result: The overall prevalence of positive discipline was only 15% (95% CI: 14.4-15.8), in the five countries, while the prevalence of violent discipline was 80% (95% CI: 79.0 -80.5). The prevalence of positive discipline was highest in Qatar (40%; 95% CI: 35.0-44.4) and lowest in Tunisia (5%; 95% CI: 4.3-5.9) while the prevalence of violent discipline was highest in Tunisia (93%; 95% CI: 92.1-94.1), and lowest in Qatar (50%; 95% CI: 44.7-55.0). Overall, the household head education was not significantly associated with either positive or violent discipline after adjusting for covariates. However, respondents believe of disciplinary methods was significantly associated with both positive and violent discipline (OR=5.88; 95% CI: 4.97-6.96) and (OR=6.27; 95% CI: 5.40-7.28), respectively. Conclusion: High rates of violent discipline in the MENA region might indicate an increase in mental, behavioral, and social problems and disorders in our future generation. Rapid action is needed to reduce the worsening of violent discipline, and it is consequences. There is a need for educational programs for caregivers to teach them alternative non-violent methods of discipline. Besides, these numbers should inform policymakers about the importance of the existence and the implementations of laws, policies, and regulations to protect children from all forms of violence to protect our future youths and ensure their health and wellbeing.
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Ishizuka, Takao, Yasushi Muto, and Masanori Aritomi. "Design and Test Plan of the Supercritical CO2 Compressor Test Loop." In 16th International Conference on Nuclear Engineering. ASMEDC, 2008. http://dx.doi.org/10.1115/icone16-48335.
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Supercritical carbon dioxide (CO2) gas turbine systems can generate power at a high cycle thermal efficiency, even at modest temperatures of 500–550°C. That high thermal efficiency is attributed to a markedly reduced compressor work in the vicinity of critical point. In addition, the reaction between sodium (Na) and CO2 is milder than that between H2O and Na. Consequently, a more reliable and economically advantageous power generation system can be created by coupling with a Na-cooled fast breeder reactor. In a supercritical CO2 turbine system, a partial cooling cycle is employed to compensate a difference in heat capacity for the high-temperature — low-pressure side and low-temperature — high-pressure side of the recuperators to achieve high cycle thermal efficiency. In our previous work, a conceptual design of the system was produced for conditions of reactor thermal power of 600 MW, turbine inlet condition of 20 MPa/527°C, recuperators 1 and 2 effectiveness of 98%/95%, Intermediate Heat Exchanger (IHX) pressure loss of 8.65%, a turbine adiabatic efficiency of 93%, and a compressor adiabatic efficiency of 88%. Results revealed that high cycle thermal efficiency of 43% can be achieved. In this cycle, three different compressors, i.e., a low-pressure compressor, a high-pressure compressor, and a bypass compressor are included. In the compressor regime, the values of properties such as specific heat and density vary sharply and nonlinearly, dependent upon the pressure and temperature. Therefore, the influences of such property changes on compressor design should be clarified. To obtain experimental data for the compressor performance in the field near the critical point, a supercritical CO2 compressor test project was started at the Tokyo Institute of Technology on June 2007 with funding from MEXT, Japan. In this project, a small centrifugal CO2 compressor will be fabricated and tested. During fiscal year (FY) 2007, test loop components will be fabricated. During FY 2008, the test compressor will be fabricated and installed into the test loop. In FY 2009, tests will be conducted. This paper introduces the concept of a test loop and component designs for the cooler, heater, and control valves. A computer simulation program of static operation was developed based on detailed designs of components and a preliminary design of the compressor. The test operation regime is drawn for the test parameters.
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Musso, R., A. Longo, M. L. Morrone, R. R. Cacciola, A. Lombardo, and R. Giustolisi. "EVIDENCE FOR AN INCREASED FIBRONECTIN SYNTHESIS IN VASCULAR ENDOTHELIUM OF DIABETIC SUBJECTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643096.
Full textAbstract:
Increased plasma levels of Fibronectin (Fn),a well known adesive glycoprotein synthesized in vessel endothelial cells, have been reported in diabetes mellitus (DM). Previously, we provided evidence that in type II DM an elevated storage of Fn is present in endothelial cells. We here report that in diabetic subjects an abnormal synthesis of Fn in endothelial cells could also occur. To verify this hypothesis, in 15 patients affected by type II DM, age ranging 36-59, of both sex, without overt clinical vascular complications and in glycometabolic compensation (Hb Alc 8.9 ± 1.5) we evaluated before and after venostasis repeated at several times 30, 60, 90,180 and 210 min the Fn plasma levels. Five healthy volunteers, age and sex comparaf-h ble, were utilized as normal controls. The venostasis were performed at forearm pressure of 10 mmHg over diastolic x 20 min and blood samples were collected from the same vein at the intervals above indicated. Plasma Fn was evaluated by ELISA immuno-enzymatic tecnique using a commercial kit (Biochemia, Milan). The diabetic patients showed after the first venostasis a significant (p<0.001) increase of Fn (317 ± 103μg/ml) versus the baseline values (225±79 μg/ml)while normal controls did not (before 103 ± 37, after 139±61). Such an increase was also seen in EM after the second venostasis ( 298 ±91 μg/ml, vs 128±58 in controls), whereas at third venostasis plasma Fn levels retoumed to the values comparable to the basal ones both in diabetics (245 ±. 88 μg/ml) and in controls (93±41 μg/ml). After 90 min pause by performing the fourth venostasis we observed in diabetics a further increase pf Fn (298±131μg/ml) which reached:again the values noted after the first. No change, on the contrary,was found in the normal group (95±21). In the last venostasis,carried out 30min from the fourth, the plasna Fn lasted significantly (p<0.001.) increased in diabetics (281±107 μg/ml) respect to normal controls (102±19 μg/ml).Our data, therefore, would suggest that in vascular endothelium cf type II DM an increased synthesis of Fn occurs as well.