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1

Baran, Yakup, Trevor W. Hambley, Geoffrey A. Lawrance, and Eric N. Wilkes. "Syntheses and Comparative Base Hydrolysis Reactions of Chlorocobalt(III) Complexes of Pendant-Arm Macrocyclic Polyamines and Polyamino Acids." Australian Journal of Chemistry 50, no. 9 (1997): 883. http://dx.doi.org/10.1071/c96196.

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Chlorocobalt(III) complexes of the pendant-arm macrocycles 1,4,8,12-tetraazacyclopentadecane-10-carboxylate (2) and 1,5,9,13-tetraazabicyclo[11.2.2]heptadecane-7-carboxylate (4) have been prepared to complement the known complexes of 10-methyl-1,4,8,12-tetraazacyclopentadecan-10-amine (1) and 7-methyl-1,5,9,13-tetraazabicyclo[11.2.2]heptadecan-7-amine (3). The pairs (1),(3) and (2),(4) differ in replacement of pendant amine and methyl groups in the former pair by a pendant carboxylate group and hydrogen in the latter pair. The macromonocyclic ligands (1) and (2) form cis-chlorocobalt(III) complexes whereas the macrobicyclic ligands (3) and (4) (which contain an additional –CH2–CH2– ‘strap’ linking two amines) form trans-chlorocobalt(III) complexes, defined in terms of location of the pendant donor and the chloride donor. Chloride base hydrolysis kinetics varies with ligand {cis-[Co(1)Cl]2+, kOH 6700 dm3 mol-1 s-1 ; cis-[Co(2)Cl] +, kOH 1800 dm3 mol-1 s-1;trans-[Co(3)Cl]2+, kOH 3450 dm3 mol-1 s-1; trans-[Co(4)Cl]+, kOH 2250 dm3 mol-1 s-1 at 25°C}. Variations in rate constant are tied mainly to variations in activation enthalpy. Chloride hydrolyses occur with retention of configuration, but slow following isomerization can lead to products such as trans-[Co(2)(OH2)] (ClO4)2.2H2O, which crystallizes in the monoclinic space group P21/c, a 9·581(2), b 16·214(2), c 14·350(2) Å and β 94·66(1)°. The pendant carboxylate group and two adjacent secondary amines necessarily occupy an octahedral face, with the water molecule bound trans to the pendant carboxylate. The four Co–N distances range from 1·981(2) to 2·22(3) Å, and along with carboxylate Co–O (1·882(3) Å) and water Co-O (1·934(2) Å) distances are similar to usual distances in cobalt(III) complexes.
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2

Fisher, A. "Report of the obstetric faculty clinic of the Imperial Moscow University for 1890." Journal of obstetrics and women's diseases 6, no. 3 (2020): 309–10. http://dx.doi.org/10.17816/jowd63309-310.

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During the reporting year, 623 pregnant women and women in labor were admitted to the clinic; of these, 598 were resolved in the clinic, and 25 dropped out before giving birth; from May 1 to September 19, there was no delivery of women in labor. There were 138 primiparas (23.1%), voniparas 142 (23.7%), and many 318 (53.2%); primiparas over 30 years old met 20, including one 47 years old. There were 584 single genera and 14 twins. Urgent 506, premature 73, miscarriages 19. Presentation (except for 11 early miscarriages): headache 571 (95.0%), shoulder 3 (0.5%); of the head: occipital 558, parietal 2, ear 1, facial 5, not recognized (street delivery, etc.) 5. A narrow pelvis was observed in 54 cases (9%).
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3

Debbage, Keith G. "Transport and Tourism; S. Page, Addison Wesley Longman, Harlow 1999, 350 pages, ISBN 0-582-32025-9." Journal of Transport Geography 7, no. 3 (1999): 229–30. http://dx.doi.org/10.1016/s0966-6923(99)00009-5.

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4

Lang, Peter, Heiko-Manuel Teltschik, Patrick Schlegel, et al. "Use of a Fc-Optimized CD19 Antibody for Treatment of MRD in Pediatric Patients with B-Lineage Acute Lymphoblastic Leukemia." Blood 120, no. 21 (2012): 581. http://dx.doi.org/10.1182/blood.v120.21.581.581.

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Abstract Abstract 581 Primary refractory or relapsed B-lineage acute lymphoblastic leukemia can be successfully treated by allogeneic stem cell transplantation (SCT). However, relapse remains still a major risk and will be significantly influenced by residual disease prior to or after SCT. In addition to standard chemotherapy, immunotherapeutic approaches are assumed to be able to reduce or clear persistent minimal disease. Here we investigated an Fc-optimized chimerized CD19 antibody on a compassionate use basis in pediatric patients at very high risk prior to and after allogeneic, HLA matched (n=2) or mismatched (n=9) first or subsequent SCT. Through its improved capability to recruit FcγRIIIA bearing effector cells, this mAb mediates enhanced ADCC by NK cells but no complement lysis. 11 patients with B-lineage ALL (CR2 with MRD>10−4, n=3; ≥CR3, n=4; active disease, n=4; 8/11 had previous SCTs) received a mean number of 10 (range 1–30) infusions with an anti-CD19 mAb (4G7SDIE) over 6 hours weekly or every second week posttransplant. In 7 patients, additional infusions were given prior to transplant. Dosages ranged from 5 to 50 mg/m2. The infusions were well tolerated without any severe side effects; only fever or headache was observed in a few patients (n=4). Minimal residual disease (MRD) or overt relapse (>50% blasts) was detectable in bone marrow aspirates prior to therapeutic mAb administration in 5/11 and 2/11 patients, respectively. Prophylactic CD19mAb infusions were given posttransplant without measurable MRD levels in 4/11 patients and in another 2 patients (who did not respond to pretransplant CD19mAb because of overt relapse but reached MRD negativity after SCT) due to an extremely high relapse risk. In 4 out of 5 patients with detectable MRD, leukemic load was reduced for at least 1 log or eradicated by the mAb. 2 out of those patients relapsed, 2 other patients are in molecular remission since 270 and 350 days. Both patients with overt relapse did not respond. 2/6 patients with prophylactic mAb infusions relapsed after 121 and 186 days, 4 other patients remain in molecular remission since 52–180 days. Taken together, a response could be documented in 4/7 patients; a total of 6/11 patients are in molecular remission (median follow up 157 days). Concomitant in vitro investigations showed that NK cells of the patients exerted insufficient lysis of primary B-lineage ALL blasts (mean specific lysis: 4,00%). However, lysis could be significantly increased by adding autologous patient serum taken after antibody treatment (mean specific lysis: 20,33 %, p = 0.0001, student's t-test) or by adding 1 μg/ml 4G7SDIE (mean specific lysis: 34.84 %, p < 0.0001). Activity of patient NK cells was similar to NK cells of healthy donors. ADCC relevant serum titers of biologically active CD19mAb were detectable up to 7 days after antibody infusion. In conclusion, promising antileukemic effects have been observed in vitro and in vivo in this pilot study and a further clinical trial has to address the question whether this approach will be able to reduce relapse rates. Disclosures: No relevant conflicts of interest to declare.
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5

Clark, Peter. "Contemporary Catholic Health Care Ethics. By David F. Kelly. Georgetown University Press2004. Pp. 352. $32.50. ISBN: 9-581-05030-2." Journal of Law and Religion 21, no. 1 (2006): 201–4. http://dx.doi.org/10.1017/s0748081400002927.

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6

Rojo, Marc Bertran, Elise Beck, and Céline Lutoff. "The street as an area of human exposure in an earthquake aftermath: the case of Lorca, Spain, 2011." Natural Hazards and Earth System Sciences 17, no. 4 (2017): 581–94. http://dx.doi.org/10.5194/nhess-17-581-2017.

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Abstract. The earthquake which struck the city of Lorca, Spain, on 11 May 2011 killed 9 people, injured over 300 and caused considerable damage, including one collapsed building. Streets near buildings were the main danger areas for people. This article proposes an dynamic ad hoc spatio-temporal method for studying individual evacuation after an earthquake. Its application to the Lorca case shows the spatial and temporal variability of individual exposure levels in the street during the hours following the shock. As yet little studied, human exposure deserves more attention, particularly in zones of moderate seismicity like the Euro-Mediterranean area. The results of this study could be helpful for enhancing the evacuation planning after an earthquake, stressing the specific dangers in the street.
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7

Ge, Q., Z. Hao, J. Zheng, and X. Shao. "Temperature changes over the past 2000 yr in China and comparison with the Northern Hemisphere." Climate of the Past 9, no. 3 (2013): 1153–60. http://dx.doi.org/10.5194/cp-9-1153-2013.

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Abstract. We use principal component regression and partial least squares regression to separately reconstruct a composite series of temperature variations in China, and associated uncertainties, at a decadal resolution over the past 2000 yr. The reconstruction is developed using proxy temperature data with relatively high confidence levels from five regions across China, and using a temperature series from observations by the Chinese Meteorological Administration, covering the period from 1871 to 2000. Relative to the 1851–1950 climatology, our two reconstructions show four warm intervals during AD 1–AD 200, AD 551–AD 760, AD 951–AD 1320, and after AD 1921, and four cold intervals during AD 201–AD 350, AD 441–AD 530, AD 781–AD 950, and AD 1321–AD 1920. The temperatures during AD 981–AD 1100 and AD 1201–AD 1270 are comparable to those of the Present Warm Period, but have an uncertainty of ±0.28 °C to ±0.42 °C at the 95% confidence interval. Temperature variations over China are typically in phase with those of the Northern Hemisphere (NH) after 1000, a period which covers the Medieval Climate Anomaly, the Little Ice Age, and the Present Warm Period. In contrast, a warm period in China during AD 541–AD 740 is not obviously seen in the NH.
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8

TURNER, JOHN. "The British Conservative Party in the Twentieth Century: from Beginning to End?" Contemporary European History 8, no. 2 (1999): 275–87. http://dx.doi.org/10.1017/s0960777399002052.

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Stuart Ball, The Conservative Party since 1945 (Manchester: Manchester University Press, 1998), 205 pp., £40.00, ISBN 0-7190-4012-4.John Charmley, A History of Conservative Politics, 1900–1996 (London: Macmillan, 1996), 283 pp., £16.99, ISBN 0-333-56293-3.Alan Clark, The Tories: Conservatives and the Nation State 1922–1997 (London: Weidenfeld & Nicolson, 1998), 493 pp., £20.00, ISBN 0-297-81849-X.N. J. Crowson, Facing Fascism: The Conservative Party and the European Dictators 1935–1940 (London: Routledge, 1997), 270 pp., £20.00, ISBN 0-415-15315-8.Brendan Evans and Andrew Taylor, From Salisbury to Major: Continuity and Change in Conservative Politics (Manchester: Manchester University Press, 1996), 288 pp., £14.99, ISBN 0-7190-4291-7.Steven Ludlam and Martin J. Smith, Contemporary British Conservatism (London: Macmillan, 1996), 322 pp., £14.99, ISBN 0-333-62949-3.Philip Norton (ed.), The Conservative Party (London: Prentice Hall, 1996), 264 pp., £15.95, ISBN 0-13-374653-4.John Ramsden, An Appetite for Power: A History of the Conservative Party since 1830 (London: HarperCollins, 1998), 562 pp., £24.99, ISBN 0-002-55686-3.John Ramsden, The Age of Churchill and Eden 1940–1957 (London: Longman, 1995), 350 pp., £57.50, ISBN 0-582-50463–5.John Ramsden, The Winds of Change: Macmillan to Heath 1957–1975 (London: Longman, 1996), 485 pp., £70.00, ISBN 0-582-27570-9.Anthony Seldon (ed.), How Tory Governments Fall (London: Fontana, 1996), 510 pp., £7.99, ISBN 0-00-686366-3.Anthony Seldon and Stuart Ball (eds.), Conservative Century: The Conservative Party since 1900 (Oxford: Oxford University Press, 1994), 842 pp., £20.00, ISBN 0-19-820238-5.Robert Self, The Austen Chamberlain Diary Letters: The Correspondence of Sir Austen Chamberlain with his sisters Hilda and Ida, 1916–1937 (Cambridge: Cambridge University Press for the Royal Historical Society, 1995), 548 pp., £40.00., ISBN 0-521-55157-9.
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9

Arnold, David. "Frank Lentricchia, Modernist Quartet (Cambridge: Cambridge University Press, 1994, £35, Pb £13.95). Pp. 305. ISBN 0 521 47004 8; 0 521 46975 9." Journal of American Studies 29, no. 3 (1995): 480. http://dx.doi.org/10.1017/s0021875800022647.

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10

Barbetti, Mike, Trevor Bird, George Dolezal, et al. "Radiocarbon Variations from Tasmanian Conifers: Results from Three Early Holocene Logs." Radiocarbon 37, no. 2 (1995): 361–69. http://dx.doi.org/10.1017/s0033822200030836.

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Dendrochronological studies are being carried out on two conifer species in the Stanley River area of western Tasmania. The chronology for Huon pine (Lagarostrobos franklinii), with living trees up to 1400 yr old, extends back to 571 bc. Living celery-top pine (Phyllocladus aspleniifolius) trees are up to 500 yr old. Apart from living or recently felled trees, sections have been taken from 350 subfossil logs preserved in floodplain sediments. They range in age from >38 ka to modern, with good coverage for the periods 9–3.5 ka and from 2.5 ka to the present. We report here on 14C measurements of decadal samples from three early Holocene logs, between 10 and 9 ka bp, providing short (ca. 300-yr) records of atmospheric 14C variations when plotted against ring numbers. The southern hemisphere data from Tasmania can be compared and wiggle-matched with published 14C calibration curves from German oak and pine. One set of measurements covers the period, ca. 9280–8990 cal bp, overlapping the link between the Hohenheim “Main 9” and middle Holocene master oak chronologies. The other sets of measurements from Tasmania coincide; they span the period, ca. 9840–9480 cal bp, overlapping the end of the German Preboreal pine and the beginning of the oak chronologies. Our measurements confirm that this part of the calibration curve is a gently sloping 14C-age plateau (ca. 8900–8700 bp, between 10,000 and 9500 cal bp), and suggest interhemispheric 14C differences close to zero.
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11

Belge, Boris, Anna Bara, Tricia Starks, and Christopher J. Ward. "Book Reviews." Sibirica 18, no. 3 (2019): 151–59. http://dx.doi.org/10.3167/sib.2019.180307.

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Smoking under the Tsars: A History of Tobacco in Imperial Russia. Tricia Starks. (Ithaca, NY: Cornell University Press, 2018), xiii + 320 pp. ISBN 978-1-5017-2205-9.White Fox and Icy Seas in the Western Arctic: The Fur Trade, Transportation and Change in the Early Twentieth Century. John R. Bockstoce. (New Haven and London: Yale University Press, 2018), 327 pp., index, illustrations, maps, $40.00 (hardback). ISBN 978-0-300-22179-4.Delo—Tabak: Polveka fabriki “Iava” glazami ee rukovoditelia. Leonid Sinel’nikov. (Moscow: Delo, 2017), 511 pp., ISBN: 978-5-7749-1260-5.Life Histories of Etnos Theory in Russia and Beyond. David G. Anderson, Dmitry V. Arzyutov and Sergei S. Alymov, eds. (Cambridge, UK: Open Book Publishers, 2019), 425 pp., https://doi.org/10.11647/OBP.0150, ISBN 9781783745449.
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12

Orain, R., V. Lebreton, E. Russo Ermolli, et al. "Hominin responses to environmental changes during the Middle Pleistocene in Central and Southern Italy." Climate of the Past Discussions 8, no. 5 (2012): 5181–207. http://dx.doi.org/10.5194/cpd-8-5181-2012.

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Abstract. The palaeobotanical record of early Palaeolithic sites from Western Europe indicates that hominins settled in different kinds of environments. During the "Mid-Pleistocene Transition (MPT)", from about 1 to 0.6 Ma, the transition from 41-ka to 100-ka dominant climatic oscillations, occurring within a long-term cooling trend, was associated with an aridity crisis which strongly modified the ecosystems. Starting from the MPT the more favorable climate of central and southern Italy provided propitious environmental conditions for long-term human occupations even during the glacial times. In fact, the human strategy of territory occupation was certainly driven by the availabilities of resources. Prehistoric sites such as Notarchirico (ca. 680–600 ka), La Pineta (ca. 600–620 ka), Gaudo San Nicola (ca. 380–350 ka) or Ceprano (ca. 345–355 ka) testify to a preferential occupation of the central and southern Apennines valleys during interglacial phases, while later interglacial occupations were oriented towards the coastal plains, as attested by the numerous settlements of the Roma basin (ca. 300 ka). Faunal remains indicate that human subsistence behaviors benefited of a diversity of exploitable ecosystems, from semi-open to closed environments. In central and southern Italy, several palynological records have already illustrated the regional and local scale vegetation dynamic trends. During the Middle Pleistocene climate cycles, mixed mesophytic forests developed during the interglacial periods and withdrew in response to increasing aridity during the glacial episodes. New pollen data from the Boiano basin (Molise, Italy), attest to the evolution of vegetation and climate between OIS 13 and 9 (ca. 500 to 300 ka). In this basin, the persistence of high edaphic humidity, even during the glacial phases, could have favored the establishment of a refuge area for the arboreal flora and provided subsistence resources for the animal and hominin communities during the Middle Pleistocene. This could have constrained human groups to migrate into such a propitious area. Regarding to the local climate evolution during the glacial episodes, the supposed displacement from these sites could be linked to the environmental dynamics solely due to the aridity increase rather than directly to the global climate changes.
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13

Wefel, Jeffrey S., Minhee Won, Andrew Lassman, et al. "CTNI-51. NEUROCOGNITIVE FUNCTION (NCF) OUTCOMES OF RTOG FOUNDATION 3508: A PHASE 3 TRIAL OF ABT-414 WITH CONCURRENT CHEMORADIATION AND ADJUVANT TEMOZOLOMIDE IN PATIENTS WITH EGFR-AMPLIFIED NEWLY DIAGNOSED GBM." Neuro-Oncology 22, Supplement_2 (2020): ii54. http://dx.doi.org/10.1093/neuonc/noaa215.217.

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Abstract RTOG 3508/AbbVie M13-813/INTELLANCE-1 was a phase 3 trial of depatuximab-mafodotin (depatux-m, formerly ABT-414) that accrued 639 patients with EGFR-amplified newly diagnosed GBM. At the pre-specified interim OS analysis, the futility criteria were met and there was no survival benefit from adding depatux-m to SOC. Pre-specified secondary NCF analyses included time to decline in verbal learning and memory as assessed by the HVLT-R Total Recall based on the reliable change index. Exploratory NCF analyses examined changes in other HVLT-R outcomes over time. As corneal epitheliopathy causing visual impairment is a known toxicity of depatux-m, NCF tests that did not depend on visual acuity were employed. NCF testing occurred at baseline, day 1 of the first cycle of adjuvant depatux-m, every other cycle (i.e., 8 weeks) thereafter, and at progression. Compliance with test completion was 95% at screening and 80%, 70%, 58%, 51%, 47% thereafter through cycle 9. The most common reasons for missing data was site error. Time to HVLT-R Total Recall decline trended worse in the depatux-m arm compared to placebo but the difference was not significant (12 month deterioration: 41.2%, 95% CI: 3.50–47.2 vs 32.4%, 95% CI: 26.6- 38.4, p=0.052). The depatux-m arm, in comparison to the placebo arm, showed greater decline from baseline on the HVLT-R at the following time points: cycle 3 (Total Recall: mean= -1.8, SD=5.7 vs mean= -0.5, SD=5.5, respectively, p=0.046; Delayed Recall: mean= -1.1, SD=3.0 vs. mean= -0.2, SD=2.7, respectively, p=0.01), cycle 7 (Total Recall: mean= -0.6, SD=5.1 vs mean= 1.4, SD=5.0, respectively, p=0.009; Delayed Recall: mean -0.6, SD=3.0 vs. mean= 0.5, SD=2.7, respectively, p=0.01), and cycle 9 (Delayed Recall: mean=-0.4, SD=2.7 vs. mean= 0.8, SD=2.4, respectively, p=0.003). Depatux-m added to concurrent chemoradiation and adjuvant temozolomide was associated with faster time to deterioration and worse episodic learning and memory over time than placebo.
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14

WILLNER, ARNE P., HANS-JOACHIM MASSONNE, UWE RING, MASAFUMI SUDO, and STUART N. THOMSON. "P–Tevolution and timing of a late Palaeozoic fore-arc system and its heterogeneous Mesozoic overprint in north-central Chile (latitudes 31–32°S)." Geological Magazine 149, no. 2 (2011): 177–207. http://dx.doi.org/10.1017/s0016756811000641.

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AbstractIn the late Palaeozoic fore-arc system of north-central Chile at latitudes 31–32°S (from the west to the east) three lithotectonic units are telescoped within a short distance by a Mesozoic strike-slip event (derived peakP–Tconditions in brackets): (1) the basally accreted Choapa Metamorphic Complex (CMC; 350–430°C, 6–9 kbar), (2) the frontally accreted Arrayán Formation (AF; 280–320°C, 4–6 kbar) and (3) the retrowedge basin of the Huentelauquén Formation (HF; 280–320°C, 3–4 kbar). In the CMC, Ar–Ar spot ages locally date white-mica formation at peakP–Tconditions and during early exhumation at 279–242 Ma. In a local garnet mica-schist intercalation (570–585°C, 11–13 kbar) Ar–Ar spot ages refer to the ascent from the subduction channel at 307–274 Ma. Portions of the CMC were isobarically heated to 510–580°C at 6.6–8.5 kbar. The age of peakP–Tconditions in the AF can only vaguely be approximated at ≥ 310 Ma by relict fission-track ages consistent with the observation that frontal accretion occurred prior to basal accretion. Zircon fission-track dating indicates cooling below ~ 280°C at ~ 248 Ma in the CMC and the AF, when a regional unconformity also formed. Ar–Ar white-mica spot ages in parts of the CMC and within the entire AF and HF point to heterogeneous resetting during Mesozoic extensional and shortening events at ~ 245–240 Ma, ~ 210–200 Ma, ~ 174–159 Ma and ~ 142–127 Ma. The zircon fission-track ages are locally reset at 109–96 Ma. All resetting of Ar–Ar white-mica ages is proposed to have occurred byin situdissolution/precipitation at low temperature in the presence of locally penetrating hydrous fluids. Hence syn- and postaccretionary events in the fore-arc system can still be distinguished and dated in spite of its complex heterogeneous postaccretional overprint.
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15

Blower, G. "Schilling, R.Measures, integrals and martingales (Cambridge University Press, 2005), xi + 352 pp., 0 521 61525 9 (paperback), £24.99, 0 521 85015 0 (hardback), £50." Proceedings of the Edinburgh Mathematical Society 49, no. 3 (2006): 761–62. http://dx.doi.org/10.1017/s0013091506264939.

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16

Kelly, Ciara Marie, Imelda Parker, John McCaffrey, et al. "Assessment of method of breast cancer detection and Oncotype DX recurrence score." Journal of Clinical Oncology 30, no. 15_suppl (2012): 581. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.581.

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581 Background: Data indicate that screen-detected (SD) cancers show more favourable pathological characteristics and have a better prognosis compared to symptomatic or interval cancers (SY). These findings can be partly explained by length time and lead time biases. OncotypeDX recurrence score (RS) provides prognostic information independent of traditional clinicopathological variables and provides a robust measure of tumour proliferation. The objective of this study was to determine whether the RS would vary depending on the method of detection (MOD) in patients with lymph node-negative, ER-positive, HER-2 negative breast cancer (BC). Methods: We included patients with ER-positive, lymph node-negative and HER2-negative BC who underwent OncotypeDX testing as part of routine care or a clinical trial. We retrospectively reviewed patient charts and extracted information on MOD (SD versus SY), clinicopathological variables and RS. Chi-squared test was used to test for differences between categorical variables and MOD. Analysis of variance (ANOVA) was used to investigate the relationship between RS and MOD and clinicopathological variables. Results: We identified 596 patients from 4 academic hospitals (Mater University Hospital n= 98 (16%), St Vincent’s Hospital n= 161 (27%), Waterford Regional Hospital n= 27 (4%) and University of Texas, MD Anderson Cancer Center n= 310 (52%)). There were 359 (60 %) SD- detected and 237 (40%) SY-detected breast cancers. Clinicopathological variables were similar for age at diagnosis (56 versus 52 years), tumour size (16mm versus 18mm), grade (63% versus 61% grade 2; 15% versus 15% grade I; 21% versus 24% grade 3) and LVI (18% versus 18%) for SY compared to SD, respectively. The number of patients in each group with low (51% versus 50%), intermediate (41% each) or high (8% versus 9%) RS was similar in the SD compared to SY groups, respectively. There was a statistically significant association between RS and tumour grade (P=<0.001) and lymphovascular invasion (P=<0.001). We did not observe a statistically significant association between RS and MOD (P=0.086). Conclusions: In patients with clinically intermediate breast cancer sent for OncotypeDX testing we found no association between RS and MOD.
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17

Fitzpatrick, Colin, Aman Bedi, and Mary Stewart. "How should we refer to people attending sexual health services; patients, clients, users or customers?" Sexual Health 17, no. 2 (2020): 192. http://dx.doi.org/10.1071/sh19199.

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Within the healthcare domain, commercial-sector terminology such as ‘client’, ‘customer’ and ‘user’ are replacing the previously acceptable collective noun, ‘patient’. Is the term we use important to the individuals accessing our services? A paper survey collected the responses of 581 individuals attending the service between August and October 2019. Overall, 372/496 (75%) (95% CI = 71.2–78.8%) unique responses reported a preference to the term ‘patient’, while only 92/496 (19%) (95% CI = 15.1–22.0%) preferred ‘client’, 23/496(5%) (95% CI = 2.8–6.5%) ‘customer’ and 9/496 (2%) (95% CI = 0.6–3.0%) ‘user’. In line with other published data, we acknowledge that people attending our service prefer to be referred to as ‘patient’ above all else.
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18

Yin, Zhi Gang, Jun Feng, Shu You Huang, and Bing Fang Zhao. "Experimental Study of Frost-Resistance Properties of Silica Fume Concrete." Applied Mechanics and Materials 584-586 (July 2014): 1626–29. http://dx.doi.org/10.4028/www.scientific.net/amm.584-586.1626.

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The frost resistance of low strength concrete is researched. In order to evaluate the effect of different content of silica fume on frost resistance,the quality of the cement 6%, 9%, 12% silica fume are respectively added into concrete. Freezing-thawing test results show that: the silica fume concrete has good frost resistance. Content of silica fume on concrete is not almost effect to quality loss rate. In 0-250 times of freezing-thawing cycle range, it is smaller that relative dynamic elastic modulus change rate. Relative dynamic elastic modulus of ordinary concrete decreases rapidly after 250 times of freezing-thawing cycle while dynamic elastic modulus decrease rate of the silica fume concrete tends to slow. The freezing -thawing cycles up to 350 times, silica fume concrete relative dynamic elastic modulus is 1.5 times that of ordinary concrete that show the silica fume concrete frost resistance is better than that of ordinary concrete.
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19

Mikkola, Kauri. "Review: Die Schmetterlinge Baden-Württembergs." Entomologica Fennica 11, no. 1 (2000): 56. http://dx.doi.org/10.33338/ef.84046.

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Ebert, Günter (ed.) 1997, 1997 & 1998: Die Schmetterlinge Baden-Württembergs. Bände 5-7. Sesiidae, Arctiidae, Noctuidae. 575 + 622 + 582 pp., 400 + 512 + 483 colour photographs, 360 + 433 + 329 diagrams and drawings, and 133 + 187 + 170 distribution maps. Verlag Eugen Ulmer. Stuttgart. ISBN 3-8001-3481-0, 3-8001-3482-9, 3-8001-3500-0. Price: Ca. FIM 480,-/part.
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20

Rodrigues, Teresa. "Climate Changes in the western Iberian Margin during Marine Isotope Stages 15-9 (580 TO 300 KA): Suborbital Glacial variability." Quaternary International 279-280 (November 2012): 410. http://dx.doi.org/10.1016/j.quaint.2012.08.1308.

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Bley, Th. "Dynamics of cell and tissue motion. Basel, Boston, Berlin: Birkhäuser, 1997, 352 pages; DM 118.00. ISBN 3-7643-5781-9." Acta Biotechnologica 18, no. 4 (1998): 367. http://dx.doi.org/10.1002/abio.370180413.

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Jolivet SAYA NGOUONIMBA, Hery, OPOYE -ITOUA, MOPOUNDZA Paul, and AKOUANGO Parisse. "Aperçu de quelques paramètres qualitatives dans la caractérisation morpho-biométrique des poules locales (Gallus gallus) ou ‘Batéké’ dans les périphéries Nord et Sud de Brazzaville en République du Congo." Journal of Animal & Plant Sciences 42.2 (November 29, 2019): 7175–97. http://dx.doi.org/10.35759/janmplsci.v42-2.1.

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Cette étude portant sur l’aperçu de quelques paramètres qualitatives dans la caractérisation morpho-biométrique des poules locales (Gallus gallus) ou Batéké dans les périphéries Nord et Sud de Brazzaville avait pour but d’apprécier quelques aspects qualitatifs indispensables dans la caractérisation de ces poules dans les deux périphéries a été réalisée dans les périphéries nord et sud de Brazzaville comprenant respectivement les arrondissements 9 Djiri et 8 Madibou, s’est déroulée dans neuf (9) quartiers au total. A L’issu de cette étude, 929 poulet ont été échantillonnés dont 583 femelles et 346 mâles. Des enquêtes menées ont révélées que 651 poulet (70%) ont une crête simple contre 278(30%) une crête double ; la couleur dominante de la crête est rouge, 922 poulet (99%) contre 9 poulet (1%) de crête rose pâle. 222 poulet (24%), ont un bec jaune, 209 (22%), ont un bec blanc, 154(17%), ont un bec noir, 140(15%), ont un bec corne, 131(14%), ont un bec marron et 73(8%) un bec crème. Les barbillons sont majoritairement de forme ovale 922, soit (99%) contre 7(1%) de forme ronde ; la couleur dominante est le rouge à 100%. Les yeux sont orange clair, 350 poulet (37%), orange foncé, 200 (22%), noir, 150 (16%), yeux bruns 129, (14%), yeux brun foncé, 100 (11%). 378 poulet (41%), ont des tarses blancs, 340 (37%) ont des tarses jaunes, 86 (9%), ont des tarses gris, 78 (8%), ont des tarses pigmenté jaune et 37 (4%)pigmenté noir. La distribution de la couleur a révélé que les phénotypes les plus nombreux sont : blanc (65 poulet soit 7%), fauve uni (61 poulet soit 7%), blanc tacheté (60 poulet soit 6%) ; blanc herminé (60 soit 6%), fauve à queue noir (51 poulet soit 5%). La coloration du plumage est très variable, avec une fréquence élevée des couleurs blanc, fauve uni, blanc tâcheté et blanc herminé. Cette étude fait partie d’une série de travaux en cours de traitement sur les autres aspects qualitatifs et quantitatifs chez cette poule locale. Ngouonimba et al., 2019 Journal of Animal & Plant Sciences (J.Anim.Plant Sci. ISSN 2071-7024) Vol.42 (2): 7175-7197. https://doi.org/10.35759/JAnmPlSci.v42-2.1 7176 SUMMARY This study was focusing on the overvien of some qualitative parameters in the morphobiometrics characterization of local hens (Gallus gallus) in the North and South outskirts of Brazzaville was intended to appreciate some qualitative aspects essential in characterization of these hens in both peripheries has been carried out in the North and South outskirts of Brazzaville, comprising the districts 9 Djiri and 8 Madibou, respectively, in nine (9) quarters in total. At the outcome of this study, 929 chicken were sampled including 583 females and 346 males. Surveys conducted revealed that 651 chicken (70%) have a single Crest against 278 (30%) a double Ridge; the dominant color of the crest is red, 922 chicken (99%) against 9 chicken (1%) of pale pink crest. Also 222 chicken (24%), have a yellow beak, 209 (22%), have a white beak, 154 (17%), have a Black beak, 140 (15%) have a horn beak, 131 (14%) have a Brown beak and 73 (8%) a creamy beak. The barbels are predominantly oval in 922, or (99%) versus 7 (1%) round shape; the dominant color is red at 100%. The eyes are light orange, in 350 chicken (37%), dark orange, 200 (22%), black, 150 (16%), Brown eyes 129, (14%), dark brown eyes, 100 (11%). 378 chicken (41%), have white tarsi, 340 (37%) have yellow tarsi, 86 (9%), have grey tarsi, 78 (8%), have yellow pigmented tarsi and 37 (4%) Pigmented black. Color distribution revealed that the most numerous phenotypes were: white (65 chicken or 7%), United Fawn (61 chicken 7%), white spotted (60 chicken or 6%); white hermined (60 or 6 %) and black-tailed Fawn (51 chicken or 5%). The coloration of the plumage is very variable, with a high frequency of white colors, plain Fawn, white stained and white hermined. This study is part of a series of work being processed on other qualitative and quantitative aspects in this local chicken.
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Kazadzis, S., A. Bais, A. Arola, N. Krotkov, N. Kouremeti, and C. Meleti. "Ozone Monitoring Instrument spectral UV irradiance products: comparison with ground based measurements at an urban environment." Atmospheric Chemistry and Physics 9, no. 2 (2009): 585–94. http://dx.doi.org/10.5194/acp-9-585-2009.

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Abstract. We have compared spectral ultraviolet overpass irradiances from the Ozone Monitoring Instruments (OMI) against ground-based Brewer measurements at Thessaloniki, Greece from September 2004 to December 2007. It is demonstrated that OMI overestimates UV irradiances by 30%, 17% and 13% for 305 nm, 324 nm, and 380 nm respectively and 20% for erythemally weighted irradiance. The bias between OMI and Brewer increases with increasing aerosol absorption optical thickness. We present methodologies that can be applied for correcting this bias based on experimental results derived from the comparison period and also theoretical approaches using radiative transfer model calculations. All correction approaches minimize the bias and the standard deviation of the ratio OMI versus Brewer ratio. According to the results, the best correction approach suggests that the OMI UV product has to be multiplied by a correction factor CA(λ) of the order of 0.8, 0.88 and 0.9 for 305 nm, 324 nm and 380 nm respectively. Limitations and possibilities for applying such methodologies in a global scale are also discussed.
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Kutluk, M. Tezer, and Akif Yesilipek. "Pediatric cancer registry Turkey: 2009-2016 (TPOG & TPHD)." Journal of Clinical Oncology 35, no. 15_suppl (2017): e22015-e22015. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e22015.

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e22015 Background: Each year 300.000 new cancer cases are expected in children & adolescents aged 0-19 years at global level. Although the long term survival rates have been improved to 85% in high income countries it is lower than this LMICs. Pediatric registries are essential for planning, evaluation, comparison for pediatric cancer care. This study focuses to pediatric cancer registry in Turkey. Methods: Turkish Pediatric Oncology Group and Turkish Pediatric Hematology Association established a WEB based cancer registry in Turkey in 2002. The registry information for 2002-2008 was presented earlier. This study, now, is including the distribution of pediatric cancer registry for the years of 2009-2016. International Childhood Classification System was used in classification. Basic demographic findings, ICD-O-3 morphology & topography codes were recorded for each cases. Results: During the 8 years from 2009 to 2016, 13123 pediatric cancer cases were recorded. For all cases, median age was 6.5 year (0–17; M/F 7356/5759, 3 hermaphrodite). Age distribution was 0–4 yrs, 41.3%; 5–9 yrs, 24.3%; 10–14 yrs , 23.2%; 15–19 yrs, 11.0%. 7 cases older than were registered (%0.1). The distribution of tumor types were [number of cases, percentage of total, median age years, M/F]: Leukemia (3751, 28.6%, 5.5, 2148/1603); Lymphoma and other RES tumors (2381, 18.1%, 9.5, 1613/763); CNS [brain & spinal] (1672, 12.7% , 7.13, 908/764); Symphatetic system (1053, 8.0% , 2.42, 550/503); Retinoblastoma (339, 2.6%, 1.33, 188/151); Renal (675, 5.1%, 3.33, 314/361); Liver (217, 1.7% , 1.75, 116/101); Malignant bone (892, 6.8 %, 12.55, 486/406); Soft tissue sarcomas (868, 6.6% , 7.21, 518/350); Germ cell (818, 6.2%, 7.58, 292/523); Carcinoma and other malignant epithelial (391, 3.0% , 13.60, 191/200); Other/non-specific malignant (66, 0.5%, 6.54, 32/34) tumors. Five year survival rate was found as 69.5 %. Conclusions: This registry since 2002 became a critical source for health care professionals in Turkey. Survival rates for children increased from 65% to 70% based on the latest information from this study. This is compatible with Turkey’s development level as an upper middle income country. This data also allows us to use the registry information at national and international studies.
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Demetrio, D., A. Magalhaes, M. Oliveira, R. Santos, and R. Chebel. "11 Invivo-derived embryo pregnancy rates at Maddox Dairy from 2008 to 2018." Reproduction, Fertility and Development 32, no. 2 (2020): 130. http://dx.doi.org/10.1071/rdv32n2ab11.

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Maddox Dairy, located in Riverdale, CA, USA, is a Holstein herd that milks 3500 cows with a 305-day mature-equivalent milk production of 12 800 kg, and they have been producing high genetic animals by embryo transfer (ET) since the early 1980s. Invivo-derived embryos from Holstein donors were transferred fresh (grade 1 or 2) or frozen (grade 1), at morula (4), early blastocyst (5), or blastocyst (6) stage, to virgin heifers (VH, natural oestrus, 13-15 months old) or lactating cows (LC, Presynch-Ovsynch, 86 days in milk, first or second lactation) 6 to 9 days after oestrus. Pregnancy diagnosis was done by transrectal ultrasonography at 32-46 days in VH and by the IDEXX PAG test at 30 days in LC. June, July, August, September, and October were called critical months (first service AI conception rate drops below 44%) and compared with the other months. The data from 32 503 ETs between January 2008 and December 2018 are summarised on Table 1. Pregnancy rates (PR) are lower for LC recipients than for VH. Embryo transfers performed 7 or 8 days after oestrus had higher PR in both types of recipients and embryos, but Day 6 and 9 oestrus are also used with fair results. The season does not seem to affect PR. There is not enough difference in the combination of stage and days from oestrus for invivo-derived embryos. These numbers do not belong to a planned experiment. Several management changes during the years were made, which make it very difficult to apply statistical methods to analyse the data correctly. They are used as a tool to make decisions in an attempt to improve future results. Table 1.Pregnancy rate (PR) of virgin heifers (top) and lactating cows (bottom)-fresh (SH) and frozen (OZ) invivo-derived embryo transfer1 Heat-months SH-ST4 SH-ST5 SH-ST6 SH-All OZ-ST4 OZ-ST5 OZ-ST6 OZ-All PR% n PR% n PR% n PR% n PR% n PR% n PR% n PR% n Heifers 6 d-CM 62 934 66 243 68 69 63 1246 56 473 58 219 62 42 57 734 6 d-OM 62 1623 67 489 69 211 64 2323 56 600 55 296 48 137 55 1033 6 d-T 62 2557 67 732 69 280 63 3569 56 1073 57 515 51 179 56 1767 7 d-CM 64 1506 68 495 67 221 65 2222 60 822 62 340 63 156 61 1318 7 d-OM 66 2723 68 1021 69 510 67 4254 57 1120 59 581 57 231 58 1932 7 d-T 66 4229 68 1516 69 731 67 6476 58 1942 60 921 60 387 59 3250 8 d-CM 65 1348 64 518 67 322 65 2188 59 595 64 258 63 108 61 961 8 d-OM 66 2166 68 886 70 510 67 3562 61 770 60 364 51 130 60 1264 8 d-T 66 3514 67 1404 69 832 66 5750 60 1365 62 622 56 238 60 2225 9 d-CM 60 109 56 43 70 20 60 172 60 5 33 6 50 4 47 15 9 d-OM 58 129 63 57 60 40 60 226 63 16 50 18 75 4 58 38 9 d-T 59 238 60 100 63 60 60 398 62 21 46 24 63 8 55 53 All-CM 64 3897 66 1299 67 632 65 5828 58 1895 61 823 63 310 60 3028 All-OM 65 6641 67 2453 69 1271 66 10 365 58 2506 58 1259 53 502 58 4267 All-T 65 10 538 67 3752 69 1903 66 16 193 58 4401 60 2082 57 812 59 7295 Lactating cows 6 d-CM 54 265 48 86 50 12 53 363 38 141 31 77 50 10 36 228 6 d-OM 49 463 52 203 45 56 50 723 46 101 48 54 59 27 48 182 6 d-T 51 728 51 289 46 68 51 1086 41 242 38 131 57 37 42 410 7 d-CM 54 755 59 274 56 103 55 1137 43 928 48 450 43 192 45 1570 7 d-OM 55 914 66 367 54 109 58 1393 46 1052 45 564 47 353 46 1969 7 d-T 55 1669 63 641 55 212 57 2530 45 1980 46 1014 46 545 45 3539 8 d-CM 63 252 68 82 76 33 65 368 48 219 56 80 42 33 50 332 8 d-OM 61 257 64 161 53 47 61 466 50 191 53 77 56 16 51 284 8 d-T 62 509 65 243 63 80 63 834 49 410 55 157 47 49 50 616 All-CM 56 1272 58 442 60 148 57 1868 44 1288 47 607 43 235 45 2130 All-OM 55 1634 62 731 51 212 56 2582 47 1344 46 695 48 396 47 2435 All-T 55 2906 60 1173 55 360 57 4450 45 2632 47 1302 46 631 46 4565 1ST=stage; CM=critical months (June, July, August, September, and October); OM=other months.
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Bell, Maureen. "Lynette R. Muir The Biblical Drama of Medieval EuropeCambridge: Cambridge University Press, 1995. xxiv, 320 p. ISBN 0-521-41291-9." New Theatre Quarterly 12, no. 47 (1996): 290–91. http://dx.doi.org/10.1017/s0266464x00010319.

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Hughes, Jenny. "Baz Kershaw Theatre Ecology: Environments and Performance EventsCambridge: Cambridge University Press, 2007. 353 p. £55.00. ISBN: 978-0-521-87716-9." New Theatre Quarterly 25, no. 1 (2009): 102–3. http://dx.doi.org/10.1017/s0266464x09000165.

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Levy, Jerome H., Anthony M. Pisacano, and Keith Chadwick. "Astigmatic changes after cataract surgery with 5.1 mm and 3.5 mm sutureless incisions." Journal of Cataract & Refractive Surgery 20, no. 6 (1994): 630–33. http://dx.doi.org/10.1016/s0886-3350(13)80652-9.

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Sadighi, Jila, Saharnaz Nedjat, and Rahele Rostami. "Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide." Public Health Nutrition 22, no. 18 (2019): 3465–84. http://dx.doi.org/10.1017/s1368980019002179.

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AbstractObjective:Assess the effectiveness of iron-fortified flour on iron status.Design:Systematic review and meta-analysis.Setting:Argentina, Australia, Azerbaijan, Bangladesh, Brazil, Cameroon, Chile, China, Costa Rica, Côte d’Ivoire, Denmark, India, Iran, Jordan, Kazakhstan, Kenya, Kuwait, Mongolia, Morocco, Norway, South Africa, Sri Lanka, Tajikistan, Thailand, UK, USA, Uzbekistan, Venezuela, Vietnam, and Zambia.Participants:Fifty-two articles (ninety-four trials) were examined. The main target groups were women, children, and infants/toddlers. The effects of different types of iron-fortified flour (wheat, maize, rice, soy, and beans) on iron status were examined.Results:A random effects analysis of before–after studies showed that iron-fortified flour led to significant increases of mean haemoglobin level (3·360 g/l; 95 % CI: 0·980, 5·730) and mean serum ferritin level (4·518 µg/l; 95 % CI: 2·367, 6·669); significant decreases of anaemia (−6·7 %; 95 % CI: −9·8 %, −3·6 %) and iron deficiency (ID) (−10·4 %; 95 % CI: −14·3 %, −6·5 %); but had no significant effect on iron deficiency anaemia (IDA). A random effects analysis of controlled trials indicated that iron-fortified flour led to significant increases of mean haemoglobin level (2·630 g/l; 95 % CI: 1·310, 3·950) and mean ferritin level (8·544 µg/l; 95 % CI: 6·767, 10·320); and significant decreases of anaemia (−8·1 %; 95 % CI: −11·7 %, −4·4 %), ID (−12·0 %; 95 % CI: −18·9 %, −5·1 %), and IDA (−20·9 %; 95 % CI: −38·4 %, −3·4 %).Conclusions:Flour fortification with iron is an effective public health strategy that improves iron status of populations worldwide.
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SMITH, HANNAH. "COURT STUDIES AND THE COURTS OF EARLY MODERN EUROPE." Historical Journal 49, no. 4 (2006): 1229–38. http://dx.doi.org/10.1017/s0018246x06005802.

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A court in exile: the Stuarts in France, 1689–1718. By Edward Corp. Cambridge: Cambridge University Press, 2004. Pp. xvi+386. ISBN 0-521-58462-0. £55.00.Vienna and Versailles: the courts of Europe's dynastic rivals, 1550–1780. By Jeroen Duindam. Cambridge: Cambridge University Press, 2003. Pp. xi+349. ISBN 0-521-82262-9. £60.00.Intrigue and treason: the Tudor court, 1547–1558. By David Loades. Harlow: Pearson, 2004. Pp. x+326. ISBN 0-582-77226-5. £19.99.Queenship in Europe, 1660–1815: the role of the consort. Edited by Clarissa Campbell Orr. Cambridge: Cambridge University Press, 2004. Pp. xvii+419. ISBN 0-521-81422-7. £60.00.Court culture in Dresden: from Renaissance to Baroque. By Helen Watanabe-O'Kelly. Basingstoke: Palgrave, 2002. Pp. xv+310. ISBN 0-333-98448-X. £47.50.Over the last three decades, the royal or princely court has become an established feature of the historiographical landscape of early modern Europe. The subject of a forest of monographs and theses, the theme of a plethora of university undergraduate courses, it has even gained an Anglo-American academic society (and accompanying journal) dedicated to ‘court studies’. While the first wave of Anglophone court historians, writing in the 1970s and 1980s, considered it necessary to state explicitly, as David Starkey did in his introduction to the seminal The English court, that the study of the early modern court was a legitimate historical activity, such a stance is no longer necessary. Indeed, few political historians would now omit the court from their narratives, even if their principal focus was directed elsewhere. In The English court, Starkey presented his enterprise, and that of his co-contributors, as part of a broader process of historical revisionism. But, by the late 1990s, court studies had itself become subject to its own internal forces of revisionism. The books reviewed here not only illustrate the diversity of projects undertaken by scholars of the court; they also critique the interpretations and approaches of an earlier generation of court historians.
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Seton-Watson, Christopher. "Christopher Duggan, A Concise History of Italy, Cambridge University Press, Cambridge, 1994, xiv + 320 pp., ISBN 0-521-40285-9, £25 hbk, ISBN 0-521-40848-2, £8.95 pbk." Modern Italy 1, no. 1 (1995): 126–27. http://dx.doi.org/10.1017/s1353294400005706.

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Bhattacharya, Abanti. "India–China Relations: Putting the Record Straight." India Quarterly: A Journal of International Affairs 75, no. 2 (2019): 262–68. http://dx.doi.org/10.1177/0974928419841801.

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Tansen Sen, India, China, and the World: A Connected History (New Delhi: Oxford University Press, 2018). Pp. 541, ₹770 (Paperback), ISBN 0-19-948554-2. Berenice Guyot-Rechard, Shadow States: India, China and the Himalayas, 1910–1962 (Delhi: Cambridge University Press, 2017). Pp. 321, ₹550 (Paperback), ISBN 978-1-108-40131-9. Bertil Lintner, China’s India War: Collision Course on the Roof of the World (New Delhi: Oxford University Press, 2018). Pp. 320, ₹675 (Hardcover), ISBN 0-19-947555-5.
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Santos, R., M. Oliveira, N. Melgar, R. Chebel, and D. Demetrio. "9 Pregnancy loss in Holstein lactating recipient cows diagnosed pregnant by pregnancy-associated glycoprotein test in blood." Reproduction, Fertility and Development 32, no. 2 (2020): 129. http://dx.doi.org/10.1071/rdv32n2ab9.

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The objective of this study was to evaluate the pregnancy loss (PL) between Day 30 (P30) and Day 80 (P80) of pregnancy in lactating Holstein recipients that received an invivo- (flush) or invitro-produced (IVF) embryo. The recipient cows were located at Maddox Dairy in Riverdale, CA, USA, a Holstein herd that milks 3500 cows with a 305-day mature-equivalent milk production of 12 800 kg. First-lactation cows were enrolled in a Presynch-Ovsynch oestrus-synchronization program and scheduled to be artificially bred for the first time at 80 days after calving or to receive an embryo 7 or 8 days after the expected heat (recipients). The data from 590 pregnancies (1045 embryo transfers) from embryos transferred between January 2018 and March 2019 was analysed. Only grade 1 embryos (from morula to hatched blastocyst stage) produced invivo or invitro from Holstein donor heifers, lactating or dry cows, were transferred fresh (invivo or invitro) or frozen-thawed (invivo), and pregnancy rates are shown in Table 1. The ruminant trophoblast produces pregnancy-associated glycoproteins (PAG) that can be detected by enzyme-linked immunoassay (ELISA) in the blood of pregnant cattle as early as 28 days after insemination. Various dairy herds in the USA have been using this test to supplement or replace the use of transrectal ultrasonography for early pregnancy diagnosis. Blood was sampled on P30 after expected heat day (23 days after embryo transfer) from the recipient cows and sent to IDEXX for the PAG Bovine Pregnancy Test, which was reconfirmed on P80 of pregnancy by transrectal ultrasonography. Pregnancy loss was considered to have occurred when a cow was pregnant on P30 but not pregnant on P80. The variable PL was analysed by binary logistic regression in the MINITAB program, and the model included effects of donor status (heifer vs. milk vs. dry) and embryo type. The total PL was 12.2% (72/590) and the details are shown in Table 1. No effect of donor status (P=0.80) was detected. However, there was effect of embryo type (P=0.004). The IVF embryos had a PL of 18.0% compared with 9.5% for the invivo-produced embryos. Further research should be performed to study heifer embryos PL, because currently more embryos are being produced from very young donor cows and sires due to intensive use of genomic testing. In conclusion, there is a higher PL in lactating dairy recipients receiving IVF fresh embryos compared with fresh or frozen invivo-produced embryos. Table 1.Embryo transfer (ET) pregnancy rates (PR, P30) in first-lactation Holstein cows (top) and pregnancy loss (PL) from Day 30 (P30) to 80 (P80) in first-lactation recipient Holstein cows (bottom) Item Heifer donor Lactating donor Dry donor Total ET P30 PR% ET P30 PR% ET P30 PR% ET P30 PR% Invivo - fresh 6 3 50.0 43 25 58.1 329 206 62.6 378 234 61.9 Invivo - frozen 75 38 50.7 221 129 58.4 296 167 56.4 IVF - fresh 123 61 49.6 91 42 46.2 157 86 54.8 371 189 50.9 Total 129 64 49.6 209 105 50.2 707 421 59.5 1045 590 56.5 P30 P80 PL% P30 P80 PL% P30 P80 PL% P30 P80 PL% Invivo - fresh 3 3 0.0 25 24 4.0 206 186 9.7 234 213 9.0 Invivo - frozen 38 35 7.9 129 115 10.9 167 150 10.2 IVF - fresh 61 48 21.3 42 35 16.7 86 72 16.3 189 155 18.0 Total 64 51 20.3 105 94 10.5 421 373 11.4 590 518 12.2
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Colish, Marcia L. "Anthony Grafton. What Was History? The Art of History in Early Modern Europe. Cambridge : Cambridge University Press, 2007. x + 320 pp. index. illus. bibl. $65 (cl), $23.99 (pbk). ISBN: 978-0-521-87435-9 (cl), 978-0-521-69714-9 (pbk)." Renaissance Quarterly 60, no. 4 (2007): 1293–95. http://dx.doi.org/10.1353/ren.2007.0419.

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NAKAZAWA, HARUYUKI, HIDEKI HAYASHIDANI, JURI HIGASHI, KEN-ICHI KANEKO, TOSHIO TAKAHASHI, and MASUO OGAWA. "Occurrence of Erysipelothrix spp. in Broiler Chickens at an Abattoir." Journal of Food Protection 61, no. 7 (1998): 907–9. http://dx.doi.org/10.4315/0362-028x-61.7.907.

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From September 1995 to August 1996, 750 chickens from 66 farms sent to an abattoir in Nagano Prefecture, Japan, were examined for the presence of Erysipelothrix spp. Erysipelothrix spp. were isolated from 118 (15.7%) of 750 skin samples, 27 (7.3%) of 372 hypoderm samples, 12 (1.9%) of 630 throat samples, 106 (59.2%) of 179 feather samples, and none of 257 spleen samples. Of 66 farms, 55 farms (83.3%) sent Erysipelothrix-positive chickens and 11 farms (16.7%) only negative ones. Of 297 Erysipelothrix isolates, 273 isolates were identified as Erysipelothrix rhusiopathiae and 24 as Erysipelothrix tonsillarum. E. rhusiopathiae isolates were serotyped into nine different serovars. Of the 273 E. rhusiopathiae isolates, 33 (11.1%) were serotyped to serovar 6; 22 (7.4%) were serovar 5; 19 (6.4%) were serovar 2; 15 (5.1%) were serovar 8; 2 (0.7%) were serovar 21; 4 each (1.3% each) were serovars 1b, 9, 12, and 19; and 178 (59.9%) were untypeable. Of 24 E. tonsillarum isolates, 15 (5.1%) were serotyped to serovar 3, and 9 (3.0%) were serovar 7. These findings indicate that chickens seem to be a potential reservoir of Erysipelothrix spp. in nature and to be a source of human Erysipelothrix infection.
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Cardoso, Antonio Ismael Inácio, and Hisato Hiraki. "Avaliação de doses e épocas de aplicação de nitrato de cálcio em cobertura na cultura do rabanete." Horticultura Brasileira 19, no. 3 (2001): 328–31. http://dx.doi.org/10.1590/s0102-05362001000300007.

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Este experimento foi realizado para avaliar o efeito de doses e épocas de aplicação de nitrogênio em cobertura na cultura do rabanete (cultivar Redondo Vermelho). Foram avaliados sete tratamentos com cinco repetições e parcelas com 1,2 m x 0,8 m (espaçamento de 20 cm x 5 cm), no delineamento experimental em blocos ao acaso. Os tratamentos resultaram da combinação dos fatores época da adubação em cobertura [9 e 20 dias após a semeadura (DAS)] e doses de nitrogênio (100; 200 e 300 kg/ha) na forma de nitrato de cálcio, além da testemunha, sem adubação em cobertura. Em geral, a época de aplicação foi mais importante que o nível de N em cobertura. Quando a adubação foi realizada 9 DAS obteve-se uma produção de 10,30 t/ha de folhas, 10,6 t/ha de raízes (total) e 6,20 t/ha de raízes comerciais, superior à adubação realizada aos 20 DAS (7,7 t/ha, 5,8 t/ha e 2,7 t/ha de folhas, raízes totais e raízes comerciais, respectivamente). Quanto às doses de N, a produção de raízes comerciais foi superior com 300 kg/ha (5,1 t/ha) em comparação a 100 kg/ha (3,6 t/ha). Para as condições em que foi realizado este experimento, as maiores produções de raízes comerciais foram obtidas com 200 ou 300 kg/ha de N, aplicados 9 DAS, recomendando-se 200 kg/ha pelo menor gasto com este insumo.
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Mansfield, Bruce E. "Jill Kraye, ed., The Cambridge Companion to Renaissance Humanism. Cambridge UP, 1996, xviii+320 pp., paperback ISBN 0-521-43624-9, £12.95, $18.95; hardback ISBN 0-521-43038-0, £35.00, $54.95." Moreana 34 (Number 131-, no. 3-4 (1997): 139–44. http://dx.doi.org/10.3366/more.1997.34.3-4.20.

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Visser, Arnoud. "Jill Kraye (ed.), The Cambridge Companion to Renaissance Humanism, (Cambridge University Press, Cambridge-New York-Melbourne 1996) xviii-320 pp. ISBN 0-521-43038-0 (hardback), 0-521-43624-9 (paperback)." Nederlands Archief voor Kerkgeschiedenis / Dutch Review of Church History 78, no. 1 (1998): 118–19. http://dx.doi.org/10.1163/002820392x00329.

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39

Modi, S., A. Stopeck, M. S. Gordon, et al. "Phase I trial of KOS-953, a heat shock protein 90 inhibitor, and trastuzumab (T)." Journal of Clinical Oncology 24, no. 18_suppl (2006): 501. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.501.

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501 Background: KOS-953 (17-AAG in Cremophor) is a potent Hsp90 inhibitor that in vivo induces rapid degradation of Her2, loss of pAKT and tumor growth inhibition in a Her2+ breast cancer xenograft. Objectives: Define the phase 2 dose of KOS-953 + T. Define toxicity and PK of KOS-953, its active metabolite and T. Assess changes in intracellular signaling proteins (such as Hsp70) in leucocytes. Describe antitumor activity. Methods: Eligible pts with advanced solid tumors (Her2 + was not required) received standard weekly doses of T followed by IV KOS-953 in escalating doses over 2 hrs. Results: 25 pts enrolled in 4 cohorts (225, 300, 375 and 450 mg/m2; 4, 3, 8 and 10 patients per cohort), receiving a total of 94 cycles (median 3, range <1 - 12+). Demographics: 21 female (17 with Her2+ metastatic breast cancer ‘MBC‘, 1 Her2 status unknown); median age/KPS 66 yrs/90; # prior T-containing regimens for MBC pts (n=18) equaled 2 (range 0–5). DLT was observed at the 3rd and 4th cohort (1 pt each): 2-week dose delay for recovery from Grade 4 fatigue/Grade 2 nausea & anorexia at 375 mg/m2; delayed recovery of platelets at 450 mg/m2. Drug-related Grade 3 toxicity: emesis, increased ALT and hypersensitivity (n=2); Grade 4 drug-induced thrombocytopenia in a pt with Hashimoto’s disease after 7 cycles. In general the drug was well tolerated. Grade 1 or 2 toxicities included fatigue, nausea, diarrhea, emesis, headache, rash/pruritus, increased AST/ALT and anorexia. Most toxicities (except headache) were not dose dependent. PK of parent (n=21): t½ 3.0 ± 2.1 h; clearance 31.8 ± 12.8 L/h; Vz 164 ± 101 L. Metabolite: Tmax 30–60 min after end-of-infusion with similar AUC and longer t½ of 6.1 ± 1.7 h. PK of T showed no changes compared to previous reports. Among 17 pts with Her2 + MBC s/p multiple regimens of T: PR= 1, MR = 3, 5 pts with SD (5, 7+, 9 and 12+ months). Pts with PR and MRs had confirmed progression of disease prior to study on T-containing regimen. Pharmacodynamic testing showed reactive induction of Hsp70/72 in leucocytes at all dose levels. Conclusions: KOS-953 added to T is active in refractory Her2 + MBC with no change in PK compared to single-agent therapy. The phase 2 dose of KOS-953 is 450 mg/m2; enrollment to the phase 2 trial of this combination in Her2+ MBC is on-going. [Table: see text]
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Oliveira, Luiz Antonio de, and Hélio Paracaima de Magalhães. "Quantitative evaluation of acidity tolerance of root nodule bacteria." Revista de Microbiologia 30, no. 3 (1999): 203–8. http://dx.doi.org/10.1590/s0001-37141999000300004.

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Quantification of acidity tolerance in the laboratory may be the first step in rhizobial strain selection for the Amazon region. The present method evaluated rhizobia in Petri dishes with YMA medium at pH 6.5 (control) and 4.5, using scores of 1.0 (sensitive, "no visible" growth) to 4.0 (tolerant, maximum growth). Growth evaluations were done at 6, 9, 12, 15 and 18 day periods. This method permits preliminary selection of root nodule bacteria from Amazonian soils with statistical precision. Among the 31 rhizobia strains initially tested, the INPA strains 048, 078, and 671 presented scores of 4.0 at both pHs after 9 days of growth. Strain analyses using a less rigorous criterion (growth scores higher than 3.0) included in this highly tolerant group the INPA strains 511, 565, 576, 632, 649, and 658, which grew on the most diluted zone (zone 4) after 9 days. Tolerant strains still must be tested for nitrogen fixation effectiveness, competitiveness for nodule sites, and soil persistence before their recommendation as inoculants.
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41

Costantino, Christina L., Susan Kruse, and David H. Henry. "A Retrospective Chart Review of the Hematologic Consequences of Roux-en-y Gastric Bypass Surgery." Blood 110, no. 11 (2007): 3772. http://dx.doi.org/10.1182/blood.v110.11.3772.3772.

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Abstract Roux-en-y gastric (RYGB) bypass surgery has become increasingly common as a procedure to control overweight/obesity. Due to the resulting bypass of significant amounts of gastric and duodenal mucosa, patients may develop anemia. We reviewed charts of 28 patients who had undergone RYGB surgery in the past 5 years who were referred to us for evaluation. Eighteen of these patients had no hematologic consequences as a result of the surgery. Five patients were anemic but were excluded because they had other causes for anemia than the bypass surgery: myeloma (1), pregnancy (1), breast cancer (1), and heavy menstruation (2). The remaining 5 patients however revealed hematologic abnormalities an average of approximately 23 months following RYGB surgery. In our retrospective chart review, we found anemia most commonly caused by iron deficiency although 1 patient had B12 deficiency, and we suggest periodic follow up of patients months to years after such surgery to screen for anemia from potential malabsorption of iron or B12 from this surgical alteration of gastrointestinal anatomy. Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Months since RYGB & first heme evaluation 24 months 28 months 39 months 11 months 11 months Pre/Post Menopausal pre pre pre pre pre Hemoglobin 8 12.9 9.8 6.7 9.9 B12 165 501 233 340 660 Ferritin 14 9 7 <1 5 Folate 20.8 >24.0 16.3 16.4 >24.0 Creatinine 0.6 0.9 0.9 1.0 0.8 WBC 7.7 8.5 9 6.9 5.6 Platelets 364 300 473 378 462 Reticulocyte Count 1.00% 1.30% 1.20% 1.30% 1.30%
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42

Voelker, A. H. L., T. Rodrigues, K. Billups, et al. "Variations in mid-latitude North Atlantic surface water properties during the mid-Brunhes (MIS 9–14) and their implications for the thermohaline circulation." Climate of the Past 6, no. 4 (2010): 531–52. http://dx.doi.org/10.5194/cp-6-531-2010.

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Abstract. Stable isotope and ice-rafted debris records from three core sites in the mid-latitude North Atlantic (IODP Site U1313, MD01-2446, MD03-2699) are combined with records of ODP Sites 1056/1058 and 980 to reconstruct hydrographic conditions during the middle Pleistocene spanning Marine Isotope Stages (MIS) 9–14 (300–540 ka). Core MD03-2699 is the first high-resolution mid-Brunhes record from the North Atlantic's eastern boundary upwelling system covering the complete MIS 11c interval and MIS 13. The array of sites reflect western and eastern basin boundary current as well as north to south transect sampling of subpolar and transitional water masses and allow the reconstruction of transport pathways in the upper limb of the North Atlantic's circulation. Hydrographic conditions in the surface and deep ocean during peak interglacial MIS 9 and 11 were similar among all the sites with relative stable conditions and confirm prolonged warmth during MIS 11c also for the mid-latitudes. Sea surface temperature (SST) reconstructions further reveal that in the mid-latitude North Atlantic MIS 11c is associated with two plateaus, the younger one of which is slightly warmer. Enhanced subsurface northward heat transport in the eastern boundary current system, especially during early MIS 11c, is denoted by the presence of tropical planktic foraminifer species and raises the question how strongly it impacted the Portuguese upwelling system. Deep water ventilation at the onset of MIS 11c significantly preceded surface water ventilation. Although MIS 13 was generally colder and more variable than the younger interglacials the surface water circulation scheme was the same. The greatest differences between the sites existed during the glacial inceptions and glacials. Then a north – south trending hydrographic front separated the nearshore and offshore waters off Portugal. While offshore waters originated from the North Atlantic Current as indicated by the similarities between the records of IODP Site U1313, ODP Site 980 and MD01-2446, nearshore waters as recorded in core MD03-2699 derived from the Azores Current and thus the subtropical gyre. Except for MIS 12, Azores Current influence seems to be related to eastern boundary system dynamics and not to changes in the Atlantic overturning circulation.
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Akhter, Md Shamim. "A study on pre-retting and post-retting water of waterbodies from a selected area of Bangladesh." JOURNAL OF ADVANCES IN AGRICULTURE 2, no. 1 (2014): 38–41. http://dx.doi.org/10.24297/jaa.v2i1.4252.

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The study was conducted to analyze the pre and post-retting water of five randomly selected ponds regarding the parameters viz. BOD5, COD, TSS, TDS, TKN, TP, CI, PH, Ec PH, and EC. BOD5 (ranging from 110 to 215 mg/l and 170 to 237 mg/l, respectively)and COD (227 mg/l to 310 and 299 to 403 mg/l, respectively)values of both pre and post-retting water of all the ponds were much higher than recommended values. Values of TSS, TKN, TP tests of both pre and post-retting water of the ponds reflected higher values than recommended values. Whereas, TDS(213 to 501 mg/l and 210 to 595 mg/l, respectively) and Cl (51 to 300mg/l and 50 to 305 mg/l, respectively) values were less than recommended values. PH values were within the recommended range of PH 6 to PH 9. All these results indicates that jute-retting is may not be the one and only factor to deteriorate the water quality of ponds. Jute-retting causes transitory water pollution in the water bodies only which can be minimized or removed by different ways. To find out specific way(s) to minimize or eradicate this transitory pollution further research is required.
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44

Jones, Geoffrey. "City Bankers, 1890–1914. By Youssef Cassis · Cambridge and New York: Cambridge University Press, 1994. xv + 350 pp. Charts, graphs, tables, figures, and index. $64.95. ISBN 0-521-44188-9." Business History Review 69, no. 2 (1995): 264–66. http://dx.doi.org/10.2307/3117113.

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45

Kutluk, M. Tezer, and Akif Yeşilipek. "Pediatric cancer registry in Turkey 2009-2019 (TPOG & TPHD)." Journal of Clinical Oncology 38, no. 15_suppl (2020): e22513-e22513. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e22513.

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e22513 Background: The pediatric cancer registry is an essential element of pediatric cancer control. More than 200000 pediatric cancer cases annually are expected in children and adolescents aged 0-14 globally. The current efforts are focusing to improve the survival rates for children and adolescents in LMICs since the survival has already exceeded 80% in most of the high income countries. Here we present the most updated results of the pediatric cancer registry in Turkey. Methods: Pediatric cancer registry has been established by theTurkish Pediatric Oncology Group and Turkish Pediatric Hematology Association in 2002. The childhood cancer cases registered between 2009-2019 was included in this analysis. International Childhood Cancer Classification System was used for the classification. Essential demographic findings, ICD-O-3 morphology and topography codes were recorded for each case. Results: During the 11 years from 2009 to 2019, 17770 cases were registered. For all cases, median age was 6.8 year (0-17; M/F 9973/7789, 3 hermaphrodite, 5 unknown). Age distribution was 0-4 yrs, 40.3%; 5-9 yrs, 24.0%; 10-14 yrs, 23.6%; 15-19 yrs, 12.1%) The distribution of the tumor types were [number of cases, percentage of total, median age yrs, M/F]: Leukemia (4570, 25.7%, 5.5, 2633/1937); Lymphoma & other RES tumors (3477, 19.6%, 9.9, 2324/1150, 1 hermaphrodite & 2 unknown); CNS [brain & spinal] (2493, 14.0%, 6.9, 1363/1129, 1 unkown); Symphatetic system (1426, 8.0%, 2.4, 743/683); Retinoblastoma (348, 2.0%, 1.5, 204/144); Renal (905, 5.1%, 3.2, 435/469, 1 unknown); Liver (304, 1.7%, 1.8, 172/132); Malignant bone (1209, 6.8%, 12.6, 658/551); Soft tissue sarcomas (1221, 6.9%, 7.5, 703/518); Germ cell (1165, 6.6%, 8.8, 426/736, 2 hermaphrodite, 1 unknown); Carcinoma & other malignant epithelial (533, 3.0%, 13.8, 254/279); Other/non-specific malignant (119, 0.7%, 8.5, 58/61). Five year survival rate was found as 71.9%. Conclusions: The data is the most essential part of the cancer control.This registry has been used widely among professionals since its establishment in 2002. Survival rates for children and adolescents has been improved to 70%. This is at the acceptable level for the income level of Turkey which is classified as an upper middle income country. The registry is a useful source for investigators and decision makers at national and international level.
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Korolkova, Tatiyana N., and S. E. Goma. "STUDY OF THE MESOTHERAPY EFFECT WITH EPIPHYSIS PEPTIDES ON THE MOISTURE AND ELASTICITY OF THE SKIN." Russian Journal of Skin and Venereal Diseases 20, no. 5 (2017): 305–10. http://dx.doi.org/10.18821/1560-9588-2017-20-5-305-310.

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Introduction. Mesotherapy is a widely used method of preventing external signs of aging in cosmetology. However, drugs that have proven effectiveness are not enough, therefore epiphyseal peptides are of great interest. Purpose: is to study the effect of intradermal administration of peptide epiphysis on the functional para-meters of the skin. Material and methods. There were 38 women in the research devided into 2 comparable groups. The main group (26 persons) was treated by mesotherapy with epiphyseal peptides. Face, neck and decollete zones were treated by the method of “deep nappage” once a week, 5 procedures per course. Isotonic solution of NaCl was similarly injected into the neck and decollete areas of the control group (12 people). The moisture content (Corneometer CM 825, “Courage & Khazaka”, Germany) and the elasticity (Cutometer MPA 580, “Courage & Khazaka”, Germany) of the skin were determined. Functional skin parameters were evaluated before and after treatment (in both groups) and also on the 1st and 6th months after mesotherapy in the main group. Results. Under the influence of epiphysis peptides the moisture content of the skin increases by 10% after treatment (in the control group without changes) and after 1 month, then decreases by 5% in 6 months below the initial values. In the main group R0 and R8 parameters increase immediately after treatment by 21% and 20% (in the control group R0 and R8 decrease by 4-6%), then decrease by 6-7% and by 28%. The R4 parameter increases immediately after treatment by 20-25% (in the control group it decreases by 13%), then decreases by 12% and 24%; F0 and F1 parameteres increase immediately after treatment by 17% and 22% (in the control group they decrease by 4% and 3%), then decrease by 11% and 9%, by 25% and 28%. Conclusion. The revealed dynamics of skin functional indexes may support the stimulating effect of peptide epiphysis on the cellular elements of the dermis (activation of metabolic processes after treatment and improvement of elasticity parameters by 25-28% after 6 months). Mesotherapy with epiphyseal peptides can be recommended as a method of prevention and correction of age-related skin changes.
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Maddicott, J. R. "England in the thirteenth century. By Alan Harding. (Cambridge Medieval Textbooks.) Pp. xiv + 351. Cambridge: Cambridge University Press, 1993. £37.50. 0 521 30274 9." Journal of Ecclesiastical History 45, no. 3 (1994): 541–42. http://dx.doi.org/10.1017/s0022046900017504.

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48

Charuta, A., R. G. Cooper, M. Pierzchała, and J. O. Horbańczuk. "Computed tomographic analysis of tibiotarsal bone mineral density and content in turkeys as influenced by age and sex." Czech Journal of Animal Science 57, No. 12 (2012): 573–80. http://dx.doi.org/10.17221/6415-cjas.

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Changes in the volumetric bone mineral density (vBMD) and bone mineral content (BMC) of tibiotarsal bones of growing turkeys as affected by birds’ age, sex, and within-the-bone location, respectively, were determined by computed tomography. The research was performed on 165 heavy-type BIG 6 turkeys reared between weeks (wk) 3–16 of age. The computed tomography (pQCT) measurement, conducted at 18 and 50% of the bone length, comprised a bone fragment which was 0.07 mm thick for the compact and the spongious substance collectively. It should be noted that the diaphyses of the tibiotarsal bones in turkeys (580 mg/cm<sup>3</sup>) had greater vBMD than the proximal metaphyses (300 mg/cm<sup>3</sup>), (P ≤ 0.001). BMC was higher in metaphyses for both sexes. Significant differences between the BMC of the metaphyses and the diaphyses were observed in males and females at wk 3 (P ≤ 0.01), 6 (P ≤ 0.05), and 9 (P ≤ 0.001), and at wk 3 (P ≤ 0.05) and 12 (P ≤ 0.01), respectively. vBMD in the diaphyses gradually attenuated with age for both sexes, from 688 mg/cm<sup>3</sup> (wk 3) to 532 mg/cm<sup>3</sup> (wk 16). vBMD of the metaphyses was constant in females, but in males it achieved maximum values of 350 mg/cm<sup>3 </sup>at wk 6 and 12 and minimum of 260 mg/cm<sup>3 </sup>at wk 9 and 16. Correlations between body weight (BW) and vBMD of the diaphyses were observed in males (r = –0.85, P ≤ 0.001) and females (r = –0.52, P ≤ 0.01). It can be concluded that vBMD loss in diaphyses diminished bone-breaking strength leading in investigated turkeys to deformities and bone fractures.
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Schreiber, Roy. "Bruce Lenman, England's Colonial Wars 1550-1688: Conflicts, Empire and National Identity. Harlow, UK: Pearson Education Limited2001. x + 310 pp. ISBN 0-582-06297-7 (hardcover); ISBN 0-582-06296-9 (pbk.)." Itinerario 27, no. 3-4 (2003): 297–99. http://dx.doi.org/10.1017/s0165115300020921.

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50

Martin, Julian. "Roy Porter and Mikuláš Teich (eds.), The Scientific Revolution in National Context. Cambridge: Cambridge University Press, 1992. Pp. xi + 305. ISBN 0-521-39510-0, £35.00 (hardback); 0-521-39699-9, £12.99 (paperback)." British Journal for the History of Science 27, no. 2 (1994): 228–29. http://dx.doi.org/10.1017/s0007087400031988.

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